Roger Schibli
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Computer Science
Roger Schibli's Degrees
- PhD Computer Science ETH Zurich
- Masters Computer Science University of Zurich
- Bachelors Computer Science University of Zurich
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(Suggest an Edit or Addition)Roger Schibli's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+ from [99mTcO4]- in Aqueous Solution and Its Reaction with a Bifunctional Ligand (1998) (559)
- Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [(99m)Tc(OH(2))3(CO)3]+. (2001) (346)
- Influence of the denticity of ligand systems on the in vitro and in vivo behavior of (99m)Tc(I)-tricarbonyl complexes: a hint for the future functionalization of biomolecules. (2000) (309)
- Metal chelating systems synthesized using the copper(I) catalyzed azide-alkyne cycloaddition. (2010) (309)
- Basic aqueous chemistry of [M(OH2)3(CO)3]+ (M=Re, Tc) directed towards radiopharmaceutical application (1999) (287)
- Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)–carbonyl complex (1999) (275)
- Current use and future potential of organometallic radiopharmaceuticals (2002) (269)
- Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase. (2010) (260)
- "Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step. (2006) (254)
- Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size. (2010) (221)
- Transglutaminase-based chemo-enzymatic conjugation approach yields homogeneous antibody-drug conjugates. (2014) (203)
- In vivo anti-tumor activity of the organometallic ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas (2014) (184)
- A Unique Matched Quadruplet of Terbium Radioisotopes for PET and SPECT and for α- and β−-Radionuclide Therapy: An In Vivo Proof-of-Concept Study with a New Receptor-Targeted Folate Derivative (2012) (167)
- In Vivo Imaging of Prostate Cancer Using [68Ga]-Labeled Bombesin Analog BAY86-7548 (2013) (165)
- Transplantation and Tracking of Human-Induced Pluripotent Stem Cells in a Pig Model of Myocardial Infarction: Assessment of Cell Survival, Engraftment, and Distribution by Hybrid Single Photon Emission Computed Tomography/Computed Tomography of Sodium Iodide Symporter Transgene Expression (2012) (164)
- Steps toward high specific activity labeling of biomolecules for therapeutic application: preparation of precursor [(188)Re(H(2)O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems. (2002) (154)
- "Click-to-chelate": design and incorporation of triazole-containing metal-chelating systems into biomolecules of diagnostic and therapeutic interest. (2008) (149)
- Promising Prospects for 44Sc-/47Sc-Based Theragnostics: Application of 47Sc for Radionuclide Tumor Therapy in Mice (2014) (147)
- Organometallic 99mTc-aquaion labels peptide to an unprecedented high specific activity. (1999) (138)
- DOTA Conjugate with an Albumin-Binding Entity Enables the First Folic Acid–Targeted 177Lu-Radionuclide Tumor Therapy in Mice (2013) (133)
- Folic Acid Conjugates for Nuclear Imaging of Folate Receptor–Positive Cancer (2011) (126)
- 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617—preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617 (2017) (124)
- New derivatives of vitamin B12 show preferential targeting of tumors. (2008) (111)
- ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo (2016) (109)
- The low-energy β(-) and electron emitter (161)Tb as an alternative to (177)Lu for targeted radionuclide therapy. (2010) (108)
- Reactions with the technetium and rhenium carbonyl complexes (NEt4)2[MX3(CO)3]. Synthesis and structure of [Tc(CN-But)3(CO)3](NO3) and (NEt4)[Tc2(μ-SCH2CH2OH)3(CO)6] (1996) (106)
- "Click-to-chelate": in vitro and in vivo comparison of a 99mTc(CO)3-labeled N(tau)-histidine folate derivative with its isostructural, clicked 1,2,3-triazole analogue. (2008) (99)
- Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. (2018) (95)
- Promises of Cyclotron-Produced 44Sc as a Diagnostic Match for Trivalent β−-Emitters: In Vitro and In Vivo Study of a 44Sc-DOTA-Folate Conjugate (2013) (90)
- Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors. (2006) (89)
- Metal carbonyl syntheses XXII. Low pressure carbonylation of [MOCl4]− and [MO4]−: the technetium(I) and rhenium(I) complexes [NEt4]2[MCl3(CO)3]☆ (1995) (89)
- 99mTc-labeling and in vivo studies of a bombesin analogue with a novel water-soluble dithiadiphosphine-based bifunctional chelating agent. (1999) (87)
- Influence of the molecular charge on the biodistribution of bombesin analogues labeled with the [99mTc(CO)3]-core. (2008) (87)
- Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy. (2018) (82)
- Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer (2019) (82)
- Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models. (2015) (81)
- A 99mTc(I)-postlabeled high affinity bombesin analogue as a potential tumor imaging agent. (2002) (80)
- Synthesis and in vitro characterization of organometallic rhenium and technetium glucose complexes against Glut 1 and hexokinase. (2005) (80)
- In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. (2010) (78)
- A "click chemistry" approach to the efficient synthesis of multiple imaging probes derived from a single precursor. (2009) (78)
- Derivatization of glucose and 2-deoxyglucose for transition metal complexation: substitution reactions with organometallic 99mTc and Re precursors and fundamental NMR investigations. (2001) (78)
- Can animal data predict human outcome? Problems and pitfalls of translational animal research (2012) (78)
- Antibody Conjugates: From Heterogeneous Populations to Defined Reagents (2015) (77)
- Direct in vitro and in vivo comparison of 161Tb and 177Lu using a tumour-targeting folate conjugate (2014) (77)
- Cyclotron production of (44)Sc: From bench to bedside. (2015) (77)
- 18F‐Radiolabeling of Aromatic Compounds Using Triarylsulfonium Salts (2012) (74)
- Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative. (2008) (73)
- SPECT Study of Folate Receptor-Positive Malignant and Normal Tissues in Mice Using a Novel 99mTc-Radiofolate (2008) (71)
- Novel glycated [99mTc(CO)3]-labeled bombesin analogues for improved targeting of gastrin-releasing peptide receptor-positive tumors. (2008) (70)
- Prospects in Folate Receptor-Targeted Radionuclide Therapy (2013) (69)
- Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies (2012) (69)
- [18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting. (2012) (67)
- Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics (2016) (65)
- Preclinical evaluation of novel organometallic 99mTc-folate and 99mTc-pteroate radiotracers for folate receptor-positive tumour targeting (2006) (64)
- Dosimetry and First Clinical Evaluation of the New 18F-Radiolabeled Bombesin Analogue BAY 864367 in Patients with Prostate Cancer (2015) (64)
- Folate Receptor Targeted Alpha-Therapy Using Terbium-149 (2014) (61)
- Cu(I)-catalyzed intramolecular cyclization of alkynoic acids in aqueous media: a "click side reaction". (2007) (60)
- Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography/computed tomography. (2011) (60)
- First Clinicopathologic Evidence of a Non–PSMA-Related Uptake Mechanism for 68Ga-PSMA-11 in Salivary Glands (2019) (56)
- Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization (2017) (55)
- Modification of different IgG1 antibodies via glutamine and lysine using bacterial and human tissue transglutaminase. (2008) (55)
- Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition (2016) (54)
- Future prospects for SPECT imaging using the radiolanthanide terbium-155 - production and preclinical evaluation in tumor-bearing mice. (2014) (54)
- Pemetrexed Improves Tumor Selectivity of 111In-DTPA-Folate in Mice with Folate Receptor–Positive Ovarian Cancer (2008) (54)
- Structural and (99)Tc NMR Investigations of Complexes with fac-[Tc(CO)(3)](+) Moieties and Macrocyclic Thioethers of Various Ring Sizes: Synthesis and X-ray Structure of the Complexes fac-[Tc(9-ane-S(3))(CO)(3)]Br, fac-[Tc(2)(tosylate)(2)(18-ane-S(6))(CO)(6)], and fac-[Tc(2)(20-ane-S(6)-OH)(CO)(6)][ (1998) (54)
- Management of chronic obstructive pulmonary disease: the Swiss guidelines. Official Guidelines of the Swiss Respiratory Society. (2002) (54)
- HYDROLYSIS OF THE ORGANOMETALLIC AQUA ION FAC-TRIAQUATRICARBONYLRHENIUM(I). MECHANISM, PKA, AND FORMATION CONSTANTS OF THE POLYNUCLEAR HYDROLYSIS PROD UCTS (1997) (53)
- A Click Approach to Structurally Diverse Conjugates Containing a Central Di‐1,2,3‐triazole Metal Chelate (2009) (53)
- 44Sc for labeling of DOTA- and NODAGA-functionalized peptides: preclinical in vitro and in vivo investigations (2016) (53)
- Potential of the "[M(CO)3]+" (M = Re, Tc) Moiety for the Labeling of Biomolecules (1997) (53)
- Quantification of Brain Glucose Metabolism by 18F-FDG PET with Real-Time Arterial and Image-Derived Input Function in Mice (2013) (53)
- Organometallic 99mTc-technetium(I)- and Re-rhenium(I)-folate derivatives for potential use in nuclear medicine (2004) (51)
- Anti-L1CAM radioimmunotherapy is more effective with the radiolanthanide terbium-161 compared to lutetium-177 in an ovarian cancer model (2014) (51)
- Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting. (2013) (50)
- The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor. (2009) (50)
- Evaluation of a novel radiofolate in tumour-bearing mice: promising prospects for folate-based radionuclide therapy (2009) (50)
- 47Sc as useful β–-emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes (2017) (49)
- Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β−-Particle, and Auger Electron Emitters (2017) (49)
- Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor. (2015) (48)
- First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study. (2017) (47)
- Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor. (2015) (46)
- Bis(thiosemicarbazones) as bifunctional chelators for the room temperature 64-copper labeling of peptides. (2010) (46)
- Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo (2017) (46)
- Gene expression levels of matrix metalloproteinases in human atherosclerotic plaques and evaluation of radiolabeled inhibitors as imaging agents for plaque vulnerability. (2014) (45)
- Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC. (2017) (45)
- Isostructural folate conjugates radiolabeled with the matched pair 99mTc/188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors. (2007) (45)
- Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy. (2016) (45)
- Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of 161Tb-folate and 177Lu-folate (2016) (44)
- 5-(2-18F-Fluoroethoxy)-l-Tryptophan as a Substrate of System L Transport for Tumor Imaging by PET (2012) (44)
- Synthesis, in vitro, and in silico evaluation of organometallic technetium and rhenium thymidine complexes with retained substrate activity toward human thymidine kinase type 1. (2008) (44)
- Dual, Site‐Specific Modification of Antibodies by Using Solid‐Phase Immobilized Microbial Transglutaminase (2017) (43)
- Synthesis and in vitro/in vivo evaluation of novel 99mTc(CO)3-folates. (2006) (43)
- Tumor targeting using 67Ga-DOTA-Bz-folate--investigations of methods to improve the tissue distribution of radiofolates. (2011) (43)
- In vitro and in vivo evaluation of bidentate, water-soluble phosphine ligands as anchor groups for the organometallic fac-[99mTc(CO)3]+-core. (1999) (42)
- Versatile synthetic approach to new bifunctional chelating agents tailor made for labeling with the fac-[M(CO)(3)](+) core (M = Tc, (99m)Tc, Re): synthesis, in vitro, and in vivo behavior of the model complex [M(APPA)(CO)(3)] (APPA = [(5-amino-pentyl)-pyridin-2-yl-methyl-amino]-acetic acid). (2003) (41)
- Ligand exchange reactions starting from [Re(CO)3Br3]2−. Synthesis, characterization and structures of rhenium(I) tricarbonyl complexes with thiourea and thiourea derivatives (1996) (41)
- Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties. (2017) (40)
- Evaluation of 11C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk (2017) (40)
- First organometallic inhibitors for human thymidine kinase: synthesis and in vitro evaluation of rhenium(I)- and technetium(I)-tricarbonyl complexes of thymidine (2003) (40)
- Imaging Atherosclerotic Plaque Inflammation via Folate Receptor Targeting Using a Novel 18F-Folate Radiotracer (2014) (40)
- PEGylation of (99m)Tc-labeled bombesin analogues improves their pharmacokinetic properties. (2011) (39)
- Radiolabeling and in vitro /in vivo evaluation of N‐(1‐adamantyl)‐8‐methoxy‐4‐oxo‐1‐phenyl‐1,4‐dihydroquinoline‐3‐carboxamide as a PET probe for imaging cannabinoid type 2 receptor (2013) (38)
- Structural Basis for Universal Corrinoid Recognition by the Cobalamin Transport Protein Haptocorrin* (2013) (38)
- Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET. (2016) (38)
- Targets and probes for non-invasive imaging of β-cells (2016) (37)
- Towards non-invasive imaging of vulnerable atherosclerotic plaques by targeting co-stimulatory molecules. (2014) (37)
- Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging of σ₂ receptors. (2013) (37)
- L1‐CAM‐targeted antibody therapy and 177Lu‐radioimmunotherapy of disseminated ovarian cancer (2012) (37)
- In vitro and in vivo targeting of different folate receptor-positive cancer cell lines with a novel 99mTc-radiofolate tracer (2006) (37)
- (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate. (2016) (37)
- Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis (2016) (37)
- Effects of antifolate drugs on the cellular uptake of radiofolates in vitro and in vivo. (2006) (35)
- Production and characterization of no-carrier-added 161Tb as an alternative to the clinically-applied 177Lu for radionuclide therapy (2019) (35)
- A New 18F-Labeled Folic Acid Derivative with Improved Properties for the PET Imaging of Folate Receptor–Positive Tumors (2010) (35)
- High-Resolution SPECT Imaging of Stimuli-Responsive Soft Microrobots. (2019) (35)
- Application of technetium and rhenium carbonyl chemistry to nuclear medicine. Preparation of [NEt4]2[TcCl3(CO)3] from [NBu4][TcO4] and structure of [NEt4][Tc2(μ-Cl)3(CO)6]; structures of the model complexes [NEt4][Re2(μ-OEt)2(μ-OAc)(CO)6] and [ReBr({-CH2S(CH2)2Cl}2)(CO)3] (1997) (34)
- Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer (2019) (34)
- Production and separation of 43Sc for radiopharmaceutical purposes (2017) (34)
- Alpha-PET for Prostate Cancer: Preclinical investigation using 149Tb-PSMA-617 (2019) (34)
- Single photon emission computed tomography tracer. (2013) (33)
- Complete Carbonylation of fac‐[Tc(H2O)3(CO)3]+ under CO Pressure in Aqueous Media: A Single Sample Story! (2000) (33)
- Design, synthesis, and initial evaluation of a high affinity positron emission tomography probe for imaging matrix metalloproteinases 2 and 9. (2013) (33)
- Cross sections of proton-induced reactions on 152Gd, 155Gd and 159Tb with emphasis on the production of selected Tb radionuclides (2014) (33)
- “2 + 1” Dithiocarbamate–isocyanide chelating systems for linking M(CO)3+ (M = 99mTc, Re) fragment to biomolecules (2004) (33)
- Molecular Assembly of Multifunctional 99mTc Radiopharmaceuticals Using “Clickable” Amino Acid Derivatives (2010) (33)
- Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity (2020) (33)
- Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy. (2015) (33)
- Cholecystokinin 2 Receptor Agonist 177Lu-PP-F11N for Radionuclide Therapy of Medullary Thyroid Carcinoma: Results of the Lumed Phase 0a Study (2019) (32)
- Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner (2015) (32)
- Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27) (2012) (31)
- Identification, characterization and suppression of side-products formed during the synthesis of high dose ⁶⁸Ga-DOTA-TATE. (2013) (30)
- A comparison of three 67/68Ga-labelled exendin-4 derivatives for β-cell imaging on the GLP-1 receptor: the influence of the conjugation site of NODAGA as chelator (2014) (30)
- Tumor Imaging in Patients with Advanced Tumors Using a New 99mTc-Radiolabeled Vitamin B12 Derivative (2014) (30)
- Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of (99m)Tc-EC20 in xenografted and syngeneic tumor-bearing mice. (2010) (30)
- Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering (2015) (30)
- Delivery of BMP-2 by two clinically available apatite materials: in vitro and in vivo comparison. (2015) (29)
- Strategies for the Development of Novel Tumor Targeting Technetium and Rhenium Radiopharmaceuticals (2007) (29)
- Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions. (2016) (29)
- Development of novel water-soluble, organometallic compounds for potential use in nuclear medicine: synthesis, characterization, and (1)H and (31)P NMR investigations of the complexes fac-[ReBr(CO)3L] (L=bis(bis(hydroxymethyl)phosphino)ethane, bis(bis(hydroxymethyl)phosphino)benzene). (2001) (29)
- DOTA-Functionalized Polylysine: A High Number of DOTA Chelates Positively Influences the Biodistribution of Enzymatic Conjugated Anti-Tumor Antibody chCE7agl (2013) (29)
- Preclinical evaluation and test–retest studies of [18F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5) (2014) (28)
- Tauvid™: The First FDA-Approved PET Tracer for Imaging Tau Pathology in Alzheimer’s Disease (2021) (28)
- Comparative studies of substitution reactions of rhenium(I) dicarbonyl-nitrosyl and tricarbonyl complexes in aqueous media. (2005) (28)
- Evaluation of the Radiolabeled Boronic Acid-Based FAP Inhibitor MIP-1232 for Atherosclerotic Plaque Imaging (2015) (28)
- Production and separation of ''non-standard'' PET nuclides at a large cyclotron facility: the experiences at the Paul Scherrer Institute in Switzerland. (2008) (28)
- Syntheses and characterization of dicarbonyl-nitrosyl complexes of technetium(I) and rhenium(I) in aqueous media: spectroscopic, structural, and DFT analyses. (2005) (28)
- Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors. (2017) (28)
- Radioiodinated folic acid conjugates: evaluation of a valuable concept to improve tumor-to-background contrast. (2012) (27)
- Synthesis and biological evaluation of ¹⁸F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imaging. (2013) (27)
- Radiolabeling of rituximab with (188)Re and (99m)Tc using the tricarbonyl technology. (2011) (27)
- Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals. (2017) (26)
- Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model (2014) (26)
- Charge dependent substrate activity of C3' and N3 functionalized, organometallic technetium and rhenium-labeled thymidine derivatives toward human thymidine kinase 1. (2010) (26)
- Functionalization of glucose at position C-3 for transition metal coordination: organo-rhenium complexes with carbohydrate skeletons. (2005) (26)
- Discovery of a fluorinated 4‐oxo‐quinoline derivative as a potential positron emission tomography radiotracer for imaging cannabinoid receptor type 2 (2016) (26)
- Improved PET Imaging of Tumors in Mice Using a Novel 18 F-Folate Conjugate with an Albumin-Binding Entity (2013) (26)
- Studies toward the development of new silicon-containing building blocks for the direct (18)F-labeling of peptides. (2013) (25)
- Versatile routes to C-2- and C-6-functionalized glucose derivatives of iminodiacetic acid. (2003) (25)
- Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18. (2016) (25)
- Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ1-Receptor–Targeted PET Imaging (2019) (24)
- Imaging Tumour ATB0,+ Transport Activity by PET with the Cationic Amino Acid O-2((2-[18F]fluoroethyl)methyl-amino)ethyltyrosine (2014) (24)
- The biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platforms (2013) (24)
- Steps towards [(C5Me5)TcO3]: Novel synthesis of [(C5Me5)Tc(CO)3] from [{Tc(μ3−OH)(CO)3}4] and oxidation of [(C5Me5)M(CO)3] (M = Tc, Re) with Br2 (1998) (24)
- Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor (2018) (24)
- A simple single-step synthesis of [99Tc3H3(CO)12] from [99TcO4]– and its X-ray crystal structure. Application to the production of no-carrier added [188Re3H3(CO)12] (1996) (24)
- HAX1 deficiency: Impact on lymphopoiesis and B‐cell development (2010) (24)
- Characterization of Different Osteosarcoma Phenotypes by PET Imaging in Preclinical Animal Models (2013) (24)
- Quantitative positron emission tomography of mGluR5 in rat brain with [18F]PSS232 at minimal invasiveness and reduced model complexity (2015) (24)
- First-in-Humans Application of 161Tb: A Feasibility Study Using 161Tb-DOTATOC (2021) (23)
- Microbial Transglutaminase and c‐myc‐Tag: A Strong Couple for the Functionalization of Antibody‐Like Protein Scaffolds from Discovery Platforms (2015) (22)
- Dose-dependent effects of (anti)folate preinjection on 99mTc-radiofolate uptake in tumors and kidneys. (2007) (22)
- 18F-AzaFol for Detection of Folate Receptor-β Positive Macrophages in Experimental Interstitial Lung Disease—A Proof-of-Concept Study (2019) (22)
- Synthesis and biological evaluation of (18)F-labeled Fluoroethoxy tryptophan analogues as potential PET tumor imaging agents. (2014) (22)
- Folate Receptor-Targeted Radionuclide Imaging Agents (2011) (21)
- Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue. (2018) (21)
- Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging. (2018) (21)
- Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals. (2015) (21)
- Synthesis, characterization and X-ray crystal structure of [Re(L4)(CO)3]Br·2CH3OH (L4 = N,N-bis[(2-diphenylphosphino)ethyl]-methoxyethylamine) : A model compound for novel cationic 99mTc(I)-tricarbonyl radiotracers useful for heart imaging (2006) (21)
- Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu]Lu-PSMA-ALB-56 in patients with mCRPC (2020) (21)
- On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion. (2020) (21)
- Novel peptide probes to assess the tensional state of fibronectin fibers in cancer (2017) (21)
- Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis. (2017) (21)
- Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2 (2018) (21)
- Novel Coordination Behavior of fac-[ReBr3(CO)3]2- with 1,3,5-Triaza-7-phosphaadamantane (PTA). Systematic Investigation on Stepwise Replacement of the Halides by PTA Ligand. Phase Transfer Studies and X-ray Crystal Structure of [NEt4][ReBr2((PTA)(CO)3], [ReBr(PTA)2(CO)3], and [Re(PTA)3(CO)3]PF6 (1998) (20)
- Targeted 64 Cu-labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging. (2019) (20)
- Structure-Affinity Relationships of 2,3,4,5-Tetrahydro-1H-3-benzazepine and 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-7-amine Analogues and the Discovery of a Radiofluorinated 2,3,4,5-Tetrahydro-1H-3-benzazepine Congener for Imaging GluN2B Subunit-Containing N-Methyl-d-aspartate Receptors. (2019) (19)
- Radiation dosimetry of 18F-AzaFol: A first in-human use of a folate receptor PET tracer (2020) (19)
- Comparison of Recombinant Human Haptocorrin Expressed in Human Embryonic Kidney Cells and Native Haptocorrin (2012) (19)
- Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging (2016) (19)
- Synthesis, in vitro and in silico assessment of organometallic Rhenium(I) and Technetium(I) thymidine complexes (2007) (19)
- L1 Cell Adhesion Molecule Confers Radioresistance to Ovarian Cancer and Defines a New Cancer Stem Cell Population (2020) (19)
- Synthesis and structures of technetium(I) and rhenium(I) tricarbonyl complexes with bis(diphenylthiophosphoryl)amide, |M(CO)3[(Ph2PS)2N](CH3CN)| (M = Tc, Re) (1998) (19)
- Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients (2018) (18)
- PEGylation, increasing specific activity and multiple dosing as strategies to improve the risk-benefit profile of targeted radionuclide therapy with 177Lu-DOTA-bombesin analogues (2012) (18)
- Glycation Methods for Bombesin Analogs Containing the (NαHis)Ac chelator for 99mTc(CO)3 Radiolabeling (2008) (18)
- CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers (2017) (18)
- Synthesis and Evaluation of Bombesin Analogues Conjugated to Two Different Triazolyl‐Derived Chelators for 99mTc Labeling (2010) (18)
- Peptides radiolabeled with Re-186/188 and Tc-99m as potential diagnostic and therapeutic agents (2007) (17)
- First Clinical Results of (d)-18F-Fluoromethyltyrosine (BAY 86-9596) PET/CT in Patients with Non–Small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma (2014) (17)
- Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis (2018) (17)
- Single-step radiofluorination of peptides using continuous flow microreactor. (2012) (17)
- Enzymatic antibody modification by bacterial transglutaminase. (2013) (17)
- Catabolism of neurotensins. Implications for the design of radiolabeling strategies of peptides. (1999) (17)
- Organometallic [Re(CO)3]+ and [Re(CO)2(NO)]2+ labeled substrates for human thymidine kinase 1. (2009) (17)
- Evaluation of ¹¹¹In-Labelled Exendin-4 Derivatives Containing Different Meprin β-Specific Cleavable Linkers (2015) (17)
- Synthesis of rhenium(I) and technetium(I) carbonyl/dithioether ligand complexes bearing 3,17β-estradiol (1997) (17)
- Therapeutic Potential of 47Sc in Comparison to 177Lu and 90Y: Preclinical Investigations (2019) (17)
- Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor (2014) (16)
- Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging. (2016) (15)
- Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging. (2016) (15)
- Scandium-44 DOTATOC PET/CT: First in-human molecular imaging of neuroendocrine tumors and possible perspectives for Theranostics (2015) (15)
- Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors. (2020) (14)
- Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model (2015) (14)
- Synthesis of tricarbonyl rhenium and technetium complexes of a 5′-carboxamide 5-ethyl-2′-deoxyuridine for selective inhibition of herpes simplex virus thymidine kinase 1 (2007) (14)
- Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting. (2019) (14)
- Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions. (2020) (14)
- Imaging atherosclerotic plaque inflammation via folate receptor targeting using a novel 18F-folate radiotracer. (2014) (14)
- MRS glucose mapping and PET joining forces: re‐evaluation of the lumped constant in the rat brain under isoflurane anaesthesia (2014) (13)
- Paclitaxel improved anti-L1CAM lutetium-177 radioimmunotherapy in an ovarian cancer xenograft model (2014) (13)
- Synthesis, radiolabelling and in vitro and in vivo evaluation of a novel fluorinated ABP688 derivative for the PET imaging of metabotropic glutamate receptor subtype 5. (2012) (13)
- Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting. (2020) (13)
- The A/T/N model applied through imaging biomarkers in a memory clinic (2019) (13)
- A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5 (2018) (13)
- GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET (2017) (13)
- Metal Chelating Systems Synthesized Using the Copper(I)‐Catalyzed Azide—Alkyne Cycloaddition (2010) (12)
- Methoxinine – an alternative stable amino acid substitute for oxidation‐sensitive methionine in radiolabelled peptide conjugates (2017) (12)
- Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging (2021) (12)
- FDG kinetic modeling in small rodent brain PET: optimization of data acquisition and analysis (2013) (12)
- Preclinical Development of 18F-OF-NB1 for Imaging GluN2B-Containing N-Methyl-d-Aspartate Receptors and Its Utility as a Biomarker for Amyotrophic Lateral Sclerosis (2020) (11)
- Elucidating the Structure-Activity Relationship of the Pentaglutamic Acid Sequence of Minigastrin with Cholecystokinin Receptor Subtype 2. (2019) (11)
- Synthesis and preliminary biological evaluation of O-2((2-[18F]fluoroethyl)methylamino)ethyltyrosine ([18F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging (2014) (11)
- Development and evaluation of novel PET tracers for imaging cannabinoid receptor type 2 in brain. (2014) (11)
- [(3)H]metyrapol and 4-[(131)i]iodometomidate label overlapping, but not identical, binding sites on rat adrenal membranes. (2013) (11)
- Evaluation of anti-VEGFR-3 specific scFv antibodies as potential therapeutic and diagnostic tools for tumor lymph-angiogenesis. (2007) (11)
- Brain Glucose Transport and Phosphorylation Under Acute Insulin-Induced Hypoglycemia in Mice: An 18F-FDG PET Study (2013) (11)
- Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors. (2019) (11)
- Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N (2020) (10)
- Fluorinated quinazolinones as potential radiotracers for imaging kinesin spindle protein expression. (2013) (10)
- Expression of functional folate receptors by human parathyroid cells. (2013) (10)
- Diving at diminished atmospheric pressure: air decompression tables for different altitudes. (1976) (10)
- Implementation of a new separation method to produce qualitatively improved 64 Cu. (2019) (10)
- Combination of terbium-161 with somatostatin receptor antagonists—a potential paradigm shift for the treatment of neuroendocrine neoplasms (2021) (10)
- Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering (2016) (10)
- A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice (2017) (10)
- In vivo Imaging of Cannabinoid Type 2 Receptors: Functional and Structural Alterations in Mouse Model of Cerebral Ischemia by PET and MRI (2021) (10)
- Albumin-Binding PSMA Radioligands: Impact of Minimal Structural Changes on the Tissue Distribution Profile (2020) (9)
- Simultaneous Visualization of 161Tb- and 177Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging (2021) (9)
- 165Er: A new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets. (2020) (9)
- Can Nuclear Imaging of Activated Macrophages with Folic Acid-Based Radiotracers Serve as a Prognostic Means to Identify COVID-19 Patients at Risk? (2020) (9)
- In Vivo Imaging of Local Inflammation: Monitoring LPS-Induced CD80/CD86 Upregulation by PET (2020) (9)
- First-in-Humans Brain PET Imaging of the GluN2B-Containing N-methyl-d-aspartate Receptor with (R)-11C-Me-NB1 (2021) (9)
- Radiosynthesis and evaluation of an 18F–labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma (2018) (8)
- Reduced 18F-Folate Conjugates as a New Class of PET Tracers for Folate Receptor Imaging. (2018) (8)
- In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs. (2018) (8)
- Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma (2018) (8)
- Evaluation of Actinium-225 Labeled Minigastrin Analogue [225Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy (2020) (8)
- Development of [(18)F]-PSS223 as a PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGluR5). (2012) (8)
- Combined Application of Albumin-Binding [177Lu]Lu-PSMA-ALB-56 and Fast-Cleared PSMA Inhibitors: Optimization of the Pharmacokinetics. (2020) (8)
- Recording Intracellular Molecular Events from the Outside: Glycosylphosphatidylinositol-Anchored Avidin as a Reporter Protein for In Vivo Imaging (2011) (8)
- In Vitro and In Vivo Characterization of a Novel Bifunctionalized Water-Soluble Dithia-Bisphosphine 99mTc Complex (1998) (8)
- Synthesis and In Vitro Evaluation of E- and Z-Geometrical Isomers of PSS232 as Potential Metabotropic Glutamate Receptors Subtype 5 (mGlu5) Binders (2013) (8)
- Synthesis and evaluation of novel α-fluorinated (E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyl oxime (ABP688) derivatives as metabotropic glutamate receptor subtype 5 PET radiotracers. (2012) (8)
- In vitro and in vivo evaluation of an innocuous drug cocktail to improve the quality of folic acid targeted nuclear imaging in preclinical research. (2013) (7)
- Recent progress in allosteric modulators for GluN2A subunit and development of GluN2A-selective nuclear imaging probes. (2019) (7)
- The influence of physical work upon decompression time after simulated oxy-helium dives. (1972) (7)
- Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice (2018) (7)
- [Measurement of nasal airway resistance: methods and normal values]. (1973) (7)
- Radiopharmaceuticals: From molecular imaging to targeted radionuclide therapy (2004) (7)
- GABA A receptor subtypes in the mouse brain : Regional mapping and diazepam receptor occupancy by in vivo [ 18 F ] flumazenil PET (2017) (7)
- Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4 (2019) (7)
- Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaques (2015) (7)
- Synthesis of a Novel γ-FolicAcid-Nτ-HistidineConjugate Suitable for Labeling with 99mTcand 188Re (2009) (6)
- Technetium in Medicine (2007) (6)
- Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging. (2015) (6)
- Functionalization of glucose for the labeling with 99mTc‐tricarbonyl (2001) (6)
- Production of Mass-Separated Erbium-169 Towards the First Preclinical in vitro Investigations (2021) (6)
- Diastereomerically Pure 6R- and 6S-3′-Aza-2′-18F-Fluoro-5-Methyltetrahydrofolates Show Unprecedentedly High Uptake in Folate Receptor–Positive KB Tumors (2018) (6)
- Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates (2018) (6)
- Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma (2018) (5)
- Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy (2020) (5)
- Synthesis and Evaluation of Biphenyl Compounds as Kinesin Spindle Protein Inhibitors (2013) (5)
- [18F]Flurpiridaz: Facile and Improved Precursor Synthesis for this Next‐Generation Cardiac Positron Emission Tomography Imaging Agent (2020) (5)
- Chemoselective 18F-incorporation into pyridyl acyltrifluoroborates for rapid radiolabelling of peptides and proteins at room temperature. (2019) (5)
- Radiometal labeling of antibodies and antibody fragments for imaging and therapy. (2004) (5)
- Making the step from diagnosis to therapy: Improved 99mTc/188Re‐tricarbonyl preparation for high specific activity labeling of biomolecules (2001) (5)
- Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model (2020) (5)
- 1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs. (2021) (5)
- [11C]mHED PET follows a two-tissue compartment model in mouse myocardium with norepinephrine transporter (NET)-dependent uptake, while [18F]LMI1195 uptake is NET-independent (2020) (5)
- SYNTHESIS AND STRUCTURE AFFINITY RELATIONSHIP OF SMALL MOLECULES FOR IMAGING HUMAN CD80 BY POSITRON EMISSION TOMOGRAPHY. (2019) (5)
- Water-exchange study revealed unexpected substitution behavior of [(CO)2(NO)Re(H2O)3]2+ in aqueous media. (2006) (5)
- Impact of the mouse model and molar amount of injected ligand on the tissue distribution profile of PSMA radioligands (2021) (5)
- 1 In Vivo Imaging of Prostate Cancer Using [ 68 Ga ]-Labeled Bombesin Analog BAY 86-7548 (2013) (5)
- Targeted Radiotherapeutics from 'Bench-to-Bedside'. (2020) (4)
- Synthesis of Precursors for (18)F-Labeling of Folic Acid for PET Application (2011) (4)
- Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [18F]PSS232 in the Rat Brain (2018) (4)
- An Overview of Targeted Radiotherapy (2019) (4)
- Combination of Proton Therapy and Radionuclide Therapy in Mice: Preclinical Pilot Study at the Paul Scherrer Institute (2019) (4)
- Rest/stress myocardial perfusion imaging by positron emission tomography with 18F-Flurpiridaz: A feasibility study in mice (2021) (4)
- Therapeutic Potential of 47 Sc in Comparison to 177 Lu and 90 Y : Preclinical Investigations (2019) (4)
- The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute. (2020) (3)
- Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14–16, 2018; Vienna, Austria (2019) (3)
- Role of sex hormones in modulating myocardial perfusion and coronary flow reserve (2022) (3)
- Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging. (2017) (3)
- Transplantation and Tracking of Human Induced Pluripotent Stem Cells in a Pig Model of Myocardial Infarction: Assessment of Cell Survival, Engraftment and Distribution by Hybrid SPECT-CT Imaging of Sodium Iodide Symporter Trangene Expression (2012) (3)
- Evaluation of the CCK-2 receptor agonist 177Lu-PP-F11N for radionuclide therapy of medullary thyroid carcinoma - final Results of the phase 0 'Lumed' Study (2019) (3)
- Therapeutic Response of CCKBR-Positive Tumors to Combinatory Treatment with Everolimus and the Radiolabeled Minigastrin Analogue [177Lu]Lu-PP-F11N (2021) (3)
- Synthesis and Biological Evaluation of Quinoxaline Derivatives for PET Imaging of the NMDA Receptor (2017) (3)
- Assessment of an elastin binding molecule for PET imaging of atherosclerotic plaques. (2013) (3)
- Unexpected reactivity of cyclic perfluorinated iodanes with electrophiles. (2018) (3)
- Chapter 3 In vivo anti-tumor activity of the organometallic ruthenium ( II )-arene complex [ Ru ( ɳ 6p-cymene ) Cl 2 ( pta ) ] ( RAPTA-C ) in human ovarian and colorectal carcinomas (2015) (3)
- Design and Evaluation of Novel Albumin-Binding Folate Radioconjugates: Systematic Approach of Varying the Linker Entities. (2022) (3)
- Structural investigations of re‐tricarbonyl labeled neurotensin analogues using 1D and 2D “magic angle spinning” NMR techniques (2001) (3)
- Synthesis and Biological Evaluation of Quinoxaline Derivatives for PET Imaging of the NMDA Receptor (2017) (3)
- Distance-Dependent Cellular Uptake of Oligoproline-Based Homobivalent Ligands Targeting GPCRs-An Experimental and Computational Analysis. (2020) (3)
- The production of 161Tb and its introduction to the clinic through the Good Manufacturing Practice-compliant radiolabeling of [161Tb]Tb-DOTATOC (2021) (3)
- A33 FOLATE MEDIATED IMAGING OF ACTIVATED MACROPHAGES IN EXPERIMENTAL OSTEOARTHRITIS USING SPECT/CT (2008) (3)
- Synthesis and in vitro/in vivo pharmacological evaluation of [11C]-ThioABP, a novel radiotracer for imaging mGluR5 with PET (2013) (3)
- Identification of a PET Radiotracer for Imaging of the Folate Receptor-α: A Potential Tool to Select Patients for Targeted Tumor Therapy (2021) (3)
- Development and evaluation of (44)Ti production on high energy protons (2011) (3)
- 268 DEVELOPMENT OF 44SC PRODUCTION FOR RADIOPHARMACEUTICAL APPLICATIONS (2012) (3)
- Neuroimaging with Radiopharmaceuticals Targeting the Glutamatergic System. (2020) (2)
- Abstract P4-21-18: Pre-clinical antitumor activity, tumor localization, and pharmacokinetics of MP0274, an apoptosis inducing, biparatopic HER2-targeting DARPin® (2017) (2)
- Preclinical Investigations to Explore the Difference between the Diastereomers [177Lu]Lu-SibuDAB and [177Lu]Lu-RibuDAB toward Prostate Cancer Therapy. (2022) (2)
- Improved Tumor-Targeting with Peptidomimetic Analogs of Minigastrin 177Lu-PP-F11N (2021) (2)
- 1 Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography (2016) (2)
- Cyclotrons Operated for Nuclear Medicine and Radiopharmacy in the German Speaking D-A-CH Countries: An Update on Current Status and Trends (2022) (2)
- of the organometallic ruthenium ( II )-arene complex [ Ru ( h 6p-cymene )-Cl 2 ( pta ) ] ( RAPTA-C ) in human ovarian and colorectal carcinomas † (2014) (2)
- Blood coagulation during critical decompression following diving experiments with oxygen-helium. (1973) (2)
- Evaluation of 5H‐Thiazolo[3,2‐α]pyrimidin‐5‐ones as Potential GluN2A PET Tracers (2020) (2)
- Additional file 1: of Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis (2016) (2)
- Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone (2021) (2)
- [Experimental studies on decompression following diving in mountain lakes at reduced air pressure]. (1973) (2)
- [225Ac]Ac-SibuDAB for Targeted Alpha Therapy of Prostate Cancer: Preclinical Evaluation and Comparison with [225Ac]Ac-PSMA-617 (2022) (2)
- Application of click chemistry to the design of ligand systems and functionalization of biomolecules suitable for radiolabelling with the technetium and rhenium tricarbonyl core; ; IAEA radioisotopes and radiopharmaceuticals series; Technetium-99m radiopharmaceuticals : status and trends (2009) (2)
- Synthetic and structural considerations of organometallic compounds of the elements technetium and rhenium for use in radiopharmacy (2003) (2)
- Abstract 3029: FAP-mediated tumor accumulation of a T-cell agonistic FAP/4-1BB DARPin drug candidate analyzed by SPECT/CT and quantitative biodistribution (2018) (2)
