Rodolphe Fischmeister
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Researcher ORCID ID = 0000-0003-2086-9865
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Why Is Rodolphe Fischmeister Influential?
(Suggest an Edit or Addition)Rodolphe Fischmeister's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation. (1993) (498)
- Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. (1991) (487)
- cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists. (1996) (374)
- Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells (1986) (334)
- Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases. (2006) (326)
- Cyclic Guanosine Monophosphate Compartmentation in Rat Cardiac Myocytes (2006) (288)
- Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation (1991) (237)
- The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes (2007) (218)
- Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle. (1986) (216)
- Cyclic guanosine 3',5'‐monophosphate regulates the calcium current in single cells from frog ventricle. (1987) (200)
- Crosstalk between Rap1 and Rac regulates secretion of sAPPα (2003) (197)
- Nitric oxide regulates the calcium current in isolated human atrial myocytes. (1995) (197)
- Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L‐type Ca2+ current in rat ventricular myocytes (1999) (195)
- A Specific Pattern of Phosphodiesterases Controls the cAMP Signals Generated by Different Gs-Coupled Receptors in Adult Rat Ventricular Myocytes (2006) (184)
- Cloning, Expression, and Pharmacology of Four Human 5‐Hydroxytryptamine4 Receptor Isoforms Produced by Alternative Splicing in the Carboxyl Terminus (1998) (154)
- Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes: Role of Phosphodiesterases (2008) (153)
- Cyclic GMP regulation of the L‐type Ca2+ channel current in human atrial myocytes (2001) (151)
- Calcium-mediated inactivation of the calcium conductance in cesium- loaded frog heart cells (1984) (148)
- Mouse Bestrophin-2 Is a Bona fide Cl− Channel (2004) (138)
- Negative Feedback Exerted by cAMP-dependent Protein Kinase and cAMP Phosphodiesterase on Subsarcolemmal cAMP Signals in Intact Cardiac Myocytes (2004) (136)
- PDEs create local domains of cAMP signaling. (2012) (136)
- Species- and tissue-dependent effects of NO and cyclic GMP on cardiac ion channels. (2005) (135)
- Real-time assessment of myocardial contractility using shear wave imaging. (2011) (132)
- cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes. (1997) (129)
- Volume sensitivity of the bestrophin family of chloride channels (2004) (128)
- Anti‐SSA/Ro52 autoantibodies blocking the cardiac 5‐HT4 serotoninergic receptor could explain neonatal lupus congenital heart block (2000) (124)
- Muscarinic and β-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase (1999) (121)
- Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice. (2011) (120)
- Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. (2013) (116)
- Cardiac Specific Increase in Aldosterone Production Induces Coronary Dysfunction in Aldosterone Synthase–Transgenic Mice (2004) (113)
- Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes. (1995) (111)
- Cyclic adenosine monophosphate phosphodiesterase type 4 protects against atrial arrhythmias. (2012) (111)
- The Human Serotonin 5-HT4 Receptor Regulates Secretion of Non-amyloidogenic Precursor Protein* (2001) (108)
- beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current. (2008) (108)
- Inactivation, reactivation and pacing dependence of calcium current in frog cardiocytes: correlation with current density. (1988) (106)
- Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase (1990) (103)
- Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on &bgr;-Adrenergic cAMP Signals (2009) (100)
- Feedback Control Through cGMP-Dependent Protein Kinase Contributes to Differential Regulation and Compartmentation of cGMP in Rat Cardiac Myocytes (2010) (100)
- SL65.0155, A Novel 5-Hydroxytryptamine4 Receptor Partial Agonist with Potent Cognition-Enhancing Properties (2002) (99)
