Rony Seger
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Computer Science
Rony Seger's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Rony Seger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The MAPK signaling cascade (1995) (3670)
- The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions (2006) (1271)
- The MEK/ERK cascade: from signaling specificity to diverse functions. (2007) (891)
- Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. (1996) (817)
- The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. (2011) (746)
- ErbB‐2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. (1996) (697)
- The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions. (2010) (513)
- Vimentin-Dependent Spatial Translocation of an Activated MAP Kinase in Injured Nerve (2005) (511)
- Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis (2002) (465)
- Selective requirement for MAP kinase activation in thymocyte differentiation (1995) (445)
- The ERK Cascade: Distinct Functions within Various Subcellular Organelles. (2011) (436)
- Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. (1991) (387)
- In situ activation pattern of Drosophila EGF receptor pathway during development. (1997) (385)
- Association of mitogen-activated protein kinase with the microtubule cytoskeleton. (1995) (380)
- Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53 (2001) (370)
- Activation of MAPK Cascades by G-protein-coupled Receptors: The Case of Gonadotropin-releasing Hormone Receptor (2000) (347)
- DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. (2007) (331)
- Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. (1995) (326)
- MAP kinase in situ activation atlas during Drosophila embryogenesis. (1997) (325)
- Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. (1992) (318)
- Specific and Differential Activation of Mitogen-Activated Protein Kinase Cascades by Unfamiliar Taste in the Insular Cortex of the Behaving Rat (1998) (289)
- Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. (2007) (289)
- Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. (1991) (271)
- Identification and characterization of a general nuclear translocation signal in signaling proteins. (2008) (258)
- The mitogen-activated protein kinase activator. (1992) (256)
- The ERK Signaling Cascade Inhibits Gonadotropin-stimulated Steroidogenesis* (2001) (231)
- Inactivation of Glycogen Synthase Kinase-3 by Epidermal Growth Factor Is Mediated by Mitogen-activated Protein Kinase/p90 Ribosomal Protein S6 Kinase Signaling Pathway in NIH/3T3 Cells (*) (1995) (219)
- Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. (1994) (218)
- Phosphorylation of Insulin Receptor Substrate-1 (IRS-1) by Protein Kinase B Positively Regulates IRS-1 Function* (1999) (208)
- Fibroblast Growth Factor Promotes Recruitment of Skeletal Muscle Satellite Cells in Young and Old Rats (1999) (207)
- Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation. (1997) (196)
- Regulation of p53 (2002) (190)
- Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts. (1999) (189)
- Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. (2001) (184)
- Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation. (1998) (179)
- Interaction with MEK Causes Nuclear Export and Downregulation of Peroxisome Proliferator-Activated Receptor γ (2006) (177)
- The ERK cascade as a prototype of MAPK signaling pathways. (2004) (176)
- Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases. (1992) (173)
- Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase. (2006) (161)
- Regulation of p53: intricate loops and delicate balances. (2002) (156)
- The MAP kinase cascade. (1995) (153)
- CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions (2011) (151)
- ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network (1998) (146)
- Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation (2000) (143)
- Identification of a Cytoplasmic-Retention Sequence in ERK2* (1999) (138)
- Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34+ progenitor cells (2005) (138)
- Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia. (1998) (137)
- Detection of ERK activation by a novel monoclonal antibody (1997) (137)
- MAPK- Kinases as Nucleo-Cytoplasmic Shuttles for PPARγ (2007) (130)
- Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary alpha T3-1 cell line is mediated by protein kinase C, c-Src, and CDC42. (1998) (128)
- Activation of MAPK Cascades by GnRH: ERK and Jun N-Terminal Kinase Are Involved in Basal and GnRH-Stimulated Activity of the Glycoprotein Hormone LHβ-Subunit Promoter. (2002) (128)
- Interactions of β and γENaC with Nedd4 Can Be Facilitated by an ERK-mediated Phosphorylation* (2002) (123)
- Mechanism of Mitogen-Activated Protein Kinase Activation by Gonadotropin-Releasing Hormone in the Pituitary αT3-1 Cell Line: Differential Roles of Calcium and Protein Kinase C. (1997) (123)
- The ERK signaling cascade—Views from different subcellular compartments (2009) (122)
- Protein-protein interactions in the regulation of the extracellular signal-regulated kinase (2005) (121)
- Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells (2007) (118)
- The subcellular localization of MEK and ERK—A novel nuclear translocation signal (NTS) paves a way to the nucleus (2010) (115)
- The C‐terminus of the kinase‐defective neuregulin receptor ErbB‐3 confers mitogenic superiority and dictates endocytic routing (1999) (112)
- Nuclear ERK: Mechanism of Translocation, Substrates, and Role in Cancer (2019) (110)
- Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. (2005) (105)
- BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors (2010) (104)
- ERK1c regulates Golgi fragmentation during mitosis (2006) (104)
- Down-regulation of steroidogenic response to gonadotropins in human and rat preovulatory granulosa cells involves mitogen-activated protein kinase activation and modulation of DAX-1 and steroidogenic factor-1. (2003) (97)
- Identification of Extracellular Signal-regulated Kinase 1/2 and p38 MAPK as Regulators of Human Sperm Motility and Acrosome Reaction and as Predictors of Poor Spermatozoan Quality* (2008) (96)
- The nuclear translocation of ERK1/2 as an anticancer target (2015) (95)
- Neu Differentiation Factor Stimulates Phosphorylation and Activation of the Sp1 Transcription Factor (1999) (94)
- Extracellular Signal-Regulated Kinase, Jun N-Terminal Kinase, p38, and c-Src Are Involved in Gonadotropin-Releasing Hormone-Stimulated Activity of the Glycoprotein Hormone Follicle-Stimulating Hormone β-Subunit Promoter (2004) (92)
- Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms (1998) (91)
- Co‐stimulation‐dependent activation of a JNK‐kinase in T lymphocytes (1998) (91)
- The dynamic subcellular localization of ERK: mechanisms of translocation and role in various organelles. (2016) (85)
- Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by Autophosphorylation (2011) (82)
- A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation. (2004) (82)
- Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells (2014) (82)
- PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation. (2006) (82)
- Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer (2003) (81)
- Calcium regulates ERK signaling by modulating its protein-protein interactions (2008) (76)
- Involvement of the ERK mitogen‐activated protein kinase in cell resistance to complement‐mediated lysis (2001) (70)
- Mechanisms of gonadotropin desensitization (2002) (69)
- Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation. (2002) (67)
- Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function (2004) (65)
- The Requirement of Both Extracellular Regulated Kinase and p38 Mitogen-activated Protein Kinase for Stimulation of Cytosolic Phospholipase A2 Activity by Either FcγRIIA or FcγRIIIB in Human Neutrophils (2000) (64)
- The ERK cascade inhibitors: Towards overcoming resistance. (2016) (63)
- MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation (2004) (63)
- c-Src Is Activated by the Epidermal Growth Factor Receptor in a Pathway That Mediates JNK and ERK Activation by Gonadotropin-releasing Hormone in COS7 Cells* (2003) (63)
- Regulation of p53: intricate loops and delicate balances. (2002) (62)
- Role of Dynamin, Src, and Ras in the Protein Kinase C-mediated Activation of ERK by Gonadotropin-releasing Hormone* (2001) (62)
- BMP-4 regulates the dorsal-ventral differences in FGF/MAPKK-mediated mesoderm induction in Xenopus. (1995) (61)
- LIS1 is a microtubule-associated phosphoprotein. (1999) (61)
- Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement. (1995) (60)
- CPG16, a Novel Protein Serine/Threonine Kinase Downstream of cAMP-dependent Protein Kinase* (1999) (60)
- ERK1b, a 46-kDa ERK Isoform That Is Differentially Regulated by MEK* (2000) (59)
- Gonadotropin-Releasing Hormone Induces Apoptosis of Prostate Cancer Cells (2004) (58)
- Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor. (2005) (57)
- Mechanism of GnRH receptor signaling on gonadotropin release and gene expression in pituitary gonadotrophs. (2001) (56)
- Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells. (1993) (55)
- Lipid constituents in oligodendroglial cells alter susceptibility to H2O2‐induced apoptotic cell death via ERK activation (2001) (55)
- Identification of an Activator of the Microtubule‐Associated Protein 2 Kinases ERK1 and ERK2 in PC12 Cells Stimulated with Nerve Growth Factor or Bradykinin (1992) (54)
- Gonadotropin-releasing hormone in apoptosis of prostate cancer cells. (2006) (52)
- ERK as a Model for Systems Biology of Enzyme Kinetics in Cells (2013) (52)
- Differential Activation of Mitogen-activated Protein Kinase and S6 Kinase Signaling Pathways by 12-O-Tetradecanoylphorbol-13-acetate (TPA) and Insulin (1995) (52)
- Hyperglycemia reduces nitric oxide synthase and glycogen synthase activity in endothelial cells. (2002) (52)
- PPARγ and MEK Interactions in Cancer (2008) (52)
- Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. (2009) (50)
- Involvement of the Activation Loop of ERK in the Detachment from Cytosolic Anchoring* (2001) (50)
- The MAPK Signaling Cascades (2016) (50)
- The CK2 Phosphorylation of Vitronectin (2001) (50)
- The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis (2005) (50)
- Non-regulated and stimulated mechanisms cooperate in the nuclear accumulation of MEK1 (2001) (49)
- Extracellular Signal-Regulated Kinase and c-Src, But Not Jun N-Terminal Kinase, Are Involved in Basal and Gonadotropin-Releasing Hormone-Stimulated Activity of the Glycoprotein Hormone α-Subunit Promoter (2003) (49)
- Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation process. (1994) (49)
- Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases (2000) (48)
- Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments (2015) (48)
- Analysis of signal transduction stimulated by gonadotropins in granulosa cells (2003) (47)
- Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits. (2002) (47)
- Altered Regulation of ERK1b by MEK1 and PTP-SL and Modified Elk1 Phosphorylation by ERK1b Are Caused by Abrogation of the Regulatory C-terminal Sequence of ERKs* (2001) (45)
- Maturation-Promoting Factor Governs Mitogen-Activated Protein Kinase Activation and Interphase Suppression During Meiosis of Rat Oocytes1 (2003) (45)
- The Nuclear Translocation of Mitogen-Activated Protein Kinases: Molecular Mechanisms and Use as Novel Therapeutic Target (2018) (42)
- The Ras Inhibitors Caveolin-1 and Docking Protein 1 Activate Peroxisome Proliferator-Activated Receptor γ through Spatial Relocalization at Helix 7 of Its Ligand-Binding Domain (2011) (42)
- The Cytoskeletal Network Controls c-Jun Expression and Glucocorticoid Receptor Transcriptional Activity in an Antagonistic and Cell-Type-Specific Manner (1999) (41)
- Cutting Edge: Extracellular Signal-Regulated Kinase Activates Syk: A New Potential Feedback Regulation of Fcε Receptor Signaling (1999) (40)
- A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells. (2009) (39)
- A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa (2016) (39)
- Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (2010) (38)
- In vitro phosphorylation of COOH termini of the epithelial Na(+) channel and its effects on channel activity in Xenopus oocytes. (2001) (37)
- Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species (2005) (37)
- Beta-Like Importins Mediate the Nuclear Translocation of Mitogen-Activated Protein Kinases (2013) (35)
- Stimulated nuclear import by β-like importins (2013) (35)
- Mechanism of GnRH receptor signaling: from the membrane to the nucleus. (1999) (33)
- Ras‐Signaling Pathways: Positive and Negative Regulation of Tau Expression in PC12 Cells (1998) (32)
- ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage (2002) (32)
- Gi-mediated activation of mitogen-activated protein kinase (MAPK) pathway by receptor mimetic basic secretagogues of connective tissue-type mast cells: bifurcation of arachidonic acid-induced release upstream of MAPK. (1999) (32)
- Calcium-mediated Interactions Regulate the Subcellular Localization of Extracellular Signal-regulated Kinases* (2008) (31)
- Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter. (2002) (31)
- Extremely low‐frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium (2016) (31)
- The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer (2018) (29)
- Variable phosphorylation states of pigment-epithelium-derived factor differentially regulate its function. (2006) (29)
- Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues. (1993) (28)
- Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary of alphaT3-1 cell line: differential roles of calcium and protein kinase C. (1997) (27)
- Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis (2017) (27)
- Growth factor-stimulated phosphorylation cascades: activation of growth factor-stimulated MAP kinase. (1992) (26)
- The Nuclear Translocation of ERK. (2017) (25)
- Identification of an inducible 85-kDa nuclear protein kinase. (1993) (25)
- BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors (2010) (24)
- Signal transduction of the gonadotropin releasing hormone (GnRH) receptor: Cross-talk of calcium, protein kinase C (PKC), and arachidonic acid (1995) (24)
- Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter. (2004) (23)
- Nuclear P38: Roles in Physiological and Pathological Processes and Regulation of Nuclear Translocation (2020) (22)
- Distinct pathways for the involvement of WNK4 in the signaling of hypertonicity and EGF (2008) (22)
- Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases (2018) (22)
- The CK2 phosphorylation of vitronectin. Promotion of cell adhesion via the alpha(v)beta 3-phosphatidylinositol 3-kinase pathway. (2001) (22)
- Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase. (2010) (22)
- GRFβ, a Novel Regulator of Calcium Signaling, Is Expressed in Pancreatic Beta Cells and Brain* (1999) (21)
- Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields (2017) (21)
- High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry (2017) (19)
- Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (2017) (19)
- Calcium Regulation of EGF-Induced ERK5 Activation: Role of Lad1-MEKK2 Interaction (2010) (19)
- The Role of ERK Signaling in Experimental Autoimmune Encephalomyelitis (2017) (18)
- A PARP1-ERK2 synergism is required for the induction of LTP (2016) (18)
- Nuclear ERK Translocation is Mediated by Protein Kinase CK2 and Accelerated by Autophosphorylation. (2011) (18)
- The Requirement of Both Extracellular Regulated Kinase and p38 Mitogen-activated Protein Kinase for Stimulation of Cytosolic Phospholipase A2 Activity by Either FcgRIIA or FcgRIIIB in Human Neutrophils A POSSIBLE ROLE FOR Pyk2 BUT NOT FOR THE Grb2-Sos-Shc COMPLEX* (2000) (17)
- Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer (2016) (16)
- Role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH in the pituitary gonadotropes (2015) (15)
- The mitogen-activated protein kinase signaling cascade: from bench to bedside. (2002) (15)
- The epidermal growth factor receptor as a substrate for a kinase-splitting membranal proteinase. (1988) (15)
- Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation. (2008) (14)
- Differential signaling of the GnRH receptor in pituitary gonadotrope cell lines and prostate cancer cell lines (2013) (14)
- Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ–14-3-3γ shuttling complex (2015) (14)
- Mxi2 sustains ERK1/2 phosphorylation in the nucleus by preventing ERK1/2 binding to phosphatases. (2012) (14)
- Nuclear localization of phosphorylated ERK1 and ERK2 as markers for the progression of ovarian cancer. (2011) (13)
- Gq Protein-induced Apoptosis Is Mediated by AKT Kinase Inhibition That Leads to Protein Kinase C-induced c-Jun N-terminal Kinase Activation* (2011) (13)
- Cutting edge: extracellular signal-regulated kinase activates syk: a new potential feedback regulation of Fc epsilon receptor signaling. (1999) (13)
- Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (2017) (12)
- Receptor tyrosine kinases: the emerging tip of systems control. (2008) (11)
- Involvement of the activation loop of ERK in the detachment from cytosolic anchoring. (2017) (11)
- Beta-Like Importins Mediate the Nuclear Translocation of MAPKs. (2019) (10)
- Activation of a 74 kDa plasma membrane protein kinase by hyperosmotic shocks in the halotolerant alga Dunaliella salina (1997) (10)
- Pigment Epithelium-derived Factor and Its Phosphomimetic Mutant Induce JNK-dependent Apoptosis and p38-mediated Migration Arrest* (2010) (10)
- Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter. (2003) (10)
- Communication between protein tyrosine and protein serine/threonine phosphorylation. (1990) (10)
- Determination of ERK activity: anti-phospho-ERK antibodies and in vitro phosphorylation. (2010) (9)
- Induction of intracellular signalling by cyclic glycerophosphates and their deoxy analogues. (2000) (9)
- Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation (2018) (9)
- The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis. (2017) (9)
- ERK Signaling in Colorectal Cancer: A Preliminary Report on the Expression of Phosphorylated ERK and the Effects of Radiation Therapy (2008) (9)
- Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone. (2017) (9)
- Role of Non-phosphorylated Activation Loop Residues in Determining ERK2 Dephosphorylation, Activity, and Subcellular Localization* (2007) (9)
- Alternative Splicing of MAPKs in the Regulation of Signaling Specificity (2021) (9)
- Faculty Opinions recommendation of G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR). (2010) (8)
- Deletion of Alloreactive T Cells by Veto Cytotoxic T Lymphocytes Is Mediated Through Extracellular Signal-Regulated Kinase Phosphorylation (2010) (8)
- A 50-kDa ERK-like protein is up-regulated by a dual altered peptide ligand that suppresses myasthenia gravis-associated responses (2006) (8)
- Differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells (2017) (8)
- ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network (1998) (8)
- Activation of MAP kinases, cPLA2 and reactive oxygen species formation by EGF and calcium mobilizing agonists in a human keratinocyte cell line. (1997) (8)
- Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. (2008) (8)
- The Detection of MAPK Signaling (2006) (7)
- Membrane-permeable tastants amplify β2-adrenergic receptor signaling and delay receptor desensitization via intracellular inhibition of GRK2's kinase activity. (2015) (7)
- Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentation (2021) (7)
- Dynamic distribution of ERK, p38 and JNK during the development of pancreatic ductal adenocarcinoma. (2014) (7)
- GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs (2017) (7)
- Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest (2018) (6)
- MAP Kinase Signaling Protocols (2004) (6)
- Infectious inflammation of the CNS involves activation of mitogen-activated protein kinase and AKT proteins in CSF in humans (2005) (6)
- Studying the structure of the intracellular moiety of the insulin receptor with a kinase‐splitting membranal proteinase. (1989) (5)
- Use of inhibitors in the study of MAPK signaling. (2004) (5)
- Ligand interaction scan (LIScan) in the study of ERK8. (2010) (5)
- SB203580 Induces Prolonged B-Raf Activation and Promotes Neuronal Differentiation upon EGF Treatment of PC12 Cells (2004) (5)
- Calcium-Mediated Interactions Regulate the Subcellular Localization of Extracellular Signal-Regulated Kinases (ERKs). (2020) (5)
- Two initiation sites of early detection of colon cancer, revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of tumor cells. (2011) (5)
- C-Src Is Activated by the EGF Receptor in a Pathway that Mediates JNK and ERK Activation by Gonadotropin-Releasing Hormone in COS7 Cells (2020) (5)
- The Detection of MAPK Signaling (2005) (5)
- ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK. (2017) (5)
- RAF, MEK and ERK Inhibitors as Anti-Cancer Drugs: Intrinsic and Acquired Resistance as a Major Therapeutic Challenge (2018) (4)
- ECTO- AND EXO-PROTEIN KINASES IN SCHISTOSOMA MANSONI: REGULATION OF SURFACE PHOSPHORYLATION BY ACETYLCHOLINE AND IDENTIFICATION OF THE ALPHA SUBUNIT OF CKII AS A MAJOR SECRETED PROTEIN KINASE (2005) (4)
- Green Tea Cancer Prevention (2011) (4)
- Leptomycin B : An Important Tool for the Study of Nuclear Export (3)
- Determination of ERK Activity (2004) (3)
- The extra-cellular signal regulated kinases ERK1 and ERK2 segregate displaying distinct spatiotemporal characteristics in activated mast cells. (2013) (3)
- Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors. (2022) (3)
- GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch (2022) (3)
- c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. (2017) (3)
- Determination of ERK activity: antiphospho-ERK antibodies, in vitro phosphorylation, and in-gel kinase assay. (2004) (3)
- Detection of MAP Kinase Signaling (1998) (2)
- Regulation of protein serine/threonine kinases by tyrosine kinases. (1993) (2)
- Two initiation sites of early detection of colon cancer revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of the tumor cells. (2013) (2)
- Activation of the AMPK regulated metabolic stress response by a small molecule HER2/EGFR tyrosine kinase inhibitor protects cardiac myocytes from apoptotic stimuli (2007) (2)
- ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network (1999) (2)
- Nuclear targeting sequences (1992) (2)
- Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma (2020) (2)
- Erratum: Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues (Proc. Natl. Acad. Sci. USA (June 1, 1993) 90 (5143-5147)) (1993) (2)
- Fibroblast growth factor ( FGF ) signaling through PI 3-kinase and Akt / PKB is required for embryoid body di erentiation (2000) (1)
- Corrigendum to differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells. [Mol Cell Endocrinol 439: 141–154 (2017)] (2019) (1)
- Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. (2017) (1)
- Retraction notice to "Regulation of p53: Intricate loops and delicate balances" [Biochem. Pharmacol. 64 (2002) 865-871]. (2015) (1)
- of Enzyme Kinetics in Cells ReviewERK as a Model for Systems Biology (2013) (1)
- Faculty Opinions recommendation of REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling. (2014) (1)
- Faculty of 1000 evaluation for Molecular mechanism of the nuclear protein import cycle. (2013) (1)
- The Role of ERK5 Signaling in Tolerance Induction by Veto CTLs. (2005) (1)
- Nucleoporin-93 overexpression overcomes multiple nucleocytoplsamic trafficking bottlenecks to permit robust metastasis (2020) (1)
- Protein phosphorylation is modulated in fetal brain preparations after episodes of ischemia (1997) (1)
- Inhibition of gonadotropin-stimulated steroidogenesis by the erk cascade (2019) (1)
- Faculty Opinions recommendation of Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3. (2013) (1)
- Immunological Detection of Phosphorylation (1998) (1)
- Retention of ERK in the cytoplasm mediates the pluripotency of embryonic stem cells (2022) (1)
- AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope. (2022) (1)
- Construction of nucleosome cores from defined DNA sequences of prokaryotic origin. (1992) (1)
- Faculty Opinions recommendation of Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation. (2011) (1)
- Abstracts of the 15th Annual Meeting of the Israel Society for Neuroscience Eilat, Israel, December 3–5, 2006 (2006) (1)
- Faculty Opinions recommendation of MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1. (2015) (0)
- Faculty Opinions recommendation of MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. (2009) (0)
- Faculty of 1000 evaluation for Nuclear import by karyopherin-βs: recognition and inhibition. (2013) (0)
- Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (2019) (0)
- Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs. (2017) (0)
- Faculty Opinions recommendation of PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. (2012) (0)
- Faculty Opinions recommendation of The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. (2015) (0)
- The Roles of Specific Residues on ERK2 for Nuclear Translocation in Response to Nerve Growth Factors in PC12 Cells (2004) (0)
- Correction for Aebersold et al., “Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function” (2017) (0)
- Faculty Opinions recommendation of The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress. (2013) (0)
- Secreted Spitz trig.gers the DER signaling pathway and is a hmltmg component m embryonic ventral ectoderm determination (2007) (0)
- Faculty of 1000 evaluation for Nucleocytoplasmic shuttling of signal transducers. (2013) (0)
- Abstracts of the 16th Annual Meeting of The Israel Society for Neuroscience Eilat, Israel, November 25–27, 2007 (2008) (0)
- Targeting the nuclear translocation of MAPKs as a novel anti-inflammatory and anti-cancer therapy (2016) (0)
- Faculty Opinions recommendation of Cloning and characterization of human karyopherin beta3. (2013) (0)
- The extracellular signal regulated kinases ERK 1 and ERK 2 segregate displaying distinct spatiotemporal characteristics in activatedmast cells (2013) (0)
- High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry (2017) (0)
- Faculty Opinions recommendation of Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. (2011) (0)
- β‐like Importins mediate the nuclear translocation of JNK1/2 and p38α/β (LB219) (2014) (0)
- Room F, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Activation of Mitogen-Activated Protein Kinase Signalling Following Traumatic Brain Injury in Rats A-712 (2000) (0)
- Table of Contents (1996) (0)
- Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (2019) (0)
- The Mitogen-activated Protein Kinase Kinase 3 (0)
- Faculty Opinions recommendation of Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex. (2015) (0)
- Retraction for Plotnikov et al., “Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by Autophosphorylation” (2018) (0)
- Gonadotropin releasing hormone (2000) (0)
- Faculty Opinions recommendation of ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes. (2010) (0)
- Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells (2017) (0)
- Nuclear translocation mechanism of ERK2 in response to NGF stimulation in PC 12 cells (2001) (0)
- FGF signaling in head muscle development (2012) (0)
- Nucleoporin-93 Overcomes Multiple Nucleocytoplasmic Trafficking Bottlenecks and Permits Robust Metastasis (2021) (0)
- 323 Targeted use of combination of erbB targeted therapy (2004) (0)
- The ERK Signaling Cascade Inhibits Gonadotropin-Stimulated Steroidogenesis (2023) (0)
- Faculty Opinions recommendation of Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7. (2013) (0)
- Functional SDF-1 Secretion from BM Stromal Cells Is a Cell Contact-Dependent Event Mediated by Cx43 and Cx45 Gap-Junctions (2008) (0)
- ERK1b, a 46‐kDa ERK isoform that is differentially regulated by MEK (2022) (0)
- Faculty Opinions recommendation of A distinct nuclear import pathway used by ribosomal proteins. (2013) (0)
- Growth Guidance Cue (2011) (0)
- Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases (2018) (0)
- A Kinase Splitting Membranal Proteinase: Use in the Study of Receptors Involved in the Cellular Response to Hormones (1988) (0)
- Faculty of 1000 evaluation for ERK dimers and scaffold proteins: unexpected partners for a forgotten (cytoplasmic) task. (2013) (0)
- Faculty Opinions recommendation of Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7. (2013) (0)
- Correction for Zehorai and Seger, “Beta-Like Importins Mediate the Nuclear Translocation of Mitogen-Activated Protein Kinases” (2017) (0)
- Early infiltration of innate immune cells to the liver depletes HNF4a and promotes extra-hepatic carcinogenesis. (2023) (0)
- P-832 : Prostaglandin E2 (PGE2) up regulates epidermal growth factor- like factors biosynthesis in human granulosa cells: New insights of the coordination between PGE2 and luteinizing hormone in ovulation (2006) (0)
- Faculty Opinions recommendation of Cell fate decisions are specified by the dynamic ERK interactome. (2009) (0)
- Applying imaging flow cytometry and immunofluorescence in studying the dynamic Golgi structure in cultured cells (2022) (0)
- Faculty Opinions recommendation of PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. (2013) (0)
- Faculty Opinions recommendation of Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation. (2013) (0)
- Taste experience activates MAP kinase in the rat insular cortex (1997) (0)
- Nuclear P38 | Encyclopedia (2020) (0)
- Faculty Opinions recommendation of The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. (2013) (0)
- GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch (2022) (0)
- Faculty Opinions recommendation of Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. (2013) (0)
- Calcium is involved in EGF‐induced activation of ERK5 by mediating Lad‐MEKK2 interaction. (2006) (0)
- Faculty Opinions recommendation of Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. (2010) (0)
- The Role of ERK and XIAP in Tolerance Induction by Veto CTLs. (2007) (0)
- ReviewArticle PPARγ and MEK Interactions in Cancer (2008) (0)
- Faculty Opinions recommendation of Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily. (2013) (0)
- Detection of MAP Kinase Signaling (2004) (0)
- Apoptosis related signaling in the reproductive system (2008) (0)
- The Biochemistry, Biology and Pathology of MAP Kinases II, 10-11 September 2014, Vilnius - Lithuania (2014) (0)
- Retraction for Zehorai and Seger, “Beta-Like Importins Mediate the Nuclear Translocation of Mitogen-Activated Protein Kinases” (2018) (0)
- Combination therapy for the treatment of cancer (2017) (0)
- Faculty Opinions recommendation of Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development. (2015) (0)
- The Use of Combination erbB Targeted Therapies (2004) (0)
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What Schools Are Affiliated With Rony Seger?
Rony Seger is affiliated with the following schools:
