Rupert Pearse

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Rupert Pearse

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Philosophy

Why Is Rupert Pearse Influential?

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According to Wikipedia, Rupert Pearse is a British physician specialising in intensive care medicine, and NIHR Professor of Intensive Care Medicine at Queen Mary University of London. Pearse graduated from St George's, University of London, in 1996.

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Rupert Pearse's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial (2021) (1083)
Mortality after surgery in Europe: a 7 day cohort study (2012) (1055)
Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. (2012) (730)
Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. (2014) (701)
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes (2014) (669)
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes (2014) (669)
Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445] (2005) (639)
Identification and characterisation of the high-risk surgical population in the United Kingdom (2006) (582)
Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery (2017) (499)
Functional definition and characterization of acute traumatic coagulopathy (2011) (472)
Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative Clinical Outcome (EPCO) definitions A statement from the ESA-ESICM joint taskforce on perioperative outcome measures (2015) (465)
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries (2016) (357)
Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study (2018) (334)
Meta‐analysis of the association between preoperative anaemia and mortality after surgery (2015) (323)
Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients. (2014) (305)
Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study (2018) (235)
Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients (2013) (227)
Changes in central venous saturation after major surgery, and association with outcome (2005) (225)
Mortality and utilisation of critical care resources amongst high‐risk surgical patients in a large NHS trust * (2008) (223)
The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock* (2009) (220)
Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications (2009) (185)
Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial (2010) (179)
Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection (2010) (176)
Incidence and associations of acute kidney injury after major abdominal surgery (2016) (167)
Perioperative cardiovascular monitoring of high-risk patients: a consensus of 12 (2015) (162)
Incidence of postoperative death and acute kidney injury associated with i.v. 6% hydroxyethyl starch use: systematic review and meta-analysis. (2014) (158)
A systematic review and consensus definitions for standardised end‐points in perioperative medicine: pulmonary complications (2018) (157)
Use of inotropes and vasopressor agents in critically ill patients (2012) (143)
Managing perioperative risk in patients undergoing elective non-cardiac surgery (2011) (139)
Age of patients undergoing surgery (2019) (136)
A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study (2017) (133)
Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2. (2011) (132)
Frequency of surgical treatment and related hospital procedures in the UK: a national ecological study using hospital episode statistics (2017) (131)
Serum creatinine changes associated with critical illness and detection of persistent renal dysfunction after AKI. (2014) (123)
International Study on Microcirculatory Shock Occurrence in Acutely Ill Patients* (2015) (120)
A national early warning score for acutely ill patients (2012) (119)
Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy (2017) (116)
Equipment review: An appraisal of the LiDCO™plus method of measuring cardiac output (2004) (116)
Association between complications and death within 30 days after noncardiac surgery (2019) (115)
Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study. (2016) (114)
Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. (2019) (114)
Mortality of emergency general surgical patients and associations with hospital structures and processes. (2016) (112)
Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial. (2015) (112)
EARLY MICROVASCULAR CHANGES IN SEPSIS AND SEVERE SEPSIS (2010) (111)
Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial (2019) (111)
Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial (2019) (111)
Perioperative medicine: the future of anaesthesia? (2012) (107)