- Identification of a Tetrahydroquinoline Analog as a Pharmacological Inhibitor of the cAMP-binding Protein Epac* (2012) (97)
- Molecular and functional characterization of a 5‐HT4 receptor cloned from human atrium (1997) (95)
- Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR. (2001) (93)
- Treatments targeting inotropy. (2018) (91)
- Functional expression of the hyperpolarization‐activated, non‐selective cation current If in immortalized HL‐1 cardiomyocytes (2002) (84)
- A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death (2016) (83)
- G protein‐mediated inhibitory effect of a nitric oxide donor on the L‐type Ca2+ current in rat ventricular myocytes (2001) (81)
- Atrial Natriuretic Factor Regulates the Calcium Current in Frog Isolated Cardiac Cells (1988) (80)
- 5-HT4 receptor ligands: applications and new prospects. (2003) (79)
- Muscarinic regulation of the L-type calcium current in isolated cardiac myocytes. (1997) (77)
- Cyclic nucleotide phosphodiesterases in heart and vessels: A therapeutic perspective. (2016) (77)
- Signal transduction by cGMP in heart (1991) (75)
- Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase. (1999) (75)
- Phosphoinositide 3-Kinase &ggr; Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases (2012) (74)
- Regulation of myocardial calcium channels by cyclic AMP metabolism (2004) (74)
- Local response of L‐type Ca2+ current to nitric oxide in frog ventricular myocytes (2001) (73)
- Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following β2‐adrenergic stimulation of ICa,L in frog ventricular myocytes (2003) (73)
- Cyclic AMP compartmentation due to increased cAMP‐phosphodiesterase activity in transgenic mice with a cardiac‐directed expression of the human adenylyl cyclase type 8 (AC8) (2003) (73)
- Isolation of the serotoninergic 5‐HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6‐glial and CHO cell lines (2000) (69)
- Functional expression and regulation of the hyperpolarization activated non‐selective cation current in embryonic stem cell‐derived cardiomyocytes (2000) (69)
- Cardiovascular effects of Urtica dioica L. in isolated rat heart and aorta (2002) (68)
- Constitutive dimerization of human serotonin 5‐HT4 receptors in living cells (2005) (68)
- Direct regulation of cardiac Ca2+ channels by G proteins: neither proven nor necessary? (1992) (67)
- Simultaneous measurements of intracellular cAMP and L‐type Ca2+ current in single frog ventricular myocytes (2001) (67)
- Cyclic AMP phosphodiesterases and Ca2+ current regulation in cardiac cells. (1991) (64)
- Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised Reporting for Model Reproducibility, Interoperability, and Data Sharing (2011) (63)
- Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current (1993) (62)
- Agonist‐independent effects of muscarinic antagonists on Ca2+ and K+ currents in frog and rat cardiac cells. (1993) (61)
- Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation. (2011) (61)
- Induction of neonatal lupus in pups of mice immunized with synthetic peptides derived from amino acid sequences of the serotoninergic 5‐HT4 receptor (2001) (59)
- Cyclic GMP regulates the Ca-channel current in guinea pig ventricular myocytes (1989) (58)
- Effect of forskolin and acetylcholine on calcium current in single isolated cardiac myocytes. (1987) (57)
- Regulation of the amyloid precursor protein ectodomain shedding by the 5‐HT4 receptor and Epac (2005) (57)
- Interactive effects of isoprenaline, forskolin and acetylcholine on Ca2+ current in frog ventricular myocytes. (1989) (57)
- Sequential changes in autonomic regulation of cardiac myocytes after in vivo endotoxin injection in rat. (1999) (57)
- Role of the NO‐cGMP pathway in the muscarinic regulation of the L‐type Ca2+ current in human atrial myocytes (1998) (56)
- Pharmacological characterization of the human 5‐HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells (2000) (55)
- Cyclic AMP synthesis and hydrolysis in the normal and failing heart (2014) (53)
