Roger J. Hajjar
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Roger J. Hajjarphilosophy Degrees
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Engineering Philosophy
Roger J. Hajjar's Degrees
- PhD Biomedical Engineering Columbia University
Why Is Roger J. Hajjar Influential?
(Suggest an Edit or Addition)Roger J. Hajjar's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Apoptosis in myocytes in end-stage heart failure. (1996) (1469)
- Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo (2001) (720)
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure (2011) (659)
- Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair (2007) (617)
- Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy (2012) (612)
- Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice (2001) (609)
- Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. (2000) (550)
- Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a. (1999) (507)
- Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. (2009) (453)
- Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure (2001) (453)
- Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome (2012) (434)
- Glycogen Synthase Kinase-3β Is a Negative Regulator of Cardiomyocyte Hypertrophy (2000) (422)
- Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. (1999) (392)
- Improvement in Survival and Cardiac Metabolism After Gene Transfer of Sarcoplasmic Reticulum Ca2+-ATPase in a Rat Model of Heart Failure (2001) (385)
- Functional consequences of caspase activation in cardiac myocytes (2002) (383)
- Inhibition of miR-25 Improves Cardiac Contractility in the Failing Heart (2014) (375)
- Titin Isoform Switch in Ischemic Human Heart Disease (2002) (361)
- Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability (2016) (341)
- Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. (2008) (323)
- Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics. (2019) (323)
- Passive Stiffness Changes Caused by Upregulation of Compliant Titin Isoforms in Human Dilated Cardiomyopathy Hearts (2004) (314)
- SUMO1-dependent modulation of SERCA2a in heart failure (2011) (313)
- Modulation of ventricular function through gene transfer in vivo. (1998) (302)
- Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium. (1990) (282)
- In Vivo Tracking of Stem Cells for Clinical Trials in Cardiovascular Disease (2004) (278)
- Targeting Phospholamban by Gene Transfer in Human Heart Failure (2002) (278)
- Resident c-kit+ cells in the heart are not cardiac stem cells (2015) (268)
- Type 1 Phosphatase, a Negative Regulator of Cardiac Function (2002) (265)
- Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure: Analysis of Recurrent Cardiovascular Events and Mortality (2014) (263)
- FTO-Dependent N6-Methyladenosine Regulates Cardiac Function During Remodeling and Repair (2018) (254)
- Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. (2018) (242)
- Therapeutic Cardiac‐Targeted Delivery of miR‐1 Reverses Pressure Overload–Induced Cardiac Hypertrophy and Attenuates Pathological Remodeling (2013) (232)
- Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. (2000) (232)
- Long-Term Cardiac-Targeted RNA Interference for the Treatment of Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy (2009) (226)
- Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1 (2005) (226)
- Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. (2004) (222)
- Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. (2008) (220)
- Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy. (1998) (218)
- Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. (2004) (217)
- Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy. (2013) (216)
- Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure. (1998) (216)
- Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo (2001) (215)
- Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes. (1997) (213)
- CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. (2007) (206)
- Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases. (1999) (187)
- Angiogenic Mechanisms of Human CD34+ Stem Cell Exosomes in the Repair of Ischemic Hindlimb (2017) (183)
- Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. (2011) (177)
- Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium. (1991) (172)
- AKT signalling in the failing heart (2011) (166)
- SERCA2a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure (2011) (165)
- Distinct Roles of MicroRNA-1 and -499 in Ventricular Specification and Functional Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes (2011) (165)
- Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium (2014) (161)
- Sarcoplasmic reticulum Ca2+ ATPase as a therapeutic target for heart failure (2010) (160)
- Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial (2016) (160)
- Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy (2015) (159)
- Prospects for gene therapy for heart failure. (2000) (158)
- SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway (2012) (154)
- Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals. (2007) (148)
- Critical Role for Stromal Interaction Molecule 1 in Cardiac Hypertrophy (2011) (148)
- Small Molecule‐Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes (2014) (147)
- Altered myocardial calcium cycling and energetics in heart failure--a rational approach for disease treatment. (2015) (144)
- Altered sarcoplasmic reticulum calcium cycling—targets for heart failure therapy (2012) (142)
- Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. (2012) (141)
- Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification (2012) (137)
- Cardiac Sodium Channel Gene Variants and Sudden Cardiac Death in Women (2008) (136)
- Role of resistin in cardiac contractility and hypertrophy. (2008) (135)
- JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure (2012) (135)
- Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b). (2014) (132)
- Sphingosine-1-Phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Porcine Model of Ischemia/Reperfusion (2016) (127)
- The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases (2008) (127)
- Shrink‐Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives (2011) (125)
- Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins. (2007) (124)
- Human heart failure: cAMP stimulation of SR Ca2+-ATPase activity and phosphorylation level of phospholamban. (1999) (124)
- A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. (2011) (123)
- Damped elastic recoil of the titin spring in myofibrils of human myocardium (2003) (122)
- Adenoviral gene transfer of phospholamban in isolated rat cardiomyocytes. Rescue effects by concomitant gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. (1997) (122)
- The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis. (2010) (122)
- Targeted SERCA2a Gene Expression Identifies Molecular Mechanism and Therapeutic Target for Arrhythmogenic Cardiac Alternans (2009) (122)
- Prevention of Ventricular Arrhythmias With Sarcoplasmic Reticulum Ca2+ ATPase Pump Overexpression in a Porcine Model of Ischemia Reperfusion (2008) (119)
- Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders* (2015) (118)
- Ca2+ cycling and new therapeutic approaches for heart failure. (2010) (117)
- Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. (2009) (115)
- Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. (2014) (114)
- A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells. (2014) (111)
- Gene therapy for the treatment of heart failure: promise postponed. (2016) (107)
- Ventricular Arrhythmias after Left Ventricular Assist Device Implantation (2008) (107)
- Targeting calcium cycling proteins in heart failure through gene transfer (2003) (106)
- Inducible Expression of Active Protein Phosphatase-1 Inhibitor-1 Enhances Basal Cardiac Function and Protects Against Ischemia/Reperfusion Injury (2009) (106)
- Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy (2008) (105)
- Targeted Sarcoplasmic Reticulum Ca2+ ATPase 2a Gene Delivery to Restore Electrical Stability in the Failing Heart (2012) (104)
- Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility (2018) (104)
- Relation between steady-state force and intracellular [Ca2+] in intact human myocardium. Index of myofibrillar responsiveness to Ca2+. (1990) (104)
- Human heart failure: cAMP stimulation of SR Ca(2+)-ATPase activity and phosphorylation level of phospholamban. (1999) (101)
- Systems Pharmacology of Adverse Event Mitigation by Drug Combinations (2013) (101)
- Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure (2015) (100)
- Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells. (2007) (100)
- Sarco/Endoplasmic Reticulum Ca2+-ATPase Gene Transfer Reduces Vascular Smooth Muscle Cell Proliferation and Neointima Formation in the Rat (2005) (100)
- Gene therapy: targeting the myocardium (2007) (99)
- Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes (2017) (97)
- Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways* (2011) (95)
- Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells. (2009) (95)
- SUMO-1 Gene Transfer Improves Cardiac Function in a Large-Animal Model of Heart Failure (2013) (95)
- Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c). (2006) (94)
- Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes (2014) (93)
- Plasticity of Surface Structures and &bgr;2-Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure (2012) (91)
- CXCR4 modulates contractility in adult cardiac myocytes. (2006) (91)
- Apoptosis in the failing heart. (1998) (91)
- PICOT Inhibits Cardiac Hypertrophy and Enhances Ventricular Function and Cardiomyocyte Contractility (2006) (91)
- Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis. (2016) (90)
- Characterization of right ventricular remodeling and failure in a chronic pulmonary hypertension model. (2014) (90)
- Therapeutic Efficacy of AAV1.SERCA2a in Monocrotaline-Induced Pulmonary Arterial Hypertension (2013) (90)
- Effect of protein kinase C activation on sarcoplasmic reticulum function and apparent myofibrillar Ca2+ sensitivity in intact and skinned muscles from normal and diseased human myocardium. (1990) (88)
- Cross‐Bridge Dynamics in Human Ventricular Myocardium: Regulation of Contractility in the Failing Heart (1992) (88)
- Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury. (2010) (87)
