Ronald T. Raines
#25,706
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American biochemist
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Ronald T. Rainesbiology Degrees
Biology
#1951
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#3149
Historical Rank
#910
USA Rank
Biochemistry
#288
World Rank
#353
Historical Rank
#124
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Biology
Ronald T. Raines's Degrees
- Bachelors Chemistry University of California, Davis
Why Is Ronald T. Raines Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ronald T. Raines is an American chemical biologist. He is the Roger and Georges Firmenich Professor of Natural Products Chemistry at the Massachusetts Institute of Technology. He is known for using ideas and methods of physical organic chemistry to solve important problems in biology.
Ronald T. Raines's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Collagen structure and stability. (2009) (2587)
- Simple chemical transformation of lignocellulosic biomass into furans for fuels and chemicals. (2009) (1314)
- Bright ideas for chemical biology. (2008) (979)
- Hydrolytic stability of hydrazones and oximes. (2008) (643)
- Collagen‐based biomaterials for wound healing (2014) (610)
- Fermentable sugars by chemical hydrolysis of biomass (2010) (458)
- Ribonuclease A. (1998) (419)
- Staudinger ligation: a peptide from a thioester and azide. (2000) (412)
- Code for collagen's stability deciphered (1998) (396)
- Pathway for polyarginine entry into mammalian cells. (2004) (354)
- Conformational stability of collagen relies on a stereoelectronic effect. (2001) (331)
- Prolyl 4-hydroxylase (2010) (326)
- Bright Building Blocks for Chemical Biology (2014) (325)
- Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles (2014) (278)
- n→π* Interactions in Proteins (2010) (277)
- Advances in Bioconjugation. (2010) (272)
- Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments (1998) (260)
- Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations. (2002) (256)
- RNS2: a senescence-associated RNase of Arabidopsis that diverged from the S-RNases before speciation. (1993) (252)
- The CXXC motif: a rheostat in the active site. (1997) (247)
- Self-assembly of synthetic collagen triple helices. (2006) (246)
- Synthesis of furfural from xylose and xylan. (2010) (240)
- The n→π* Interaction (2017) (233)
- Nature of Amide Carbonyl−Carbonyl Interactions in Proteins (2009) (224)
- The Essential Function of Protein-disulfide Isomerase Is to Unscramble Non-native Disulfide Bonds (*) (1995) (216)
- Selenocysteine in native chemical ligation and expressed protein ligation. (2001) (210)
- Ribonuclease A variants with potent cytotoxic activity. (1998) (208)
- An electronic effect on protein structure (2003) (208)
- A hyperstable collagen mimic. (1999) (202)
- Ribonuclease S‐peptide as a carrier in fusion proteins (1993) (192)
- Triosephosphate isomerase catalysis is diffusion controlled (1988) (191)
- Chemical synthesis of proteins. (2005) (189)
- Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. (2007) (186)
- Boronate-Mediated Biologic Delivery (2012) (183)
- Biomass to Furanics: Renewable Routes to Chemicals and Fuels (2015) (182)
- Site-specific protein immobilization by Staudinger ligation. (2003) (182)
- High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide. (2001) (178)
- Insights on the conformational stability of collagen. (2002) (176)
- Cancer chemotherapy--ribonucleases to the rescue. (2001) (173)
- Fluorogenic label for biomolecular imaging. (2006) (173)
- Mechanistic insights on the conversion of sugars into 5-hydroxymethylfurfural (2010) (171)
- Translocation of a beta-peptide across cell membranes. (2002) (170)
- Hypersensitive substrate for ribonucleases. (1999) (169)
- The CXXC motif: imperatives for the formation of native disulfide bonds in the cell. (1996) (169)
- An Evaluation of Peptide‐Bond Isosteres (2011) (166)
- Microscopic pKa values of Escherichia coli thioredoxin. (1997) (166)
- Ribonuclease inhibitor: structure and function. (2005) (164)
- Inductive Effects on the Energetics of Prolyl Peptide Bond Isomerization: Implications for Collagen Folding and Stability. (1996) (163)
- Triosephosphate isomerase catalysis is diffusion controlled. Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR. (1988) (155)
- Stereoelectronic effects on polyproline conformation (2006) (153)
- Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism. (2011) (151)
- n→π* Interactions of Amides and Thioamides: Implications for Protein Stability (2013) (147)
- Contribution of disulfide bonds to the conformational stability and catalytic activity of ribonuclease A. (2000) (137)
- Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers. (2003) (137)
- Stereoelectronic and steric effects in side chains preorganize a protein main chain (2009) (132)
- Tuning the pK(a) of fluorescein to optimize binding assays. (2007) (130)
- Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. (2005) (130)
- Reaction mechanism and kinetics of the traceless Staudinger ligation. (2006) (129)
- Effect of 3-hydroxyproline residues on collagen stability. (2003) (122)
- Ribonuclease inhibitor as an intracellular sentry. (2003) (120)
- Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. (1995) (116)
- Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association. (2005) (114)
- Protein assembly by orthogonal chemical ligation methods. (2003) (112)
- Value of general Acid-base catalysis to ribonuclease a. (1994) (111)
- Polyarginine as a multifunctional fusion tag (2005) (111)
- Evolutionary optimization of the catalytic effectiveness of an enzyme. (1989) (109)
- Amide-Amide and Amide-Water Hydrogen Bonds: Implications for Protein Folding and Stability. (1994) (105)
- n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. (2010) (105)
- Energetics of catalysis by ribonucleases: fate of the 2',3'-cyclic phosphodiester intermediate. (1994) (104)