- New VMD2 gene mutations identified in patients affected by Best vitelliform macular dystrophy (2006) (53)
- The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). (2013) (53)
- Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction (2017) (52)
- Regulation of calcium current by low-Km cyclic AMP phosphodiesterases in cardiac cells. (1990) (50)
- Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization. (2007) (49)
- A new regulation of IL-6 production in adult cardiomyocytes by beta-adrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling. (2010) (49)
- Exploration of the ligand binding site of the human 5‐HT4 receptor by site‐directed mutagenesis and molecular modeling (2000) (48)
- Channel currents during spontaneous action potentials in embryonic chick heart cells. The action potential patch clamp. (1984) (48)
- Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes. (2013) (46)
- Methylene blue is a muscarinic antagonist in cardiac myocytes. (1997) (45)
- Post-translational modifications of cardiac tubulin during chronic heart failure in the rat (2002) (45)
- Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart (1999) (44)
- Changes in external Na induce a membrane current related to the Na-Ca exchange in cesium-loaded frog heart cells (1984) (43)
- Arbutus unedo induces endothelium‐dependent relaxation of the isolated rat aorta (2002) (43)
- Augmentation of cardiac contractility with no change in L‐type Ca2+ current in transgenic mice with a cardiac‐directed expression of the human adenylyl cyclase type 8 (AC8) (2002) (43)
- Functional localization of cAMP signalling in cardiac myocytes. (2006) (42)
- Caffeine-induced current in embryonic heart cells: time course and voltage dependence. (1983) (42)
- Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies. (2005) (42)
- Tannins and catechin gallate mediate the vasorelaxant effect of Arbutus unedo on the rat isolated aorta (2004) (42)
- Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein. (1992) (41)
- A comparative study of the effects of three guanylyl cyclase inhibitors on the L‐type Ca2+ and muscarinic K+ currents in frog cardiac myocytes (1997) (41)
- Characterization of Serotonin4 Receptors in Adrenocortical Aldosterone-Producing Adenomas: In Vivo and in Vitro Studies (2002) (40)
- Antihypertensive and vasodilator effects of methanolic extract of Inula viscosa: Biological evaluation and POM analysis of cynarin, chlorogenic acid as potential hypertensive. (2017) (39)
- Post-translational modifications of tubulin and microtubule stability in adult rat ventricular myocytes and immortalized HL-1 cardiomyocytes (2004) (38)
- Is cAMP good or bad? Depends on where it's made. (2006) (37)
- Nitric oxide synthase does not participate in negative inotropic effect of acetylcholine in frog heart. (1996) (37)
- Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus. (2009) (36)
- Interventricular Differences in β‐Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases (2014) (36)
- Characterization of human 5‐HT4(d) receptor desensitization in CHO cells (2003) (34)
- New insights into the human 5‐HT4 receptor binding site: exploration of a hydrophobic pocket (2004) (34)
- Variation of intracellular Ca2+ following Ca2+ current in heart. A theoretical study of ionic diffusion inside a cylindrical cell. (1983) (34)
- Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure (2020) (33)
- NO donors potentiate the β‐adrenergic stimulation of ICa,L and the muscarinic activation of IK,ACh in rat cardiac myocytes (2002) (33)
- Negative Feedback Exerted by PKA and cAMP Phosphodiesterase on Subsarcolemmal cAMP Signals in Intact Cardiac Myocytes (2004) (33)
- Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms, calcium handling proteins and ion channels in human atrial fibrillation. (2007) (32)
- Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart (2018) (32)
- Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes. (2014) (31)
- Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors. (2016) (31)