Role of Central and Mixed Venous Oxygen Saturation Measurement in Perioperative Care (2009) (107)
Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries (2017) (105)
Restrictive Versus Liberal Transfusion Strategies for Older Mechanically Ventilated Critically Ill Patients: A Randomized Pilot Trial* (2013) (104)
36th International Symposium on Intensive Care and Emergency Medicine (2016) (103)
Summary of the British Consensus Guidelines on Intravenous Fluid Therapy for Adult Surgical Patients (GIFTASUP) – For Comment (2009) (96)
Current use of vasopressors in septic shock (2019) (90)
Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study (2020) (89)
High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study. (2011) (88)
Cardiac output monitoring: basic science and clinical application (2008) (87)
Improving detection of patient deterioration in the general hospital ward environment (2018) (86)
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta‐analysis (2018) (84)
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta‐analysis (2018) (84)
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis (2022) (80)
Acute kidney injury and mortality 1 year after major non‐cardiac surgery (2017) (77)
The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study (2018) (74)
Elevated urea-to-creatinine ratio provides a biochemical signature of muscle catabolism and persistent critical illness after major trauma (2019) (71)
Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial) (2018) (70)
Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non‐cardiac surgery (2019) (65)
Ergocalciferol and Microcirculatory Function in Chronic Kidney Disease and Concomitant Vitamin D Deficiency: An Exploratory, Double Blind, Randomised Controlled Trial (2014) (64)
Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study (2016) (64)
Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways (2016) (62)
Effect of dopexamine infusion on mortality following major surgery: Individual patient data meta-regression analysis of published clinical trials (2008) (61)
Intensive care utilization and outcomes after high-risk surgery in Scotland: a population-based cohort study (2017) (59)
Comparison of the prognostic accuracy of scoring systems, cardiopulmonary exercise testing, and plasma biomarkers: a single-centre observational pilot study. (2014) (58)
Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy. (2017) (56)
Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study. (2019) (56)
Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery (2017) (54)
A systematic review of the role of cardiopulmonary exercise testing in vascular surgery. (2012) (52)
Dynamic preload markers to predict fluid responsiveness during and after major gastrointestinal surgery: an observational substudy of the OPTIMISE trial. (2015) (50)
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative (2021) (49)
Pre-operative fasting and administration of regular medications in adult patients presenting for elective surgery. Has the new evidence changed practice? (1999) (49)
Prognostic studies of perioperative risk: robust methodology is needed. (2010) (49)
Protocolized fluid therapy in brain-dead donors: the multicenter randomized MOnIToR trial (2015) (48)
Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery (2016) (46)
Variation in global uptake of the Surgical Safety Checklist (2020) (43)
Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low‐, middle‐, and high‐income countries (2018) (43)
Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery (2017) (43)
Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. (2015) (42)
Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients (2004) (40)
Perioperative myocardial injury in patients receiving cardiac output-guided haemodynamic therapy: a substudy of the OPTIMISE Trial. (2015) (40)
Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery (2019) (40)
Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis. (2018) (39)
Does major surgery induce immune suppression and increase the risk of postoperative infection? (2016) (37)
Perioperative fluid therapy (2012) (37)
Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study (2014) (37)
Variation in haemodynamic monitoring for major surgery in European nations: secondary analysis of the EuSOS dataset (2015) (36)
Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients (2017) (35)
Preoperative abnormalities in serum sodium concentrations are associated with higher in-hospital mortality in patients undergoing major surgery. (2016) (35)
Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model (2018) (35)
