Rudi Schmid

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Rudi Schmid is affiliated with the following schools: Stanford University, University of Chicago, University of California, San Francisco, University of Zurich

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Rudi Schmid

Philosophy

#3816

World Rank

#6104

Historical Rank

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#1430

World Rank

#2180

Historical Rank

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Philosophy

Rudi Schmid's Degrees

Doctorate Medicine University of Zurich
PhD Medical Sciences University of Zurich

Why Is Rudi Schmid Influential?

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According to Wikipedia, Rudi Schmid was a Swiss-born American medical researcher specializing in hepatology. Among his contributions to biomedical science, Schmid led a team to discover heme oxygenase. Schmid was born on 2 May 1922 to physician parents. He was born and raised in Glarus, which inspired his interest in mountain climbing. Schmid became a skilled alpinist and skier. Schmid was a member of the Swiss national ski team from 1941 to 1945, and led the Academic Alpine Club while studying at the University of Zurich. In 1946, while still at university, Schmid became one of the first climbers to ascend Mont Blanc via its west face.

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Rudi Schmid's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. (1968) (1696)
Microsomal heme oxygenase. Characterization of the enzyme. (1969) (1185)
The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin. (1970) (373)
The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro. (1961) (365)
Chronic progressive myopathy with myoglobinuria: demonstration of a glycogenolytic defect in the muscle. (1959) (283)
Reduced nicotinamide-adenine dinucleotide phosphate dependent biliverdin reductase: partial purification and characterization. (1970) (234)
Experimental bilirubin encephalopathy. The mode of entry of bilirubin-14C into the central nervous system. (1966) (222)
Congenital jaundice in rats, due to a defect in glucuronide formation. (1958) (218)
Intestinal absorption of hemoglobin iron-heme cleavage by mucosal heme oxygenase. (1974) (214)
Acquired Porphyria in Man and Rat due to Hexachlorobenzene Intoxication (1961) (209)
METABOLISM AND DISPOSITION OF C14-BILIRUBIN IN CONGENITAL NONHEMOLYTIC JAUNDICE. (1963) (201)
Cutaneous porphyria in Turkey. (1960) (200)
Direct-reacting bilirubin, bilirubin glucuronide, in serum, bile and urine. (1956) (189)
Porphyrin content of bone marrow and liver in the various forms of porphyria. (1954) (179)
The preparation of crystalline bilirubin-C14. (1961) (169)
Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide. (1970) (164)
GLYCOGEN SYNTHESIS IN MUSCLE LACKING PHOSPHORYLASE. (1959) (149)
Hepatitis B viral DNA in liver and serum of asymptomatic carriers. (1982) (139)
THE PROTEIN-BINDING OF C14-BILIRUBIN IN HUMAN AND MURINE SERUM. (1963) (129)
Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography. (1980) (129)
Metabolic regulation of heme catabolism and bilirubin production. I. Hormonal control of hepatic heme oxygenase activity. (1972) (126)
Intestinal absorption of bile pigments. I. The enterohepatic circulation of bilirubin in the rat. (1963) (125)
Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism. (1971) (123)
The formation of bilirubin from hemoglobin in vivo. (1962) (122)
The identification of direct-reacting bilirubin as bilirubin glucuronide. (1957) (121)
THE ENZYMATIC DEGRADATION OF HEMOGLOBIN TO BILE PIGMENTS BY MACROPHAGES (1971) (119)
Intestinal Absorption of Bile Pigments (1963) (115)
Carbohydrates in pooled dental plaque. (1972) (104)
Hemoglobin and erythrocyte catabolism in rat liver: the separate roles of parenchymal and sinusoidal cells. (1972) (97)
Interaction of Bilirubin with Albumin (1965) (96)
The enzymatic formation of bilirubin glucuronide. (1957) (95)
A Biochemical Lesion in Congenital, Non-obstructive, Non-hæmolytic Jaundice (1957) (93)
Erythropoietic protoporphyria: evidence for multiple sites of excess protoporphyrin formation. (1971) (93)
Powdered Milk Micellar Casein Prevents Oral Colonization by Streptococcus sobrinus and Dental Caries in Rats: A Basis for the Caries–Protective Effect of Dairy Products (1999) (92)
Enhanced formation of rapidly labelled bilirubin by phenobarbital: hepatic microsomal cytochromes as a possible source. (1966) (91)
Hereditary absence of muscle phosphorylase (McArdle's syndrome). (1961) (89)
Oxidative metabolism of foreign compounds in rat small intestine: cellular localization and dependence on dietary iron. (1976) (88)
Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450. (1972) (88)
BILIRUBIN METABOLISM IN THE FETUS. (1964) (87)
LIVER SINUSOIDAL CELLS (1972) (85)
Glucuronide formation in patients with constitutional hepatic dysfunction (Gilbert's disease). (1959) (85)
Approach to the Patient with Cholestatic Jaundice (1983) (83)
Experimental Porphyria. III. Hepatic Type Produced by Sedormid.∗ (1952) (82)
Erythrocyte catabolism by macrophages in vitro. The effect of hydrocortisone on erythrophagocytosis and on the induction of heme oxygenase. (1973) (80)
Cariogenic effects of cooked wheat starch alone or with sucrose and frequency-controlled feedings in rats. (1982) (76)
THE ENZYMATIC FORMATION OF BILIRUBIN * (1975) (74)
The sources of bile pigment in the rat: studies of the "early labeled" fraction. (1966) (70)
Erythropoietic (congenital) porphyria: A rare abnormality of the normoblasts. (1955) (66)
Liver Regeneration in Experimental Carbon Tetrachloride Intoxication.∗ (1959) (65)
The micellar sink: a quantitative assessment of the association of organic anions with mixed micelles and other macromolecular aggregates in rat bile. (1978) (63)
THE CONVERSION OF HEMATIN TO BILE PIGMENT IN THE RAT. (1965) (61)
Oxidative Phosphorylation in Experimental Bilirubin Encephalopathy (1967) (60)
The Enzymatic Formation of Porphobilinogen From δ-Aminolevulinic Acid and Its Conversion To Protoporphyrin1 (1955) (59)
Bilirubin diglucuronide synthesis by a UDP-glucuronic acid-dependent enzyme system in rat liver microsomes. (1979) (58)
Bilirubin kinetics in intact rats and isolated perfused liver. Evidence for hepatic deconjugation of bilirubin glucuronides. (1981) (55)
Cytochrome P-450 and drug metabolism in intestinal villous and crypt cells of rats: effect of dietary iron. (1975) (52)
Heme and methemoglobin: naturally occurring repressors of microsomal cytochrome. (1968) (52)
A new therapeutic approach to unconjugated hyperbilirubinaemia. (1962) (52)
Experimental porphyria. IV. Studies of liver catalase and other heme enzymes in sedormid porphyria. (1955) (50)
Some dental effects of xylitol under laboratory and in vivo conditions. (1977) (48)
In vitro and in vivo studies on triclosan/PVM/MA copolymer/NaF combination as an anti-plaque agent. (1989) (48)
Bilirubin formation in the liver from nonhemoglobin sources. Experiments with isolated, perfused rat liver. (1965) (46)
Effect of ethanol on fatty acid metabolism in liver slices (1959) (45)
Reciprocal relation between plasma albumin level and hepatic sulfobromophthalein removal. (1971) (45)
Intestinal absorption of bile pigments. II. Bilirubin absorption in man. (1963) (45)
5 – Formation and Metabolism of Bile Pigments in Vivo (1979) (44)
Jaundice in thalassemia minor: a consequence of "ineffective erythropoiesis". (1962) (43)
Incorporation of exogenous heme into hepatic cytochrome P-450 in vivo. (1979) (43)
Formation and disposition of newly synthesized heme in adult rat hepatocytes in primary culture. (1981) (43)
Alveolar bone loss in rats after immunization with Actinomyces viscosus (1981) (42)
Effect on caries incidence in rats of increasing dietary sucrose levels. (1979) (41)
The enzymatic conversion of hemoglobin to bilirubin. (1969) (41)
Effect of cobalt on microsomal cytochrome P-450: differences between liver and intestinal mucosa. (1975) (41)
Bilirubin metabolism in man. (1972) (39)
Metabolism and disposition of C14-bilirubin in congenital non-hemolytic jaundice. (1962) (38)
Bile Pigment Excretion in Amphibia (1961) (37)
Solubility of Bilirubin in Aqueous Solutions.∗ (1962) (36)
In vitro development of cat embryos produced by in vitro fertilization is enhanced by addition of cysteine to the maturation medium and a reduced O2 atmosphere (1999) (31)
Hereditary hepatic porphyrias. (1973) (31)
Gilbert's syndrome--a legitimate genetic anomaly? (1995) (27)
Interference with bile pigment uptake in the liver by flavaspidic acid. (1967) (27)
Enterohepatic Circulation of Bilirubin (1961) (27)
Effects of the topical application of mutanase on rat caries. (1980) (26)
Mechanism of bilirubin diglucuronide formation in intact rats: bilirubin diglucuronide formation in vivo. (1980) (25)
Experimental Porphyria. II. Type Produced by Lead, Phenylhydrazine and Light.∗ (1952) (25)
The catabolism of Heinz bodies: an experimental model demonstrating conversion to non-bilirubin catabolites. (1968) (25)
FACTITIOUS diseases: clinical staff conference at the National Institutes of Health. (1958) (25)
Porphyrins in the Bone Marrow and Circulating Erythrocytes in Experimental Anemias.∗ (1950) (25)
Bilirubin Metabolism in the Fœtus (1959) (24)
Neonatal hyperbilirubinemia and kernicterus. Experimental support for treatment by exposure to visible light. (1968) (24)
Viral hepatitis : a contemporary assessment of etiology, epidemiology, pathogenesis, and prevention : proceedings of the Second Symposium on Viral Hepatitis, University of California, San Francisco, March 16-19, 1978 (1978) (24)
Erythrophagocytosis by macrophages: suppression of heme oxygenase by cyclic AMP. (1975) (24)
Cariogenicity of Milchschnitte (Ferrero GmbH) and apple in program-fed rats. (1991) (22)
Effect of the length and number of intervals between meals on caries in rats. (1984) (22)
Excretion of G14-Bilirubin in Newborn Guinea Pigs ∗ (1964) (22)
Some aspects of bile pigment metabolism. (1957) (21)
Effect on rat caries of endogenous and exogenous hydrogen peroxide. (1981) (21)
Effect of topical application of urea peroxide on caries incidence and plaque accumulation in rats. (1982) (20)
History of viral hepatitis: A tale of dogmas and misinterpretations 1 (2001) (20)
Cytochrome P-450 heme moiety. The specific target in drug-induced heme alkylation. (1981) (19)
Fluoride Availability in Human Saliva after Dentifrice Use: Correlation with Anticaries Effects in Rats (1992) (19)
Intermittent acute porphyria: the enzymatic defect. (1974) (19)
Excretion of unconjugated bilirubin in the bile of Gunn rats. (1969) (17)
Experimental Porphyria. I. Isolation of Uroporphyrin I from Bone Marrow of Lead Poisoned Rabbits.∗ (1952) (17)
Biotransformation in the liver: implications for human disease. (1968) (16)
Synthesis and degradation of microsomal hemoproteins. (1973) (16)
Drugs and bilirubin. (1971) (16)
Efficacy of montelukast in the treatment of chronic obstructive pulmonary disease in five horses (2003) (15)
INTESTINAL ABSORPTION OF BILE PIGMENTS. IV. UROBILINOGEN ABSORPTION IN MAN. (1965) (15)
Conjugated Plasma Bilirubin in Jaundice caused by Pigment Overload (1967) (15)
The manifestations of the different forms of porphyria in relation to chemical findings. (1951) (14)
The effect of post-eruptive fluoride uptake and enamel maturation on dental caries in Osborne-Mendel rats. (1965) (14)
LACK OF EFFECT OF CHOLESTYRAMINE RESIN ON HYPERBILIRUBINAEMIA OF PREMATURE INFANTS. (1963) (13)
[Erosion and abrasion of the dental enamel. Experimental study]. (1978) (13)
Hepatic GSH in hexachlorobenzene-induced porphyria☆ (1962) (13)
The effect of titanium, aluminum and fluoride on rat caries. (1974) (12)
Stimulation of hepatic fatty acid synthesis by ethanol. (1961) (12)
More light on neonatal hyperbilirubinemia? (1971) (12)
Caries and plaque inhibition in rats by five topically applied dentifrices. (1997) (12)
BILIRUBIN METABOLISM. (1964) (11)
Effects of follicular fluid or progesterone on in vitro maturation of equine oocytes before intracytoplasmic sperm injection with non-sorted and sex-sorted spermatozoa. (2000) (11)
Exogenous heme restores in vivo functional capacity of hepatic cytochrome P-450 destroyed by allylisopropylacetamide. (1979) (10)
Heme enhances hexobarbital metabolism in perfused rat liver after drug-mediated destruction of cytochrome P-450. (1981) (10)
CHAPTER 8 – Implication of Conjugation of Endogenous Compounds—Bilirubin (1966) (10)
Ischemic disease of the colon and oral contraceptives. (1977) (10)
HEPATOXIC DRUGS CAUSING PORPHYRIA IN MAN AND ANIMALS. (1963) (10)
Enterohepatic Circulation of Urobilinogen (1964) (10)
Jaundice and bilirubin metabolism. (1958) (9)
Efflux of Bilirubin into Plasma following Hepatic Degradation of Exogenous Heme 1 2 (1980) (8)
Cariogenicity of uncooked and cooked traditional African foodstuffs in rats. (1987) (8)
An expanded model of bilirubin kinetics: Effect of feeding, fasting, and phenobarbital in Gilbert's syndrome (1976) (7)
THE RELATION OF ERYTHROPOIESIS TO BILE PIGMENT FORMATION* (1964) (7)
Prospect of gastroenterology and hepatology in the next century. (1999) (7)
INTESTINAL ABSORPTION OF BILE PIGMENTS. 3. THE ENTEROHEPATIC CIRCULATION OF UROBILINOGEN IN THE RAT. (1965) (7)
Effect of enamel solubility reducing agents on erosion in the rat. (1975) (7)
Effect of α-Amylase and α-Glucosidase Inhibitors on Caries Incidence and Plaque Accumulation in Rats (Short Communication) (1983) (7)
Amine fluoride and monofluorophosphate: I. Historical review of fluoride dentifrices. (1984) (7)
Cariogenicity of traditional African foodstuffs (maize, beans, sorghum, brown bread) on rat caries. (1988) (7)
The effects of diphosphonate, pyrophosphate and sodium foride on drinking habits of Osborne-Mendel rats. (1970) (7)
Issues in Liver Transplantation (1984) (7)
Cariostatic effects of monofluorophosphate in solutions and dentifrices in rats. (1989) (6)
Current concepts in diagnosis. Approach to the patient with cholestatic jaundice. (1983) (6)
Jaundice and bilirubin metabolism. (1959) (6)
Effects of aluminum and fluoride on caries, fluorine content and dissolution of rat molars. (1969) (5)
Acquired immunodeficiency syndrome and biliary tract disease. (1987) (5)
Further studies of microsomal haem oxygenase: mechanism for stimulation of enzyme activity and cellular localization. (1971) (5)
Bilirubin metabolism in the foetus. (1959) (5)
Effects of pyrophosphate/copolymer/NaF on dental calculus and caries formation in vivo. (1987) (5)
Effects of progesterone and follicular fluid during oocyte maturation on embryo development following intracytoplasmic sperm injection (ICSI) in horses (1998) (5)
Tolerance to hepatitis B antigen: a hypothesis for its termination with 'immune-RNA'. (1974) (5)
Bilirubin update: formation, transport, and metabolism. (1982) (5)
Amine fluoride and monofluorophosphate: II. Pooled results of 56 independent rat caries tests. (1984) (5)
Cariogenicity of foods. (1980) (4)
Hepatic heme metabolism: new aspects and speculations. (1983) (4)
The influence of different carbohydrates, of drinking, and of toothbrushing on oral sugar clearance in Osborne-Mendel rats. (1966) (4)
Effect of alpha-amylase and alpha-glucosidase inhibitors on caries incidence and plaque accumulation in rats. (1983) (3)
HEPATOTOXIC DRUGS CAUSING PORPHYRIA IN MAN AND ANIMALS * (1963) (3)
THE ENZYMATIC DEGRADATION OF HEMOGLOBIN TO BILE (1971) (3)
The role of protein interaction in the tissue uptake of bilirubin boy encephalopathy (1966) (3)
The effects of topical applications of sugar substitutes on the incidence of caries and bacterial agglomerate formation in rats. (1980) (3)
STUDIES OF CONGENITAL NON‐HEMOLYTIC JAUNDICE WITH C14‐BILIRUBIN * (1963) (3)
An unusual case of acute porphyria with volvulus and gangrene of the cecum. (1957) (3)
The pathogenesis of bilirubin encephalopathy: experimental models in newborn and adult animals. (1965) (3)
[Clinical and experimental porphyria]. (1952) (2)
Hemoglobin and Erythrocyte Catabolism in Rat Liver : 812 Blood (2005) (2)
Glucuronic Acid and Hyperbilirubinemia. (1958) (2)
Determination of iron in the skin. (1937) (2)
Amine fluoride and monofluorophosphate: III. Rat caries inhibition by topical applications daily or every 5th day. (1984) (2)
Prevention of hyperbilirubinemia and kernicterus by exposure to light: studies in newborn guinea pigs and premature infants. (1968) (2)
Urea content and pH of pilocarpine stimulated rat saliva. (1971) (2)
Topical effects of a quaternary ammonium compound on caries incidence and bacterial agglomerate formation in the rat. (1981) (2)
Effects of Topical Hydrogen Peroxide on Caries Incidence and Bacterial Agglomerate Formation in Rats (1980) (2)
Mechanism of Bilirubin Diglucuronide (1980) (2)
A comparison of standard bovine and equine cryodiluents for cryopreserving epididymal sperm from greater kudu ( Tragelaphus strepsiceros ) (1997) (2)
Who was disse? (1991) (2)
Measurement of mono conjugated di conjugated and unconjugated bilirubin ix alpha in normal and hyper bilirubinemic serum (1979) (1)
Internal medicine-epitomes of progress: immunodiagnosis of viral hepatitis. (1980) (1)
[Cytochrome P-450 and drug decomposing enzymes in the rat small intestinal mucosa: localization and control factors]. (1976) (1)
Stem cells: A dramatic new therapeutic tool * (2002) (1)
Viral hepatitis: dogmatism revisited. (1986) (1)
Physiology and disorders of hemoglobin degradation (1972) (1)
Harvey Sharman Marver 1934-1971. (1971) (1)
Acquired porphyria. (1963) (1)
Experimental porphyria with special reference to its implications for the human disease. (1952) (1)
Is bilirubin diglucuronide formed in vivo by transglucuronidation of bilirubin monoglucuronide (1978) (1)
Specific immunotherapy proposed for hepatitis B virus infection. (1975) (0)
[New view points in the field of biliary pigment metabolism]. (1957) (0)
Cariology, Zurich 1953-1983. Some aspects of one man's stand. (1983) (0)
Studies of Some Liver Heme Proteins and Porphyrins in Experimental Sedormid Porphyria (2008) (0)
Hepatitis and blood transfusion : proceedings (1972) (0)
1029 – APOCYTOCHROME P-450: REGULATOR OF CYTOCHROME P-450 SYNTHESIS? (1977) (0)
THE FORMATION OF BILIRUBIN FROMHEMOGLOBIN IN VIVO (0)
LEUKOCYTES AND LEUKOCYTIC DISEASE (2005) (0)
STEVEN SCHENKER , NANCYH . DAWBER , AND (2013) (0)
Hepatic GSH in hexa-chlorobenzene-induced porphyria. (1962) (0)
Metabolism and Excretion of Bile Pigments1 (1979) (0)
Extensive research is being conducted, both here and abroad, on this relatively rare and perplexing disease (1952) (0)
ophthalmic oil emulsions containing water prostaglandins (2008) (0)
UDP-glucuronic acid-dependent formation of bilirubin diglucuronide from bilirubin monoglucuronide by rat liver microsomes (1978) (0)
[Recent results in the field of porphyria]. (1953) (0)
Extrahepatic manifestations in liver diseases : proceedings of the 69th Falk Symposium held in Basel, Switzerland, October 15-17, 1992 (1993) (0)
Genetic disorders of bilirubin metabolism (1998) (0)
Transmission of hepatitis B by a finger-stick device. (1992) (0)
Acute and chronic liver diseases : molecular biology and clinics : proceedings of the 87th Falk Symposium (X International Congress of Liver Diseases, Part II of the Basel Liver Week 1995), held in Basel, Switzerland, october 19-21, 1995 (1996) (0)
Gastroenterology in the next century: Megatrends in science and practice (1998) (0)
THE ENZYMlIA TIC CONVERSION OF HEME TO BILIRUBIN BY 1 HICROSOMAL HEME OXYGENASE (0)
[A caries-preventing sodium fluoride-tin fluoride toothpaste]. (1972) (0)
Clinical Manifestations of Glycogen Storage Diseases (2008) (0)
Bilirubin Metabolism: An Overview (1975) (0)
EXOGENOUS HEME FUNCTIONALLY RECONSTITUTES HEPATIC CYTOCHROME P-450 IN VIVO (1980) (0)

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