- Pharmacological characterization of the receptors involved in the β‐adrenoceptor‐mediated stimulation of the L‐type Ca2+ current in frog ventricular myocytes (1997) (30)
- Acetylcholine inhibits Ca2+ current by acting exclusively at a site proximal to adenylyl cyclase in frog cardiac myocytes. (1996) (29)
- The electrogenic Na-Ca exchange and the cardiac electrical activity. I--Simulation on Purkinje fibre action potential. (1981) (29)
- The 5‐HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5‐HT4(c) receptor (1998) (29)
- Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1 (2015) (28)
- High affinity forskolin inhibition of L-type Ca2+ current in cardiac cells. (1990) (26)
- Binding constants determined from Ca2+ current responses to rapid applications and washouts of nifedipine in frog cardiac myocytes. (1996) (26)
- Differential functional effects of two 5-HT4 receptor isoforms in adult cardiomyocytes. (2005) (26)
- Characterization of serotonin(4) receptors in adrenocortical aldosterone-producing adenomas: in vivo and in vitro studies. (2002) (25)
- Some limitations of the cell-attached patch clamp technique: a two-electrode analysis (2004) (24)
- Progression of excitation-contraction coupling defects in doxorubicin cardiotoxicity. (2019) (23)
- Alteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4 (2014) (22)
- Fibroblast growth factor 23 decreases PDE4 expression in heart increasing the risk of cardiac arrhythmia; Klotho opposes these effects (2020) (21)
- Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction. (2019) (21)
- 5‐HT4 Receptor Ligands: Applications and New Prospects (2003) (20)
- Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy. (2015) (20)
- β-Adrenergic cAMP Signals Are Predominantly Regulated by Phosphodiesterase Type 4 in Cultured Adult Rat Aortic Smooth Muscle Cells (2012) (18)
- Ion channels as effectors of cyclic nucleotide pathways: Functional relevance for arterial tone regulation. (2020) (18)
- Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart (1999) (17)
- Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4 receptor and its consequences in early BALB/c mouse embryonic development (2007) (16)
- Cyclic nucleotide signalling compartmentation by PDEs in cultured vascular smooth muscle cells (2019) (16)
- Differential effects of pertussis toxin on the muscarinic regulation of Ca2+ and K+ currents in frog cardiac myocytes (1994) (16)
- Longitudinal distribution of Na+ and Ca2+ channels and β‐adrenoceptors on the sarcolemmal membrane of frog cardiomyocytes (1997) (14)
- Effect of Serotonin4 (5-HT4) Receptor Agonists on Aldosterone Secretion in Idiopathic Hyperaldosteronism (2000) (14)
- Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease (2017) (14)
- Late onset heart failure after childhood chemotherapy. (2019) (14)
- PDE2 regulates membrane potential, respiration and permeability transition of rodent subsarcolemmal cardiac mitochondria. (2019) (13)
- Sympathetic modulation of the effect of nifedipine on myocardial contraction and Ca current in the rat. (1997) (12)
- CSRP3 mediates polyphenols-induced cardioprotection in hypertension. (2019) (12)
- Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms. (2014) (12)
- Synergic PDE3 and PDE4 control intracellular cAMP and cardiac excitation-contraction coupling in a porcine model. (2019) (12)
- Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease? (2016) (12)
- Cyclic AMP signaling in cardiac myocytes (2018) (12)
- PDE4 and mAKAP&bgr; are nodal organizers of &bgr;2-ARs nuclear PKA signalling in cardiac myocytes (2018) (11)
- Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology (2021) (10)
- Regulation of cardiac Ca2+ channels by cGMP and NO (1996) (10)
- New arylpiperazine derivatives as antagonists of the human cloned 5-HT(4) receptor isoforms. (2000) (9)
- RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice (2016) (9)
- Functional studies of the 5'-untranslated region of human 5-HT4 receptor mRNA. (2005) (9)
- Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure (2018) (8)
- Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells. (2017) (8)
- [Regulation of cardiac calcium current by cGMP/NO route]. (1996) (8)
- Cyclic GMP-dependent protein kinase mediates the inhibitory effect of cyclic GMP on calcium current in rat ventricular myocytes (1990) (7)
- Inhibit a Phosphodiesterase to Treat Heart Failure?: This Is the One (2018) (7)
- A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of β-adrenergic and dihydropyridine agonists (1993) (7)
- Agonist-like activity of antibodies directed against the second extracellular loop of the human cardiac serotonin 5-HT4(e) receptor in transfected COS-7 cells. (2002) (7)
- Mapping genetic changes in the cAMP-signaling cascade in human atria. (2021) (7)
- Mouse Bestrophin-2 Is a Bona fide Cl (cid:2) Channel: Identification of a Residue Important in Anion Binding and Conduction (2004) (6)
- A patch-clamp study of the effects of cicletanine on whole-cell calcium current in ventricular myocytes. (1988) (6)
- Cyclic nucleotide signaling and pacemaker activity. (2021) (5)
- Interactive effects of isoprenaline forskolin and acetylcholine on calcium current in single frog ventricular cells (1988) (5)
- Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis (2017) (5)
- A dual effect of cardiac glycosides on Ca current in single cells of frog heart (1986) (5)
- Slow inward Ca current in frog heart: theoretical evidence against a voltage-dependent inactivation. (1982) (5)
- Imipramine as an alternative to formamide to detubulate rat ventricular cardiomyocytes (2019) (5)
- Cyclic nucleotide phosphodiesterases as therapeutic targets in cardiac hypertrophy and heart failure (2022) (4)
- Identification of PDE1 and PDE5 in adult rat left ventricular cardiomyocytes (2007) (4)
- Acute cardiac effects of neuregulin-1/ErbB signalling. (2010) (4)
- A loudspeaker-driven system for rapid and multiple solution exchanges in patch-clamp experiments (1992) (4)
- Enzymatic assays for probing mitochondrial apoptosis. (2015) (4)
- Hormonal and Non-Hormonal Regulation of Ca2+ Current and Adenylate Cyclase in Cardiac Cells (1990) (3)
- [Role of cyclic nucleotide phosphodiesterases type 3 and 4 in cardiac excitation-contraction coupling and arrhythmias]. (2013) (3)
- [β-adrenergic regulation of the L-type Ca2+ current: the missing link eventually discovered]. (2020) (3)
- Limitations of Voltage Qamp Studies of Slow Inward Current Using the Double Sucrose Gap (1982) (3)
- Metabolic Inhibition Induces Transient Increase of L-type Ca2+ Current in Human and Rat Cardiac Myocytes (2019) (3)
- 5 – EHNA as an Inhibitor of PDE2: A Pharmacological and Biochemical Study in Cardiac Myocytes (1996) (3)
- Cyclic Nucleotide Phosphodiesterases and Compartmentation in Normal and Diseased Heart (2017) (3)
- Treatments targeting inotropy A position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association of the European Society of Cardiology (2019) (3)
- β²-adrenergic activation of cardiac Ca²+ current is due to cAMP- dependent phosphorylation in frog ventricle (1996) (2)
- Dynamic and quantitative assessment of myocardial stiffness using Shear Wave Imaging (2010) (2)
- Encyclopedia of biophysics (2013) (2)
- Selective changes in cytosolic β-adrenergic cAMP signals and L-type Calcium Channel regulation by Phosphodiesterases during cardiac hypertrophy. (2020) (2)
- Cyclic AMP synthesis and hydrolysis in the normal and failing heart (2014) (2)
- Pharmacological characterization of the receptors involved in the β-adrenergic stimulation of L-type Ca²+ current in frog ventricular myocytes (1997) (1)
- Type 4 phosphodiesterases control cardiac pacemaker activity (2018) (1)
- Corrigendum to “Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy” [Biochim. Biophys. Acta 1853/11 (2015) 2870–2884] (2016) (1)
- Preliminary characterization of phosphodiesterase-9 in rodent and human pulmonary artery (2020) (1)
- Role of Phosphodiesterases in Cyclic Nucleotide Compartmentation in Cardiac Myocytes (2006) (1)