Point prevalence of surgical checklist use in Europe: relationship with hospital mortality. (2015) (35)
Regional variation in critical care provision and outcome after high-risk surgery (2015) (34)
Using the 6‐minute walk test to predict disability‐free survival after major surgery (2019) (34)
Preoperative renal dysfunction and mortality after non‐cardiac surgery (2016) (34)
Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastr (2019) (34)
Surgical activity in England and Wales during the COVID-19 pandemic: a nationwide observational cohort study (2021) (33)
Clinical review: How to optimize management of high-risk surgical patients (2004) (30)
Resource requirements for reintroducing elective surgery during the COVID-19 pandemic: modelling study (2020) (30)
Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis (2017) (29)
ICU admission after surgery: who benefits? (2017) (28)
Prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure: a systematic review and meta-analysis (2021) (28)
Prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure: a systematic review and meta-analysis (2021) (28)
Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study (2015) (28)
Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis (2019) (28)
Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study (2019) (27)
Should we use central venous saturation to guide management in high-risk surgical patients? (2006) (25)
A systematic review and meta-analysis of return to work after mild Traumatic brain injury (2018) (25)
EuSOS: European surgical outcomes study. (2011) (24)
Depth of Anesthesia and Postoperative Delirium. (2019) (24)
Effect of day of the week on short‐ and long‐term mortality after emergency general surgery (2017) (23)
Current use of inotropes in circulatory shock (2021) (23)
Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study. (2020) (22)
Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT (2018) (22)
Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT (2018) (22)
Mixed and Central Venous Oxygen Saturation (2005) (22)
Intensive Care after High-risk Surgery: What's in a Name? (2016) (22)
Current research priorities in perioperative intensive care medicine (2017) (22)
Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial (2021) (21)
Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery (2015) (20)
Swedish surgical outcomes study (SweSOS): An observational study on 30-day and 1-year mortality after surgery (2016) (20)
The use of early intervention to prevent postoperative complications (2009) (20)
Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow (2013) (20)
Changes in gene expression following trauma are related to the age of transfused packed red blood cells (2015) (20)
American Society of Anesthesiologists Score: still useful after 60 years? Results of the EuSOS Study (2015) (20)
Extending the role of lactate measurement into the prehospital environment (2009) (19)
Mortality after surgery in Europe – Authors' reply (2013) (18)
Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients (2012) (18)
Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial. (2021) (18)
Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data (2019) (17)
Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies (2019) (17)
Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery (2018) (17)
Are we close to the ideal intravenous fluid? (2017) (17)
Mortality after surgery with SARS-CoV-2 infection in England: a population-wide epidemiological study (2021) (16)
Understanding decision making about major surgery: protocol for a qualitative study of shared decision making by high-risk patients and their clinical teams (2020) (16)
The Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial. Report of the protocol for a pragmatic randomized controlled trial of CPAP to prevent respiratory complications and improve survival following major abdominal surgery. (2017) (16)
Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study (2018) (16)
Perioperative haemodynamic therapy for major gastrointestinal surgery: the effect of a Bayesian approach to interpreting the findings of a randomised controlled trial (2019) (16)
Arterial pulse pressure and postoperative morbidity in high‐risk surgical patients (2018) (15)
Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE) (2022) (15)
Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow (2013) (15)
What are the optimum components in a care bundle aimed at reducing post-operative pulmonary complications in high-risk patients? (2018) (15)
Critical care admission of South African (SA) surgical patients: Results of the SA Surgical Outcomes Study. (2017) (15)
Non-invasive ventilation to avoid tracheal intubation in a patient with Guillain-Barré syndrome. (2003) (14)
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database (2020) (14)
Pre-specification of statistical analysis approaches in published clinical trial protocols was inadequate. (2018) (14)
Acute kidney injury in COVID-19: multicentre prospective analysis of registry data (2021) (14)
The incidence of myocardial injury following post-operative Goal Directed Therapy (2007) (14)
MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: prospective observational mechanistic cohort study. (2020) (13)
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research (2019) (13)
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research (2019) (13)
Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry (2008) (12)
Predictive Value of S100-B and Copeptin for Outcomes following Seizure: The BISTRO International Cohort Study (2015) (12)
Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma (2015) (12)
Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners (2018) (11)
An analysis of admission, discharge and bed occupancy of stroke patients aged 65 and over in English hospitals (1998) (11)
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study (2021) (11)
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study (2021) (11)
Perioperative fluid management: moving toward more answers than questions—a commentary on the RELIEF study (2019) (11)
Peri-operative troponin monitoring using a prototype high-sensitivity cardiac troponin I (hs-cTnI) assay: comparisons with hs-cTnT and contemporary cTnI assays (2014) (11)
Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine (2016) (10)
Do integrated care pathways have a place in critical care? (2012) (10)
Association Between Myocardial Injury and Cardiovascular Outcomes of Orthopaedic Surgery: A Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Substudy. (2020) (10)
Using oxygen delivery targets to optimize resuscitation in critically ill patients (2010) (10)
A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT (2019) (10)
The role of goal-directed therapy in the prevention of acute kidney injury after major gastrointestinal surgery: Substudy of the OPTIMISE trial. (2019) (9)
A restrictive versus liberal transfusion strategy to prevent myocardial injury in patients undergoing surgery for fractured neck of femur: a feasibility randomised trial (RESULT-NOF). (2020) (9)
Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice (2014) (9)
Socioeconomic deprivation and long-term outcomes after elective surgery: analysis of prospective data from two observational studies. (2020) (9)
Peri-operative hemodynamic therapy: only large clinical trials can resolve our uncertainty (2011) (9)
Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London (2021) (9)
Medical emergency teams: implementation and outcome measurement (2007) (8)
Preoperative Vitamin D Concentration and Cardiac, Renal, and Infectious Morbidity after Noncardiac Surgery. (2019) (8)
Resource requirements for reintroducing elective surgery in England during the COVID-19 pandemic: a modelling study (2020) (8)
Chronotropic incompetence and myocardial injury after noncardiac surgery: planned secondary analysis of a prospective observational international cohort study (2019) (8)
Pro-Con Debate: We should not Measure Cardiac output in Critical Care (2009) (8)
Is it the end of the road for synthetic starches in critical illness? (2013) (8)
Can we safely continue to offer surgical treatments during the COVID-19 pandemic? (2020) (8)
In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study. (2017) (7)
Ethnicity and acute hospital admissions: Multi-center analysis of routine hospital data (2021) (7)
Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study (2012) (7)
Understanding the performance of a pan-African intervention to reduce postoperative mortality: a mixed-methods process evaluation of the ASOS-2 trial. (2021) (7)
Functional decline after major elective non‐cardiac surgery: a multicentre prospective cohort study (2021) (7)
Intensive care admission and hospital mortality in the elderly after non-cardiac surgery. (2018) (7)
Prospective observational study of postoperative infection and outcomes after noncardiac surgery: analysis of prospective data from the VISION cohort. (2020) (7)
Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries (2022) (6)
Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery (2009) (6)
Short-term neurocognitive and symptomatic outcomes following mild traumatic brain injury: A prospective multi-centre observational cohort study (2017) (6)
Steroids to prevent postextubation laryngeal oedema (2007) (6)
Preoperative Anaemia Is Associated With Poor Clinical Outcome in Non-cardiac Surgery Patients (2015) (6)
Correction to: Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial) (2018) (6)
Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study. (2021) (6)
Pragmatic trials in peri‐operative medicine: why, when and how? (2018) (6)
Frequency of surgical treatment and related hospital procedures in the United Kingdom: A national ecological study using hospital episode statistics (2017) (6)
Catabolism in Critical Illness: A Reanalysis of the REducing Deaths due to OXidative Stress (REDOXS) Trial* (2022) (6)
The need for data describing the surgical population in Latin America. (2022) (6)
Saving money: An ideal driver for improved perioperative care? (2017) (5)
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study (2020) (5)
Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients (2014) (5)
Early goal directed therapy reduces morbidity and length of hospital stay following high-risk surgery (2005) (5)
Cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery. (2019) (5)
Correction: Improving care at scale: Process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial). [Implement Sci. (2018), 13 (142)] DOI: 10.1186/s13012-018-0823-9 (2018) (5)
Neither magic bullet nor a mere tool: negotiating multiple logics of the checklist in healthcare quality improvement. (2019) (5)
Another inconvenient truth: meeting the challenge of preventing poor surgical outcomes. (2010) (4)
Identification of myocardial injury using perioperative troponin surveillance in major noncardiac surgery and net benefit over the Revised Cardiac Risk Index (2021) (4)
Postoperative Outcomes Associated With Procedural Sedation Conducted by Physician and Nonphysician Anesthesia Providers: Findings From the Prospective, Observational African Surgical Outcomes Study (2021) (4)
Postoperative infection and mortality following elective surgery in the International Surgical Outcomes Study (ISOS). (2021) (4)
Routine postoperative noninvasive respiratory support and pneumonia after elective surgery: a systematic review and meta-analysis of randomised trials (2021) (4)
Pulse pressure and postoperative morbidity in high risk surgical patients. (2017) (4)
Haemodynamic monitoring and management of the circulation in intensive care (2004) (4)
Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia (2018) (4)
Association between use of enhanced recovery after surgery protocols and postoperative complications in colorectal surgery in Europe: The EuroPOWER international observational study. (2022) (4)
ASSOCIATION BETWEEN HIGH-SENSITIVITY TROPONIN I AND MAJOR CARDIOVASCULAR EVENTS AFTER NON-CARDIAC SURGERY (2020) (4)
The relationship between central venous saturation and outcome following high-risk surgery (2004) (4)
Peri-operative goal-directed therapy: A definitive answer remains elusive. (2018) (4)
Mortality after surgery in Ireland – Authors' reply (2013) (3)
Steroids for cardiac surgery: has the story finally ended? (2015) (3)
Novel methods to identify and measure catabolism (2021) (3)
Long-term mortality following complications after elective surgery: a secondary analysis of pooled data from two prospective cohort studies (2022) (3)
Evidence-based medicine: the clue is in the name. (2017) (3)
Development of a Clinical Prediction Model for In-hospital Mortality from the South African Cohort of the African Surgical Outcomes Study (2020) (3)
Enhanced peri‐operative care to improve outcomes for high‐risk surgical patients in Brazil: a single‐centre before‐and‐after cohort study (2022) (3)
REspiratory COmplications after abdomiNal surgery (RECON): study protocol for a multi-centre, observational, prospective, international audit of postoperative pulmonary complications after major abdominal surgery. (2020) (3)
Correction. Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicenter prospective cohort study of cardiopulmonary exercise testing prior to major noncardiac surgery. (2016) (3)
Learning from the EPOCH trial (Editorial) What we have learnt from a trial of an intervention to improve survival following emergency laparotomy? (2019) (3)
The African Surgical OutcomeS-2 (ASOS-2) Pilot Trial, a mixed-methods implementation study (2019) (3)
Cardiac troponins in sepsis: an indication for echocardiography?*. (2014) (3)
Mean systemic pressure monitoring (2014) (2)
Major gastrointestinal surgery is associated with a specific gene expression profile that is quantitatively associated with infectious complications: 1AP4-2 (2014) (2)
Perioperative haemodynamic therapy: Why are recommendations not being adopted? (2019) (2)
Abstracts of the Spring Anaesthetic Research Society Meeting (ARS) The Royal College of Anaesthetists, London, UK, April 21–22, 2015 (2015) (2)
Preprints in perioperative medicine: immediacy for the greater good. (2021) (2)
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts (2021) (2)
A rational approach to fluid and volume management (2014) (2)
Prevention of Respiratory Insufficiency after Surgical Management (PRISM) trial: report of the protocol for a pragmatic randomised controlled trial of Continuous Positive Airway Pressure (CPAP) to prevent respiratory complications and improve survival following major abdominal surgery. (2016) (2)
ESICM LIVES 2016: part one (2016) (2)
The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia (2020) (2)
Feasibility and diagnostic accuracy of Telephone Administration of an adapted wound heaLing QuestiONnaire for assessment for surgical site infection following abdominal surgery in low and middle-income countries (TALON): protocol for a study within a trial (SWAT) (2021) (2)
Estimated surgical requirements in England after COVID-19: a modelling study using hospital episode statistics (2020) (2)
Contemporary use of antimicrobial prophylaxis for surgical patients (2021) (2)
The association between ICU admission and emergency hospital readmission following emergency general surgery (2019) (2)
Decolonizing Global Surgery (2022) (2)
Should nutritional therapy be modified to account for mitochondrial dysfunction in critical illness? (2021) (2)
The whole truth and nothing but the truth: the need for full reporting of randomised trials (2015) (1)
Barriers to Quality Perioperative Care Delivery in Low- and Middle-Income Countries: A Qualitative Rapid Appraisal Study (2022) (1)
Trends in Hospital Admissions Associated with an Acute Kidney Injury in England 1998–2020: a Repeated Cross-Sectional Study (2021) (1)
Water, taken in moderation, cannot hurt anybody (Mark Twain 1835–1910) (2010) (1)
Perioperative plasma cortisol levels and myocardial injury after non-cardiac surgery (2019) (1)
Socioeconomic deprivation and surgical outcomes: ISOS and VISION-UK sub-study (Statistical Analysis Plan) (2020) (1)
The effects of preoperative moderate to severe anaemia on length of hospital stay: A propensity score-matched analysis in non-cardiac surgery patients. (2021) (1)
Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery (2023) (1)
Contemporary perioperative management of ACE‐inhibitors and angiotensin receptor blockers (2018) (1)
Perioperative haemodynamic therapy for major gastrointestinal surgery (2019) (1)
Inadequate pre‐operative evaluation and preparation 1 (2001) (1)
Serum microRNAs and perioperative myocardial injury (2019) (1)
Prevention of postoperative pulmonary complications in the hypoxaemic patient - gathering the evidence for noninvasive respiratory support. (2020) (1)
Perioperative Care Pathways in Low- and Lower-Middle-Income Countries: Systematic Review and Narrative Synthesis (2022) (1)
Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery (2023) (1)
Perioperative management of the high-risk surgical patient (2008) (1)
Anaesthesia research capacity: time for a rethink in light of the COVID‐19 pandemic (2020) (1)
Opportunities for shared decision-making about major surgery: findings from a multi-method qualitative study of decision-making about orthopaedic, colorectal and cardio thoracic surgery with high risk patients (2022) (1)
High-Sensitivity Cardiac Troponin I thresholds to identify myocardial injury after noncardiac surgery: a cohort study. (2023) (1)
Attitudes of multimorbid patients to surviving future acute illness and subsequent functional disability: A systematic review (2020) (1)
Change in healthcare utilisation after surgical treatment: observational study of routinely collected patient data from primary and secondary care (2022) (1)
Intensive care admission and hospital mortality in the elderly after non-cardiac surgery (2018) (1)
Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa (2021) (1)
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial (2023) (1)
Mandatory vaccination of National Health Service staff against COVID-19: more harm than good? (2022) (1)
The Barts Health NHS Trust COVID-19 cohort: characteristics, outcomes and risk scoring of patients in East London. (2021) (1)
Latin American surgical outcomes study: study protocol for a multicentre international observational cohort study of patient outcomes after surgery in Latin American countries (2022) (0)
Critical care clinical conundrums (2003) (0)
Adjusting meta-analysis data to reduce heterogeneity: the need for objective evaluation of observational studies. Response to Br J Anaesth 2022; 128: e303-5. (2022) (0)
Risk factors for acute organ failure in ICU patients with single organ (respiratory) dysfunction or failure: an international, prospective, cohort study (2012) (0)
Nutritional interventions improve QoL (2014) (0)
[Perioperative fluid therapy]. (2012) (0)
The limitations of shared decision-making in surgery. (2022) (0)
Association of preoperative heart rate with postoperative myocardial injury (2015) (0)
Clinical academics in the NHS: a cross-section study of research engagement during the monkeypox pandemic (2023) (0)
Opportunities for shared decision-making about major surgery with high-risk patients: a multi-method qualitative study. (2023) (0)
Association of Preoperative Growth Differentiation Factor-15 Concentrations and Postoperative Cardiovascular Events after Major Noncardiac Surgery (2023) (0)
The impact of REstrictive versUs Liberal Transfusion strategy on cardiac Injury in patients undergoing surgery for fractured Neck Of Femur: a feasibility randomised controlled trial (RESULT-NOF) (2020) (0)
Doing nothing is simply not an option: why framing of choices matters in surgical shared decision-making (2022) (0)
Assessing and preparing patients with medical conditions for major surgery (2020) (0)
Postoperative CPAP after major abdominal surgery - Authors' reply. (2022) (0)
Iron overdose (1991) (0)
Sugammadex to prevent postoperative pulmonary complications: a practice survey (2020) (0)
Postoperative outcomes associated with surgical care for women in Africa: an international risk-adjusted analysis of prospective observational cohorts (2022) (0)
Non-invasive and continuous arterial pressure monitoring (2014) (0)
Patient outcome following major surgery (2014) (0)
Mediterranean Fever (1895) (0)
Post-surgery mortality in Poland – Author's reply (2019) (0)
DeVita MA, Hillman K, Bellomo R (Eds): Medical Emergency Teams: Implementation and Outcome Measurement,1st edition. New York: Springer (2006) (0)
Determining the Minimum Dataset for Surgical Patients in Africa: A Delphi Study (2022) (0)
Association between preoperative resting heart rate and postoperative myocardial injury in patients undergoing non-cardiac surgery (2015) (0)
Perioperative Hemodynamic Monitoring and Goal Directed Therapy: ScvO2 monitoring (2014) (0)
Round table discussion: How do I manage acute on chronic liver failure in my ICU? (2014) (0)
Letter in Response to 'Classification of Traumatic Brain Injury Severity Using Informed Data Reduction in a Series of Binary Classifier Algorithms'. (2016) (0)
Intraoperative Driving Pressure and Postoperative Pulmonary Complications After Abdominal Surgery – A Posthoc Propensity Score–Weighted Cohort Analysis of the LAS VEGAS Study Comparing Open to Closed Surgery (2020) (0)
Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies (2019) (0)
' s response to reviews The incidence of myocardial injury following post-operative (2007) (0)
Functional capacity and preoperative risk evaluation – Authors' reply (2019) (0)
Commentary Should we use central venous saturation to guide management in high-risk surgical patients? (2006) (0)
Liberal or restrictive antimicrobial prophylaxis for surgical site infection: systematic review and meta-analysis of randomised trials. (2022) (0)
Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis (2023) (0)
Alternative Substrates in the Critically Ill Subject (ASICS): Safety, Feasibility, Tolerability and Metabolic Profiling of a Novel Ketogenic Feed (2023) (0)
Preoperative systemic inflammation and myocardial injury in non-cardiac surgery (2018) (0)
Commentary Extending the role of lactate measurement into the prehospital (2009) (0)
Faculty Opinions recommendation of Systematic review of the literature for the use of oesophageal Doppler monitor for fluid replacement in major abdominal surgery. (2008) (0)
Perioperative Haemodynamic Optimisation (2019) (0)
Extravascular Lung Water Measurement (2007) (0)
Liberal Versus Restrictive Antimicrobial Prophylaxis for Surgical Site Infection: Systematic Review and Meta-Analysis of Randomised Trials (2020) (0)
The Value of Albert's Test and Line Bisection in Geriatric Patients (1998) (0)
Members of the EPOCH trial group (2019) (0)
Letter in response to 'Classification algorithms for the identification of structural injury in TBI using brain electrical activity' (2015) (0)