- Radiosynthesis and pre-clinical evaluation of Al18F labeled bombesin antagonist: Promising tracer for prostate cancer imaging (2012) (1)
- The CCK-2 receptor agonist Lu-177-PP-F11N for PRRT of medullary thyroid cancer – Recent results of the phase 1 “LUMED” Study (2021) (1)
- Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging. (2022) (1)
- Evaluation of 99 mTc-rhAnnexin V-128 SPECT / CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis (2018) (1)
- In Vivo Imaging of Prostate Cancer Using ( 68 Ga)-Labeled (2013) (1)
- Production of four terbium-radioisotopes for radiopharmaceutical applications (2012) (1)
- Bifunctional Chelation Systems Based on Hydroxymethyl Phosphine-Based Donor Groups (1999) (1)
- Erratum: Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering (2015) (1)
- Dual MVK cleavable linkers effectively reduce renal retention of 111In-fibronectin-binding peptides. (2022) (1)
- Abstract LB-106: Overcoming limitations of current Antibody-Drug Conjugates (ADCs) by a novel linker technology (2019) (1)
- Novel Synthetic Strategies Enable the Efficient Development of Folate Conjugates for Cancer Radiotheranostics. (2021) (1)
- [Lung biopsy in interstitial pulmonary processes]. (1976) (1)
- Cancer esearch or and Stem Cell Biology ivo Imaging of Inflammation-and Tumor-Induced Lymph e Lymphangiogenesis by Immuno – Positron R ission Tomography (2010) (1)
- A preliminary comparison of methods for production of 188Re‐C595 antibody for radioimmunotherapy of bladder cancer (2001) (1)
- Preclinical application of 47Sc-folate – A pilot study in tumor-bearing mice (2014) (1)
- Synthesis and characterization of [99mTc]metomidate as the tricarbonyl-conjugate (2001) (1)
- The use of 149Tb and 152Tb in preclinical investigations: an update on its mass separation and subsequent application for imaging and therapy (2016) (1)
- Preclinical investigations using [177Lu]Lu-Ibu-DAB-PSMA toward its clinical translation for radioligand therapy of prostate cancer (2022) (1)
- Design and Development of New Hydroxy Methyl Phosphine Based Bifunctional Chelating Agents (BFCAs) for Use in Radiopharmaceutical Applications (1999) (1)
- Synthesis of a Novel g-Folic Acid – N t-Histidine Conjugate Suitable for Labeling with 99 mTc and 188 Re (2009) (1)
- Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold. (2022) (1)
- Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans (2019) (1)
- Studies toward terminal (fluoroalkyl)silanes. Investigation of diethylaminosulfur trifluoride (DAST) in exchange reactions with some terminal (hydroxyalkyl)silanes (2014) (1)
- 18th European Symposium on Radiopharmacy and Radiopharmaceuticals (2016) (1)
- Single Photon Emission Computed Tomography Tracer. (2020) (1)
- 177Lu-labelled peptidomimetics: novel minigastrin analogues for improved tumour targeting (2019) (1)
- Corrigendum concerning “Methoxinine—An alternative stable amino acid substitute for oxidation‐sensitive methionine in radiolabelled peptide conjugates” (2020) (0)
- Triazole Based Chelating Systems for the Tc/Re-Tricarbonyl Core (2007) (0)
- Cell membrane localization of terbium-161 using peptide receptor antagonists: can we profit from Auger electron emission with non-internalizing targeting agents? (2022) (0)
- Personalized Health 2020 29 and 30 June 2020 Virtual Only Personalized (2020) (0)
- Development and application of first Sc-44-labeled Affibody molecule (2016) (0)
- PNS as tridentate ligand system for the synthesis of Tc(I) and Re(I) tricarbonyl complexes (2001) (0)
- Terbium radionuclides for theranostics (2021) (0)
- Should new Nuclear Reactors be considered as an option to solve Technetium shortage problem (2012) (0)
- Abstract 2514: Towards homogenous adcs: A new site-specific antibody conjugation using bacterial transglutaminase (btg-adc) (2014) (0)
- Development of novel cannabinoid type 2 receptor tracers for PET imaging (2013) (0)
- 64Cu-Labeled Folate Radioconjugate for PET Imaging of Folate Receptor-Positive Tumors (2016) (0)
- 37: 152/161Tb-DOTA-RM6 biodistribution studies in prostate cancer bearing SCID mice and 149Tb sources from CERN-MEDICIS (2014) (0)
- Novel peptide probes to assess the tensional state of fibronectin fibers in cancer (2017) (0)
- Novel folic acid radioconjugate with an albumin binding entity : Improved anti-tumor efficacy and reduced side effects (2018) (0)
- Reducing the renal retention of 111In-labelled fibronectin-binding peptides through brush border-enzyme sensitive cleavable linkers (2022) (0)
- Radiopharmaceuticals for Targeted Tumor Diagnosis and Therapy (2000) (0)
- Targeting the immune co-stimulatory molecule CD80 for the imaging of vulnerable atherosclerotic plaques by PET (2014) (0)
- Novel approaches in the radiopharmacy of 99Tcm and 186/188Re (1997) (0)
- Pilot study of a new Tc-99m labeled vitamin B12 derivative for detection of cancer (2010) (0)
- Novel folate radioconjugates: optimization of functional units to improve the tissue distribution profile (2022) (0)
- Radiosynthesis and evaluation of 18F-2'-fluoro-3'-aza folic acid as a potential PET ligand for imaging folate receptor-positive tumors (2012) (0)
- Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT) (2022) (0)
- Investigations of terbium-161 towards prostate cancer therapy using albumin-binding and standard PSMA ligands (2022) (0)
- Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma (2018) (0)
- High-sensitivity ICP-MS – an alternative for in vitro and in vivo characterization of future radiometal-based theranostic candidates (2022) (0)
- Systematic Coordination of Water-Soluble Monoand Bidentate Phosphine Ligands to the Organometallic Precursor fac-[Rebr3(Co)3]2- (1999) (0)
- Imaging , Diagnosis , Prognosis In Vivo Imaging of Prostate Cancer Using [ 68 Ga ]-Labeled Bombesin Analog BAY 86-7548 (2013) (0)
- Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain. (2022) (0)
- Targeting mTORC1 Activity to Improve Efficacy of Radioligand Therapy in Cancer (2022) (0)
- 1 2 Animal SPECT imaging with multi-pinhole apertures and fusion with MRI (0)
- Microbial Transglutaminase as a Versatile Tool for Site-Specific Protein Modification (2015) (0)
- Production of high-specific-activity erbium-169, ytterbium-175 and thulium-167 (2022) (0)
- Kidney protection after a high dose of 177Lu-DOTA-Bz-folate (2012) (0)
- Age-dependent cardiac remodelling – role of sex hormones (2020) (0)
- OP0083 Molecular targeted imaging biomarkers for personalized medicine strategies in systemic sclerosis-related interstitial lung disease (2017) (0)
- Promising potential of [Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model (2020) (0)
- Title page (2019) (0)
- Clinical SPECT radiopharmaceuticals (2016) (0)
- Click chemistry for PET and SPECT (2009) (0)
- Medically interesting radiolanthanide terbium-161: from production towards clinical application (2019) (0)
- Structure-activity relationship of pyrazol-4-yl-pyridine derivatives for imaging the muscarinic acetylcholine receptor M4 (2022) (0)
- Translational immunoPET/MR imaging of invasive pulmonary aspergillosis (2019) (0)
- Reactivity of the novel organometallic aqua-ion [(CO)2(NO)Re(H2O) 3]2+: Kinetics of H2O substitution and 17O exchange of CO ligands (2005) (0)
- FRI0358 99MTC-RHANNEXIN V-128 as a novel early diagnostic marker for interstitial lung disease associated with systemic sclerosis (2017) (0)
- Improved Syntheses of the mGlu5 Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling (2018) (0)
- A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides (2023) (0)
- [Effect of a new oral remedy for a cold (HSP 525 A) on flow resistance of the nose]. (1973) (0)
- Antibody targeting of epithelial carcinoma-associated fibroblast activation protein blocks cellular proliferation, migration, and invasion. (2010) (0)
- 270 177LU QUALITY ANALYSIS FOR AN EFFICIENT PREPARATION OF 177LU-LABELED COMPOUNDS (2012) (0)
- Improving the quality of Ga radionuclides to achieve high radiolabeling yields (2022) (0)
- 203: Moving forward in radionuclide development in Switzerland (2014) (0)
- Abstract 3386:In vivoimaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography (2010) (0)
- Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake (2021) (0)
- Cover Picture: Molecular Assembly of Multifunctional 99mTc Radiopharmaceuticals Using “Clickable” Amino Acid Derivatives (ChemMedChem 12/2010) (2010) (0)
- Targeted alpha tumour therapy and other oncological solutions (TATTOOS) as part of Paul Scherrer Institute’s IMPACT large facilities project (2022) (0)
- 44Sc production development from 44Ca for radiopharmaceutical application (2014) (0)
- Abstract 5037: DARPins as powerful targeting agents for radioligand therapeutics (2023) (0)
- New radiolabeled derivatives of vitamin B12 with abolished transcobalamin II binding reveal selective targeting of tumors (2007) (0)
- The development of terbium-155 and terbium-161 towards radiotheragnostic clinical applications (2022) (0)
- Yes we can! First report on folic acid targeted radionuclide tumor therapy (2012) (0)
- Development of a novel reversible monoacylglycerol lipase PET tracer bearing a morpholine-3-one scaffold (2022) (0)
- Effects of the antifolate pemetrexed on radiofolate uptake and distribution in FR-positive tumors and kidneys (2007) (0)
- In vitro and in vivo evaluation of a novel 67Ga-DOTA-folate in KB-tumor bearing mice (2010) (0)
- Pharmacokinetic of a new Tc-99m labeled vitamin B12 derivative with abolished binding to TC: A story of mice and man (2010) (0)
- Cu(I)-Catalyzed Intramolecular Cyclization of Alkynoic Acids in Aqueous Media: A “Click Side Reaction”. (2008) (0)
- Synthesis and biological evaluation of ((5-hydroxy(2-(3-[18F]fluoropropyl))tryptophan ([18F]5OH-2FPTRP) as a potential PET tumor imaging agent (2014) (0)
- Production and radiochemical separation of terbium-155 from enriched gadolinium target material and its preliminary application in SPECT imaging (2022) (0)
- Signaling Network Response to Alpha-Particle Targeted Therapy with Actinium-225 Labeled Minigastrin Analogue 225Ac-PP-F11N Reveals Radiosensitizing Potential of HDAC Inhibitors. (2023) (0)
- Targeting the GLP-1 receptor on pancreatic beta-cells: signaling and radiopharmaceutical applications (2019) (0)
- 99mTc(CO)3 radiolabeled Re(Arg11)CCMSH for melanoma SPECT imaging (2009) (0)
- Targeted Radionuclide Therapy with 161Tb: Investigation of Anti-Tumor Effects and Undesired Side Effects (2016) (0)
- Pathogen specific antibody-based molecular imaging of Invasive Aspergillosis with the newly developed PET tracer [64Cu]DOTA-JF5 and its humanized variant [64Cu]NODAGA-hJF5 (2015) (0)
- Preclinical study of a novel 99mTc-radiofolate with improved characteristics for folate receptor-positive tumor targeting (2007) (0)
- Addendum 3 to the ISOLDE and Neutron Time-of-Flight Committee IS 528 Novel diagnostic and therapeutic radionuclides for the development of innovative radiopharmaceuticals 11 January 2017 (2017) (0)
- [Coronary blood flow during exercise in coronary sclerosis, measured using the precordial xenon-clearance technic]. (1973) (0)
- First-in-man evaluation of [18F]-PSS232, a fluorinated PET tracer for mGluR5 (2015) (0)
- 177 THERANOSTICS OF FOLATE RECEPTOR POSITIVE CANCER USING TERBIUM-RADIOLABELED FOLATE CONJUGATES (2012) (0)
- Inductively Coupled Plasma Mass Spectrometry─A Valid Method for the Characterization of Metal Conjugates in View of the Development of Radiopharmaceuticals. (2023) (0)
- F-18 -PSS232-A novel PET radiotracer for imaging of metabotropic glutamate receptors subtype 5 (mGluR5) (2013) (0)
- Carbonmonoxidquelle for the production of transition metal carbonyl (2000) (0)
- Impact on management of Gallium-68 DOTATATE PET/CT in patients with neuroendocrine tumors (2012) (0)
- SUN-334 Evaluation of the CCK-2 Receptor Agonist 177Lu-PP-F11N for PRRT of Medullary Thyroid Carcinoma: Results of a Phase 0 "Lumed" Study (2019) (0)
- Aqueous Media: A Single Sample Story!** (2000) (0)
- FEMAET: a Cationic Amino Acid PET Probe Targeting the Concentrative Amino Acid Transporter ATB0,+ (2013) (0)
- Radiosynthesis, in vitro and in vivo characterization of O-(2- (18)F fluoroethyl)-5-hydroxy-L-tryptophan (2011) (0)
- Synthesis and preliminary biological evaluation of O-2((2-[18F]fluoroethyl)methylamino)ethyltyrosine ([18F]FEMAET) as a potential cationic amino acid PET tracer for tumor imaging (2014) (0)
- OP0045 Early Detection of Lung Involvement in Systemic Sclerosis Using Molecular Targeted Imaging (2016) (0)
- Front Cover: Evaluation of 5 H ‐Thiazolo[3,2‐α]pyrimidin‐5‐ones as Potential GluN2A PET Tracers (ChemMedChem 24/2020) (2020) (0)
- Crystal Structure of Haptocorrin in Complex with CNCbl (2013) (0)
- Title Evaluation of the CCK-2-receptor agonist 177Lu-PP-F11N for peptide receptor radionuclide therapy (PRRT) of medullary thyroid carcinoma - First results of a phase 0 'Lumed' Study (2018) (0)
- Radioligand development for imaging cannabinoid receptor subtype 2 with PET (2014) (0)
- Optimization and stability studies of thymidine analog complex with organometallic core (2006) (0)
- Implementing subtype‐specific pre‐clinical models of breast cancer to study pre‐treatment aspirin effects (2022) (0)
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What Schools Are Affiliated With Roger Schibli?
Roger Schibli is affiliated with the following schools: