Ruedi Aebersold
#26,448
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Swiss biologist
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Ruedi Aebersoldbiology Degrees
Biology
#732
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#1274
Historical Rank
Biochemistry
#99
World Rank
#128
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Biology
Ruedi Aebersold's Degrees
- PhD Biochemistry University of Basel
Why Is Ruedi Aebersold Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rudolf Aebersold is a Swiss biologist, regarded as a pioneer in the fields of proteomics and systems biology. He has primarily researched techniques for measuring proteins in complex samples, in many cases via mass spectrometry. Ruedi Aebersold is a professor of Systems biology at the Institute of Molecular Systems Biology in ETH Zurich. He was one of the founders of the Institute for Systems Biology in Seattle, Washington, where he previously had a research group.
Ruedi Aebersold's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mass spectrometry-based proteomics (2003) (6395)
- Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. (2002) (4680)
- Quantitative analysis of complex protein mixtures using isotope-coded affinity tags (1999) (4664)
- A statistical model for identifying proteins by tandem mass spectrometry. (2003) (4412)
- Molecular characterization of mitochondrial apoptosis-inducing factor (1999) (4165)
- Correlation between Protein and mRNA Abundance in Yeast (1999) (3867)
- Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis* (2012) (2087)
- Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. (2001) (2037)
- Mass Spectrometry and Protein Analysis (2006) (1913)
- On the Dependency of Cellular Protein Levels on mRNA Abundance (2016) (1760)
- Checkpoint Blockade Cancer Immunotherapy Targets Tumour-Specific Mutant Antigens (2014) (1612)
- A cellular gene encodes scrapie PrP 27-30 protein (1985) (1496)
- Selected reaction monitoring for quantitative proteomics: a tutorial (2008) (1348)
- Mass spectrometry in proteomics. (2001) (1313)
- Mass-spectrometric exploration of proteome structure and function (2016) (1292)
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry (2003) (1292)
- The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data (2013) (1234)
- Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions (2012) (1155)
- Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing (2000) (958)
- Crucial Step in Cholesterol Homeostasis Sterols Promote Binding of SCAP to INSIG-1, a Membrane Protein that Facilitates Retention of SREBPs in ER (2002) (942)
- Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry (2001) (826)
- NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice (2016) (809)
- Smooth Muscle Cell Phenotypic Transition Associated With Calcification: Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers (2001) (805)
- Full Dynamic Range Proteome Analysis of S. cerevisiae by Targeted Proteomics (2009) (780)
- Integrated Genomic and Proteomic Analyses of Gene Expression in Mammalian Cells*S (2004) (777)
- Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly‐available database (2005) (766)
- A common open representation of mass spectrometry data and its application to proteomics research (2004) (764)
- A guided tour of the Trans‐Proteomic Pipeline (2010) (735)
- The quantitative proteome of a human cell line (2011) (732)
- A uniform proteomics MS/MS analysis platform utilizing open XML file formats (2005) (727)
- The minimum information about a proteomics experiment (MIAPE) (2007) (704)
- Analysis of protein complexes using mass spectrometry (2007) (702)
- Proteomics: the first decade and beyond (2003) (700)
- An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development (2007) (687)
- A systematic approach to the analysis of protein phosphorylation (2001) (677)
- Computational prediction of proteotypic peptides for quantitative proteomics (2007) (673)
- Analysis and validation of proteomic data generated by tandem mass spectrometry (2007) (665)
- The PeptideAtlas project (2005) (664)
- Complementary Profiling of Gene Expression at the Transcriptome and Proteome Levels in Saccharomyces cerevisiae*S (2002) (657)
- Interpretation of Shotgun Proteomic Data (2005) (648)
- Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. (1992) (631)
- OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data (2014) (616)
- Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose. (1987) (609)
- Options and considerations when selecting a quantitative proteomics strategy (2010) (598)
- A brain-specific activator of cyclin-dependent kinase 5 (1994) (590)
- The quantitative and condition-dependent Escherichia coli proteome (2015) (546)
- Orm family proteins mediate sphingolipid homeostasis (2010) (544)
- The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor. (1989) (543)
- Reproducible isolation of distinct, overlapping segments of the phosphoproteome (2007) (540)
- Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial (2018) (529)
- The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. (1992) (528)
- PeptideAtlas: a resource for target selection for emerging targeted proteomics workflows (2008) (520)
- Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro (2004) (519)
- CTCF physically links cohesin to chromatin (2008) (517)
- Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells (2012) (500)
- Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins (2009) (491)
- Development and validation of a spectral library searching method for peptide identification from MS/MS (2007) (491)
- iProphet: Multi-level Integrative Analysis of Shotgun Proteomic Data Improves Peptide and Protein Identification Rates and Error Estimates* (2011) (487)
- High-throughput generation of selected reaction-monitoring assays for proteins and proteomes (2010) (468)
- The Need for Guidelines in Publication of Peptide and Protein Identification Data (2004) (465)
- Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions (1992) (460)
- Rewiring of Genetic Networks in Response to DNA Damage (2010) (458)
- Mass spectrometry in high-throughput proteomics: ready for the big time (2010) (456)
- Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling (2013) (455)
- Probing Native Protein Structures by Chemical Cross-linking, Mass Spectrometry, and Bioinformatics* (2010) (451)
- An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data. (2008) (449)
- mProphet: automated data processing and statistical validation for large-scale SRM experiments (2011) (448)
- How many human proteoforms are there? (2018) (440)
- Applying mass spectrometry-based proteomics to genetics, genomics and network biology (2009) (433)
- Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach (2012) (432)
- Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach* (2014) (430)
- A High-Confidence Human Plasma Proteome Reference Set with Estimated Concentrations in PeptideAtlas* (2011) (428)
- Identification of cross-linked peptides from large sequence databases (2008) (409)
- Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans (2009) (408)
- OpenMS: a flexible open-source software platform for mass spectrometry data analysis (2016) (405)
- Proteome Organization in a Genome-Reduced Bacterium (2009) (401)
- A natural killer cell granule protein that induces DNA fragmentation and apoptosis (1992) (386)
- Proteomics Analysis of Cellular Response to Oxidative Stress (2002) (382)
- Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry (2012) (381)
- Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins (1992) (381)
- Scoring proteomes with proteotypic peptide probes (2005) (373)
- Electroblotting onto activated glass. High efficiency preparation of proteins from analytical sodium dodecyl sulfate-polyacrylamide gels for direct sequence analysis. (1986) (367)
- Mass spectrometry based targeted protein quantification: methods and applications. (2009) (366)
- Mass spectrometric approaches for the identification of gel‐separated proteins (1995) (358)
- Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition (2013) (357)
- Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry (2002) (354)
- Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry. (2003) (351)
- SuperHirn – a novel tool for high resolution LC‐MS‐based peptide/protein profiling (2007) (349)
- Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry (2016) (346)
- A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A (2004) (337)
- The study of macromolecular complexes by quantitative proteomics (2003) (336)
- A repository of assays to quantify 10,000 human proteins by SWATH-MS (2014) (335)
- Mass spectrometry-based proteomics and network biology. (2012) (334)
- Identification of Flow-dependent Endothelial Nitric-oxide Synthase Phosphorylation Sites by Mass Spectrometry and Regulation of Phosphorylation and Nitric Oxide Production by the Phosphatidylinositol 3-Kinase Inhibitor LY294002* (1999) (333)
- Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. (2009) (330)
- The Human Proteome Project: Current State and Future Direction (2011) (328)
- The complete structure of the 55S mammalian mitochondrial ribosome (2015) (326)
- Targeted proteomic strategy for clinical biomarker discovery (2009) (326)
- A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein*S (2009) (325)
- Cloning and Characterization of a Novel Insulin-regulated Membrane Aminopeptidase from Glut4 Vesicles (*) (1995) (320)
- Protein Identification False Discovery Rates for Very Large Proteomics Data Sets Generated by Tandem Mass Spectrometry* (2009) (316)
- Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry (2004) (314)
- Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines. (2016) (308)
- Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps (2015) (304)
- Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast (2010) (302)
- Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags. (2002) (301)
- Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase (2014) (301)
- Serum‐stimulated, rapamycin‐sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI (2000) (298)
- A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis (2013) (297)
- Architecture and conformational switch mechanism of the ryanodine receptor (2014) (294)
- Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system (2013) (294)
- On the development of plasma protein biomarkers. (2011) (292)
- A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients (1998) (285)
- Quantification of mRNA and protein and integration with protein turnover in a bacterium (2011) (284)
- A Mass Spectrometric-Derived Cell Surface Protein Atlas (2015) (282)
- Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry (2005) (281)
- The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome (2012) (281)
- High throughput protein characterization by automated reverse‐phase chromatography/electrospray tandem mass spectrometry (1998) (279)
- Purification and Identification of Secreted Oxidative Stress-induced Factors from Vascular Smooth Muscle Cells* (2000) (279)
- An integrated workflow for charting the human interaction proteome: insights into the PP2A system (2009) (279)
- False discovery rate estimation for cross-linked peptides identified by mass spectrometry (2012) (277)
- ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA Damage (2010) (277)
- Building high-quality assay libraries for targeted analysis of SWATH MS data (2015) (276)
- Solid-phase extraction of N-linked glycopeptides (2007) (271)
- Quantitative variability of 342 plasma proteins in a human twin population (2015) (269)
- A high-quality catalog of the Drosophila melanogaster proteome (2007) (268)
- Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis (2013) (267)
- Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation (2015) (267)
- Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome (2016) (264)
- A systematic approach to modeling, capturing, and disseminating proteomics experimental data (2003) (262)
- Large-scale quantitative assessment of different in-solution protein digestion protocols reveals superior cleavage efficiency of tandem Lys-C/trypsin proteolysis over trypsin digestion. (2012) (259)
- Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition (2013) (257)
- The molecular architecture of the eukaryotic chaperonin TRiC/CCT. (2012) (256)
- Advances in quantitative proteomics via stable isotope tagging and mass spectrometry. (2003) (253)
- Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA (2009) (253)
- Systems proteomics of liver mitochondria function (2016) (253)
- Expanding the Chemical Cross-Linking Toolbox by the Use of Multiple Proteases and Enrichment by Size Exclusion Chromatography* (2012) (251)
- Identification of protein complexes required for efficient sister chromatid cohesion. (2004) (250)
- Building consensus spectral libraries for peptide identification in proteomics (2008) (246)
- Western Blots versus Selected Reaction Monitoring Assays: Time to Turn the Tables? (2013) (243)
- p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1. (1999) (243)
- A multi-center study benchmarks software tools for label-free proteome quantification (2016) (241)
- Molecular architecture of human polycomb repressive complex 2 (2012) (240)
- Mass Spectrometry Based Glycoproteomics—From a Proteomics Perspective* (2010) (238)
- Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics (2012) (238)
- Differential stable isotope labeling of peptides for quantitation and de novo sequence derivation. (2001) (236)
- Mass Spectrometry Applied to Bottom-Up Proteomics: Entering the High-Throughput Era for Hypothesis Testing. (2016) (234)
- Phosphorylation of Nup98 by Multiple Kinases Is Crucial for NPC Disassembly during Mitotic Entry (2011) (232)
- The complete structure of the large subunit of the mammalian mitochondrial ribosome (2014) (231)
- High Sensitivity Detection of Plasma Proteins by Multiple Reaction Monitoring of N-Glycosites*S (2007) (228)
- Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline (2013) (227)
- Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis (2009) (226)
- Yeast Nuclear Extract Contains Two Major Forms of RNA Polymerase II Mediator Complexes* (2001) (224)
- Independent evolution of the prochlorophyte and green plant chlorophyll a/b light-harvesting proteins. (1996) (224)
- Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics (2004) (221)
- Comparative Functional Analysis of the Caenorhabditis elegans and Drosophila melanogaster Proteomes (2009) (220)
- Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex (2013) (216)
- Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population (2014) (216)
- A database of mass spectrometric assays for the yeast proteome (2008) (216)
- PhosphoPep—a database of protein phosphorylation sites in model organisms (2008) (215)
- Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70. (1994) (213)
- ProbID: A probabilistic algorithm to identify peptides through sequence database searching using tandem mass spectral data (2002) (205)
- Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. (1994) (204)
- Gene Expression Analyzed by High-resolution State Array Analysis and Quantitative Proteomics (2004) (204)
- Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations (2011) (204)
- Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor–mediated lipid raft dynamics (2006) (203)
- Beyond ATM: The protein kinase landscape of the DNA damage response (2011) (203)
- Architecture of the large subunit of the mammalian mitochondrial ribosome (2013) (201)
- Quantitative measurements of N‐linked glycoproteins in human plasma by SWATH‐MS (2013) (201)
- The Implications of Proteolytic Background for Shotgun Proteomics*S (2007) (200)
- ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity (1995) (199)
- Targeted Quantitative Analysis of Streptococcus pyogenes Virulence Factors by Multiple Reaction Monitoring*S (2008) (199)
- PhosphoPep—a phosphoproteome resource for systems biology research in Drosophila Kc167 cells (2007) (199)
- A Human Proteome Detection and Quantitation Project* (2009) (198)
- Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70 (*) (1995) (197)
- Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases (2009) (197)
- Mass spectrometry supported determination of protein complex structure. (2013) (196)
- Advances in protein complex analysis using mass spectrometry (2005) (195)
- TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer. (2016) (195)
- A Software Suite for the Generation and Comparison of Peptide Arrays from Sets of Data Collected by Liquid Chromatography-Mass Spectrometry*S (2005) (193)
- A Novel, Evolutionarily Conserved Protein Phosphatase Complex Involved in Cisplatin Sensitivity*S (2005) (193)
- High Throughput Quantitative Analysis of Serum Proteins Using Glycopeptide Capture and Liquid Chromatography Mass Spectrometry *S (2005) (193)
- Multi-omic measurements of heterogeneity in HeLa cells across laboratories (2019) (192)
- A High-Density Map for Navigating the Human Polycomb Complexome. (2016) (192)
- Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosis. (2015) (192)
- Approaching complete peroxisome characterization by gas‐phase fractionation (2002) (192)
- Unequivocal demonstration of the involvement of a glutamate residue as a nucleophile in the mechanism of a retaining glycosidase (1990) (189)
- Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape. (2005) (189)
- Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS (2013) (187)
- Quantitative proteomic analysis of Myc oncoprotein function (2002) (186)
- PASSEL: The PeptideAtlas SRMexperiment library (2012) (185)
- Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. (1986) (185)
- Analysis, statistical validation and dissemination of large-scale proteomics datasets generated by tandem MS. (2004) (184)
- Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts (1991) (183)
- Dynamic Spectrum Quality Assessment and Iterative Computational Analysis of Shotgun Proteomic Data (2006) (183)
- Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes (2014) (182)
- Quantitative proteome analysis using isotope-coded affinity tags and mass spectrometry (2006) (179)
- An integrated mass spectrometric and computational framework for the analysis of protein interaction networks (2007) (178)
- diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition (2020) (177)
- Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. (2005) (177)
- Using data‐independent, high‐resolution mass spectrometry in protein biomarker research: Perspectives and clinical applications (2015) (176)
- B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein. (1994) (174)
- The protein interaction landscape of the human CMGC kinase group. (2013) (173)
- Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry* (2015) (172)
- Characterization of a DNA exit gate in the human cohesin ring (2014) (171)
- The standard protein mix database: a diverse data set to assist in the production of improved Peptide and protein identification software tools. (2008) (171)
- Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex (2014) (170)
- Glycoproteomic Analysis of Prostate Cancer Tissues by SWATH Mass Spectrometry Discovers N-acylethanolamine Acid Amidase and Protein Tyrosine Kinase 7 as Signatures for Tumor Aggressiveness* (2014) (169)
- Generating and navigating proteome maps using mass spectrometry (2010) (169)
- Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. (2003) (167)
- Proteome Analysis of Legionella Vacuoles Purified by Magnetic Immunoseparation Reveals Secretory and Endosomal GTPases (2009) (166)
- Perspectives of targeted mass spectrometry for protein biomarker verification. (2009) (166)
- Optimization of the isotope-coded affinity tag-labeling procedure for quantitative proteome analysis. (2001) (166)
- Complementary Analysis of the Mycobacterium tuberculosis Proteome by Two-dimensional Electrophoresis and Isotope-coded Affinity Tag Technology * (2004) (166)
- Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. (1994) (165)
- Two-dimensional Blue Native/SDS Gel Electrophoresis of Multi-Protein Complexes from Whole Cellular Lysates (2004) (163)
- The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis. (2013) (162)
- Quantitative proteomics: challenges and opportunities in basic and applied research (2017) (162)
- Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays. (2016) (162)
- Identification of CDK2 substrates in human cell lysates (2008) (160)
- Ceramide profiling of complex lipid mixtures by electrospray ionization mass spectrometry. (1997) (160)
- Increased Selectivity, Analytical Precision, and Throughput in Targeted Proteomics (2010) (160)
- Data analysis and bioinformatics tools for tandem mass spectrometry in proteomics. (2008) (159)
- Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent‐resistant membrane domains (2001) (159)
- A microfabricated device for rapid protein identification by microelectrospray ion trap mass spectrometry. (1997) (159)
- Visual proteomics of the human pathogen Leptospira interrogans (2009) (158)
- Building ProteomeTools based on a complete synthetic human proteome (2017) (158)
- Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid (2005) (157)
- The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays. (2017) (156)
- Identification of TFB5, a new component of general transcription and DNA repair factor IIH (2004) (156)
- Corrigendum: Identification of cross-linked peptides from large sequence databases (2008) (156)
- Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane (2004) (156)
- Protein kinase D at the Golgi controls NLRP3 inflammasome activation (2017) (155)
- RNF168 promotes noncanonical K27 ubiquitination to signal DNA damage. (2015) (155)
- Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster (2009) (155)
- Protein identification by solid phase microextraction—capillary zone electrophoresis—microelectrospray—tandem mass spectrometry (1996) (154)
- An automated pipeline for high-throughput label-free quantitative proteomics. (2013) (154)
- Advances in Proteome Analysis by Mass Spectrometry* (2001) (154)
- Reproducible and Consistent Quantification of the Saccharomyces cerevisiae Proteome by SWATH-mass spectrometry* (2015) (154)
- Regulation of yeast central metabolism by enzyme phosphorylation (2012) (153)
- Analysis of α-Synuclein-associated Proteins by Quantitative Proteomics*[boxs] (2004) (152)
- Cancer genetics-guided discovery of serum biomarker signatures for diagnosis and prognosis of prostate cancer (2011) (149)
- Cross-Link Guided Molecular Modeling with ROSETTA (2013) (149)
- Analysis of dilute peptide samples by capillary zone electrophoresis. (1990) (148)
- Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution (2010) (147)
- TRIC: an automated alignment strategy for reproducible protein quantification in targeted proteomics (2016) (147)
- Proteomic Profiling of Pancreatic Cancer for Biomarker Discovery* (2005) (147)
- Applications of targeted proteomics in systems biology and translational medicine (2015) (147)
- Direct identification of ligand-receptor interactions on living cells and tissues (2012) (146)
- Protein Significance Analysis in Selected Reaction Monitoring (SRM) Measurements* (2011) (146)
- Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli. (1992) (145)
- Approaches to labeling and identification of active site residues in glycosidases (1995) (145)
- Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. (2016) (144)
- Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus. (2007) (142)
- Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae (2011) (141)
- Quantitative interaction proteomics using mass spectrometry (2009) (141)
- Structures of human PRC2 with its cofactors AEBP2 and JARID2 (2018) (141)
- Molecular Architecture of the ATP-Dependent Chromatin-Remodeling Complex SWR1 (2013) (140)
- The Direct Recruitment of BLNK to Immunoglobulin α Couples the B-Cell Antigen Receptor to Distal Signaling Pathways (2002) (140)
- Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways (2003) (140)
- Reporting Protein Identification Data (2006) (140)
- Analysis of membrane proteins by two‐dimensional electrophoresis: Comparison of the proteins extracted from normal or Plasmodium falciparum ‐ infected erythrocyte ghosts (1999) (139)
- Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. (1991) (138)
- Parallel, quantitative measurement of protein binding to a 120-element double-stranded DNA array in real time using surface plasmon resonance microscopy. (2004) (138)
- Proteomics meets the scientific method (2013) (137)
- High Throughput Proteome Screening for Biomarker Detection* (2005) (137)
- An Integrated, Directed Mass Spectrometric Approach for In-depth Characterization of Complex Peptide Mixtures *S (2008) (136)
- Standard guidelines for the chromosome-centric human proteome project. (2012) (136)
- Statistical control of peptide and protein error rates in large-scale targeted DIA analyses (2017) (136)
- Proteome analysis: Biological assay or data archive? (1998) (136)
- Perspective: a program to improve protein biomarker discovery for cancer. (2005) (136)
- Chemical probes and tandem mass spectrometry: a strategy for the quantitative analysis of proteomes and subproteomes. (2004) (134)
- Association of Two Novel Proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA Editing Complex (2001) (132)
- Human Plasma PeptideAtlas (2005) (131)
- RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily (1998) (131)
- The pros and cons of peptide-centric proteomics (2010) (131)
- SPARC from Olfactory Ensheathing Cells Stimulates Schwann Cells to Promote Neurite Outgrowth and Enhances Spinal Cord Repair (2007) (130)
- Coordinate regulation of energy transduction modules in Halobacterium sp. analyzed by a global systems approach (2002) (128)
- The receptor for yolk lipoprotein deposition in the chicken oocyte. (1991) (128)
- Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex (2018) (127)
- N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1). (2004) (127)
- Estimation of Absolute Protein Quantities of Unlabeled Samples by Selected Reaction Monitoring Mass Spectrometry* (2011) (125)
- Proteomic analysis identifies that 14-3-3ζ interacts with β-catenin and facilitates its activation by Akt (2004) (125)
- Xwalk: computing and visualizing distances in cross-linking experiments (2011) (124)
- A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability (2017) (124)
- Tyrosyl phosphorylation and activation of MAP kinases by p56lck. (1992) (123)
- Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs (2012) (123)
- Microspotting streptavidin and double-stranded DNA arrays on gold for high-throughput studies of protein-DNA interactions by surface plasmon resonance microscopy. (2004) (122)
- Peptide-Centric Proteome Analysis: An Alternative Strategy for the Analysis of Tandem Mass Spectrometry Data* (2015) (122)
- Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2. (2015) (122)
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- A new isotype sequence (V kappa 27) of the variable region of kappa-light chains from a mouse hybridoma-derived anti-(streptococcal group A polysaccharide) antibody containing an additional cysteine residue. Application of the dimethylaminoazobenzene isothiocyanate technique for the isolation of pep (1983) (6)
- Targeted protein quantification using sparse reference labeling (2014) (6)
- Deciphering MET‐dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics (2020) (6)
- reaction-monitoring assays for proteins and proteomes (2012) (6)
- Characterization of an activated ribosomal S6 kinase variant from maturing sea star oocytes: Association with phosphatase 2A and substrate specificity (1999) (6)
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- Creating, tailoring and using one-dimensional interfaces in two-dimensional films (1998) (5)
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- Nucleotide-amino acid π-stacking interactions initiate photo cross-linking in RNA-protein complexes (2022) (5)
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- Structural requirements for photo-induced RNA-protein cross-linking (2021) (5)
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- Integration of transcriptome, proteome and phosphoproteome data elucidates the genetic control of molecular networks (2019) (5)
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- The impact of genomic variation on protein phosphorylation states and regulatory networks (2022) (4)
- characterization of complex peptide mixtures (2008) (4)
- All Driven by Energy Demand? Integrative Comparison of Metabolism of Enterococcus faecalis Wildtype and a Glutamine Synthase Mutant (2021) (4)
- Murine VK25 isotype sequence: monoclonal antibody 2S1.3 specific for the group A streptococcal polysaccharide. (1982) (4)
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- The GTPase Nog1 couples polypeptide exit tunnel quality control with ribosomal stalk assembly (2018) (4)
- Automated SWATH Data Analysis Using Targeted Extraction of Ion Chromatograms (2016) (4)
- Rapid profiling of protein complex re-organization in perturbed systems (2021) (4)
- Single Nucleotide Resolution RNA–Protein Cross-Linking Mass Spectrometry: A Simple Extension of the CLIR-MS Workflow (2021) (4)
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- A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer. (2019) (4)
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- On the feasibility of deep learning applications using raw mass spectrometry data (2021) (4)
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- Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes (2014) (4)
- Reduced CXCL4/PF4 expression as a driver of increased human hematopoietic stem and progenitor cell proliferation in polycythemia vera (2021) (3)
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- Identification of the target of monoclonal antibody A6H as dipeptidyl peptidase IV/CD26 by LC MS\MS. (2001) (3)
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- Identification of T-cell receptor a-chain genes in the chicken (2004) (3)
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- Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs (2012) (3)
- Murine V kappa 21A isotype sequence: monoclonal antibody 50S10.1 specific for the group A streptococcal polysaccharide. (1984) (3)
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- A Novel Approach to Isolation of Proteins for Microsequence Analysis: Electroblotting Onto Activated Glass (1987) (3)
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- PRIME-XS, a European Infrastructure for Proteomics (2014) (3)
- Analysis of MHC immunopeptidomes using mass (2015) (3)
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- Tandem mass spectrometry database searching (2005) (3)
- [From genome to proteome--aim of human proteomics]. (2004) (3)
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- A Proteomic Connectivity Map. (2018) (3)
- Statistical elimination of spectral features with large between-run variation enhances quantitative protein-level conclusions in experiments with data-independent spectral acquisition (2015) (2)
- Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9. (2020) (2)
- Integrative analysis allows a global and precise identification of functional miRNA target genes in mESCs (2021) (2)
- A MODEL FOR COUPLING CONSECUTIVE STAGE MASS SPECTROMETRY DATA FOR INCREASED PEPTIDE IDENTIFICATION CONFIDENCE* □ S (2007) (2)
- Cancer genetics-guided discovery of serum biomarker signatures for prostate cancer. (2010) (2)
- Bacterium Proteome Organization in a Genome-Reduced (2009) (2)
- Accelerated Protein Biomarker Discovery from FFPE tissue samples using Single-shot, Short Gradient Microflow SWATH MS (2019) (2)
- Characterization of Proteins Separated by Gel Electrophoresis at the Primary Structure Level (1995) (2)
- Sensitive detection and structural characterisation of UV-induced cross-links in protein-RNA complexes using CLIR-MS (2022) (2)
- A Class of Environmental and Endogenous Toxins Induces BRCA 2 Haploinsufficiency and Genome Instability Graphical (2017) (2)
- Mapping protein-RNA interactions with single residue resolution by CLIR-MS/MS (2017) (2)
- growth Molecular basis of Rrn 3-regulated RNA polymerase I initiation and cell (2011) (2)
- mProphet : A general and flexible data model and algorithm for automated SRM data processing and statistical error estimation (2010) (2)
- Targeted Proteomics (2012) (2)
- Erratum: From promising to practical: tools to study networks of neurons (2010) (2)
- Linking genotype and phenotype (2018) (2)
- Two parallel pathways implement robust propionate catabolism and detoxification in mycobacteria (2018) (2)
- Quantitative Protein Analysis by Solid Phase Isotope Tagging and Mass Spectrometry (2004) (2)
- Author Correction: Proteomic and interactomic insights into the molecular basis of cell functional diversity (2020) (2)
- Quantitative proteomics profiling of neoplastic progression of ulcerative colitis: O-0020. (2008) (2)
- Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency (2022) (2)
- Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells (2017) (1)
- Protein technologies and commercial enzymes (2000) (1)
- Mechanotransduction coordinates extracellular matrix protein homeostasis promoting longevity in C. elegans (2022) (1)
- Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase (2014) (1)
- PCfun: a hybrid computational framework for systematic characterization of protein complex function (2022) (1)
- Swath-ms: a new data independent acquisition LC-MS methodology for quantitative complete proteome analysis (2011) (1)
- Synthesis, Evaluation and Application of a Panel of Novel Reagents for Stepwise Degradation of Polypeptides (1995) (1)
- , Systematically Perturbed Metabolic Network Integrated Genomic and Proteomic Analyses of a (2010) (1)
- Abstract 5565: Multi-omic profiling of prostate cancer evolution in 39 patients (2017) (1)
- Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins (2019) (1)
- Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells (2022) (1)
- Systematic quantification of peptides/proteins in urine using selected reaction monitoring (2011) (1)
- Characterization of an Axonal Protein Involved in Myelination (1997) (1)
- Solid-Phase Extraction-Capillary Zone Electrophoresis-Mass Spectrometry Analysis of Low-Abundance Proteins (2001) (1)
- Global and precise identification of functional miRNA targets in mESCs by integrative analysis (2022) (1)
- Faculty Opinions recommendation of Global landscape of HIV-human protein complexes. (2012) (1)
- iProphet: Improved statistical validation of peptide and protein identifications in shotgun proteomics (2011) (1)
- Proteomic and interactomic insights into the molecular basis of cell functional diversity (2020) (1)
- Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring (2013) (1)
- Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success. (2010) (1)
- Quantitative Analysis of Proteomes and Subproteomes by Isotope-Coded Affinity Tag and Solid-Phase Glycoprotein Capture (2005) (1)
- Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization (2022) (1)
- Systematic protein complex profiling and differential analysis from co-fractionation mass spectrometry data (2020) (1)
- Proteomics: Technology and Applications (2003) (1)
- Author Correction: Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex (2018) (1)
- Modulation-dependent effect of microwaves on protein expression in human endothelial cell line EA (2004) (1)
- Structure of the 55S mammalian mitoribosome. (2015) (1)
- The polyQ expansion modulates the configuration and phosphorylation of huntingtin (2019) (1)
- Statistical elimination of spectral features with large between-run variation enhances quantitative protein-level conclusions in experiments with data-independent spectral acquisition (2015) (1)
- Computational Tools for Tandem Mass Spectrometry–Based High-Throughput Quantitative Proteomics (2005) (1)
- Identification of protein abundance changes in biopsy-level hepatocellular carcinoma tissues using PCT-SWATH (2018) (1)
- Author Correction: Artificial intelligence defines protein-based classification of thyroid nodules (2022) (1)
- Systematic Proteomic Analysis Identifies (cid:1) -Site Amyloid Precursor Protein Cleaving Enzyme 2 and 1 (BACE2 and BACE1) Substrates in Pancreatic (cid:1) -Cells (2020) (1)
- Arabidopsis proteome and the mass spectral assay library (2019) (1)
- Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes (2014) (1)
- The Advent of Mass Spectrometry-Based Proteomics in Systems Biology Research (2016) (1)
- PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome (2021) (1)
- Activity Based Protein Profiling Of Human Lung Adenocarcinoma Biopsies (2010) (1)
- Publisher Correction: ChromID identifies the protein interactome at chromatin marks (2020) (1)
- Quantitative proteomic landscapes of primary and recurrent glioblastoma reveal a protumorigeneic role for FBXO2-dependent glioma-microenvironment interactions. (2022) (1)
- The Development of a Facility to Analyze and Synthesize Genes and Proteins (1987) (1)
- Foreword (1997) (1)
- Life, Environmental and Geo Sciences Committee Opinion Paper: The Importance of International Collaboration for Fostering Frontier Research (2014) (1)
- Proteogenomic heterogeneity of localized human prostate cancer progression (2020) (1)
- Combinatorial diversity in the generation of antibody molecules. The complete amino-acid sequence of the variable domain of a monoclonal anti-streptococcal group A polysaccharide antibody. (1986) (1)
- SWATH-MS co-expression profiles reveal paralogue interference in protein complex evolution (2020) (1)
- Activity-Based Biomarker Identification In Non-Small Cell Lung Cancer (NSCLC) (2011) (1)
- Regarding the size of Rh proteins [letter] (1991) (1)
- 7q11.23 CNV alters protein synthesis and REST-mediated neuronal intrinsic excitability (2022) (1)
- Faculty Opinions recommendation of An integrated map of genetic variation from 1,092 human genomes. (2013) (1)
- FOCUS: PROTEOMICS Quantitative Proteomic Analysis of Chromatin-Associated Factors (2011) (0)
- A process for the isolation and labeling of sample molecules (2002) (0)
- Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies (2023) (0)
- Key molecular interactions between the amyloid beta peptide and apolipoprotein E isoforms revealed by chemical crosslinking/mass spectrometry (2014) (0)
- Delayed effects of transcriptional responses in Mycobacterium tuberculosis exposed to nitric oxide suggest other mechanisms involved in survival (2017) (0)
- Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 (2015) (0)
- Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 (2011) (0)
- Systematic proteomic profiling of the human Polycomb interactome (2016) (0)
- Regions implicated in inter N- and C-terminal domain interaction of the three major isoforms of ApoE interacts with the amyloid beta peptide of Alzheimer disease (2016) (0)
- Involvement of mismatch repair proteins in activation-induced deaminase-mediated antibody diversification (2008) (0)
- Site-Specific, Stable Isotope Labeling of Cysteinyl Peptides in Complex Peptide Mixtures (2006) (0)
- ChromID identifies the protein interactome at chromatin marks (2020) (0)
- Algorithms for Constructing Signal Maps be- tween Mass Spectrometry Experiments (2003) (0)
- Proteomic-based stratification of intermediate-risk prostate cancer patients (2023) (0)
- Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State (2018) (0)
- Mass Spectrometric Exploration of the Biochemical Basis of Living Systems. (2019) (0)
- The pros and cons of peptide-centric (2010) (0)
- Integrative solution structure of a PTBP1-viral IRES complex reveals strong compaction and ordering with residual conformational flexibility (2022) (0)
- Proteomics-Metabolomics Picture of Cellular Metabolism (2012) (0)
- The role of MET in tumor resistance to radiation therapy: a phosphoproteomic approach (2016) (0)
- Abstract 5576: Activity based protein profiling of human lung adenocarcinoma biopsies (2010) (0)
- AN INTEGRATED EXPERIMENTAL WORKFLOW TO INCREASE THROUGHPUT AND DATA ROBUSTNESS FOR ANALYSIS OF MAMMALIAN PROTEIN INTERACTION NETWORKS (2010) (0)
- Methods in Enzymology,Volumes 270 and 271,High-Resolution Separation and Analysis of Biological Macromolecules.Edited by Barry L. Karger and William S. Hancock (1997) (0)
- Short Article N-Acetylation and Ubiquitin-Independent (2004) (0)
- Protein Complex Identification: Analysis of the human phosphatase system PP2A (2010) (0)
- Abstract B60: Perturbation biology of colorectal cancer organoids reveals patient-specific signaling rewiring and interference with immunity (2020) (0)
- Rapid and reproducible proteotype acquisition from biopsy level samples (2016) (0)
- Abstract A52: Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics reveals Ser1016 as a novel MET phosphosite that regulates cellular response to irradiation (2020) (0)
- Encoding the observed human plasma proteome in spectral libraries (2007) (0)
- PCprophet: a framework for protein complex prediction and differential analysis using proteomic data (2021) (0)
- Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS (2012) (0)
- Mapping and measuring molecular networks in cells (2010) (0)
- An integrated cross-species approach for the discovery of serum-based diagnostic biomarkers of PDAC using a genetically engineered murine model (GEMM). (2012) (0)
- hTRiC-hPFD Class6 (2019) (0)
- Mapping the protein-protein interactions of Drosophila melanogaster (2009) (0)
- Integrated-omics analysis uncovers a fundamental hypoxia-driven mechanism of breast cancer progression (2014) (0)
- Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry (2017) (0)
- Development of a spectral library building tool and re-analysis of Human Plasma PeptideAtlas datasets using spectral searching (2007) (0)
- e- Blood Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells (2010) (0)
- Science Signaling Pawson and Rune Linding ( 28 July 2009 ) (2009) (0)
- Network Biology: Data Requirements and Biological Consequences (2012) (0)
- M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments. (2023) (0)
- Author response: Huntingtin’s spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function (2015) (0)
- hTRiC-hPFD Class5 (2019) (0)
- Faculty Opinions recommendation of Analysis of serum proteomic patterns for early cancer diagnosis: drawing attention to potential problems. (2004) (0)
- Resource Human SRMAtlas : A Resource of Targeted Assays to Quantify the Complete Human Proteome Graphical Abstract Highlights (2016) (0)
- A Web Resource for Improved Analysis of AP-MS Protein Interaction Data. (2013) (0)
- Chemical crosslinking/mass spectrometry defines key molecular interactions between apolipoprotein E and amyloid beta peptide (2014) (0)
- Generation of a zebrafish SWATH-MS spectral library to quantify 10,000 proteins (2019) (0)
- cell growth Molecular basis of Rrn 3-regulated RNA polymerase I initiation and (2011) (0)
- Faculty Opinions recommendation of Epistasis as the primary factor in molecular evolution. (2012) (0)
- A high quality human plasma proteome available in the PeptideAtlas (2009) (0)
- Toward the structure of the apoE-amyloid beta complex (2015) (0)
- Estimating false discovery rates in spectral searching using decoy spectral libraries (2007) (0)
- Towards a systematic characterization of protein complex function: a natural language processing and machine-learning framework (2021) (0)
- The author file (2010) (0)
- Author Correction: Arabidopsis proteome and the mass spectral assay library (2021) (0)
- Proteomanalyse (2021) (0)
- Author response: An open-source computational and data resource to analyze digital maps of immunopeptidomes (2015) (0)
- Phosphorylation‐linked complex profiling identifies assemblies required for Hippo signal integration (2023) (0)
- High-throughput reversed-phase microcapillary liquid chromatographic system as a nanoscale electrospray ionization source for tandem mass spectrometry (2002) (0)
- Structure of the small subunit of the mammalian mitoribosome (2015) (0)
- System-wide quantitative proteomics of the metabolic syndrome in mice: genotypic and dietary effects (2016) (0)
- in cisplatin sensitivity (2005) (0)
- hTRiC-hPFD Class3 (2019) (0)
- Multi-omic measurements of heterogeneity in HeLa cells across laboratories (2019) (0)
- The Proteotype Model (2019) (0)
- Annotation of the yeast Proteome with PeptideAtlas (2006) (0)
- Author Correction: Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex (2018) (0)
- Publisher Correction: OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data (2020) (0)
- Abstract 6482: Activity based protein profiling by SWATH/DIA-MS mode (ABPP-SWATH/DIA-MS) from OCT-embedded tissues biopsies reveals lung tumor-specific protease profiles (2020) (0)
- Highly multiplexed protein profiling across large sets of samples: a comparison of DIA/HRM-MS acquisition with shotgun LC-MS/MS using a "gold standard sample set" (2015) (0)
- Mapping and measuring proteomes (2011) (0)
- Gene Expression: Basic Concepts (2008) (0)
- AN INTEGRATED EXPERIMENTAL WORKFLOW TO INCREASE THROUGHPUT AND DATA ROBUSTNESS FOR ANALYSIS OF MAMMALIAN PROTEIN INTERACTION NETWORKS (2011) (0)
- 35: Personalised proteotypes and their association with disease (2014) (0)
- A new class of protein biomarkers based on subcellular distribution: application to a mouse liver cancer model (2019) (0)
- Proteomic Dynamics of Breast Cancers Identifies Potential Therapeutic Protein Targets (2022) (0)
- 39S large subunit of the porcine mitochondrial ribosome (2013) (0)
- Evidence of N- and C-terminal interaction of the three major isoforms of apoE with the Aβ peptide of the Alzheimer Disease (2016) (0)
- Franz Herzog Cross-Linking and Mass Spectrometry Structural Probing of a Protein Phosphatase 2 A Network by Chemical (2012) (0)
- Time-controlled Transcardiac Perfusion Crosslinking (tcTPC): A Novel Tool for the In Vivo Study of Protein Interactions in Complex Tissues (2003) (0)
- hTRiC-hPFD Class2 (2019) (0)
- MLL1 minimal catalytic complex is a dynamic conformational ensemble susceptible to pharmacological allosteric disruption (2018) (0)
- Faculty Opinions recommendation of The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. (2011) (0)
- SECAT: Quantifying differential protein-protein interaction states by network-centric analysis (2019) (0)
- Genetic variability and the quantitative proteome (95.3) (2014) (0)
- INTEGRATED MULTI-OMIC ANALYSIS OF A RARE INBORN ERROR OF METABOLISM (2022) (0)
- Faculty Opinions recommendation of Chromosome organization by a nucleoid-associated protein in live bacteria. (2011) (0)
- La dinámica de los estados de fosforilación de las vías HOG y de las feromonas en levaduras (2012) (0)
- Faculty Opinions recommendation of Live mammalian cell arrays. (2013) (0)
- 5 Towards a high throughput platform for quantitative serum protein profiling (2004) (0)
- 83 Mass Spectrometric Strategies for Protein Biomarker Discovery and Validation (2012) (0)
- Supporting Online Material for Rewiring of Genetic Networks in Response to DNA Damage (2010) (0)
- Structure of the large subunit of the mammalian mitoribosome, part 1 of 2 (2014) (0)
- Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2 (2018) (0)
- 1311 Quantitative analysis of Pten conditional knockout mouse proteome reveals significant prognostic biomarkers for survival in metastatic castration resistant prostate cancer (CRPC) (2009) (0)
- DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes (2023) (0)
- Science Signaling Podcast: 21 December 2010 (2010) (0)
- Computational Mass Spectrometry (Dagstuhl Seminar 13491) (2013) (0)
- Publisher Correction: ChromID identifies the protein interactome at chromatin marks (2020) (0)
- 318 The ATM-mediated DNA damage response: the system and the pathways (2010) (0)
- Toward the ApoE-Amyloid beta complex structure: a therapeutic target in Alzheimer disease (2014) (0)
- Computational Mass Spectrometry (Dagstuhl Seminar 15351) (2015) (0)
- Author response: The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers (2019) (0)
- The PeptideAtlas as a tool for targeted proteomics (2008) (0)
- Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine (2014) (0)
- Structure of the ryanodine receptor at resolution of 6.1 A in closed state (2014) (0)
- ATAQS Computational Software Tool for High Throughput Transition Optimization and Validation for SRM (2009) (0)
- Murine V kappa 25 and V kappa 27 amino-acid sequences of C57B1/6 origin: monoclonal antibodies 17S29.1 and 22S25.1 specific for the group A-streptococcal polysaccharide. (1984) (0)
- Improved support for targeted proteomics workflows in PeptideAtlas (2009) (0)
- Faculty Opinions recommendation of Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations. (2011) (0)
- 1430 POSTER Quantitative Analysis of PTEN-dependent Glycoprotein Patterns Reveals Predictive Biomarker Signature for Response of Human Patients to Docetaxel Therapy in Metastatic Castration Resistant Prostate Cancer (mCRPC) (2011) (0)
- Systems pharmacology and quantitative proteomics for developing targeted triple therapy (2017) (0)
- Reduced CXCL4/PF4 expression as a driver of increased human hematopoietic stem and progenitor cell proliferation in polycythemia vera (2021) (0)
- MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans (2019) (0)
- Molecular basis of AKAP79 regulation by calmodulin (2017) (0)
- Integrative structural Investigation on the architecture of human Importin4_histone H3/H4_Asf1a complex and its histone H3 tail binding (2017) (0)
- P-003: Detection of bacterial and host proteins from a single colonic biopsy sample by a new mass spectrometry-based assay in pediatric ulcerative colitis (2014) (0)
- High Sensitivity Analysis of Amino Acids, Peptides and Proteins by Color Labelling Techniques (1985) (0)
- Abundance-dependent proteomic analysis by mass spectrometry (2002) (0)
- Proteomic analysis identifies that 14-3-3 (cid:1) interacts with (cid:2) -catenin and facilitates its activation by Akt (2004) (0)
- Phosphorylation-based signaling networks mediate the effect of ligand affinity of the activation of naive primary T-cells (2011) (0)
- Proteotyping Gene Dosage Effects in Genetic Diseases (2017) (0)
- An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies (2022) (0)
- From mice to men: A novel serum signature for prostate cancer diagnosis (2008) (0)
- Faculty Opinions recommendation of Evolution of increased complexity in a molecular machine. (2012) (0)
- New functionality for the Trans-Proteomic Pipeline: tools for analysis of proteomics data (2009) (0)
- Faculty Opinions recommendation of Phenotypic landscape of a bacterial cell. (2011) (0)
- 4058 Enhanced efficiency of large-scale clinical proteomic studies: when less is more (2020) (0)
- efficient analysis of large LC-MS/MS and SWATH-MS datasets (2014) (0)
- Abstract C28: Discovery of new protein biomarkers for prostate cancer diagnosis using a Pten‐dependent mouse model and their validation in human patients (2009) (0)
- Protein Chemistry and the Biotechnology of the Future (1989) (0)
- New developments for open-source shotgun proteomics analysis with the Trans-Proteomic Pipeline (2008) (0)
- A device for the quantitative collection of derivatives generated by chemical protein sequence analysis (1993) (0)
- Human TRiC/CCT complex with reovirus outer capsid protein sigma-3 (2021) (0)
- hTRiC-hPFD Class4 (2019) (0)
- Structural insights into the architecture of human Importin 4 _ histone H 3 / H 4 _ Asf 1 a complex and its histone H 3 tail binding (2017) (0)
- Chapter 2:The Coupling of Microfabricated Fluidic Devices with Electrospray Ionization Mass Spectrometers (2008) (0)
- Author Correction: Proteomic and interactomic insights into the molecular basis of cell functional diversity (2020) (0)
- Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen (2021) (0)
- Structure of the ryanodine receptor at resolution of 8.5 A in partially open state (2014) (0)
- Structure-function relationships in two cellulase families (1991) (0)
- iProphet: A new tool for combining PeptideProphet results from multiple search engines improves spectrum validation (2008) (0)
- More Efficient Tissue Lysis and Protein Digestion with Lower Concentration of Denaturant Using Pressure Cycling Technology (2015) (0)
- "Personalized health" : report to discuss options and frame for a new Swiss initiative (2014) (0)
- Large-scale changes of molecular network states explain complex traits (2022) (0)
- High precision profiling of glycopeptides using HPLC-CHIP/MS TOF (2005) (0)
- Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex (2018) (0)
- Faculty Opinions recommendation of Analysis of kinase gene expression patterns across 5681 human tissue samples reveals functional genomic taxonomy of the kinome. (2011) (0)
- A human plasma proteome in the PeptideAtlas with estimated protein concentrations (2009) (0)
- Comprehensive proteome analysis of skeletal muscle in cachexia and age-related sarcopenia: a pilot comparison of in vivo and in vitro models a (2017) (0)
- Nano-LC MALDI-QTOF-MS for the analysis of complex ICAT labeled protein mixtures (2002) (0)
- UniPep, a database for human N-linked glycosites (2006) (0)
- The structure and symmetry of radial spoke protein complex in Chlamydomonas flagella. (2020) (0)
- Compositions and method for quantifying serumglykoproteinen (2005) (0)
- Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer (2018) (0)
- Abstract 4934: Modified SWATH MS analysis of serine hydrolase activity in lung adenocarcinoma (2019) (0)
- Faculty Opinions recommendation of Modular decomposition of protein-protein interaction networks. (2004) (0)
- hTRiC-hPFD Class1 (No PFD) (2019) (0)
- P2.03-13 SWATH MS Analysis of Serine Hydrolase Activity in Human Lung Adenocarcinoma for Biomarker Discovery (2018) (0)
- Abstract 1887: Discrimination of aggressive tumor profiles in lung adenocarcinomas using activity based protein profiling by SWATH/DIA-MS mode (2022) (0)
- Absolute protein quantification estimated by spectral counting using large datasets in PeptideAtlas (2008) (0)
- Leukocyte Protein Expressed in Transformed Human Fibroblasts (0)
- Separation of blood microsamples by exploiting sedimentation at the microscale (2018) (0)
- Convergent network effects along the axis of gene expression during prostate cancer progression (2020) (0)
- Rapid and quantitative proteome analysis and corresponding methods (2001) (0)
- Chemical crosslinking/mass spectrometry to map the amyloid beta peptide binding region on apolipoprotein E isoforms (2014) (0)
- ApoE N- and C-terminal domain interacting interface is involved in amyloid beta binding: Insights from cross-linking mass spectrometry (2017) (0)
- Chemical crosslinking/mass spectrometry to reveal the amyloid beta peptide binding motif on apolipoprotein E (2015) (0)
- Report from Dagstuhl Seminar 13491 Computational Mass Spectrometry (2014) (0)
- Molecular anatomy of the human pathogen Leptospira interrogans (2008) (0)
- Unraveling the ApoE-Amyloid beta complex structure by chemical crosslinking coupled to mass spectrometry and bioinformatics (2014) (0)
- ProDac (Proteomics data collection); Coordinated action within the 6th EU framework programme (2006) (0)
- Structure of the large subunit of the mammalian mitoribosome, part 2 of 2 (2014) (0)
- FRI-297-Trans-signaling blockade induces mature-onset obesity and insulin resistance in mice via suppression of PPARalpha (2019) (0)
- Deep Domain Adversarial Neural Network for the Deconvolution of Cell Type Mixtures in Tissue Proteome Profiling (2023) (0)
- The proteome: Analysis and utility (2002) (0)
- Time course RNA-seq of Mycobacterium tuberculosis exposed to nitric oxide (2017) (0)
- Comprehensive proteome analysis of muscle composition and development in seniors (2017) (0)
- O-0020: Quantitative proteomics profiling of neoplastic progression of ulcerative colitis (2008) (0)
- Network analysis identifies regulators of lineage-specific phenotypes in Mycobacterium tuberculosis (2020) (0)
- Faculty Opinions recommendation of Second-order selection for evolvability in a large Escherichia coli population. (2011) (0)
- A Quantitative, Genome-Wide Study of Translation Efficiency in E. coli (2018) (0)
- Quantitative proteomics signature profiling based on network contextualization (2015) (0)
- Artificial intelligence defines protein-based classification of thyroid nodules (2022) (0)
- Proteotypic peptides in the spotlight (0)
- QUANTITATIVE PROTEOMICS AND SYSTEMS BIOLOGY (2007) (0)
- Exploring the tertiary structure of apoE isoforms and their dynamic interaction with the amyloid beta peptide using cross-linking mass spectrometry and bioinformatics (2018) (0)
- Puedo confiar en mis experimentos de SRM (2012) (0)
- Mobi-DIK (Ion Mobility DIA Analysis Kit): Targeted analysis software for diaPASEF data improves proteome coverage (2019) (0)
- Ultra-sensitive proteome profiling of FACS-isolated cell populations by data-independent acquisition-MS: Application to human hematopoietic stem and progenitor cells (2018) (0)
- The mouse metallomic landscape of aging and metabolism (2022) (0)
- Recent advances of data‐independent acquisition mass spectrometry‐based proteomics (2023) (0)
- Quantitative Proteomic Analysis of Interferon Response in Human Liver Cells Using the Isotope Coded Affinity Tag Method and Novel Bioinformatics Tools Isotope of Phosphopeptides for Multiparallel Kinase Target Analysis and Identification of Phosphorylation Sites (2003) (0)
- Human TRiC in ATP/AlFx closed state (2021) (0)
- Amino-Terminal Protein Sequence Analysis (1994) (0)
- Applications of Stable Isotope Tagging Based Quantitative Proteomics in Cancer Research (2008) (0)
- Discovery and Multi-center Verification of Prostate Cancer Protein Biomarkers using Single-shot Short Gradient Microflow SWATH and MRMHR Mass Spectrometry (2019) (0)
- Systematic dissection of phosphorylation-dependent YAP1 complex formation elucidates a key role for PTPN14 in Hippo signal integration (2022) (0)
- ApoE N- and C-terminal domains are involved in amyloid beta binding: Insights from cross-linking mass spectrometry (2017) (0)
- Breast cancer classification based on proteotypes obtained by SWATH-MS (2017) (0)
- Enzyme expression kinetics by Escherichia coli during transition from rich to minimal media depends on proteome reserves (2023) (0)
- Advances of LC-MS and CZE-MS in proteome analysis (2006) (0)
- Epitope Tagging of Endogenous Proteins in Human Cells for Discovery of Novel Protein/Protein Interactions Quantitative Analysis of the Phosphoproteome of Resting and Activated Human Primary T Cells (2009) (0)
- Mapping specificity, entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen (2020) (0)
- Abstract A20: The DNA damage-induced phosphoproteome is modulated by inhibition of the MET receptor (2017) (0)
- Probing Adsorption / Desorption Processes at the Liquid / Solid Interface: Thiols and Proteins (2001) (0)
- ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma. (2023) (0)
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Other Resources About Ruedi Aebersold
What Schools Are Affiliated With Ruedi Aebersold?
Ruedi Aebersold is affiliated with the following schools:
- University of Zurich
- University of Alabama
- Simon Fraser University
- University of Oxford
- California Institute of Technology
- ETH Zurich
- University of British Columbia
- University of Melbourne
- University of Southern California
- Rockefeller University
- University of Manitoba
- University of Basel
- University of Washington