Reply letter to: "A Commentary on "Cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery, Health Economic Evaluation" (Int J Surg 2019; Epub ahead of print)". (2019) (0)
Health Resource Utilisation and Disparities: an Ecological Study of Admission Patterns Across Ethnicity in England Between 2017 and 2020 (2022) (0)
Additional file 1: of Variation in haemodynamic monitoring for major surgery in European nations: secondary analysis of the EuSOS dataset (2015) (0)
Association between Cardiac Index and Mortality in Patients Assessed on the Ward by a Nurse-Led Critical Care Outreach Team (2008) (0)
Vasopressors and inotropes (2014) (0)
Pioglitazone for optimisation of clinical nutrition therapy in the critically ill patient: A Systematic Review (2022) (0)
Initiation of nutrition in the intensive care unit and the reasons for its delay: a prospective audit (2008) (0)
Emergency hospital admissions associated with non-communicable diseases 1998-2018 in England, Wales and Scotland: an ecological study. (2021) (0)
High-sensitivity Troponin I Predicts Major Cardiovascular Events after Non-Cardiac Surgery: A Vascular Events in Non-Cardiac Surgery Patients Cohort Evaluation (VISION) Substudy. (2023) (0)
A transcriptomic approach to understand patient susceptibility to pneumonia after abdominal surgery (2023) (0)
Perioperative blood transfusion is associated with a characteristic immune response, excess infectious complications and death in patients undergoing scheduled major gastrointestinal surgery: 6AP2-1 (2014) (0)
Anaesthesia providers and maternal mortality in Africa - Authors' reply. (2019) (0)
Abstracts of the Winter Anaesthetic Research Society Meeting (ARS) The Royal College of Anaesthetists, London, UK, October 1–2, 2013 (2014) (0)
Individualised targeted haemodynamic therapy in high-risk surgical patients - authors' reply. (2015) (0)
Oral Sessions_Wednesday_14 October 2009 (2009) (0)
Short and long term outcome, critical care usage and predictors of mortality following emergency laparotomy in Scotland (2016) (0)
Cost Savings from Perioperative Goal-directed Therapy (2021) (0)
Long-term healthcare use after postoperative complications: a prospective analysis of linked primary and secondary care routine data (2023) (0)
Cost Savings from Perioperative Goal-directed Therapy Researchers (2019) (0)
Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial: A pragmatic randomised controlled trial of continuous positive airway pressure (CPAP) to prevent respiratory complications and improve survival following major abdominal surgery (2015) (0)
Where audit meets science: role of reporting and recommendations guidelines in service evaluations (2018) (0)
Can Pioglitazone be used for optimisation of clinical nutrition therapy in the critically ill patient?: A Systematic Review. (2023) (0)
A185 Infrared thermal imaging of the hand during vascular occlusion in healthy volunteers (2016) (0)
Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure. (2023) (0)
Bladder Tumours1Presented before the North Central Branch of the American Urological Association, Cleveland, Ohio, November 8–10, 1935.: Some Results, Favourable and Unfavourable (1935) (0)
Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure. (2023) (0)
Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model (2018) (0)
Post-operative intensive care: is it really necessary? (2019) (0)
Post-operative haemodynamic management of the general surgical patient. (2006) (0)
Use of hemodynamic algorithm after gastrointestinal surgery--reply. (2014) (0)
microRNA signatures of perioperative myocardial injury after elective non-cardiac surgery: prospective observational cohort study (2020) (0)
Towards a coordinated national strategy to improve survival after emergency laparotomy. (2019) (0)
Authors’ reply to Petros and colleagues (2011) (0)
Alternative Substrates in the Critically Ill Subject (ASICS): Safety, Feasibility, Tolerability and Metabolic Profiling of a Novel Ketogenic Feed (2023) (0)
Global Incidence and Associations of Acute Kidney Injury in the International Surgical Outcomes Study (ISOS) (2017) (0)
19 Short Term Recurrence and Severe Outcome Following Emergency Department Visit for Seizure: Results from the BISTRO International Prospective Trial (2014) (0)
The need for a joint response. Perioperative mortality in Latin America and the time for LASOS Study (2022) (0)
Acute respiratory distress syndrome (ARDS) (2004) (0)

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Other Resources About Rupert Pearse

en.wikipedia.org
www.qmul.ac.uk

What Schools Are Affiliated With Rupert Pearse?

Rupert Pearse is affiliated with the following schools:

Queen Mary University of London