- Native disulfide bond formation in proteins. (2000) (104)
- Inductive effects on the structure of proline residues. (2009) (103)
- General acid/base catalysis in the active site of Escherichia coli thioredoxin. (1997) (103)
- Energetics of an n --> pi interaction that impacts protein structure. (2006) (103)
- Reciprocity of steric and stereoelectronic effects in the collagen triple helix. (2006) (103)
- Interplay of hydrogen bonds and n→π* interactions in proteins. (2013) (102)
- Mechanism of Ribonuclease Cytotoxicity (*) (1995) (99)
- Diazo Compounds: Versatile Tools for Chemical Biology. (2016) (98)
- Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. (2008) (97)
- Olefin metathesis for chemical biology. (2008) (95)
- Structural determinants of enzymatic processivity. (1994) (95)
- Imaging the binding ability of proteins immobilized on surfaces with different orientations by using liquid crystals. (2004) (95)
- Protein Prosthesis: A Semisynthetic Enzyme with a β-Peptide Reverse Turn (2002) (95)
- Latent fluorophore based on the trimethyl lock. (2005) (91)
- Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases. (2004) (91)
- Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging. (2018) (91)
- Ribonuclease a: revealing structure-function relationships with semisynthesis. (1995) (90)
- A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid (2012) (90)
- Reaction energetics of a mutant triosephosphate isomerase in which the active-site glutamate has been changed to aspartate. (1986) (89)
- The CXC motif: a functional mimic of protein disulfide isomerase. (2003) (87)
- Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway (2003) (86)
- Trimethyl lock: A trigger for molecular release in chemistry, biology, and pharmacology. (2012) (85)
- α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. (2015) (84)
- Mechanistic studies on the pyridoxal phosphate enzyme 1-aminocyclopropane-1-carboxylate deaminase from Pseudomonas sp. (1981) (82)
- Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation. (2007) (81)
- Internalization of cationic peptides: the road less (or more?) traveled (2006) (81)
- Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase. (1987) (81)
- Cytosolic Delivery of Proteins by Bioreversible Esterification. (2017) (80)
- Active site of triosephosphate isomerase: in vitro mutagenesis and characterization of an altered enzyme. (1985) (80)
- Olefin metathesis in homogeneous aqueous media catalyzed by conventional ruthenium catalysts. (2007) (79)
- Intimate interactions with carbonyl groups: dipole-dipole or n→π*? (2013) (79)
- Endowing Human Pancreatic Ribonuclease with Toxicity for Cancer Cells* (2001) (78)
- A phosphine-mediated conversion of azides into diazo compounds. (2009) (77)
- Conformational Stability Is a Determinant of Ribonuclease A Cytotoxicity* (2000) (77)
- Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans. (2000) (77)
- The S.Tag fusion system for protein purification. (2000) (77)
- A small-molecule catalyst of protein folding in vitro and in vivo. (1999) (75)
- Catalysis of imido group hydrolysis in a maleimide conjugate. (2007) (74)
- Semisynthesis and characterization of mammalian thioredoxin reductase. (2006) (74)
- Chemoselectivity in Chemical Biology: Acyl Transfer Reactions with Sulfur and Selenium (2011) (73)
- Synthesis and utility of fluorogenic acetoxymethyl ethers. (2011) (73)
- A prevalent intraresidue hydrogen bond stabilizes proteins (2016) (72)
- Conversion of biomass to sugars via ionic liquid hydrolysis: process synthesis and economic evaluation (2012) (71)
- Quantitative analysis of the effect of salt concentration on enzymatic catalysis. (2001) (70)
- Solvent Effects on the Energetics of Prolyl Peptide Bond Isomerization. (1992) (70)
- Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues. (2008) (69)
- Secondary Forces in Protein Folding. (2019) (69)
- Peptide bond isosteres: ester or (E)-alkene in the backbone of the collagen triple helix. (2005) (68)
- Staudinger Ligation of α-Azido Acids Retains Stereochemistry (2002) (68)
- Dimer formation by a “monomeric” protein (2000) (67)
- Arginine grafting to endow cell permeability. (2007) (67)
- Structural Basis for the Biological Activities of Bovine Seminal Ribonuclease (*) (1995) (67)
- Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities. (1995) (67)
- Organocatalytic Conversion of Cellulose into a Platform Chemical. (2013) (66)
- Signatures of n→π* interactions in proteins (2014) (65)
- General method for site-specific protein immobilization by Staudinger ligation. (2007) (65)
- Analysis of Receptor-Ligand Interactions. (1995) (65)
- Catalysis of protein folding by protein disulfide isomerase and small-molecule mimics. (2003) (65)
- Conversion of fructose into 5-(hydroxymethyl)furfural in sulfolane. (2011) (64)
- 4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix. (2008) (63)
- Salicylaldimine Ruthenium Alkylidene Complexes: Metathesis Catalysts Tuned for Protic Solvents. (2007) (63)
- Limits to Catalysis by Ribonuclease A. (1995) (62)
- Coulombic effects of remote subsites on the active site of ribonuclease A. (1998) (61)
- Genetic selection for dissociative inhibitors of designated protein–protein interactions (2000) (60)
- The aberrance of the 4S diastereomer of 4-hydroxyproline. (2010) (60)
- Peptide tessellation yields micron-scale collagen triple helices (2016) (58)
- An n→π* interaction in aspirin: implications for structure and reactivity. (2011) (58)
- Coulombic forces in protein-RNA interactions: binding and cleavage by ribonuclease A and variants at Lys7, Arg10, and Lys66. (1998) (58)
- Signature of n→π* interactions in α‐helices (2011) (58)
- His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes. (1998) (57)
- Potent Inhibition of Ribonuclease A by Oligo(vinylsulfonic Acid)* (2003) (57)
- Ribonucleases as novel chemotherapeutics : the ranpirnase example. (2008) (56)
- Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A. (2005) (56)
- Self-Assembled Collagen-like Peptide Fibers as Templates for Metallic Nanowires. (2008) (55)
- Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides. (2011) (55)
- A New Remote Subsite in Ribonuclease A* (1998) (53)
- Cytotoxicity of bovine seminal ribonuclease: monomer versus dimer. (2005) (52)
- Protein prosthesis: a nonnatural residue accelerates folding and increases stability. (2003) (52)
- A key n→π* Interaction in N-acyl homoserine lactones. (2014) (51)
- Adjacent cysteine residues as a redox switch. (2001) (51)
- The ribonucleolytic activity of angiogenin. (2002) (51)
- Activation of the Prolyl Hydroxylase Oxygen-sensor Results in Induction of GLUT1, Heme Oxygenase-1, and Nitric-oxide Synthase Proteins and Confers Protection from Metabolic Inhibition to Cardiomyocytes* (2003) (51)
- Diazo Groups Endure Metabolism and Enable Chemoselectivity in Cellulo (2015) (51)
- Staudinger ligation of peptides at non-glycyl residues. (2006) (50)
- Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands. (2007) (50)
- A Ribonuclease A Variant with Low Catalytic Activity but High Cytotoxicity* (2000) (50)
- Diazo Compounds as Highly Tunable Reactants in 1,3-Dipolar Cycloaddition Reactions with Cycloalkynes(). (2012) (49)
- Onconase cytotoxicity relies on the distribution of its positive charge (2009) (49)
- Optimized diazo scaffold for protein esterification. (2015) (49)
- A residue to residue hydrogen bond mediates the nucleotide specificity of ribonuclease A. (1995) (48)
- Cytotoxic ribonucleases: the dichotomy of Coulombic forces. (2007) (48)
- Substrate binding and turnover by the highly specific I-PpoI endonuclease. (1996) (48)
- n→π* interactions in poly(lactic acid) suggest a role in protein folding. (2013) (48)
- Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity. (2003) (47)
- Thioamides in the collagen triple helix. (2015) (47)
- Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability. (2004) (47)
- A stereoelectronic effect in prebiotic nucleotide synthesis. (2010) (46)
- Tunable, post-translational hydroxylation of collagen Domains in Escherichia coli. (2011) (46)
- Origin of the stability conferred upon collagen by fluorination. (2009) (46)
- His ... Asp catalytic dyad of ribonuclease A: histidine pKa values in the wild-type, D121N, and D121A enzymes. (1999) (46)
- A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease (2000) (45)
- Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding. (2001) (45)
- Latent Blue and Red Fluorophores Based on the Trimethyl Lock (2006) (44)
- X-ray Structure of Two Crystalline Forms of aStreptomycete Ribonuclease with Cytotoxic Activity* (2002) (44)
- Interaction of nucleic acids with the glycocalyx. (2012) (44)
- A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity. (2017) (44)
- Creation of a zymogen (2003) (43)
- Glycosylation of onconase increases its conformational stability and toxicity for cancer cells. (2004) (43)
- Ribonucleases as Novel Chemotherapeutics (2012) (43)
- Ribonuclease inhibitor regulates neovascularization by human angiogenin. (2009) (42)
- 1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides. (2016) (42)
- Comprehensive comparison of the cytotoxic activities of onconase and bovine seminal ribonuclease. (2003) (41)
- Reconstitution of a defunct glycolytic pathway via recruitment of ambiguous sugar kinases. (2005) (41)
- Diazo compounds for the bioreversible esterification of proteins (2014) (41)
- Cellular uptake of ribonuclease A relies on anionic glycans. (2010) (41)
- Collagen Prolyl 4-Hydroxylase as a Therapeutic Target. (2018) (41)
- Fluorescence polarization assay to quantify protein-protein interactions. (2004) (40)
- Green fluorescent protein as a signal for protein–protein interactions (1997) (40)
- Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid. (2018) (40)
- A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation (2014) (40)
- Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization. (2006) (40)
- Catalysis by ribonuclease A is limited by the rate of substrate association. (2003) (39)
- Decavanadate inhibits catalysis by ribonuclease A. (2000) (39)
- Replacing a Surface Loop Endows Ribonuclease A with Angiogenic Activity (*) (1995) (39)
- Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation. (2013) (38)
- n→π* Interactions Engender Chirality in Carbonyl Groups (2014) (38)
- MECHANISM-BASED INACTIVATION OF RIBONUCLEASE A (1995) (38)
- Structural basis for catalysis by onconase. (2008) (38)
- Functional evolution of ribonuclease inhibitor: insights from birds and reptiles. (2014) (38)
- Variants of ribonuclease inhibitor that resist oxidation (2008) (37)
- Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTs. (2017) (37)
- KFERQ Sequence in Ribonuclease A-mediated Cytotoxicity* (2002) (36)
- Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor (2018) (36)
- Boronic Acid for the Traceless Delivery of Proteins into Cells. (2016) (36)
- Genetic selection for critical residues in ribonucleases. (2006) (35)
- Conformational preferences of substrates for human prolyl 4-hydroxylase. (2008) (35)
- Dibromobimane as a fluorescent crosslinking reagent. (1995) (34)
- Chemical mechanism of DNA cleavage by the homing endonuclease I-PpoI. (1999) (34)
- Bovine seminal ribonuclease produced from a synthetic gene. (1993) (34)
- Semisynthesis of proteins containing selenocysteine. (2002) (34)
- Production of human prolyl 4-hydroxylase in Escherichia coli. (2004) (34)
- Increasing the potency of a cytotoxin with an arginine graft. (2007) (34)
- Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif†,‡ (2009) (34)
- Peptides that anneal to natural collagen in vitro and ex vivo. (2012) (33)
- High-level soluble production and characterization of porcine ribonuclease inhibitor. (2001) (33)
- His...Asp catalytic dyad of ribonuclease A: conformational stability of the wild-type, D121N, D121A, and H119A enzymes. (1998) (33)
- A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells. (2008) (33)
- Mechanistic studies on reactions of bacterial methionine gamma-lyase with olefinic amino acids. (1981) (33)
- Anchoring a cytoactive factor in a wound bed promotes healing (2016) (33)
- Molecular basis for the autonomous promotion of cell proliferation by angiogenin (2016) (32)
- O‐acylation of hydroxyproline residues: Effect on peptide‐bond isomerization and collagen stability (2005) (32)
- n→π* Interactions Are Competitive with Hydrogen Bonds. (2016) (32)
- Characterization of protein immobilization at silver surfaces by near edge X-ray absorption fine structure spectroscopy. (2006) (32)
- Contribution of a tyrosine side chain to ribonuclease A catalysis and stability–Contribution of Tyr 97 to RNase A catalysis and stability (1996) (32)
- 4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins. (2017) (31)
- Fast, facile, hypersensitive assays for ribonucleolytic activity. (2001) (31)
- Degenerate DNA recognition by I-PpoI endonuclease. (1998) (31)
- 2005 Emil Thomas Kaiser Award (2006) (31)
- Pentavalent Organo-Vanadates as Transition State Analogues for Phosphoryl Transfer Reactions. (2000) (31)
- Rational design and evaluation of mammalian ribonuclease cytotoxins. (2012) (30)
- Conversion of azides into diazo compounds in water. (2013) (30)
- ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. (2009) (30)
- Target selection by natural and redesigned PUF proteins (2015) (29)
- Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells. (2006) (29)
- Simulated moving bed chromatography: separation and recovery of sugars and ionic liquid from biomass hydrolysates. (2013) (29)
- n→π* Interactions Modulate the Properties of Cysteine Residues and Disulfide Bonds in Proteins. (2018) (28)
- Separation of Lignin from Corn Stover Hydrolysate with Quantitative Recovery of Ionic Liquid. (2015) (28)
- Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma. (2018) (28)
- An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group. (2013) (28)
- Contribution of individual disulfide bonds to the oxidative folding of ribonuclease A. (2000) (28)
- Fluorogenic Assay for Inhibitors of HIV-1 Protease with Sub-picomolar Affinity (2015) (28)
- Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders. (2015) (28)
- The CXXC motif: crystal structure of an active-site variant of Escherichia coli thioredoxin. (1999) (28)
- No role for pepstatin-A-sensitive acidic proteinases in reovirus infections of L or MDCK cells. (1998) (27)
- A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus (2006) (27)
- Bovine Brain Ribonuclease Is the Functional Homolog of Human Ribonuclease 1* (2014) (27)
- Evolution of ribonuclease inhibitor by exon duplication. (2002) (27)
- Stereoelectronic effects impact glycan recognition. (2020) (27)
- Fluorescence assay for the binding of ribonuclease A to the ribonuclease inhibitor protein. (2002) (26)
- Immunosuppressive activity of bovine seminal ribonuclease and its mode of action. (1996) (26)
- Peptide tags for a dual affinity fusion system. (1994) (26)
- Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction. (2007) (26)
- Optimal Interstrand Bridges for Collagen-like Biomaterials (2014) (26)
- Practical syntheses of 4-fluoroprolines. (2008) (26)
- Insights on the Conformational Stability of Collagen (2002) (26)
- Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. (2016) (25)
- Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L (2015) (25)
- tRNA ligase catalyzes the GTP-dependent ligation of RNA with 3'-phosphate and 5'-hydroxyl termini. (2012) (25)
- Electronic and steric effects on the rate of the traceless Staudinger ligation. (2008) (25)
- Stringency of the 2-His–1-Asp Active-Site Motif in Prolyl 4-Hydroxylase (2009) (25)
- Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin. (2001) (25)
- Design and characterization of an HIV-specific ribonuclease zymogen. (2008) (25)
- Compensating effects on the cytotoxicity of ribonuclease A variants. (2003) (24)
- Mechanism-based enzyme inactivation using an allyl sulfoxide-allyl sulfenate ester rearrangement (1980) (24)
- Hox genes maintain critical roles in the adult skeleton (2020) (24)
- Thiols and selenols as electron-relay catalysts for disulfide-bond reduction. (2013) (24)
- Protein engineering with the traceless Staudinger ligation. (2009) (24)
- Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase. (2011) (24)
- Catalysis of protein disulfide bond isomerization in a homogeneous substrate. (2005) (24)
- Trimethyl Lock: A Stable Chromogenic Substrate for Esterases (2008) (23)
- Is glycine a surrogate for a d‐amino acid in the collagen triple helix? (2006) (22)
- Interaction of onconase with the human ribonuclease inhibitor protein. (2008) (22)
- Coulombic effects on the traceless Staudinger ligation in water. (2009) (22)
- Decreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions. (2016) (22)
- Comparative functional analysis of ribonuclease 1 homologs: molecular insights into evolving vertebrate physiology. (2017) (22)
- Antitumor activity of ribonuclease multimers created by site-specific covalent tethering. (2010) (22)
- Catalysis of Protein Folding by an Immobilized Small‐Molecule Dithiol (2008) (21)
- Contribution of electrostatics to the binding of pancreatic-type ribonucleases to membranes. (2013) (21)
- Contribution of tertiary amides to the conformational stability of collagen triple helices. (2001) (21)
- Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1 (2015) (21)
- Thermodynamic Origin of Prolyl Peptide Bond Isomers. (1993) (21)
- Nature's transitory covalent bond (1997) (20)
- Macrocyclic scaffold for the collagen triple helix. (2006) (20)
- Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides (2011) (20)
- Active Site of Ribonuclease A (2004) (20)
- Binding Energy and Enzymatic Catalysis (1990) (20)
- A misfolded but active dimer of bovine seminal ribonuclease. (1994) (20)
- Facile chemical functionalization of proteins through intein-linked yeast display. (2013) (20)
- Oligomers of a 5-carboxy-methanopyrrolidine β-amino acid. A search for order. (2010) (20)
- Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation. (2017) (20)
- Fluorogenic probe for constitutive cellular endocytosis. (2013) (19)
- An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins (2014) (19)
- Boronic acid with high oxidative stability and utility in biological contexts (2020) (19)
- Structure and stability of the P93G variant of ribonuclease A (1998) (19)
- 1,3-Dipolar Cycloaddition with Diazo Groups: Noncovalent Interactions Overwhelm Strain. (2016) (19)
- Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells. (2009) (19)
- Detection of boronic acids through excited-state intramolecular proton-transfer fluorescence. (2013) (19)
- Esterification Delivers a Functional Enzyme into a Human Cell. (2019) (18)
- Fluorogenic label to quantify the cytosolic delivery of macromolecules. (2013) (18)
- Ribonuclease-Activated Cancer Prodrug. (2012) (18)
- Modulation of an n→π* interaction with α-fluoro groups. (2010) (18)
- Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells. (2014) (18)
- n?p* interactions in proteins (2010) (18)
- Protein prosthesis: β‐peptides as reverse‐turn surrogates (2013) (17)
- Interstrand Dipole-Dipole Interactions Can Stabilize the Collagen Triple Helix* (2011) (17)
- Direct and continuous assay for prolyl 4-hydroxylase. (2009) (17)
- A novel fully human antitumor immunoRNase resistant to the RNase inhibitor. (2013) (17)
- Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases. (2016) (17)
- Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress (2019) (17)
- Separable fluorous ionic liquids for the dissolution and saccharification of cellulose (2011) (16)
- Production of rat protein disulfide isomerase in Saccharomyces cerevisiae. (1995) (16)
- First-in-human phase I clinical trial of QBI-139, a human ribonuclease variant, in solid tumors. (2012) (16)
- Sensitive fluorogenic substrate for alkaline phosphatase. (2011) (16)
- A highly active immobilized ribonuclease. (2000) (16)
- Human Collagen Prolyl 4-Hydroxylase Is Activated by Ligands for Its Iron Center. (2016) (16)
- Fluorescence gel retardation assay to detect protein-protein interactions. (2004) (15)
- Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging. (2017) (15)
- Replacing a single atom accelerates the folding of a protein and increases its thermostability. (2016) (15)
- Click Chemistry with Cyclopentadiene. (2021) (15)
- Excavating an active site: the nucleobase specificity of ribonuclease A. (2000) (15)
- Coevolution of RtcB and Archease created a multiple-turnover RNA ligase (2015) (15)
- Delivery of Proteins and Nucleic Acids: Achievements and Challenges. (2019) (15)
- Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity (2011) (14)
- Origin of the ‘inactivation’ of ribonuclease A at low salt concentration (2000) (14)
- An intuitive Approach to Steady-State Kinetics (1988) (14)
- An n→π* Interaction in the Bound Substrate of Aspartic Proteases Replicates the Oxyanion Hole. (2018) (14)
- Binding of non‐natural 3′‐nucleotides to ribonuclease A (2005) (14)
- Modulating collagen triple-helix stability with 4-chloro, 4-fluoro, and 4-methylprolines. (2009) (14)
- Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1. (2019) (14)
- Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent are Potent Inhibitors of Ribonuclease A. (2019) (14)
- Triple, Mutually Orthogonal Bioorthogonal Pairs through the Design of Electronically Activated Sulfamate-Containing Cycloalkynes. (2020) (14)
- High‐Yielding Staudinger Ligation of a Phosphinothioester and Azide to Form a Peptide. (2001) (13)
- A conserved interaction with the chromophore of fluorescent proteins (2012) (13)
- Hyperconjugative Antiaromaticity Activates 4H-Pyrazoles as Inverse-Electron-Demand Diels-Alder Dienes. (2019) (13)
- Structural changes to ribonuclease A and their effects on biological activity. (1999) (13)
- Sulfur shuffle: modulating enzymatic activity by thiol-disulfide interchange. (2000) (13)
- Enzyme relaxation in the reaction catalyzed by triosephosphate isomerase: detection and kinetic characterization of two unliganded forms of the enzyme. (1987) (13)
- Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A (2011) (13)
- Rapid cycloaddition of a diazo group with an unstrained dipolarophile. (2016) (12)
- Efficient metal-free conversion of glucose to 5-hydroxymethylfurfural using a boronic acid (2018) (12)
- Green fluorescent protein chimeras to probe protein-protein interactions. (2000) (12)
- Optimization of interstrand interactions enables burn detection with a collagen-mimetic peptide. (2019) (12)
- Disruption and formation of surface salt bridges are coupled to DNA binding by the integration host factor: a computational analysis. (2011) (12)
- Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates. (2015) (12)
- Protein Disulfide Isomerase : Cellular Enzymology of the CXXC Motif (2001) (12)
- Intraspecies regulation of ribonucleolytic activity. (2007) (12)
- Palladium-Protein Oxidative Addition Complexes by Amine-Selective Acylation. (2020) (12)
- Extending the limits to enzymatic catalysis: diffusion of ribonuclease A in one dimension. (1999) (12)
- 4‐ketoproline: An electrophilic proline analog for bioconjugation (2015) (11)
- Templated Collagen "Double Helices" Maintain Their Structure. (2020) (11)
- Human ribonuclease with a pendant poly(ethylene glycol) inhibits tumor growth in mice. (2013) (11)
- Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. (2011) (11)
- Cyclic Peptide Mimetic of Damaged Collagen (2020) (10)
- Fluorescence polarization assay to quantify protein-protein interactions: an update. (2015) (10)
- Cytosolic Uptake of Large Monofunctionalized Dextrans. (2018) (10)
- Site-Specific Antibody Functionalization Using Tetrazine-Styrene Cycloaddition. (2018) (10)
