Ronald Vale
Biochemist
Ronald Vale's AcademicInfluence.com Rankings
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Biology
Ronald Vale's Degrees
- PhD Biochemistry Stanford University
- Bachelors Biochemistry University of California, Santa Barbara
Why Is Ronald Vale Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ronald David Vale ForMemRS is an American biochemist and cell biologist. He is a professor at the Department of Cellular and Molecular Pharmacology, University of California, San Francisco. His research is focused on motor proteins, particularly kinesin and dynein. He was awarded the Canada Gairdner International Award for Biomedical Research in 2019, the Shaw Prize in Life Science and Medicine in 2017 together with Ian Gibbons, and the Albert Lasker Award for Basic Medical Research in 2012 alongside Michael Sheetz and James Spudich. He is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. He was the president of the American Society for Cell Biology in 2012. He has also been an investigator at the Howard Hughes Medical Institute since 1995. In 2019, Vale was named executive director of the Janelia Research Campus and a vice president of HHMI; his appointment began in early 2020.
Ronald Vale's Published Works
Published Works
- Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility (1985) (1865)
- The Molecular Motor Toolbox for Intracellular Transport (2003) (1822)
- Computer Control of Microscopes Using µManager (2010) (1424)
- Advanced methods of microscope control using μManager software. (2014) (1343)
- The way things move: looking under the hood of molecular motor proteins. (2000) (1341)
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging (2014) (1089)
- T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition (2016) (1028)
- Circularization of mRNA by eukaryotic translation initiation factors. (1998) (968)
- Kinesin Walks Hand-Over-Hand (2004) (931)
- Movement of microtubules by single kinesin molecules (1989) (854)
- A structural change in the kinesin motor protein that drives motility (1999) (769)
- Single-Molecule Microscopy Reveals Plasma Membrane Microdomains Created by Protein-Protein Networks that Exclude or Trap Signaling Molecules in T Cells (2005) (769)
- A standardized kinesin nomenclature (2004) (750)
- Phase separation of signaling molecules promotes T cell receptor signal transduction (2016) (728)
- Direct observation of single kinesin molecules moving along microtubules (1996) (685)
- Functional genomic screen reveals genes involved in lipid-droplet formation and utilization (2008) (655)
- Crystal structure of the kinesin motor domain reveals a structural similarity to myosin (1996) (638)
- Regulators of the cytoplasmic dynein motor (2009) (630)
- Single-Molecule Analysis of Dynein Processivity and Stepping Behavior (2006) (609)
- Genes Required for Mitotic Spindle Assembly in Drosophila S2 Cells (2007) (561)
- RNA Phase Transitions in Repeat Expansion Disorders (2017) (530)
- The design plan of kinesin motors. (1997) (511)
- Mechanism of Prion Propagation: Amyloid Growth Occurs by Monomer Addition (2004) (509)
- Aaa Proteins (2000) (506)
- Identification of katanin, an ATPase that severs and disassembles stable microtubules (1993) (501)
- Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. (2000) (475)
- Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes (2014) (447)
- Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro (1985) (444)
- Regulation of microtubule motors by tubulin isotypes and posttranslational modifications (2014) (440)
- Molecular requirements for actin-based lamella formation in Drosophila S2 cells (2003) (434)
- Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle (2002) (432)
- Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast (1997) (414)
- The cytoplasmic dynein transport machinery and its many cargoes (2018) (377)
- Force-Induced Bidirectional Stepping of Cytoplasmic Dynein (2007) (375)
- Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle (2008) (372)
- Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters (2012) (372)
- Microtubule Interaction Site of the Kinesin Motor (1997) (368)
- Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells (2007) (364)
- Single microtubules from squid axoplasm support bidirectional movement of organelles (1985) (349)
- Rapid Movements of Vimentin on Microtubule Tracks: Kinesin-dependent Assembly of Intermediate Filament Networks (1998) (348)
- Crystal structure of the motor domain of the kinesin-related motor ncd (1996) (346)
- Intracellular transport using microtubule-based motors. (1987) (343)
- Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase (2004) (336)
- Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon (1985) (332)
- The Directional Preference of Kinesin Motors Is Specified by an Element outside of the Motor Catalytic Domain (1997) (330)
- Dynamics of Translation of Single mRNA Molecules In Vivo (2016) (330)
- Katanin, a Microtubule-Severing Protein, Is a Novel AAA ATPase that Targets to the Centrosome Using a WD40-Containing Subunit (1998) (328)
- RNA on the move: the mRNA localization pathway [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1625] (1993) (322)
- Role of Phosphatidylinositol(4,5)bisphosphate Organization in Membrane Transport by the Unc104 Kinesin Motor (2002) (319)
- Branching Microtubule Nucleation in Xenopus Egg Extracts Mediated by Augmin and TPX2 (2013) (309)
- The Bipolar Kinesin, KLP61F, Cross-links Microtubules within Interpolar Microtubule Bundles of Drosophila Embryonic Mitotic Spindles (1999) (308)
- Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis (2003) (303)
- Walking the walk: how kinesin and dynein coordinate their steps. (2009) (299)
- Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin (2008) (293)
- Intramolecular Strain Coordinates Kinesin Stepping Behavior along Microtubules (2008) (290)
- Biophysical Mechanism of T Cell Receptor Triggering in a Reconstituted System (2012) (289)
- Engineering the Processive Run Length of the Kinesin Motor (2000) (286)
- Mechanisms for focusing mitotic spindle poles by minus end–directed motor proteins (2005) (279)
- Length Control of the Metaphase Spindle (2005) (271)
- Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon (1985) (267)
- Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain (1999) (267)
- Switches, latches, and amplifiers: common themes of G proteins and molecular motors (1996) (265)
- Crystal Structure of the Dynein Motor Domain (2011) (260)
- Mini-Review AAA Proteins: Lords of the Ring (2000) (255)
- Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. (2007) (249)
- The load dependence of kinesin's mechanical cycle. (1997) (247)
- Patronin Regulates the Microtubule Network by Protecting Microtubule Minus Ends (2010) (239)
- Drosophila RhoGEF2 Associates with Microtubule Plus Ends in an EB1-Dependent Manner (2004) (238)
- Rotation and translocation of microtubules in vitro induced by dyneins from Tetrahymena cilia (1988) (234)
- The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells (2009) (234)
- Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore (2007) (232)
- Structure and Functional Role of Dynein's Microtubule-Binding Domain (2008) (230)
- Conversion of Unc104/KIF1A Kinesin into a Processive Motor After Dimerization (2002) (229)
- Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin. (1999) (226)
- The roles of microtubule-based motor proteins in mitosis (2003) (217)
- Making Microtubules and Mitotic Spindles in Cells without Functional Centrosomes (2006) (215)
- The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. (2000) (211)
- Direction determination in the minus-end-directed kinesin motor ncd (1998) (209)
- Protein motors and Maxwell's demons: does mechanochemical transduction involve a thermal ratchet? (1990) (204)
- Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end (2005) (195)
- Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors (2006) (194)
- Severing of stable microtubules by a mitotically activated protein in xenopus egg extracts (1991) (191)
- Tuning the Antigen Density Requirement for CAR T Cell Activity. (2020) (182)
- Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides (1992) (182)
- Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells (1992) (179)
- The Drosophila Homologue of the Hereditary Spastic Paraplegia Protein, Spastin, Severs and Disassembles Microtubules (2005) (175)
- Role of the kinesin neck linker and catalytic core in microtubule-based motility (2000) (172)
- Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding (2018) (170)
- Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport (1996) (169)
- The Affinity of the Dynein Microtubule-binding Domain Is Modulated by the Conformation of Its Coiled-coil Stalk*[boxs] (2005) (167)
- Architectures of Lipid Transport Systems for the Bacterial Outer Membrane (2016) (166)
- Formation of membrane networks in vitro by kinesin-driven microtubule movement (1988) (166)
- One-dimensional diffusion of microtubules bound to flagellar dynein (1989) (164)
- A Model for the Microtubule-Ncd Motor Protein Complex Obtained by Cryo-Electron Microscopy and Image Analysis (1997) (157)
- Role of the Kinesin Neck Region in Processive Microtubule-based Motility (1998) (156)
- Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin (2009) (154)
- How kinesin waits between steps (2007) (154)
- Cloning and localization of a conventional kinesin motor expressed exclusively in neurons (1994) (152)
- Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase (2005) (152)
- Isolation of a Ribonucleoprotein Complex Involved in mRNA Localization in Drosophila Oocytes (2000) (149)
- Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells. (2005) (145)
- Cell cycle control of microtubule-based membrane transport and tubule formation in vitro (1991) (144)
- Polarized Myosin Produces Unequal-Size Daughters During Asymmetric Cell Division (2010) (144)
- Katanin, the microtubule-severing ATPase, is concentrated at centrosomes. (1996) (142)
- Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility (2016) (142)
- Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation*S⃞ (2008) (142)
- Chimeric antigen receptors that trigger phagocytosis (2018) (142)
- The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans. (2004) (142)
- Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins (1992) (141)
- Characterization of the microtubule movement produced by sea urchin egg kinesin. (1987) (140)
- Thermodynamic properties of the kinesin neck-region docking to the catalytic core. (2003) (136)
- The case for a common ancestor: kinesin and myosin motor proteins and G proteins (1998) (131)
- Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing conformational change. (2000) (130)
- A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination (2017) (129)
- The Khd1 protein, which has three KH RNA‐binding motifs, is required for proper localization of ASH1 mRNA in yeast (2002) (129)
- Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. (1996) (129)
- Imaging individual green fluorescent proteins (1997) (128)
- Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin (2014) (125)
- Accelerating scientific publication in biology (2015) (125)
- Regulation of mRNA translation during mitosis (2015) (123)
- One motor, many tails: An expanding repertoire of force-generating enzymes (1990) (123)
- Microtubule nucleation at the centrosome and beyond (2015) (120)
- Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. (2005) (120)
- In vitro membrane reconstitution of the T cell receptor proximal signaling network (2014) (119)
- Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. (2005) (118)
- Preprints for the life sciences (2016) (117)
- Fast transport of neurofilament protein along microtubules in squid axoplasm. (2000) (116)
- Single-molecule observations of neck linker conformational changes in the kinesin motor protein (2006) (114)
- Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3 (2006) (112)
- How Dynein Moves Along Microtubules. (2016) (112)
- Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3 (2016) (111)
- A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd (2006) (108)
- Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules. (1994) (107)
- The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells (2009) (106)
- Total Internal Reflection Fluorescence Microscopy. (2015) (104)
- Three-dimensional structure of a tubulin-motor-protein complex (1995) (102)
- Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays? (2006) (100)
- Myosin V motor proteins (2003) (98)
- Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles (2003) (98)
- Chemomechanical cycle of kinesin differs from that of myosin (1993) (95)
- Movement of membrane tubules along microtubules in vitro: evidence for specialised sites of motor attachment. (1994) (94)
- μManager: Open Source Software for Light Microscope Imaging (2007) (93)
- Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts (2011) (93)
- Assaying binding of nerve growth factor to cell surface receptors. (1985) (90)
- Determinants of Myosin II Cortical Localization during Cytokinesis (2010) (88)
- Allosteric Communication in the Dynein Motor Domain (2014) (87)
- Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. (2004) (85)
- Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition (2003) (84)
- De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy (2015) (83)
- Alteration of binding properties and cytoskeletal attachment of nerve growth factor receptors in PC12 cells by wheat germ agglutinin (1982) (82)
- Demonstration of Coiled-Coil Interactions within the Kinesin Neck Region Using Synthetic Peptides (1997) (82)
- Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell (2012) (79)
- Ten simple rules to consider regarding preprint submission (2017) (79)
- Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae. (2005) (77)
- Clustering of a kinesin-14 motor enables processive retrograde microtubule-based transport in plants (2015) (77)
- Kinesin: possible biological roles for a new microtubule motor (1986) (77)
- CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. (2020) (77)
- Inhibitors of kinesin activity from structure-based computer screening. (2000) (76)
- Altered Actin Centripetal Retrograde Flow in Physically Restricted Immunological Synapses (2010) (75)
- Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains (2013) (73)
- A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region (2014) (73)
- Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells (2009) (69)
- Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin (1991) (69)
- Drosophila Pod-1 Crosslinks Both Actin and Microtubules and Controls the Targeting of Axons (2003) (69)
- Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment (2010) (69)
- Single-molecule behavior of monomeric and heteromeric kinesins. (1999) (69)
- Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis (2016) (67)
- In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase (2017) (66)
- Mitotic Phosphorylation of the Dynein Light Intermediate Chain is Mediated by cdc2 Kinase (2000) (64)
- Staying on Track: Common Features of DNA Helicases and Microtubule Motors (1998) (64)
- A composition-dependent molecular clutch between T cell signaling condensates and actin (2018) (62)
- Reconstitution of Membrane Transport Powered by a Novel Dimeric Kinesin Motor of the Unc104/Kif1a Family Purified from Dictyostelium (1999) (60)
- Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells (2013) (58)
- Motor Protein Receptors Moonlighting on Other Jobs (2000) (58)
- Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends (2005) (57)
- Kinesin-73 Is a Processive Motor That Localizes to Rab5-containing Organelles* (2010) (56)
- The mechanism of dynein motility: insight from crystal structures of the motor domain. (2012) (55)
- Closing of the Nucleotide Pocket of Kinesin-Family Motors upon Binding to Microtubules (2003) (55)
- Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia (2018) (52)
- Association of nerve growth factor receptors with the triton X-100 cytoskeleton of PC12 cells (1985) (52)
- Disease-associated mutations in human BICD2 hyperactivate motility of dynein–dynactin (2017) (52)
- Assaying processive movement of kinesin by fluorescence microscopy. (1998) (51)
- Microtubule translocation properties of intact and proteolytically digested dyneins from Tetrahymena cilia (1989) (50)
- Publish peer reviews (2018) (50)
- Imaging and nano-manipulation of single biomolecules. (1997) (50)
- Movement of scallop myosin on Nitella actin filaments: regulation by calcium. (1984) (47)
- A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell–cell adhesion (2014) (46)
- Microtubule motors: many new models off the assembly line. (1992) (45)
- Molecular signatures of cell migration in C. elegans Q neuroblasts (2009) (45)
- Identification of a kinesin‐like microtubule‐based motor protein in Dictyostelium discoideum. (1989) (44)
- A novel method of affinity‐purifying proteins using a bis‐arsenical fluorescein (2008) (42)
- High-content imaging-based pooled CRISPR screens in mammalian cells (2020) (40)
