Ronald M. Bukowski
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Philosophy
Ronald M. Bukowski's Degrees
- Doctorate Medicine Harvard University
- PhD Biomedical Sciences Stanford University
Why Is Ronald M. Bukowski Influential?
(Suggest an Edit or Addition)Ronald M. Bukowski's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sorafenib in advanced clear-cell renal-cell carcinoma. (2007) (4691)
- Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. (2007) (4385)
- Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma (2009) (2096)
- Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. (2009) (1682)
- Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. (2009) (1081)
- Sunitinib in patients with metastatic renal cell carcinoma. (2006) (965)
- Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients (2009) (832)
- Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group. (1997) (697)
- Sunitinib Reverses Type-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients (2008) (479)
- Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinoma. (2009) (462)
- Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study. (2007) (433)
- Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials (2004) (399)
- Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. (2008) (395)
- Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma. (2013) (394)
- Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. (2007) (378)
- The Modulation of Fluorouracil With Leucovorin in Metastatic Colorectal Carcinoma A Prospective Randomized Phase III Trial (1990) (363)
- Randomized phase III trial of the Raf kinase and VEGFR inhibitor sorafenib (BAY 43–9006) in patients with advanced renal cell carcinoma (RCC) (2005) (359)
- Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. (2007) (315)
- Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. (2008) (313)
- The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor. (1998) (305)
- A Phase I Study with Neratinib (HKI-272), an Irreversible Pan ErbB Receptor Tyrosine Kinase Inhibitor, in Patients with Solid Tumors (2009) (276)
- Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4+ T Cell Responses Against MAGE-6 in HLA-DRB1*0401+ Patients With Renal Cell Carcinoma or Melanoma (2002) (272)
- Natural history and therapy of metastatic renal cell carcinoma (1997) (256)
- Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America (2010) (249)
- Plasmapheresis in the treatment of thrombotic thrombocytopenic purpura. (1977) (248)
- Clinical factors associated with outcome in patients with metastatic clear‐cell renal cell carcinoma treated with vascular endothelial growth factor‐targeted therapy (2007) (225)
- Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody. (2004) (224)
- Phase I trial of subcutaneous recombinant human interleukin-12 in patients with advanced renal cell carcinoma. (1998) (215)
- Multicenter, randomized, phase III trial of CD8(+) tumor-infiltrating lymphocytes in combination with recombinant interleukin-2 in metastatic renal cell carcinoma. (1999) (210)
- Estrogen receptor mutations in tamoxifen-resistant breast cancer. (1994) (201)
- Sunitinib efficacy against advanced renal cell carcinoma. (2007) (201)
- Recombinant human erythropoietin therapy for anemic cancer patients on combination chemotherapy. (1993) (199)
- Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma (2008) (195)
- Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC) (2008) (187)
- F-18 fluorodeoxyglucose positron emission tomography in the evaluation of distant metastases from renal cell carcinoma. (2003) (184)
- Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12. (1996) (183)
- T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. (1993) (177)
- Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. (2009) (175)
- Can we predict long-term survival after pulmonary metastasectomy for renal cell carcinoma? (2005) (169)
- Biomarkers Predicting Outcome in Patients with Advanced Renal Cell Carcinoma: Results from Sorafenib Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial (2010) (168)
- AG-013736, a multi-target tyrosine kinase receptor inhibitor, demonstrates anti-tumor activity in a Phase 2 study of cytokine-refractory, metastatic renal cell cancer (RCC) (2005) (163)
- Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma (2015) (160)
- von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. (2008) (159)
- Mechanisms of apoptosis in T cells from patients with renal cell carcinoma. (1999) (158)
- Disease stage variation in CD4+ and CD8+ T-cell reactivity to the receptor tyrosine kinase EphA2 in patients with renal cell carcinoma. (2003) (150)
- Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. (2008) (145)
- Final results of the randomized phase III trial of sorafenib in advanced renal cell carcinoma: Survival and biomarker analysis (2007) (144)
- Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy. (2008) (144)
- Sorafenib for Older Patients With Renal Cell Carcinoma: Subset Analysis From a Randomized Trial (2008) (138)
- Randomized phase II trial of first-line treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: Final results (2007) (137)
- Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-{alpha}) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC) (2006) (135)
- Exchange transfusions in the treatment of thrombotic thrombocytopenic purpura. (1976) (133)
- Prognostic factors for survival in 1059 patients treated with sunitinib for metastatic renal cell carcinoma (2013) (130)
- Clinical modulation of doxorubicin resistance by the calmodulin-inhibitor, trifluoperazine: a phase I/II trial. (1988) (127)
- Phase 2 trials of SU11248 show antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma (RCC) (2005) (124)
- Pegylated interferon alfa-2b treatment for patients with solid tumors: a phase I/II study. (2002) (122)
- Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells. (1999) (122)
- Treating cancer with PEG Intron (2002) (119)
- The impact of adjuvant nephrectomy on multimodality treatment of metastatic renal cell carcinoma. (1994) (115)
- Phase I/II Study of Vaccination With Electrofused Allogeneic Dendritic Cells/Autologous Tumor-derived Cells in Patients With Stage IV Renal Cell Carcinoma (2007) (114)
- Randomized multicenter phase II trial of subcutaneous recombinant human interleukin-12 versus interferon-alpha 2a for patients with advanced renal cell carcinoma. (2001) (110)
- Inhibition of NF-κB Activity in Human T Lymphocytes Induces Caspase-Dependent Apoptosis Without Detectable Activation of Caspase-1 and -3 (1999) (109)
- Targeted therapy for metastatic renal cell carcinoma. (2006) (109)
- Cytokine therapy for metastatic renal cell carcinoma. (2001) (109)
- Clinical results and characterization of tumor-infiltrating lymphocytes with or without recombinant interleukin 2 in human metastatic renal cell carcinoma. (1991) (106)
- Characterization of a human renal cell carcinoma specific cytotoxic CD8+ T cell line. (1992) (106)
- Selective cytokine gene expression in renal cell carcinoma tumor cells and tumor‐infiltrating lymphocytes (1995) (105)
- Skeletal Complications in Patients with Bone Metastases from Renal Cell Carcinoma and Therapeutic Benefits of Zoledronic Acid (2004) (104)
- Characterization of the cytolytic activity of CD4+ and CD8+ tumor-infiltrating lymphocytes in human renal cell carcinoma. (1990) (102)
- Phase II trial of mitotane and cisplatin in patients with adrenal carcinoma: a Southwest Oncology Group study. (1993) (100)
- Development and validation of the Functional Assessment of Cancer Therapy-Kidney Symptom Index (FKSI). (2006) (99)
- Expression of EphA2 is prognostic of disease-free interval and overall survival in surgically treated patients with renal cell carcinoma. (2005) (98)
- Phase II trial of high-dose intermittent interleukin-2 in metastatic renal cell carcinoma: a Southwest Oncology Group study. (1990) (96)
- Dead or dying: necrosis versus apoptosis in caspase-deficient human renal cell carcinoma. (1999) (95)
- Thrombocytosis as a prognostic factor for survival in patients with metastatic renal cell carcinoma (2005) (95)
- Successful combination chemotherapy for metastatic parathyroid carcinoma. (1984) (95)
- Therapy of thrombotic thrombocytopenic purpura: an overview. (1981) (94)
- Effects of Sorafenib on Symptoms and Quality of Life: Results From a Large Randomized Placebo-Controlled Study in Renal Cancer (2007) (93)
- Sunitinib versus interferon-alfa (IFN-α) as first-line treatment of metastatic renal cell carcinoma (mRCC): Updated results and analysis of prognostic factors (2007) (92)
- Tumor-induced suppression of T lymphocyte proliferation coincides with inhibition of Jak3 expression and IL-2 receptor signaling: role of soluble products from human renal cell carcinomas. (1997) (90)
- T cells from renal cell carcinoma patients exhibit an abnormal pattern of kappa B-specific DNA-binding activity: a preliminary report. (1994) (90)
- The management of recurrent ovarian cancer. (2007) (88)
- A phase II trial of combination chemotherapy in patients with metastatic carcinoid tumors. A southwest oncology group study (1987) (88)
- Phase II trial of dimethyltriazenoimidazole carboxamide in patients with metastatic carcinoid (1994) (88)
- Therapy and outcome of small cell carcinoma of the kidney (2003) (87)
- A Phase I Study of Sunitinib plus Bevacizumab in Advanced Solid Tumors (2009) (87)
- The role of inflammation in kidney cancer. (2014) (87)
- Alterations in NFκB Activation in T Lymphocytes of Patients With Renal Cell Carcinoma (1999) (87)
- Development and validation of a scale to measure disease-related symptoms of kidney cancer. (2007) (86)
- GM2 expression in renal cell carcinoma: potential role in tumor-induced T-cell dysfunction. (2006) (85)
- T cells infiltrating non-Hodgkin's B cell lymphomas show altered tyrosine phosphorylation pattern even though T cell receptor/CD3-associated kinases are present. (1995) (83)
- Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC). (2006) (83)
- Novel erythropoiesis stimulating protein (NESP) for the treatment of anaemia of chronic disease associated with cancer (2001) (82)
- Bevacizumab with or without erlotinib in metastatic renal cell carcinoma (RCC). (2006) (82)
- Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy. (1998) (81)
- Phase 1 trial of Anvirzel™ in patients with refractory solid tumors (2006) (80)
- Phase I/II trial of all-trans retinoic acid and tamoxifen in patients with advanced breast cancer. (1998) (80)
- Gangliosides expressed by the renal cell carcinoma cell line SK-RC-45 are involved in tumor-induced apoptosis of T cells. (2003) (80)
- Caspase-dependent and -independent death pathways in cancer therapy (2000) (80)
- Characterization of tumor-infiltrating lymphocyte subsets from human renal cell carcinoma: specific reactivity defined by cytotoxicity, interferon-gamma secretion, and proliferation. (1994) (79)
- A Phase II trial of pegylated liposomal doxorubicin, vincristine, and reduced‐dose dexamethasone combination therapy in newly diagnosed multiple myeloma patients (2002) (78)
- 5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer: a randomized comparison. A Southwest Oncology Group Study. (1987) (78)
- Effect of Renal Cell Carcinomas on the Development of Type 1 T-Cell Responses (2004) (78)
- A multicenter prospective trial of sorafenib in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab (2008) (77)
- Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. (1999) (76)
- Clinical and immunologic effects of subcutaneously administered interleukin-12 and interferon alfa-2b: phase I trial of patients with metastatic renal cell carcinoma or malignant melanoma. (2004) (74)
- Prognostic Factors in Patients with Advanced Renal Cell Carcinoma (2004) (73)
- Patients With Renal Cell Carcinoma or Melanoma (2002) (72)
- Randomized trial of 5‐fluorouracil and mitomycin C with or without streptozotocin for advanced pancreatic cancer. A Southwest oncology group study (1983) (72)
- Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma (2014) (71)
- MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma. (2003) (70)
- Sunitinib in metastatic renal cell carcinoma (mRCC): Preliminary assessment of toxicity in an expanded access trial with subpopulation analysis (2007) (68)
- Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab (2010) (67)
- Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of renal cell carcinoma (2016) (66)
- A population‐based study evaluating the impact of sunitinib on overall survival in the treatment of patients with metastatic renal cell cancer (2009) (66)
- Results of whole brain radiotherapy and recursive partitioning analysis in patients with brain metastases from renal cell carcinoma: a retrospective study. (2004) (65)
- Myeloid-derived suppressor cells: A novel therapeutic target (2009) (63)
- Interleukin-2 in Cancer Therapy (2000) (62)
- Phase I Clinical Trial of Interleukin 2 and α-Interferon: Toxicity and Immunologic Effects (1989) (62)
- A randomized, double-blind trial of fluorouracil plus placebo versus fluorouracil plus oral leucovorin in patients with metastatic colorectal cancer. (1993) (61)
- HKI-272, an irreversible pan erbB receptor tyrosine kinase inhibitor: Preliminary phase 1 results in patients with solid tumors. (2006) (61)
- Impaired Activation of NFκB in T Cells From a Subset of Renal Cell Carcinoma Patients Is Mediated by Inhibition of Phosphorylation and Degradation of the Inhibitor, IκB (1998) (61)
- Treatment of limited small-cell lung cancer with etoposide and cisplatin alternating with vincristine, doxorubicin, and cyclophosphamide versus concurrent etoposide, vincristine, doxorubicin, and cyclophosphamide and chest radiotherapy: a Southwest Oncology Group Study. (1990) (60)
- Exposure-response of sunitinib in metastatic renal cell carcinoma (mRCC): A population pharmacokinetic/pharmacodynamic (PKPD) approach (2007) (60)
- Efficacy and safety of sunitinib malate (SU11248) in bevacizumab-refractory metastatic renal cell carcinoma (mRCC). (2006) (60)
- Phosphorylation of Serine 1106 in the Catalytic Domain of Topoisomerase IIα Regulates Enzymatic Activity and Drug Sensitivity* (2003) (60)
- Prognostic factors of metastatic renal cell carcinoma after failure of immunotherapy: new paradigm from a large phase III trial with shark cartilage extract AE 941. (2007) (59)
- Treatment of patients with metastatic renal cell cancer (2006) (59)
- Combination radiation and chemotherapy for the treatment of squamous cell carcinoma of the male and female urethra. (1995) (58)
- Randomized phase II trial of the multi-kinase inhibitor sorafenib versus interferon (IFN) in treatment-naïve patients with metastatic renal cell carcinoma (mRCC). (2006) (57)
- Alternating combination chemotherapy in patients with extragonadal germ cell tumors a southwest oncology group study (1993) (57)
- The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: Safety and efficacy (2007) (56)
- A phase II study of the dual MET/VEGFR2 inhibitor XL880 in patients (pts) with papillary renal carcinoma (PRC) (2007) (55)
- Gallium nitrate in advanced bladder carcinoma: Southwest Oncology Group study. (1991) (55)
- Sequential use of targeted agents in the treatment of renal cell carcinoma. (2011) (54)
- Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma (2005) (54)
- Hepatic artery infusion of 5‐fluorouracil and mitomycin C in cholangiocarcinoma and gallbladder carcinoma (1984) (54)
- Prognostic factors associated with long-term survival in previously untreated metastatic renal cell carcinoma. (2006) (54)
- Phase II study of lenalidomide in patients with metastatic renal cell carcinoma (2006) (54)
- Degradation of NF-κB in T Cells by Gangliosides Expressed on Renal Cell Carcinomas1 (2004) (54)
- Gastric epithelial atypia associated with hepatic arterial infusion chemotherapy. Its distinction from early gastric carcinoma (1985) (53)
- Magnetic resonance with marked T2-weighted images: improved demonstration of brain lesions, tumor, and edema. (1985) (53)
- Tumor-induced sensitivity to apoptosis in T cells from patients with renal cell carcinoma: role of nuclear factor-kappaB suppression. (2001) (52)
- Mechanism of apoptosis induced by zinc deficiency in peripheral blood T lymphocytes (2001) (52)
- Mechanisms of immune evasion by renal cell carcinoma: tumor-induced T-lymphocyte apoptosis and NFkappaB suppression. (2002) (51)
- Randomized trial of carboplatin plus amifostine versus carboplatin alone in patients with advanced solid tumors (1997) (50)
- Cytokine combinations: therapeutic use in patients with advanced renal cell carcinoma. (2000) (49)
- Novel vascular targeting/disrupting agents: Combretastatin A4 phosphate and related compounds (2005) (49)
- Efficacy of multimodality therapy in advanced renal cell carcinoma. (1998) (48)
- Prognostic factors for survival in metastatic renal cell carcinoma (2009) (47)
- The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial: Safety and efficacy in patients (pts) with non-clear cell (NCC) renal cell carcinoma (RCC) (2007) (47)
- T-cell adoptive immunotherapy of metastatic renal cell carcinoma. (1999) (46)
- Randomized phase III trial of sorafenib in advanced renal cell carcinoma (RCC): Impact of crossover on survival. (2007) (46)
- Interferon-γ and CXC Chemokine Induction by Interleukin 12 in Renal Cell Carcinoma (1999) (45)
- A Phase I Pharmacokinetic and Pharmacodynamic Study of S-3304, a Novel Matrix Metalloproteinase Inhibitor, in Patients with Advanced and Refractory Solid Tumors (2007) (45)
- Roles of NF-κB and 26 S Proteasome in Apoptotic Cell Death Induced by Topoisomerase I and II Poisons in Human Nonsmall Cell Lung Carcinoma* (2001) (45)
- Randomized phase III trial of sorafenib in advanced renal cell carcinoma (RCC): Impact of crossover on survival (2006) (44)
- Safety and efficacy of PF-3512676 for the treatment of stage IV renal cell carcinoma: an open-label, multicenter phase I/II study. (2009) (44)
- Phase II trial of sunitinib in bevacizumab-refractory metastatic renal cell carcinoma (mRCC): Updated results and analysis of circulating biomarkers (2007) (44)
- The treatment of thrombotic thrombocytopenic purpura with exchange transfusions, plasma infusions, and plasma exchange. (1987) (44)
- Safety and Efficacy of Sorafenib in Elderly Patients Treated in the North American Advanced Renal Cell Carcinoma Sorafenib Expanded Access Program (2010) (43)
- Phase II study of the efficacy and safety of oral GD0039 in patients with locally advanced or metastatic renal cell carcinoma (2005) (43)
- Chemokine gene expression in the murine renal cell carcinoma, RENCA, following treatment in vivo with interferon-alpha and interleukin-2. (1994) (43)
- Simultaneous treatment with cisplatin and radiation therapy for advanced solid tumors: a pilot study. (1981) (43)
- PROSTACYCLIN THERAPY OF THROMBOTIC THROMBOCYTOPENIC PURPURA (1980) (42)
- Phase I trial of high-dose bolus interleukin-2 and interferon alfa-2a in patients with metastatic malignancy. (1992) (42)
- Phase I study of flavopiridol in combination with Paclitaxel and Carboplatin in patients with non-small-cell lung cancer. (2008) (42)
- Evaluation of combination chemotherapy and phase II agents in pancreatic adenocarcinoma. A southwest oncology group study (1993) (42)
- Phase II trial of chlorozotocin and fluorouracil in islet cell carcinoma: a Southwest Oncology Group study. (1992) (42)
- Tumor-induced dysfunction in interleukin-2 production and interleukin-2 receptor signaling: a mechanism of immune escape. (2000) (42)
- Sunitinib therapy for patients (pts) with metastatic renal cell carcinoma (mRCC): Updated results of two phase II trials and prognostic factor analysis for survival (2007) (41)
- Til from renal‐cell carcinoma: Restimulation with tumor influences proliferation and cytolytic activity (1990) (41)
- Recent advances in systemic therapy for gastrointestinal neuroendocrine tumors. (1999) (41)
- Phase I trial of phenoxodiol delivered by continuous intravenous infusion in patients with solid cancer. (2006) (40)
- Phase II Trial of Liposomal Doxorubicin (Doxil®) in Advanced Soft Tissue Sarcomas (2000) (40)
- Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. (1999) (40)
- Sunitinib‐induced macrocytosis in patients with metastatic renal cell carcinoma (2008) (39)
- Anti-angiogenic targets in the treatment of advanced renal cell carcinoma. (2008) (39)
- Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma (2008) (39)
- Phase II trial of interleukin-2 and interferon-alpha in patients with renal cell carcinoma: clinical results and immunologic correlates of response. (1997) (39)
- The current role of angiogenesis inhibitors in the treatment of renal cell carcinoma. (2006) (39)
- Casein kinase I δ/ɛ phosphorylates topoisomerase IIα at serine-1106 and modulates DNA cleavage activity (2008) (38)
- Immunotherapy of disseminated renal cell carcinoma with transfer factor. (1977) (38)
- Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells. (1996) (38)
- Sensitization of DNA damage–induced apoptosis by the proteasome inhibitor PS-341 is p53 dependent and involves target proteins 14-3-3σ and survivin (2005) (37)
- Clinical practice guidelines: renal cell carcinoma. (1997) (37)
- Renal Cell Carcinoma Tumors Induce T Cell Apoptosis through Receptor-Dependent and Receptor-Independent Pathways1 (2008) (37)
- Combination chemotherapy for islet cell carcinoma and metastatic carcinoid tumors with 5-fluorouracil and streptozotocin. (1979) (36)
- Phase II trial of dimethyltriazenoimidazole carboxamide in patients with metastatic carcinoid. A Southwest Oncology Group study. (1994) (35)
- Phase I trial of subcutaneous recombinant macrophage colony-stimulating factor: clinical and immunomodulatory effects. (1994) (35)
- Third Generation Tyrosine Kinase Inhibitors and Their Development in Advanced Renal Cell Carcinoma (2012) (35)
- Retroperitoneal malignancies several years after initial treatment of germ cell cancer of the testis (1984) (34)
- A Phase I–II trial of polyethylene glycol‐conjugated L‐asparaginase in patients with multiple myeloma (2003) (34)
- Phase I trial of dipyridamole with 5-fluorouracil and folinic acid. (1990) (34)
- Intra-arterial chemotherapy as an adjuvant to surgery in transitional cell carcinoma of the bladder. (1986) (33)
- The prognostic significance of epidermal growth factor receptor expression in clear-cell renal cell carcinoma: a call for standardized methods for immunohistochemical evaluation. (2007) (33)
- Temsirolimus: a safety and efficacy review (2012) (33)
- GM1 and tumor necrosis factor-alpha, overexpressed in renal cell carcinoma, synergize to induce T-cell apoptosis. (2008) (33)
- Rapid analysis of docetaxel in human plasma by tandem mass spectrometry with on-line sample extraction. (2004) (32)
- Inhibition of proteasome activity by bortezomib in renal cancer cells is p53 dependent and VHL independent. (2009) (32)
- Erythropoietin production. A potential marker for interleukin‐2/interferon‐responsive tumors (1993) (32)
- Phase II trial of streptozotocin, mitomycin C, and 5-fluorouracil in adenocarcinoma of the pancreas. (1980) (32)
- The promise of targeted therapy: cancer drugs become more specific. (2004) (32)
- Pazopanib: a multikinase inhibitor with activity in advanced renal cell carcinoma (2010) (32)
- Amifostine (Ethyol): dosing, administration and patient management guidelines. (1996) (31)
- Pseudo-gamma heavy chain (IgG4 lambda) deposition disease. (1992) (31)
- The need for cytoprotection. (1996) (31)
- AE-941, a multifunctional antiangiogenic compound: trials in renal cell carcinoma (2003) (31)
- Pharmacokinetics and bioequivalence of etoposide following intravenous administration of etoposide phosphate and etoposide in patients with solid tumors. (1995) (31)
- Nephron sparing surgery in patients with metastatic renal cell carcinoma. (1996) (31)
- Downregulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest (2006) (31)
- Prolonged complete responses and near-complete responses to sunitinib in metastatic renal cell carcinoma. (2007) (31)
- Phase II study of volociximab (M200), an α5β1 anti-integrin antibody in refractory metastatic clear cell renal cell cancer (RCC). (2006) (31)
- Renal cell carcinoma : molecular biology, immunology, and clinical management (2000) (30)
- Combination chemotherapy of metastatic thyroid cancer. Phase II study. (1983) (30)
- Telomerase activity in Stage II colorectal carcinoma (2002) (30)
- Phase II trial of 5‐fluorouracil, adriamycin, mitomycin C, and streptozotocin (FAM‐S) in pancreatic carcinoma (1982) (29)
- T cell lymphoma occurring in Sjögren's syndrome. (1984) (29)
- Phase II trial of subcutaneously administered granulocyte‐macrophage colony‐stimulating factor in patients with metastatic renal cell carcinoma (1996) (29)
- RANDOMISED PHASE III TRIAL OF THE MULTIKINASE INHIBITOR SORAFENIB (BAY 43-9006) IN PATIENTS WITH ADVANCED RENAL CELL CARCINOMA (RCC) (2006) (29)
- Antitumor effects of sorafenib and sunitinib in patients (pts) with metastatic renal cell carcinoma (mRCC) who had prior therapy with anti-angiogenic agents. (2006) (28)
- Recent advances in diagnosis and therapy of neuroendocrine tumors of the gastrointestinal tract. (1997) (28)
- Efficacy and safety of sorafenib in patients with advanced renal cell carcinoma with and without prior cytokine therapy, a subanalysis of TARGET (2010) (28)
- Innovations and Challenges in Renal Cancer (2004) (28)
- Phase I trial of continuous infusion recombinant interleukin-2 and intermittent recombinant interferon-alpha 2a: clinical effects. (1990) (28)
- Immunotherapy of Renal Cell Carcinoma (1999) (27)
- Final results from phase II study of volociximab, an α5β1 anti-integrin antibody, in refractory or relapsed metastatic clear cell renal cell carcinoma (mCCRCC) (2007) (27)
- Enhancement in Specific CD8+ T Cell Recognition of EphA2+ Tumors In Vitro and In Vivo after Treatment with Ligand Agonists1 (2008) (27)
- Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors (2007) (26)
- Prognostic factors affecting remission, remission duration, and survival in adult acute nonlymphocytic leukemia (1979) (26)
- Defective granzyme B gene expression and lytic response in T lymphocytes infiltrating human renal cell carcinoma. (1997) (26)
- Everolimus in the treatment of renal cell carcinoma and neuroendocrine tumors (2010) (26)
- Guidelines for the definition of time-to-event end points in renal cell cancer clinical trials: results of the DATECAN project†. (2015) (26)
- Lymphocyte Subpopulations in Hodgkin’s Disease (1976) (25)
- New and modified interferon alfas: Preclinical and clinical data (2003) (25)
- Identification of prognostic genomic markers in patients with localized clear cell renal cell carcinoma (ccRCC). (2010) (25)
- Phase I study of WR-2721 and carboplatin. (1993) (25)
- A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer. (2000) (25)
- Use of Von-Hippel Lindau (VHL) mutation status to predict objective response to vascular endothelial growth factor (VEGF) -targeted therapy in metastatic renal cell carcinoma (RCC) (2007) (25)
- Thyroid function tests (TFTs) abnormalities in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib. (2006) (25)
- Safety and efficacy of sorafenib in elderly patients (pts) ≥65 years: A subset analysis from the Advanced Renal Cell Carcinoma Sorafenib (ARCCS) Expanded Access Program in North America (2008) (24)
- Molecular Mechanisms of Immune Dysfunction in Renal Cell Carcinoma (2000) (24)
- Interleukin 7 enhances the proliferation and effector function of tumor‐infiltrating lymphocytes from renal‐cell carcinoma (2009) (24)
- Thrombotic thrombocytopenic purpura: a review. (1982) (24)
- Randomized controlled trial of transfer factor in stage II malignant melanoma (1983) (24)
- Intermittent regional infusion of chemotherapy for pancreatic adenocarcinoma. Phase I and II pilot study. (1982) (24)
- Acute nonlymphocytic leukemia in patients receiving chemotherapy for nonmalignant diseases. (1980) (24)
- Approaches to managing carboplatin-induced thrombocytopenia: focus on the role of amifostine. (1999) (23)
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- Plasma exchange was more effective than plasma infusion for thrombotic thrombocytopenic purpura (1991) (1)
- Potential Clinical Applications in Cancer Therapy (1994) (1)
- A phase I trial of intrapleural recombinant human interferon α (rHuIFNα2b) in patients with malignant pleural effusions (2005) (1)
- Clinical trials in colorectal cancer: Experience of the Gastrointestinal Tumor Study Group and the Southwest Oncology Group (1987) (1)
- IMMUNOTHERAPY OF STAGE II MALIGNANT MELANOMA AND RENAL CELL CARCINOMA WITH TRANSFER FACTOR: CLINICAL RESULTS1 (1979) (1)
- High dose AZQ in renal cancer (1986) (1)
- Cancer Immunotherapy at the Crossroads (2004) (1)
- Phase II trial of weekly docetaxel and gemcitabine as first line therapy for patients with advanced non-small cell lung cancer. (2006) (1)
- Unclassified renal cell carcinoma (RCC): Analysis of clinical and pathologic features (2008) (1)
- Phase IV evaluation of clinical outcomes of PROCRIT in anemic cancer patients receiving chemotherapy (1994) (1)
- Clinical Management of Renal Cell Cancer (1990) (1)
- Mitoguazone in advanced renal carcinoma: a phase II trial of the Southwest Oncology Group. (1983) (1)
- Zometa® (Zoledronic acid) reduces skeletal complications in patients with bone metastases from renal cell carcinomain patients with bone metastases from renal cell carcinoma (2003) (1)
- Impaired Signal Transduction in Tumor Infiltrating T Cells from Patients with Renal Cell Carcinoma (1995) (1)
- Therapeutic Use of Recombinant Proteins (1999) (1)
- Receptor-Independent Pathways Apoptosis through Receptor-Dependent and Renal Cell Carcinoma Tumors Induce T Cell (2008) (1)
- Prolonged survival of a patient with Richter's syndrome. Report of a 10-year follow-up. (1981) (1)
- Highlights from: The 2008 meeting of the American Society of Clinical Oncology; May 30-June 3, 2008; Chicago, IL. (2008) (1)
- How I treat renal cell carcinoma. (2008) (1)
- Risk factor migration and survival: Analysis from international dataset of 3,748 metastatic renal cell carcinoma (mRCC) patients treated on clinical trials. (2011) (1)
- CarcinomasExpressed on Renal Cell B in T Cells by κ Degradation of NF (2013) (0)
- Medical Management of Metastatic Renal Cell Carcinoma (2015) (0)
- Book Review: Diagnostic and Therapeutic Antibodies (2000) (0)
- Acknowledgement to the Reviewers (2017) (0)
- 634: 4-Hydroxyneonal is Expressed on Renal Cell Carcinoma and it Promotes Apoptosis of T Lymphocytes (2005) (0)
- Phase II trial of Fluorouracil, Leucovorin and Interferon-α (1994) (0)
- A phase Ib trial of an anti-idiotypic vaccine for Lewis Y (IGN 301) administered subcutaneously in patients with refractory solid tumors. (2004) (0)
- Combination Therapy of Renal Cell Carcinoma with Interleukin-2 and Interferon Alpha: The Cleveland Clinic Experience (1991) (0)
- Alterations in NF k B Activation in T Lymphocytes of Patients With Renal Cell Carcinoma (1999) (0)
- Clinical Results and Characterization of Tumor-infiltrating Lymphocytes with or without Recombinant Interleukin 2 in Human Metastatic Renal Cell Carcinoma 1 (2006) (0)
- The Cost of Hope: a candid roundtable discussion. (2013) (0)
- The Role of Gangliosides in Renal Cell Carcinoma (2009) (0)
- Durable complete responses and near complete responses to sunitinib in metastatic renal cell carcinoma (2007) (0)
- Chemotherapy for Metastatic Parathyroid Carcinoma-Reply (1984) (0)
- VHL gene mutation and hypermethylation in patients with renal cell carcinoma: Preliminary results and clinical correlation (2005) (0)
- Effects of interleukin-12 on interferon-gamma production by peripheral blood and tumor infiltrating T-lymphocytes from renal cell carcinoma patients: Evidence of impaired secretion (1996) (0)
- INHIBITION OF NF kappa B BINDING IN T CELLS OF PATIENTS WITH RENAL CELL CARCINOMA (RCC): THE ROLE OF IMMUNOSUPPRESSIVE GANGLIOSIDES (1999) (0)
- Highlights from: The 2008 Genitourinary Cancers Symposium; February 14-16, 2008; San Francisco, CA (2008) (0)
- 631: TNFα and Gangliosides Work Synergistically to Induce Apoptosis of T Lymphocytes in Renal Cell Carcinoma (2005) (0)
- Bladder Cancer and Current Evidence for Treatment December (2017) (0)
- Dilemmas in the Management of Treatment-Naïve Patients With Metastatic Renal Cell Carcinoma (2010) (0)
- Carcinoma of the Unknown Primary (2006) (0)
- Functional Imaging of Renal Cell Carcinoma (2008) (0)
- Renal Cell Carcinoma Metastatic to the Pancreas: Clinical and Therapeutic Aspects (2008) (0)
- Clinical Cancer esearch ing , Diagnosis , Prognosis markers Predicting Outcome in Patients with Advanced al Cell Carcinoma : Results from Sorafenib Phase III atment Approaches in Renal Cancer R bal Evaluation (2010) (0)
- Signal Transduction Inhibitors in Renal Cell Carcinoma (2008) (0)
- Targeted Therapies for Renal Cell Carcinoma (2011) (0)
- Nonsurgical Management of Metastatic Renal Cell Carcinoma (2008) (0)
- Book Review: Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What can be Done. (2004) (0)
- Randomized trial of MAID chemotherapy with G-CSF alone or with G-CSF plus varying doses of interleukin-6 (1996) (0)
- Targeted therapy for renal cell carcinoma (2011) (0)
- Necessary for IL-12-Mediated Regression of the The CXC Chemokines IP-10 and Mig Are (2013) (0)
- Targeted si-RNA mediated down-regulation of topoisomerase II α or β isozymes defines selectivity to inhibitors of the enzyme (2005) (0)
- Subject Index Vol. 78, 2010 (2010) (0)
- Suppression of tcr-cd3 linked tyrosine phosphorylation of normal peripheral blood T cells by tumor supernatants from renal cell carcinoma (RCC) (1996) (0)
- Retroperitoneal Extragonadal Germ Cell Tumors Associated with Unrecognized Testicular Cancer (1987) (0)
- in the Treatment of Thrombotic (2016) (0)
- Targeted therapy for cytokine-refractory metastatic renal cell carcinoma, and treatment in the community. (2006) (0)
- Hematologic effects of recombinant human Interleukin-6 (rhIL-6) in sarcoma patients receiving maid chemotherapy: phase I trial (1994) (0)
- 1006 ORAL Prognostic Factors for Progression-free Survival (PFS), Overall Survival (OS), and Long-term OS (LT-OS) With Sunitinib in 1,059 Patients, Treated on Clinical Trials, With Metastatic Renal Cell Carcinoma (mRCC) (2011) (0)
- APhase I Pharmacokinetic and Pharmacodynamic Study of S-3304 , a Novel Matrix Metalloproteinase Inhibitor , in Patients with Advanced and Refractory SolidTumors (2007) (0)
- Thanks to Reviewers2003 (2003) (0)
- Commentary: Meta-Analyses Reporting the Prognostic Value of Androgen Receptor Splice Variant 7 in Castration-Resistant Prostate Cancer (2020) (0)
- Translating Biology to Clinical Practice: Evolving Strategies for the Treatment of Renal Cell Carcinoma (2008) (0)
- GM2 overexpression in renal cell carcinoma: potential role in tumor induced immune dysfunction (2005) (0)
- APhase I Study with Neratinib ( HKI-272 ) , an Irreversible Pan ErbB Receptor Tyrosine Kinase Inhibitor , in Patients with Solid Tumors (2009) (0)
- Phase I and Pharmacology Studies (2004) (0)
- The 43rd Annual Meeting of the American Society of Clinical Oncology (2007) (0)
- Expression of caveolin-1 in renal neoplasms. (2006) (0)
- Thanks to Reviewers2002 (2002) (0)
- Sorafenib in Renal Cell Carcinoma (2009) (0)
- The role of sunitinib in metastatic renal cell carcinoma (2008) (0)
- The von Hippel Lindau (VHL) gene status is not always identical in paired primary (P) and metastatic (M) lesion in patients with clear cell renal cell carcinoma (CCRCC) (2008) (0)
- Abstract A54: Potential mechanisms of resistance to targeted agents in human clear cell renal cell carcinoma (2012) (0)
- Weekly docetaxel-gemcitabine as first-line treatment in advanced non-small cell lung cancer: Preliminary results of a phase II study. (2004) (0)
- Combination chemotherapy for metastatic carcinoma of the ampulla of Vater—report of three cases (1984) (0)
- P57 Elderly patients with advanced renal cell carcinoma (RCC): combined experience with sorafenib from the randomized phase III TARGET and the European (EU) and North American (NA) Open-Access (ARCCS) trials (2009) (0)
- ACTIVATION INDUCED CELL DEATH (AICD) IN T LYMPHOCYTES FROM PATIENTS WITH RENAL CELL CARCINOMA (RCC): A POTENTIAL MECHANISM OF TUMOR IMMUNE ESCAPE (1999) (0)
- RAD-001: future directions (2009) (0)
- Prostaglandin e2 (pge2) modulates the expression of jak3 in naive and activated t lymphocytes (1996) (0)
- Renal Cell Carcinoma: Development of a New Treatment Paradigm (2006) (0)
- Diagnostic and Management Issues in Gallbladder Carcinoma (2017) (0)
- 2008 Best of the Rest in Urological Survey (2008) (0)
- IL-2 Based Combination Therapy of Malignant Disease: Summary of the Phase I Experience at the Cleveland Clinic (1992) (0)
- Acknowledgement of Reviewers (2004) (0)
- Acknowledgement to the Reviewers (2017) (0)
- 493 POSTER Down regulation of topoisomerase IIβ in myeloid leukemia cell lines leads to activation of apoptosis following all-trans retinoic acid-induced differentiation/growth arrest (2006) (0)
- Biochemical modulation of fluorouracil in patients with metastatic colorectal cancer (2001) (0)
- Cytokine Therapy of Metastatic Renal Cell Carcinoma: The Cleveland Clinic Experience (1995) (0)
- Intra-ovarian action of progesterone in monkeys: characterization of ovarian progesterone receptor distribution. (1996) (0)
- Target identification by phosphoproteomics: RIN1 modulation of sorafenib-induced cytotoxicity in renal cell carcinoma. (2009) (0)
- Renal Cell Carcinomas Promotes T Cell Induction of GM 2 Expression on α TNF-and (2007) (0)
- Phosphorylation of tyrosine 656 in topoisomerase IIβ is required for enzymatic activity and anti-tumor drug sensitivity (2007) (0)
- Molecular genetic events associated with renal cell carninoma and its implication to treatment by molecular target therapy (2010) (0)
- Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma. (2023) (0)
- Is Pazopanib Safe and Efficacious in Patients with Metastatic Renal Cell Carcinoma? (2010) (0)
- Combined-modality Treatment of Renal Cell Carcinoma (2000) (0)
- Acknowledgment to Referees (2014) (0)
- Poor Risk Renal Cell Carcinoma Patients: Role of New Agents (2007) (0)
- Alterations in T-Cell Signaling Pathways and Increased Sensitivity to Apoptosis (2004) (0)
- Comprar Renal Cell Carcinoma | Ronald M. Bukowski | 9781588297372 | Humana Press (2009) (0)
- Highlights from: The 43rd Annual Meeting of the American Society of Clinical Oncology; June 1-5, 2007; Chicago, IL (2007) (0)
- Phase I Clinical Trial of Interleukin 2 and a-Interferon: Toxicity and Immunologie Effects1 (2006) (0)
- Cell Carcinoma? Can We Predict Long-Term Survival After Pulmonary Metastasectomy for Renal (2013) (0)
- Suppressor Cells in Oncology (2018) (0)
- Original article Phase II trial of capecitabine and rHu-interferon--2a in patients with metastatic renal cell carcinoma, limited efficacy, and moderate toxicity (2007) (0)
- Contents Vol. 78, 2010 (2010) (0)
- 233 A phase IV study of epoetin alfa examining clinical outcomes in anaemic cancer patients receiving chemotherapy (1995) (0)
- 203 Modulation of DNA damage induced apoptosis by the proteasome inhibitor bortezomib (PS) in human colorectal and non-small cell lung cancer cells is p53-dependent and NK-kB-independent (2004) (0)
- Activation of human peripheral blood immune cells in vitro by sodium stibogluconate (SSG) and SSG/IL-2 combination. (2006) (0)
- Caspase-1 and-3 Apoptosis Without Detectable Activation of Lymphocytes Induces Caspase-Dependent B Activity in Human T κ Inhibition of NF (1999) (0)
- Optimizing utilization of targeted therapies in genitourinary cancers. (2008) (0)
- Meet Our Editorial Board Member (2018) (0)
- Strategies for selective modulation of Vinca alkaloid cytotoxicity by the anti-epileptic phenytoin: experimental and clinical experience (1994) (0)
- Book Review: Suicide Gene Therapy: Methods and Reviews. (2004) (0)
- Is temsirolimus more safe and effective than interferon α for the treatment of advanced renal cell carcinoma? (2007) (0)
- Development of novel signal transduction inhibitors: Recent phase I trials (2002) (0)
- Efficacy and safety of sorafenib in patients with advanced clear-cell renal cell carcinoma (RCC) with diabetes: Results from the phase III TARGET study. (2009) (0)
- Abstract 1626: Tyrosine phosphorylation of RIN1 modulates the anti-proliferative effects of sorafenib and sunitinib in renal cell carcinoma (RCC) (2010) (0)
- Phase I study of interleukin-4 (rHuIL-4) combined with chemotherapy in gastrointestinal (GI) malignancies (1997) (0)
- Pegylated I nterferon A lfa-2b T reatment f or P atients W ith Solid T umors: A P hase I /II S tudy (2002) (0)
- Nigro regimen treatment of squamous cell cancer of the anus (2007) (0)
- Immunologic studies of peripheral blood lymphocytes and lymph nodes in Hodgkin's disease. A preliminary report. (1985) (0)
- Sorafenib treatment of clear-cell renal cell carcinoma (CCRCC) and colorectal carcinoma (CRC) cells: Differential effects on gene expression and cell death pathways (2007) (0)
- Renal cell carcinoma: immunotherapy revisited (2011) (0)
- Defining Clinical Endpoints in Renal Cell Carcinoma (2006) (0)
- Imag Bio Ren Tre Glo Carol Abst (2010) (0)
- Immunologic studies of alveolar macrophages from patients with metastatic renal cell carcinoma. (1990) (0)
- An oral fluoropyrimidine prodrug with activity in colorectal cancer (2001) (0)
- 48 POSTER Distinct gene expression profiles and cell death pathways in clear-cell renal cell carcinoma (CCRCC) and colorectal carcinoma (CRC) cells:r elationship to hypoxia, von Hippel Lindau protein (pVHL) expression and anti-tumor activity of sorafenib (2006) (0)
- Bladder Cancer and Current Evidence for Treatment (2007) (0)
- Referee acknowledgement for 2019 (2020) (0)
- Specific chemokine expression in vivo correlates with highly selective leukocytic infiltration (1994) (0)
- Suppression of nficb activation in normal T cells by soluble products from renal cell carcinoma explants (1996) (0)
- S9 Renal Cell Carcinoma : Developing Therapeutic Approaches(Keynote Lecture,Symposium 9「Recent Trend of Treatment for Metastatic Renal Cell Carcinoma」) (2006) (0)
- GM2 Expression in Renal Cell Carcinoma Cells and T Lymphocytes: Potential Role in Tumor-Induced Immune Dysfunction (2005) (0)
- Book Review: Renal Cell Carcinoma (2000) (0)
- Development of a new treatment paradigm has stimulated the interest of investigators and clinicians in renal cell carcinoma (2011) (0)
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