- Semisynthesis of Ribonuclease A using Intein-Mediated Protein Ligation (2002) (10)
- Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond. (2017) (10)
- Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. (2012) (10)
- Phenotype of ribonuclease 1 deficiency in mice (2019) (10)
- Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. (2002) (9)
- Genetic selection reveals the role of a buried, conserved polar residue (2007) (9)
- Site-specific folate conjugation to a cytotoxic protein. (2011) (9)
- Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme (2020) (9)
- Ribonuclease S redux. (2011) (9)
- Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase. (2014) (9)
- Abstract 1838: Efficacy of ribonuclease QBI-139 in combination with standard of care therapies (2012) (9)
- Optical imaging of collagen fiber damage to assess thermally injured human skin (2020) (9)
- Zinc(II)-mediated inhibition of a ribonuclease by an N-hydroxyurea nucleotide. (2003) (8)
- Ribonucleases endowed with specific toxicity for spermatogenic layers. (1997) (8)
- Pyramidalization of a carbonyl C atom in (2S)-N-(selenoacetyl)proline methyl ester (2013) (8)
- Effect of bovine seminal ribonuclease and bovine pancreatic ribonuclease A on bovine oocyte maturation. (2000) (8)
- Bioavailable affinity label for collagen prolyl 4-hydroxylase. (2013) (7)
- Genetic screen to dissect protein-protein interactions: ribonuclease inhibitor-ribonuclease A as a model system. (2002) (7)
- A pendant peptide endows a sunscreen with water-resistance. (2018) (7)
- Acceleration of 1,3-Dipolar Cycloadditions by Integration of Strain and Electronic Tuning. (2021) (7)
- Ribonuclease A: from Model System to Cancer Chemotherapeutic (1999) (7)
- Production of human pancreatic ribonuclease in Saccharomyces cerevisiae and Escherichia coli. (1996) (7)
- Staudinger ligation of alpha-azido acids retains stereochemistry. (2002) (7)
- n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines. (2020) (7)
- Genetic selection for peptide inhibitors of angiogenin. (2008) (7)
- Synthetic surfaces for ribonuclease adsorption. (2005) (7)
- Peptides on the Rise. (2017) (7)
- Trimethyl Lock: A Trigger for Molecular Release in Chemistry, Biology, and Pharmacology (2012) (6)
- The Mechanistic Pathway of a Mutant Triosephosphate Isomerase a (1986) (6)
- Pyrazine-derived disulfide-reducing agent for chemical biology. (2014) (6)
- Catalysis of Hydrogen-Deuterium Exchange Reactions by 4-Substituted Proline Derivatives. (2019) (6)
- A Divalent Protecting Group for Benzoxaboroles. (2013) (6)
- Ribonucleoside 3′‐Phosphates as Pro‐Moieties for an Orally Administered Drug (2012) (6)
- Protein disulfide isomerase in spore germination and cell division. (1997) (6)
- Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis. (2004) (6)
- Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer. (2011) (6)
- Role for Cell-Surface Collagen of Streptococcus pyogenes in Infection. (2020) (5)
- Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells. (2020) (5)
- Hyperconjugative π → σ*CF Interactions Stabilize the Enol Form of Perfluorinated Cyclic Keto-Enol Systems. (2019) (5)
- Creating site-specific isopeptide linkages between proteins with the traceless Staudinger ligation. (2015) (5)
- Convenient synthesis of collagen‐related tripeptides for segment condensation (2015) (5)
- Olefin Metathesis for Chemical Biology (2009) (5)
- Peptides and peptidomimetics as prototypes. (2008) (5)
- The extent to which ribonucleases cleave ribonucleic acid. (1995) (5)
- A Human Ribonuclease Variant and ERK-Pathway Inhibitors Exhibit Highly Synergistic Toxicity for Cancer Cells (2018) (5)
- PTENpred: A Designer Protein Impact Predictor for PTEN-related Disorders (2016) (5)
- Silencing an inhibitor unleashes a cytotoxic enzyme. (2009) (5)
- Affinity of monoclonal antibodies for Globo-series glycans. (2014) (5)
- Terbium(III) Luminescence-Based Assay for Esterase Activity. (2019) (5)
- 5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: a nucleophilic displacement route. (2009) (4)
- Emerging biological functions of ribonuclease 1 and angiogenin (2021) (4)
- Structure of RNA 3′-phosphate cyclase bound to substrate RNA (2014) (4)
- Assignments of RNase A by ADAPT-NMR and enhancer (2015) (4)
- Structure and Dynamics of N-Glycosylated Human Ribonuclease 1. (2020) (4)
- Crystal structure of N-(3-oxobutanoyl)-l-homoserine lactone (2016) (4)
- Signatures of n ! p * interactions in proteins (2014) (3)
- Mechanistic Studies on Reactions of Bacterial Methionine y-Lyase with Olefinic Amino Acidst (2002) (3)
- Model systems: This year's model (2002) (3)
- The kinetic consequences of altering the catalytic residues of triosephosphate isomerase (1986) (3)
- Cover Picture: Synthesis of Furfural from Xylose and Xylan (ChemSusChem 11/2010) (2010) (3)
- Synthesis and Diels–Alder Reactivity of 4-Fluoro-4-Methyl-4H-Pyrazoles (2020) (3)
- Two-Step Synthesis of α-Aryl-α-diazoamides as Modular Bioreversible Labels. (2021) (3)
- Differential Effects of Nitrogen-Substitution in 5- and 6-Membered Aromatic Motifs. (2020) (3)
- Disulfide Chromophores Arise from Stereoelectronic Effects. (2020) (2)
- Enzymes as Chemotherapeutic Agents (2012) (2)
- Circular zymogens of human ribonuclease 1 (2019) (2)
- Bifunctional Peptide that Anneals to Damaged Collagen and Clusters TGF-β Receptors Enhances Wound Healing (2021) (2)
- Stronger and (now) longer synthetic collagen. (2009) (2)
- Innentitelbild: Thiols and Selenols as Electron-Relay Catalysts for Disulfide-Bond Reduction (Angew. Chem. 49/2013) (2013) (2)
- Emil Thomas Kaiser Award (2006) (2)
- Inside Cover: A Phosphine‐Mediated Conversion of Azides into Diazo Compounds (Angew. Chem. Int. Ed. 13/2009) (2009) (2)
- Interactions Modulate the Properties of Cysteine Residues and Disul fi de Bonds in Proteins (2018) (2)
- One-dimensional diffusion of a protein along a single-stranded nucleic acid (1997) (2)
- Role for Cell-Surface Collagen of Streptococcus pyogenes in Infections (2020) (2)
- Intrinsic site‐selectivity of ubiquitin dimer formation (2015) (2)
- Canavanine versus arginine: Prospects for cell-penetrating peptides. (2022) (2)
- A substrate selected by phage display exhibits enhanced side-chain hydrogen bonding to HIV-1 protease. (2018) (2)
- ACTIVE-SITE VARIANT OF E.COLI THIOREDOXIN (1999) (1)
- Abstract 2573: Combinations of QBI-139, a clinical stage ribonuclease drug (2011) (1)
- Innentitelbild: A Phosphine‐Mediated Conversion of Azides into Diazo Compounds (Angew. Chem. 13/2009) (2009) (1)
- Biocalorimctry: Applications of Calorimetry in the Biological Sciences; Edited (1)
- Geminal Repulsion Disrupts Diels-Alder Reactions of Geminally Substituted Cyclopentadienes and 4H-Pyrazoles. (2021) (1)
- Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection (2021) (1)
- Emergent Organoboron Acid Catalysts. (2022) (1)
- Front Cover: Differential Effects of Nitrogen Substitution in 5‐ and 6‐Membered Aromatic Motifs (Chem. Eur. J. 41/2020) (2020) (1)
- Symbiosis: Chemical biology at Wisconsin. (2006) (1)
- A phase I clinical trial of QBI-139, a human ribonuclease variant, in solid tumors. (2011) (1)
- Context‐Dependence of the Reactivity of Cysteine and Lysine Residues (2022) (1)
- Host-Guest Complexation by β-Cyclodextrin Enhances the Solubility of an Esterified Protein. (2022) (1)
- The stereoelectronic basis of collagen stability (2002) (1)
- PROTEIN ASSEMBLY TO MINE THE HUMAN GENOME (2003) (1)
- Hyperstable collagen based on 4-fluoroproline residues (2007) (1)
- A Donor – Acceptor Perspective on Carbonyl – Carbonyl Interactions in Proteins (2010) (1)
- Altering Substrate Specificity and Detecting Processivity in Nucleases (1994) (1)
- Crystal structure of onconase with bound nucleic acid (2006) (1)
- Relationship of QBI-139, a human ribonuclease variant, and RNA in cancer cells. (2010) (1)
- Abstract 5390: QBI-139, a human RNase variant in a phase I trial, works in combination (2010) (1)
- Erratum: Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells (Protein Engineering, Design and Selection (2014) 27:3 (83-88) DOI: 10.1093/protein/gzt065) (2014) (1)
- Ribonucleases : Structures and junctions , edited (1)
- Crystal structure of onconase double mutant with spontaneously-assembled (AMP) 4 stack (2006) (1)
- Abstract C42: QBI‐139, a human RNase variant in a phase I trial, has broad in vivo efficacy (2009) (1)
- Endogenous Enzymes Enable Antimicrobial Activity. (2021) (1)
- Latent Fluorophores for Biomolecular Imaging (2008) (0)
- Stereoelectronically Stabilized Flurogenic Probes for Esterase–Activated Biomolecule Imaging (2017) (0)
- Dibromobimane as a Fluorescent Crosslin king Reagent (0)
- Effect of fluoro-substituted proline residues on the conformational stability of triple-helical collagen mimics (2002) (0)
- Use of a human ribonuclease variant, QBI-139, for the treatment of cancer. (2010) (0)
- Bioreversible Protein Labeling For Cellular Delivery (2015) (0)
- Structure of Archease from Pyrococcus horikoshii (2014) (0)
- Bioorthogonal 4H-pyrazole “click” reagents (2023) (0)
- Wild-type Transthyretin in complex with 3-[(1E)-2-(4-Boronic acid)ethenyl]benzoic Acid (2017) (0)
- RNase A in complex with hexametaphosphate (2019) (0)
- X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1 (2012) (0)
- Triple, Mutually Orthogonal Cycloadditions Through the Design of Electronically Activated SNO-OCTs (2020) (0)
- phosphate cyclase bound to substrate RNA ′ Structure of RNA 3 Material Supplemental (2014) (0)
- 347 POSTER Anti-cancer activity of human ribonuclease conjugates with enhanced pharmacokinetic profiles (2008) (0)
- Crystal Structure of fluorine and methyl modified collagen: (mepFlpgly)7 (2010) (0)
- PROTEIN ACTIVATION A site-specific small-molecule switch DIGERMANIUM COMPLEXES Heavy vinylidene drops the base SOLUTE DYNAMICS The cooling-off period (2016) (0)
- STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A (1998) (0)
- The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine (2003) (0)
- Semisynthesis of Human Ribonuclease-S. (2020) (0)
- Ribonuclease A and Its Homologues Bovine pancreatic ribonuclease (2013) (0)
- THR45GLY VARIANT OF RIBONUCLEASE A (2002) (0)
- Neuroprotective Effect Of Tris(2–carboxyethyl)phosphine (TCEP) In An Optic Nerve Crush Model In The Rat (2004) (0)
- Ribonuclease cytotoxique produite par genie genetique (1999) (0)
- Author ' s personal copy Sensitive fluorogenic substrate for alkaline phosphatase (2011) (0)
- Contribution of mainchain-mainchain hydrogen bonds to the conformational stability of triple-helical collagen (2002) (0)
- Theoretical Analysis of the Basis of Collagen Stability (2005) (0)
- Spirocyclization enhances the Diels-Alder reactivities of geminally substituted cyclopentadienes and 4H-pyrazoles. (2022) (0)
- Stronger and Longer Synthetic Collagen (2007) (0)
- HIV-1 protease (D25N, inactive) in complex with phage display optimized substrate SGIFLETS (2018) (0)
- Interactions in the Molecules of Life (2010) (0)
- The n → π * Interaction Published as part of the Accounts of Chemical Research special issue “ Chemical Biology of Peptides ” (2017) (0)
- Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I (2014) (0)
- Self-Assembly of Collagen Mimetic Peptides (2006) (0)
- A Highly Sensitive Fluorogenic Probe for Cytochrome P450 Activity in Live Cells (2009) (0)
- Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs. (2020) (0)
- Selective and Bioavailable Inhibitors of Collagen Prolyl 4‐Hydroxylase (2015) (0)
- Wild-type HIV-1 protease in complex with a phenylboronic acid (P2') analog of darunavir (2018) (0)
- Role for Cell-SurfaceCollagen of Streptococcuspyogenes in Infections (2020) (0)
- H119A VARIANT OF RIBONUCLEASE A (2001) (0)
- Assignments of RNase A by ADAPT-NMR and enhancer (2014) (0)
- Chemoselective Caging of Carboxyl Groups for On-Demand Protein Activation with Small Molecules. (2023) (0)
- Wild-type Transthyretin in complex with 5-[(1E)-2-(4-Boronic acid)ethenyl]-1,3-benzenediol (2017) (0)
- Structure of bovine ribonuclease inhibitor complexed with bovine ribonuclease I (2014) (0)
- Modular Diazo Compound for the Bioreversible Late-Stage Modification of Proteins. (2023) (0)
- Design of phase 1 trial of a human ribonuclease variant (2008) (0)
- Toxicology of a potent human RNase variant (2007) (0)
- Wild-type Transthyretin in complex with 5-[(1E)-2-(2-Chloro-4-hydroxyphenyl)ethenyl]-1,3-benzenediol (2017) (0)
- Inside Cover: Thiols and Selenols as Electron‐Relay Catalysts for Disulfide‐Bond Reduction (Angew. Chem. Int. Ed. 49/2013) (2013) (0)
- 408 POSTER Human RNase 1 variants are effective anti-cancer agents (2006) (0)
- Peptides and peptidomimetics as prototypes Editorial overview (2008) (0)
- RNase A in complex with cp4pA (2019) (0)
- Chemical consequences of prolyl hydroxylation (2010) (0)
- Wild-type Transthyretin in complex with 2-Boronic Acid-1-[(1E)-2-(3-boronic acid)ethenyl]-4-chlorobenzene (2017) (0)
- Modulating the conformational stability of triple-helical collagen by chemical modification (2002) (0)
- Protein Assembly Using the Staudinger Ligation (2005) (0)
- Wild-type Transthyretin in complex with 3-[(1E)-2-(2-Chloro-4-hydroxyphenyl)ethenyl]benzoic Acid (2017) (0)
- Not just for Patterning: Hox Genes Function in the Adult Mammalian Skeleton (2020) (0)
- Semisynthesis of Protein variants Using Intein-Mediated Protein Ligation (2001) (0)
- Correction: Symbiosis: Chemical Biology at Wisconsin (2006) (0)
- Wild-type Transthyretin in complex with 1,1'-(1E)-(1,2-Ethenediyl)bis[2-chloro-4-boronic acid]benzene (2017) (0)
- The Main-Chain Oxygen: Unappreciated Effects on Peptide and Protein Structure (2015) (0)
- Wild-type Transthyretin in complex with 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]benzoic Acid (2017) (0)
- Assessing and utilizing esterase specificity in antimicrobial prodrug development. (2022) (0)
- Daniel S. Kemp (1936-2020): A Pioneer of Bioorganic Chemistry. (2020) (0)
- RNase A in complex with p5U (2019) (0)
- Cover Image (2007) (0)
- Abstract 4405: RNases: Approaching RNA as a target for cancer therapy. (2013) (0)
- Inhibiteurs de la collagène prolyl-4-hydroxylase (2016) (0)
- Crystal structure of RtcA, the RNA 3'-terminal phosphate cyclase from Pyrococcus horikoshii. (2014) (0)
- Inside Cover: Ribonucleoside 3′‐Phosphates as Pro‐Moieties for an Orally Administered Drug (ChemMedChem 8/2012) (2012) (0)
- Effect of 4-Fluoroproline in the X-Position on the Stability of the Collagen Triple Helix (2005) (0)
- RNase A in complex with p5A (2019) (0)
- Accelerated Publications May 24 , 1994 Structural Determinants of Enzymatic Processivity ? (2001) (0)
- Novel Ribonuclease Shows Antitumor Activity in Pancreatic Cancer and Mesothelioma , Onclology Times (2017) (0)
- Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen Clostridioides difficile (2022) (0)
- Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability. (2023) (0)
- FORTHERECORD Signature of nfip* interactions in a-helices (2011) (0)
- Practical Synthesis of 4-Fluoroprolines. (2009) (0)
- Loss of Rnase1 Produces Coagulation Abnormalities in Mice (2017) (0)
- Ribonuclease S redux w z (2010) (0)
- n→π* Interactions in Helices (2013) (0)
- RNA Ligase RtcB in complex with Mn(II) (2013) (0)
- Structure of the RNA ligase RtcB-GMP/Mn(II) complex (2013) (0)
- D30N HIV-1 protease in complex with a phenylboronic acid (P2') analog of darunavir (2018) (0)
- Efficient metal-free conversion of glucose to 5-hydroxymethylfurfural using a boronic acid (2018) (0)
- STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A COMPLEXED WITH 3'-UMP (1998) (0)
- ILV/VI-13 MODERN PROTEIN CHEMISTRY(Molecular Mode of Action on Natural Products and Drugs/Chemical Biology and Related Areas) (2006) (0)
- Crystal structure of RNase Sa3,cytotoxic microbial ribonuclease (2003) (0)
- 1,9-Bis(2-pyridyl)-1,2,8,9-tetrathia-5-oxanonane (2009) (0)
- Wild-type Transthyretin in complex with 3-[(1E)-2-(2-Chloro-4-boronic acid)ethenyl]benzoic Acid (2017) (0)
- RNA ligase RtcB in complex with GTP alphaS and Mn(II) (2013) (0)
- Wild-type Transthyretin in complex with 5-[(1E)-2-(2-Chloro-4-boronic acid)ethenyl]-1,3-benzenediol (2017) (0)
- Transthyretin in complex with (E)-5,5'-(ethene-1,2-diyl)bis(1,1-dihydroxy-3-oxo-1,3-dihydrobenzo[c][1,2]oxaborol-1-uide) (2021) (0)
- STRUCTURE OF THE P93G VARIANT OF RIBONUCLEASE A (1998) (0)
- Monofunctionalization with dextrans endows cell‐penetrative properties to proteins (2019) (0)
- human ribonuclease with reduced affinity ribonuclease inhibitor. (1998) (0)
- STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A (1998) (0)
- TOWARDS SYNTHETIC COLLAGEN (2005) (0)
- Graft Copolymers from a Double ROMP (2009) (0)
- Pre-clinical toxicology for a potent anti-cancer agent, a human ribonuclease variant (2007) (0)
- Human ribonuclease variants with broad anti-cancer activity (2006) (0)
- Structure of Human Intelectin-1 in complex with KO (2020) (0)
- A Phosphine‐Mediated Conversion of Azides into Diazo Compounds. (2009) (0)
- Modular SNO-OCT scaffolds for multiple, rapid bioorthogonal labeling (2020) (0)
- Antagonists of ribonuclease inhibitor: Small molecules, dendrimers, and peptides (2008) (0)
- Intracellular Delivery of Functional Proteins (2022) (0)
- Anaerobic 4‐Hydroxyproline Metabolism by a Widespread Microbial Glycyl Radical Enzyme (2018) (0)
- Nα‐Methylation of arginine: Implications for cell‐penetrating peptides (2022) (0)
- Substrate specificity and conformational preferences of prolyl 4‐hydroxylase (2008) (0)
- Collagen Mimetic Peptides as Probes for Bacterial Infection (2017) (0)
- Ribonuclease: From kcat/KM to the Clinic (2018) (0)
- Crystal structure of RtcA, the RNA 3'-terminal phosphate cyclase from Pyrococcus horikoshii, in complex with rACAAA3'phosphate and adenine. (2014) (0)
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