- Interactions of the chemotaxis signal protein CheY with bacterial flagellar motors visualized by evanescent wave microscopy (2000) (39)
- Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles (2018) (39)
- In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain. (1998) (39)
- Tyrosination of α-Tubulin Controls The Initiation of Processive Dynein-Dynactin Motility (2015) (39)
- Coordinate control of translation and localization of Vg1 mRNA in Xenopus oocytes. (2000) (38)
- CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic (2019) (37)
- Searching for kinesin's mechanical amplifier. (2000) (37)
- Millennial musings on molecular motors. (1999) (37)
- Nucleotide specificities of anterograde and retrograde organelle transport in Reticulomyxa are indistinguishable (1991) (36)
- Communication between the AAA+ ring and microtubule-binding domain of dynein. (2010) (36)
- Conversion of nerve growth factor-receptor complexes to a slowly dissociating, Triton X-100 insoluble state by anti nerve growth factor antibodies. (1983) (35)
- Expression, purification, ATPase properties, and microtubule-binding properties of the ncd motor domain. (1995) (34)
- Single-molecule fluorescence detection of green fluorescence protein and application to single-protein dynamics. (1999) (33)
- HkRP3 Is a Microtubule-Binding Protein Regulating Lytic Granule Clustering and NK Cell Killing (2015) (33)
- A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis (2010) (33)
- Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions. (2020) (32)
- Vesicle Movements and Microtubule-Based Motors (1986) (32)
- Comparison of the motile and enzymatic properties of two microtubule minus-end-directed motors, ncd and cytoplasmic dynein. (1995) (32)
- Microtubule-based motor proteins. (1990) (32)
- Mob4 plays a role in spindle focusing in Drosophila S2 cells (2008) (31)
- ATPase kinetic characterization and single molecule behavior of mutant human kinesin motors defective in microtubule-based motility. (2000) (31)
- The myosin motor , Myo 4 p , binds Ash 1 mRNA via the adapter protein , She 3 p (2000) (31)
- EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. (2003) (30)
- Differential Expression of Ubiquitous and Neuronal Kinesin Heavy Chains During Differentiation of Human Neuroblastoma and PC12 Cells (1996) (29)
- Interdisciplinary Graduate Training in Teaching Labs (2012) (28)
- Hormone-induced modification of EGF receptor proteolysis in the induction of EGF action. (1979) (28)
- Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR) (2019) (28)
- Kinesin motors and microtubule-based organelle transport in Dictyostelium discoideum (2004) (25)
- Priority of discovery in the life sciences (2016) (25)
- The Arf GAP CNT-2 Regulates the Apoptotic Fate in C. elegans Asymmetric Neuroblast Divisions (2011) (25)
- A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging (2019) (24)
- High-resolution tracking of microtubule motility driven by a single kinesin motor. (1994) (24)
- Electron cryotomography of intact motile cilia defines the basal body to axoneme transition (2019) (24)
- Getting a grip on myosin (1994) (23)
- Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating (2020) (23)
- Evaluating how we evaluate (2012) (23)
- Single-molecule imaging of fluorescent proteins. (2008) (23)
- Impact of New Camera Technologies on Discoveries in Cell Biology (2016) (23)
- Cell Cycle-dependent Dynamics and Regulation of Mitotic Kinesins in Drosophila S 2 Cells □ (2005) (23)
- Microtubules and the Mechanism of Directed Organelle Movement (1986) (22)
- Microscopes for Fluorimeters: The Era of Single Molecule Measurements (2008) (22)
- Reconstitution of TCR Signaling Using Supported Lipid Bilayers. (2017) (22)
- Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. (2004) (22)
- New cytoskeletal liaisons (1992) (20)
- Controlling Kinesin by Reversible Disulfide Cross-Linking (2000) (20)
- Micro-Magellan: open-source, sample-adaptive, acquisition software for optical microscopy (2016) (19)
- A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum. (1998) (18)
- Nanometer-accuracy distance measurements between fluorophores at the single-molecule level (2019) (17)
- Partial characterization of a growth-inhibiting protein in 3T3 cell plasma membranes. (1982) (17)
- The value of asking questions (2013) (15)
- Measurement of the isometric force exerted by a single kinesin molecule. (1995) (15)
- Tracking Movements of the Microtubule Motors Kinesin and Dynein Using Total Internal Reflection Fluorescence Microscopy. (2015) (14)
- Spatial control of Draper receptor signaling initiates apoptotic cell engulfment (2018) (14)
- DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation (2021) (14)
- Autophagy genes promote apoptotic cell corpse clearance (2012) (13)
- Induction of focal adhesions and motility in Drosophila S2 cells (2014) (12)
- Sialic acid residues on NGF receptors on PC12 cells. (1985) (12)
- Measuring single protein motors at work. (1993) (12)
- Motile Properties of Cytoplasmic Dynein (2012) (12)
- Three-dimensional structure of the motor domain of NCD, a kinesin-related motor with reversed polarity of movement (1996) (12)
- A one‐hybrid system for detecting RNA–protein interactions (1996) (11)
- Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain (2019) (11)
- Purified plasma membranes inhibit polypeptide growth factor-induced DNA synthesis in subconfluent 3T3 cells (1984) (11)
- Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes (2018) (10)
- A new direction for kinesin (1990) (9)
- An acquisition and analysis pipeline for scanning angle interference microscopy (2016) (9)
- It's a Wonderful Life: A Career as an Academic Scientist (2010) (9)
- CD47 suppresses phagocytosis by repositioning SIRPA and preventing integrin activation (2019) (8)
- Use of ATP analogs in motor assays. (1993) (8)
- Kinesin into a Processive Motor After Dimerization (8)
- Introducing simulated cellular architecture to the quantitative analysis of fluorescent microscopy. (2009) (8)
- Dynein-Microtubule Interactions (1991) (8)
- Three-color single-molecule imaging reveals conformational dynamics of dynein undergoing motility (2020) (7)
- A new cap for kinetochore fibre minus ends (2011) (7)
- A tribute to Shinya Inoue and innovation in light microscopy (2004) (7)
- Cell Sorting in Hydra vulgaris Arises from Differing Capacities for Epithelialization between Cell Types (2020) (7)
- Retraction for Reck-Peterson et al., Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae, PNAS 2004 101:1491-1495 (2004) (6)
- The biological sciences in India Aiming high for the future (2009) (6)
- Supplemental Data Structural Basis of Microtubule Plus End Tracking by XMAP 215 , CLIP-170 , and EB 1 (2007) (6)
- The actin cytoskeleton governs apical mitosis and daughter cell dispersion in intestinal epithelia (2017) (6)
- Kinesin-based organelle transport (1994) (6)
- The Interaction of Nerve Growth Factor with Its Specific Receptors (1984) (6)
- Mechanisms of Chimeric Antigen Receptor (CAR) Signaling during T Cell Activation (2018) (6)
- The biological sciences in India (2009) (5)
- Not just Salk (2017) (5)
- Preface: the role of reconstitution in cytoskeleton research. (2014) (5)
- A brave new world for dynein (1991) (5)
- In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes (2022) (4)
- Mob 4 plays a role in spindle focusing in Drosophila S 2 cells (4)
- Stalk-mediated communication in the dynein motor domain (2018) (4)
- Cell biology. New cytoskeletal liaisons. (1992) (4)
- Author response: Regulation of mRNA translation during mitosis (2015) (4)
- Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain (2019) (3)
- Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis (2021) (3)
- Tight nanoscale clustering of Fcγ-receptors using DNA origami promotes phagocytosis (2021) (3)
- Young Leaders for Biology in India (2010) (3)
- Isolation and visualization of a structural trigger that uncouples TCR signaling from pMHC binding (2018) (3)
- Abstract A087: Phase separation of signaling molecules promotes T cell receptor signal transduction (2016) (3)
- Regulation of insulin receptors in frog erythrocytes by insulin and concanavalin A. Evidence for discrete classes of insulin binding sites. (1982) (3)
- Priority of discovery in the life (2016) (3)
- In Vitro Reconstitution of T Cell Receptor–Mediated Segregation of the CD45 Phosphatase (2017) (3)
- Signal Transduction Through a DNA-Based T Cell Receptor (2016) (3)
- Characterization of a microtubule assembly inhibitor from Xenopus oocytes. (2000) (2)
- MinireviewMotor Protein Receptors : Moonlighting on Other Jobs docking of motor proteins (2000) (2)
