Ronald G. Tompkins
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Engineering Philosophy
Ronald G. Tompkins's Degrees
- Doctorate Medicine Harvard University
Why Is Ronald G. Tompkins Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ronald G. Tompkins was an American physician and academic. He served as Sumner M. Redstone Professor of Surgery at Harvard Medical School and chief of Surgery, Science and Bioengineering at Massachusetts General Hospital’s Division of Surgery. He was also the founding director of The Institute for Bioengineering and Biotechnology and of the Center for Engineering in Medicine & Surgery at MGH.
Ronald G. Tompkins's Published Works
Published Works
- Isolation of rare circulating tumour cells in cancer patients by microchip technology (2007) (3343)
- Genomic responses in mouse models poorly mimic human inflammatory diseases (2013) (2016)
- Continuous inertial focusing, ordering, and separation of particles in microchannels (2007) (1441)
- A network-based analysis of systemic inflammation in humans (2005) (1417)
- Detection of mutations in EGFR in circulating lung-cancer cells. (2008) (1334)
- Common virulence factors for bacterial pathogenicity in plants and animals. (1995) (1281)
- A genomic storm in critically injured humans (2011) (949)
- Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. (1990) (797)
- Hepatocyte function and extracellular matrix geometry: long‐term culture in a sandwich configuration (1989) (719)
- Long‐Term in Vitro Function of Adult Hepatocytes in a Collagen Sandwich Configuration (1991) (687)
- Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing (2010) (622)
- Significance analysis of time course microarray experiments. (2005) (617)
- Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. (1999) (591)
- Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. (2004) (567)
- Objective estimates of the probability of death from burn injuries. (1998) (564)
- American Burn Association Consensus Conference to Define Sepsis and Infection in Burns (2007) (540)
- Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer (2010) (516)
- Support of the metabolic response to burn injury (2004) (453)
- Plants and animals share functionally common bacterial virulence factors. (2000) (422)
- Equilibrium separation and filtration of particles using differential inertial focusing. (2008) (402)
- A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. (2007) (330)
- Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. (1997) (330)
- Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation (1992) (284)
- Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome. (2004) (273)
- Long-term outcome of children surviving massive burns. (2000) (259)
- Application of genome-wide expression analysis to human health and disease. (2005) (240)
- The Association Between Fluid Administration and Outcome Following Major Burn: A Multicenter Study (2007) (234)
- Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass (2003) (233)
- Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function. (1996) (216)
- Whole blood and leukocyte RNA isolation for gene expression analyses. (2004) (209)
- Inhibitors of Pathogen Intercellular Signals as Selective Anti-Infective Compounds (2007) (197)
- Prompt Eschar Excision: A Treatment System Contributing to Reduced Burn Mortality (1986) (188)
- Nucleation and growth of ice crystals inside cultured hepatocytes during freezing in the presence of dimethyl sulfoxide. (1993) (187)
- Significant Reductions in Mortality for Children With Burn Injuries Through the Use of Prompt Eschar Excision (1988) (185)
- The Metabolic Stress Response to Burn Trauma: Current Understanding and Therapies (2016) (178)
- Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes. (2005) (170)
- The Drosophila melanogaster Toll Pathway Participates in Resistance to Infection by the Gram-Negative Human Pathogen Pseudomonas aeruginosa (2003) (160)
- Quantitative Proteome Analysis of Human Plasma following in Vivo Lipopolysaccharide Administration Using 16O/18O Labeling and the Accurate Mass and Time Tag Approach*S (2005) (159)
- Clinical Microfluidics for Neutrophil Genomics and Proteomics (2010) (158)
- Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. (2010) (155)
- Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification (2015) (153)
- Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. (2000) (152)
- Morbidity and Survival Probability in Burn Patients in Modern Burn Care* (2015) (151)
- Temporal Cytokine Profiles in Severely Burned Patients: A Comparison of Adults and Children (2008) (145)
- Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers. (2004) (142)
- Aggressive early crystalloid resuscitation adversely affects outcomes in adult blunt trauma patients: An analysis of the Glue Grant database (2013) (142)
- Oxygen uptake rates in cultured rat hepatocytes. (1992) (138)
- Quantitation of beat-to-beat changes in stroke volume from the aortic pulse contour in man. (1953) (138)
- The Metabolic Basis of the Increase in Energy Expenditure in Severely Burned Patients (1999) (134)
- Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance. (2002) (134)
- Circulating interleukin‐1β and tumor necrosis factor‐α concentrations after burn injury in humans (1992) (129)
- The acutely burned hand: management and outcome based on a ten-year experience with 1047 acute hand burns. (1995) (127)
- The practice of venous thromboembolism prophylaxis in the major trauma patient. (2007) (126)
- The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock* (2012) (125)
- Continuous flow microfluidic device for rapid erythrocyte lysis. (2004) (124)
- Burn Injury Reduces Neutrophil Directional Migration Speed in Microfluidic Devices (2010) (120)
- Objective Estimates of the Probability of Death from Burn Injuries (1998) (120)
- Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice. (1996) (119)
- Dynamics of cell membrane permeability changes at supraphysiological temperatures. (1995) (119)
- Human transcriptome array for high-throughput clinical studies (2011) (115)
- Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry (2005) (114)
- Artificial skin. (2000) (112)
- Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats. (1993) (112)
- Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. (2009) (111)
- Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways (2006) (109)
- Assessment of Artificial Liver Support Technology (1992) (109)
- Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft. (1998) (107)
- Treatment of heterotopic ossification through remote ATP hydrolysis (2014) (107)
- Bone Marrow Mesenchymal Stromal Cells Attenuate Organ Injury Induced by LPS and Burn (2010) (107)
- Increased gut permeability early after burns correlates with the extent of burn injury (1992) (106)
- Nosocomial infections in pediatric patients with burns. (1997) (105)
- Severe Injury Is Associated With Insulin Resistance, Endoplasmic Reticulum Stress Response, and Unfolded Protein Response (2012) (105)
- Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate dermal regeneration. (1995) (105)
- Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. (2004) (102)
- Retrovirus infection: effect of time and target cell number (1995) (101)
- Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes. (1995) (100)
- Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. (2001) (100)
- Early Enteral Nutrition in Burns: Compliance With Guidelines and Associated Outcomes in a Multicenter Study (2011) (98)
- High Dynamic Range Characterization of the Trauma Patient Plasma Proteome*S (2006) (97)
- Burn injury causes mitochondrial dysfunction in skeletal muscle. (2005) (97)
- Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes (1994) (96)
- Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection. (1993) (96)
- American Burn Association/Shriners Hospitals for Children burn outcomes questionnaire: construction and psychometric properties. (2000) (94)
- Early Acute Kidney Injury Predicts Progressive Renal Dysfunction and Higher Mortality in Severely Burned Adults (2010) (93)
- Analysis of Thermal Injury-induced Insulin Resistance in Rodents (1997) (93)
- Current expectations for survival in pediatric burns. (2000) (93)
- Early burn center transfer shortens the length of hospitalization and reduces complications in children with serious burn injuries. (1999) (93)
- Artificial skin in massive burns — results to ten years (1994) (92)
- Preliminary Evidence for the Effects of Morphine on Posttraumatic Stress Disorder Symptoms in One- to Four-Year-Olds With Burns (2009) (92)
- A Genomic Score Prognostic of Outcome in Trauma Patients (2009) (91)
- Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes. (1993) (91)
- A Stable Long‐Term Hepatocyte Culture System for Studies of Physiologic Processes: Cytokine Stimulation of the Acute Phase Response in Rat and Human Hepatocytes (1992) (91)
- Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes. (2005) (91)
- iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53 (2017) (90)
- A Microchip Approach for Practical Label-Free CD4+ T-Cell Counting of HIV-Infected Subjects in Resource-Poor Settings (2007) (90)
- Long-term consequences of toxic epidermal necrolysis in children. (2002) (89)
- Benchmarking Outcomes in the Critically Injured Trauma Patient and the Effect of Implementing Standard Operating Procedures (2012) (88)
- Burn depth estimation by use of indocyanine green fluorescence: initial human trial. (1995) (88)
- Autoradiographic method for quantitation of radiolabeled proteins in tissues using indium-111. (1989) (87)
- A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels. (1992) (87)
- Nitric oxide production is intensely and persistently increased in tissue by thermal injury. (1994) (87)
- Death in the burn unit: sterile multiple organ failure. (1998) (85)
- Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. (2006) (85)
- Development of a Genomic Metric That Can Be Rapidly Used to Predict Clinical Outcome in Severely Injured Trauma Patients* (2013) (84)
- Nonequilibrium freezing of one-cell mouse embryos. Membrane integrity and developmental potential. (1993) (84)
- EARLY ELEVATION IN RANDOM PLASMA IL-6 AFTER SEVERE INJURY IS ASSOCIATED WITH DEVELOPMENT OF ORGAN FAILURE (2010) (84)
- Cultured autologous epithelium in patients with burns of ninety percent or more of the body surface. (1995) (82)
- A 10-year experience with toxic epidermal necrolysis. (2000) (80)
- Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients. (2008) (79)
- Benchmarking Outcomes in the Critically Injured Burn Patient (2014) (78)
- What's new in burns and metabolism. (2004) (77)
- Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. (1998) (76)
- Management of Burn Wounds with Prompt Excision and Immediate Closure (1994) (75)
- Plasma arginine and leucine kinetics and urea production rates in burn patients. (1995) (75)
- Developing Effective Alzheimer’s Disease Therapies: Clinical Experience and Future Directions (2019) (74)
- Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. (2002) (73)
- Permissive hypercapnia as a ventilatory strategy in burned children: effect on barotrauma, pneumonia, and mortality. (1995) (73)
- Cryopreservation of Isolated Primary Rat Hepatocytes: Enhanced Survival and Long-term Hepatospecific Function (2005) (72)
- Antibody-targeted Photolysis of Bacteria In Vivo (1994) (72)
- Transport phenomena during freezing of isolated hepatocytes (1992) (71)
- Acellular allodermis in burns surgery: 1-year results of a pilot trial. (1998) (71)
- The development, validation, and testing of a health outcomes burn questionnaire for infants and children 5 years of age and younger: American Burn Association/Shriners Hospitals for Children. (2002) (71)
- Acute hand burns in children: management and long-term outcome based on a 10-year experience with 698 injured hands. (1999) (70)
- A new approach to the cryopreservation of hepatocytes in a sandwich culture configuration. (1990) (70)
- Mice are not men (2014) (70)
- Emergency management of major hydrofluoric acid exposures. (1995) (70)
- Cutaneous thermal injury alters macromolecular permeability of rat small intestine. (1990) (69)
- Isolation and long-term culture of human hepatocytes. (1993) (69)
- Increased survival after massive thermal injuries in adults: preliminary report using artificial skin. (1989) (68)
- Analysis of factorial time-course microarrays with application to a clinical study of burn injury (2010) (67)
- Initial experience with a composite autologous skin substitute. (2001) (67)
- Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure. (2009) (66)
- In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates. (1993) (65)
- Genomics of injury: The Glue Grant experience. (2015) (64)
- Intestinal Production of Interleukin-1α during Endotoxemia in the Mouse (1993) (63)
- Cellular distribution of endotoxin after injection of chemically purified lipopolysaccharide differs from that after injection of live bacteria. (1994) (63)
- Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit. (1993) (63)
- Spontaneous Neutrophil Migration Patterns during Sepsis after Major Burns (2014) (62)
- Long-Term Functional Recovery of Hepatocytes after Cryopreservation in a Three-Dimensional Culture Configuration* (1992) (62)
- A quantitative model of invasive Pseudomonas infection in burn injury. (1994) (60)
- Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess (2011) (59)
- Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients. (1995) (59)
- Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. (1998) (59)
- Planimetry study of the percent of body surface represented by the hand and palm: sizing irregular burns is more accurately done with the palm. (1995) (58)
- Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts. (1997) (58)
- Dissecting Inflammatory Complications in Critically Injured Patients by Within-Patient Gene Expression Changes: A Longitudinal Clinical Genomics Study (2011) (58)
- Inflammation and the Host Response to Injury: An Overview of the Multicenter Study of the Genomic and Proteomic Response to Burn Injury (2006) (57)
- Long-term posttraumatic stress symptoms vary inversely with early opiate dosing in children recovering from serious burns: Effects durable at 4 years (2014) (56)
- Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. (1994) (56)
- Inhalation Injury in Children: A 10 Year Experience at Shriners Hospitals for Children (2009) (55)
- Management of severe toxic epidermal necrolysis in children. (1999) (55)
- Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans. (2002) (55)
- Quantitative aspects of interorgan relationships among arginine and citrulline metabolism. (1996) (54)
- Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. (1992) (53)
- The metabolic basis of the increase of the increase in energy expenditure in severely burned patients. (1999) (53)
- Central venous catheter sepsis with weekly catheter change in paediatric burn patients: an analysis of 221 catheters. (1995) (53)
- Benchmarks for Multidimensional Recovery After Burn Injury in Young Adults: The Development, Validation, and Testing of the American Burn Association/Shriners Hospitals for Children Young Adult Burn Outcome Questionnaire (2013) (53)
- Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. (2009) (52)
- Cryopreservation of isolated hepatocytes: intracellular ice formation under various chemical and physical conditions. (1991) (52)
- Survival from burns in the new millennium: 70 years' experience from a single institution. (2015) (51)
- Determination of Burn Patient Outcome by Large-Scale Quantitative Discovery Proteomics (2013) (51)
- Bioengineering of liver assist devices. (2002) (51)
- Impact of Oxandrolone Treatment on Acute Outcomes After Severe Burn Injury (2008) (50)
- Development of a pediatric burn pain and anxiety management program. (1997) (50)
- Dynamics of photoinduced cell plasma membrane injury. (1995) (49)
- Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography. (1997) (49)
- Kinetics of plasma arginine and leucine in pediatric burn patients. (1996) (49)
- Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. (2010) (49)
- Optimization of hepatocyte attachment to microcarriers: Importance of oxygen (1993) (48)
- The Quorum Sensing Volatile Molecule 2-Amino Acetophenon Modulates Host Immune Responses in a Manner that Promotes Life with Unwanted Guests (2012) (48)
- Low-dose inhaled nitric oxide in acutely burned children with profound respiratory failure. (1999) (46)
- Recovery Trajectories After Burn Injury in Young Adults: Does Burn Size Matter? (2015) (46)
- Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism. (1997) (45)
- Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation. (2005) (45)
- Effect of burn injury on glucose and nitrogen metabolism in the liver: preliminary studies in a perfused liver system. (1997) (45)
- Mapping of local renal blood flow with PET and H(2)(15)O. (2002) (45)
- Control of methicillin-resistant Staphylococcus aureus in a pediatric burn unit. (1994) (44)
- In vitro and in vivo evaluation of albumin synthesis rate of porcine hepatocytes in a flat-plate bioreactor. (2001) (44)
- Pulmonary artery wedge pressures in mitral valve disease; relationship to left atrial pressures. (1953) (43)
- Human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome. (1994) (42)
- A Fulminant Hepatic Failure Model in the Rat (2001) (42)
- Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation (2016) (42)
- Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure. (2003) (42)
- Novel Mitochondria-Targeted Antioxidant Peptide Ameliorates Burn-Induced Apoptosis and Endoplasmic Reticulum Stress in the Skeletal Muscle of Mice (2011) (41)
- Mild Obesity Is Protective After Severe Burn Injury (2013) (41)
- Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model. (2005) (40)
- Incidence of Catheter-Associated Bloodstream Infection After Introduction of Minocycline and Rifampin Antimicrobial-Coated Catheters in a Pediatric Burn Population (2012) (39)
- Prophylactic antibiotics and their role in the prevention of surgical wound infection. (1994) (39)
- Evaluation of acellular human dermis as a dermal analog in a composite skin graft. (1996) (39)
- Guidelines: Expression profiling — best practices for data generation and interpretation in clinical trials (2004) (39)
- Intracompartmental sepsis in burn patients. (1994) (39)
- Invention, innovation, entrepreneurship in academic medical centers. (2008) (39)
- Redistribution of blood flow after thermal injury and hemorrhagic shock. (1988) (39)
- Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides. (2006) (38)
- Are Topical Antimicrobials Effective Against Bacteria That are Highly Resistant to Systemic Antibiotics? (2009) (38)
- Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier. (1990) (38)
- Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. (1997) (38)
- Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats. (2009) (37)
- Standard Operating Procedures for the Clinical Management of Patients Enrolled in a Prospective Study of Inflammation and the Host Response to Thermal Injury (2007) (37)
- Prediction of multiple infections after severe burn trauma: a prospective cohort study. (2015) (36)
- Progress in burn treatment and the use of artificial skin (1990) (35)
- Abstract 1136: Detection and characterization of circulating tumor cells in localized and metastatic prostate cancer patients using CTC-Chip microfluidic technology (2010) (35)
- Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma. (2000) (35)
- Candidemia in the pediatric patient with burns. (1995) (35)
- Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes. (2006) (35)
- TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections (2016) (34)
- Validation of the Riboleukogram to Detect Ventilator-Associated Pneumonia After Severe Injury (2009) (34)
- Extracorporeal plasma perfusion of cultured hepatocytes: effect of intermittent perfusion on hepatocyte function and morphology. (1996) (34)
- L-ARGININE ATTENUATES ACUTE LUNG INJURY AFTER SMOKE INHALATION AND BURN INJURY IN SHEEP (2007) (34)
- Involvement of Skeletal Muscle Gene Regulatory Network in Susceptibility to Wound Infection Following Trauma (2007) (34)
- Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification. (2017) (34)
- Long-Term Function of Cryopreserved Rat Hepatocytes in a Coculture System (2004) (34)
- Flavobacterial sepsis in massively burned pediatric patients. (1993) (34)
- Inhaled nitric oxide in burn patients with respiratory failure. (1997) (33)
- Adolescent survivors of burn injuries and their parents’ perceptions of recovery outcomes: Do they agree or disagree? (2012) (33)
- The use of pentafluorophenyl derivatives for the 18F labelling of proteins. (1994) (33)
- Long-term maintenance of cytochrome P450 activities by rat hepatocyte/3T3 cell co-cultures in heparinized human plasma. (2001) (33)
- Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue. (2004) (32)
- Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6. (2011) (32)
- Increased transcellular permeability of rat small intestine after thermal injury. (1992) (32)
- Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma‐induced apoptosis (2005) (32)
- Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study. (2004) (32)
- Enzymatic function of alginate immobilized rat hepatocytes (1988) (32)
- Antibody-targeted photolysis. Bacteriocidal effects of Sn (IV) chlorin e6-dextran-monoclonal antibody conjugates. (1991) (32)
- Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice. (2010) (32)
- Differences in Resuscitation in Morbidly Obese Burn Patients May Contribute to High Mortality (2013) (32)
- Burns in children younger than two years of age: an experience with 200 consecutive admissions. (1997) (31)
- Young age is not a predictor of mortality in burns (2001) (31)
- Reversal of Growth Arrest With the Combined Administration of Oxandrolone and Propranolol in Severely Burned Children (2016) (31)
- Management strategy in purpura fulminans with multiple organ failure in children. (1996) (31)
- Inflammation and the host response to injury, a large-scale collaborative project: Patient-oriented research core - Standard operating procedures for clinical care. Foreward (2008) (31)
- Additive effects of thermal injury and infection on gut permeability. (1994) (31)
- Optimization of rat hepatocyte culture in citrated human plasma. (2000) (31)
- Advances in recombinant retroviruses for gene delivery (1993) (30)
- Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver. (1999) (30)
- Strategies for success in academic surgery. (1995) (30)
- Is Real-Time Feedback of Burn-Specific Patient-Reported Outcome Measures in Clinical Settings Practical and Useful? A Pilot Study Implementing the Young Adult Burn Outcome Questionnaire (2016) (30)
- Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients (2015) (30)
- Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans. (1998) (30)
- The effect of family characteristics on the recovery of burn injuries in children (2012) (29)
- Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry. (2005) (29)
- Separation and quantitation of polyethylene glycols 400 and 3350 from human urine by high-performance liquid chromatography. (1992) (29)
- A rabbit model for metabolic studies after burn injury. (1998) (29)
- Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O. (2002) (29)
- Midazolam infusion in pediatric patients with burns who are undergoing mechanical ventilation. (1994) (29)
- Staphylococcal toxic shock syndrome in a paediatric burn unit. (1994) (29)
- Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology (2011) (29)
- Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism. (2013) (29)
- Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. (2009) (29)
- Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. (2008) (29)
- Effects of dimethyl sulfoxide on cultured rat hepatocytes in sandwich configuration. (1992) (29)
- Selective Activation of Peripheral Blood T Cell Subsets by Endotoxin Infusion in Healthy Human Subjects Corresponds to Differential Chemokine Activation1 (2005) (28)
- Impact of hand burns on health-related quality of life in children younger than 5 years (2012) (28)
- A Small Volatile Bacterial Molecule Triggers Mitochondrial Dysfunction in Murine Skeletal Muscle (2013) (28)
- Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. (1996) (28)
- Spatial distribution of tumor-specific monoclonal antibodies in human melanoma xenografts. (1992) (28)
- Cutaneous herpetic infections complicating burns. (2000) (27)
- Improved Management of the Perineal Wound after Prootectomy (1985) (27)
- The role of proinflammatory cytokines in inflammatory and metabolic responses. (1997) (27)
- The American Burn Association/Shriners Hospitals for Children Burn Outcomes Program: A progress report at 15 years (2012) (27)
- Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting by GTS-21, a Specific Agonist for &agr;7 Nicotinic Acetylcholine Receptors (2017) (27)
- Low-density lipoprotein transport in blood vessel walls of squirrel monkeys. (1989) (26)
- Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo. (2011) (26)
- Recovery Curves for Pediatric Burn Survivors: Advances in Patient-Oriented Outcomes. (2016) (26)
- Immobilized IL-2 preserves the viability of an IL-2 dependent cell line. (1993) (26)
- Acute adrenal insufficiency in the burn intensive care unit. (1993) (26)
- Energy and protein provisions for thermally injured children revisited: an outcome-based approach for determining requirements. (1997) (26)
- A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats. (2007) (26)
- Effectiveness of Bacteria-Controlled Nursing Units in Preventing Cross-Colonization With Resistant Bacteria in Severely Burned Children (2002) (26)
- Simvastatin reduces burn injury-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway. (2015) (26)
- Quantitative analysis of blood vessel permeability of squirrel monkeys. (1991) (25)
- Tunable dye laser neovessel ablation as an adjunct to the management of hypertrophic scarring in burned children: pilot trial to establish safety. (1997) (25)
- Antibiotic prophylaxis for group A streptococcal burn wound infection is not necessary. (2001) (25)
- Preparation and characterization of immunoconjugates for antibody-targeted photolysis. (1990) (25)
- Title efficacy of phosphodiesterase 5 inhibitor on distant burn-induced muscle autophagy, microcirculation, and survival rate. (2013) (25)
- Comparative evaluation of the quantitative utilization of parenterally and enterally administered leucine and L-[1-13C,15N]leucine within the whole body and the splanchnic region. (1995) (25)
- Ice Formation in Isolated Human Hepatocytes and Human Liver Tissue (1997) (24)
- Thermal injury in rats alters glucose utilization by skin, wound, and small intestine, but not by skeletal muscle. (1996) (24)
- The burn unit as a resource for the management of acute nonburn conditions in children. (1995) (24)
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- Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2 (2016) (18)
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- A 15-year experience with varicella infections in a pediatric burn unit. (1999) (17)
- Thermal injury-induced changes in the rat intestine brush border cytoskeleton. (1993) (17)
- Adipocyte Apoptosis After Burn Injury Is Associated With Altered Fat Metabolism (2006) (17)
- Percutaneous cholecystostomy in the critically ill burn patient. (1995) (17)
- Role of β1 Integrin Distribution in Morphology and Function of Collagen-Sandwiched Hepatocytes (1997) (17)
- The Glue Grant experience: characterizing the post injury genomic response (2011) (17)
- Role of Protein Farnesylation in Burn-Induced Metabolic Derangements and Insulin Resistance in Mouse Skeletal Muscle (2015) (16)
- The activity of cytochrome P450IA1 in stable cultured rat hepatocytes. (1995) (16)
- Coenzyme Q10 protects against burn‐induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle (2019) (16)
- Platelet transfusion increases risk for acute respiratory distress syndrome in non-massively transfused blunt trauma patients (2019) (16)
- Trauma‐associated human neutrophil alterations revealed by comparative proteomics profiling (2013) (15)
- Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma. (2008) (15)
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- Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis (2020) (14)
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- Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn. (2008) (14)
- Detection of acute bacterial infection within soft tissue injuries using a 99mTc-labeled chemotactic peptide. (1995) (14)
- Corrigendum: A network-based analysis of systemic inflammation in humans (2005) (14)
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- Application of Materials in Medicine and Dentistry (1996) (13)
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- Intraoperative reflectance oximetry in burn patients (2005) (11)
- Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport. (2003) (11)
- Expression of Long-Term Liver-Specific Function by Adult Rat Hepatocytes Cultured on Microcarriers (1997) (11)
- Femoral arterial catheterization in paediatric burn patients. (1994) (11)
- Simvastatin Protects Hepatocytes From Apoptosis by Suppressing the TNF-&agr;/Caspase-3 Signaling Pathway in Mice With Burn Injury (2013) (11)
- Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance. (2010) (11)
- An ALPHA7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice (2017) (11)
- Pluripotent stem cell derived hepatocytes : using materials to define cellular differentiation and tissue engineering (2016) (11)
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- Role of Elevated Fibrinogen in Burn-Induced Mitochondrial Dysfunction: Protective Effects of Glycyrrhizin (2016) (10)
- A Simple Cost-Saving Measure: 2.5% Mafenide Acetate Solution (2014) (10)
- Rectal necrosis after pelvic crush injury. (1988) (10)
- Evaluation of Intragastric Vs Intraperitoneal Glucose Tolerance Tests in the Evaluation of Insulin Resistance in a Rodent Model of Burn Injury and Glucagon-Like Polypeptide-1 Treatment (2014) (10)
- A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro). (2005) (10)
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- Bacterial cell killing by antibody targeted photolysis : enhanced effect by OH radical generation (1994) (6)
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- In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in trauma (2010) (2)
- Gram-Negative Bacterial Infection in Thigh Abscess Can Migrate to Distant Burn Depending on Burn Depth (2012) (2)
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- Regional in vitro uptake of a synthetic 3H-labeled-melanin into rat brain (1977) (1)
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- WHAT ’ S NEW IN SURGERY What ’ s New in Burns and Metabolism (2004) (1)
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- 1686: MEGAKARYOCYTES ARE FUNCTIONAL INNATE IMMUNE CELLS AND MAY PLAY A ROLE IN SEPSIS (2020) (1)
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- Burn induced changes in cerebral and myocardial glucose metabolism in rodents (2009) (1)
- Muscle protein synthesis by positron-emission tomography with L-[ methyl-11 C ] methionine in adult humans ( skeletal muscle y fractional synthesis rate ) (1998) (1)
- Herpetic Infection in Burn Patients: 157. (1998) (1)
- Burn injury differentially alters whole-blood and organ glutathione synthesis rates: An experimental model (2013) (1)
- Effect of Exercise on Burn-Induced Changes in Tissue-Specific Glucose Metabolism (2014) (1)
- Cryopreservation of hepatocytes: Initial experience with an improved technique to maintain long-term hepatocyte function☆ (1989) (1)
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- 349: INTERLEUKIN-6 PREDICTS ACUTE RESPIRATORY DISTRESS SYNDROME IN ADULTS WITH SEVERE BLUNT TRAUMA (2013) (1)
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- 31P NMR demonstrates reduced ATP synthesis rate and concomitant downregulation of PGC-1β mitochondrial gene expression in skeletal muscle after burn injury (2009) (1)
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- SYNOPSES BY TECHNOLOGY Genomics/Microarray, Proteomics, RNAi, ChIP-chip GENOMICS/MICROARRAY (2005) (0)
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- In vivo measurements of whole body (WB) and skeletal muscle glucose metabolism under basal and euglycemic insulin clamp (Clamp) by combined PET and stable isotope (SI) tracer studies (2007) (0)
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- FDG uptake by brown adipose tissue (BAT) after cold stress (CS), dermal wound (DW) and burn injury (BI) is associated with increased thermogenesis (2007) (0)
- Ethanol and LPS stimulation of 18F FHBG uptake by lung and heart of NF Kappa B TK transgenic mice (2010) (0)
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- Effects of chronic cold-stress on FDG uptake by brown adipose tissue (BAT) and brain (2008) (0)
- Effects of supraphysiological temperatures on the plasma membrane of isolated skeletal muscle cells (1993) (0)
- Single Hind Limb Burn Injury to Mice Alters Nuclear Factor-&kgr;B Expression and [18F] 2-Fluoro-2-Deoxy-D-Glucose Uptake (2014) (0)
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- Long Term Consequences of Toxic Epidermal Necrolysis In Children: 203. (2001) (0)
- Burn injury increases myocardial uptake of FDG and BFPET but not CardioPET in mice (2011) (0)
- The Impact of Burn Injury on in vivo Whole Blood Glutathione Kinetics: 27. (2000) (0)
- PROTEOMICS – Clinical Applications Table of Contents (2013) (0)
- Imaging of mouse embryonic stem cells (ESC's) delivered to a burn wound surface via Integra scaffolding (2011) (0)
- Early Changes in Leukocyte Gene-Expression Underlie Increased Mortality Associated with Burn Size but Not Age or Inhalation Injury (2014) (0)
- Impairment of insulin-stimulated glucose utilization is associated with burn-induced insulin resistance in mouse muscle by hyperinsulinemic-isoglycemic clamp (2020) (0)
- Combination of radiation and burn injury alters FDG uptake in mice (2008) (0)
- 111In-oxine leukocyte labeling: Intraindividual comparison of leukocyte isolation methods: Conventional versus automated microfluidic chip (2012) (0)
- Post-Translational Modification Profiling of Burn-Induced — Insulin Resistance and Muscle Wasting (2013) (0)
- The Effectiveness of Bacteria Controlled Nursing Units in Preventing Cross Colonization With Resistant Bacteria in Severely Burned Pediatric Patients: 176. (2001) (0)
- 1688: MEGAKARYOCYTES AND PLATELETS MAY BE A SOURCE OF EXTRACELLULAR HISTONES DURING SEPSIS (2020) (0)
- Chapter 32 – Etiology and prevention of multisystem organ failure (2007) (0)
- Chapter 31 – Etiology and prevention of multisystem organ failure (2012) (0)
- Abstracts of the 41st Annual Meeting of the American Burn Association, March 24-27, 2009, San Antonio, Texas, USA. (2009) (0)
- antioxidant therapy defense after burn injury: the beneficial effects of Cardiac mitochondrial damage and loss of ROS (2015) (0)
- Magnetic resonance imaging of c-fos gene transcription after burn trauma using a superior contrast agent (2010) (0)
- PS-208-5 Evolution of Carvon, Nitrogen, and Energy Metabolism in Liver after D-Galactosamine-induced Fulminant Hepatic Failure in Rats (2004) (0)
- Ethanol administration to mice decreases myocardial accumulation of CardioPET and BFPET (2011) (0)
- Young Age Is Not A Predictor of Mortality in Burns: 152. (2000) (0)
- Burn injury stimulates NF kappa B (NF-{kappa}B) expression: Effect of injury extent (2008) (0)
- Erratum to: Physical Rehabilitation and Mental Health Care After Burn Injury: A Multinational Study (2022) (0)
- Patterns and Effects of Fluid Resuscitation in a Prospective Multicenter Clinical Trial: 57. (2006) (0)
- Role of the Sodium Pump (Na,K-ATPase) in Burn Hypermetabolism: 153. (2001) (0)
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