Russ Altman
American biomedical scientist and academic
Russ Altman's AcademicInfluence.com Rankings
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Computer Science
Russ Altman's Degrees
- Doctorate Medicine Stanford University
- PhD Medical Information Sciences Stanford University
Why Is Russ Altman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Russ Biagio Altman is an American professor of bioengineering, genetics, medicine, and biomedical data science and past chairman of the bioengineering department at Stanford University. Education Altman holds an A.B. from Harvard College in 1983, a Ph.D. in medical information sciences from Stanford in 1989 and M.D. from Stanford Medical School in 1990. After his internship at Stanford, he became board certified in 1991 in internal medicine and in clinical informatics in 2014. After a year of post-doctoral research, he joined the faculty as assistant professor in 1992. He became full professor in 2004, and was chair of the department of bioengineering from 2007 to June 2012. He currently is the Kenneth Fong Professor of Engineering at Stanford, and an advisor to the Chan Zuckerberg Biohub. As of 2018, Altman was a founding co-editor of the Annual Review of Biomedical Data Science.
Russ Altman's Published Works
Published Works
- Missing value estimation methods for DNA microarrays (2001) (3484)
- Estimation of the warfarin dose with clinical and pharmacogenetic data. (2009) (1522)
- Diversity of gene expression in adenocarcinoma of the lung (2001) (1320)
- Guidelines for investigating causality of sequence variants in human disease (2014) (1160)
- Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes (2012) (1128)
- Doxorubicin pathways: pharmacodynamics and adverse effects (2011) (1073)
- The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes (2008) (975)
- On the Opportunities and Risks of Foundation Models (2021) (938)
- Principal components analysis to summarize microarray experiments: application to sporulation time series. (1999) (854)
- Clinical assessment incorporating a personal genome (2010) (692)
- Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features (2016) (653)
- A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae) (2003) (597)
- Data-Driven Prediction of Drug Effects and Interactions (2012) (591)
- Machine learning in chemoinformatics and drug discovery. (2018) (509)
- Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity (2016) (502)
- PharmGKB: the Pharmacogenetics Knowledge Base (2002) (397)
- Integrating genotype and phenotype information: an overview of the PharmGKB project (2001) (383)
- Metformin pathways: pharmacokinetics and pharmacodynamics (2012) (365)
- Clinical interpretation and implications of whole-genome sequencing. (2014) (365)
- Cloud-based simulations on Google Exacycle reveal ligand-modulation of GPCR activation pathways (2013) (358)
- Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). (2011) (351)
- Nonparametric methods for identifying differentially expressed genes in microarray data (2002) (338)
- Genomic Research and Human Subject Privacy (2004) (329)
- Investigating hypoxic tumor physiology through gene expression patterns (2003) (319)
- SAFA: semi-automated footprinting analysis software for high-throughput quantification of nucleic acid footprinting experiments. (2005) (316)
- The incidentalome: a threat to genomic medicine. (2006) (304)
- Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters. (2009) (301)
- Bioinformatics challenges for personalized medicine (2011) (259)
- Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery. (2004) (242)
- PharmGKB: the Pharmacogenomics Knowledge Base. (2013) (237)
- Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study (2013) (232)
- Research Paper: Creating an Online Dictionary of Abbreviations from MEDLINE (2002) (232)
- Challenges in the clinical application of whole-genome sequencing (2010) (231)
- Valproic acid pathway: pharmacokinetics and pharmacodynamics (2013) (230)
- WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation (2013) (225)
- Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature. (2002) (217)
- Web-scale pharmacovigilance: listening to signals from the crowd (2013) (211)
- Collective judgment predicts disease-associated single nucleotide variants (2013) (190)
- PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses (2015) (186)