- De novo protein identification in mammalian sperm using high-resolution in situ cryo-electron tomography (2022) (2)
- Mechanical stretch regulates macropinocytosis in Hydra vulgaris (2021) (2)
- High accuracy measurements of nanometer-scale distances between fluorophores at the single-molecule level (2017) (2)
- Cell biology. A new direction for kinesin. (1990) (2)
- Creating opportunities for science PhDs to pursue careers in high school education (2013) (2)
- Keep Your Eyes on the Prize (2019) (2)
- In Vitro Studies of Microtubule Structures Using the Mac Mode AFM (1999) (1)
- Author response: Chimeric antigen receptors that trigger phagocytosis (2018) (1)
- A Structural and Functional Analysis of the Dynein Light Intermediate Chain (2014) (1)
- A data acquisition and analysis pipeline for scanning angle interference microscopy (2016) (1)
- Motor proteins. A brave new world for dynein. (1991) (1)
- Abstract PR05: Using genome-scale CRISPR-mediated loss-of-function and gain-of-function screens to analyze gene-drug interactions in cancer (2015) (1)
- ReviewThe Molecular Motor Toolbox for Intracellular Transport (2003) (1)
- A new calcium-activated dynein adaptor protein, CRACR2a, regulates clathrin-independent endocytic traffic in T cells (2018) (1)
- Reconstituting the cytoskeleton (2014) (1)
- Tracking Dynein Stepping along Microtubules using Multi-Color High Resolution Imaging (2017) (1)
- Ten simple rules for considering preprints (2016) (1)
- How lucky can one be? A perspective from a young scientist at the right place at the right time (2012) (1)
- A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging (2020) (1)
- The Binding and Internalization of Nerve Growth Factor (1983) (1)
- Crystal structure of the dynein motor domain in the AMPPNP-bound state (2014) (1)
- Insights into centriole biogenesis and evolution revealed by cryoTomography of doublet and triplet centrioles (2018) (1)
- Author response: Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains (2013) (1)
- HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN (1998) (0)
- Abstract A165: Engineering approaches to uncover the mechanism of apoptotic cell clearance by a conserved signaling system (2016) (0)
- PurifiedPlasma Membranes Inhibit PolypeptideGrowth Factor-inducedDNA Synthesis inSubconfluent 3T3 Cells (2007) (0)
- Abstract B101: Mechanism of T cell activation by phase separation (2016) (0)
- Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. (2023) (0)
- Regulation of motor proteins by tubulin carboxy-terminal tails. (2013) (0)
- Chlamydomonas reinhardtii radial spoke head and neck (recombinant) (2020) (0)
- The Lasker Awards: motors take centre stage (2012) (0)
- NCBS SYMPOSIUM ON MOLECULES, MACHINES AND NETWORKS (2003) (0)
- Iodination In 1973, Herrup and Shooter 7 prepared an iodinated derivative of NGF using a lactoperoxidase labeling technique (2003) (0)
- Abstract PR15: Engineering phagocytic signaling (2016) (0)
- Chapter 8 Motile Properties of Cytoplasmic Dynein (2012) (0)
- Alteration of Binding Properties and Cytoskeletal Attachment of Nerve Growth in PC12 Cells by Wheat Germ Agglutinin Factor Receptors (2007) (0)
- Getting a Grip on Myosin Review (1994) (0)
- Directiondetermination in theminus-end-directed kinesinmotor ncd (0)
- Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes (2018) (0)
- Clustering of a kinesin-14 motor enables processive retrograde microtubule-based transport in plants. (2015) (0)
- 1 KINESIN-73 IS A PROCESSIVE MOTOR THAT LOCALIZES TO RAB 5-CONTAINING ORGANELLES (2010) (0)
- Cellular reconstitution of apoptotic cell clearance reveals a multi-step phosphorylation mechanism for Draper receptor triggering (2017) (0)
- RNA Gelation in Repeat Expansion Disorders (2017) (0)
- Crystal and EM Structures Reveal a Mechanism for Long-Range Allosteric Communication in the Yeast Dynein Motor Domain (2014) (0)
- 620a Wednesday, February 24, 2010 Symposium 18: Calcium Flickers and Motility at the Leading Edge Membrane (0)
- Flanking sequences regulate the toxicity, non-ATG translation, and aggregation of RNA with tandem CAG Repeats (2021) (0)
- Homology-Based Model of the Dynein Coiled-Coil Stalk in the 19:19 Configuration. (2005) (0)
- Mechanisms of Dynein-Driven Microtubule Sliding and Cargo Transport (2014) (0)
- A New Method (Sigma-SHREC) for Two-Color Fluorescent Distance Measurements with Nanometer Accuracy (2018) (0)
- Testing kinesin walking models using single molecule FRET analysis (2004) (0)
- Staying on Track : Common Minireview Features of DNA Helicases and Microtubule Motors (1998) (0)
- Gohta Goshima S 2 Cells Drosophila Genes Required for Mitotic Spindle Assembly in (2014) (0)
- Cell ' s Motor Is a Mountain Climber , Not an Inchworm (2006) (0)
- 1SB05 Observation of conformational changes of kinesin walking along microtubules using single molecule FRET technique (2004) (0)
- Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating (2020) (0)
- The cytoplasmic dynein transport machinery and its many cargoes (2018) (0)
- Mechanism and Regulation of Cytoplasmic Dynein (2010) (0)
- Why I do science (2013) (0)
- iBioChina and iBiology: spreading scientific knowledge together (2015) (0)
- “Cortical” Dynein Can Capture And Pull On Dynamic Microtubule Ends In Vitro (2009) (0)
- Author response: Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis (2021) (0)
- Why I Do Science, Part II (2013) (0)
- 1P250 Spatial Organization of Cell Membrane Regulates Signal Transduction(Biol & Artifi memb.:Signal transduction,The 48th Annual Meeting of the Biophysical Society of Japan) (2010) (0)
- Crystal Structure of the Human EB1 C-terminal Dimerization Domain (2005) (0)
- Homology-Based Model of the Dynein Coiled-Coil Stalk in the 22:19 Configuration. (2005) (0)
- Author response: Priority of discovery in the life sciences (2016) (0)
- Ian Read Gibbons. 30 October 1931—30 January 2018 (2019) (0)
- Supplementary Materials for Interdisciplinary Graduate Training in Teaching Labs (2012) (0)
- Corrections and Retraction (2004) (0)
- iBioChina and iBiology: spreading scientific knowledge together (2015) (0)
- Collective Motions and Dynamical Couplings in the Kinesin Motor Domain (2014) (0)
- Determinants of Myosin II Co (2010) (0)
- Crystal Structure of the Dynein Light Intermediate Chain's Conserved Domain (2014) (0)
- Multiplex Regulation of Cytoplasmic Dynein Motility (2015) (0)
- The Art and Science of Cell Biology (ASCB 2 ) (2012) (0)
- Cryo-Electron Tomography of Dynein in vitro and in situ (2007) (0)
- Publish peer reviews (2018) (0)
- Single Molecule Imaging in Living Cells by Total Internal Reflection Fluorescence Microscopy (2006) (0)
- NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER (1999) (0)
- Effect of changing the length of the neck linker on the processive movement of kinesin (2003) (0)
- Summer at the Marine Biological Laboratory (2013) (0)
- Mapping the regulatory landscape of membraneless organelle assembly and dynamics (2022) (0)
- The Kinesin-1 Gating Mechanism Studied by Pre-Steady State Kinetics (2014) (0)
- 1O1400 Dimerization triggers fast, processive movement of Unc104/KIF1A "monomeric" kinesin along microtubules (2002) (0)
- BicD2 and Dynactin Convert a Non-Processive Cytoplasmic Dynein to an Ultra-Processive Directional Motor (2014) (0)
- Coupling between lipid miscibility and phosphotyrosine driven protein condensation at the membrane (2020) (0)
- MODEL OF THE MICROTUBULE MOTOR, NCD, WITH SWITCH 1 CLOSED AND THE ELECTRON PARAMAGNETIC RESONANCE (EPR) SPIN PROBE SSL-NANDP BOUND AT THE NUCLEOTIDE SITE (2004) (0)
- Title Altered actin centripetal retrograde flow in physically restrictedimmunological synapses (2010) (0)
- Purification par affinite de proteines a l'aide d'une fluoresceine bis-arsenicale modifiee (2001) (0)
- Crystal structure of human Hook3's conserved Hook domain (2016) (0)
- 2P171 Strain-dependent regulation of the kinesin-1's catalytic activity as studied by disulfide-crosslinking of the neck linker(11. Molecular motor,Poster) (2013) (0)
- Chlamydomonas reinhardtii radial spoke minimal head complex (2020) (0)
- Introduction Total Internal Reflection Fluorescence Microscopy (2015) (0)
- How Dynein Moves Along (2016) (0)
- MODEL OF THE MICROTUBULE MOTOR, NCD, WITH SWITCH 1 CLOSED AND WITH ADP BOUND AT THE NUCLEOTIDE SITE (2004) (0)
- Differential LAT Microcluster Composition and ACTIN-Dependent Movement at the Immunological Synapse Center (2018) (0)
- Micro-Magellan: A flexible, open source acquisition software for high throughput biological light microscopy (2016) (0)
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