Roger S. Goody
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English biochemist
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Roger S. Goodybiology Degrees
Biology
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Biochemistry
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Biology
Roger S. Goody's Degrees
- Bachelors Chemistry University of Oxford
Why Is Roger S. Goody Influential?
(Suggest an Edit or Addition)According to Wikipedia, Roger Sidney Goody is an English biochemist who served as director at the Max Planck Institute for Molecular Physiology in Dortmund from 1993 until 2013. Since 2013 he is Emeritus Director of the institute.
Roger S. Goody's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The original Michaelis constant: translation of the 1913 Michaelis-Menten paper. (2011) (1018)
- Refined crystal structure of the triphosphate conformation of H‐ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis. (1990) (1005)
- Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis (1990) (435)
- A toolkit and benchmark study for FRET-restrained high-precision structural modeling (2012) (377)
- Kinetics of interaction of nucleotides with nucleotide-free H-ras p21. (1990) (375)
- GTPase activity of Rab5 acts as a timer for endocytic membrane fusion (1996) (326)
- The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b (2010) (320)
- Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA 1 and BRCA 2 (2015) (318)
- The kinetic mechanism of Ran--nucleotide exchange catalyzed by RCC1. (1995) (243)
- Kinetic and structural analysis of the Mg(2+)-binding site of the guanine nucleotide-binding protein p21H-ras. (1993) (229)
- The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation. (1974) (227)
- Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide‐binding site. (1986) (217)
- Structure of the N6-adenine DNA methyltransferase M•TaqI in complex with DNA and a cofactor analog (2001) (213)
- Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase (2003) (212)
- Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras·GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins (1996) (203)
- Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase:primer/template complexes (2003) (188)
- RabGEFs are a major determinant for specific Rab membrane targeting (2013) (182)
- The interaction of bovine pancreatic deoxyribonuclease I and skeletal muscle actin. (1980) (175)
- Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors. (1995) (174)
- RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. (2009) (174)
- GrpE accelerates nucleotide exchange of the molecular chaperone DnaK with an associative displacement mechanism. (1997) (173)
- Structure of the Rab7:REP-1 Complex Insights into the Mechanism of Rab Prenylation and Choroideremia Disease (2004) (167)
- The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins. (1999) (166)
- Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate). (1976) (165)
- Synthetic inhibitors of adenylate kinases in the assays for ATPases and phosphokinases. (1975) (155)
- Molecular control of Rab activity by GEFs, GAPs and GDI (2017) (155)
- Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. (2009) (154)
- The structural and mechanistic basis for recycling of Rab proteins between membrane compartments (2005) (152)
- Proteins of contractile systems. (1976) (152)
- Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the β-Myosin Heavy Chain Gene (2007) (151)
- Thiophosphate analogs of nucleoside di- and triphosphates (1971) (150)
- Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention. (1990) (144)
- Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC. (1997) (133)
- The bottleneck in AZT activation (1997) (131)
- Transient kinetic studies on the interaction of Ras and the Ras-binding domain of c-Raf-1 reveal rapid equilibration of the complex. (1998) (131)
- Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy. (1997) (129)
- Site-selective protein immobilization by Staudinger ligation. (2006) (127)
- Kinetics of Interaction of Rab5 and Rab7 with Nucleotides and Magnesium Ions* (1996) (126)
- Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. (2003) (120)
- Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI‐mediated Rab recycling (2006) (114)
- Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. (2010) (112)
- Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins (2012) (112)
- Lipidated ras and rab peptides and proteins--synthesis, structure, and function. (2006) (111)
- Nucleotide exchange via local protein unfolding—structure of Rab8 in complex with MSS4 (2006) (109)
- Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators (2007) (105)
- Co-expression of the subunits of the heterodimer of HIV-1 reverse transcriptase in Escherichia coli. (1989) (103)
- GTPases involved in vesicular trafficking: structures and mechanisms. (2011) (103)
- Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins (2000) (99)
- A structural basis for Lowe syndrome caused by mutations in the Rab‐binding domain of OCRL1 (2011) (97)
- HIV-1 Nef membrane association depends on charge, curvature, composition and sequence. (2010) (97)
- Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation (1997) (96)
- High‐affinity binding of phosphatidylinositol 4‐phosphate by Legionella pneumophila DrrA (2010) (94)
- Oriented immobilization of farnesylated proteins by the thiol-ene reaction. (2010) (93)
- Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras. (1994) (91)
- p21 with a phenylalanine 28----leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties. (1991) (89)
- Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. (2000) (87)
- Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase. (1998) (86)
- Internal motions in myosin. (1979) (84)
- HIV-1 Reverse Transcriptase-Pseudoknot RNA Aptamer Interaction Has a Binding Affinity in the Low Picomolar Range Coupled with High Specificity* (2000) (84)
- Factors contributing to the inhibition of HIV reverse transcriptase by chain‐terminating nucleotides in vitro and in vivo (1991) (82)
- The signal recognition particle receptor of Escherichia coli (FtsY) has a nucleotide exchange factor built into the GTPase domain. (1997) (80)
- Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate. (1998) (80)
- Synthesis of protein-nucleic acid conjugates by expressed protein ligation. (2003) (80)
- Structural evidence that myosin heads may interact with two sites on F-actin (1982) (79)
- The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting (2014) (79)
- Excitatory signaling in bacterial probed by caged chemoeffectors. (1993) (79)
- α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner (2014) (79)
- Cross-bridge conformation as revealed by x-ray diffraction studies on insect flight muscles with ATP analogues. (1975) (78)
- Substrate and product structural requirements for binding of nucleotides to H-ras p21: the mechanism of discrimination between guanosine and adenosine nucleotides. (1995) (77)
- Protein LidA from Legionella is a Rab GTPase supereffector (2011) (77)
- Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases. (1990) (77)
- Is there a rate-limiting step before GTP cleavage by H-ras p21? (1991) (77)
- Refined model for primer/template binding by HIV-1 reverse transcriptase: pre-steady-state kinetic analyses of primer/template binding and nucleotide incorporation events distinguish between different binding modes depending on the nature of the nucleic acid substrate. (1999) (76)
- Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins. (2001) (76)
- The mechanism of guanosine nucleotide hydrolysis by p21 c-Ha-ras. The stereochemical course of the GTPase reaction. (1989) (75)
- The enzymatic synthesis of thiophosphate analogs of nucleotides. (1972) (75)
- Transient Kinetics of the Mg++ dependant ATP-ase of Myosin and its Proteolytic Subfragments (1973) (75)
- Kinetics of acto-S1 interaction as a guide to a model for the crossbridge cycle (1984) (74)
- Inhibition of human immunodeficiency virus type 1 reverse transcriptase dimerization using synthetic peptides derived from the connection domain. (1994) (73)
- Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids. (2006) (72)
- Preparation and characterization of nucleotide-free and metal ion-free p21 "apoprotein". (1987) (71)
- Exchange factors, effectors, GAPs and motor proteins: common thermodynamic and kinetic principles for different functions (2002) (71)
- Biochemical and biological consequences of changing the specificity of p21ras from guanosine to xanthosine nucleotides. (1996) (69)
- Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases. (1996) (69)
- Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. (1998) (69)
- Direct targeting of Rab-GTPase-effector interactions. (2014) (68)
- A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein (2006) (67)
- Cross-bridges and the mechanism of muscle contraction. (1983) (67)
- Adenylylation: renaissance of a forgotten post-translational modification. (2011) (67)
- A New Potent HIV-1 Reverse Transcriptase Inhibitor (1999) (67)
- A highly efficient strategy for modification of proteins at the C terminus. (2010) (66)
- Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process. (1995) (64)
- Characterization of the ternary complex between Rab7, REP-1 and Rab geranylgeranyl transferase. (1999) (63)
- Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor (2012) (63)
- Exploiting the Substrate Tolerance of Farnesyltransferase for Site‐Selective Protein Derivatization (2007) (63)
- Synthesis of ATP from ADP and inorganic phosphate at the myosin-subfragment 1 active site. (1974) (62)
- Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66 (1997) (61)
- Guanine nucleotide exchange factors operate by a simple allosteric competitive mechanism. (2005) (61)
- Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB (2013) (61)
- Total chemical synthesis of a functional interacting protein pair: The protooncogene H-Ras and the Ras-binding domain of its effector c-Raf1 (2003) (60)
- Viral resistance to the thiazolo-iso-indolinones, a new class of nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase (1993) (60)
- Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis. (1989) (60)
- The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociation (2013) (59)
- Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation* (1999) (59)
- Sec2 is a highly efficient exchange factor for the Rab protein Sec4. (2007) (58)
- The binding constant of ATP to myosin S1 fragment. (1977) (57)
- Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail (2012) (56)
- Kinetics of the Interaction of Translation Factor SelB fromEscherichia coli with Guanosine Nucleotides and Selenocysteine Insertion Sequence RNA* (2000) (56)
- Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase. (2016) (56)
- Interaction of fluorescently labeled dideoxynucleotides with HIV-1 reverse transcriptase. (1991) (55)
- RNase H activity of HIV reverse transcriptases is confined exclusively to the dimeric forms (1992) (55)
- X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp. (1995) (54)
- Synthesis of fluorescently labeled mono- and diprenylated Rab7 GTPase. (2004) (54)
- Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB* (2013) (54)
- Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of HIV-1 reverse transcriptase revealed by site-directed spin labelling. (2000) (54)
- Affinity of guanine nucleotide binding proteins for their ligands: facts and artefacts. (1991) (53)
- Rab GTPase Prenylation Hierarchy and Its Potential Role in Choroideremia Disease (2013) (53)
- Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. (2000) (53)
- Intein-mediated synthesis of geranylgeranylated Rab7 protein in vitro. (2002) (53)
- bMERB domains are bivalent Rab8 family effectors evolved by gene duplication (2016) (49)
- Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation (2008) (49)
- Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo. (2017) (49)
- Understanding and Exploiting Protein Prenyltransferases (2010) (48)
- Double Prenylation by RabGGTase Can Proceed without Dissociation of the Mono-prenylated Intermediate* 210 (2001) (48)
- Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains* (2009) (47)
- Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II. (2001) (47)
- Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport (2017) (47)
- Effects of ATP analogs on the low-angle X-ray diffraction Pattern of insect flight muscle (1973) (45)
- A Structural Model of the GDP Dissociation Inhibitor Rab Membrane Extraction Mechanism* (2008) (45)
- Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase. (2012) (45)
- Time-resolved cryo-electron microscopic study of the dissociation of actomyosin induced by photolysis of photolabile nucleotides. (1991) (44)
- X-ray titration of binding of β, γ-imido-ATP to myosin in insect flight muscle (1976) (44)
- Pre-steady-state kinetic characterization of RNA-primed initiation of transcription by HIV-1 reverse transcriptase and analysis of the transition to a processive DNA-primed polymerization mode. (1998) (44)
- Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI* (2012) (44)
- Characterisation of the metal-ion-GDP complex at the active sites of transforming and nontransforming p21 proteins by observation of the 17O-Mn superhyperfine coupling and by kinetic methods. (1987) (43)
- 4'-Thio-oligo-beta-D-ribonucleotides: synthesis of beta-4'-thio-oligouridylates, nuclease resistance, base pairing properties, and interaction with HIV-1 reverse transcriptase. (1993) (42)
- One-pot dual-labeling of a protein by two chemoselective reactions. (2011) (42)
- Direct readout of protein-protein interactions by mass spectrometry from protein-DNA microarrays. (2005) (41)
- Structural mapping of catalytic site with respect to alpha-subunit and noncatalytic site in yeast mitochondrial F1-ATPase using fluorescence resonance energy transfer. (1993) (41)
- Evaluation of human immunodeficiency virus type 1 reverse transcriptase primer tRNA binding by fluorescence spectroscopy: specificity and comparison to primer/template binding. (1996) (41)
- Binding of myosin subfragment 1 to glycerinated insect flight muscle in the rigor state. (1985) (39)
- Characterization of the dimerization process of HIV‐1 reverse transcriptase heterodimer using intrinsic protein fluorescence (1993) (38)
- Kinetics of interaction of HIV reverse transcriptase with primer/template. (1993) (38)
- Interaction of guanosine nucleotides and their analogs with elongation factor Tu from Thermus thermophilus. (1995) (38)
- Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues. (1989) (38)
- Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases. (2002) (37)
- Combining Chemical and Biological Techniques to Produce Modified Proteins (2002) (36)
- Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation* (2009) (36)
- Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II. (2000) (35)
- Studies on the structure and mechanism of H-ras p21. (1992) (35)
- A generic building block for C- and N-terminal protein-labeling and protein-immobilization. (2006) (35)
- Semi‐synthetic Rab proteins as tools for studying intermolecular interactions (2000) (34)
- Phosphoisoprenoids Modulate Association of Rab Geranylgeranyltransferase with REP-1* (2001) (34)
- High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis. (2000) (34)
- Monitoring the real-time kinetics of the hydrolysis reaction of guanine nucleotide-binding proteins (2005) (34)
- Selective spin diffusion. A novel method for studying motional properties of biopolymers in solution (1978) (34)
- Modulation of small GTPases by Legionella. (2013) (33)
- Triggering methods in crystallographic enzyme kinetics. (1997) (33)
- Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy (2013) (33)
- Probing protein function by chemical modification (2010) (32)
- Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases. (1995) (32)
- Development of selective, potent RabGGTase inhibitors. (2012) (32)
- Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding. (2008) (32)
- Stereochemical aspects of the interaction of myosin and actomyosin with nucleotides (1980) (32)
- Characterization of Enzymes from Legionella pneumophila Involved in Reversible Adenylylation of Rab1 Protein* (2012) (31)
- Structure-function relationships of HIV-1 reverse transcriptase determined using monoclonal antibodies. (1992) (30)
- Covalent coercion by Legionella pneumophila. (2011) (30)
- Expression of the heterodimeric form of human immunodeficiency virus type 2 reverse transcriptase in Escherichia coli and characterization of the enzyme. (1991) (30)
- Nucleosides. 68. Synthetic studies on nucleoside antibiotics. 5. 4-amino-2,3-unsaturated sugars related to the carbohydrate moiety of blasticidin S. (1970) (28)
- KRasG12C inhibitors in clinical trials: a short historical perspective† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00096e (2020) (28)
- Moderate discrimination of REP‐1 between Rab7⋅GDP and Rab7⋅GTP arises from a difference of an order of magnitude in dissociation rates 1 (1998) (27)
- Kinetics of nucleotide and metal ion interaction with G-actin. (1988) (27)
- Synthesis of functionalized rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligation. (2005) (27)
- InCa-SiteFinder: a method for structure-based prediction of inositol and carbohydrate binding sites on proteins. (2009) (26)
- Crystal structure of the Rab binding domain of OCRL1 in complex with Rab8 and functional implications of the OCRL1/Rab8 module for Lowe syndrome (2012) (26)
- Interface Peptides as Structure-based Human Immunodeficiency Virus Reverse Transcriptase Inhibitors (*) (1995) (26)
- Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity (2017) (26)
- A newly designed microspectrofluorometer for kinetic studies on protein crystals in combination with x-ray diffraction. (2006) (25)
- Synthetic human tRNA(UUULys3) and natural bovine tRNA(UUULys3) interact with HIV-1 reverse transcriptase and serve as specific primers for retroviral cDNA synthesis. (1992) (25)
- Fluorescently labelled guanine nucleotide binding proteins to analyse elementary steps of GAP-catalysed reactions. (2002) (25)
- Template. Phosphorothioate oligonucleotides duplexes as inhibitors of HIV-1 reverse transcriptase. (1992) (24)
- A Protein Fluorescence Amplifier: Continuous Fluorometric Assay for Rab Geranylgeranyltransferase (2006) (24)
- Identification and characterisation of novel Mss4-binding Rab GTPases (2011) (24)
- Functional Immobilization of the Small GTPase Rab6A on DNA–Gold Nanoparticles by Using a Site‐Specifically Attached Poly(ethylene glycol) Linker and Thiol Place‐Exchange Reaction (2007) (23)
- Co-ordinated electron microscopy and X-ray studies of glycerinated insect flight muscle. I. X-ray diffraction monitoring during preparation for electron microscopy of muscle fibres fixed in rigor, in ATP and in AMPPNP (1983) (23)
- The complex of actin and deoxyribonuclease I as a model system to study the interactions of nucleotides, cations and cytochalasin D with monomeric actin. (1989) (23)
- Thiophosphate-analogues and 1-N-oxides of ATP and ADP in mitochondrial translocation and phosphoryl-transfer reactions. (1973) (23)
- Efficient synthesis and applications of peptides containing adenylylated tyrosine residues. (2011) (23)
- The interaction of HIV-1 Tat(32-72) with its target RNA: a fluorescence and nuclear magnetic resonance study. (1997) (23)
- Light as a trigger for time-resolved structural experiments on muscle, lipids, p21 and bacteriorhodopsin (1991) (23)
- The structure of the EF-Tu . GDP . Me2+ complex. (1982) (23)
- Structure-guided development of selective RabGGTase inhibitors. (2011) (22)
- Locking GTPases covalently in their functional states (2015) (22)
- The missing link in the muscle cross-bridge cycle (2003) (22)
- Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli. (2009) (22)
- Co-ordinated electron microscopy and X-ray studies of glycerinated insect flight muscle. II. Electron microscopy and image reconstruction of muscle fibres fixed in rigor, in ATP and in AMPPNP (1983) (21)
- Stereochemistry of the elongation factor Tu X GTP complex. (1983) (21)
- A new high sensitivity 19F probe for labeling cysteine groups of proteins (1992) (21)
- Fluorescence methods for monitoring interactions of Rab proteins with nucleotides, Rab escort protein, and geranylgeranyltransferase. (2001) (21)
- Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points. (1994) (20)
- Information Theory-Based Scoring Function for the Structure-Based Prediction of Protein-Ligand Binding Affinity (2008) (20)
- Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates. (2002) (20)
- Chemo-Enzymatic Synthesis of Fluorescent Rab 7 Proteins: Tools to Study Vesicular Trafficking in Cells. (1999) (20)
- A sensitive fluorescence monitor for the detection of activated Ras: total chemical synthesis of site-specifically labeled Ras binding domain of c-Raf1 immobilized on a surface. (2001) (19)
- Time-Resolved Structural Studies on Insect Flight Muscle after Photolysis of Caged-ATP. (1986) (19)
- Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors. (2009) (19)
- Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex. (2008) (19)
- The ternary complex formed between actin, myosin subfragment 1 and ATP (β, γ‐NH) (1978) (19)
- Structural investigations of the Mg.ATP complex at the active site of porcine adenylate kinase using phosphorothioate analogs and electron paramagnetic resonance of Mn(II) with chiral 17O-labelled ATP analogs. (1983) (19)
- [13] DNA sequencing using α-thiodeoxynucleotides (1987) (19)
- Lasers and flashlamps in research on the mechanism of muscle contraction (1989) (18)
- An analysis of the structure of insect flight muscle in rigor and in the presence of ATP (β, γ−NH) (1980) (18)
- C‐Terminal Fluorescence Labeling of Proteins for Interaction Studies on the Single‐Molecule Level (2006) (18)
- The time course of changes in the equatorial diffraction patterns from different muscle types on photolysis of caged-ATP. (1988) (18)
- The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members (2020) (17)
- The versatile Legionella effector protein DrrA (2011) (17)
- Analysis of the polymerization kinetics of homodimeric EIAV p51/51 reverse transcriptase implies the formation of a polymerase active site identical to heterodimeric EIAV p66/51 reverse transcriptase. (1998) (17)
- Direct immobilization of oxyamine-modified proteins from cell lysates. (2012) (17)
- Dynamic X-ray diffraction measurements following photolytic relaxation and activation of skinned rabbit psoas fibres. (1991) (17)
- Relaxation of chemically skinned guinea pig taenia coli smooth muscle from rigor by photolytic release of adenosine-5′-triphosphate (1987) (17)
- Kinetic and Structural Analysis of the Mg 2 +-binding Site of the Guanine Nucleotide-binding Protein p 21 Hras (2009) (16)
- The structure of the N-terminal domain of the Legionella protein SidC. (2014) (16)
- How not to do kinetics: examples involving GTPases and guanine nucleotide exchange factors (2014) (16)
- Simple synthesis and separation of the diastereomers of α-thio analogs of ribo- and deoxyribo-di- and triphosphates (1986) (16)
- Lipidated Ras and Rab Peptides and Proteins — Synthesis, Structure, and Function (2007) (16)
- A genetically encodable microtag for chemo-enzymatic derivatization and purification of recombinant proteins. (2005) (16)
- In vitro assembly, purification, and crystallization of the rab geranylgeranyl transferase:substrate complex. (2002) (15)
- Intramolecular interactions in protein tyrosine phosphatase RPTPmu: kinetic evidence. (2001) (15)
- Design, total chemical synthesis, and binding properties of a [Leu-91-N1-methyl-7-azaTrp]Ras-binding domain of c-Raf-1. (1999) (15)
- The significance of the free energy of hydrolysis of GTP for signal-transducing and regulatory GTPases. (2002) (15)
- Study of the substrate-binding properties of bovine liver adenosine kinase and inhibition by fluorescent nucleoside analogues. (1997) (15)
- Three-dimensional structure and properties of wild-type and mutant H-ras-encoded p21. (1993) (15)
- Nucleotide and AP5A complexes of porcine adenylate kinase: A 1H and 19F NMR study. (1989) (15)
- 31P NMR spectra of thiophosphate analogues of guanosine nucleotides (1980) (15)
- Intrinsic tryptophan fluorescence of bovine liver adenosine kinase, characterization of ligand binding sites and conformational changes. (1994) (15)
- Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases. (2005) (14)
- Hydrostatic pressure affects the conformational equilibrium of Salmonella typhimurium tryptophan synthase. (2005) (14)
- Escherichia coli isocitrate dehydrogenase kinase/phosphatase. Overproduction and kinetics of interaction with its substrates by using intrinsic fluorescence and fluorescent nucleotide analogues. (1996) (14)
- Pressure modulation of Ras-membrane interactions and intervesicle transfer. (2013) (14)
- Time-resolved crystallography on H-ras p21 (1992) (14)
- Kinetics of adenosine 5'-triphosphate and adenosine 5'-diphosphate interaction with G-actin. (1988) (14)
- Guanosine thiophosphate derivatives as substrate analogues for phosphoenolpyruvate carboxykinase. (1985) (14)
- Flexible and General Synthesis of Functionalized Phosphoisoprenoids for the Study of Prenylation in vivo and in vitro (2012) (14)
- Reaction mechanism of adenylyltransferase DrrA from Legionella pneumophila elucidated by time-resolved fourier transform infrared spectroscopy. (2014) (13)
- A pull-down procedure for the identification of unknown GEFs for small GTPases (2016) (13)
- The structure of S1-decorated actin filaments calculated from x-ray diffraction data with phases derived from electron micrographs. (1982) (13)
- Multivalency in Rab effector interactions (2017) (13)
- Towards a molecular mechanism for the crossbridge cycle. (1988) (13)
- A New Method of DNA Sequencing Using Deoxynucleoside α-Thiotriphosphates (1986) (13)
- The interpretation of X-ray diffraction from glycerinated flight muscle fibre bundles: new theoretical and experimental approaches (1977) (12)
- Nucleotide Hydrolysis-dependent Conformational Changes in p21 ras as Studied Using ESR Spectroscopy* (1997) (12)
- Mutant-Specific Targeting of Ras G12C Activity by Covalently Reacting Small Molecules. (2019) (12)
- Antisense principle or ribozyme action? (1994) (12)
- Crystallization and preliminary X-ray diffraction analysis of monoprenylated Rab7 GTPase in complex with Rab escort protein 1. (2003) (12)
- Structural and Mechanistic Aspects of the GTPase Reaction of H-ras p21 (1993) (12)
- Protein–DNA Arrays as Tools for Detection of Protein–Protein Interactions by Mass Spectrometry (2013) (11)
- Kinetic and thermodynamic properties of the ternary complex between F-actin, myosin subfragment 1 and adenosine 5'-[beta, gamma-imido]triphosphate. (1982) (11)
- Key determinants of Rab specificity. (2008) (11)
- How G proteins turn off (1994) (11)
- An investigation of the cross-bridge cycle using ATP analogues and low-angle X-ray diffraction from glycerinated fibres of insect flight muscle (1976) (11)
- On the structure of the myosin‐ADP‐Mg complex (1981) (11)
- Electron-paramagnetic-resonance studies of manganese(II) complexes with elongation factor Tu from Bacillus stearothermophilus. Observation of a GTP hydrolysis intermediate state complex. (1984) (10)
- Specific localization of Rabs at intracellular membranes. (2012) (10)
- Kinetic and Thermodynamic Properties of the Ternary Complex between F-actin, Myosin Subfragment 1 and Adenosine 5′-[β,γ-imido]triphosphate (2005) (10)
- Review: Ras GTPases and myosin: Qualitative conservation and quantitative diversification in signal and energy transduction (2016) (10)
- The structure of insect flight muscle in the presence of AMPPNP (1987) (10)
- The preparation of thiophosphate analogs of GDP and their interaction with EF‐Tu (1979) (10)
- Equine infectious anemia virus transactivator is a homeodomain-type protein. (1998) (9)
- A simple and rapid method for the synthesis of nucleoside 5'-monophosphates enriched with 17O or 18O on the phosphate group. (1982) (9)
- Crystallization and preliminary X‐ray analysis of UMP/CMP‐kinase from Dictyostelium discoideum with the specific bisubstrate inhibitor P1‐(adenosine 5′)‐P5‐(uridine 5′)‐pentaphosphate (UP5A) (1995) (9)
- The permanganate oxidation of cytosine derivatives (1971) (9)
- Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases [Erratum to document cited in CA113(9):73603k] (1990) (8)
- Improving AZT efficacy (1998) (8)
- Functional nucleotide-binding domain in the F0F1-ATPsynthase alpha subunit from the yeast Schizosaccharomyces pombe. (1993) (8)
- Use of caged nucleotides to characterize unstable intermediates by X-ray crystallography. (1998) (8)
- The use of some novel X-ray diffraction techniques to study the effect of nucleotides on cross-bridges in insect flight muscle (1979) (8)
- Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition. (2005) (8)
- In vitro semisynthesis and applications of C-terminally modified rab proteins. (2004) (7)
- Crystallization and preliminary X-ray structure analysis of thermally unstable p21(H-ras) guanosine complexes. (1994) (7)
- New N-2-labelled fluorescent derivatives of guanosine nucleotides and their interaction with GTP-binding proteins (1999) (7)
- The interaction of myosine S1 with phosphorothioates of ADP: an 18O exchange study by 31P NMR. (1981) (7)
- Synthetic analogues of polynucleotides. Part VII. Further syntheses of 5′-O-acryloylnucleosides and copolymers of these with other acryloyl compounds (1971) (7)
- What to do if there is no signal: using competition experiments to determine binding parameters (2003) (7)
- Synthesis of 2′-Iodo- and 2′-Bromo-ATP and GTP Analogues as Potential Phasing Tools for X-ray Crystallography (1999) (7)
- The crystal and molecular structure of tetrapyridine bis(diethylphosphorothioato)magnesium(II), a model substance for polynucleotide phosphorothioates (1973) (7)
- The nature of the actin cross-bridge interaction. (1984) (6)
- Semisynthesis of H‐Ras with a glutamic acid methylester at position 61 (2008) (6)
- Cross-linked long-pitch actin dimer forms stoichiometric complexes with gelsolin segment 1 and/or deoxyribonuclease I that nonproductively interact with myosin subfragment 1. (2008) (6)
- Synchrotron Radiation Studies on Insect Flight Muscle (1988) (6)
- Characterization of fluorescence-labeled DNA by time-resolved fluorescence spectroscopy (1991) (6)
- Application of protein semisynthesis for the construction of functionalized posttranslationally modified rab GTPases. (2005) (6)
- Stereochemistry and lifetime of the GTP hydrolysis intermediate at the active site of elongation factor Tu from Bacillus stearothermophilus as inferred from the 17O-55Mn superhyperfine interaction. (1990) (6)
- Time-resolved X-ray diffraction studies on stretch-activated insect flight muscle (1991) (5)
- The use of nucleotide phosphorothioate diastereomers to define the structure of metal-nucleotide bound to GTP-AMP and ATP-AMP phosphotransferases from beef-heart mitochondria. (1984) (5)
- Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase. (2001) (5)
- X-ray titration of binding of beta, gamma-imido-ATP to myosin in insect flight muscle. (1976) (4)
- The use of modified nucleotides in studies of translocationand oxidative phosphorylation in rat liver mitochondria (1973) (4)
- Assays for Nucleotide Competitive Reversible and Irreversible Inhibitors of Ras GTPases. (2018) (4)
- Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria (2011) (4)
- Rapid determination of the affinity of 28- and 14-mer phosphorothioate oligonucleotides for HIV-1 reverse transcriptase by fluorescence spectroscopy. (1993) (4)
- Rapid production of functionalized recombinant proteins: marrying ligation independent cloning and in vitro protein ligation. (2006) (4)
- Rational drug design and HIV: Hopes and limitations (1995) (4)
- An improved separation of diastereomers of nucleoside phosphorothioates using reversed-phase high-performance liquid chromatography (1983) (4)
- 2′Halo‐ATP and ‐GTP analogues: Rational phasing tools for protein crystallography (2008) (4)
- Some N-6 acylated cytosines (1967) (4)
- [Elimination and excretion of adenylate kinases following cell damage]. (1975) (4)
- The influence of metal ion complexation on 31P-NMR parameters of phosphorothioates of guanosine nucleotides (1984) (4)
- Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae (2018) (4)
- The ternary complex formed between actin, myosin subfragment 1 and ATP (beta, gamma-NH). (1978) (3)
- Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid (2003) (3)
- DNA sequencing using alpha-thiodeoxynucleotides. (1987) (3)
- Organization and function of the Rab prenylation and recycling machinery (2011) (3)
- Rapid Synthesis of 2′ and 3′ Fluorinated Nucleotides and Their Use in 19F-NMR-Spectroscopy of Nucleotide-Binding Enzymes (1989) (3)
- Dynamic structural investigations on Lethocerus flight muscle following mechanical and biochemical perturbations (1986) (3)
- Synthesis and Biological Applications of 2′,3′-Dideoxynucleoside-5′-O-(α-thio)Triphosphates (1989) (3)
- 31P NMR studies on ATP.Mg2+p21−nucleotide complexes. Chemical shifts, rate and equilibrium constants (1986) (3)
- α, ω-Diadenosine Polyphosphates, a New Class of Substances, and ADP-Methylester Inhibit Platelet Aggregation and the Release Reaction (1975) (2)
- Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes (vol 6, pg 534, 2010) (2010) (2)
- A DFDL UV picosecond fluorescence spectrometer: Application to aqueous solutions of peptides and nucleotide dye conjugates (1989) (2)
- Towards Elucidation of the Phenazine Biosynthesis Pathway with the Structural and Functional Analysis of the enzymes PhzA, PhzB, PhzG and BcepA (2006) (2)
- The Role of the Cytoskeleton in Transport and Release of Insulin-Containing Granules by Pancreatic β-Cells (2011) (2)
- Structural investigations on HIV-1 RT using single pair fluorescence resonance energy transfer (2002) (2)
- structure of Rab8 in complex with MSS4 (2006) (2)
- Nucleosides. LXVI. Synthetic studies on nucleoside antibiotics. 4. Synthesis of methyl 4-amino-2,3,4-trideoxy-alpha-D-erythro-hex-2-enopyranosiduronic acid, the carbohydrate moiety of blasticidin S. (1970) (2)
- [Mitochondrial translocation of thiophosphate analogues of adenine nucleotides]. (1972) (2)
- Intermediates in the Guanine Nucleotide Exchange Reaction of Rab 8 Catalyzed by Rabin 8 / GRAB (2013) (2)
- Cell‐free synthesis of the Ras‐binding domain of c‐Raf‐1: binding studies to fluorescently labelled H‐Ras (1999) (2)
- Information Theory‐Based Scoring Function for the Structure‐Based Prediction of Protein—Ligand Binding Affinity. (2009) (2)
- Synthesis of 2′,3′,5′-trideoxyuridine-5′-methylphosphonic Acid and its Diphosphate Derivative. Study of the Interaction with HIV-1 reverse Transcriptase (1994) (2)
- A two-way structure (1996) (2)
- Prenylation of RabGTPases, Their Delivery to Membranes, and Rab Recycling (2014) (2)
- 31P-NMR studies on ATP X Mg2+, p21 X nucleotide, and adenylate kinase X nucleotide complexes. Chemical shifts, rate and equilibrium constants. (1986) (2)
- Cryo-electron microscopy of vitrified muscle samples. (1992) (2)
- How bacteria choose phosphate. (2013) (2)
- Studies on the Interaction between HIV-1 Reverse Transcriptase and Templateoligo α-Thymidylate Duplexes (1991) (2)
- Intein‐Mediated Construction of a Library of Fluorescent Rab GTPase Probes (2011) (2)
- Semisynthesis of human thymidine monophosphate kinase. (2010) (2)
- The molecular basis of contractility. II. (1974) (1)
- LIGAND BINDING PROPERTIES OF BOVINE LIVER ADENOSINE KINASE (1995) (1)
- Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector (2022) (1)
- The Pseudo‐Natural Product Rhonin Targets RHOGDI (2022) (1)
- Correction: A new potent HIV-1 reverse transcriptase inhibitor: A synthetic peptide derived from the interface subunit domains. (2019) (1)
- Preparation and Characterization of Nucleotide-free and Metal Ion- (1987) (1)
- Inhibition of Rab Prenylation (2011) (1)
- Structure of the Actin/Tropomyosin/Myosin Rigor Complex as Revealed by Cryo-Electron Microscopy (2012) (1)
- The molecular basis of contractility Part II (2005) (1)
- Effects of hydrostatic pressure on the conformational equilibrium of tryptophan synthase from Salmonella typhimurium (2010) (1)
- Identification of RabGGTase inhibitors and mechanistic studies of Rab GTPase prenylation and recyling using fluorescent sensors (2008) (1)
- CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION (1999) (1)
- Mechanism of substrate binding and product release by geranylgeranyl-transferase type II (2000) (1)
- The European Molecular Biology Organization/Muscular Dystrophy Association Workshop on the Structure of Actin and Myosin and the Mechanism of their Interaction, Alpbach, March 1983 (1983) (1)
- A new method of DNA sequencing using deoxynucleoside alpha-thiotriphosphates. (1986) (1)
- Inhibition of Myosin ATPase with a Disulfide Analog of ATP (1973) (1)
- [31P Nuclear magnetic resonance spectra]. (1984) (1)
- Kinetic and Structural Analysis of the Mg 2 +-binding Site of the Guanine Nucleotide-binding Protein p 2 lH + = * (2001) (1)
- Biochemical and crystallographic characterization of a complex of cHaras p 21 and caged GTP with flash photolysis ( time-resolved structure ) (1)
- Domain specific isotope labelling of membrane proteins - NMR and FTIR spectroscopy of SRII/HtrII complexes from Natronobacterium pharaonis (2005) (1)
- Crystal structure of the N-terminal domain of the Legionella pneumophila protein SidC at 2.4A resolution (2014) (1)
- Time-Resolved FTIR-Studies of H-Ras P21 GTPase Activity (1994) (1)
- 18O-Exchange by Hydrolyzing Enzymes: An ab initio Calculation (1981) (1)
- Protein semi-synthesis and its application to studies of structure and function of GTPases (2005) (1)
- ADENINE-SPECIFIC METHYLTRANSFERASE M. TAQ I/DNA COMPLEX (2001) (1)
- 31P-NMR spectra of AP4 (1985) (1)
- The molecular basis of muscle contraction. (1983) (1)
- Crystal structure of human rab1b bound to GDP and BEF3 in complex with the GAP domain of TBC1D20 from homo sapiens (2013) (0)
- Crystal structure of the GEF and P4M domain of DrrA/SidM from Legionella pneumophila (2010) (0)
- FTase in complex with BMS analogue 11 (2012) (0)
- Signal transduction. How G proteins turn off. (1994) (0)
- Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate,a magnesium-ion and ALf3 (2001) (0)
- Combining Chemical and Biological Techniques to Produce Modified Proteins. (2010) (0)
- The molecular basis of contractility. I. (1974) (0)
- Development of approaches for the engineering of gene expression in the protozoa Leishmania tarentolae (2007) (0)
- CRYSTAL STRUCTURE OF THE YPT/RAB-GAP DOMAIN OF GYP1P (2001) (0)
- Characterization of Novel Inhibitors of Protein Prenyltransferases (2007) (0)
- Synthese of 2',3',5'−trideoxyuridine−5'−methylphosphonic acid and its diphosphate derivative. Study of interaction with HIV−1 Reverse Transcriptase (1994) (0)
- Functional Analysis of Host–Pathogen Posttranslational Modification Crosstalk of Rab Proteins (2014) (0)
- Structural studies on human RZZ and Cln3p (2014) (0)
- Structural and Biophysical Characterisation of the small GTPase Rab6a and its Effectors BicaudalD2, p150pglued and PIST (2006) (0)
- NMR Studies of the Nucleotide Binding−Sites of Adenylate Kinase (1991) (0)
- Crystal structure of GDP-bound Rab8:Rabin8 (2013) (0)
- Determinatton of Equilibrium and Kinetic Constants for the Interaction of GTPases with Nucleotides, Regulators and Effectors (2021) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32) (2009) (0)
- Crystal structure of thymidylate kinase fromSaccharomyces cerevisiaewith substrate bound (1996) (0)
- Crystal structure of GDP-bound Rab8:GRAB (2013) (0)
- Correlations between structural and chemical states of cross-bridges in muscle. (1983) (0)
- Abstracts of the XVIII European Conference on Muscle and Motility (1990) (0)
- A fluorescent in vivo protein‐prenylation assay (2006) (0)
- The Study of Rab GTPase Recycling Using Semi-synthetic Prenylated Proteins (2009) (0)
- Protein prenylation reactions as tools for site-specific protein labeling and identification of prenylation substrates (2009) (0)
- The structural and mechanistic basis of regulation of vesicular transport by Rab proteins (2009) (0)
- The molecular basis of contractility Part I (2005) (0)
- Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3 (2013) (0)
- The Interaction of Adenosine Triphosphate and its Analogs with Myosin and the Modification by Actin (1975) (0)
- STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K (1999) (0)
- Dynamics of DNA and HIV-1 reverse transcriptase-DNA complexes studied by four-dimensional single-molecule fluorescence spectroscopy (2000) (0)
- Structure of human Rab10 in complex with the bMERB domain of Mical-cL (2016) (0)
- Structure of the bMERB domain of Mical-3 (2016) (0)
- Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors (2022) (0)
- Engineered RabGGTase in complex with BMS analogue 12 (2012) (0)
- The preparation and properties of some cytosine derivatives. (1971) (0)
- Crystal structure of yeast Rab-GDI (2008) (0)
- Kinetic characterisation of microgram quantities of myosins using a novel flash photolysis apparatus (2002) (0)
- Cover Picture: Exploiting the Substrate Tolerance of Farnesyltransferase for Site‐Selective Protein Derivatization (ChemBioChem 4/2007) (2007) (0)
- Table of Contents (1990) (0)
- The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein (2004) (0)
- Motor proteins. A two-way structure. (1996) (0)
- Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP (2009) (0)
- Targeting REP:GGTase-II Interaction and Finding New Means to Predict the Protein:Ligand Interactions (2008) (0)
- The interpretation of X−ray diffraction from glycerinated flight muscle (1977) (0)
- Mutant human thymidylate kinase (F105Y) complexed with AZTMP and ADP (2001) (0)
- GPPNHP-Bound Rab7 (2004) (0)
- Single molecule imaging of the signaling activity of the epidermal growth factor receptor (2014) (0)
- Crystal structure of nucleotide-free Rab8:Rabin8 (2013) (0)
- Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL (2016) (0)
- Crystal structure of Rab8 in its active GppNHp-bound form (2013) (0)
- Mechanistic studies of Rab GTPase membrane targeting and cycling in cells (2017) (0)
- Engineered RabGGTase in complex with BMS analogue 16 (2012) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 9) (2009) (0)
- Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BMS3 and lipid substrate FPP (2011) (0)
- TheMagnesium Ion-Dependent Adenosine Triphosphatase ofMyosin TWO-STEPPROCESSESOF ADENOSINETRIPHOSPHATEASSOCIATIONAND ADENOSINE DIPHOSPHATEDISSOCIATION (1974) (0)
- Synthesis of the Ras-RBD Protein Pair (2001) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (2008) (0)
- Human thymidylate kinase complexed with AZTMP and ADP (2001) (0)
- Thioanalogues of Phosphate Esters and Phosphorylation Mechanisms (1974) (0)
- Nucleotide and AP5A Complexes of Porcine Adenylate Kinase: A 'H and 19F (1989) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS-analogue 14 (2011) (0)
- Tucker, J. et al. Expression of p21 proteins in Escherichia coli and stereochemistry of th nucleotide-binding site. EMBO J. 5, 1351-1358 (1986) (0)
- The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein (2004) (0)
- Crystal structure of Rab1b covalently modified with AMP at Y77 (2010) (0)
- FTase in complex with BMS analogue 16 (2012) (0)
- LidA from Legionella in complex with active Rab8a (2011) (0)
- Crystal structure of Ypt31 in complex with yeast Rab-GDI (2008) (0)
- Hydrostatic Pressure as a Structural and Mechanistic Probe of Tryptophan Synthase and Tryptophan Indole‐lyase (2006) (0)
- GTPase activity of RAB5 as a timer for endocytic membrane fusion (1996) (0)
- Crystal structure of the N-terminal domain of DrrA/SidM from Legionella pneumophila (2010) (0)
- GDP-Bound Rab7 (2004) (0)
- NMR investigations on myosin (1978) (0)
- Synchrotron radiation as a tool in muscle physiology (1982) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with di-prenylated peptide Ser-Cys(GG)-Ser-Cys(GG) derivated from Rab7 (2008) (0)
- Human thymidylate kinase complexed with AZTMP and APPNP (2001) (0)
- Structural and functional studies on the small GTPase Ypt7p and its interacting partners (2001) (0)
- Chemical genetic study of autophagy regulation (2015) (0)
- Reply to “Improving AZT efficacy” (1998) (0)
- Crystal structure of the Legionella pneumophila GAP domain of LepB (2013) (0)
- Human thymidylate kinase complexed with ADP, TDP and a magnesium-ion (2001) (0)
- Mutant human thymidylate kinase complexed with TMP and APPNP (2001) (0)
- Crystal structure of the longin domain of yeast Ykt6 (2008) (0)
- Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity (2017) (0)
- The three-dimensional structures of the G/2D mutant and of the native complex with the unceptide analog mant-GppNP (1992) (0)
- New N‐2‐Labelled Fluorescent Derivatives of Guanosine Nucleotides and Their Interaction with GTP‐Binding Proteins. (1999) (0)
- Genetically encoded conformational probes for small GTPase activity (2018) (0)
- Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP (2009) (0)
- FTase in complex with BMS analogue 12 (2012) (0)
- The influence of ionic strength upon relaxation from rigor induced by flash photolysis of caged-ATP in skinned murine skeletal muscle fibres (1995) (0)
- FTase in complex with BMS analogue 14 (2012) (0)
- United States Patent Siegert (2017) (0)
- Semi-synthesis and biological evaluation of prenylated Rab proteins (2004) (0)
- Structural studies of vesicular transport components (2001) (0)
- Wild type human thymidylate kinase complexed with AZTMP and ADP (2001) (0)
- THE GTPASE REACTION OF RAS (1997) (0)
- Functional Characterisation of the Muscle Giant Protein Obscurin (2004) (0)
- [Identification of a 2nd myosine configuration using ATP analogues]. (1972) (0)
- Simple Synthesis and Separation of the Diastereomers of α-Thio Analogs of Ribo- and Deoxyribo-di- and -triphosphates. (1986) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG) (2008) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 (2011) (0)
- Crystal structure of the human TBC1D20 RabGAP domain (2013) (0)
- Engineered RabGGTase in complex with BMS analogue 13 (2012) (0)
- New dynamic and structural dynamic investigations on insect flight muscle (1982) (0)
- The School of Hard Nox: Characterization of human Nox1 and cyclized Rab7 (2008) (0)
- Structural Studies of the Rab Prenylation Mechanism and of RabGGTase in Complex with Inhibitors (2008) (0)
- Crystal structure analysis of a fluorescent form of H-Ras p21 in complex with R-caged GTP (2006) (0)
- Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate and a magnesium-ion (2001) (0)
- Crystal structure of Sec4 in complex with Rab-GDI (2008) (0)
- Article in press-uncorrected proof Identification and characterisation of novel Mss 4-binding Rab GTPases (2011) (0)
- Alternative Substrate Für Argininkinase (2009) (0)
- Synthetic Peptides and Proteins to Elucidate Biological Function (2008) (0)
- Mutant human thymidylate kinase complexed with TMP and ADP (2001) (0)
- FTase in complex with BMS analogue 13 (2012) (0)
- Crystal structure of Ypt7 covalently modified with GDP (2014) (0)
- Crystal structure of Rab8 in its inactive GDP-bound form (2013) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 8) (2009) (0)
- The European Molecular Biology Organization Workshop on the Structure and Mechanism of Muscle, Alpbach, March 1980 (1980) (0)
- RabGGTase in complex with covalently bound Psoromic acid (2012) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with geranylgeranyl pyrophosphate (2008) (0)
- Correlations between structural and chemical states of cross-bridges in muscle. (1983) (0)
- Chemical Biology of Protein Lipidation: Semi-Synthesis and Structure Elucidation of Prenylated RabGTPases (2005) (0)
- Inhibition of ATPase with a disulfide analog of ATP (1973) (0)
- Inhibitors of HIV replication and methods for treating infections caused by one of the HIV (2001) (0)
- Human thymidylate kinase complexed with the bisubstrate inhibitor AZTP5A (2001) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 6) (2009) (0)
- Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp (2011) (0)
- 3D-STRUCTURE AND PROPERTIES OF WILDTYPE AND MUTANT H-RAS ENCODED P21 (1991) (0)
- Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 37) (2009) (0)
- Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase (2004) (0)
- Crystal structure of human Rab1b covalently bound to the GEF domain of DrrA/SidM from Legionella pneumophila in the presence of GDP (2017) (0)
- Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila (2010) (0)
- Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP (2011) (0)
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