- Cytochrome P450 2C9-CYP2C9. (2010) (186)
- From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource. (2011) (184)
- PharmGKB summary: cyclosporine and tacrolimus pathways (2013) (180)
- A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports (2012) (177)
- CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations (2013) (176)
- PharmGKB: A worldwide resource for pharmacogenomic information (2018) (169)
- Eukaryotic regulatory element conservation analysis and identification using comparative genomics. (2004) (168)
- Whole-genome expression analysis: challenges beyond clustering. (2001) (167)
- Graph Convolutional Neural Networks for Predicting Drug-Target Interactions (2018) (166)
- Predicting HLA class II antigen presentation through integrated deep learning (2019) (163)
- Pharmacogenomics: Challenges and Opportunities (2006) (162)
- Modelling biological processes using workflow and Petri Net models (2002) (161)
- Clopidogrel pathway. (2010) (153)
- Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence (2011) (149)
- Basic microarray analysis: grouping and feature reduction. (2001) (146)
- Research Paper: Using Petri Net Tools to Study Properties and Dynamics of Biological Systems (2004) (146)
- PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19 (2012) (140)
- PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8 (2012) (133)
- Informatics confronts drug-drug interactions. (2013) (130)
- PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base (2004) (130)
- Reconstruction of the Mouse Otocyst and Early Neuroblast Lineage at Single-Cell Resolution (2014) (129)
- Discovery and Explanation of Drug-Drug Interactions via Text Mining (2011) (128)
- Pharmspresso: a text mining tool for extraction of pharmacogenomic concepts and relationships from full text (2009) (127)
- Finding haplotype tagging SNPs by use of principal components analysis. (2004) (126)
- Characterizing the microenvironment surrounding protein sites (1995) (126)
- Cytochrome P450 2D6. (2009) (124)
- Using text to build semantic networks for pharmacogenomics (2010) (123)
- Celecoxib pathways: pharmacokinetics and pharmacodynamics. (2012) (122)
- PharmGKB summary: very important pharmacogene information for CYP3A5. (2012) (121)
- Health-information altruists--a potentially critical resource. (2005) (119)
- Pharmacogenomics and bioinformatics: PharmGKB. (2010) (118)
- PharmGKB: a logical home for knowledge relating genotype to drug response phenotype (2007) (117)
- PharmGKB summary: methotrexate pathway. (2011) (117)
- Challenges for biomedical informatics and pharmacogenomics. (2002) (115)
- RNAML: a standard syntax for exchanging RNA information. (2002) (112)
- The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge (2007) (112)
- The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response (2015) (111)
- GAPSCORE: finding gene and protein names one word at a time (2004) (111)
- Improving the prediction of disease-related variants using protein three-dimensional structure (2011) (110)
- Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO) (2003) (110)
- Text mining for biology - the way forward: opinions from leading scientists (2008) (109)
- Average core structures and variability measures for protein families: application to the immunoglobulins. (1995) (107)
- Independent component analysis: Mining microarray data for fundamental human gene expression modules (2010) (105)
- Codeine and morphine pathway. (2009) (104)
- High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis (2008) (103)
- Emerging scientific applications in data mining (2002) (100)
- PharmGKB summary: ibuprofen pathways (2015) (99)
- A curriculum for bioinformatics: the time is ripe (1998) (99)
- Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism. (2010) (98)
- Robust recognition of zinc binding sites in proteins (2007) (98)
- RiboWeb: An Ontology-Based System for Collaborative Molecular Biology (1999) (98)
- Potential T-cell and B-cell Epitopes of 2019-nCoV (2020) (96)
- 3D deep convolutional neural networks for amino acid environment similarity analysis (2017) (95)
- PharmGKB: Understanding the Effects of Individual Genetic Variants (2008) (94)
- VKORC1 pharmacogenomics summary. (2010) (93)
- PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. (2014) (91)
- Geographic Distribution of US Cohorts Used to Train Deep Learning Algorithms. (2020) (91)
- PharmGKB summary: tamoxifen pathway, pharmacokinetics (2013) (90)
- PharmGKB summary: very important pharmacogene information for UGT1A1 (2014) (89)
- Using text analysis to identify functionally coherent gene groups. (2002) (89)
- PharmGKB summary: fluoropyrimidine pathways. (2010) (89)
- WebFEATURE: an interactive web tool for identifying and visualizing functional sites on macromolecular structures (2003) (88)
- Very important pharmacogene summary ADRB2 (2010) (88)
- Time to Organize the Bioinformatics Resourceome (2005) (87)
- Platelet aggregation pathway. (2011) (87)
- Large-scale extraction of gene interactions from full-text literature using DeepDive (2015) (87)
- Choosing SNPs using feature selection (2005) (86)
- Structural inference of native and partially folded RNA by high-throughput contact mapping (2008) (85)
- PharmGKB summary: caffeine pathway (2012) (84)
- PharmGKB summary: very important pharmacogene information for CYP1A2 (2012) (84)
- The ethics of characterizing difference: guiding principles on using racial categories in human genetics (2008) (83)
- Recent progress in automatically extracting information from the pharmacogenomic literature. (2010) (83)
- Sequence-specific 1H NMR assignments and secondary structure in solution of Escherichia coli trp repressor. (1990) (83)
- Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma. (2017) (82)
- Protein sequence design with a learned potential (2020) (82)
- Turning limited experimental information into 3D models of RNA. (2010) (81)
- A global network of biomedical relationships derived from text (2018) (79)
- PROTEAN: Deriving Protein Structure from Constraints (1986) (78)
- The RNA Ontology Consortium: an open invitation to the RNA community. (2006) (78)
- Semiautomated and rapid quantification of nucleic acid footprinting and structure mapping experiments (2008) (77)
- Extending and evaluating a warfarin dosing algorithm that includes CYP4F2 and pooled rare variants of CYP2C9 (2010) (76)
- MScanner: a classifier for retrieving Medline citations (2008) (75)
- Thiopurine pathway. (2010) (74)
- Genetics. Genomic research and human subject privacy. (2004) (74)
- MARS: discovering novel cell types across heterogeneous single-cell experiments (2020) (73)
- A method for inferring medical diagnoses from patient similarities (2013) (73)
- Decaying relevance of clinical data towards future decisions in data-driven inpatient clinical order sets (2017) (73)
- Selective serotonin reuptake inhibitors pathway. (2009) (72)
- Examining the Use of Real‐World Evidence in the Regulatory Process (2019) (71)
- PharmGKB summary: tramadol pathway. (2014) (71)
- Predicting RNA Structure by Multiple Template Homology Modeling (2010) (70)
- A new disease-specific machine learning approach for the prediction of cancer-causing missense variants. (2011) (68)
- Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers. (2015) (68)
- White Paper: Training the Next Generation of Informaticians: The Impact of "BISTI" and Bioinformatics - A Report from the American College of Medical Informatics (2004) (67)
- Using binning to maintain confidentiality of medical data (2002) (66)
- Bioinformatics and variability in drug response: a protein structural perspective (2012) (66)
- The Simbios National Center: Systems Biology in Motion (2008) (66)
- A call for the creation of personalized medicine databases (2006) (65)
- PharmGKB summary: carbamazepine pathway (2011) (64)
- Predicting allosteric communication in myosin via a pathway of conserved residues. (2007) (63)
- Recognizing protein binding sites using statistical descriptions of their 3D environments. (1998) (63)
- The computational analysis of scientific literature to define and recognize gene expression clusters. (2003) (63)
- Automating Data Acquisition into Ontologies from Pharmacogenetics Relational Data Sources Using Declarative Object Definitions and XML (2001) (63)
- Pacific symposium on biocomputing 2006 (2005) (63)
- Extracting and characterizing gene-drug relationships from the literature. (2004) (62)
- Biomedical term mapping databases (2004) (60)
- Predicting drug side-effects by chemical systems biology (2009) (60)
- A literature-based method for assessing the functional coherence of a gene group (2003) (60)
- Fast Flexible Modeling of RNA Structure Using Internal Coordinates (2011) (60)
- Using Multiple Microenvironments to Find Similar Ligand-Binding Sites: Application to Kinase Inhibitor Binding (2011) (59)
- PharmGKB summary: very important pharmacogene information for CYP2B6 (2010) (59)
- Standardized biogeographic grouping system for annotating populations in pharmacogenetic research (2018) (59)
- Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records. (2013) (59)
- Human Germline CRISPR-Cas Modification: Toward a Regulatory Framework (2015) (59)
- PharmGKB summary: phenytoin pathway (2012) (58)
- Large scale study of protein domain distribution in the context of alternative splicing. (2003) (58)
- PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. (2005) (57)
- Distinct contribution of electrostatics, initial conformational ensemble, and macromolecular stability in RNA folding (2007) (57)
- Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans. (2014) (56)
- PharmGKB very important pharmacogene: SLCO1B1. (2010) (55)
- Environmental and State-Level Regulatory Factors Affect the Incidence of Autism and Intellectual Disability (2014) (55)
- Chapter 7: Pharmacogenomics (2012) (55)
- Including Biological Literature Improves Homology Search (2000) (54)
- The FEATURE framework for protein function annotation: modeling new functions, improving performance, and extending to novel applications (2008) (54)
- Pharmacogenetics at scale: An analysis of the UK Biobank (2020) (54)
- The solution structures of Escherichia coli trp repressor and trp aporepressor at an intermediate resolution. (1991) (54)
- PharmGKB summary: gemcitabine pathway (2014) (54)
- Predicting inpatient clinical order patterns with probabilistic topic models vs conventional order sets (2016) (54)
- A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare Diseases (2019) (54)
- Knowledge-based instantiation of full atomic detail into coarse-grain RNA 3D structural models (2009) (53)
- Genome Wide Analysis of Drug-Induced Torsades de Pointes: Lack of Common Variants with Large Effect Sizes (2013) (53)
- Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks (2020) (53)
- PharmGKB summary: mycophenolic acid pathway (2014) (53)
- PharmGKB summary: venlafaxine pathway (2014) (52)
- Efficient Algorithms to Explore Conformation Spaces of Flexible Protein Loops (2007) (52)
- Bioinformatics in support of molecular medicine (1998) (52)
- Achieving high-sensitivity for clinical applications using augmented exome sequencing (2015) (52)
- RIBOWEB: Linking Structural Computations to a Knowledge Base of Published Experimental Data (1997) (51)
- Databases in the area of pharmacogenetics (2011) (51)
- Application of Information Technology: A Statistical Approach to Scanning the Biomedical Literature for Pharmacogenetics Knowledge (2004) (51)
- Cooperative transcription factor associations discovered using regulatory variation (2011) (49)
- Improving the explainability of Random Forest classifier - user centered approach (2018) (49)
- Very important pharmacogene summary for VDR (2012) (49)
- A deep learning framework to predict binding preference of RNA constituents on protein surface (2019) (48)
- A systematic comparison of three structure determination methods from NMR data: Dependence upon quality and quantity of data (1992) (48)
- Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients. (2019) (47)
- PharmGKB summary: citalopram pharmacokinetics pathway (2011) (47)
- Neurotoxicity of generic anesthesia agents in infants and children: an orphan research question in search of a sponsor. (2015) (47)
- ATOM3D: Tasks On Molecules in Three Dimensions (2020) (46)
- Computational methods for defining the allowed conformational space of 16S rRNA based on chemical footprinting data. (1996) (46)
- Improving structure-based function prediction using molecular dynamics. (2009) (46)
- Viewpoint: The Interactions Between Clinical Informatics and Bioinformatics: A Case Study (2000) (45)
- Improving data and knowledge management to better integrate health care and research (2013) (45)
- Content-based microarray search using differential expression profiles (2010) (45)
- A research roadmap for next-generation sequencing informatics (2016) (45)
- OrderRex: clinical order decision support and outcome predictions by data-mining electronic medical records (2016) (44)
- MutDB: annotating human variation with functionally relevant data (2003) (43)
- Platinum pathway. (2009) (43)
- PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics (2017) (43)
- Local kinetic measures of macromolecular structure reveal partitioning among multiple parallel pathways from the earliest steps in the folding of a large RNA molecule. (2006) (43)
- Pathway analysis of genome-wide data improves warfarin dose prediction (2013) (43)
- PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single‐drug pharmacogenetics (2008) (42)
- Integration and publication of heterogeneous text-mined relationships on the Semantic Web (2011) (42)
- Very important pharmacogene summary: thiopurine S-methyltransferase. (2010) (41)
- Pharmacogenomics Clinical Annotation Tool (PharmCAT) (2019) (41)
- High precision protein functional site detection using 3D convolutional neural networks (2018) (40)
- Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs. (2015) (40)
- Bisphosphonates pathway. (2011) (39)
- MODELING BIOLOGICAL PROCESSES USING WORKFLOW AND PETRI NET MODELS (2001) (39)
- PharmGKB: An Integrated Resource of Pharmacogenomic Data and Knowledge (2008) (39)
- LPFC: An internet library of protein family core structures (1997) (39)
- Are predicted structures good enough to preserve functional sites? (1999) (38)
- Determining the Genomic Locations of Repetitive DNA Sequences with a Whole-Genome Microarray: IS6110 in Mycobacterium tuberculosis (2002) (38)
- Identifying Druggable Targets by Protein Microenvironments Matching: Application to Transcription Factors (2014) (37)
- K-Means for Parallel Architectures Using All-Prefix-Sum Sorting and Updating Steps (2013) (37)
- PharmGKB summary: methylene blue pathway (2013) (37)
- Ontology Development for a Pharmacogenetics Knowledge Base (2001) (37)
- Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach (2015) (36)
- Microenvironment analysis and identification of magnesium binding sites in RNA. (2003) (36)
- Learning the Structure of Biomedical Relationships from Unstructured Text (2015) (36)
- Commentaries on “Informatics and Medicine: From Molecules to Populations” (2008) (36)
- Etoposide pathway. (2009) (36)
- PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6 (2012) (36)
- Ranking Adverse Drug Reactions With Crowdsourcing (2015) (36)
- Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges (2017) (36)
- Heuristic refinement method for determination of solution structure of proteins from nuclear magnetic resonance data. (1989) (36)
- PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics (2014) (36)
- A dynamic map for learning, communicating, navigating and improving therapeutic development (2017) (36)
- Homology modeling of TMPRSS2 yields candidate drugs that may inhibit entry of SARS-CoV-2 into human cells. (2020) (35)
- New strategies for the determination of macromolecular structure in solution. (1986) (35)
- Choosing Snps Using Feature Selection (2006) (35)
- Recognizing Complex, Asymmetric Functional Sites in Protein Structures Using a Bayesian Scoring Function (2003) (34)
- PharmGKB summary: very important pharmacogene information for G6PD (2012) (34)
- Drug Targets for Plasmodium falciparum: a post-genomic review/survey. (2006) (34)
- Tools for loading MEDLINE into a local relational database (2004) (34)
- The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response (2016) (33)
- Using ODIN for a PharmGKB revalidation experiment (2012) (33)
- PharmGKB summary: clozapine pathway, pharmacokinetics (2018) (32)
- Challenges for Intelligent Systems in Biology (2001) (32)
- Informatics in the care of patients: ten notable challenges. (1997) (32)
- Clustering protein environments for function prediction: finding PROSITE motifs in 3D (2007) (31)
- Using "big data" to dissect clinical heterogeneity. (2015) (31)
- Using the radial distributions of physical features to compare amino acid environments and align amino acid sequences. (1997) (31)
- Coherent Functional Modules Improve Transcription Factor Target Identification, Cooperativity Prediction, and Disease Association (2014) (31)
- Extracting Subject Demographic Information From Abstracts of Randomized Clinical Trial Reports (2007) (31)
- Knowledge-based Fragment Binding Prediction (2014) (30)
- CAMPAIGN: an open-source library of GPU-accelerated data clustering algorithms (2011) (30)
- Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants (2016) (30)
- PharmGKB summary: Efavirenz pathway, pharmacokinetics (2015) (30)
- Automated Construction of Structural Motifs for Predicting Functional Sites on Protein Structures (2002) (30)
- Atrial Fibrillation Burden Signature and Near-Term Prediction of Stroke: A Machine Learning Analysis. (2019) (29)
- Structural characterization of proteins using residue environments (2005) (29)
- Identification of promoter regions in the human genome by using a retroviral plasmid library-based functional reporter gene assay. (2003) (29)
- Modeling and Analyzing Biomedical Processes using Workflow/Petri Net Models and Tools (2004) (29)
- Reuse with PROTÉGÉ-II: from elevators to ribosomes (1995) (29)
- iTools: A Framework for Classification, Categorization and Integration of Computational Biology Resources (2008) (29)
- Editorial: Building successful biological databases (2004) (28)
- Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder (2018) (28)
- Sex-specific genetic effects across biomarkers (2019) (28)
- Mining biochemical information: lessons taught by the ribosome. (2002) (28)
- PharmGKB summary: isoniazid pathway, pharmacokinetics (2016) (28)
- AI in Medicine: The Spectrum of Challenges from Managed Care to Molecular Medicine (1999) (28)
- PharmGKB summary: sorafenib pathways (2017) (27)
- Heuristic refinement method for the derivation of protein solution structures: validation on cytochrome b562 (1988) (26)
- Interpretome: A Freely Available, Modular, and Secure Personal Genome Interpretation Engine (2011) (25)
- Computing disease incidence, prevalence and comorbidity from electronic medical records (2016) (25)
- Transfer learning enables prediction of CYP2D6 haplotype function (2020) (25)
- Prediction of calcium-binding sites by combining loop-modeling with machine learning (2009) (25)
- Constrained Global Optimization for Estimating Molecular Structure from Atomic Distances (2001) (25)
- PharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamics (2015) (25)
- Using a measure of structural variation to define a core for the globins (1995) (24)
- Reuse, CORBA, and knowledge-based systems (1998) (24)
- Opportunities and challenges for the computational interpretation of rare variation in clinically important genes (2021) (24)
- Pharmacogenomics: will the promise be fulfilled? (2011) (24)
- Missing Value Estimation (2003) (24)
- SLC19A1 pharmacogenomics summary (2010) (24)
- Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development (2017) (24)
- Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data (2015) (24)
- Finding an Average Core Structure: Application to the Globins (1994) (24)
- Development of an automated assessment tool for MedWatch reports in the FDA adverse event reporting system (2017) (23)
- Pharmacogenomics in Asian Subpopulations and Impacts on Commonly Prescribed Medications (2020) (23)
- RNA molecules with conserved catalytic cores but variable peripheries fold along unique energetically optimized pathways. (2011) (23)
- Vascular endothelial growth factor pathway. (2010) (23)
- PharmGKB summary: cytochrome P450, family 2, subfamily J, polypeptide 2: CYP2J2. (2011) (23)
- Automated Physician Order Recommendations and Outcome Predictions by Data-Mining Electronic Medical Records (2014) (23)
- The Pioglitazone Trek via Human PPAR Gamma: From Discovery to a Medicine at the FDA and Beyond (2018) (23)
- Constraint Satisfaction Techniques for Modeling Large Complexes: Application to the Central Domain of 16S Ribosomal RNA (1994) (23)
- Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site (2019) (23)
- PharmGKB summary: very important pharmacogene information for SLC22A1 (2014) (22)
- Probabilistic Structure Calculations: A Three-Dimensional tRNA Structure from Sequence Correlation Data (1993) (22)
- Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium (2020) (22)
- Combining Molecular Dynamics and Machine Learning to Improve Protein Function Recognition (2007) (22)
- Integrating systems biology sources illuminates drug action (2014) (22)
- A probabilistic pathway score (PROPS) for classification with applications to inflammatory bowel disease (2017) (22)
- Expanding a radiology lexicon using contextual patterns in radiology reports (2018) (22)
- Genome‐wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) (2017) (22)
- Indexing pharmacogenetic knowledge on the World Wide Web. (2003) (22)
- Representing genetic sequence data for pharmacogenomics: an evolutionary approach using ontological and relational models (2002) (22)
- Taxane pathway. (2009) (21)
- Towards a standard query model for sharing decision-support applications. (1994) (21)
- Data re-identification: societal safeguards. (2013) (21)
- Very important pharmacogene summary: sulfotransferase 1A1. (2009) (21)
- A New Era in Pharmacovigilance: Toward Real‐World Data and Digital Monitoring (2021) (21)
- Mice lacking the β2 adrenergic receptor have a unique genetic profile before and after focal brain ischaemia (2012) (20)
- Opportunities for developing therapies for rare genetic diseases: focus on gain-of-function and allostery (2017) (20)
- PharmGKB summary: very important pharmacogene information for CYP4F2 (2015) (20)
- Using imperfect secondary structure predictions to improve molecular structure computations (1999) (20)
- Coplanar and coaxial orientations of RNA bases and helices. (2007) (20)
- Classifying Non-Small Cell Lung Cancer Histopathology Types and Transcriptomic Subtypes using Convolutional Neural Networks (2019) (20)
- Data-driven human transcriptomic modules determined by independent component analysis (2018) (20)
- Pharmacogenomics and big genomic data: from lab to clinic and back again. (2018) (20)
- A functional analysis of disease-associated mutations in the androgen receptor gene. (2003) (19)
- Confidentiality in Genome Research (2006) (19)
- The dependence of a protein solution structure on the quality of the input NMR data. Application of the double-iterated Kalman filter technique to oxytocin (1990) (19)
- New feature: pathways and important genes from PharmGKB. (2009) (19)
- Towards a Cytokine-Cell Interaction Knowledgebase of the Adaptive Immune System (2008) (19)
- An integrative method for scoring candidate genes from association studies: application to warfarin dosing (2010) (19)
- Variations in the Binding Pocket of an Inhibitor of the Bacterial Division Protein FtsZ across Genotypes and Species (2015) (19)
- Introduction to Translational Bioinformatics Collection (2012) (19)
- Maternal–fetal and neonatal pharmacogenomics: a review of current literature (2010) (19)
- Sophia: Providing Basic Knowledge Services with a Common DBMS (1998) (19)
- RNA secondary structure as a reusable interface to biological information resources. (1997) (19)
- Ribosomal dynamics inferred from variations in experimental measurements. (2003) (18)
- The utility of general purpose versus specialty clinical databases for research: Warfarin dose estimation from extracted clinical variables (2010) (18)
- The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression (2019) (18)
- The Education Potential of the Pharmacogenetics and Pharmacogenomics Knowledge Base (PharmGKB) (2007) (18)
- Updating a bibliography using the related articles function within PubMed (1998) (18)
- Qualitative models of molecular function: linking genetic polymorphisms of tRNA to their functional sequelae (2002) (18)
- The SeqFEATURE library of 3D functional site models: comparison to existing methods and applications to protein function annotation (2008) (18)
- PharmGKB summary: voriconazole pathway, pharmacokinetics (2017) (18)
- Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals (2019) (18)
- PharmGKB summary: very important pharmacogene information for ABCG2 (2017) (18)
- Biomedical informatics training at Stanford in the 21st century (2007) (17)
- Building successful biological databases. (2004) (17)
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- Sophia: a flexible, Web-based knowledge server (1999) (17)
- PharmGKB summary: very important pharmacogene information for MT-RNR1 (2016) (17)
- Hierarchical Organization of Molecular Structure Computations (1998) (17)
- PharmGKB summary: dopamine receptor D2. (2011) (17)
- PharmGKB summary: very important pharmacogene information for PTGS2 (2011) (16)
- Remote thioredoxin recognition using evolutionary conservation and structural dynamics. (2011) (16)
- PharmGKB summary: very important pharmacogene information for human leukocyte antigen B (2015) (16)
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- Analyzing the vast coronavirus literature with CoronaCentral (2020) (15)
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- PharmGKB summary: very important pharmacogene information for the epidermal growth factor receptor (2013) (15)
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- Lamprey: tracking users on the World Wide Web. (1996) (14)
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- Clinical evaluation incorporating a personal genome (2010) (14)
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- PharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme (2010) (13)
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- PharmGKB summary: sertraline pathway, pharmacokinetics (2019) (12)
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- Population‐specific single‐nucleotide polymorphism confers increased risk of venous thromboembolism in African Americans (2016) (9)
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- A network paradigm predicts drug synergistic effects using downstream protein–protein interactions (2022) (0)
- Genetic information and molecular pathways recapitulate psychiatric drug prescriptions and diagnoses (2020) (0)
- Variation in the Binding Pocket of an Inhibitor of the Bacterial Division Protein FtsZ Across Genotypes, Nucleotide States, and Species (2014) (0)
- ATOM3D: Mutation Stability Prediction (MSP) Dataset (2021) (0)
- Opportunities and Challenges for Interpreting Rare Variation in Clinically Important Genes (2020) (0)
- Year : 2012 Using ODIN for a PharmGKB revalidation experiment (2017) (0)
- Using GPT-3 to Build a Lexicon of Drugs of Abuse Synonyms for Social Media Pharmacovigilance (2023) (0)
- Recommendations for achieving interoperable and shareable medical data in the USA (2022) (0)
- Editorial Board (1995) (0)
- Mapping transcriptional heterogeneity and metabolic networks in fatty livers at single-cell resolution (2022) (0)
- Can the Covid-19 Natural Experiment Teach Us About Care Value and System Preferences? (2021) (0)
- An Iron-Calcium-Miro Axis Influences Parkinson’s Risk and Neurodegeneration (2023) (0)
- From nut-2 to covid 19: What it teaches us?. the triple therapy for covid 19 (2020) (0)
- Achieving high-sensitivity for clinical applications using augmented exome sequencing (2015) (0)
- Investigating Ligand-Modulation of GPCR Activation Pathways (2014) (0)
- Systematic target function annotation of human transcription factors (2018) (0)
- Partial Compilation of Strategic Knowledge 1 (1999) (0)
- Gene set proximity analysis: expanding gene set enrichment analysis through learned geometric embeddings, with drug-repurposing applications in COVID-19 (2022) (0)
- Modeling Drug Combinatorial Effects in Inflammatory Bowel Disease (2018) (0)
- PhenClust, a standalone tool for identifying trends within sets of biological phenotypes using semantic similarity and the Unified Medical Language System metathesaurus (2021) (0)
- Using surface envelopes to constrain molecular modeling (2007) (0)
- Reuse with PROTÉGÉ -II: Adapting Problem-Solving Methods with Mapping Relations (1995) (0)
- Automated Diagnosis of Data-Model Conflicts (2016) (0)
- Association between spironolactone use and COVID-19 outcomes in population-scale claims data: a retrospective cohort study (2023) (0)
- Data-driven human transcriptomic modules determined by independent component analysis (2018) (0)
- ATOM3D: Residue Identity (RES) Dataset (2021) (0)
- Detecting Contradictory COVID-19 Drug Efficacy Claims from Biomedical Literature (2022) (0)
- Extracting chemical reactions from text using Snorkel (2020) (0)
- Genetic association studies using disease liabilities from deep neural networks (2023) (0)
- Biocomputing 2021: Proceedings of the Pacific Symposium, Kohala Coast, Hawaii, USA, January 3-7, 2021 (2020) (0)
- Plenary & keynote speakers (2016) (0)
- Probabilistic constraint network representation of biological structure (1994) (0)
- Characterizing the microenvironment surrounding protein sites data (1994) (0)
- Proceeding of the 3rd International Workshop on Data and Text Mining in Bioinformatics, DTMBIO 2009, Hong Kong, China, November 6, 2009 (2009) (0)
- FRONT MATTER (2019) (0)
- ATOM3D: Ligand Efficacy Prediction (LEP) Dataset (2021) (0)
- Comprehensive Assessment of Smoking and Sex Related Effects in Publicly Available Gene Expression Data (2021) (0)
- Faculty of 1000 evaluation for Toward a complete in silico, multi-layered embryonic stem cell regulatory network. (2012) (0)
- Ontological Issues in Pharmacogenomics (2007) (0)
- CL-01 Translation of Clinical Proteomics : Opportunities and Challenges (2013) (0)
- Biocomputing 2004, Proceedings of the Pacific Symposium, Hawaii, USA, 6-10 January 2004 (2004) (0)
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