- Differential effect of DPI 201-106 on the sensitivity of the myofilaments to Ca2+ in intact and skinned trabeculae from control and myopathic human hearts. (1988) (87)
- Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation. (2008) (86)
- SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes. (2001) (85)
- Potential of gene therapy as a treatment for heart failure. (2013) (85)
- Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade. (2005) (83)
- Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration (2020) (82)
- Quantitation of CXCR4 Expression in Myocardial Infarction Using 99mTc-Labeled SDF-1α (2008) (82)
- Ca++ sensitizers impair cardiac relaxation in failing human myocardium. (1997) (82)
- Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling (2016) (80)
- Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART‐1) trial design (2015) (79)
- Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy (2015) (79)
- PICOT Attenuates Cardiac Hypertrophy by Disrupting Calcineurin–NFAT Signaling (2008) (79)
- Functional Near-Infrared Fluorescence Imaging for Cardiac Surgery and Targeted Gene Therapy (2002) (78)
- Rescuing the failing heart by targeted gene transfer. (2011) (78)
- Optimizing Cardiac Delivery of Modified mRNA. (2017) (75)
- Gene therapy for heart failure. (2012) (75)
- Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability (2017) (73)
- Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure (2015) (73)
- Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression. (2016) (72)
- Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells (2017) (72)
- New Efficient Catheter-Based System for Myocardial Gene Delivery (2002) (72)
- Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice (2017) (71)
- Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo (2007) (71)
- Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model. (2007) (70)
- Gene Delivery of Sarcoplasmic Reticulum Calcium ATPase Inhibits Ventricular Remodeling in Ischemic Mitral Regurgitation (2010) (70)
- β2-Adrenergic Receptor Signaling in the Cardiac Myocyte is Modulated by Interactions With CXCR4 (2010) (69)
- Toll-like receptor 2 activation by bacterial peptidoglycan–associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction (2007) (68)
- SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells. (2010) (68)
- RAF1 mutations in childhood-onset dilated cardiomyopathy (2014) (67)
- Genomic correction of familial cardiomyopathy in human engineered cardiac tissues. (2016) (65)
- Stem Cell Factor Gene Transfer Promotes Cardiac Repair After Myocardial Infarction via In Situ Recruitment and Expansion of c-kit+ Cells (2012) (65)
- Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats. (2011) (65)
- PICOT is a critical regulator of cardiac hypertrophy and cardiomyocyte contractility. (2008) (65)
- Cardiac gene therapy with SERCA2a: from bench to bedside. (2011) (64)
- A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility. (2008) (64)
- Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT‐HF randomized phase 2 trial (2017) (64)
- Apoptosis in heart failure and the senescent heart (2007) (64)
- Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo (2007) (63)
- Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias. (2013) (63)
- In Vivo Cardiac Gene Transfer of Kv4.3 Abrogates the Hypertrophic Response in Rats After Aortic Stenosis (2004) (63)
- AAV9.I-1c Delivered via Direct Coronary Infusion in a Porcine Model of Heart Failure Improves Contractility and Mitigates Adverse Remodeling (2013) (63)
- Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. (2014) (63)
- Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness, and Endoplasmic Reticulum: Mitochondrial Calcium Homeostasis in Diastolic and Systolic Heart Failure (2013) (63)
- Functional Near-Infrared Imaging for Cardiac Surgery and Targeted Gene Therapy (2002) (63)
- Novel technique of aortic banding followed by gene transfer during hypertrophy and heart failure. (2002) (62)
- Increased leakage of sarcoplasmic reticulum Ca2+ contributes to abnormal myocyte Ca2+ handling and shortening in sepsis* (2005) (62)
- Early Repair of Moderate Ischemic Mitral Regurgitation Reverses Left Ventricular Remodeling: A Functional and Molecular Study (2007) (62)
- In vivo volumetric analysis of coronary stent using optical coherence tomography with a novel balloon occlusion-flushing catheter: a comparison with intravascular ultrasound. (2005) (61)
- FOXO3a regulates BNIP3 and modulates mitochondrial calcium, dynamics, and function in cardiac stress. (2016) (61)
- Molecular aspects of adrenergic signal transduction in cardiac failure (1998) (61)
- Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. (1991) (61)
- Mitochondrial Morphology, Dynamics, and Function in Human Pressure Overload or Ischemic Heart Disease With Preserved or Reduced Ejection Fraction (2019) (61)
- In vivo tracking in cardiac stem cell-based therapy. (2007) (60)
- Family-Based Approaches to Cardiovascular Health Promotion. (2016) (60)
- The role of SUMO-1 in cardiac oxidative stress and hypertrophy. (2014) (59)
- Effects of Na+/Ca2+-exchanger Overexpression on Excitation–contraction Coupling in Adult Rabbit Ventricular Myocytes (2002) (58)
- Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis. (2014) (58)
- Angiotensin II-induced negative inotropy in rat ventricular myocytes: role of reactive oxygen species and p38 MAPK. (2006) (57)
- Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure. (2001) (57)
- Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. (2000) (57)
- Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure (2019) (57)
- SERCA2a controls the mode of agonist-induced intracellular Ca2+ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells. (2011) (56)
- Human Cardiac Gene Therapy (2018) (56)
- Inhibition of PKC&agr;/&bgr; With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury (2011) (56)
- The role of microRNAs in cardiac development and regenerative capacity. (2016) (56)
- SERCA2a in Heart Failure: Role and Therapeutic Prospects (2005) (55)
- Localization and Quantification of Platelet-Rich Thrombi in Large Blood Vessels With Near-Infrared Fluorescence Imaging (2006) (54)
- Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer. (2006) (54)
- Stimulating Myocardial Regeneration with Periostin Peptide in Large Mammals Improves Function Post-Myocardial Infarction but Increases Myocardial Fibrosis (2013) (54)
- Left Ventricular Unloading Using an Impella CP Improves Coronary Flow and Infarct Zone Perfusion in Ischemic Heart Failure (2018) (52)
- Myofilament calcium regulation in human myocardium. (2000) (52)
- miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy (2018) (51)
- Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response After Myocardial Infarction (2020) (51)
- Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling (2018) (50)
- Myocyte-depleted engineered cardiac tissues support therapeutic potential of mesenchymal stem cells. (2012) (50)
- Long-term angiotensin-converting enzyme inhibition with fosinopril improves depressed responsiveness to Ca2+ in myocytes from aortic-banded rats. (1996) (50)
- Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model. (2016) (49)
- Deletion of delta-like 1 homologue accelerates fibroblast–myofibroblast differentiation and induces myocardial fibrosis (2019) (49)
- Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity (2017) (49)
- Cardionomics: a new integrative approach for screening cardiotoxicity of drug candidates (2009) (49)
- Gene therapy in the treatment of heart failure. (2007) (49)
- Human cardiac-specific cDNA array for idiopathic dilated cardiomyopathy: sex-related differences. (2008) (48)
- Comparison of nonuniform rotational distortion between mechanical IVUS and OCT using a phantom model. (2007) (47)
- Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. (2010) (47)
- Decreased Efficiency of Adenovirus-Mediated Gene Transfer in Aging Cardiomyocytes (2003) (46)
- SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice (2011) (45)
- Intracellular calcium related to force development in twitch contraction of mammalian myocardium. (1990) (45)
- In vivo myocardial distribution of multipotent progenitor cells following intracoronary delivery in a swine model of myocardial infarction. (2009) (44)
- Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure (2010) (44)
- Molecular targets in heart failure gene therapy: current controversies and translational perspectives (2012) (43)
- KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling. (2008) (43)
- Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban. (2009) (43)
- Assessing left ventricular systolic dysfunction after myocardial infarction: are ejection fraction and dP/dt(max) complementary or redundant? (2012) (42)
- Mechanoelectrical remodeling and arrhythmias during progression of hypertrophy (2010) (42)
- In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts. (2005) (41)
- Adrenergic-receptor polymorphisms and heart failure. (2002) (41)
- Increased Stiffness Is the Major Early Abnormality in a Pig Model of Severe Aortic Stenosis and Predisposes to Congestive Heart Failure in the Absence of Systolic Dysfunction (2015) (41)
- Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts. (2007) (41)
- Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells (2018) (41)
- Effectiveness of gene delivery systems for pluripotent and differentiated cells (2015) (40)
- SDF-1 induces TNF-mediated apoptosis in cardiac myocytes (2017) (40)
- Altered Ca2+ sparks and gating properties of ryanodine receptors in aging cardiomyocytes. (2005) (40)
- Cellular and molecular remodeling in a heart failure model treated with the β-blocker carteolol. (1999) (40)
- Tracking stem cells in the cardiovascular system. (2005) (39)
- Gene delivery methods in cardiac gene therapy (2011) (39)
- Adeno-associated virus-mediated gene therapy in cardiovascular disease (2015) (38)
- Characterizing preclinical models of ischemic heart failure: differences between LAD and LCx infarctions. (2014) (38)
- Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin (2013) (37)
- Mesenchymal stem cells in the infarcted heart (2005) (37)
- Late Repair of Ischemic Mitral Regurgitation Does Not Prevent Left Ventricular Remodeling: Importance of Timing for Beneficial Repair (2012) (37)
- Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells (2017) (37)
- Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness, and Endoplasmic ReticulumClinical Perspective (2013) (36)
- Calcium Cycling Proteins and Their Association With Heart Failure (2011) (36)
- Modulation of action potential duration on myocyte hypertrophic pathways. (2006) (35)
- High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy (2015) (35)
- Myocardial stunning in hyperthyroidism (2000) (35)
- Functional alterations in adult rat myocytes after overexpression of phospholamban with use of adenovirus. (1999) (35)
- Signaling pathways mediating the response to hypertrophic stress in the heart. (1999) (35)
- Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of Hypoxia-Inducible Factor-1&agr; and Vascular Endothelial Growth Factor Signaling (2014) (35)
- Direct evidence of changes in myofilament responsiveness to Ca2+ during hypoxia and reoxygenation in myocardium. (1990) (35)
- Mechanisms of Abnormal Calcium Homeostasis in Mutations Responsible for Catecholaminergic Polymorphic Ventricular Tachycardia (2007) (35)
- Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts. (2012) (34)
- A new model of congestive heart failure in rats. (2011) (34)
- Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway. (2012) (34)
- Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter. (2004) (33)
- Targeted gene therapy for the treatment of heart failure. (2011) (33)
- Stem Cell Factor Gene Transfer Improves Cardiac Function After Myocardial Infarction in Swine (2012) (33)
- Gene Transfer of Parvalbumin Improves Diastolic Dysfunction in Senescent Myocytes (2004) (33)
- Effects of Na(+)/Ca(2+)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes. (2002) (33)
- Child Health Promotion in Underserved Communities: The FAMILIA Trial. (2019) (33)
- miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure. (2017) (32)
- Pathophysiological and biochemical characterisation of an avian model of dilated cardiomyopathy: comparison to findings in human dilated cardiomyopathy. (1993) (32)
- Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome. (2021) (32)
- Swine Model of Chronic Postcapillary Pulmonary Hypertension with Right Ventricular Remodeling: Long-Term Characterization by Cardiac Catheterization, Magnetic Resonance, and Pathology (2014) (32)
- Overexpression of sorcin enhances cardiac contractility in vivo and in vitro. (2005) (31)
- Expression of active protein phosphatase 1 inhibitor-1 attenuates chronic beta-agonist-induced cardiac apoptosis (2010) (31)
- Aortic implantation of mesenchymal stem cells after aneurysm injury in a porcine model. (2011) (31)
- Gene Remodeling in Type 2 Diabetic Cardiomyopathy and Its Phenotypic Rescue with SERCA2a (2009) (31)
- Cellular and molecular remodeling in a heart failure model treated with the beta-blocker carteolol. (1999) (31)
- CXCR4 gene transfer prevents pressure overload induced heart failure. (2012) (30)
- Guidelines for Translational Research in Heart Failure (2015) (30)
- Atrial Infarction and Ischemic Mitral Regurgitation Contribute to Post-MI Remodeling of the Left Atrium. (2017) (30)
- Phospholamban as a Crucial Determinant of the Inotropic Response of Human Pluripotent Stem Cell–Derived Ventricular Cardiomyocytes and Engineered 3-Dimensional Tissue Constructs (2015) (30)
- Oscillations of intracellular calcium induced by vasopressin in individual fura-2-loaded mesangial cells. Frequency dependence on basal calcium concentration, agonist concentration, and temperature. (1991) (30)
- Differences in cardioprotective efficacy of adrenergic receptor antagonists and Ca2+ channel antagonists in an animal model of dilated cardiomyopathy. Effects on gross morphology, global cardiac function, and twitch force. (1993) (30)
- Imaging in cardiac cell-based therapy: in vivo tracking of the biological fate of therapeutic cells (2008) (29)
- Overexpression of SERCA2a accelerates repolarisation in rabbit ventricular myocytes. (2002) (29)
- Percutaneous Approaches for Efficient Cardiac Gene Delivery (2013) (29)
- SERCA 2 a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure (2011) (29)
- Assessment of Cardiovascular Fibrosis Using Novel Fluorescent Probes (2011) (28)
- Introducing Genes to the Heart: All About Delivery (2017) (28)
- Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. (2012) (28)
- Xanthine oxidase inhibition and heart failure: novel therapeutic strategy for ventricular dysfunction? (2006) (28)
- Gene profiling during regression of pressure overload-induced cardiac hypertrophy. (2007) (28)
- Chronic treatment with Carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure (2003) (27)
- Protein Phosphatase Inhibitor-1 Gene Therapy in a Swine Model of Nonischemic Heart Failure. (2017) (27)
- Targeting sarcoplasmic reticulum calcium ATPase by gene therapy. (2013) (26)
- Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms (2013) (26)
- Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure. (2013) (26)
- Intracellular devastation in heart failure (2008) (26)
- PICOT increases cardiac contractility by inhibiting PKCζ activity. (2012) (26)
- CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Human Medium- and Large-Sized Arteries (2018) (25)
- Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart FailureNovelty and Significance (2014) (25)
- Molecular Imaging of Apoptosis in Ischemia Reperfusion Injury With Radiolabeled Duramycin Targeting Phosphatidylethanolamine: Effective Target Uptake and Reduced Nontarget Organ Radiation Burden. (2018) (25)
- Up‐regulation of micro‐RNA765 in human failing hearts is associated with post‐transcriptional regulation of protein phosphatase inhibitor‐1 and depressed contractility (2015) (25)
- Effect of a high omega-3 fatty acid diet on cardiac contractile performance in Oncorhynchus mykiss. (1996) (24)
- High capsid-genome correlation facilitates creation of AAV libraries for directed evolution. (2015) (24)
- Interaction between increased SERCA2a activity and beta -adrenoceptor stimulation in adult rabbit myocytes. (2002) (24)
- Post-translational Modifications in Heart Failure: Small Changes, Big Impact. (2016) (24)
- Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: a new aspect in therapy of cardiovascular diseases. (2013) (24)
- Cardiac Stim 1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC 2 / Akt Signaling (2016) (23)
- Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus (2009) (23)
- SERCA2a gene transfer prevents intimal proliferation in an organ culture of human internal mammary artery (2012) (23)
- Synergistic Role of Protein Phosphatase Inhibitor 1 and Sarco/Endoplasmic Reticulum Ca2+-ATPase in the Acquisition of the Contractile Phenotype of Arterial Smooth Muscle Cells (2014) (23)
- Effect of Bortezomib on the Efficacy of AAV9.SERCA2a Treatment to Preserve Cardiac Function in a Rat Pressure-Overload Model of Heart Failure (2014) (23)
- EMPAGLIFLOZIN INDUCES A MYOCARDIAL METABOLIC SHIFT FROM GLUCOSE CONSUMPTION TO KETONE METABOLISM THAT MITIGATES ADVERSE CARDIAC REMODELING AND IMPROVES MYOCARDIAL CONTRACTILITY (2018) (23)
- Calcium-activated force in a turkey model of spontaneous dilated cardiomyopathy: adaptive changes in thin myofilament Ca2+ regulation with resultant implications on contractile performance. (1992) (23)
- Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. (2011) (23)
- Mechanism of action of 2,3-butanedione monoxime on contracture during metabolic inhibition. (1994) (22)
- Variability in coronary artery anatomy affects consistency of cardiac damage after myocardial infarction in mice. (2017) (22)
- Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes. (2018) (21)
- Development of a preclinical model of ischemic cardiomyopathy in swine. (2011) (21)
- Acute Left Ventricular Unloading Reduces Atrial Stretch and Inhibits Atrial Arrhythmias. (2018) (21)
- Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction. (2019) (21)
- Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression. (2016) (21)
- Comparison of echocardiographic measurements of left ventricular volumes to full volume magnetic resonance imaging in normal and diseased rats. (2013) (21)
- Mitochondrial Integrity and Function in the Progression of Early Pressure Overload–Induced Left Ventricular Remodeling (2017) (21)
- Concurrent upregulation of endogenous proapoptotic and antiapoptotic factors in failing human hearts (2009) (20)
- The transcription factor Eya2 prevents pressure overload-induced adverse cardiac remodeling. (2009) (20)
- The Phospholamban Journey 4 Decades After Setting Out for Ithaka. (2017) (20)
- Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy. (2015) (20)
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-2002. A 55-year-old man with second-degree atrioventricular block and chest pain. (2002) (20)
- Efficient transduction of vascular smooth muscle cells with a translational AAV2.5 vector: a new perspective for in-stent restenosis gene therapy (2013) (20)
- Targeting Ca2+ cycling proteins and the action potential in heart failure by gene transfer (2002) (20)
- Calcineurin inhibitors and cardiac hypertrophy (1999) (19)
- Transcriptional changes following restoration of SERCA2a levels in failing rat hearts (2004) (19)
- Molecular targets of current and prospective heart failure therapies (2013) (19)
- Use of Adeno-Associated Virus Vector for Cardiac Gene Delivery in Large-Animal Surgical Models of Heart Failure. (2017) (19)
- Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling (2016) (19)
- Efficient viral gene transfer to rodent hearts in vivo. (2003) (19)
- AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis. (2019) (19)
- Gene transfer for ischemic heart failure in a preclinical model. (2011) (18)
- Pericardial Fluid Exosomes: A New Material to Treat Cardiovascular Disease. (2017) (18)
- Gene transfer in cardiac myocytes. (2004) (18)
- HAX-1 regulates SERCA2a oxidation and degradation. (2018) (18)
- CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response (2017) (18)
- The force-interval relationship in human myocardium. (1995) (18)
- Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. (2012) (18)
- Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKC&agr;/Gal‐3 pathway reduces left ventricular fibrosis following myocardial infarction (2018) (18)
- Axial stretch-dependent cation entry in dystrophic cardiomyopathy: Involvement of several TRPs channels. (2016) (18)
- Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats. (2009) (18)
- Gene Therapy in Cardiac Surgery: Clinical Trials, Challenges, and Perspectives. (2016) (17)
- Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension. (2019) (17)
- Pulmonary Artery Hypertension Model in Rats by Monocrotaline Administration. (2018) (17)
- Active Inhibitor-1 Maintains Protein Hyper-Phosphorylation in Aging Hearts and Halts Remodeling in Failing Hearts (2013) (17)
- Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer (2019) (16)
- Increased Afterload Following Myocardial Infarction Promotes Conduction-Dependent Arrhythmias That Are Unmasked by Hypokalemia (2017) (16)
- Sarco (Endo) Plasmic Reticulum Calcium Atpases (SERCA) Isoforms in the Normal and Diseased Cardiac, Vascular and Skeletal Muscle (2013) (16)
- CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy (2019) (16)
- Stroke volume-to-wall stress ratio as a load-adjusted and stiffness-adjusted indicator of ventricular systolic performance in chronic loading. (2012) (16)
- The Sugen 5416/Hypoxia Mouse Model of Pulmonary Arterial Hypertension. (2018) (15)
- Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Due to a Human Myosin Regulatory Light Chain Mutation. (2019) (15)
- Cardiopoietic stem cell therapy in ischaemic heart failure: long‐term clinical outcomes (2020) (15)
- Experimental models of cardiac physiology and pathology (2019) (15)
- Molecular components of transient outward potassium current in cultured neonatal rat ventricular myocytes (2002) (15)
- Gene Therapy for Heart Failure: Where Do We Stand? (2013) (15)
- Responsiveness of the myofilaments to Ca2+ in human heart failure: implications for Ca2+ and force regulation. (1992) (15)
- Modulation of calcium-activation in control and pressure--overload hypertrophied ferret hearts: effect of DPI 201-106 on myofilament calcium responsiveness. (1991) (15)
- Combination Proximal Pulmonary Artery Coiling and Distal Embolization Induces Chronic Elevations in Pulmonary Artery Pressure in Swine (2015) (15)
- Calcium-sensitizing inotropic agents in the treatment of heart failure: A critical view (1991) (15)
- Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy. (2020) (15)
- Cardiac Gene Therapy: From Concept to Reality (2012) (15)
- Rationale and Design of Family‐Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA) (2017) (15)
- Contractile effects of adenovirally-mediated increases in SERCA2a activity: A comparison between adult rat and rabbit ventricular myocytes (2003) (15)
- Abnormalities of capillary microarchitecture in a rat model of coronary ischemic congestive heart failure. (2015) (15)
- Ventricular pressure and dimension measurements in mice. (1999) (14)
- Safety and long-term efficacy of AAV1.SERCA2a using nebulizer delivery in a pig model of pulmonary hypertension (2018) (14)
- Sarcoplasmic reticulum and calcium cycling targeting by gene therapy (2012) (14)
- Treatment of heart failure by calcium cycling gene therapy. (2007) (14)
- Decoy peptides targeted to protein phosphatase 1 inhibit dephosphorylation of phospholamban in cardiomyocytes. (2013) (14)
- Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes. (2008) (14)
- [Ca2+]i in human heart failure: a review and discussion of current areas of controversy. (1994) (14)
- A pilot study of a new chicken model of alcohol-induced cardiomyopathy. (1999) (13)
- AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure (2012) (13)
- Na / Ca 2 exchanger-1 protects against systolic failure in the Akitains 2 model of diabetic cardiomyopathy via a CXCR 4 / NF-B pathway (2012) (13)
- Combining neuroendocrine inhibitors in heart failure: reflections on safety and efficacy. (2007) (13)
- Abstract 10606: Plasticity of Surface Structures and Beta 2-adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure (2011) (12)
- Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter (2004) (12)
- RESISTIN AGGRAVATES ATHEROSCLEROSIS IN APOE-/- MICE AND IS ELEVATED IN HUMAN ATHEROSCLEROTIC LESIONS (2019) (12)
- Mitral Valve Prolapse: A Disease of Valve and Ventricle. (2018) (12)
- Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. (2015) (12)
- Comparison of Left Ventricular Stroke Volume Assessment by Two‐ and Three‐Dimensional Echocardiography in a Swine Model of Acute Myocardial Infarction Validated by Thermodilution Method (2012) (12)
- Cardiac gene therapy. (2010) (11)
- Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies (2021) (11)
- Safe and Sustained Overexpression of Functional Apolipoprotein A-I/High-density Lipoprotein in Apolipoprotein A-I–null Mice by Muscular Adeno-associated Viral Serotype 8 Vector Gene Transfer (2009) (11)
- A novel secreted-cAMP pathway inhibits pulmonary hypertension via a feed-forward mechanism. (2019) (11)
- Direct reprogramming induces vascular regeneration post muscle ischemic injury (2021) (10)
- Clopidogrel and CYP2C19 testing: ready for clinical prime time? (2012) (10)
- Therapeutic Efficacy of AAV 1 . SERCA 2 a in Monocrotaline-Induced Pulmonary Arterial Hypertension (2013) (10)
- Calcium Cycling in Synthetic and Contractile Phasic or Tonic Vascular Smooth Muscle Cells (2012) (10)
- A series of robust genetic indicators for definitive identification of cardiomyocytes. (2016) (9)
- Modeling CVD in human pluripotent cells by genome editing. (2014) (9)
- Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of HIF-1α and VEGF Signaling (2014) (9)
- A Pig Model of Myocardial Infarction: Catheter-Based Approaches. (2018) (9)
- Heart Failure: A Silver bullet to treat heart failure (2006) (9)
- Candesartan abrogates G protein-coupled receptors agonist-induced MAPK activation and cardiac myocyte hypertrophy (2001) (9)
- Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues (2019) (9)
- Adeno-associated Virus Serotype 8 ApoA-I Gene Transfer Reduces Progression of Atherosclerosis in ApoE-KO Mice: Comparison of Intramuscular and Intravenous Administration (2011) (9)
- Yin-Yang 1 transcription factor modulates ST2 expression during adverse cardiac remodeling post-myocardial infarction. (2019) (9)
- AAV vectors and cardiovascular disease: Targeting TNF receptor in the heart: clue to way forward with AAV? (2007) (9)
- Abstract 15439: AAV-Containing Exosomes as a Novel Vector to Improve AAV-Mediated Myocardial Gene Delivery in Resistance to Neutralizing Antibody (2017) (8)
- Gene therapies for arrhythmias in heart failure (2014) (8)
- Angiotensin II-induced negative inotropy in rat ventricular myocytes : role of reactive oxygen species and p 38 MAPK (2005) (8)
- Surgical and physiological challenges in the development of left and right heart failure in rat models (2019) (8)
- PRESERVATION OF MECHANICAL AND ENERGETIC FUNCTION AFTER ADENOVIRAL GENE TRANSFER IN NORMAL RAT HEARTS (2007) (8)
- Targeted gene transfer in heart failure: implications for novel gene identification. (2004) (8)
- Speckle-Tracking Echocardiographic Strain Analysis Reliably Estimates Degree of Acute LV Unloading During Mechanical LV Support by Impella (2018) (8)
- Conventional Method of Transverse Aortic Constriction in Mice. (2018) (8)
- Fingerprint profile of alcohol-associated heart failure in human hearts. (2008) (8)
- Ischemic Model of Heart Failure in Rats and Mice. (2018) (8)
- The impact of pressure overload on coronary vascular changes following myocardial infarction in rats. (2013) (8)
- Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues (2020) (7)
- A role for calcium in resistin transcriptional activation in diabetic hearts (2018) (7)
- Mesenchymal Stem Cells & Endothelial Function (2015) (7)
- The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats. (2019) (7)
- Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues (2019) (7)
- Temporal changes of strain parameters in the progress of chronic ischemia: with comparison to transmural infarction (2012) (7)
- Gene therapy for the treatment of catecholaminergic polymorphic ventricular tachycardia. (2014) (7)
- Comparison of Incidences of Congestive Heart Failure in Older African-Americans, Hispanics, and Whites (1999) (7)
- Specific Modified mRNA Translation System. (2020) (7)
- Chronic Erythropoietin Treatment Decreases Post-Infarct Myocardial Damage in Rats without Venous Thrombogenic Effect (2008) (7)
- Clinical correlates of the myocardial force-frequency relationship in patients with end-stage heart failure. (1997) (7)
- Primary Effect of SERCA2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction (2018) (7)
- Tracking stem cells in vivo. (2006) (7)
- Telomerase and the aging heart. (2003) (7)
- Echocardiographic and hemodynamic assessment for predicting early clinical events in severe acute mitral regurgitation (2018) (7)
- THE SGLT2 INHIBITOR EMPAGLIFLOZIN DOES NOT EXHIBIT PRO THROMBOTIC EFFECTS (2018) (6)
- Gene Therapy for Heart Failure (2012) (6)
- Gene therapy for the treatment of heart failure--calcium signaling. (2003) (6)
- Extrapericardial cardiac tamponade after blunt chest trauma. (1995) (6)
- Effects of pH and temperature on myocardial calcium-activation in Pterygoplichthys (catfish) (1998) (6)
- Therapeutic Delivery of Pip4k2c‐Modified mRNA Attenuates Cardiac Hypertrophy and Fibrosis in the Failing Heart (2021) (6)
- Cardiac cell and gene therapies: two trajectories, one goal (2008) (6)
- Gene therapy for heart failure. (2001) (6)
- Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias (2021) (6)
- Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation (2021) (6)
- The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice (2016) (6)
- Stem cell therapy for acute myocardial infarction: on the horizon or still a dream? (2017) (6)
- Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques. (2017) (6)
- Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs. (2017) (6)
- Role of the PRC2-Six1-miR-25 signaling axis in heart failure. (2019) (6)
- Intracellular Free Calcium in Hypertrophy and Failure (1994) (5)
- Myocardial delivery of stromal cell-derived factor 1 in patients with ischemic heart disease: safe and promising. (2013) (5)
- Transgenic models of heart failure: elucidation of the molecular mechanisms of heart disease. (2005) (5)
- Advances in Gene-Based Therapy for Heart Failure (2008) (5)
- Method of gene delivery in large animal models of cardiovascular diseases. (2011) (5)
- Progress in Gene Therapy for Heart Failure (2014) (5)
- Allele-specific silencing ameliorates restrictive cardiomyopathy due to a human myosin regulatory light chain mutation (2019) (5)
- Heart Function Challenged with β-Receptor Agonism or Antagonism in a Heart Failure Model (2001) (5)
- A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity. (2018) (5)
- Labeling galectin-3 for the assessment of myocardial infarction in rats (2014) (5)
- Synthetic MicroRNAs Stimulate Cardiac Repair. (2017) (5)
- PLN Foundation. (2018) (5)
- Cellular and molecular remodeling in a heart failure model treated with the b-blocker carteolol (1999) (5)
- Current Methods in Cardiac Gene Therapy: Overview. (2017) (5)
- Basic Concepts in Heart Failure Ca 2 Cycling and New Therapeutic Approaches for Heart Failure (2010) (5)
- Refilling Intracellular Calcium Stores. (2010) (5)
- Enhancing atrial‐specific gene expression using a calsequestrin cis‐regulatory module 4 with a sarcolipin promoter (2018) (5)
- 3D-ECHOCARDIOGRAPHY DEMONSTRATES EXCELLENT CORRELATION WITH CARDIAC MAGNETIC RESONANCE FOR ASSESSMENT OF LEFT VENTRICULAR FUNCTION AND VOLUMES IN A MODEL OF MYOCARDIAL INFARCTION (2012) (4)
- Genetic maneuvers to ameliorate ventricular function in heart failure: therapeutic potential and future implications (2005) (4)
- Is contractility depressed in the failing human heart? (1995) (4)
- Sarco/Endoplasmic Reticulum Ca2+-ATPase is a more effective calcium remover than Sodium-Calcium Exchanger in human embryonic stem cell-derived cardiomyocytes. (2019) (4)
- Direct Myocardial Injection of Vectors. (2017) (4)
- Anellovirus Structure Reveals a Mechanism for Immune Evasion (2022) (4)
- Overexpression of sorcin improves cardiac excitation-contraction coupling in normal and failing ventricular cardiomyocytes (2003) (4)
- Rescue of Ca2+ Overload-induced Left Ventricle Dysfunction by Targeted Ablation of Phospholamban (2005) (4)
- Tracking cell therapy: bioluminescence lighting the way. (2012) (4)
- Targeting signaling pathways in heart failure by gene transfer (2003) (4)
- Modulating signaling pathways in hypertrophy and heart failure by gene transfer. (2002) (4)
- Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modeling a European cardiomyopathy with global impact. (2022) (4)
- Inhaled Gene Transfer for Pulmonary Circulation. (2017) (4)
- Pulmonary hypertension arising from left heart disease causes intrapulmonary venous arterialization in rats. (2018) (4)
- Myofibrillar responsiveness to cAMP, PKA, and caffeine in an animal model of heart failure. (2003) (4)
- Cardiac signal transduction (2000) (4)
- Modeling Pulmonary Hypertension: A Pig Model of Postcapillary Pulmonary Hypertension. (2018) (4)
- A novel efficient percutaneous myocardial gene delivery system (2002) (4)
- Stem cell and gene therapy for cardiac regeneration (2014) (4)
- Reduced longitudinal contraction is associated with ischemic mitral regurgitation after posterior MI. (2018) (4)
- transcription factor NFAT and proliferation in human vascular smooth muscle cells (2011) (4)
- Preclinical animal models for testing iPSC/ESC-based heart therapy (2012) (3)
- Genetic editing of dysfunctional myocardium. (2003) (3)
- Catheter‐based ventricle‐coronary vein bypass (2005) (3)
- Adenoviral gene transfer of SERCA2a improves iv function in aortic-banded rats in transition to heart failure (1998) (3)
- Characterization of the Differential Progression of Left Ventricular Remodeling in a Rat Model of Pressure Overload Induced Heart Failure. Does Clip Size Matter? (2018) (3)
- Abstract 20916: Therapeutic Cardiac-Targeted Delivery of Mir-1 Reverses Hypertrophy and Preserves Cardiac Function in a Pressure Overload Animal Model. (2010) (3)
- Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors (2012) (3)
- Swine Model of Mitral Regurgitation Induced Heart Failure. (2018) (3)
- Coronary capillary blood flow in a rat model of congestive heart failure. (2018) (3)
- Echocardiographic Left Ventricular Mass Estimation: Two-Dimensional Area-Length Method is Superior to M-Mode Linear Method in Swine Models of Cardiac Diseases (2019) (3)
- Targeted SERCA2a Gene Delivery to Restore Electrical Stability in the Failing Heart (2012) (3)
- Differences in Cardioprotective Efficacy of Adrenergic Receptor Antagonists and Ca 21 Channel Antagonists in an Animal Model of Dilated Cardiomyopathy (2005) (3)
- Monday, 27 August 2012 (2012) (3)
- Revisiting Old Players in the Revitalized Field of Cardiovascular Gene Therapy. (2015) (3)
- Myocardial Cannabinoid Receptor Imaging in Obesity. (2018) (3)
- Gene Transfer to Rodent Hearts In Vivo. (2017) (3)
- The promise of gene therapy as a therapeutic modality in heart failure. (2000) (3)
- Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model. (2020) (3)
- A Decoy Peptide Targeted to Protein Phosphatase 1 Attenuates Degradation of SERCA2a in Vascular Smooth Muscle Cells (2016) (2)
- Antisense strategies for treatment of heart failure. (2005) (2)
- Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells. (2017) (2)
- Orthotopic heart transplantation in patients with cardiac amyloidosis (2005) (2)
- Cardiac fibrosis and miR-433. (2016) (2)
- Abstract 18618: Endothelial to Mesenchymal Transition Contributes to Atherosclerotic Plaque Formation and Correlates With Plaque Instability (2016) (2)
- overload-induced cardiac hypertrophy Gene profiling during regression of pressure (2015) (2)
- Abstract 20344: CCN5 Reverses Fibrosis and Cardiac Dysfunction Induced by Pressure Overload in Murine Models (2014) (2)
- The matricellular protein CCN5 prevents adverse atrial structural and electrical remodelling (2020) (2)
- Abstract 18442: Modeling Drug-Induced Long QT Syndrome with Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2014) (2)
- Improved recovery of ventricular contractility with injection of self-assembling peptide nanofiber scaffolds after myocardial infarction in a rat model (2009) (2)
- Abstract 12012: Dysregulated Adenosine Methylation of RNA in Myocardial Ischemia (2016) (2)
- Magnetic resonance assessment of myocardial perfusion via catheter‐based ventricle–coronary vein bypass in porcine myocardial infarction model (2006) (2)
- Abstract 919: Neonatal Gene Transfer of SERCA2a Alters Hypertrophic Gene Expression and Improves the Response to {beta}-Adrenergic Stimulation in a FHC {alpha}-Tropomyosin (Glu180Gly) Mouse Model (2006) (2)
- Abstract 5331: Gene Transfer Of The Peripheral Type Benzodiazepine Receptor Alters The Spatio-temporal Dynamics Of The Mitochondrial Membrane Potential ({Delta}{Psi}M) Across The Intact Heart (2008) (2)
- Technique of Complete Heart Isolation with Continuous Cardiac Perfusion During Cardiopulmonary Bypass: New Opportunities for Gene Therapy. (2018) (2)
- Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
- Chronic Pulmonary Artery Embolization Models in Large Animals. (2018) (2)
- Protein kinase C activation in human ventricular myocardium. (1991) (2)
- Abstract 1083: Targeted SERCA2a Gene Overexpression Identifies Mechanism and Potential Therapy for Arrhythmogenic Cardiac Alternans (2007) (2)
- Direct measurement of left atrial and pulmonary artery pressure in rats with pulmonary hypertension. (2018) (2)
- Abstract 16977: MicroRNA-mediated Regulation of SUMO1 Expression in Heart (2014) (2)
- Abstract 18200: Intracoronary Delivery of Bioabsorbable Alginate Matrix (IK-5001) Ameliorates Adverse Post-infarction Left Ventricular Remodeling and Improves Left Ventricular Function in a Porcine Model of Reperfused Myocardial Infarction (2015) (2)
- Restoration of contractile function in isolated failing human ventricular cardiac myocytes by gene transfer of SERCA2a (1999) (2)
- Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model (2011) (2)
- 230. In Vivo Fluorescence Tracking System for Cardiac Stem Cell Therapy (2006) (2)
- Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies (2022) (2)
- ALTERED Ca2+ CYCLING IN RAT HEART DURING SPESIS (2003) (2)
- Gene and protein-based therapies for improving cardiac performance and regeneration (2020) (2)
- Manipulation of SERCA2a in the heart by gene transfer (2000) (2)
- Abstract 16566: T1 Mapping Calculated from Look-Locker Sequences Reliably Assesses Interstitial Myocardial Fibrosis Compared with Histology, and Diastolic Dysfunction (2012) (1)
- Resistin Promotes Cardiac Hypertrophy via AMPK / mTOR and JNK / IRS 1 Pathways (2011) (1)
- Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy (2023) (1)
- Accuracy of Non-fluoroscopic Catheter-based Electromechanically-guided (NOGA) Mononuclear Cell Endocardial Injection in a Swine Myocardial Infarction Model Assessed by MRI (2009) (1)
- In silico Cell Therapy Model Restores Failing Human Myocyte Electrophysiology and Calcium Cycling in Fibrotic Myocardium (2022) (1)
- Abstract 18434: Modulation of N6-Methyladenosine (m6A) as a Novel Mechanism of Human CD34+ Stem Cell-Derived Exosomes in Cardiac Repair (2017) (1)
- Abstract 17367: Infusion of the Ketone Body β-Hydroxybutyrate Improves Left Ventricular Systolic Function in an Animal Model of Heart Failure With Reduced Ejection Fraction (2018) (1)
- Efficient Viral Gene Transfer to Rat Hearts In Vivo (2011) (1)
- Calcium Homeostasis in Human Heart Failure (1998) (1)
- MicroRNA-25 upregulation protects spinal cords, yet is bad for the heart: The dark side of noncoding RNAS. (2019) (1)
- [Hopes for gene therapy for cardiac failure]. (2006) (1)
- Endo-bronchial aerosolized AAV1.SERCA2a gene therapy in a pulmonary hypertension pig model: addressing the lung delivery bottleneck. (2022) (1)
- Differential effects of cAMP and protein kinase A on sacroplasmic reticulum Ca2+uptake in falling and nonfalling human myocardium (1996) (1)
- Of Mice and Men. (2018) (1)
- Abnormal sarcoplasmic reticulum Ca2+activity and uptake in human heart failure (1996) (1)
- Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai Translational Mission. (2017) (1)
- Targeting genes and cells in the progression to heart failure. (2005) (1)
- Reply to "Letter to the editor: Characterizing preclinical model of ischemic heart failure: difference between LAD and LCx infarctions". (2015) (1)
- Abstract 17984: Validating the Gold-standard: Steady-State Free Precession Sequence for Assessment of Left Ventricular and Right Ventricular Mass (2014) (1)
- Child Health Promotion in UnderservedCommunities (2019) (1)
- Abstract 17407: Modulation of N6-Methyladenosine (m6A) by the Fat Mass Obesity-Associated Gene (FTO) Regulates Cardiac Function (2017) (1)
- Corrigendum to “Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy” [Biochim. Biophys. Acta 1853/11 (2015) 2870–2884] (2016) (1)
- Abstract 104: AAV-Exosomes: A Novel Platform for Myocardial Gene Delivery for Cardioprotection (2018) (1)
- Abstract 18088: Myocardial Delivery of Lipidoid Nanoparticle mRNA Designed for Tailored Expression of Cardiogenic Factors (2013) (1)
- Abnormal Calcium Metabolism in Heart Muscle Dysfunction (1993) (1)
- Abstract 3911: A Novel Small Molecule Approach for Treating Mechano-electrical Dysfunction in Heart Failure (2009) (1)
- Intra-scar perfusion heterogeneity by cardiac magnetic resonance in a porcine model of non-reperfused myocardial infarction. (2014) (1)
- Cardiovascular Gene Therapy (2013) (1)
- Animal model of left atrial thrombus in congestive heart failure in rats. (2019) (1)
- Multimodality Imaging of Chronic Ischemia (2010) (1)
- Abstract 3807: Chronic Cardiac-Targeted RNA Interference for the Treatment of Severe Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy (2008) (1)
- Abstract 2704: Early Repair of Moderate Ischemic MR Reverses LV Remodeling: A Functional and Molecular Study (2006) (1)
- Cardiac gene therapy: Kick-starting calcium cycling in rats (2005) (1)
- Abstract 3669: Transcoronary Gene Transfer of Serca2a Enhances Coronary Blood Flow through an Increase of eNOS Activity in Endothelial Cells (2008) (1)
- Abstract 746: The Effect of Aging-related Metabolic Disorder on Resistin Expression and Valvular Heart Disorder (2019) (1)
- THE SGLT2 INHIBITOR EMPAGLIFLOZIN IMPROVES DIASTOLIC FUNCTION IN A HEART FAILURE MODEL MEDIATED VIA ENHANCED MYOCARDIAL KETONE METABOLISM (2019) (1)
- CUPID 1: MYDICAR® in Patients With Advanced Heart Failure Continue to Demonstrate Improvement in Clinical Outcomes Compared to Optimal Therapy 9 Months Post-Dose (2010) (1)
- 1029-22 Effect of Cyclic GMP in Human Myocardium: Role of cAMP/cGMP Balance (1995) (1)
- Abstract 16448: Adult Human Cardiac Progenitor Cells Enhance Contractile Force in Human Engineered Cardiac Tissues (2018) (1)
- 237. Gene Expression Profiles in Diabetic Cardiomyopathy Following SERCA2a Gene Transfer (2006) (1)
- in vivo Tracking and Effects of SPIO‐labeled Mesenchymal Stem Cells in a Porcine Model of Abdominal Aortic Aneurysm (2015) (1)
- Titin--springing back to youth? (2002) (1)
- Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues (2019) (1)
- Abstract P482: Elucidating And Characterizing The Molecular Mechanistic Role Of Phospholamban L39 Stop In The Pathophysiology Of Cardiomyopathy Using Patient-derived Human Induced Pluripotent Stem Cells And Humanized Knock-in Mouse Model Systems (2021) (1)
- Human anelloviruses produced by recombinant expression of synthetic genomes (2022) (1)
- Abstract 16186: Hypoxic Pre-conditioning on Human CD34+ Stem Cells Enhances Exosome Therapeutics of Ischemic Tissue Repair Through ETS-1-Regulated Pathway (2015) (1)
- Abstract 12: M6A Modification in RNA Regulates Cardiomyocyte and Cardiac Function in Heart Failure (2017) (1)
- Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts. (2022) (1)
- Chapter 46 – Cardiac Gene Therapy (2012) (1)
- Abstract 10667: Long Term Follow-up of Patients With Advanced Heart Failure Following a Single Intracoronary Infusion of Aav1/serca2a (2013) (1)
- Abstract 18698: Identification of a Novel Cardiac Progenitor Population Expressing Pw1/peg3 in the Murine Heart (2014) (1)
- Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues (2021) (1)
- Scar Size and Other Parameters for Tracking Left Ventricular Dysfunction after Induction of Myocardial Infarcts in Sheep (Ovisaries). (2018) (1)
- Inflammation and Heart Failure: Friend or Foe? (2021) (1)
- Abstract 18635: Development of a Swine Model of Chronic Postcapillary Pulmonary Hypertension: Long Term Characterization by Cardiac Catheterization, Magnetic Resonance and Pathology (2013) (1)
- Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues (2019) (0)
- Lentiviral-Mediated Interleukin-10 Gene Therapy for Lung Transplantation. (2019) (0)
- Heart Failure Targeted Sarcoplasmic Reticulum Ca ATPase 2a Gene Delivery to Restore Electrical Stability in the Failing Heart (2012) (0)
- Deletion Of P 53 In Endothelial Cells Prevents Cardiac Fibrosis And Heart Failure Induced By Pressure Overload In Mice Via Enhanced Angiogenesis (2013) (0)
- Abstract 16892: Beneficial Effect of miR-25 Decoy Overexpression in a Murine Model of Heart Failure (2014) (0)
- Abstract 19040: Exome Sequencing of Extreme Phenotypes Identifies B4GALT2 as a Determinant of Clopidogrel Response Variability (2014) (0)
- The Regenerative Potential of Mesenchymal Stem Cells in a Porcine Abdominal Aortic Aneurysm Model (2013) (0)
- Intratracheal Gene Delivery of SIN3A Inhibits Pulmonary Arterial Hypertension and Restores BMPR2 Expression (2020) (0)
- Phospholamban down-regulation or SERCA2a overexpression: Interaction with βAR stimulation in rabbit myocytes (2001) (0)
- Abstract 17897: Pharmacological Inhibition of PTEN Increases Myocardial Salvage, Reduces Infarct Size, and Decreases Adverse Post-infarction Left Ventricular Remodeling in a Porcine Model of Reperfused Myocardial Infarction (2014) (0)
- Rescue of Ca 2 (cid:1) overload-induced left ventriclur dysfunction by targeted ablation of phospholamban (2009) (0)
- Abstract 18964: Resveratrol Prevents Iron-overload Cardiomyopathy by up Regulating Serca2a and by Exerting Anti-oxidant Effects (2014) (0)
- 118. In Vivo Tracking of Long Term Gene Expression of AAV1 Using Fluorescence Imaging System (2006) (0)
- Abstract 142: Modeling Drug-Induced Long QT Syndrome with Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2013) (0)
- Abstract 17357: Direct Cardiac Reprogramming Using Combinatorial Modified mRNA (2020) (0)
- Abstract 20214: Ethnic Disparities in Metabolic Syndrome Among Caregivers of Preschool Children in a Community-Based Trial (2017) (0)
- Therapeutic Targeted Delivery of AAV9 Sh BNIP3 Reverses Cardiac Remodeling and Improves Diastolic and Systolic Function in a Rat Model of Pressure Overload Induced Heart Failure (2012) (0)
- Abstract 113: SUMO1 Gene Transfer Rescues Cardiac Function in a Large Animal Model of Heart Failure (2012) (0)
- QS243. Analysis of Cell Based Therapy for Abdominal Aortic Aneurysms: Results of a Pilot Study in a Porcine Model (2009) (0)
- Gene and cell therapy in heart failure. (2005) (0)
- Anti- and proarrhythmic effects of cardiac assist device implantation (2011) (0)
- Synergistic Role of Protein Phosphatase Inhibitor 1 and SERCA2a in the Acquisition of the Contractile Phenotype of Arterial Smooth Muscle Cells (2013) (0)
- STEM CELL FACTOR OVER–EXPRESSION IMPROVES CARDIAC FUNCTION AFTER MYOCARDIAL INFARCTION IN SWINE (2013) (0)
- Intratracheal SERCA2a Gene Therapy Interrupts the Formation of Plexiform Lesions and Rescues from Heart Failure in Severe Pulmonary Arterial Hypertension (2019) (0)
- Abstract 16635: Real Time 3d Echocardiography is Comparable to Cardiac Mri in Reducing Sample Size Required to Assess Changes in Lv Function (2012) (0)
- Tilemann Model of Heart Failure Gene Transfer Improves Cardiac Function in a Large-Animal SUMO-1 (2013) (0)
- Abstract 15984: Alternatively Spliced Tissue Factor Exerts Greater Angiogenic Potency than Full-Length Tissue Factor via HIF-1a Induction in Complicated Atherosclerotic Plaques (2013) (0)
- Abstract 842: Potential Role of MicroRNAs in the Pathogenesis of Diabetic Cardiomyopathy (2008) (0)
- P936Yin-Yang 1 transcription factor modulates sST2 on adverse cardiac remodeling post-myocardial infarction (2018) (0)
- Backx Molecular components of transient outward potassium current in cultured neonatal rat ventricular myocytes (0)
- PS196. Tracking the Migration of Porcine Mesenchymal Stem Cells with the MRI Contrast Agent Ferex in an AAA Model (2012) (0)
- 1029-175 Anti-ErbB2 modulation of Bcl-xL/Bcl-xScauses mitochondrial dysfunction and apoptosis (2004) (0)
- Abstract 943: In Vivo Assessment of Mesenchymal Stem Cells Fate Following Intracoronary Delivery (2006) (0)
- Abstract 3805: Hemodynamic and Molecular Effects of Resistin Overexpression on Cardiovascular Function In Vivo (2008) (0)
- AAV meets exosomes: at the cutting edge of cardiovascular gene therapy (2018) (0)
- LOW DOSE ASPIRIN FOR PRIMARY PREVENTION OF CARDIOVASCULAR DISEASE: USE PATTERNS AND IMPACT ACROSS RACE IN THE SOUTHERN COMMUNITY COHORT STUDY (2018) (0)
- A first-in-human phase 1 clinical gene therapy trial for the treatment of heart failure using a novel rationally designed cardiotropic adeno-associated vector (2022) (0)
- Cable Tension Optimization for an Epicardial Parallel Wire Robot (2023) (0)
- GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIVATION WITH LIRAGLUTIDE DURING MYOCARDIAL ISCHEMIA DECREASES INFARCT SIZE AND IMPROVES SYSTOLIC LEFT VENTRICULAR FUNCTION (2013) (0)
- Abstract 431: The Capillaries in Ischemic Border Zone: Origin And Role in Myocardial Infarction and Heart Failure (2019) (0)
- Abstract 530: Mechanisms Underlying Phospholamban L39 Stop (PLN L39X) Cardiomyopathy (2020) (0)
- Coronary heart disease In vivo myocardial distribution of multipotent progenitor cells following intracoronary delivery in a swine model of myocardial infarction (2009) (0)
- Abstract 123: SUMO1 Modification Regulates SR Calcium ATPase Pump, SERCA2a in Heart Failure (2012) (0)
- BCVS scientific conference 2012 meeting report. (2012) (0)
- P374Expression pattern of sarco (endo) plasmic reticulum calcium atpases (SERCA) isoforms in normal and diseased mouse cardiovascular tissues (2014) (0)
- Phosphorylation regulates association of PDE3A isoforms with distinct interactomes (1013.23) (2014) (0)
- Inhibition of PKC (cid:1) / (cid:2) With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury (2011) (0)
- Abstract 373: An Animal Model of Left Atrial Thrombus (2018) (0)
- Abstract 18587: Downregulation of Pulmonary Artery Endothelial Catechol-o-methyltransferase Activity by Aldosterone Increases Norepinephrine Levels in Pulmonary Arterial Hypertension (2014) (0)
- Racial Disparities in Early Subclinical Atherosclerosis: Insights from the FAMILIA Study (2018) (0)
- Abstract 18398: Prevention of Pulmonary Hypertension with Intra-tracheal Delivery of AAV1.SERCA2A (2010) (0)
- 919-12 Transient Wall Motion Abnormalities Following Rotational Coronary Atherectomy are Reflective of Myocardial Stunning More than Microinfarction (1995) (0)
- Abstract 486: Increased Afterload In Sub-acute Phase Of Myocardial Infarction Exacerbates Heart Failure (2013) (0)
- P1-6: Attenuation of cardiac hypertrophy by transient outward K+ current (2006) (0)
- Editorial Board (2009) (0)
- Abstract 17732: Identification of Stromal Interaction Molecule 1 Complexes in Cardiac Hypertrophy (2014) (0)
- Targeting the SERCA-PLB Complex for Treatment of Heart Failure (2016) (0)
- Abstract 12379: Glucagon-Like Peptide-1 Receptor Activation During Myocardial Ischemia Causes Short- and Long-Term Improvements in Myocardial Infarction Size and Left Ventricular Function (2011) (0)
- 776-6 Myocardial Adenylyl Cyclase Activity in an Animal Model of Dilated Cardiomyopathy Treated Chronically with the Non-Selective β-blocker Carteolol (1995) (0)
- Author response: Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells (2016) (0)
- Abstract 129: Human Mesenchymal Stem Cells Augment Contractile Function of Human Engineered Cardiac Tissues (2013) (0)
- Abstract P281: A Novel Mutation in Adiponectin Receptor 1 Contributes to Cardiac Hypertrophy and Cardiometabolic Dysregulation (2014) (0)
- 776-6 Myocardial Adenylyl Cyclase Activity in an Animal Model of Dilated Cardiomyopathy Treated Chronically with the Non-Selective β-blocker Carteolol (1995) (0)
- Abstract 10631: Exosome-Encapsulated Adeno-Associated Viruses as a Novel Cardiotropic Vector for Gene Therapy in Heart Failure (2021) (0)
- Abstract 229: Increased Afterload Following Myocardial Infarction Promotes Conduction-dependent Arrhythmias That are Unmasked by Hypokalemia (2016) (0)
- Regulation of cardiac function in human heart failure (1991) (0)
- Expression of cardiac specific genes and functional testing of engineered cardiac tissues (2011) (0)
- zDHHC5 expression is increased in cardiac hypertrophy and reduced in heart failure but this does not correlate with changes in substrate palmitoylation (2022) (0)
- 3213 Unraveling the role of Phospholamban (PLN) in humans via the characterization of Induced Pluripotent Stem Cell (iPSC) Cardiomyocytes (CM) derived from carriers of a lethal PLN mutation (2019) (0)
- Structure-Based Design of Phospholamban Mutants for Gene Therapy (2010) (0)
- Abstract 12131: Mechanism of Hypokalemia-dependent Arrhythmias in a New Porcine Model of Advanced Heart Failure: Insights Into the Pathophysiology of Increased Afterload in Chronic Myocardial Infarction (2015) (0)
- SDF-1 induces TNF-mediated apoptosis in cardiac myocytes (2017) (0)
- 48. The Long-Term Effects of SERCA2a Overexpression in Large Animal Model of Heart Failure (2005) (0)
- Abstract 10315: The Role of Perivascular Fibrosis in Non-infarcted Myocardium in Congestive Heart Failure in Rats. (2010) (0)
- Abstract 3803: Myocardial CXCR4 Gene Transfer Negatively Modulates Cardiac Function Following Ischemia-Reperfusion Injury (2008) (0)
- Gene Therapy for Cardiovascular Diseases (2016) (0)
- Abstract 3864: MicroRNA-152 Represses SERCA2a and Contributes to the Impairment of Cardiomyocyte Contractile Function (2009) (0)
- GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIVATION DURING MYOCARDIAL INFARCTION REDUCES DIASTOLIC DYSFUNCTION IN PIGS (2012) (0)
- LV UNLOADING USING AN IMPELLA CP IMPROVES CORONARY FLOW AND INFARCT ZONE PERFUSION (2017) (0)
- Title Distinct roles of microRNA-1 and-499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes (2011) (0)
- The role of cAMP/PKA signaling enhancer Protein Phosphatase Inhibitor 1 (I‐1) in the control of Ca2+ cycling and signaling in VSMCs (2012) (0)
- 49. Evaluation of Catheter-Based Deliveries of 10um Gelatin Hydrogel Microsphere, a Novel Non-Viral Vehicle, in a Porcine Heart (2005) (0)
- Mesenchymal Stem Cells Enhance Contractile Function of Myocyte-Depleted Engineered Cardiac Tissues (2010) (0)
- P4352Gut microbiota and its dependent metabolite Trimethylamine N-oxide (TMAO) exacerbate adverse post-infarction left ventricular remodeling (2017) (0)
- CARDIAC SPECIFIC PROMOTER FOR MYOCARDIAL GENE TRANSFER (2003) (0)
- Abstract 222: CCN5 Overexpression Triggers Early Amplification Followed by Regression of Electrical Remodeling in a Pressure Overload Rat Model (2015) (0)
- Abstract 468: The Role of Ca2+/PKA Signaling Enhancer Protein Phosphatase Inhibitor 1 in the Control of Ca2+ Cycling and Signaling in VSMCs (2012) (0)
- CINE BALANCED STEADY-STATE FREE PRECESSION IS A RELIABLE ALTERNATIVE TO CONVENTIONAL T2-WEIGHTED IMAGING AND EVANS BLUE FOR THE CMR ASSESSMENT OF AREA AT RISK AFTER MYOCARDIAL INFARCTION (2013) (0)
- Pathogenesis of Heart Failure (2005) (0)
- GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIVATION REDUCES COMPENSATORY HYPERTROPHY AND LEFT VENTRICULAR REMODELING IN A PORCINE MODEL OF ISCHEMIA AND REPERFUSION (2012) (0)
- Basal Ca2+ Entry Controls NFAT Transcriptional Activity, Proliferation And Migration Of Human Vascular Smooth Muscle Cells (2009) (0)
- Abstract 15068: Expression of PW1 Identifies a New Candidate Cardiac Progenitor Population in the Adult Heart (2015) (0)
- Abstract 403: Tracking the Migration of Porcine Mesenchymal Stem Cells with the MRI Contrast Agent Ferex in an AAA Model (2012) (0)
- Abstract 14053: The Sphingosine 1-phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Post-infarction Left Ventricular Remodeling in a Porcine Model of Reperfused Myocardial Infarction (2013) (0)
- Recent Results of Cardiac Gene Therapy Clinical Trials (2016) (0)
- Abstract 256: mRNA-based Nanoparticles Are Highly Effective Agents For Cardiac Gene Therapy (2013) (0)
- Stem Cell Factor Gene Transfer Improves Cardiac Function After Myocardial Infarction in Swine Ishikawa et al: SCF Gene Therapy Improves Cardiac Function (2014) (0)
- Abstract 20347: Does Electrophysiological Toxicity Limit the Therapeutic Window of Serca2a Gene Therapy? (2014) (0)
- Engineering micro-alignments of 2- and 3-D hESC-derived ventricular tissues to reproduce anisotropic properties of the native heart: an accurate arrhythmias model for cardiotoxicity screening (2011) (0)
- Abstract 312: STIM1 And The Development Of Pressure-overload Induced Cardiac Hypertrophy In Rodents (2013) (0)
- Abstract 15794: Glucagon-Like Peptide-1 Receptor Activation Improves Systolic LV Function and LV Mechanics in a Porcine Model of Ischemia and Reperfusion (2012) (0)
- Labeling of Mesenchymal Stem Cells with Gadolinium Using Biodegradable Gelatin as a Transfection Agent (2005) (0)
- P.314Pharmacological activation of SERCA2a SUMOylation improves cardiac function and pathology in models of Duchenne muscular dystrophy (2019) (0)
- Abstract 326: FTO-mediated mRNA Demethylation Regulates Cardiac Contractile Protein Expression and Function (2019) (0)
- INCREASED EXPRESSION OF ADIPOKINE–RESISTIN EXPRESSION IN LIPID–RICH ATHEROMATOUS PLAQUES WHEN COMPARED TO LIPID POOR–FIBROTIC PLAQUES IN HUMAN ATHEROSCLEROSIS–IMPLICATION IN ACCELERATED ATHEROSCLEROTIC LESION PROGRESSION (2013) (0)
- Abstract 382: p300 Mediated Acetylation of the Cardiac Calcium Pump Reduces Its Activity and Contributes to Cardiac Dysfunction (2017) (0)
- Abstract 2732: Stabilisation of SR Leak in Heart Failure After SERCA2a Gene Therapy (2009) (0)
- Results of a Pre-Clinical Trial of Periostin Peptide in Myocardial Infarction (2009) (0)
- Abstract 5778: Protein Phosphatase 1 Signalling Pathway is Involved in the Control of Vascular Smooth Muscle Cells Proliferation (2009) (0)
- Abstract MP165: Exosome-mediated Encapsulation Alters AAV Antigenicity and Infectivity: Implications for Gene Delivery in the Heart (2020) (0)
- Canadian Journal of Cardiology Symposium Review Targeted Gene Therapy for the Treatment of Heart Failure (2011) (0)
- MYD88 IS INDISPENSABLE FOR PEPTIDOGLYCAN-ASSOCIATED LIPOPRPTEIN (PAL) -INDUCED DYSFUNCTION AND DEATH IN MOUSE CARDIOMYOCYTES.: 57 (2005) (0)
- Abstract 275: Electrophysiological Consequences of AAV9 mediated SERCA2a Gene Transfer to Normal Rat Myocardium (2014) (0)
- Abstract 16719: STIM1 Inhibits GSK3-Beta to Maintain Cardiac Hypertrophy in a Murine Pressure Overload Induced Heart Failure Model (2014) (0)
- Abstract 301: An m6A Demethylase, FTO Mediates Post-transcriptional mRNA Modifications to Regulate Cardiac and Cardiomyocyte Function (2018) (0)
- overexpression of phospholamban with use of adenovirus Functional alterations in adult rat myocytes after (2013) (0)
- Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes (2014) (0)
- Abstract 3231: Recombinant Periostin Peptide Improves Myocardial Function and Decreases Scar Size in a Preclinical Infarct Model (2009) (0)
- THE SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST FINGOLIMOD REDUCES ISCHEMIA-REPERFUSION INJURY BY DECREASING CARDIOMYOCYTE APOPTOSIS MEDIATED BY ACTIVATION OF THE RISK PATHWAY (2015) (0)
- Abstract 170: Exosomal AAV-mediated SERCA2a Gene Transfer Improves Cardiac Function in a Mouse Model of Heart Failure (2019) (0)
- , Claudia and VEGF Signaling α HIF-1 Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of (2014) (0)
- adenovirusof phospholamban with use of Functional alterations in adult rat myocytes after (2015) (0)
- THE ACTIVATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR BY FINGOLIMOD DURING MYOCARDIAL INFARCTION IMPROVES DIASTOLIC FUNCTION IN PIGS (2014) (0)
- cardiomyopathy in swine Development of a preclinical model of ischemic (2011) (0)
- ALTERNATIVELY SPLICED TISSUE FACTOR IS HIGHLY EXPRESSED IN COMPLEX HEMORRHAGIC CAROTID AND CLINICALLY UNSTABLE CORONARY PLAQUES (2013) (0)
- Inhibiting miR-25 Through Tough Decoy Gene Transfer Improves Calcium Handling and Cardiomyocyte Contractility in Aged MDX/UTRN KO Mice (2017) (0)
- 850. Efficiency of Six AAV Serotypes in Transducing Rat Myocardium In Vivo (2005) (0)
- Abstract 8142: By Virtue of Its Interaction with the {beta}2-adrenergic Receptor, CXCR4 Plays a Role in the Regulation of {beta}2-adrenergic Receptor Signaling Pathway Affecting Calcium and Contractility in Cardiac Myocytes (2011) (0)
- Abstract 447: The Role of Extracellular cAMP in the Pathogenesis of Pulmonary Arterial Hypertension (2018) (0)
- A role for calcium in resistin transcriptional activation in diabetic hearts (2018) (0)
- Abstract 14545: Glucagon-Like Peptide-1 Receptor Activation With Liraglutide During Acute Myocardial Infarction Improves Myocardial Salvage and Systolic Left Ventricular Function (2013) (0)
- Targeted Gene Therapy with RXFP1 Attenuates Myocardial Infarction and Preserves Left Ventricular Function in Mice (2018) (0)
- SERCA2A GENE TRANSFER INHIBITS PROGRESSIVE LV REMODELING IN POST MI CHRONIC HEART FAILURE (2014) (0)
- The heart of the matter (2011) (0)
- Ning Sun Dilated Cardiomyopathy Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial (2012) (0)
- 45. Adenoviral Gene Transfer of SERCA2a Restores Mechanical and Energetic Left-Ventricular Function in Spontaneously Diabetic Rats (2005) (0)
- Abstract 510: Extracellular cAMP as a Novel Therapeutic Strategy in Pulmonary Arterial Hypertension (2018) (0)
- Integrative Physiology Inhibition of PKC / With Ruboxistaurin Antagonizes Heart Failure in Pigs After Myocardial Infarction Injury Short Communication (2011) (0)
- The protein phosphatase 1 inhibitor-1: a potent “molecular inotrope” in cardiac function (2003) (0)
- Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies (2021) (0)
- Abstract O-2: The Role of Post-translational Modifications in SERCA2a-related Cardiac Dysfunction (2014) (0)
- Gene therapies for arrhythmias in heart failure (2014) (0)
- Social determinants of lifestyle and cardiovascular health in a minority community study for promotion of health (2018) (0)
- P932Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKC/Gal-3 signaling pathway attenuates adverse cardiac fibrosis, following myocardial infarction (2018) (0)
- Regression of cardiac hypertrophy by cyclic guanosine monophosphate-dependent protein kinase signaling are myocytes active sources or mere beneficiaries? (2010) (0)
- Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice (2017) (0)
- Abstract 185: Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Allows for Functional and Transcriptomic Insights Into Hereditary Dilated Cardiomyopathy Caused by Phospholamban Mutations (2017) (0)
- Gene therapy by SERCA2a for failing hearts in spontaneous type II DM model rats (2006) (0)
- Targeting Diabetes with a Novel Small Molecule Activator of Sarco/endoplasmic Reticulum Ca2+‐ATPase (SERCA) (2013) (0)
- Abstract 3174: Administration of Cyclin A2 by Gene Transfer Improves Cardiac Function in a Porcine Model of Myocardial Infarction (2009) (0)
- Abstract 652: Coronary Capillaries in Ischemic Congestive Heart Failure in Rats Exhibit Significant Morphological Disorder (2015) (0)
- Multi-Scale Biomechanics in a Marfan Syndrome Model of Dilated Cardiomyopathy (2014) (0)
- 1042. Tracking and Gene Expression Profile of Bone Marrow Mesenchymal Stem Cells Injected into Pig Myocardium by Magnetic Resonance Imaging and Laser-Capture Microdissection (2006) (0)
- Highlighting the Field of Cardiovascular Regenerative Medicine. (2018) (0)
- Abstract 10: Antifibrotic Effect of CCN5 in a Murine Model of Heart Failure (2012) (0)
- BACTERIAL PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN (PAL) INDUCES DYSFUNCTION IN CARDIOMYOCYTES THROUGH MYOCARDIAL TLR2 /MYD88.: 114 (2006) (0)
- Abstract 16618: Pre-Gadolinium Inversion-Recovery Sequence: A Novel and Reliable Magnetic Resonance Method for Assessing Area at Risk (2012) (0)
- Abstract 333: AAV9 Serca2a Gene Transfer Reverses Some but Not All Electrophysiological Deficits in a Chronic Model of Congestive Heart Failure (2015) (0)
- LV UNLOADING USING IMPELLA CP IMPROVES LA PRESSURE, FUNCTION, AND STIFFNESS IN ISCHEMIC PIG MODEL (2017) (0)
- Abstract 870: Cardiac Gene Therapy With Relaxin Receptor 1 Overexpression Protects Against Acute Myocardial Infarction and Associated Adverse Remodeling (2019) (0)
- Reproducibility of Three-Dimensional Vascular Ultrasound for the Detection and Quantification of Early Atherosclerosis: A FAMILIA Substudy (2018) (0)
- Cardiovascular Gene and Cell Therapy (2005) (0)
- SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2+ (2022) (0)
- Abstract 313: STIM1 Silencing Reverses Pressure-overload Induced Cardiac Hypertrophy In Mice (2013) (0)
- Gene Therapy for the Treatment of CPVT (2014) (0)
- Abstract 206: Stem Cell-derived Exosomes Induce Cardiac Repair via mRNA Modification (2016) (0)
- Ultra‐Compliant Indwelling Elastomer Balloons Improve Stability and Performance of Bioengineered Human Mini‐Hearts (2022) (0)
- Tracking Cell Therapy: Bioluminescence Lighting the Way⁎⁎Editorials published in JACC: Cardiovascular Imaging reflect the views of the authors and do not necessarily represent the views of JACC: Cardiovascular Imaging or the American College of Cardiology. (2012) (0)
- Integrative Cardiovascular Physiology and Pathophysiology Variability in coronary artery anatomy affects consistency of cardiac damage after myocardial infarction in mice (2017) (0)
- ECHOCARDIOGRAPHICAL ASSESSMENT OF POST-REPERFUSION WALL THICKENING ACCURATELY QUANTIFIES THE AREA AT RISK: AN EXPERIMENTAL PORCINE STUDY VALIDATED WITH MAGNETIC RESONANCE AND HISTOLOGY (2014) (0)
- Child Health Promotion in Underserved Communities: Primary Results From the Cluster Randomized FAMILIA Trial (2018) (0)
- Targeting the Serca-Plb Complex using FRET in Living Cells (2017) (0)
- Abstract 22: Identification of the Nature of Cardiac Resident c-kit+ Cells (2016) (0)
- Solution NMR structures of CBP bromodomain with small molecule of HBS (2011) (0)
- SERCA2a gene transfer reduces vascular smooth muscle cell proliferation in human arteries: A new target for restenosis? (2007) (0)
- Abstract 18097: PTEN Inhibition With VO-OHPIC Ameliorates Myocardial Ischemia-Reperfusion Injury Mediated by RISK Pathway Activation-Mediated Reduction of Apoptosis: An in vitro and in vivo Study (2016) (0)
- 1116. Gene Transfert of SERCA2a Inhibits Smooth Muscle Proliferation and Reduce Neointima Formation after Balloon Injury in the Rat (2005) (0)
- Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis (2020) (0)
- Abstract 259: Resistin Accelerates Fibroblast-Myofibroblast Differentiation and Induces Myocardial Fibrosis (2019) (0)
- 480 Role of the sarcoplasmic reticulum Ca2+ ATPase in the control of vascular smooth muscle cell proliferation (2003) (0)
- P.316Adeno-associated virus mediated SUMO1 overexpression improves cardiac disease phenotype in mouse models of Duchenne muscular dystrophy (2019) (0)
- In Situ Heart Isolation Featuring Closed Loop Recirculation: The Gold Standard for Optimum Cardiac Gene Transfer? (2017) (0)
- THE SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST FINGOLIMOD REDUCES MYOCARDIAL ISCHEMIA-REPERFUSION INJURY MEDIATED BY ACTIVATION OF AUTOPHAGY: AN IN VITRO AND IN VIVO STUDY (2015) (0)
- P4393Impella unloads left atrium and reduce atrial arrhythmogenicity (2017) (0)
- Abstract 5372: In Vivo Myocardial Distribution of Adult Stem Cells Immediately Following Intracoronary Delivery in a Swine Model of Myocardial Infarction (2008) (0)
- Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells (2018) (0)
- Abstract 18340: Alternatively Spliced Tissue Factor Promotes Atherosclerosis by Increasing Foam Cell Formation via LOX-1 and SR-A1 up-regulation (2015) (0)
- Abstract 16109: A Selective Cargo of Non-coding RNAs Mediate Therapeutic Potential of Human CD34+ Stem Cell-derived Exosomes (2015) (0)
- Left Ventricular Volume and Ejection Fraction Evaluation with Non-fluoroscopic Catheter-based Electromechanical Mapping (NOGA) and MRI (2009) (0)
- Abstract 2882: Directed Evolution of Cardiac Specific Adeno-Associated Vector Variants (2008) (0)
- Abstract 14976: Foxo3a Modulates Mitochondrial and Myocardial Function by Regulating Bnip3 Gene Expression in the Heart (2016) (0)
- MISE AU POINT/IN-DEPTH REVIEW GENE AND CELL THERAPY IN HEART FAILURE (2005) (0)
- Mesenchymal Stem Cells Potentiate Reparative Processes by Downregulation of Matrix Metalloproteinases 1, 3, and 9 in a Porcine Abdominal Aortic Aneurysm Model (2014) (0)
- 3444 Development of human engineered cardiac tissue (hECT)-based screening assay to explore cardiac contractile properties in response to pharmacological challenge with proarrhythmic drugs (2019) (0)
- Identification and Characterization of p300-Mediated Lysine Residues in Cardiac SERCA2a (2023) (0)
- STIM1 silencing prevents pressure‐overload induced cardiac hypertrophy in mice (2012) (0)
- Abstract 16942: Alternatively Spliced Tissue Factor promotes plaque progression, inflammation and angiogenesis in experimental atherosclerosis (2014) (0)
- Abstract 277: Lung Gene Transfer With Sarcoplasmic Reticulum Calcium ATPase Prevent Disease Progression in Pulmonary Arterial Hypertension (2018) (0)
- Abstract 2095: Cardiac-targeted RNA Interference Against STIM1 Using a Recombinant AAV9 Vector Limits the Progression of Heart Failure in Rats (2009) (0)
- SERCA2a Gene Therapy for Heart Failure (2016) (0)
- 2525 Development of human cell-based screening assays to detect subject-specific drug-response variability (2018) (0)
- P6516Impact of pulmonary hypertension on the left ventricular stiffness: Pressure-volume relationship study (2018) (0)
- Real-Time Imaging of Platelet-Rich Thrombi in Thick-Walled Blood Vessels Using Near-Infrared Fluorescence Light. (2006) (0)
- Cardionomics:anewintegrative approachforscreening cardiotoxicityofdrugcandidates (2009) (0)
- Abstract 584: FTO-Dependent m6A Regulates Cardiomyocyte and Cardiac Function During Remodeling and Repair (2018) (0)
- Abstract 38: A Decoy Peptide Selectively Inhibiting Dephosphorylation of Phospholamban (2012) (0)
- MYOCARDIAL OXYGENATION USING BLOOD LEVEL-OXYGEN DEPENDENT SEQUENCE IN MAGNETIC RESONANCE DETERMINES MYOCARDIAL ENERGETICS AND CAPILLARY DENSITY (2017) (0)
- Spectroscopic Design of Phospholamban Mutants to Treat Heart Failure (2010) (0)
- Abstract 130: The Diversity of Coronary Artery and Myocardial Infarction in Mice (2017) (0)
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What Schools Are Affiliated With Roger J. Hajjar?
Roger J. Hajjar is affiliated with the following schools: