Ronald M. Evans

Q: What Schools Are Affiliated With Ronald M. Evans

Ronald M. Evans is affiliated with the following schools: Duke University, Rice University, Boston University, McGill University, University of California, Irvine, University of Sydney, University of California, San Diego, University of California, Los Angeles, Massachusetts Institute of Technology, Baylor College of Medicine, Cornell University, University of Pittsburgh, University of North Carolina at Chapel Hill

Ronald M. Evans's AcademicInfluence.com Rankings

Ronald M. Evans

Biology

#438

World Rank

#785

Historical Rank

#263

USA Rank

Developmental Biology

World Rank

Historical Rank

USA Rank

Molecular Biology

#56

World Rank

#57

Historical Rank

#40

USA Rank

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Biology

Ronald M. Evans's Degrees

Bachelors Biology University of California, Irvine

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Why Is Ronald M. Evans Influential?

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According to Wikipedia, Ronald Mark Evans is an American Biologist, Professor and Head of the Salk’s Gene Expression Laboratory, and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute for Biological Studies in La Jolla, California and a Howard Hughes Medical Institute Investigator. Dr. Ronald M. Evans is known for his original discoveries of nuclear hormone receptors , a special class of transcriptional factor, and the elucidation of their universal mechanism of action, a process that governs how lipophilic hormones and drugs regulate virtually every developmental and metabolic pathway in animals and humans. Nowadays, NRs are among the most widely investigated group of pharmaceutical targets in the world, already yielding benefits in drug discovery for cancer, muscular dystrophies, osteoporosis, type II diabetes, obesity, and cardiovascular diseases. His current research focuses on the function of nuclear hormone signaling and their function in metabolism and cancer.

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Ronald M. Evans's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The steroid and thyroid hormone receptor superfamily. (1988) (7164)
The nuclear receptor superfamily: The second decade (1995) (6907)
The RXR heterodimers and orphan receptors (1995) (3239)
15-Deoxy-Δ 12,14-Prostaglandin J 2 is a ligand for the adipocyte determination factor PPARγ (1995) (2718)
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing (1983) (2215)
Nuclear receptors and lipid physiology: opening the X-files. (2001) (2060)
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ (1997) (1998)
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products (1982) (1973)
Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ (1998) (1889)
Identification of a receptor for the morphogen retinoic acid (1987) (1878)
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. (1987) (1811)
Primary structure and expression of a functional human glucocorticoid receptor cDNA (1985) (1784)
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors (1992) (1748)
PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL (1998) (1713)
PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development (1999) (1712)
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor (1992) (1704)
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors (1991) (1597)
Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300 (1997) (1530)
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells (2011) (1522)
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML (1991) (1484)
Nuclear receptor that identifies a novel retinoic acid response pathway (1990) (1443)
PPARγ signaling and metabolism: the good, the bad and the future (2013) (1417)
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. (1994) (1398)
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling (1992) (1382)
A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1376)
The c-erb-A gene encodes a thyroid hormone receptor (1986) (1344)
Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase (1997) (1337)
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes (1982) (1303)
A transcriptional co-repressor that interacts with nuclear hormone receptors (1995) (1290)
Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity (2003) (1222)
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor (1990) (1208)
A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis (2001) (1176)
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. (1992) (1154)
A Unified Nomenclature System for the Nuclear Receptor Superfamily (1999) (1152)
Role of the histone deacetylase complex in acute promyelocytic leukaemia (1998) (1126)
Regulation of Muscle Fiber Type and Running Endurance by PPARδ (2004) (1105)
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. (1995) (1104)
LXR, a nuclear receptor that defines a distinct retinoid response pathway. (1995) (1100)
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation (2001) (1079)
Identification of a nuclear receptor that is activated by farnesol metabolites (1995) (1070)
Vitamin D Receptor As an Intestinal Bile Acid Sensor (2002) (1023)
AMPK and PPARδ Agonists Are Exercise Mimetics (2008) (981)
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle (2003) (979)
Role of CBP/P300 in nuclear receptor signalling (1996) (960)
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network (2006) (958)
SXR, a novel steroid and xenobiotic-sensing nuclear receptor. (1998) (940)
Nuclear Receptor Expression Links the Circadian Clock to Metabolism (2006) (918)
PPAR gamma is required for placental, cardiac, and adipose tissue development. (1999) (911)
Determinants of target gene specificity for steroid/thyroid hormone receptors (1989) (909)
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes (1993) (903)
Terminal differentiation of human breast cancer through PPAR gamma. (1998) (900)
Ecdysone-inducible gene expression in mammalian cells and transgenic mice. (1996) (869)
Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. (2003) (863)
Functional domains of the human glucocorticoid receptor (1986) (844)
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein (1994) (837)
Nuclear Receptors, RXR, and the Big Bang (2014) (825)
Identification of a new class of steroid hormone receptors (1988) (803)
AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation (2009) (800)
Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ (2012) (799)
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. (1997) (776)
Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy (2014) (776)
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids (2001) (747)
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion (2016) (744)
Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation (1992) (704)
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. (1997) (691)
Humanized xenobiotic response in mice expressing nuclear receptor SXR (2000) (677)
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. (1994) (671)
Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase (1999) (663)
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. (1998) (655)
Multiple and cooperative trans-activation domains of the human glucocorticoid receptor (1988) (643)
Unique response pathways are established by allosteric interactions among nuclear hormone receptors (1995) (634)
A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR (1991) (629)
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. (1998) (629)
Zinc fingers: Gilt by association (1988) (626)
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. (2001) (617)
Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. (1985) (610)
Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ (2003) (607)
Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer (2001) (599)
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. (2003) (597)
PPARδ: a dagger in the heart of the metabolic syndrome (2006) (583)
The neuronal mineralocorticoid eeceptor as a mediator of glucocorticoid response (1988) (565)
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist (1989) (558)
Structural determinants of nuclear receptor assembly on DNA direct repeats (1995) (551)
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance (2012) (549)
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. (2000) (547)
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance (2008) (544)
Pitx2 determines left–right asymmetry of internal organs in vertebrates (1998) (530)
A role for adult TLX-positive neural stem cells in learning and behaviour (2008) (530)
Retinoic acid is a negative regulator of AP-1-responsive genes. (1991) (528)
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance (2015) (513)
Muscle-specific Pparg deletion causes insulin resistance (2003) (509)
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response (2013) (507)
Retinoic acid and thyroid hormone induce gene expression through a common responsive element (1988) (506)
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 (2004) (503)
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis (2011) (500)
Androstane metabolites bind to and deactivate the nuclear receptor CAR-β (1998) (498)
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. (1999) (497)
Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors. (1994) (493)
Differential activation of adipogenesis by multiple PPAR isoforms. (1996) (486)
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor (2011) (483)
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription (2013) (482)
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming (2011) (473)
International Union of Pharmacology. LXIII. Retinoid X Receptors (2006) (472)
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy (2004) (463)
Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene (1990) (460)
PPAR-γ regulates osteoclastogenesis in mice (2007) (454)
Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene. (1990) (447)
PPARδ regulates glucose metabolism and insulin sensitivity (2006) (447)
Activators of the nuclear receptor PPARγ enhance colon polyp formation (1998) (442)
Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor (1987) (436)
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. (2000) (429)
Mechanism of corepressor binding and release from nuclear hormone receptors. (1999) (428)
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators (2002) (416)
Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism (1996) (408)
The histone acetylase PCAF is a nuclear receptor coactivator. (1998) (407)
Expression and function of orphan nuclear receptor TLX in adult neural stem cells (2004) (405)
Complex transcriptional units: diversity in gene expression by alternative RNA processing. (1986) (384)
Determinants for selective RAR and TR recognition of direct repeat HREs. (1993) (383)
Stimulation of noradrenergic sympathetic outflow by calcitonin gene-related peptide (1983) (379)
Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency (2000) (376)
Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. (1987) (376)
Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor (1990) (375)
International Union of Pharmacology. LX. Retinoic Acid Receptors (2006) (375)
Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. (1984) (369)
A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity (1999) (362)
STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells (2010) (361)
Genome-wide Orchestration of Cardiac Functions by the Orphan Nuclear Receptors ERRα and γ (2007) (359)
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor (2003) (356)
A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. (2003) (351)
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. (1997) (343)
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. (1992) (338)
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. (2001) (337)
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product (1985) (332)
A Novel Pregnane X Receptor-mediated and Sterol Regulatory Element-binding Protein-independent Lipogenic Pathway* (2006) (331)
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice (2012) (330)
Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. (1996) (330)
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity (2017) (327)
Orphan nuclear receptors--new ligands and new possibilities. (1998) (313)
PPAR delta: a dagger in the heart of the metabolic syndrome. (2006) (312)
The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling (2002) (312)
Transgenic mice with inducible dwarfism (1989) (312)
An inhibitor of the protein kinases TBK1/IKKε improves obesity-related metabolic dysfunctions (2013) (311)
Role for Peroxisome Proliferator-Activated Receptor &agr; in Oxidized Phospholipid–Induced Synthesis of Monocyte Chemotactic Protein-1 and Interleukin-8 by Endothelial Cells (2000) (306)
Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor (1983) (302)
Coincidence of the promoter and capped 5′ terminus of RNA from the adenovirus 2 major late transcription unit (1978) (300)
A Gpr120 Selective Agonist Improves Insulin Resistance and Chronic Inflammation (2014) (299)
An Essential Role for Retinoid Receptors RARβ and RXRγ In Long-Term Potentiation and Depression (1998) (296)
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. (2004) (295)
TRB3 Links the E3 Ubiquitin Ligase COP1 to Lipid Metabolism (2006) (295)
Nuclear receptors: Decoding metabolic disease (2008) (292)
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding. (1993) (292)
PPARδ is a very low-density lipoprotein sensor in macrophages (2003) (290)
Independent effects of growth hormone releasing factor on growth hormone release and gene transcription (1985) (288)
The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. (1997) (283)
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. (2007) (281)
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone (1987) (277)
PPAR-gamma regulates osteoclastogenesis in mice. (2007) (276)
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. (1999) (275)
Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. (1992) (275)
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR) (2002) (269)
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body. (1998) (268)
Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth (1985) (265)
The Peroxisome Proliferator‐activated Receptors: Ligands and Activators a (1996) (265)
Regulation of MEF2 by Histone Deacetylase 4- and SIRT1 Deacetylase-Mediated Lysine Modifications (2005) (265)
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. (2007) (263)
Targeting of an inducible toxic phenotype in animal cells. (1988) (262)
Production of mRNA in chinese hamster cells: Relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences (1979) (260)
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. (1996) (257)
PPARγ activation in adipocytes is sufficient for systemic insulin sensitization (2009) (255)
The ruff figural fluency test: A normative study with adults (1987) (253)
Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression. (1982) (252)
AMPK and PPARδ Agonists Are Exercise Mimetics (2008) (252)
PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis (2007) (251)
Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity (2001) (248)
A Nuclear Receptor Atlas: macrophage activation. (2005) (248)
Retinoic acid is required early during adult neurogenesis in the dentate gyrus. (2006) (246)
An essential role for retinoid signaling in anteroposterior neural patterning. (1997) (244)
Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. (2010) (243)
The nuclear receptor superfamily: a rosetta stone for physiology. (2005) (242)
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms (1986) (241)
The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. (1998) (240)
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection. (1985) (236)
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. (2007) (234)
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. (2013) (234)
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. (2004) (232)
A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis (2012) (232)
Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice* (2004) (231)
Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling (231)
Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers. (2000) (229)
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation (2007) (229)
NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function (2011) (224)
PPARdelta regulates glucose metabolism and insulin sensitivity. (2006) (224)
Orphan Nuclear Receptors: The Exotics of Xenobiotics* (2001) (223)
Activators of the nuclear receptor PPARgamma enhance colon polyp formation. (1998) (221)
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring (2019) (220)
The Constitutive Androstane Receptor and Pregnane X Receptor Function Coordinately to Prevent Bile Acid-induced Hepatotoxicity* (2004) (220)
Alternative RNA processing: determining neuronal phenotype. (1984) (219)
FXR Regulates Intestinal Cancer Stem Cell Proliferation (2019) (218)
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis (2017) (218)
Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. (1988) (217)
PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis (2008) (217)
A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex. (1988) (217)
Global chemical effects of the microbiome include new bile-acid conjugations (2020) (215)
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. (2003) (212)
Orphan nuclear receptor TLX activates Wnt/β-catenin signalling to stimulate neural stem cell proliferation and self-renewal (2010) (212)
SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. (1999) (209)
Inhibin A-subunit cDNAs from porcine ovary and human placenta. (1986) (209)
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. (2005) (205)
PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. (2010) (203)
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. (2007) (200)
A molecular framework for the actions of glucocorticoid hormones in the nervous system (1989) (199)
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer (2014) (197)
PPARδ regulates multiple proinflammatory pathways to suppress atherosclerosis (2008) (193)
Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling. (1999) (192)
RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice. (1996) (191)
Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor. (1993) (189)
Isolation and Characterization of Mammalian HDAC10, a Novel Histone Deacetylase* (2002) (189)
Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene. (1993) (187)
Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx (1994) (186)
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease (2019) (186)
Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper. (1991) (183)
HATs on and beyond chromatin. (2001) (183)
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors. (1994) (182)
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice. (1995) (181)
Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants. (1993) (181)
The initiation sites for RNA transcription in Ad2 DNA (1977) (178)
Unique forms of human and mouse nuclear receptor corepressor SMRT. (1999) (178)
Epidermal growth factor rapidly stimulates prolactin gene transcription (1982) (177)
Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. (1989) (177)
Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells (2010) (175)
Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. (1990) (174)
Transcriptional regulation in acute promyelocytic leukemia (2001) (174)
PPARs and ERRs: molecular mediators of mitochondrial metabolism. (2015) (172)
The commonly used antimicrobial additive triclosan is a liver tumor promoter (2014) (171)
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites (1984) (169)
PPARγ signaling exacerbates mammary gland tumor development (2004) (168)
A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line. (1992) (168)
Nuclear Receptors in Sicily: All in the Famiglia (1997) (164)
Depletion of Fat Tregs Prevents Age-Associated Insulin Resistance (2015) (160)
Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression (1987) (160)
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis. (2020) (159)
Modulation of glucocorticoid receptor function by protein kinase A. (1992) (159)
Activation of specific RXR heterodimers by an antagonist of RXR homodimers (1996) (158)
A methylation-mediator complex in hormone signaling. (2004) (158)
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice (2018) (156)
Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling (2015) (156)
Benefit of farnesoid X receptor inhibition in obstructive cholestasis. (2006) (154)
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. (2000) (152)
Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes (1986) (152)
A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene. (1988) (151)
Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage. (2007) (151)
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. (2011) (149)
BRD4 is a novel therapeutic target for liver fibrosis (2015) (149)
Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2. (1999) (149)
The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis. (1992) (148)
Further Psychometric Evaluation and Revision of the Mayo‐Portland Adaptability Inventory in a National Sample (2003) (147)
Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors (2004) (146)
Expression-cloning and sequence of a cDNA encoding human growth hormone-releasing factor (1983) (145)
Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states (1996) (145)
Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state. (1991) (145)
Identification of a nuclear domain with deacetylase activity. (2000) (143)
Characterization of cDNA and genomic clones encoding the precursor to rat hypothalamic growth hormone-releasing factor (1985) (142)
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors. (2021) (142)
Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters. (1986) (142)
A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression. (2019) (141)
The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. (2001) (140)
Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice (2014) (139)
Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs (2015) (138)
Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors. (1989) (136)
Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. (2000) (134)
Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon (2003) (134)
Immune evasive human islet-like organoids ameliorate diabetes (2020) (133)
An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. (1998) (133)
Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg. (1992) (133)
The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. (1997) (133)
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. (2020) (132)
PPARδ Promotes Running Endurance by Preserving Glucose. (2017) (132)
Gene encoding human growth hormone-releasing factor precursor: structure, sequence, and chromosomal assignment. (1985) (130)
PPARdelta is a very low-density lipoprotein sensor in macrophages. (2003) (129)
Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression. (1985) (128)
Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist (2012) (128)
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. (2006) (127)
ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer (2016) (125)
Efficient insertion of genes into the mouse germ line via retroviral vectors. (1985) (124)
ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells. (2016) (124)
Polypeptide hormone regulation of gene expression. Thyrotropin-releasing hormone rapidly stimulates both transcription of the prolactin gene and the phosphorylation of a specific nuclear protein. (1983) (123)
The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. (2000) (122)
Inducible gene expression in mammalian cells and transgenic mice. (1997) (121)
Vitamin D Switches BAF Complexes to Protect β Cells (2018) (121)
Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo. (1995) (121)
“Don't Know Much Bile-ology” (2000) (118)
Identification of ligands and coligands for the ecdysone-regulated gene switch. (2000) (116)
Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors. (1996) (116)
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors. (1996) (114)
Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation (2016) (114)
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. (2009) (113)
Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation. (1995) (112)
ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. (2015) (109)
Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor. (1991) (108)
Compound mutants for retinoic acid receptor (RAR)β and RARα1 reveal developmental functions for multiple RARβ isoforms (1996) (108)
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis. (2012) (108)
Retinoid-dependent pathways suppress myocardial cell hypertrophy. (1995) (108)
Ligation independent cloning irrespective of restriction site compatibility. (1997) (107)
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1 (2017) (106)
Regulation of neuroendocrine gene expression by alternative RNA processing. Colocalization of calcitonin and calcitonin gene-related peptide in thyroid C-cells. (1985) (105)
Stromal cues regulate the pancreatic cancer epigenome and metabolome (2017) (105)
Transgenic expression of PML/RARalpha impairs myelopoiesis. (1996) (105)
Fibroblast Growth Factor Signaling in Metabolic Regulation (2016) (105)
Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes (1985) (104)
Treatment of chronic closed head injury with psychostimulant drugs: a controlled case study and an appropriate evaluation procedure. (1987) (103)
Novel retinoic acid receptor ligands in Xenopus embryos. (1996) (103)
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. (2017) (102)
Coexpression of nuclear receptor partners increases their solubility and biological activities. (1997) (102)
Peroxisome Proliferator-Activated Receptor-γ-Deficient Heterozygous Mice Develop an Exacerbated Neural Antigen-Induced Th1 Response and Experimental Allergic Encephalomyelitis 1 (2003) (101)
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. (2006) (100)
Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein (1988) (100)
Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration (2016) (100)
Peroxisome proliferator-activated receptor δ promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage (2006) (99)
Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition. (2003) (98)
Calcitonin mRNA polymorphism: peptide switching associated with alternative RNA splicing events. (1982) (98)
Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk (2007) (98)
Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo (1995) (97)
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis (2008) (96)
A functional retinoic acid receptor encoded by the gene on human chromosome 12. (1990) (96)
Nuclear receptors, metabolism, and the circadian clock. (2007) (94)
Molecular mechanisms of phorbol ester, thyrotropin-releasing hormone, and growth factor stimulation of prolactin gene transcription. (1985) (93)
PPAR gamma signaling exacerbates mammary gland tumor development. (2004) (92)
Automatic Detection vs Controlled Search: A Paper-and-Pencil Approach (1986) (92)
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. (2005) (92)
The Drosophila gene knirps-related is a member of the steroid-receptor gene superf amily (1988) (91)
Altered expression of the calcitonin gene associated with RNA polymorphism (1981) (91)
Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb (1989) (91)
The germ cell nuclear factor mGCNF is expressed in the developing nervous system. (1997) (90)
Estrogen-Related Receptor α (ERRα) and ERRγ Are Essential Coordinators of Cardiac Metabolism and Function (2015) (90)
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. (2019) (90)
Cyclic AMP regulation of eukaryotic gene transcription by two discrete molecular mechanisms. (1985) (88)
Exercise Mimetics: Impact on Health and Performance. (2017) (88)
Tumor suppressor protein (p)53, is a regulator of NF-κB repression by the glucocorticoid receptor (2011) (86)
Signals and Receptors. (2016) (86)
The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages (2014) (85)
Epigenetic codes of PPARγ in metabolic disease (2011) (85)
A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection. (2003) (84)
Deficiency of PPARβ/δ in the Epidermis Results in Defective Cutaneous Permeability Barrier Homeostasis and Increased Inflammation (2008) (84)
Corepressors and nuclear hormone receptor function. (2001) (84)
Pituitary hyperplasia induced by ectopic expression of nerve growth factor. (1992) (83)
Impaired verbal and figural fluency after head injury. (1986) (82)
BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. (1998) (81)
Infectious and selectable retrovirus containing an inducible rat growth hormone minigene. (1984) (81)
Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells (2011) (81)
Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor. (1992) (80)
A retinoic acid-triggered cascade of HOXB1 gene activation. (1995) (79)
A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis (2015) (78)
Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor (1996) (77)
Peroxisome proliferator-activated receptor-γ in macrophage lipid homeostasis (2002) (77)
Peroxisome Proliferator-Activated Receptor γ Controls Muc1 Transcription in Trophoblasts (2004) (77)
Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations. (1997) (77)
The Structural Basis for the Specificity of Retinoid-X Receptor-selective Agonists: New Insights Into the Role of Helix H12* (2002) (76)
A mouse cdc25 homolog is differentially and developmentally expressed. (1992) (75)
Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. (1982) (75)
Molecular genetics of acute promyelocytic leukemia. (1999) (75)
Alteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-α (PPARα) Generates a PPARδ Phenotype (2000) (75)
Phosphotryptic peptide analysis of human progesterone receptor. New phosphorylated sites formed in nuclei after hormone treatment. (1989) (74)
PPARs and LXRs: atherosclerosis goes nuclear (2004) (74)
Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging (2015) (73)
Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. (2003) (72)
Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity (2017) (71)
CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity. (2017) (70)
The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock (2007) (70)
Forced retinoic acid receptor α homodimers prime mice for APL-like leukemia (2006) (70)
Characterization of rat calcitonin mRNA. (1980) (70)
Transcriptional regulation of the c‐jun gene by retinoic acid and E1A during differentiation of F9 cells. (1992) (68)
Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos. (1998) (68)
The farnesyl protein transferase inhibitor BZA-5B blocks farnesylation of nuclear lamins and p21ras but does not affect their function or localization. (1995) (68)
Nuclear receptors rock around the clock (2014) (68)
Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells. (1992) (67)
Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects. (1995) (67)
FGF1 — a new weapon to control type 2 diabetes mellitus (2017) (67)
Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB‐binding protein (2004) (66)
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice[S] (2013) (66)
Metabolic Crosstalk: Molecular Links Between Glycogen and Lipid Metabolism in Obesity (2014) (66)
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S] (2012) (63)
Unexpected Thymic Hyperplasia in Transgenic Mice Harboring a Neuronal Promoter Fused with Simian Virus 40 Large T Antigen (1987) (63)
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet (2011) (62)
Evidence for two distinct retinoic acid response pathways for HOXB1 gene regulation. (1995) (62)
Premature termination during adenovirus transcription (1979) (62)
Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease (2013) (62)
Thyroid Hormone Receptor Repression Linked to Type I Pneumocyte Associated Respiratory Distress Syndrome (2011) (62)
Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma (2017) (61)
RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype (2019) (60)
The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response (2001) (60)
Thyrotropin-releasing hormone exerts rapid nuclear effects to increase production of the primary prolactin mRNA transcript. (1981) (60)
Stimulant treatment for the neurobehavioural sequelae of traumatic brain injury. (1988) (59)
ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. (2010) (58)
Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence. (1978) (58)
Pharmaceutical use of mouse models humanized for the xenobiotic receptor. (2002) (58)
SRY-box-containing Gene 2 Regulation of Nuclear Receptor Tailless (Tlx) Transcription in Adult Neural Stem Cells* (2011) (58)
Carbamazepine in pediatric psychiatry. (1987) (58)
Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein (1995) (56)
Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance (2011) (56)
The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. (2008) (56)
Circadian clock cryptochrome proteins regulate autoimmunity (2017) (56)
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages (2016) (55)
Visible light reduces C. elegans longevity (2018) (54)
Identification of receptors for retinoids as members of the steroid and thyroid hormone receptor family. (1990) (54)
Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk. (2007) (53)
Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ (2017) (53)
Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. (2006) (53)
Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression. (1984) (53)
A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation. (1997) (52)
Retinoic acid and retinoic acid receptors in development (1995) (52)
Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alpha. (1993) (52)
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease (2016) (52)
The PML nuclear compartment and cancer. (1996) (51)
Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases (2016) (51)
Pregnane-X-Receptor Controls Hepatic Glucuronidation During Pregnancy and Neonatal Development in Humanized UGT1 Mice (2012) (49)
Transgenic mice: applications to the study of the nervous system. (1988) (49)
Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice. (2008) (49)
Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. (2010) (49)
High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice (2015) (48)
Evidence that Shh cooperates with a retinoic acid inducible co-factor to establish ZPA-like activity. (1996) (48)
Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response. (1995) (47)
Effect of heterozygous PPARγ deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding (2003) (47)
Nuclear Hormone Receptors Activate Direct, Inverted, and Everted Repeats a (1995) (46)
Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. (2008) (45)
Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. (2003) (44)
Clinical and neuropsychological effects of the novel antidepressant bupropion. (1988) (44)
Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. (2015) (42)
ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY (2005) (42)
Obesity alters pathology and treatment response in inflammatory disease (2022) (41)
Acetylation and methylation in nuclear receptor gene activation. (2003) (41)
O-GlcNAc Transferase Is Involved in Glucocorticoid Receptor-mediated Transrepression* (2012) (41)
Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms. (1996) (40)
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis (2017) (40)
Motor Performance in Hyperactive Children Treated with Imipramine (1988) (40)
Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells (1985) (40)
Protein synthesis and the presence or absence of a measurable G1 in cultured chinese hamster cells (1980) (40)
Road to exercise mimetics: targeting nuclear receptors in skeletal muscle. (2013) (39)
A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease (2013) (39)
Development of ecdysone-regulated lentiviral vectors. (2005) (39)
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease (2019) (38)
Molecular characterization of the glucocorticoid receptor. (1989) (38)
ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle. (2018) (38)
Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha (2012) (37)
A transcriptional basis for physiology (2004) (37)
Chromosomal localization of the human retinoid X receptors. (1994) (37)
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease (2017) (37)
Microbiology: Wealth management in the gut (2013) (37)
Farnesoid X Receptor an Emerging Target to Combat Obesity (2017) (36)
Calcitonin COOH-terminal cleavage peptide as a model for identification of novel neuropeptides predicted by recombinant DNA analysis. (1982) (35)
Oligonucleotides in heterogeneous nuclear RNA: similarity of inverted repeats and RNA from repetitious DNA sites. (1978) (35)
The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors. (2005) (34)
Metformin-Mediated Bambi Expression in Hepatic Stellate Cells Induces Prosurvival Wnt/β-Catenin Signaling (2012) (34)
Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts. (2004) (34)
42 Retinoid Receptors as Transcription Factors (1992) (33)
Acquisition of New DNA Sequences After Infection of Chicken Cells with Avian Myeloblastosis Virus (1974) (33)
Outcome and value: A perspective on rehabilitation outcomes achieved in acquired brain injury (1992) (33)
Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype. (2000) (33)
Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked (2017) (33)
Calcitonin, prolactin, and growth hormone gene expression as model systems for the characterization of neuroendocrine regulation. (1983) (32)
Extrahepatic Cancer Suppresses Nuclear Receptor–Regulated Drug Metabolism (2011) (31)
Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer (2015) (31)
Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. (2002) (30)
Peptide mapping of phosphorylated vimentin. Evidence for a site-specific alteration in mitotic cells. (1984) (30)
Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb (1989) (29)
BCL-6: a possible missing link for anti-inflammatory PPAR-δ signalling in pancreatic beta cells (2006) (29)
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes (2021) (29)
The retinoid X receptors. Modulators of multiple hormonal signaling pathways. (1994) (29)
Genetic deficiency in Pparg does not alter development of experimental prostate cancer (2003) (29)
Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy (2017) (29)
TRB 3 Links the E 3 Ubiquitin Ligase COP 1 to Lipid Metabolism (2009) (29)
ARSENITE DECREASES CYP3A4 AND RXRα IN PRIMARY HUMAN HEPATOCYTES (2005) (29)
Nuclear Receptors as Modulators of the Tumor Microenvironment (2011) (28)
Turning Up the Heat on Membrane Fluidity (2015) (28)
Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia (2017) (28)
Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla (2010) (28)
Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling. (1999) (28)
Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity. (2020) (28)
Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing (2020) (27)
Nuclear receptors and metabolism: from feast to famine (2014) (27)
NMR Spectroscopic Studies of the DNA-binding Domain of the Monomer-binding Nuclear Orphan Receptor, Human Estrogen Related Receptor-2 (1997) (26)
Methylphenidate and memory: Dissociated effects in hyperactive children (2004) (25)
Presence in Leukemic Cells of Avian Myeloblastosis Virus-Specific DNA Sequences Absent in Normal Chicken Cells (1974) (25)
Rosiglitazone activation of PPARγ suppresses fractalkine signaling (2009) (25)
E47 modulates hepatic glucocorticoid action (2019) (25)
The molecular basis of signaling by vitamin A and its metabolites. (1994) (25)
Verbal Fluency and Figural Fluency in Bright Children (1985) (25)
A neuropathic substrate for stimulant drug effects in hyperactive children. (1986) (24)
BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. (2006) (24)
Base sequence complexity of 35S avian myeloblastosis virus RNA determined by molecular hybridization kinetics. (1975) (24)
Neural basis of opioid-induced respiratory depression and its rescue (2020) (23)
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts (2020) (23)
ERRγ Preserves Brown Fat Innate Thermogenic Activity. (2018) (23)
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. (2020) (23)
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes (2021) (22)
Nuclear receptors and AMPK: can exercise mimetics cure diabetes? (2016) (22)
Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity (2018) (22)
Retinoid receptors. (1993) (22)
Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene. (2014) (22)
MMPI Characteristics of Borderline Personality Inpatients (1984) (21)
Identification of Three Novel Natural Product Compounds that Activate PXR and CAR and Inhibit Inflammation (2013) (21)
Identification of two regions of the human glucocorticoid receptor hormone binding domain that block activation. (1989) (21)
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia (2017) (21)
ERRATUM: PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 (2004) (20)
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas (2020) (20)
The PML domain of PML–RARα blocks senescence to promote leukemia (2014) (20)
Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells. (1998) (19)
Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease? (2013) (19)
Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with β‐Catenin and Chromatin Remodelling (2016) (19)
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. 1982. (1992) (19)
DSF nuclear receptor acts as a repressor in culture and in vivo. (2002) (18)
Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes. (2005) (18)
Metabolism: Tick, tock, a β-cell clock (2010) (18)
Nuclear receptors and AMPK: resetting metabolism. (2011) (18)
Psychostimulant pharmacology in traumatic brain injury (1987) (18)
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3 (2020) (18)
Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. (2003) (18)
FGF1 and insulin control lipolysis by convergent pathways. (2022) (17)
Bile Acid Analog Intercepts Liver Fibrosis (2016) (17)
Peroxisome Proliferator-Activated Receptor-Deficient Heterozygous Mice Develop an Exacerbated Neural Antigen-Induced Th1 Response and Experimental Allergic Encephalomyelitis. (2004) (17)
Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion (2016) (17)
Erratum: The commonly used antimicrobial additive triclosan is a liver tumor promoter (Proc Natl Acad Sci USA (2014) 111 (17200-17205) DOI: 10.1073/pnas.1419119111) (2015) (17)
Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein. (1995) (16)
Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells. (1974) (16)
Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research (2014) (16)
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. (2022) (16)
NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix. (1994) (16)
Carbamazepine: a neuropsychological and psychiatric profile. (1985) (15)
Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. (2012) (15)
Mouse embryos lacking RXR α are resistant to retinoic-acid-induced limb defects (1995) (15)
Biological function and mode of action of nuclear xenobiotic receptors (2003) (15)
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity (2019) (15)
Rescue of a primary myelofibrosis model by retinoid-antagonist therapy (2013) (15)
Human steroid receptors and erbA proto-oncogene products: members of a new superfamily of enhancer binding proteins. (1986) (14)
Functional antagonism between oncoprotein c-Jun and steroid hormone receptors. (1991) (14)
Targeting the pregnane X receptor in liver injury (2012) (14)
ERRγ Regulates Cardiac, Gastric, and Renal Potassium Homeostasis. (2009) (14)
β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity (2021) (14)
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. (2015) (14)
Genes encoding mammalian neuroendocrine peptides: strategies toward their identification and analysis. (1986) (14)
Co-repressor Release but Not Ligand Binding Is a Prerequisite for Transcription Activation by Human Retinoid Acid Receptor α Ligand-binding Domain* (2002) (14)
Postacute neurorehabilitation: roles and responsibilities within a national information system. (1997) (14)
The transcriptional basis of steroid physiology. (1998) (14)
Metabolic Regulation by Nuclear Receptors (2015) (14)
NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection (2017) (14)
Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms. (2005) (14)
Human steroid receptors and erb-A gene products form a superfamily of enhancer-binding proteins. (1987) (13)
The synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA. (1979) (13)
A Nuclear Strike against Listeria— The Evolving Life of LXR (2004) (12)
Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells (2014) (12)
PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. (2010) (12)
The molecular genetics of retinoic acid receptors: cardiovascular and limb development. (1996) (12)
The Drosophila nuclear receptors: new insight into the actions of nuclear receptors in development. (1992) (12)
Vimentin-dependent utilization of LDL-cholesterol in human adrenal tumor cells is not associated with the level of expression of apoE, sterol carrier protein-2, or caveolin. (1999) (12)
β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin (2019) (12)
Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis (2018) (12)
Molecular events in developmental regulation of neuroendocrine genes: characterization of the novel neuropeptide CGRP. (1983) (12)
Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells. (2011) (11)
Steroid hormone receptor homologs in development. (1989) (11)
Cooperative and positional independent trans-activation domains of the human glucocorticoid receptor. (1988) (11)
Liver Cancer Checks in When Bile Acid Clocks Out. (2016) (11)
Preclinical development of ARRY-142886, a potent and selective MEK inhibitor (2004) (10)
Daily running enhances molecular and physiological circadian rhythms in skeletal muscle (2022) (10)
The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson’s disease (2015) (10)
The Influence of Outcome Studies on Rehabilitation Policy (1997) (10)
Unexpected heterogeneity of PML/RAR alpha fused mRNA detected by nested polymerase chain reaction in acute promyelocytic leukemia. (1993) (10)
Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice (2021) (9)
Carbamazepine‐induced Tics (1984) (9)
Predicting Outcome Following Traumatic Brain Injury (1998) (9)
Discovery and Optimization of Non‐steroidal FXR Agonists from Natural Product‐Like Libraries. (2003) (9)
Creation of transgenic animals to study development and as models for human disease. (1985) (9)
Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity (2017) (9)
Outcome validation in post-acute rehabilitation: trends and correlates in treatment and outcome. (1992) (9)
The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection (2021) (8)
Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease (2018) (8)
The Medical Treatment of Autistic People (1987) (8)
On the Consistency of the MMPI in Borderline Personality Disorder (1986) (8)
Rational application of macrophage-specific LXR agonists avoids the pitfalls of SREBP-induced lipogenesis (2018) (8)
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity (2021) (8)
RNA processing regulation of neuroendorcrine gene expression. (1982) (7)
Mild Traumatic Brain Injury (1992) (7)
Opsoclonus in a confirmed case of St. Louis encephalitis. (1982) (7)
Repression of retinoic acid-induced transactivation by embryonal LTR binding protein. (1994) (7)
Blood level measurement of psychoactive drugs in pediatric psychiatry. (1984) (7)
Transgenic expression of PML / RARa impairs myelopoiesis ( acute promyelocytic leukemia / transgene / all-trans retinoic acid ) (7)
Erratum: Pgc1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss (Cell Metabolism (2010) 11 (503-516)) (2010) (7)
Integrating outcomes, value, and quality. An outcome validation system for post-acute rehabilitation programs. (1991) (7)
A novel pathway for retinoic acid-induced differentiation of F9 cells that is distinct from receptor-mediatedTrans-activation (1994) (6)
The quest to burn fat, effortlessly and safely (2016) (6)
Bisphenol A derivatives act as novel coactivator-binding inhibitors for estrogen receptor β (2021) (6)
BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4 (2021) (6)
Inducible and developmental control of neuroendocrine genes. (1985) (6)
Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala (2020) (6)
The definition of transcription units for mRNA. (1978) (6)
Corepressor SMRT binds the BTB y POZ repressing domain of the LAZ 3 y BCL 6 oncoprotein (1997) (6)
Establishing Orphan Nuclear Receptors PXR and CAR as Xenobiotic Receptors (2008) (6)
A SU2C catalyst randomized phase II trial of pembrolizumab with or without paricalcitol in patients with stage IV pancreatic cancer who have been placed in best possible response. (2018) (6)
Rat growth hormone gene: intervening sequences separate the mRNA regions. (1979) (6)
Polypeptide Hormone Regulation of Gene Expression (2001) (6)
Ligand-Dependent Corepressor (LCoR) Is a Rexinoid-Inhibited Peroxisome Proliferator-Activated Receptor γ–Retinoid X Receptor α Coactivator (2018) (6)
Genetic Analysis of the Retinoid Signal a (1996) (6)
Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer (2021) (5)
Alternative RNA processing events as a critical developmental regulatory strategy in neuroendocrine gene expression. (1984) (5)
PS21 - 100. A PPAR -FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis (2012) (5)
Alternate selective reminding forms for children (1986) (5)
PPARδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection (2016) (5)
Vitamin D receptor agonist paricalcitol plus gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer. (2020) (4)
Hemispheric Asymmetry and Recategorized Wisc—R Patterns in Learning-Disabled and Nondisabled Children (1992) (4)
Adipose tissue heparan sulfate proteoglycans – critical regulators of adipocyte metabolism and glucose homeostasis (2020) (4)
Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer (2019) (4)
Corrigendum: Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells (2014) (4)
PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis. (2022) (4)
Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer (2015) (4)
Commentary and an illustration on the use of outcome data in life care planning for persons with acquired neurological injuries. (1996) (4)
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring (2019) (3)
Studies on characterization of the integration sites of avian RNA tumor virus-specific DNA. (1975) (3)
Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer (2016) (3)
Shared Mechanisms between Cardiovascular Disease and NAFLD (2022) (3)
Metabolism: Tick, tock, a high-fat clock (2014) (3)
Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-delta gene (2019) (3)
Peroxisome-Proliferator-Activated Receptor Activates Fat Metabolism to Prevent (2003) (3)
Disease tolerance mediated by commensal E . coli via inflammasome and IGF-1 signaling (2016) (3)
Nuclear receptors and AMPK: can exercise mimetics cure diabetes (2013) (3)
The v‐erbA oncogene is a thyroid hormone receptor antagonist (1989) (3)
Journal of Molecular Endocrinology 25th anniversary special issue. (2013) (3)
An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. (2016) (2)
Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses (2020) (2)
4981784 Retinoic acid receptor method (1991) (2)
Obesity Potentiates TH2 Immunopathology via Dysregulation of PPARγ (2019) (2)
Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity (2018) (2)
Abstract IA9: Vitamin D: Shining light on pancreatic cancer (2015) (2)
Ligand-Dependent Corepressor (LCoR) Is a Rexinoid-Inhibited Peroxisome Proliferator-Activated Receptor (cid:2) –Retinoid X Receptor (cid:3) Coactivator (2018) (2)
Hormonal regulation of gene expression: regulation of growth hormone gene transcription by growth hormone releasing factor. (1985) (2)
Retinoic Acid in Myeloid Differentiation and Acute Promyelocytic Leukemia (APL) (2003) (2)
SRF’ing Around the Clock (2013) (2)
ARSENITE DECREASES CYP 3 A 4 AND RXR IN PRIMARY HUMAN HEPATOCYTES (2005) (2)
Retinoid receptors in development and disease. (1997) (2)
FXR mediates ILC-intrinsic responses to intestinal inflammation. (2022) (2)
Autocrine FGF1 signaling promotes glucose uptake in adipocytes (2022) (2)
Chronicle of a discovery: the retinoic acid receptor. (2022) (2)
Interorgan crosstalk in pancreatic islet function and pathology (2022) (2)
Functional roles of Sox2 for the molecular regulation of TLX/NR2E1 in adult neural stem/progenitor cells (2011) (1)
Hormone-Dependent Transcriptional Activation by Thyroid Hormone Receptors: Functional Homology with Steroid Hormone Receptors (1989) (1)
17 – Molecular Mechanisms of Epidermal Growth Factor Regulation of Prolactin Gene Transcription (1987) (1)
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH (2020) (1)
Homodimerization of Retinoic Acid Receptor alpha through its Fusion Partners Underlies Pathogenesis of Acute Promyelocytic Leukemia. (2004) (1)
Metabolism and cancer in La Jolla. (2010) (1)
Circadian Clock Protein CRY Controls B-Cell Intrinsic Tolerance (2015) (1)
ERR g Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1 a / b -De ﬁ cient Muscle (2018) (1)
Teachers ’ Participation in Research Programs Improves Their Students ’ Achievement in Science (2015) (1)
Circadian benefits of exercise training reflect metabolic and structural flexibility (2020) (1)
A Neural Thyroid Hormone Receptor Gene (1989) (1)
Reply to "PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation" (2016) (1)
Neuron-specific alternative RNA processing in neuroendocrine gene expression. (1987) (1)
A broad view of brain injury rehabilitation. Community-integrated network of excellence. (1991) (1)
Managing forests for white-tailed eagles. (2011) (1)
Abstract 396: The bile acid receptor FXR suppress colitis-induced colon cancer (2020) (1)
Retrofitting fat metabolism. (2009) (1)
Let's Raise a Glass to Sydney: In Memoriam (1927-2019) (2019) (1)
Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia (2017) (1)
A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1)
Staying the distance: avoiding the proteasomal trap. (2008) (1)
Visible light reduces C. elegans longevity (2018) (1)
Proton pump inhibitor use status does not modify the microbiome signature for cirrhosis. (2021) (1)
A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity (2022) (1)
Homogeneity and complexity of avian oncornavirus proviral DNA determined by molecular hybridization (1977) (1)
Estrogen-Related Receptor γ maintains pancreatic acinar cell function and identity by regulating cellular metabolism. (2022) (1)
Abstract 3036: Real-time genomic characterization of metastatic pancreatic cancer to enable precision medicine (2017) (1)
Ultrason et lumiere (1992) (1)
112. PML-RAR. A fusion protein in human acute promyelocytic leukemia (1992) (0)
By protoonkogenischen protein complex AP-1 controlled procedures (1991) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 1 (2017) (0)
PIDDosome-SCAP Crosstalk Controls Diet Dependent Transition from Simple Steatosis to Steatohepatitis (2021) (0)
Unified neural pathways that gate affective pain and 1 multisensory innate threat signals to the amygdala 2 3 4 (2020) (0)
Immune-evasive human islet-like organoids ameliorate diabetes (2020) (0)
E47 modulates hepatic glucocorticoid action (2019) (0)
Global chemical effects of the microbiome include new bile-acid conjugations (2020) (0)
Crystal structure of PPAR delta complexed with GW2331 (2005) (0)
REV-ERBα negatively regulates the Th17 mediated immune response (IRM15P.603) (2015) (0)
NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection (2017) (0)
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3 (2020) (0)
Abstract SY04-04: Vitamin D receptor stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy (2014) (0)
678: GUT METAGENOME-DERIVED SIGNATURE PREDICTS HEPATIC DECOMPENSATION AND MORTALITY IN NASH-RELATED CIRRHOSIS (2022) (0)
Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes (2021) (0)
The Endocrine Society 1999 Annual Awards (1999) (0)
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. (2023) (0)
Quantitative and qualitative differences in DNA complementary to avian myeloblastosis virus between normal and leukemic chicken cells. (1975) (0)
S116R Phosphorylation Site Mutation in Human FGF-1 Differentially Affects Mitogenic and Glucose Lowering Activities (2016) (0)
United States Patent ( 19 ) Evans et al . ( 54 ) METHOD OF OBTAINING GENE PRODUCT THROUGH THE GENERATION OF TRANSGENIC ANIMALS (2017) (0)
PHITE: Precision High Intensity Training Through Epigenetics (2020) (0)
Effects of peroxisome prolife 6 on placentation, adiposity, (2016) (0)
Retinoic Acid Receptor Gamma (1990) (0)
CRY 1 / 2 Selectively Repre ss PPAR d and Limit Exercise Capacity Graphical Abstract Highlights (2017) (0)
Abstract A115: Use of angiotensin system inhibitors is associated with immune activation and longer survival in pancreatic ductal adenocarcinoma patients (2019) (0)
Nuclear Receptor Coactivators Co-ordinate Metabolic Responses to Hormonal and Environmental Stimuli (2008) (0)
Preface: Nuclear Receptors: Past, Present, and Future (2009) (0)
Human PPARdelta ligand-binding domain in complexed with GW501516 (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 6 (2017) (0)
Abstract 509: Critical Role of the Transcriptional Repressor BCL-6 in Bone Marrow-Derived Inflammation and Atherosclerosis (2008) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 13 (2017) (0)
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia (vol 114, pg E1432, 2017) (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 12 (2017) (0)
Receptors, as well as the identification, characterization, preparation and use of such (1991) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 4 (2017) (0)
Table S3. Genes Regulated by PPARγ in Wild-Type and Stat6−/− Mouse Macrophages (2010) (0)
An interview with Ronald M. Evans, Ph.D. Investigator, the Salk Institute for Biological Studies. (2003) (0)
RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA (1997) (0)
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease (2019) (0)
Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes (2021) (0)
ERRgamma mediated metabolic maturation toward functional beta cells (2016) (0)
Abstract IA04: Stromal regulation of pancreatic cancer epigenome and metabolome (2016) (0)
FUTURE ANNUAL MEETINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (2017) (0)
In Memoriam: Kazuhiko Umesono (1958–1999) (2000) (0)
The GR at inflammatory crossroads (2012) (0)
Negative Regulation of Enhancer‐Associated RNA in Macrophages (2012) (0)
11 – Retinoid and Thyroid Hormone Receptors (1991) (0)
Table S1. Genes Regulated in Human Macrophages by PPARγ (2010) (0)
Abstract B10: Function and therapeutic implications of p53 in the stroma of pancreatic cancer (2015) (0)
The functional and pharmacological ecdysone receptor is the product of ECR and ultraspiracle (1994) (0)
Metabolic Messengers: fibroblast growth factor 1 (2022) (0)
Trans-activation bythyroid hormone receptors: Functional parallels withsteroid hormonereceptors (1989) (0)
The Drosophila nuclear receptors: new insight into the actions of nuclear receptors in development (1992) (0)
Corralling Pancreatic Cancer through Epigenetic Reprogramming (2018) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 8 (2017) (0)
PO-096 Defining the role of Myc in the pancreatic cancer super enhancer network (2018) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 5 (2017) (0)
Abstract A42: Paracrine regulation of the pancreatic cancer epigenome (2015) (0)
Alternative RNA processing events gene-related peptide gene expressi (neuroendocrine/pituitary/RNA processing/hormone precursor) (2016) (0)
Identification of Three Novel Natural Product Compounds that Activate PXR and CAR and Inhibit Inflammation (2013) (0)
The Acute Promyelocytic Leukemia-Oncoprotein PML-Raralpha Blocks Senescence and Disrupts The Atrx/Daxx Chromatin Remodeling Complex To Promote Leukemia (2013) (0)
Timed use of cardiac glycoside protects the heart (2022) (0)
Oleic acid regulates hippocampal neurogenesis as a TLX ligand (2022) (0)
Table S2. Genes Regulated by IL-4 in Pparγ+/−LysCre and Ppargfl/−LysCre Mouse Macrophages (2010) (0)
The peroxisome proliferator-; an integrator of transcriptior nuclear receptor signaling (2016) (0)
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring (2021) (0)
Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR (2002) (0)
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 3 (2017) (0)
Positive evidence for a role of the PML pathway in leukemogenesis of acute promyelocytic leukemia (2010) (0)
Wylie Walker Vale Jr (1941–2012) (2012) (0)
Abstract B24: p53 mediates reprograming of cancer-associated fibroblasts in pancreatic cancer (2016) (0)
Author response: Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration (2016) (0)
Target acquisition and acute promyelocytic leukemia. (1999) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 9 (2017) (0)
ESTROGEN RELATED RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH DNA (2003) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 14 (2017) (0)
1H, 13C, and 15N Chemical shifts for hERR2 Protein, 1H chemical shifts for DNA (2010) (0)
Laser microbeam abalation of GFP-labeled nuclear organelles in a living cell. (1997) (0)
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling ( heterodimer / hormone response element / orphan receptor ) (0)
Abstract 957: Use of angiotensin system inhibitors is associated with longer overall survival in pancreatic ductal adenocarcinoma patients who underwent pancreatectomy (2017) (0)
Germination of the seeds of the white pine (0)
Harvesting Timber Crops in the National Forests of the East and South (2018) (0)
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring (2021) (0)
Su494 RESTORATION OF FXR SIGNALING IN INNATE LYMPHOID CELLS SUPPRESSES INTESTINAL INFLAMMATION (2021) (0)
progressmuscle adaptation to exercise: a century of (2015) (0)
What can we do about long-term sequelae of traumatic brain injury? (2001) (0)
The Life Coach Model of Community Re-entry (2021) (0)
Processes mediated by the protooncogene protein complex AP-1 (1991) (0)
Abstract B03: Control of pancreatic cancer metabolism and histone acetylation by the tumor microenvironment (2016) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 16 (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 2 (2017) (0)
Receptor gamma-retinoic acid. (1990) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 10 (2017) (0)
The autophagy initiating kinase ULK1 is required for pancreatic cancer cell growth and survival (2021) (0)
113. Reverse transcription polymerase chain reaction (RT-PCR) for the rearranged retinoic acid receptor-α (RAR-α) predicts response of acute promyelocytic leukemia (APL) to retinoic acid (RA) therapy and detects minimal residual disease (1992) (0)
30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Short reflections on the discovery of the mineralocorticoid receptor. (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 11 (2017) (0)
Retinoic acid receptor-ligand composition and method for identification. (1988) (0)
Abstract 1228: Peroxisome Proliferator-Activated Receptor {gamma} regulating MnSOD Expression is Essential to Maintain Myocardial Redox Homeostasis (2006) (0)
Pharmacological and genetic manipulation of peroxisome proliferator-activated receptors in the MPTP model of Parkinson’s disease (2013) (0)
Abstract A29: Bicompartmental regulation of disease-related gene networks by histone deacetylase inhibition curbs pancreatic cancer progression (2019) (0)
The pharmaco-genetics of congenital cardiac defects in retinoic acid receptor deficient mouse embryos (1996) (0)
Calcitonin and Calcitonin-Related Peptide Genes (1987) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 7 (2017) (0)
Su1594 GUT MICROBIOME METAGENOMICS REVEALS FUNGAL MYCOBIOME ALTERATION IN NAFLD CIRRHOSIS WITH VALIDATION IN A GEOGRAPHICALLY INDEPENDENT COHORT (2020) (0)
Corepressor SMRT binds the BTByPOZ repressing domain of the LAZ3yBCL6 oncoprotein (transcriptional repressionydiffuse large cell lymphomasyyeast two-hybrid screen) (1997) (0)
Abstract IA13: Stromal regulation and therapeutic targeting of the pancreatic cancer epigenome (2016) (0)
FARNESOID ACTIVATED RECEPTOR POLYPEPTIDES , AND NUCLEICACID ENCODING THE SAME 75 Inventors : (2017) (0)
Human PPARdelta ligand-binding domain in complexed with specific agonist 15 (2017) (0)
UNIVERSITY OF CALIFORNIA, SAN DIEGO Fat-Resident Regulatory T Cells Drive Age-Associated Insulin Resistance A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Biomedical Sciences by (2016) (0)
Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts (2019) (0)
Abstract RAOS15-03: Pancreatic tumor stroma as a therapeutic target (2015) (0)
University of Groningen Fibroblast Growth Factor Signaling in Metabolic Regulation (2016) (0)
Functions of PPAR Gamma in Macrophages and Atherosclerosis (2002) (0)
Abstract 5065: Harnessing epigenetic reprogramming by histone deacetylase inhibitor MS275 for pancreatic cancer therapy (2017) (0)
Nuclear receptors: past, present, and future. Preface. (2009) (0)
Elements beta retinoic acid response, and test compositions. (1990) (0)
The Contributions of the Steroid Receptor Superfamily to Development, Physiology and Medicine (1989) (0)
Correction for Chen et al., Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia (2017) (0)
Intestinal FXR: A New Therapeutic Target for Nonalcoholic Fatty Liver Disease (2015) (0)

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