Rudolph Leibel | Academic Influence

Rudolph Leibel's AcademicInfluence.com Rankings

Rudolph Leibel

Law

#1571

World Rank

#1971

Historical Rank

#776

USA Rank

Common Law

#59

World Rank

#66

Historical Rank

#13

USA Rank

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Law

Rudolph Leibel's Degrees

Doctorate Medicine University of Pennsylvania

Why Is Rudolph Leibel Influential?

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According to Wikipedia, Rudolph Leibel is the Christopher J. Murphy Professor of Diabetes Research, Professor of Pediatrics and Medicine at Columbia University Medical Center, and Director of the Division of Molecular Genetics in the Department of Pediatrics. He is also co-director of the Naomi Berrie Diabetes Center and executive director of the Russell and Angelica Berrie Program in Cellular Therapy, Co-director of the New York Obesity Research Center and the Columbia University Diabetes and Endocrinology Research Center.

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Rudolph Leibel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Obesity is associated with macrophage accumulation in adipose tissue. (2003) (9084)
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons (2008) (1973)
Changes in energy expenditure resulting from altered body weight. (1995) (1859)
The Long-Term Stability of the Human Gut Microbiota (2013) (1559)
CCR2 modulates inflammatory and metabolic effects of high-fat feeding. (2006) (1531)
Phenotypes of Mouse diabetes and Rat fatty Due to Mutations in the OB (Leptin) Receptor (1996) (1183)
Effects of gender, body composition, and menopause on plasma concentrations of leptin. (1996) (849)
Obesity and leptin resistance: distinguishing cause from effect (2010) (722)
Waist circumference and cardiometabolic risk: a consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes Association. (2007) (622)
Generation of pluripotent stem cells from patients with type 1 diabetes (2009) (566)
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. (2005) (520)
Medical progress: Obesity. (1997) (492)
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. (2008) (436)
Obesity Pathogenesis: An Endocrine Society Scientific Statement. (2017) (382)
Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli. (2008) (380)
Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight. (2008) (376)
Is the energy homeostasis system inherently biased toward weight gain? (2003) (376)
Waist Circumference and Cardiometabolic Risk: A Consensus Statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes Association (2007) (369)
Responses of Gut Microbiota to Diet Composition and Weight Loss in Lean and Obese Mice (2012) (367)
Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. (2002) (365)
The gut microbiota in human energy homeostasis and obesity (2015) (346)
Regulation of Fto/Ftm gene expression in mice and humans. (2008) (315)
The Molecular Genetics of Rodent Single Gene Obesities* (1997) (311)
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. (1998) (306)
Phenotype of fatty Due to Gln269Pro Mutation in the Leptin Receptor (Lepr) (1996) (306)
Effects of weight change on plasma leptin concentrations and energy expenditure. (1997) (299)
Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse (1996) (290)
Diminished energy requirements in reduced-obese patients. (1984) (268)
Adaptive thermogenesis in humans (2010) (267)
Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function. (2000) (266)
MC4R-dependent suppression of appetite by bone-derived lipocalin 2 (2017) (258)
The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7. (1995) (255)
Dietary fat is not a major determinant of body fat. (2002) (253)
The physiology of body weight regulation: relevance to the etiology of obesity in children. (1998) (245)
Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men. (2016) (244)
Phenotype of the Obese Koletsky (f) Rat Due to Tyr763Stop Mutation in the Extracellular Domain of the Leptin Receptor (Lepr): Evidence for Deficient Plasma-to-CSF Transport of Leptin in Both the Zucker and Koletsky Obese Rat (1997) (234)
Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. (2003) (230)
Leptin Regulation of Agrp and Npy mRNA in the Rat Hypothalamus (2001) (220)
Waist circumference and cardiometabolic risk : a consensus statement from Shaping America ’ s Health : Association for Weight Management and Obesity Prevention (2007) (217)
Brief fasting, stress, and cognition in children. (1981) (214)
Autonomic nervous system activity in weight gain and weight loss. (1995) (210)
To eat or not to eat - how the gut talks to the brain. (2003) (209)
Iron deficiency and behavior. (1976) (207)
Waist Circumference and Cardiometabolic Risk (2007) (205)
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells (2020) (196)
The role of leptin in the control of body weight. (2002) (192)
20 years of leptin: role of leptin in energy homeostasis in humans. (2014) (192)
Challenges and opportunities of defining clinical leptin resistance. (2012) (187)
Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells (2014) (185)
Effect of puberty on the relationship between circulating leptin and body composition. (2000) (180)
Molecular mapping of the mouse ob mutation. (1991) (176)
Human oocytes reprogram somatic cells to a pluripotent state (2011) (166)
Physiologic basis for the control of body fat distribution in humans. (1989) (164)
Heart rate variability as a measure of autonomic function during weight change in humans. (1991) (162)
Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts. (1997) (159)
Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene. (2001) (157)
Metabolically healthy and unhealthy obese – the 2013 Stock Conference report (2014) (154)
Epigenetic regulation of serotonin transporter expression and behavior in infant rhesus macaques (2010) (150)
Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects. (2010) (149)
Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). (1991) (148)
The role of leptin in human physiology. (1999) (147)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels (2016) (147)
An exploratory investigation of the morphology and biochemistry of cellulite. (1998) (146)
Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice. (2014) (145)
Molecular physiology of weight regulation in mice and humans (2008) (142)
β-Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome (2014) (141)
Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model. (2006) (140)
Determinants of leptin gene expression in fat depots of lean mice. (2002) (137)
Role of Gonadal Steroids in the Sexual Dimorphisms in Body Composition and Circulating Concentrations of Leptin1 (1999) (137)
A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children. (2011) (136)
Iron deficiency and behavioral development in infants and preschool children. (1986) (135)
Energy intake in weight-reduced humans (2010) (132)
The fat cell. (1989) (132)
Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. (1996) (132)
Hyperleptinemia: an early sign of juvenile obesity. Relations to body fat depots and insulin concentrations. (1996) (131)
Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling* (2010) (131)
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference (2002) (125)
Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet–Biedl syndrome (2010) (124)
Understanding obesity in youth. A statement for healthcare professionals from the Committee on Atherosclerosis and Hypertension in the Young of the Council on Cardiovascular Disease in the Young and the Nutrition Committee, American Heart Association. Writing Group. (1996) (123)
11C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls (2009) (123)
Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Québec Family Study (1999) (118)
Effects of systemic growth hormone (GH) administration on regional adipose tissue distribution and metabolism in GH-deficient children. (1989) (117)
Body fat redistribution after weight gain in women with anorexia nervosa. (2005) (117)
Tackling a weighty problem (1992) (117)
Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice. (2004) (114)
Leptin: A Molecule Integrating Somatic Energy Stores, Energy Expenditure and Fertility (1998) (109)
Site- and sex-related differences in adrenoreceptor status of human adipose tissue. (1987) (106)
Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation. (1997) (106)
In vitro lipid synthesis in human adipose tissue from three abdominal sites. (1993) (105)
Exonic and Intronic Sequence Variation in the Human Leptin Receptor Gene (LEPR) (1997) (103)
Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys. (2007) (103)
Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome (2016) (102)
Differentiation of hypothalamic-like neurons from human pluripotent stem cells. (2015) (100)
Leptin reverses declines in satiation in weight-reduced obese humans. (2012) (99)
Molecular mapping of the mouse db mutation. (1990) (98)
The leptin receptor mediates apparent autocrine regulation of leptin gene expression. (1997) (97)
Mechanism of free fatty acid re-esterification in human adipocytes in vitro. (1990) (96)
Regulation of Hypothalamic Proopiomelanocortin by Leptin in Lean and Obese Rats (1999) (95)
Glutaric acidemia (1980) (95)
Heterozygosity for Lepob or Leprdb affects body composition and leptin homeostasis in adult mice. (1998) (94)
Food deprivation and hypothalamic neuropeptide gene expression: effects of strain background and the diabetes mutation. (1991) (92)
FOXO1 Inhibition Yields Functional Insulin-Producing Cells In Human Gut Organoid Cultures (2014) (92)
Concentrations of adipsin in blood and rates of adipsin secretion by adipose tissue in humans with normal, elevated and diminished adipose tissue mass. (1994) (92)
DNA methylation as a risk factor in the effects of early life stress (2011) (92)
Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity. (1997) (91)
iPSC-derived β cells model diabetes due to glucokinase deficiency. (2013) (89)
Plasma leptin in diabetic and insulin-treated diabetic and normal rats. (1998) (88)
Autosomal dominant growth hormone (GH) deficiency type II: the Del32-71-GH deletion mutant suppresses secretion of wild-type GH. (2000) (87)
Molecular pathophysiology of metabolic effects of antipsychotic medications (2014) (84)
Sexual dimorphism in circulating leptin concentrations is not accounted for by differences in adipose tissue distribution (2001) (83)
Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2 (2009) (82)
Diabetes and oral disease: implications for health professionals (2012) (81)
Genetic Association Analysis of 30 Genes Related to Obesity in a European American Population (2013) (79)
A missing link in body weight homeostasis: the catabolic signal of the overfed state. (2014) (79)
A comparative study of different means of assessing long-term energy expenditure in humans. (1996) (78)
Hypomorphism of Fto and Rpgrip1l causes obesity in mice. (2016) (77)
Aluminum Toxicity in Infants and Children (1986) (76)
Clinical review 107: Role of gonadal steroids in the sexual dimorphisms in body composition and circulating concentrations of leptin. (1999) (76)
Energy intake required to maintain body weight is not affected by wide variation in diet composition. (1992) (75)
Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adults (2006) (73)
Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. (2001) (73)
Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia (2014) (73)
Reprogramming within hours following nuclear transfer into mouse but not human zygotes. (2011) (72)
Lipolysis in Intraabdorninal Adipose Tissues of Obese Women and Men (1993) (70)
Genomic Organization of the Human GHRELIN Gene (2000) (70)
The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein. (2002) (69)
Suggestive linkages between markers on human 1p32-p22 and body fat and insulin levels in the Quebec Family Study. (1997) (69)
Models of energy homeostasis in response to maintenance of reduced body weight (2016) (68)
Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans. (1989) (67)
Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans (2013) (66)
The subgingival microbiome, systemic inflammation and insulin resistance: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (2017) (65)
Considerations Regarding the Genetics of Obesity (2008) (65)
Effects of obesity and stable weight reduction on UCP2 and UCP3 gene expression in humans. (1999) (65)
GLUCOSE AND LIPID HOMEOSTASIS AND INFLAMMATION IN HUMANS FOLLOWING AN ISOCALORIC KETOGENIC DIET (2019) (64)
Food deprivation and age modulate neuropeptide gene expression in the murine hypothalamus and adrenal gland. (1991) (63)
Positional Cloning of “Lisch-like”, a Candidate Modifier of Susceptibility to Type 2 Diabetes in Mice (2008) (63)
Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. (2012) (63)
Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult mice. (1998) (62)
Reproducibility and accuracy of body composition assessments in mice by dual energy x-ray absorptiometry and time domain nuclear magnetic resonance. (2009) (62)
Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human. (1996) (60)
Iron deficiency, brain biochemistry, and behavior (1982) (60)
Estimating energy expenditure in mice using an energy balance technique (2013) (60)
Genetic modifiers of Leprfa associated with variability in insulin production and susceptibility to NIDDM. (1997) (60)
Lack of beta 3-adrenergic effect on lipolysis in human subcutaneous adipose tissue. (1993) (58)
Absence of Linkage of Obesity and Energy Metabolism to Markers Flanking Homologues of Rodent Obesity Genes in Pima Indians (1996) (58)
β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells (2017) (56)
The Gln223 Arg and Lys656 Asn Polymorphisms in the Human Leptin Receptor Do Not Associate With Traits Related to Obesity (1997) (56)
Lipolysis in intraabdominal adipose tissues of obese women and men. (1993) (56)
Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in rats. (2001) (55)
Pathophysiology of childhood obesity. (1988) (54)
Roles of the placenta in fetal brain development (2011) (53)
Cardiac autonomic nervous system activity in obese and never-obese young men. (1997) (53)
Iron deficiency and cognitive test performance in preschool children (1983) (53)
Effects of chronic weight perturbation on energy homeostasis and brain structure in mice. (2011) (53)
Molecular Genetic Analysis of a Human Neuropeptide Y Receptor (1997) (52)
Fat cell size and adipokine expression in relation to gender, depot and metabolic risk factors in morbidly obese adolescents (2013) (52)
Fluoride Supplementation for Children: Interim Policy Recommendations (1995) (51)
Genetic and physiologic analysis of the role of uncoupling protein 3 in human energy homeostasis. (1999) (51)
TNF-α up-regulates protein level and cell surface expression of the leptin receptor by stimulating its export via a PKC-dependent mechanism. (2012) (50)
Mutation screening and association studies of the human uncoupling protein 3 gene in normoglycemic and diabetic morbidly obese patients. (1999) (50)
Assessment of uncoupling activity of the human uncoupling protein 3 short form and three mutants of the uncoupling protein gene using a yeast heterologous expression system (1999) (47)
Molecular physiology of syndromic obesities in humans (2005) (46)
Medical care for obese patients: advice for health care professionals. (2002) (46)
The Carbohydrate-Insulin Model of Obesity Is Difficult to Reconcile With Current Evidence. (2018) (46)
Whole‐Exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity (2014) (45)
FTO genotype impacts food intake and corticolimbic activation. (2018) (45)
Retinoic acid receptor signaling is required to maintain glucose‐stimulated insulin secretion and β‐cell mass (2015) (44)
In silico mutagenesis: a case study of the melanocortin 4 receptor (2009) (44)
Effects of exogenous gonadal steroids on leptin homeostasis in rats. (1999) (44)
Effects of leptin deficiency and short-term repletion on hepatic gene expression in genetically obese mice. (2001) (43)
VMAT2 quantitation by PET as a biomarker for β‐cell mass in health and disease (2008) (43)
Diet composition and energy balance in humans. (1998) (43)
Effects of ambient temperature on adaptive thermogenesis during maintenance of reduced body weight in mice. (2012) (42)
Weight Loss after Bariatric Surgery in Morbidly Obese Adolescents with MC4R mutations (2013) (42)
Quantitative Trait Locus Mapping of Genetic Modifiers of Metabolic Syndrome and Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice: Identification of a Locus for Metabolic Syndrome and Increased Atherosclerosis on Chromosome 4 (2004) (42)
Alterations in adipocyte free fatty acid re-esterification associated with obesity and weight reduction in man. (1985) (42)
Effects of weight loss and leptin on skeletal muscle in human subjects. (2011) (42)
Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine. (2008) (41)
Genomic structure of the human OB receptor and identification of two novel intronic microsatellites. (1996) (39)
Molecular genetic linkage maps of mouse chromosomes 4 and 6. (1991) (39)
Impracticality of egg donor recruitment in the absence of compensation. (2011) (38)
Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin (2013) (38)
Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium (2015) (38)
Effects of leptin receptor mutation on Agrp gene expression in fed and fasted lean and obese (LA/N-faf) rats. (2000) (38)
Respective Contributions of Maternal Insulin Resistance and Diet to Metabolic and Hypothalamic Phenotypes of Progeny (2011) (37)
Proteasome inhibitors, including curcumin, improve pancreatic β-cell function and insulin sensitivity in diabetic mice (2016) (37)
Effects of nutrient cues on formula intake in 5-week-old infants (1979) (36)
Effects of chronic leptin infusion on subsequent body weight and composition in mice: Can body weight set point be reset?aa (2014) (35)
Is obesity due to a heritable difference in 'set point' for adiposity? (1990) (35)
The FTO Gene and Measured Food Intake in 5‐ to 10‐Year‐Old Children Without Obesity (2019) (35)
Functional Consequences of the Human Leptin Receptor (LEPR) Q223R Transversion (2009) (35)
Methodologic considerations for measuring energy expenditure differences between diets varying in carbohydrate using the doubly labeled water method. (2019) (34)
A radioisotopic technique for analysis of free fatty acid reesterification in human adipose tissue. (1985) (34)
Obesity genes: Molecular and metabolic mechanisms (1997) (33)
Excess energy intake and low energy expenditure as predictors of obesity (1998) (32)
Mahoganoid and Mahogany Mutations Rectify the Obesity of the Yellow Mouse by Effects on Endosomal Traffic of MC4R Protein* (2011) (31)
Metabolic and hemodynamic responses to endogenous and exogenous catecholamines in formerly obese subjects. (1991) (31)
Metabolic and hemodynamic responses to exercise in subcutaneous adipose tissue and skeletal muscle. (2002) (31)
Adrenergic control of adipocyte lipolysis in trauma and sepsis. (1987) (30)
Regional differences in adrenoreceptor status of adipose tissue in adults and prepubertal children. (1991) (30)
Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease (2014) (30)
Regional changes in adrenergic receptor status during hypocaloric intake do not predict changes in adipocyte size or body shape. (1990) (30)
Mechanisms for LEPR-mediated regulation of leptin expression in brown and white adipocytes in rat pups. (2001) (30)
Molecular mapping of obesity genes (2004) (30)
Association Between Nitrate‐Reducing Oral Bacteria and Cardiometabolic Outcomes: Results From ORIGINS (2019) (29)
Describing the Weight‐Reduced State: Physiology, Behavior, and Interventions (2021) (28)
Cross-sectional and Test-Retest Characterization of PET with [18F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes (2015) (28)
ILDR2: An Endoplasmic Reticulum Resident Molecule Mediating Hepatic Lipid Homeostasis (2013) (28)
Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss. (2011) (28)
Energy in, energy out, and the effects of obesity-related genes. (2008) (27)
Obesity in childhood. (1989) (27)
The threshold shift paradigm of obesity: evidence from surgically induced weight loss. (2014) (27)
Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS. (2016) (26)
Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production (2020) (26)
Proopiomelanocortin, agouti-related protein, and leptin in human cerebrospinal fluid: correlations with body weight and adiposity. (2015) (26)
A differential dielectric affinity glucose sensor. (2014) (25)
And finally, genes for human obesity (1997) (25)
Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development. (2019) (25)
Studies regarding the impact of micronutrient status on behavior in man: iron deficiency as a model. (1982) (25)
Genetic variability in responses to caloric restriction in animals and in regulation of metabolism and obesity in humans. (2001) (25)
Radioisotopic method for the measurement of lipolysis in small samples of human adipose tissue. (1984) (24)
Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats. (1996) (24)
Loss of the imprinted, non-coding Snord116 gene cluster in the interval deleted in the Prader Willi syndrome results in murine neuronal and endocrine pancreatic developmental phenotypes (2017) (24)
Effects of systemic growth hormone (GH) administration on regional adipose tissue in children with non-GH-deficient short stature. (1992) (24)
Iron Deficiency: Behavior and Brain Biochemistry (1979) (24)
A MEMS differential viscometric sensor for affinity glucose detection in continuous glucose monitoring (2013) (24)
Molecular Genetics of Rodent and Human Single Gene Mutations Aﬀecting Body Composition (2003) (24)
Lipolytic effects on diacylglycerol accumulation in human adipose tissue in vitro. (1990) (23)
Whole body [11C]-dihydrotetrabenazine imaging of baboons: biodistribution and human radiation dosimetry estimates (2008) (23)
Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study) (2011) (23)
Alcohol and calories: a matter of balance. (1993) (23)
BIOCHEMICAL AND BEHAVIOURAL ASPECTS OF SIDEROPENIA (1979) (23)
The effect of the metabolite glycerol on food intake and body weight in rats (1980) (22)
Haplotype analysis of the growth hormone releasing hormone receptor locus in three apparently unrelated kindreds from the indian subcontinent with the identical mutation in the GHRH receptor (2003) (22)
Triiodothyronine and leptin repletion in humans similarly reverse weight-loss-induced changes in skeletal muscle. (2018) (22)
Genetic Defects in the Control of Growth Hormone Secretion (1998) (22)
Determination of the half life of circulating leptin in the mouse (2016) (22)
A role for foregut tyrosine metabolism in glucose tolerance (2019) (22)
Waist circumference and cardiometabolic risk: a consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes (2007) (22)
Genetic variation and nutrition in obesity: approaches to the molecular genetics of obesity. (1990) (20)
Measurement of glycerol turnover by infusion of nonisotopic glycerol in normal and injured subjects. (1984) (19)
Analysis of 30 Genes (355 SNPS) Related to Energy Homeostasis for Association with Adiposity in European-American and Yup’ik Eskimo Populations (2008) (19)
Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) and electrophoretic assays for the mouse obese (Lepob) mutation. (1997) (19)
Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells (2016) (19)
Single gene obesities in rodents: possible relevance to human obesity. (1997) (19)
A biologic radar system for the assessment of body mass the model of a geometry sensitive endocrine system is presented. (1977) (18)
Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus. (1995) (18)
Pathophysiology of drug induced weight and metabolic effects: findings from an RCT in healthy volunteers treated with olanzapine, iloperidone, or placebo (2018) (18)
FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications1[S] (2018) (18)
PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons (2017) (17)
The genetics of obesity. (1998) (17)
Effects of rapid glucose infusion on in vivo and in vitro free fatty acid re-esterification by adipose tissue of fasted obese subjects. (1989) (17)
A molecular genetic method for genotyping fatty (fa/fa) rats. (1993) (17)
Strategies for the molecular genetic analysis of obesity in humans. (1993) (17)
New light on obesity. (1988) (16)
Energy homeostasis in leptin deficient Lepob/ob mice (2017) (16)
Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci. (2021) (16)
Effects of leptin and cholecystokinin in rats with a null mutation of the leptin receptor Lepr(fak). (2000) (16)
The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity. (2006) (16)
Behavioral and biochemical correlates of iron deficiency. (1977) (16)
Calorie restriction and iopanoic acid effects on thyroid hormone metabolism. (1990) (16)
Molecular mapping of the tubby (tub) mutation on mouse chromosome 7. (1996) (15)
Metabolic Responses to Weight Perturbation (2010) (15)
Genetic Analysis of Complex Disorders (1991) (15)
Human growth hormone-releasing hormone receptor (GHRHR) maps to a YAC at Chromosome 7p15 (1994) (15)
Effects of a novel MC4R agonist on maintenance of reduced body weight in diet induced obese mice (2014) (14)
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity (2020) (14)
Lessons from Rodent Models of Obesity (2015) (14)
Significance of Bayley Scale score changes following iron therapy. (1978) (14)
Obesity: a game of inches. (1995) (14)
The rat corpulent (cp) mutation maps to the same interval on (Pgm1-Glut1) rat chromosome 5 as the fatty (fa) mutation. (1997) (14)
Bardet-Biedl Syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons. (2021) (14)
Identifying functional relationships among human genes by systematic analysis of biological literature (2002) (13)
Genetic map of rat Chromosome 5 including the fatty (fa) locus (2004) (13)
Application of Receiver-Operator Analysis to Diagnostic Tests of Iron Deficiency in Man (1984) (13)
Nutritionally-induced changes in parasympathetic function (1991) (13)
Resistance Training Reduces Skeletal Muscle Work Efficiency in Weight-reduced and Non-weight-reduced Subjects (2018) (12)
Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain (2017) (12)
DMSO increases efficiency of genome editing at two non-coding loci (2018) (12)
Location, location, location... (2008) (12)
The links between obesity, leptin, and prostate cancer. (2006) (12)
Clinical review 28: A biological basis for human obesity. (1991) (12)
Physiological consequences of transient hyperleptinemia during discrete developmental periods on body weight in mice (2020) (12)
Municipal child health services: a ten-year reorganization. (1976) (12)
Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells (2018) (12)
Neurofunctional imaging of β‐cell dynamics (2012) (11)
The role of Rpgrip1l, a component of the primary cilium, in adipocyte development and function (2018) (11)
Metabolic characterization of obesity. (1985) (11)
Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight (2020) (11)
Considerations Regarding the Genetics (2008) (11)
Yellow mice, red hair, and childhood obesity: the melanocortinergic pathway in energy homeostasis. (2001) (11)
A MEMS differential affinity sensor for continuous glucose detection (2011) (11)
A More Sensitive and Selective Ultraviolet Absorption Criterion for Mineral Oil (1962) (11)
Effects of early pregnancy on regional adipose tissue metabolism. (1991) (11)
Subgingival Microbiota and Longitudinal Glucose Change: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS) (2019) (11)
ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression. (2016) (11)
11 C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls (2009) (10)
Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome. (1992) (10)
Body weight regulation: neural, endocrine, and autocrine mechanisms. (2002) (10)
Microdissection of proximal mouse Chromosome 6: identification of RFLPs tightly linked to the ob mutation (1993) (10)
Genetic analysis of complex disorders. Molecular mapping of obesity genes in mice and humans. (1991) (10)
Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits (2020) (10)
Estimating energy expenditure in mice using an energy balance technique (2013) (10)
Effect of glycerol on weight loss and hunger in obese patients. (1980) (9)
An Apparent Role for Alox15 in the Pathogenesis of Diabetes in the NOD Mouse (2008) (9)
The postnatal leptin surge in mice is variable in both time and intensity and reflects nutritional status (2021) (9)
Brain reorganization following weight loss. (2012) (9)
FTO gains function (2010) (9)
FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice (2021) (9)
Fat as fuel and metabolic signal. (2009) (8)
The molecular genetics of the melanocortin pathway and energy homeostasis. (2006) (8)
Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease (2020) (8)
The Zucker fatty (fa) gene is not a mutation of corticotropin-releasing factor. (1993) (7)
The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse Chromosome 6 (2004) (7)
Differences in brain structure and function in children with the FTO obesity‐risk allele (2020) (7)
Auto-Regulation of Leptin Neurobiology. (2019) (7)
A MEMS differential dielectric sensor for continuous glucose monitoring (2012) (6)
iPSC-derived β cells model diabetes due to glucokinase deficiency. (2017) (6)
Thanatology and Medical Economics (1977) (6)
Acute inhibition of somatotroph response to human growth hormone-releasing hormone 1-44 occurs following three hours but not one hour of growth hormone infusion. (1989) (6)
Frequency and characterization of mutations in genes in a large cohort of patients referred to MODY registry (2021) (5)
What constitutes a sufficient psychobiologic explanation for obesity? (1984) (5)
Continuous Monitoring of Glucose in Subcutaneous Tissue Using Microfabricated Differential Affinity Sensors (2012) (5)
Human stem cell model of HNF1A deficiency shows uncoupled insulin to C-peptide secretion with accumulation of abnormal insulin granules (2021) (5)
Rapid Publication Phenotype offatty Due to Gln269Pro Mutation in the Leptin Receptor (Lepr) (1996) (5)
The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis (1999) (5)
Reply to R Weinsier et al (2001) (5)
ILDR2 has a negligible role in hepatic steatosis (2018) (5)
Reply to DS Ludwig and CB Ebbeling. (2016) (4)
Utility of a C-jun microsatellite marker in determining gene dosage for fatty (fa). (1993) (4)
Corrigendum: MC4R-dependent suppression of appetite by bone-derived lipocalin 2 (2017) (4)
Adaptive Responses to Weight Loss (2014) (4)
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency (2022) (4)
A clinical perspective on peptides and food intake. (1992) (3)
Mutation in the leptin receptor (Leprfa) causes fat-storage-independent hyperleptinaemia in neonatal rats (1999) (3)
The First Documentation of Reproduction in a Genetically Obese Female fa/cp Rat (1994) (3)
Partial duplication in the Leprdb-Pas mutation is a result of unequal crossing over (1998) (3)
Significance of Bayley Scale score changes following iron therapy. II (1979) (3)
Mutational Analysis of the Wolfram Syndrome Gene (WFS1) in Greek and Dominican Patients (2002) (3)
SNORD116 and growth hormone therapy impact IGFBP7 in Prader–Willi syndrome (2021) (3)
Methodologic Issues in Doubly Labeled Water Measurements of Energy Expenditure During Very Low-Carbohydrate Diets (2018) (3)
Physiological responses to leptin levels in lipodystrophy: a model for other hypoleptinemias? (2018) (3)
Energy expenditure and body-weight gain. (1988) (3)
Gene expression atlas of energy balance brain regions (2021) (3)
Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes (2021) (3)
Functional genomic characterization of the FTO locus in African Americans (2019) (2)
Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice (2022) (2)
Misleading or factually incorrect statements in the American Journal of Clinical Nutrition Perspectives article by Ludwig et al. (2022) (2)
Overview of Human Monogenic, Nonsyndromic and Syndromic Obesity (2007) (2)
A Novel Mutation of Glutamate Dehydrogenase (H262Y) in an Infant with Hyperinsulinemic Hypoglycemia and Hyperammonemia (2000) (2)
Obesity: Common Symptom of Diverse Gene-Based Metabolic Dysregulations Single Gene Obesities in Rodents: Possible Relevance to Human Obesity 1,2 (1997) (2)
Delay-induced uncertainty in the glucose-insulin system: Pathogenicity for obesity and type-2 diabetes mellitus (2022) (2)
Amendment history : Retraction ( March 2017 ) iPSC-derived b cells model diabetes due to glucokinase deficiency (2018) (2)
Potential Bias of Doubly Labeled Water for Measuring Energy Expenditure Differences Between Diets Varying in Carbohydrate (2018) (2)
A radioisotopic method for the measurement of free fatty acid turnover and adrenoceptor response in small fragments of human adipose tissue. (1985) (1)
Locus D1S21 contains exonic sequence from the C8 beta component of complement. (1994) (1)
Molecular Physiology of Monogenic and Syndromic Obesities in Humans (2007) (1)
Role of adipocyte geometry in eating behavior. (1978) (1)
Contents Vol. 70, 1999 (1999) (1)
[Physical activity exhibits differences in the action of fat metabolism in men and women--results of a microdialysis study]. (1999) (1)
Fat - feast or famine? (2003) (1)
The roles of nature and nurture in childhood obesity. (1989) (1)
Obesity Genes and Insulin Resistance Syndrome (1997) (1)
on the physical , cytogenetic , and genetic maps of chromosome 7 . The human obese ( OB ) gene : RNA expression pattern and mapping (2007) (1)
Does diet composition have structural consequences in the hypothalamus? (2013) (1)
Locus D1S21 contains exonic sequence from the C8β component of complement (1994) (1)
Protein phosphorylation in isolated human adipocytes-adrenergic control of the phosphorylation of hormone-sensitive lipase. (1990) (1)
1) Is the Antidepressant Effect of Hypericum Extracts Depending on Their Hyperforin Content? 2) And Again. Is Homeopathy a Placebo Response? 3) A Homeopathic Nosode for Influenza-Like Syndromes (1999) (1)
The effect of Escherichia coli endotoxin on the adrenergic control of lipolysis in the human adipocyte. (1989) (1)
Argl83His, a New Mutational "Hot-Spot" in the Growth Hormone Gene (2000) (1)
Word selection and weight bias (2021) (1)
Elucidating the Role of ILDR2 in the Unfolded Protein Response and its Effect on Nonalcoholic Steatohepatitis (2017) (0)
Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men12 (2016) (0)
Abstract P052: Subgingival Dysbiosis Predicts Longitudinal Glucose Change (2017) (0)
Functional Genomic Characterization of the Fat Mass and Obesity-Associated (FTO) Locus in African Americans. (2019) (0)
ratssecretion and sympathetic outflow in Acidic fibroblast growth factor activates (2013) (0)
Behavioral and biochemical correlates of iron deficiency. A review (1977) (0)
rodents and monkeys cause potent but reversible hypophagia and weight loss in Monoclonal antibody antagonists of hypothalamic FGFR 1 (2007) (0)
Faith The Long-Term Stability of the Human Gut Microbiota (2013) (0)
AproinflammatorypeptidefromHelicobacter pylori activatesmonocytestoinducelymphocytedysfunctionandapoptosis (2006) (0)
oxidationloss on exercise efficiency and substrate Separate and combined effects of exercise training and (2015) (0)
GROWTH HORMONE (GH) THERAPY: EFFECTS ON IN VITRO ADIPOCYTE INSULIN (I) SENSITIVITY ODRREIATE WITH ANTHROPOMETRIC RESPONSE (1987) (0)
Body weight regulation. “Why is it so hard to keep weight off? (2010) (0)
Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity (2019) (0)
Letter: A note of caution. (1976) (0)
Can a weight loss medication impact ability to delay reward in the obese (2014) (0)
Pluripotent Stem Cells in Endocrinology (2016) (0)
Muscle blood flow and lactate and glycerol responses to exercise are gender-dependent (1997) (0)
expression in brown and white adipocytes in rat pups Mechanisms for LEPR-mediated regulation of leptin (2015) (0)
Use of Clinical Data in Genetic Research: The Value of Narrative Data in Electronic Medical Records (1999) (0)
Leibel in Children The Physiology of Body Weight Regulation : Relevance to the Etiology of Obesity Services (0)
Commentary on “Long-Term Calorie Restriction Reduces Energy Expenditure in Aging Monkeys” (1999) (0)
Diet composition and energy balance in humans 1–3 (1999) (0)
Localization of a (CA)n repeat in glucagon-like peptide-1 receptor gene (Glp1r) to proximal mouse Chromosome 17 and its linkage to other markers (1995) (0)
EFFECTS OF SUPERVISED NUTRITIONAL, HEALTH, AND EXERCISE EDUCATION ON RISK FACTORS FOR TYPE 2 DIABETES MELLITUS IN ADOLESCENTS. (2003) (0)
homeostasis and brain structure in mice Effects of chronic weight perturbation on energy (2011) (0)
ILDR2 Alters Hepatic Phospholipid Composition via MBOAT7—Effects on Liver Fat (2018) (0)
Author response: Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci (2020) (0)
Abstract 368: Mechanisms of Arrhythmogenic Substrates in Lipotoxic Heart (2020) (0)
Regulation of intracellular signaling and neuron function by Bardet-Biedl Syndrome proteins in patient-specific iPSC-derived neurons (2020) (0)
14th Marabou Symposium - the Nutritional Role of Fat - Discussion (1992) (0)
unloadingeffects of thyroid hormone and mechanical Novel transitions in MHC isoforms: separate and (2015) (0)
Reply to DS Ludwig et al. (2019) (0)
Retinoic acid receptor signaling is required to maintain glucoseâ•’stimulated insulin secretion and Î2â•’cell mass (2020) (0)
Heightened sensitivity to high-calorie foods in children at risk for obesity: insights from behavior, neuroimaging, and genetics. (2023) (0)
The mahoganoid mutation ( Mgrn 1 md ) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity Loan (2006) (0)
Dynamic Regulation of K and Ca Currents in Lipotoxic Supraventricular Arrhythmias (2020) (0)
Panel discussion: early nutrition in adult disease prevention. (1989) (0)
Molecular Genetic Approaches to Obesity (2020) (0)
PET quantification of {beta} cell mass in diabetes with [11C]DTBZ (2008) (0)
[11C]DTBZ PET quantification of β cell mass in long standing type I diabetes (2008) (0)
Subject Index Vol. 70, 1999 (1999) (0)
Discovery of New Drugs for Weight Loss and Prevention of Weight Regain (2016) (0)
Toward optimal health: the experts discuss advances in diabetes management in women. Interview by Jodi Godfrey. (2004) (0)
European Society for Classical Natural Medicine (ESCNM) (1999) (0)
The Expert Weighs In Birth of the New York Obesity Research Center An Interview with Founding Director Theodore B. VanItallie, M.D., and Deputy Director Rudolph L. Leibel, M.D. (2006) (0)
Ratobesity genefatty (fa) mapstochromosome 5:Evidence for homology withthemousegenediabetes (db) (1991) (0)
T148. Structural and Functional Brain Differences in Children With the FTO Obesity Risk Allele (2019) (0)
The Rare and Atypical Diabetes Network (RADIANT) Study: Design and Early Results. (2023) (0)
Glucose homeostasis in three interstrains (LA/N-BN/Crl cp/cp; Zuc13M-BN/Crl fa/fa; and Zuc13m-LA/N fa/cp) of genetically obese rats (1996) (0)
245-OR: CIS-Regulatory Architecture of Human ESC-Derived Hypothalamic Neuron Differentiation Aids in Variant-to-Gene Mapping of Type 2 Diabetes Related Traits (2020) (0)
An ounce of prevention. (1996) (0)
Jules Hirsch, M.D. (1927‐2015) (2015) (0)
Predicted loss of function alleles in Bassoon (BSN) are associated with obesity (2023) (0)
Genetics of Body Weight Regulation (2012) (0)
Technologies, strategies, and cautions when deconvoluting genome‐wide association signals: FTO in focus (2023) (0)
[Skin aging--a problem of nutritional care?]. (1999) (0)
Understanding obesity: genes and environment in the determination of body weight (2007) (0)
Challenges of Measuring Energy Expenditure Differences Between Diets Varying in Carbohydrate using Doubly Labeled Water (2018) (0)
Sounding board. Thanatology and medical economics. (1977) (0)
A Note of Caution (1976) (0)
HNF1A deficiency causes reduced calcium levels, accumulation of abnormal insulin granules and uncoupled insulin to C-peptide secretion in a stem cell model of MODY3 (2021) (0)
Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity (2019) (0)

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