- [Role of cyclic nucleotide phosphodiesterases in the cAMP compartmentation in cardiac cells]. (2012) (1)
- 0103 : Beneficial effects of berries intake on survival and cardio-renal changes induced by high salt diet in Dahl/SS rat (2015) (1)
- P334Identification of suitable reference genes for gene expression studies in normal and pathological human heart tissues (2014) (1)
- Ion channels: new tools to track cyclic nucleotide changes in living cells (2020) (1)
- [Cyclic nucleotide phosphodiesterases: role in the heart and therapeutic perspectives]. (2016) (1)
- Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs. outer surface membrane (2021) (1)
- Multiple Cyclic GMP Binding Proteins Involved in the Regulation of Cardiac Calcium Channels (1993) (0)
- Chronic treatment with catecholamines favoured spontaneous calcium waves upon β-AR stimulation at the cellular level and promoted susceptibility to ventricular arrhythmias in vivo evoked by catheter-mediated (0)
- Role of the PKA Type I in aorta (2022) (0)
- Anchored-PKA regulates connexin 43 gap junctions communication in the heart (2018) (0)
- PDE4 controls the β-adrenergic stimulation of the cardiac excitation-contraction coupling in right ventricular cardiomyocytes isolated from healthy and heart failure pigs (2018) (0)
- 0256: A screening strategy to identify modulators of the mitochondrial ADP/ATP translocase (ANT) for cardioprotection (2014) (0)
- P2558PDE4 regulates cardiac pacemaker function (2019) (0)
- Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure. (2023) (0)
- Carvedilol sensitizes cardiac beta1-adrenergic receptors by increasing subsarcolemmal cAMP levels through ligand-induced dissociation of PDE4 from beta1-adrenergic receptors (2013) (0)
- A PKA/AKAP signaling complex is essential for regulation of ventricular cardiomyocytes Cx43 gap junction communication (2020) (0)
- 37 – CaV1.2 and β-Adrenergic Regulation of Cardiac Function (2014) (0)
- Cardiac-Specific Overexpression of Phosphodiesterase 2 (PDE2) in Mouse is Cardioprotective (2016) (0)
- Issue Information (2000) (0)
- EPAC1 inhibition protects the heart from doxorubicin-induced toxicity (2021) (0)
- Effects of AAV9-mediated cardiac phosphodiesterase 4B and 2A overexpression in a mouse model of heart failure with preserved ejection fraction (2022) (0)
- PDE2 and PDE5 exert specific and distinct roles in regulating cGMP signals elicited by particulate or soluble guanylyl cyclases in rat cardiac myocytes (2005) (0)
- Pro-Arrhythmic Calcium Waves Induced by Phosphodiesterase Type 4 Inhibition upon Beta-Adrenergic Stimulation Involve Both PKA and CamkII (2014) (0)
- cGMP compartments in cardiac myocytes (2007) (0)
- Real-Time Monitoring of Cyclic Nucleotide Changes in Living Cells (2019) (0)
- 0335 : Contribution of large conductance Ca(2+)-activated K(+) channels to vasorelaxation induced by cAMP-phosphodiesterases inhibitors is blunted in coronary arteries from rats with heart failure (2015) (0)
- Functional expression and regulation of If during cardio-myogenesis (1999) (0)
- Cdo Deficient Mice Display Cardiomyopathy with Alterations in Connexins (2015) (0)
- P514Investigating the mechanistic role of PDE2 in cardiac arrhythmia (2018) (0)
- Cardiac gene therapy with PDE2A limits ventricular remodeling, dysfunction and arrhythmias promoted in mice by chronic infusion with catecholamines (2022) (0)
- Abstract 11397: PDE4 Controls Basal Cyclic AMP Levels and Beta-Adrenergic Signalling in Human Atrium (2010) (0)
- Vascular reactivity of pulmonary artery from PDE9-knockout mice (2020) (0)
- Ligand-grafted nanoparticles as tools to study L-type calcium channel and β-adrenergic receptor function on surface and T-tubule membranes (2019) (0)
- 331 Adenoviral expression of human 5‐HT4 receptors in rat adult cardiac myocytes (2003) (0)
- β-adrenergic/cAMP signaling in doxorubicin-induced cardiotoxicity (2022) (0)
- Simultaneous Recordings of Cell Shortening and cAMP or Calcium Transients Reveal Differential Regulation of Cardiac Contractility by Specific Phosphodiesterases (2009) (0)
- Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1000 words (typed double-spaced) in length and may be subject to editing or abridgment. (2011) (0)
- Type 4 Phosphodiesterase regulates cardiac pacemaker function (2021) (0)
- Loss of PI3K-Gamma Scaffold Function causes Severe Electrical Remodeling in Mice Ventricular Myocytes (2015) (0)
- Decreased phosphodiesterase activities in cardiac hypertrophy: Consequences for β-aR regulation of cAMP and ICa,L (2007) (0)
- PDE8 Mediates L-type Ca2+ Channels Dephosphorylation in Human Atrial Fibrillation (2019) (0)
- Issue Information (2000) (0)
- Regulation of Cardiac Pacemaker Activity by PDE4 Isoforms (2017) (0)
- 0254 Soluble adenylyl cyclase regulates cardiac mitochondrial membrane permeabilization under calcium stress (2014) (0)
- Role of cAMP-phosphodiesterases in cardiac recovery after β–adrenergic stimulation: an in vivo preliminary study (2017) (0)
- PEGylated isoprenaline reveals distinct functions of cardiac β -adrenergic receptors located in the T-tubule vs . outer surface membrane (2022) (0)
- PDE4B is the predominant PDE4 isoform regulating the L-type Ca2+ current in mouse ventricular myocytes (2008) (0)
- Optimization of heart-targeting agents for therapeutic delivery in cardiomyocytes (2020) (0)
- Issue Information (1999) (0)
- Phosphodiesterase type 2 localized in cardiac mitochondria regulates mitochondrial membrane potential, swelling and calcium accumulation (2017) (0)
- 0059: Cyclic AMP response to β-adrenergic stimulation is strongly dependent on cell confluence in vascular smooth muscle cells (2014) (0)
- 0406: Effects of FGF23 and Klotho on adult rat cardiomyocytes in culture (2015) (0)
- PDE4B and PDE4D differentially regulate cardiac pacemaker activity (2021) (0)
- Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes (2005) (0)
- Abstract 17175: Phoshodiesterase 2 - A New Member Of Proteins Involved In Beta-adrenergic Desensitization (2013) (0)
- Opposite effects of cGMP-dependent protein kinase on cGMP production by soluble and particular guanylyl cyclase in adult ventricular myocytes (2007) (0)
- CaV1.2 and β-Adrenergic Regulation of Cardiac Function Overview of the β-adrenergic regulation of L-type calcium channels (2013) (0)
- 3 Cyclic AMP dependent activation of Rac and PAK induced by the serotonin 5‐HT4 receptor (2003) (0)
- Response by Vandecasteele et al to Letter Regarding Article, "Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure". (2021) (0)
- 0097: Role of cAMP phosphodiesterases in the regulation of BK (Ca) channels in rat coronary arteries (2014) (0)
- Novel specific cardiac homing peptides to target failing cardiomyocytes (2022) (0)
- affected by Best vitelliform macular dystrophy gene mutations identified in patients VMD2 New (2007) (0)
- Scientists on the spot: Phosphodiesterases and heart failure. (2020) (0)
- A modification of cAMP compartmentation is involved in the doxorubicin-induced cardiotoxicity (2021) (0)
- Issue Information (1998) (0)
- Investigating the role of PKA type I in the heart (2021) (0)
- Compartmentation of cAMP in Cardiomyocytes (2010) (0)
- Vendredi 3 avril 2009, de 11 h 00 à 12 h 30J014 Simultaneous recordings of cell shortening and camp or calcium transients reveal differential regulation of cardiac contractility by specific phosphodiesterases (2009) (0)
- Differential Regulation of Cytoplasmic and Nuclear PKA Activities by β1- and β2-Adrenoceptors in Adult Cardiac Myocytes (2016) (0)
- Cardiac phenotype of mice with a loss of function in type I cAMP-dependent protein kinase (PKA) (2021) (0)
- The cAMP-dependent protein kinase type I regulates cardiac excitation-contraction coupling (2018) (0)
- 324 Feed‐back inhibition of beta‐adrenergic cAMP signals in cardiac myocytes revealed by expression of cyclic nucleotide‐gated (CNG) channels (2003) (0)
- Cyclic GMP monophosphate compartmentation in rat cardiac myocytes (2006) (0)
- Does cyclic GMP play a role in the regulation of cardiac Ca channel current by neurotransmitters and hormones (1990) (0)
- β-Adrenergic Regulation of Cyclic AMP and Ca Current at the T-Tubules and Surface Membrane in Rat Cardiomyocytes (2014) (0)
- Contribution of BKCa channel to tone regulation by PDE3 and PDE4 depends on the mode of cAMP stimulation and is lost in heart failure (2018) (0)
- Cardiac gene therapy of heart failure with phosphodiesterase PDE4B in mice (2019) (0)
- Issue Information (2001) (0)
- 0340 : BK (Ca) channels contribution to the control of artery tone by PDE3 and PDE4 varies depending on the mode of cAMP stimulation (2016) (0)
- Role of the PKA regulatory subunit RIα in the contractile tone of the aorta (2021) (0)
- Issue Information (2001) (0)
- PDE4 controls the ß-Adrenergic stimulation of the cardiac excitation-contraction coupling in right ventricular cardiomyocytes isolated from healthy and heart failure pigs (2018) (0)
- Response to Letter by Hamilton et al (2011) (0)
- Spatiotemporal regulation of connexin43 gap junction communication in the heart (2017) (0)
- 0270 : CaMKII inhibition prevents cardiac arrhythmias elicited by phosphodiesterases 3 and 4 inhibitors (2015) (0)
- B-adrenergic/cAMP signaling in doxorubicin-induced cardiotoxicity (2022) (0)
- Abstract 26: Myocardial Phosphodiesterase-2A Is Upregulated in Human and Experimental Heart Failure and Blunts Cardiac β-Adrenergic Inotropic Responsiveness (2012) (0)
- PEGylated-Ligands as tools to study β-adrenergic receptor function on surface and T-tubule membranes (2020) (0)
- 0116 : Phosphodiesterases regulate cAMP level in the mitochondria of adult cardiomyocytes (2015) (0)
- Spatiotemporal Regulation of cAMP-Dependent Protein Kinase (PKA) in Cardiac Myocytes (2012) (0)
- 0039: Phosphodiesterase type 4 inhibition enhances pro-arrhythmic spontaneous Ca2+ waves induced by β-adrenergic stimulation: respective role of protein kinase A and Ca2+/calmodulin kinase II (2014) (0)
- Participation of a Fast G Protein Pathway in the ß-Adrenergic Regulation of Cardiac Calcium Channels: Neither Proven nor Needed (1992) (0)
- Abstract 16750: Phosphodiesterase 4B in the L-Type Calcium Channel Complex Regulates Cardiac Calcium Current and Protects Against Ventricular Arrhythmias (2010) (0)
- Control Through cGMP-Dependent Protein Kinase Contributes to Differential Regulation and Compartmentation of cGMP in Rat Cardiac Myocytes (2010) (0)
- P4-400 Alpha secretase activity is selectively activated by the 5-HT4 receptor through EPAC and RAC (2004) (0)
- Optimization of preferential heart drug delivery targeting cardiovascular diseases (2019) (0)
- Cardiac gene therapy with type 2 phosphodiesterase (PDE2) in experimental heart failure: Complementary or alternative to β–blockers? (2022) (0)
- Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease? (2016) (0)
- 0281 : Protection of berries polyphenols in response to cardiac stress might involve other mechanisms than a mitochondrial direct action (2016) (0)
- cAMP increases autocrine IL-1-induced IL-6 production in cardiomyocytes leading to hypertrophic signal transduction pathways (2008) (0)
- 0128 : Regulation of pacemaker activity by PDE4 isoforms (2016) (0)
- Issue Information (2001) (0)
- Beneficial effects of a cardiac gene therapy with phosphodiesterase pde2a in a mouse model of heart failure (2022) (0)
- Novel arylcarbamate and arylurees derivatives, preparations and uses (2001) (0)
- Splicing variants of human serotoninergic receptor 5-HT4 and their applications, in particular for screening (1997) (0)
- A whole-cell patch clamp study of ionic currents in single atrial cells of the tropical toad Bufo marinus. (1987) (0)
- PDE4 regulates cardiac pacemaker function (2020) (0)
- Non-Linear Reduction of Ion Currents in Cultured Cardiac Myocytes: Correlation with a Loss of T-Tubules? (2015) (0)
- Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes (2007) (0)
- 1178Unsuspected role of the cardiac PKA type I in excitation-contraction coupling and in heart failure development (2019) (0)
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