Ron Laskey | Academic Influence

Ron Laskey's AcademicInfluence.com Rankings

Ron Laskey

Biology

#2398

World Rank

#3808

Historical Rank

Cell Biology

#111

World Rank

#116

Historical Rank

biology Degrees

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Biology

Why Is Ron Laskey Influential?

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According to Wikipedia, Ronald Alfred Laskey FLSW is a British cell biologist and cancer researcher. Career and research Laskey was the Charles Darwin Professor of Embryology at the University of Cambridge. In 1991, he co-founded the Wellcome Trust/Cancer Research Campaign Institute , along with five other senior scientists including Professor Sir John Gurdon. In 2001, he founded the Medical Research Council Cancer Cell Unit in 2001, and was Director of the Unit until 2010. Laskey is also a Fellow of Darwin College, Cambridge.

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Ron Laskey's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. (1974) (7428)
Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. (1975) (3941)
Nuclear targeting sequences--a consensus? (1991) (1874)
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence (1991) (1488)
Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized film (1977) (782)
Isolation of a protein that is essential for the first step of nuclear protein import (1994) (705)
Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA (1978) (696)
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs (1986) (589)
A role for the nuclear envelope in controlling DNA replication within the cell cycle (1988) (584)
Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores (1988) (529)
Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope (1995) (512)
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus (1982) (509)
Distinct functions for the two importin subunits in nuclear protein import (1995) (473)
Protein import into the cell nucleus. (1986) (463)
A 41 amino acid motif in importin‐alpha confers binding to importin‐beta and hence transit into the nucleus. (1996) (428)
S phase of the cell cycle. (1989) (364)
Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. (1999) (348)
Improved cervical smear assessment using antibodies against proteins that regulate DNA replication. (1998) (336)
Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System (1997) (324)
Distinct roles for cyclins E and A during DNA replication complex assembly and activation (2002) (311)
The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis. (1980) (307)
Regulated replication of DNA microinjected into eggs of Xenopus laevis (1980) (305)
Assembly of SV40 chromatin in a cell-free system from Xenopus eggs (1977) (298)
MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells (1995) (275)
Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin (1991) (272)
High sequence specificity of micrococcal nuclease. (1981) (269)
The developmental capacity of nuclei transplanted from keratinized skin cells of adult frogs. (1975) (265)
Genes in development (1977) (265)
Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids (1996) (259)
Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs (1988) (230)
Two complexes that contain histones are required for nucleosome assembly in vitro: Role of nucleoplasmin and N1 in Xenopus egg extracts (1987) (229)
The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin (1996) (219)
Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals. (1987) (218)
The Extracellular Matrix Protein TGFBI Induces Microtubule Stabilization and Sensitizes Ovarian Cancers to Paclitaxel (2007) (207)
Assembly of nucleosomes: the reaction involving X. laevis nucleoplasmin (1980) (202)
Importin Provides a Link between Nuclear Protein Import and U snRNA Export (1996) (193)
Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. (1989) (190)
Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism (2005) (181)
Control of DNA replication and its potential clinical exploitation (2005) (174)
Control of mammalian gene expression by selective mRNA export (2015) (173)
Regulation of eukaryotic DNA replication. (1994) (170)
A rotary pumping model for helicase function of MCM proteins at a distance from replication forks (2003) (161)
Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication. (1996) (159)
Minichromosome maintenance protein 2 is a strong independent prognostic marker in breast cancer. (2003) (156)
Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool (2002) (153)
Cdc6 protein causes premature entry into S phase in a mammalian cell‐free system (1998) (151)
An acidic protein which assembles nucleosomes in vitro is the most abundant protein in Xenopus oocyte nuclei. (1980) (146)
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. (2006) (138)
The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in Xenopus egg extract (1992) (133)
Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process. (2000) (129)
The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells. (2000) (128)
The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts (1995) (125)
Human Minichromosome Maintenance Proteins and Human Origin Recognition Complex 2 Protein on Chromatin* (1998) (121)
mRNA Export from Mammalian Cell Nuclei Is Dependent on GANP (2010) (120)
Selective DNA conservation and chromatin assembly after injection of SV40 DNA into Xenopus oocytes. (1978) (115)
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export (2012) (110)
Protein synthesis in oocytes of xenopus laevis is not regulated by the supply of messenger RNA (1977) (108)
Geminin predicts adverse clinical outcome in breast cancer by reflecting cell‐cycle progression (2004) (104)
Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine (1999) (103)
Genetic Content of Adult Somatic Cells tested by Nuclear Transplantation from Cultured Cells (1970) (97)
MCM Proteins Are Associated with RNA Polymerase II Holoenzyme (1999) (97)
Translational approaches to improving cervical screening (2003) (97)
Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle. (2000) (91)
A novel immunohistochemical method to estimate cell‐cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer (2003) (90)
Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor (1993) (88)
XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication. (1996) (86)
The transplantation of nuclei from single cultured cells into enucleate frogs' eggs. (1970) (85)
Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions (2003) (84)
MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3 (2001) (84)
The nuclear membrane determines the timing of DNA replication in Xenopus egg extracts (1991) (83)
Geminin Escapes Degradation in G1 of Mouse Pluripotent Cells and Mediates the Expression of Oct4, Sox2, and Nanog (2011) (82)
Hyperphosphorylation of Nucleoplasmin Facilitates Xenopus Sperm Decondensation at Fertilization (*) (1996) (82)
Regular ArticleNuclear chaperones (2000) (79)
Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects (2005) (79)
Viral Cyclin–Cyclin-Dependent Kinase 6 Complexes Initiate Nuclear DNA Replication (2001) (79)
A 41 amino acid motif in importin-a confers binding to importin-, and hence transit into the nucleus (76)
Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity. (2013) (75)
DNA replication occurs at discrete sites in pseudonuclei assembled from purified DNA in vitro (1991) (74)
Nuclear shuttling: The default pathway for nuclear proteins? (1993) (69)
Retinoic acid-induced glandular differentiation of the oesophagus (2006) (69)
Nuclear import: A tale of two sites (1998) (66)
Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis (2003) (66)
The role of nucleoplasmin in chromatin assembly and disassembly. (1993) (66)
Reprogramming of transplanted nuclei in amphibia. (1979) (63)
Loss of p21CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence (2009) (63)
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP (2014) (63)
Interpreting crosstalk between TNF-alpha and NGF: potential implications for disease. (2008) (60)
Nucleosome assembly (1980) (60)
A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia (2006) (58)
Nucleoplasmin: the archetypal molecular chaperone. (1990) (57)
[27] Assembly of nucleosomes and chromatin in Vitro (1989) (57)
Induction of polyoma DNA synthesis by injection into frog-egg cytoplasm. (1973) (53)
Early recurrence of benign meningioma correlates with expression of mini-chromosome maintenance-2 protein (2002) (53)
Chromatin assembly and transcription in eggs and oocytes of Xenopus laevis. (1978) (51)
Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia (2003) (47)
Replication origins in the eucaryotic chromosome (1981) (47)
MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India (2007) (45)
The MCM3 Acetylase MCM3AP Inhibits Initiation, but Not Elongation, of DNA Replication via Interaction with MCM3* (2002) (44)
Chromosome replication in early development of Xenopus laevis. (1985) (44)
Molecular and cellular characterization of CRP1, a Drosophila chromatin decondensation protein. (1997) (43)
DNA replication in cell-free extracts from Xenopus laevis. (1991) (43)
Interaction of Xenopus Cdc2·Cyclin A1 with the Origin Recognition Complex* (2000) (41)
Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis. (1972) (41)
Xenopus c-ski contains a novel coiled-coil protein domain, and is maternally expressed during development. (1993) (39)
Assembly of nucleosomes and chromatin in vitro. (1989) (38)
Tumor necrosis factor alpha regulates responses to nerve growth factor, promoting neural cell survival but suppressing differentiation of neuroblastoma cells. (2007) (36)
Replication proteins and human disease. (2014) (35)
Protein kinase inhibition in G2 causes mammalian Mcm proteins to reassociate with chromatin and restores ability to replicate. (1998) (34)
Assembly of the cell nucleus. (1990) (33)
Geminin bans replication licence (2001) (31)
The use of antibiotics in the preparation of amphibian cell cultures from highly contaminated material. (1970) (30)
Chromosome replication in cell-free systems from Xenopus eggs. (1987) (30)
Regulatory roles of the nuclear envelope. (1996) (29)
The Croonian Lecture 2001 Hunting the antisocial cancer cell: MCM proteins and their exploitation (2005) (29)
Improved Screening for Anal Neoplasia by Immunocytochemical Detection of Minichromosome Maintenance Proteins (2008) (27)
Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine (2012) (26)
Tumor promoter TPA increases initiation of replication on DNA injected into Xenopus eggs (1983) (26)
GANP enhances the efficiency of mRNA nuclear export in mammalian cells (2010) (25)
Detection of S-phase cells in tissue sections by in situ DNA replication (2000) (22)
Chromatin-bound Cdc 6 persists in S and G 2 phases in human cells , while soluble Cdc 6 is destroyed in a cyclin A-cdk 2 dependent process (2000) (22)
Phosphorylation of nuclear proteins. (1983) (20)
Roles of importin in nuclear protein import. (1995) (19)
The Fragile Environment: The Darwin College Lectures (1991) (18)
Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae of Xenopus laevis. (1973) (17)
Methods of transplanting nuclei from single cultured cells to unfertilized frogs' eggs. (1970) (17)
Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes. (2016) (17)
Isolation of Stool-Derived Mucus Provides a High Yield of Colonocytes Suitable for Early Detection of Colorectal Carcinoma (2009) (16)
The Fragile environment (1989) (16)
Developmental inactivity of 5S RNA genes persists when chromosomes are cut between genes (1982) (15)
Regulatory Roles of the Nuclear Membrane (1998) (14)
Induction of chromosome replication during maturation of amphibian oocytes. (1983) (14)
In vitro differentiation of a homogeneous cell population--the epidermis of Xenopus laevis. (1975) (14)
Genes (3rd edn): by Benjamin Lewin, John Wiley & Sons, 1987. £33.45/$38.95 (hbk), £16.95/$11.50 (pbk) (xx + 761 pages) ISBN 0 471 8378 2 (1988) (13)
Nuclear structure and the control of DNA replication in the Xenopus embryo (1989) (13)
Sequence Features of the Nucleoplasmin Tail Region and Evidence for a Selective Entry Mechanism for Transport into the Cell Nucleus (1986) (12)
The Cellular Protein MCM3AP Is Required for Inhibition of Cellular DNA Synthesis by the IE86 Protein of Human Cytomegalovirus (2012) (12)
Patterns of DNA replication in Drosophila polytene nuclei replicating in Xenopus egg and oocyte extracts. (1992) (11)
Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells (2012) (11)
MCM3AP Is Transcribed from a Promoter within an Intron of the Overlapping Gene for GANP (2011) (10)
Expression of cloned genes in cell-free systems and in microinjected Xenopus oocytes (1981) (9)
Chromosome replication in early Xenopus embryos. (1985) (6)
Injected amphibian oocytes: a living test tube for the study of eukaryotic gene transcription? (1977) (6)
Replication origins in the xenopus egg (1982) (6)
Minichromosome maintenance proteins in cancer screening. (2009) (6)
ANALYSIS OF CHROMOSOME REPLICATION WITH EGGS OF XENOPUS LAEVIS (1985) (5)
Injected living cells as a biochemical test tube (1977) (5)
The translation of viral RNAs in frog oocytes. (1974) (4)
Intracellular and intercellular cross talk between NGF and TNF. (2011) (4)
CIBA Medal Lecture. Regulatory roles of the nuclear membrane. (1998) (4)
Control of DNA replication in reconstituted nuclei. (1991) (4)
Cdc 6 protein causes premature entry into S phase in a mammalian cell-free system (2013) (3)
The cell nucleus. (1987) (3)
4 Roles of Nuclear Structure in DNA Replication (1996) (3)
25 Cancer Diagnosis and DNA Replication (2006) (3)
Solving Mysteries of DNA Replication and Frog Cloning (2005) (2)
MCM 3 AP , a novel acetyltransferase that acetylates replication protein MCM 3 (2013) (2)
Prospects for Reassembling the Cell Nucleus (1986) (2)
New Minimally Invasive Approaches to Early Cancer Detection (2007) (1)
Almost everything you wanted to know about chromosomes (1981) (1)
Cell cycle: A major transition for embryos and for embryologists (1983) (1)
Vive le replicon! (1982) (1)
Molecular cell biology: by James Darnell, Harvey Lodish and David Baltimore, W. H. Freeman/Scientific American, 1986. £41.95/$42.95 (hbk) £19.95 (pbk) ISBN 0 7167 1448 5 (1986) (0)
Accelerated chromatin replication in embryonic cells (1983) (0)
Higher order structure in the nucleus : proceedings of the first British Society for Cell Biology-Company of Biologists Symposium held in Manchester, April 1984 (1984) (0)
The control of DNA replication in normal and neoplastic cells. (1999) (0)
Eukaryotic chromosome replication : proceedings of a Royal Society discussion meeting held on 10 and 11 December 1986 (1987) (0)
One-night mushrooms (1999) (0)
NUCLEAR TRANSPLANTATION AND GENE INJECTION IN THE ANALYSIS OF AMPHIBIAN DEVELOPMENT (1978) (0)
Replication Replication Proteins and Human Disease (2012) (0)
Roles of Nuclear Structure in DNA Replication (2005) (0)
Abstracts of papers presented at the Mammalian Genetics Group Meeting held in the Society of Antiquaries, Piccadilly, London on 8 November and in the Linnean Society Rooms, Piccadilly, London on the 9 November 1988 (2008) (0)
Music to your ears: The highs and lows of music (2002) (0)
COUPLING DNA REPLICATION TO THE CELL CYCLE (1996) (0)
A Minimally Invasive Approach to the Early Detection of Oral Dysplasia (2005) (0)
Table of Contents (1996) (0)
130 GINS proteins as candidate markers for urine-based cancer screening (2010) (0)
"Developmental Capacity of Nuclei Transplanted from Keratinized Skin Cells of Adult Frogs" (1975), by John Gurdon, Ronald Laskey, and O. Raymond Reeves (2017) (0)
Part 1 of the license (1995) (0)
Book Review:Cloning: Nuclear Transplantation in Amphibia. Robert Gilmore McKinnell (1979) (0)
Cellular update (1989) (0)
Molecular mechanisms of chromatin assembly. (1981) (0)
Processes using the toxin system / bacterial ParD kis antitoxin / ParD kid to kill eukaryotic cells. (2000) (0)
Altered retinoic acid signalling and its relationship to Cdx-2 in Barrett’s oesophagus and associated carcinogenesis (2005) (0)
Retinoic acid-induced glandular differentiation of the oesophagus. Commentary (2007) (0)
Human Papillomavirus Infections : Warts or (2013) (0)
Ron Laskey (2015) (0)
THE MECHANISM OF NUCLEOSOME ASSEMBLY (1979) (0)
Life: Life and death of a cell (2014) (0)
Improved detection of dysplastic and malignant cells in cytological preparations using antibodies against minichromosome maintenance proteins (2000) (0)
Induction of Deoxyribonucleic Acid Synthesis and Chromatin Assembly by Xenopus Egg Cytoplasm (1977) (0)
USE OF BACTERIAL ParD kis / kid ParD TOXIN ANTI TOXIN SYSTEM OF KILLING eukaryotic cells (2000) (0)
Nucleus and gene expression (1989) (0)
Determining an abnormality in cell growth. (1998) (0)
Introduction: The nuclear envelope (1992) (0)
Electrophoresis in the separation of biological macromolecules: Ö. Gaál, G. A. Medgyesi and L. Vereczkey. John Wiley, Chichester, and Akademiai Kiado, Budapest. 1980. 422 pp. £21.00 (1980) (0)
Organisation of the cell nucleus (1995) (0)
The Role of Surface Brushings in the Noninvasive Detection of Laryngeal Dysplasia (2005) (0)
The changing world (1996) (0)

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What Schools Are Affiliated With Ron Laskey?

Ron Laskey is affiliated with the following schools:

University of Cambridge

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