Ronald J. Quinn
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Engineering Computer Science
Ronald J. Quinn's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Ronald J. Quinn's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The re-emergence of natural products for drug discovery in the genomics era (2015) (1720)
- Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors. (2009) (421)
- Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond (2016) (324)
- Adenosine receptors: new opportunities for future drugs. (1998) (269)
- Maculotoxin: a neurotoxin from the venom glands of the octopus Hapalochlaena maculosa identified as tetrodotoxin. (1978) (199)
- Elicitation of secondary metabolism in actinomycetes. (2015) (183)
- Flinderoles A-C: antimalarial bis-indole alkaloids from Flindersia species. (2009) (165)
- Developing a drug-like natural product library. (2008) (160)
- Drug-like properties: guiding principles for the design of natural product libraries. (2012) (143)
- Phospholipase A2 in cnidaria. (2004) (141)
- Dereplication Strategies for Targeted Isolation of New Antitrypanosomal Actinosporins A and B from a Marine Sponge Associated-Actinokineospora sp. EG49 (2014) (130)
- The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer (2014) (117)
- Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163 (2014) (108)
- Axinellamines A-D, Novel Imidazo-Azolo-Imidazole Alkaloids from the Australian Marine Sponge Axinella sp. (1999) (107)
- Direct Screening of Natural Product Extracts Using Mass Spectrometry (2008) (107)
- Biodiversity ‘hotspots’, patterns of richness and endemism, and taxonomic affinities of tropical Australian sponges (Porifera) (2002) (106)
- Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections. (2017) (91)
- Natural products, stylissadines A and B, specific antagonists of the P2X7 receptor, an important inflammatory target. (2007) (89)
- Dysinosin A: a novel inhibitor of Factor VIIa and thrombin from a new genus and species of Australian sponge of the family Dysideidae. (2002) (82)
- Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes (2014) (80)
- Actinophyllic acid, a potent indole alkaloid inhibitor of the coupled enzyme assay carboxypeptidase u/hippuricase from the leaves of Alstonia actinophylla (Apocynaceae). (2005) (79)
- Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia. (2009) (76)
- Natural products as lead structures: chemical transformations to create lead-like libraries. (2014) (75)
- Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis (2014) (74)
- Aplysinopsin, a new tryptophan derivative from a sponge (1977) (73)
- Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae). (2014) (73)
- A new class of halogenated lactones from the red alga (bonnemaisoniaceae) (1977) (69)
- The Relationship between Fenestrations, Sieve Plates and Rafts in Liver Sinusoidal Endothelial Cells (2012) (67)
- The occurrence of prostaglandins PGE2 and PGF2α in a plant - the red alga . (1979) (66)
- The Resveratrol Tetramer (-)-Hopeaphenol Inhibits Type III Secretion in the Gram-Negative Pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa (2013) (65)
- Revised structure of palau'amine (2007) (65)
- Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. (2012) (64)
- Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs. (2011) (64)
- Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa. (2008) (63)
- Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp. (2010) (62)
- Aging biology and novel targets for drug discovery. (2012) (61)
- (+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp. (2010) (60)
- Structural Insights into the Molecular Basis of the Ligand Promiscuity (2012) (60)
- Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita. (2013) (58)
- Dysinosins B-D, inhibitors of factor VIIa and thrombin from the Australian sponge Lamellodysidea chlorea. (2004) (58)
- Psammaplysin H, a new antimalarial bromotyrosine alkaloid from a marine sponge of the genus Pseudoceratina. (2011) (56)
- A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. (2006) (55)
- Harnessing the Properties of Natural Products. (2018) (55)
- Low-Dose Curcumin Stimulates Proliferation, Migration and Phagocytic Activity of Olfactory Ensheathing Cells (2014) (55)
- Native Mass Spectrometry in Fragment-Based Drug Discovery (2016) (55)
- Vanillic acid derivatives from the green algae Cladophora socialis as potent protein tyrosine phosphatase 1B inhibitors. (2007) (54)
- Natural products and the search for novel vaccine adjuvants. (2011) (53)
- Characterization of the neurotoxic constituents of Conus geographus (L) venom. (1977) (53)
- Potential of marine natural products against drug-resistant bacterial infections. (2019) (51)
- Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras. (2009) (49)
- Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target. (2007) (49)
- NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease** (2014) (49)
- Heteronemin, a new scalarin type sesterterpene from the sponge (1976) (49)
- Exiguaquinol: a novel pentacyclic hydroquinone from Neopetrosia exigua that inhibits Helicobacter pylori MurI. (2008) (46)
- Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp. (2010) (46)
- Euodenine A: a small-molecule agonist of human TLR4. (2014) (46)
- Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp. (2011) (44)
- New laurene derivatives from Laurencia filiformis (1976) (44)
- Capturing Nature's Diversity (2015) (43)
- Determination of analyte concentration using the residual solvent resonance in (1)H NMR spectroscopy. (2008) (43)
- Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry (2018) (42)
- Predicting natural product value, an exploration of anti-TB drug space. (2014) (42)
- Aplysamine 6, an alkaloidal inhibitor of Isoprenylcysteine carboxyl methyltransferase from the sponge Pseudoceratina sp. (2008) (42)
- Cheilanthane sesterterpenes, protein kinase inhibitors, from a marine sponge of the genus Ircinia. (2001) (41)
- Anhydride modified cantharidin analogues. Is ring opening important in the inhibition of protein phosphatase 2A? (2000) (41)
- Isolation of psammaplin A 11'-sulfate and bisaprasin 11'-sulfate from the marine sponge Aplysinella rhax. (2000) (40)
- Guiding principles for natural product drug discovery. (2012) (39)
- Anticancer activity of zoanthids and the associated toxin, palytoxin, against Ehrlich ascites tumor and P-388 lymphocytic leukemia in mice. (1974) (39)
- Grandisine A and B, novel indolizidine alkaloids with human delta-opioid receptor binding affinity from the leaves of the Australian rainforest tree Elaeocarpus grandis. (2005) (38)
- TCM, brain function and drug space. (2016) (38)
- Identification of Protein Fold Topology Shared between Different Folds Inhibited by Natural Products (2007) (37)
- A brominated bisacetylenic acid from the marine sponge Xestospongia testudinaria (1985) (37)
- Cytotoxic cardenolides from the latex of Calotropis procera. (2015) (37)
- 1,2-bis(1H-indol-3-yl)ethane-1,2-dione, an indole alkaloid from the marine sponge Smenospongia sp. (2002) (37)
- Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies (2021) (36)
- Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine. (1991) (36)
- Endiandrin A, a potent glucocorticoid receptor binder isolated from the Australian plant Endiandra anthropophagorum. (2007) (35)
- Prunolides A, B, and C: Novel Tetraphenolic Bis-Spiroketals from the Australian Ascidian Synoicum prunum. (1999) (34)
- The conserved acid binding domain model of inhibitors of protein phosphatases 1 and 2A: Molecular modelling aspects. (1993) (34)
- Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens. (1999) (34)
- Petrosamine B, an inhibitor of the Helicobacter pylori enzyme aspartyl semialdehyde dehydrogenase from the Australian sponge Oceanapia sp. (2005) (34)
- 1-Methylisoguanosine, a pharmacologically active agent from a marine sponge (1980) (34)
- Antitrypanosomal pyridoacridine alkaloids from the Australian ascidian Polysyncraton echinatum (2010) (34)
- Lepadins F-H, new cis-decahydroquinoline alkaloids from the Australian ascidian Aplidium tabascum. (2002) (34)
- Polyoxygenated dysidea sterols that inhibit the binding of [I125] IL-8 to the human recombinant IL-8 receptor type A. (2000) (34)
- Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. (2012) (34)
- Two new antioxidant actinosporin analogues from the calcium alginate beads culture of sponge-associated Actinokineospora sp. strain EG49. (2014) (33)
- Inhibition of protein phosphatase 2A by cantharidin analogues (1996) (33)
- Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata. (2009) (33)
- Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. (2019) (32)
- Thrombin inhibitors from the freshwater cyanobacterium Anabaena compacta. (2012) (32)
- Plasmodium gametocyte inhibition identified from a natural-product-based fragment library. (2013) (32)
- Synthesis of four novel natural product inspired scaffolds for drug discovery. (2009) (31)
- Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins (2014) (31)
- Cytotoxic cyclic depsipeptides from the Australian marine sponge Neamphius huxleyi. (2012) (31)
- Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa. (2011) (31)
- Myrtucommulones F-I, phloroglucinols with thyrotropin-releasing hormone receptor-2 binding affinity from the seeds of Corymbia scabrida. (2008) (30)
- Stimulation of guinea-pig brain adenylate cyclase by adneosine analogues with potent pharmacological activity in vivo. (1980) (30)
- Eudistomin V, a New β-Carboline from the Australian Ascidian Pseudodistoma aureum (1998) (30)
- Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists. (1996) (29)
- Design and synthesis of screening libraries based on the muurolane natural product scaffold. (2012) (29)
- 7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata. (2010) (29)
- Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth (2014) (28)
- Acutangulosides A-F, monodesmosidic saponins from the bark of Barringtonia acutangula. (2005) (28)
- Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa. (2013) (28)
- Actinomycete Metabolome Induction/Suppression with N-Acetylglucosamine. (2017) (27)
- Stimulating the proliferation, migration and lamellipodia of Schwann cells using low-dose curcumin (2016) (26)
- A bastadin with potent and selective delta-opioid receptor binding affinity from the Australian sponge Ianthella flabelliformis. (2010) (26)
- Hasubanan alkaloids with delta-opioid binding affinity from the aerial parts of Stephania japonica. (2010) (25)
- Further Acetylenic Acids from the Marine Sponge Xestospongia testudinaria (1991) (25)
- Phospholipase A2 in porifera. (2004) (25)
- Alkaloids from the Chinese vine Gnetum montanum. (2011) (25)
- The Synthesis of a Combinatorial Library Using a Tambjamine Natural Product Template (2001) (24)
- Trikentramides A-D, indole alkaloids from the Australian sponge Trikentrion flabelliforme. (2013) (24)
- A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein (2021) (24)
- Front‐Loading Natural‐Product‐Screening Libraries for log P: Background, Development, and Implementation (2013) (24)
- Hepatitis C Virus NS3 Protease and Helicase Inhibitors from Red Sea Sponge (Amphimedon) Species in Green Synthesized Silver Nanoparticles Assisted by in Silico Modeling and Metabolic Profiling (2020) (24)
- Small-molecule inhibitors of the cancer target, isoprenylcysteine carboxyl methyltransferase, from Hovea parvicalyx. (2008) (23)
- Scaffold Flatness: Reversing the Trend (2013) (23)
- The three binding domain model of adenosine receptors: molecular modeling aspects. (1992) (23)
- Comprehensive TCM molecular networking based on MS/MS in silico spectra with integration of virtual screening and affinity MS screening for discovering functional ligands from natural herbs (2019) (23)
- Alkaloids from the Australian rainforest tree Ochrosia moorei. (2008) (23)
- Polydiscamides B-D from a marine sponge Ircinia sp. as potent human sensory neuron-specific G protein coupled receptor agonists. (2008) (22)
- Niphatoxin C, a cytotoxic tripyridine alkaloid from Callyspongia sp. (2007) (22)
- NMR spectral assignments of a new chlorotryptamine alkaloid and its analogues from Acacia confusa (2007) (22)
- A robust clustering approach for NMR spectra of natural product extracts (2005) (22)
- Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp. (2012) (21)
- Pseudoceratinazole A: a novel bromotyrosine alkaloid from the Australian sponge Pseudoceratina sp (2010) (21)
- Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components (2020) (21)
- Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein (2019) (21)
- Isolation and Total Synthesis of Stolonines A–C, Unique Taurine Amides from the Australian Marine Tunicate Cnemidocarpa stolonifera (2015) (21)
- Botryllamides K and L, new tyrosine derivatives from the Australian ascidian Aplidium altarium (2010) (20)
- Psammaplysenes C and D, cytotoxic alkaloids from Psammoclemma sp. (2007) (20)
- Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp. (1999) (20)
- Tyrosinase inhibitory properties of phenylpropanoid glycosides and flavonoids from Teucrium polium L. var. gnaphalodes (2016) (20)
- Chemical investigation of an antimalarial Chinese medicinal herb Picrorhiza scrophulariiflora. (2013) (20)
- Eco-taxonomic insights into actinomycete symbionts of termites for discovery of novel bioactive compounds. (2015) (19)
- A systems approach using OSMAC, Log P and NMR fingerprinting: An approach to novelty (2017) (19)
- Structure Determination of Pentacyclic Pyridoacridine Alkaloids from the Australian Marine Organisms Ancorina geodides and Cnemidocarpa stolonifera (2014) (19)
- Identification of a New α-Synuclein Aggregation Inhibitor via Mass Spectrometry-based Screening. (2019) (19)
- Fluorine Is a Major Constituent of the Marine Sponge Halichondria moorei (1979) (19)
- Total synthesis of thiaplakortone a: derivatives as metabolically stable leads for the treatment of malaria. (2014) (19)
- The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research (2018) (19)
- Latifolians A and B, novel JNK3 kinase inhibitors from the Papua New Guinean plant Gnetum latifolium. (2005) (19)
- Australian biodiversity via its plants and marine organisms. A high-throughput screening approach to drug discovery (2002) (19)
- Fragment-based screening with natural products for novel anti-parasitic disease drug discovery (2019) (19)
- A new quinoline epoxide from the Australian plant Drummondita calida. (2011) (18)
- Potent Cytotoxic Peptides from the Australian Marine Sponge Pipestela candelabra (2014) (18)
- Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian Aplidium caelestis. (2010) (18)
- Chemical Constituents of Kino Extract from Corymbia torelliana (2014) (18)
- Identification of natural products as novel ligands for the human 5-HT2C receptor (2018) (18)
- (-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata. (2009) (18)
- Optimization of Electrospray Ionization by Statistical Design of Experiments and Response Surface Methodology: Protein–Ligand Equilibrium Dissociation Constant Determinations (2016) (18)
- Evaluation of fermentation conditions triggering increased antibacterial activity from a near-shore marine intertidal environment-associated Streptomyces species (2016) (18)
- Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery (2020) (17)
- Synthesis of 5-methylfuro[3,2-c]quinolin-4(5H)-one via palladium-catalysed cyclisation of N-(2-iodophenyl)-N-methyl-3-furamide (2006) (17)
- Nature Bank and the Queensland Compound Library: unique international resources at the Eskitis Institute for Drug Discovery. (2014) (17)
- Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold. (2015) (17)
- Prenylated dihydrochalcones from Boronia bipinnata that inhibit the malarial parasite enzyme target hemoglobinase II. (2008) (17)
- Chemistry of Aqueous Marine Extracts: Isolation Techniques (1988) (17)
- Tropane alkaloids from Darlingia darlingiana (1999) (16)
- 1-Phenylpyrazolo[3,4-d]pyrimidines; structure-ac:tivity relationships for C6 substituents at A1 and A2A adenosine receptors. (2000) (16)
- Tyrosyl-DNA Phosphodiesterase I Inhibitors from the Australian Plant Macropteranthes leichhardtii. (2015) (16)
- Bioaffinity Mass Spectrometry Screening (2016) (16)
- Achyrodimer F, a tyrosyl-DNA phosphodiesterase I inhibitor from an Australian fungus of the family Cortinariaceae. (2017) (16)
- Synthesis of novel molecular probes inspired by harringtonolide. (2011) (16)
- Hippurin-1, an unusual steroid from the gorginian Isis hippuris (1977) (16)
- Perspicamides A and B, quinolinecarboxylic acid derivatives from the Australian ascidian Botrylloides perspicuum. (2005) (16)
- Naturally occurring cembranes from an Australian sarcophyton species. (2002) (16)
- Ianthesine E, a new bromotyrosine-derived metabolite from the Great Barrier Reef sponge Pseudoceratina sp. (2008) (15)
- An alternative computer model of the 3-dimensional structural of microcystin-LR and nodularin rationalising their interactions with protein phosphatases 1 and 2A (1992) (15)
- Cytotoxic evaluation of alkaloids and isoflavonoids from the Australian tree Erythrina vespertilio. (2012) (15)
- Two polyhalogenated monoterpenes from the red alga plocamium costatum (1976) (15)
- Aplysinellamides A-C, bromotyrosine-derived metabolites from an Australian Aplysinella sp. marine sponge. (2014) (14)
- Genome-Inspired Chemical Exploration of Marine Fungus Aspergillus fumigatus MF071 (2020) (14)
- Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry (2020) (14)
- Inhibition of protein phosphatase 2A by cyclic peptides modelled on the microcystin ring (1996) (14)
- A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson's Disease. (2016) (14)
- Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity (2016) (14)
- Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134 (2019) (14)
- Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method (2021) (13)
- Synthesis of melicodenines C, D and E (2012) (13)
- New galloylated flavanonols from the Australian plant Glochidion sumatranum. (2010) (13)
- Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems. (2014) (13)
- Lipoxygenase inhibitors from the latex of Calotropis Procera (2016) (13)
- Total synthesis of clavatadine A. (2015) (13)
- 1-Phenylpyrazolo[3,4-d]pyrimidines as adenosine antagonists: the effects of substituents at C4 and C6. (1997) (13)
- Mono-α-carbamoylethylthio-substituted pyrazolo[3,4-d]pyrimidines: The position of substitution (1991) (13)
- Native Mass Spectrometry for the Study of PROTAC GNE‐987‐Containing Ternary Complexes (2021) (13)
- Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134 (2020) (13)
- Chemical investigation of drug-like compounds from the Australian tree, Neolitseadealbata. (2010) (12)
- 10-Hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant triunia erythrocarpa. (2000) (12)
- Testicular Caspase-3 and β-Catenin Regulators Predicted via Comparative Metabolomics and Docking Studies (2020) (12)
- Guttiferones O and P, prenylated benzophenone MAPKAPK-2 inhibitors from Garcinia solomonensis. (2009) (12)
- High‐throughput screening in natural product drug discovery in Australia utilising Australia's biodiversity (1999) (12)
- LAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint Analysis. (2015) (12)
- Cytotoxic agarofurans from the seeds of the Australian rainforest vine Celastrus subspicata (2009) (12)
- ApoE secretion modulating bromotyrosine derivative from the Australian marine sponge Callyspongia sp. (2014) (12)
- Dereplication of antioxidant compounds in Bene (Pistacia atlantica subsp. mutica) hull using a multiplex approach of HPLC-DAD, LC-MS and (1)H NMR techniques. (2016) (12)
- Lignans from the Australian Endemic Plant Austrobaileya scandens. (2016) (12)
- Design and Synthesis of Natural Product Inspired Libraries Based on the Three-Dimensional (3D) Cedrane Scaffold: Toward the Exploration of 3D Biological Space. (2018) (12)
- The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis (2015) (11)
- Cytotoxic ethnic Yao medicine Baizuan, leaves of Schisandra viridis A. C. Smith. (2016) (11)
- ent-Labdane diterpenes from the stems of Mallotus japonicus. (2013) (11)
- Spongian diterpenes with thyrotropin releasing hormone receptor 2 binding affinity from Spongia sp. (2008) (11)
- A computer generated model of adenosine receptors rationalising binding and selectivity of receptor ligands (1991) (11)
- Synthesis of antitrypanosomal 1,2-dioxane derivatives based on a natural product scaffold. (2011) (11)
- A Grand Challenge. 2. Phenotypic Profiling of a Natural Product Library on Parkinson's Patient-Derived Cells. (2016) (11)
- The Identification of Bioactive Natural Products by High Throughput Screening (HTS) (2010) (10)
- Kororamide B, a brominated alkaloid from the bryozoan Amathia tortuosa and its effects on Parkinson's disease cells (2015) (10)
- Corymbones A and B, phloroglucinols with thyrotropin releasing hormone receptor 2 binding affinity from the flowers of Corymbia peltata. (2008) (10)
- NMR fingerprints, an integrated approach to uncover the unique components of the drug-like natural product metabolome of termite gut-associated Streptomyces species (2015) (10)
- High-Pressure Synthesis of Enantiomerically Pure C-6 Substituted Pyrazolo[3,4-d]pyrimidines (2001) (10)
- Similarity between Flavonoid Biosynthetic Enzymes and Flavonoid Protein Targets Captured by Three-Dimensional Computing Approach (2015) (10)
- Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F. (2016) (10)
- Dereplication of cytotoxic compounds from different parts of Sophora pachycarpa using an integrated method of HPLC, LC-MS and 1H-NMR techniques (2017) (10)
- Adociasulfate-9, a New Hexaprenoid Hydroquinone from the Great Barrier Reef Sponge Adocia aculeata (1999) (10)
- Tetradehydrofurospongin-1, a new C-21 furanoterpene from a sponge (1976) (9)
- Merosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis Disease (2016) (9)
- Chemoinformatic Analysis as a Tool for Prioritization of Trypanocidal Marine Derived Lead Compounds (2014) (9)
- Critical micelle concentration and hemolytic activity--a correlation suggested by the marine sterol, halistanol trisulfate. (1992) (9)
- Analysis of Approaches to Anti-tuberculosis Compounds (2020) (9)
- A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466 (2020) (9)
- Development of a target identification approach using native mass spectrometry (2021) (9)
- R-(-)-beta-O-methylsynephrine, a natural product, inhibits VEGF-induced angiogenesis in vitro and in vivo. (2010) (9)
- ISOLATION AND SYNTHESIS OF 1-METHYLISOGUANOSINE, A POTENT PHARMACOLOGICALLY ACTIVE CONSTITUENT FROM THE MARINE SPONGE TEDANIA DIGITATA (1980) (9)
- Pyrazolo[3,4-d]pyrimidine analogues of isoguanine (1991) (9)
- Synthesis of cyclic peptides modelled on the microcystin and nodularin rings (1996) (9)
- A study of the binding requirements of calyculin A and dephosphonocalyculin A with PP1, development of a molecular recognition model for the binding interactions of the okadaic acid class of compounds with PP1. (2015) (9)
- Synthesis of 2-substituted pyrazolo[3,4-d]pyrimidines (1991) (8)
- Lysianadioic acid, a carboxypeptidase B inhibitor from Lysiana subfalcata. (2008) (8)
- Isomers of a marine diterpene distinguish sublines of human melanoma cells on the basis of apoptosis, cell cycle arrest and differentiation markers (1992) (8)
- Tyrosine kinase inhibitors from the rainforest tree Polyscias murrayi. (2005) (8)
- Anthoptilides A-E, new Briarane diterpenes from the Australian sea pen Anthoptilum cf. kukenthali. (2000) (8)
- Pyrazolo[3,4-d]pyrimidines; adenosine receptor selectivity (1995) (8)
- The role of arginine in interactions of microcystins with protein phosphatases 1 and 2a (1992) (8)
- Two new unsymmetrically oxygenated C21 furanoterpenes from a sponge (1976) (8)
- Pim2 inhibitors from the Papua New Guinean plant Cupaniopsis macropetala. (2008) (7)
- A model to predict anti-tuberculosis activity: value proposition for marine microorganisms (2016) (7)
- Binding Studies of the Prodrug HAO472 to SARS-Cov-2 Nsp9 and Variants (2022) (7)
- TETRODOTOXIN IN THE BLUE‐RINGED OCTOPUS (1978) (7)
- Aporphine Alkaloids from the Chinese Tree Neolitsea Aurata Var. Paraciculata (2007) (7)
- Two new sesterterpene lactones from a sponge (1976) (7)
- Reversible depigmentation of human melanoma cells by halistanol trisulphate, a novel marine sterol (1992) (7)
- Cyclopentylamine substituted triazolo[4,5-d]pyrimidine: implications for binding to the adenosine receptor (1991) (7)
- A benzylisoquinoline alkaloid from Doryphora sassafras. (2001) (7)
- Thiaplakortones A—D: Antimalarial Thiazine Alkaloids from the Australian Marine Sponge Plakortis lita (2014) (7)
- The Synthesis of Two Combinatorial Libraries Using a 4-(2-Thienyl)-pyrrole Template (2002) (6)
- Dragmacidol A and dragmacidolide A from the Australian marine sponge Dragmacidon australe (2015) (6)
- Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi (2021) (6)
- Amberlite XAD-7 as a Chromatographic Absorbent (1982) (6)
- Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation (2016) (6)
- Is it time for artificial intelligence to predict the function of natural products based on 2D-structure. (2019) (6)
- Unequivocal 13C NMR assignment of cyclohexadienyl rings in bromotyrosine‐derived metabolites from marine sponges (2012) (6)
- Chemical Investigation of Drug-Like Compounds from the Australian Tree, Neolitsea dealbata. (2011) (6)
- Antitumor activity and cardiac stimulatory effects of constituents of Anthopleura elegantissima. (1974) (6)
- The solution structures of calyculin A and dephosphonocalyculin A by NMR. (1999) (6)
- Synthesis of 5-Aminopyrazole-4-carbonitriles (1989) (6)
- 13C N.M.R. spin-lattice relaxation time measurements determining the major tautomer of 1-methylisoguanosine in solution (1980) (6)
- QPRI’s System for Screening of Natural Products (1999) (6)
- Diimidazo[1,2-c:4',5'-e]pyrimidines: N6-N1 conformationally restricted adenosines. (1998) (5)
- Grandisine A (I) and B (II), Novel Indolizidine Alkaloids with Human δ‐Opioid Receptor Binding Affinity from the Leaves of the Australian Rainforest Tree Elaeocarpus grandis. (2005) (5)
- 7′,8′-Dihydroobolactone, a Trypanocidal α-Pyrone from the Rainforest Tree Cryptocarya obovata. (2010) (5)
- Synthesis of a pyrimidine by elimination of nitrogen from a triazolo[4,5-d]pyrimidine (1990) (5)
- Structural Searching of Biosynthetic Enzymes to Predict Protein Targets of Natural Products (2017) (5)
- Traditional Chinese medicine extraction method by ethanol delivers drug-like molecules. (2019) (5)
- Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii (2014) (5)
- Identifying common metalloprotease inhibitors by protein fold types using Fourier transform mass spectrometry. (2007) (5)
- Building A Drug-Like Natural Product Library (2007) (5)
- Antiplasmodial activity of the natural product compounds alstonine and himbeline (2021) (5)
- Ligand identification of the adenosine A2A receptor in self-assembled nanodiscs by affinity mass spectrometry (2017) (5)
- Peculiarities of meroterpenoids and their bioproduction (2021) (5)
- N¹,N¹-Dimethyl-N³-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis. (2014) (4)
- The absolute stereochemistry and cytotoxicity of the ascidian-derived metabolite, longithorone J (2006) (4)
- Turning Metabolomics into Drug Discovery (2016) (4)
- Synthesis and Structure-Activity Relationship of Pyrazolo(3,4-d) pyrimidines: Potent and Selective Adenosine A1 Receptor Antagonists. (1997) (4)
- Anti-mycobacterial natural products and mechanisms of action. (2021) (4)
- Cardenolide glycosides from Elaeodendron australe var. integrifolium. (2014) (4)
- Marine Actinomycetes in Biodiscovery (2015) (4)
- Carbene induced rearrangement products from two furoquinolinone scaffolds (2010) (4)
- L-Azetidine-2-carboxylic acid, the antidermatophyte constituent of two marine sponges (1978) (4)
- Antimicrobial Benzyltetrahydroisoquinoline-Derived Alkaloids from the Leaves of Doryphora aromatica (2021) (4)
- Calcium channels and iron metabolism: A redox catastrophe in Parkinson's disease and an innovative path to novel therapies? (2021) (4)
- Linckosides enhance proliferation and induce morphological changes in human olfactory ensheathing cells (2016) (4)
- Unique Polybrominated Hydrocarbons from the Australian Endemic Red Alga Ptilonia australasica. (2016) (3)
- Bioinspiration from Marine Scaffolds (2018) (3)
- Dictamins A–C, three unprecedented apotirucallane-type trinortriterpenoids from Dictamnus dasycarpus (2013) (3)
- Comparing atom-based with residue-based descriptors in predicting binding site similarity: do backbone atoms matter? (2016) (3)
- Antitrypanosomal Pyridoacridine Alkaloids from the Australian Ascidian Polysyncraton echinatum. (2010) (3)
- Developing a drug-like natural product library (Journal of Natural Products (2008) 71, (468)) (2008) (3)
- Styracifoline from the Vietnamese Plant Desmodium styracifolium: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins (2021) (3)
- Bioaffinity Mass Spectrometry Screening using Droplet-Based Microfluidics (2015) (3)
- 5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae). (2017) (3)
- au Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes , Actinokineospora sp . EG 49 and Nocardiopsis sp . RV 163 (2017) (3)
- Progress toward establishing an open access molecular screening capability in the Australasian region. (2007) (3)
- 4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog (1991) (3)
- Zwitterionic 2-(methylamino)ethanesulfonic acid (2003) (3)
- A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants Gloriosa superba and Alangium villosum against Parkinson's Disease. (2020) (3)
- 3-Hydroxy-4-methoxyphenethylamine, the cardioactive constituent of a soft coral (1981) (3)
- Recent Developments in Natural Products: Potential Impact on Antibacterial Drug Discovery (2011) (3)
- Collision-Induced Affinity Selection Mass Spectrometry for Identification of Ligands (2022) (3)
- Naturally occurring scaffolds for compound library design: convenient access to bis-aryl 1-azaadamantanes carrying a vicinal amino alcohol motif (2014) (2)
- Antineoplastic agents. XXVIII. Camptothecin .delta.-lactone (1972) (2)
- Study of the Novel Non-xanthine Heterocyclic Compound GU285 as a Potent Non-selective Adenosine Receptor Antagonist in the Rat (2002) (2)
- Pyrazolo(3,4‐d)pyrimidines; Adenosine Receptor Selectivity. (1996) (2)
- An explanation of the substituent effect of 1,3,8-trisubstituted xanthines on adenosine A1/A2 affinity. (1992) (2)
- Pseudoceratinazole A: A Novel Bromotyrosine Alkaloid from the Australian Sponge Pseudoceratina sp. (2010) (2)
- Basics and principles for building natural product–based libraries for HTS (2012) (2)
- Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase (2019) (2)
- The Evolution of Compound Libraries for Applied and Basic Research (2007) (2)
- Natural product-based PROteolysis TArgeting Chimeras (PROTACs). (2022) (2)
- Advantages of Molecular Weight Identification during Native MS Screening (2018) (2)
- Biodiscovery for Natural Product Pharmaceuticals: An Australian Experience (2007) (2)
- Meeting the Challenge 2: Identification of Potential Chemical Probes for Parkinson's Disease from Ligusticum chuanxiong Hort Using Cytological Profiling. (2022) (1)
- Metabolite-protein interactions: Native mass spectrometry and collision induced affinity selection mass spectrometry in natural product screening (2022) (1)
- P-46 FLABELLAZOLES A AND B, NOVEL IMIDAZO-PYRANO-IMIDAZOLE ALKALOIDS FROM THE AUSTRALIAN MARINE SPONGE STYLISSA FLABELLATA, ANTAGONISTS OF THE P2X_7 RECEPTOR (2006) (1)
- Axinellamines A—D, Novel Imidazo—Azolo—Imidazole Alkaloids from the Australian Marine Sponge Axinella sp. (1999) (1)
- Quaternized Acridine Maleimide MALDI Probe Enables Mass Spectrometry Imaging of Thiols. (2022) (1)
- Graphical Abstract Chemical investigation of an antimalarial Chinese medicinal herb Picrorhiza scrophulariiflora (2014) (1)
- A note of caution in the use of receptor binding assays to screen marine organisms: the action of halistanol trisulphate on adenosine receptors. (1992) (1)
- Diimidazo[1,2-c:4',5'-e]pyrimidines: adenosine agonist activity demonstrated by microphysiometry. (1998) (1)
- N 1 , N 1 -dimethyl- N 3 -(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis (2015) (1)
- Botryllamides K and L, New Tyrosine Derivatives from the Australian Ascidian Aplidium altarium. (2010) (1)
- Isolate from the annelid, Reteterebella queenslandia (Australia), active against Ehrlich ascites tumor. (1973) (1)
- Exiguaquinol: A Novel Pentacyclic Hydroquinone from Neopetrosia exigua that Inhibits Helicobacter pylori Murl. (2008) (1)
- Anti-staphylococcal properties of propolis from Australian stingless bees Tetragonula carbonaria (2014) (1)
- Logistic Considerations to Deliver Natural Product Libraries for High-Throughput Screening... (2016) (1)
- The occurrence of 5-hydroxytryptamine in the holothurian,Pentacter crassa (1981) (1)
- Identifying New Ligands for JNK3 by Fluorescence Thermal Shift Assays and Native Mass Spectrometry (2022) (1)
- Kororamide B, a Brominated Alkaloid from the Bryozoan Amathia tortuosa and Its Effects on Parkinson′s Disease Cells (2015) (1)
- Revised Structure of Palau′amine. (2007) (1)
- In silico Driven Pharmacognosy: Forth, Back and Reverse (2015) (1)
- P-102 ISOLATION OF A NEW XANTHONE FROM GARCINIA MANGOSTANA (2006) (0)
- Pyrazolo(3,4‐d)pyrimidine Analogues of Isoguanine. (1992) (0)
- SYNTHESIS OF STEREOISOMERIC PINANTHROMBOXANE DERIVATIVES AND EVALUATION OF THE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS (1983) (0)
- Heterogeneous nuclear ribonucleoprotein A2B1, a novel drug target for hepatitis B virus infection (2021) (0)
- Investigating the Use of AlphaScreen in the High Throughput Screening of Natural Product Extracts (2007) (0)
- Bioactives v bioproducts. The road from discovery to market. (2008) (0)
- High-pressure synthesis of enantiomerically pure C-6 substituted pyrazol. (2001) (0)
- 924 The Ascidian Natural Product Eusynstyelamide B Induces G2/M Phase Arrest in Human Breast Cancer Cells (2012) (0)
- Spermatinamine, the First Natural Product Inhibitor of Isoprenylcysteine Carboxyl Methyltransferase, a New Cancer Target (2008) (0)
- Antimalarial natural products from Picrorhiza scrophulariiflora (2012) (0)
- Repairing the olfactory nerve: potent stimulation of olfactory ensheathing cell activity by the natural compound curcumin (2015) (0)
- Tropane Alkaloids from Darlingia darlingiana. (2000) (0)
- Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity (2016) (0)
- Diimidazo[1,2-c:4′,5′-e]pyrimidines: N6—N1 Conformationally Restricted Adenosines. (1998) (0)
- Isolation of natural product antimalarial compounds from tropical Queensland and Papua New Guinean plants (2008) (0)
- Synthesis of Natural Products Isolated from Marine Organisms: Potential Inhibitors of IGF-1 and IGF Binding Protein Interaction (2008) (0)
- The Discovery of Novel Marine Organism Derived Leads to Treat Osteoarthritis (2007) (0)
- A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicron in vivo (2022) (0)
- Drug-Repurposing Screening Identifies a Gallic Acid Binding Site on SARS-CoV-2 Non-structural Protein 7. (2023) (0)
- Systemic chemical proteomics based target identification and validation of OMe‐Syn, a new anti‐angiogenic natural small molecule (2012) (0)
- Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134 (2019) (0)
- Assessment of habitat function - A case study in estuarine fish habitat creation (2003) (0)
- Identification of Natural Product Drugs for TGFBIp-associated Corneal Dystrophies (2017) (0)
- Correction to Total synthesis of clavatadine A. (2015) (0)
- Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins (2013) (0)
- Potassium Channels in Parkinson's Disease: Potential Roles in its Pathogenesis and Innovative Molecular Targets for Treatment. (2023) (0)
- 4-Amino-1-phenylpyrazolo(3,4-d)pyrimidin-6(5H)-one, an Isoguanosine Analogue. (1991) (0)
- Radioligand binding and cardiovascular effects of a new adenosine antagonist (1992) (0)
- Dictamins A—C [(Ia), (Ib), (II)], Three Unprecedented Apotirucallane-Type Trinortriterpenoids from Dictamnus dasycarpus. (2013) (0)
- Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation (2016) (0)
- Flinderoles A—C: Antimalarial Bis-indole Alkaloids from Flindersia Species. (2009) (0)
- Two Novel Vanilic Acid Derivatives from the Green Algae Chlorophyta cladophora socialis (2007) (0)
- Establishing an Open Access CM Facility in Australia (2007) (0)
- Type I methemoglobinemia arising due to a change in cofactor specificity of cytochrome B5 reductase (2005) (0)
- 4-Amino-2,6-dichloro-5-nitropyrimidine (2004) (0)
- Visualization tool for simulating ligand-receptor binding process (1996) (0)
- Synthesis of 2‐Substituted Pyrazolo(3,4‐d)pyrimidines. (1992) (0)
- Synthesis of two chiral octahydroindole scaffolds for drug discovery (2016) (0)
- Eudistomin V, a new beta-carboline from the Australian ascidian Pseudodistoma aureum. (1998) (0)
- Dragmacidol A and Dragmacidolide A from the Australian Marine Sponge Dragmacidon australe. (2015) (0)
- Synthesis and SAR Results of the Natural Product Compounds Isolated from Marine Organisms: Potential Inhibitors of IGF – IGFBP-n Interaction (2007) (0)
- Bioassay-guided fractionation of cytotoxic ascidian-derived compounds using the xCELLigence Syste (2011) (0)
- Erratum: 13C N.M.R. spin-lattice relaxation time measurements determining the major tautomer of 1-methylisoguanosine in solution (Journal of the Chemical Society, Chemical Communications (1980) (340)) (1980) (0)
- The effect of Epac activation on human coronary artery endothelial cells (2014) (0)
- Synthesis and Adenosine Receptor Affinity of a Series of Pyrazolo(3,4- d)pyrimidine Analogues of 1-Methylisoguanosine. (1992) (0)
- The camptothecin -lectone. (1972) (0)
- A novel class of antiparasitic indole alkaloids from Flindersia species. (2008) (0)
- Identification of a novel Th1 promoting vaccine adjuvant from natural products (P4451) (2013) (0)
- Antimalarial natural products from traditional chinese medicinal herbs (2012) (0)
- Explore novel JNK3 ligand by HTS of designed scaffold library using FTS assay (2017) (0)
- Solving the supply of Resveratrol Tetramers from Papua New Guinean rainforest Anisoptera species (Dipterocarpaceae) that inhibit bacterial type III secretion systems (2014) (0)
- Listening to nature's hints : exploiting a natural product scaffold to simplify a complex chemical structure (2013) (0)
- Prunolides A, B, and C: Novel Tetraphenolic Bis‐Spiroketals from the Australian Ascidian Synoicum prunum. (1999) (0)
- Similar Interactions of Natural Products with Biosynthetic Enyzmes and Therapeutic Targets Could Explain Why Nature Produces such as Large Proportion of Existing Drugs (2011) (0)
- High-Pressure Synthesis of Enantiomerically Pure C-6 Substituted Pyrazolo[3,4-d]pyrimidines. (2001) (0)
- Application of native mass spectrometry in early stage drug discovery for the identification of novel TGFBIp-ligand interactions. (2018) (0)
- Structure Determination of Pentacyclic Pyridoacridine Alkaloids from the Australian Marine Organisms Ancorina geodides and Cnemidocarpa Stolonifera. (2015) (0)
- Epac activation in cultured human coronary artery endothelial cells (HCAECs) triggers vascular endothelial cadherin (VE-cadherin) and connexin 37 (Cx37) re-distribution and facilitates intercellular communication (2014) (0)
- Curcumin Increases Proliferation and Enhances Migration of Olfactory Ensheathing Cells (2013) (0)
- Screening Nature: Natural Products Challenge Scientific Rules and Increase Screening Hit Rates (2006) (0)
- 4-Amino-2-chloro-5-nitro-6-(propylamino)pyrimidine (2004) (0)
- New beta and gammalumicolchicosides from Gloriosa sp. (2014) (0)
- Establishing a Publicly Accessible Compound Repository to Stimulate Drug Discovery in Australia (2007) (0)
- Browsing Biodiversity: HTS and Natural Product Libraries (1999) (0)
- Synthesis of a Pyrimidine by Elimination of Nitrogen from a Triazolo-( 4,5-d)pyrimidine. (1991) (0)
- Metabolomic strategies in dereplication for targeted cultivation and isolation of new bioactive secondary metabolites from fungal endophytes and marine microbial symbionts (2013) (0)
- Carbene Induced Rearrangement Products from Two Furoquinolinone Scaffolds. (2011) (0)
- Lysianadioic Acid (I), a Carboxypeptidase B Inhibitor from Lysiana subfalcata. (2008) (0)
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What Schools Are Affiliated With Ronald J. Quinn?
Ronald J. Quinn is affiliated with the following schools:
