Russel J. Reiter

Q: What Schools Are Affiliated With Russel J. Reiter

Russel J. Reiter is affiliated with the following schools: University of Innsbruck, University of Texas Health Science Center at San Antonio, University of Texas at San Antonio, University of Rochester

Russel J. Reiter's AcademicInfluence.com Rankings

Russel J. Reiter

Medical

#108

World Rank

#177

Historical Rank

#56

USA Rank

Pharmacology

World Rank

#10

Historical Rank

USA Rank

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Why Is Russel J. Reiter Influential?

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According to Wikipedia, Russel J. Reiter is an American researcher and Professor of Cell Systems and Anatomy at the University of Texas Health Science Center. He is one of the top highly cited researchers according to webometrics.

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Russel J. Reiter's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Pineal melatonin: cell biology of its synthesis and of its physiological interactions. (1991) (2174)
Regulation of antioxidant enzymes: a significant role for melatonin (2004) (1856)
One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species? (2007) (1459)
The pineal and its hormones in the control of reproduction in mammals. (1980) (1262)
Melatonin as an antioxidant: under promises but over delivers (2016) (1000)
Melatonin as a natural ally against oxidative stress: a physicochemical examination (2011) (993)
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. (2002) (987)
Actions of melatonin in the reduction of oxidative stress. A review. (2000) (952)
Oxidative damage in the central nervous system: protection by melatonin (1998) (895)
A review of the evidence supporting melatonin's role as an antioxidant (1995) (850)
Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography‐mass spectrometry (1995) (752)
The melatonin rhythm: both a clock and a calendar (1993) (745)
Extrapineal melatonin: sources, regulation, and potential functions (2014) (732)
Oxidative processes and antioxidative defense mechanisms in the aging brain 1 (1995) (727)
Melatonin: an ancient molecule that makes oxygen metabolically tolerable (2015) (713)
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK (2013) (687)
A review of the multiple actions of melatonin on the immune system (2005) (620)
Melatonin: The chemical expression of darkness (1991) (607)
Biochemical reactivity of melatonin with reactive oxygen and nitrogen species (2007) (592)
Melatonin stimulates brain glutathione peroxidase activity (1995) (591)
Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. (2003) (576)
Melatonin: a multitasking molecule. (2010) (554)
Melatonin membrane receptors in peripheral tissues: Distribution and functions (2012) (543)
Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate (2008) (540)
Significance of Melatonin in Antioxidative Defense System: Reactions and Products (2000) (538)
Pharmacological actions of melatonin in oxygen radical pathophysiology. (1997) (531)
A review of the molecular aspects of melatonin’s anti‐inflammatory actions: recent insights and new perspectives (2013) (530)
Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin (2003) (520)
Melatonin mitigates mitochondrial malfunction (2005) (517)
COVID-19: Melatonin as a potential adjuvant treatment (2020) (496)
Effects of Melatonin Treatment in Septic Newborns (2001) (496)
Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis (1993) (479)
Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin (2009) (471)
Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science. (2012) (469)
Melatonin-immune system relationships. (2002) (462)
Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations (2012) (459)
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines (2009) (453)
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance (2004) (451)
The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances (1993) (444)
Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. (2000) (439)
Melatonin and Its Relation to the Immune System and Inflammation (2000) (429)
Melatonin: reducing the toxicity and increasing the efficacy of drugs (2002) (428)
Melatonin: exceeding expectations. (2014) (426)
Melatonin, energy metabolism, and obesity: a review (2014) (424)
Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes (2013) (423)
Melatonin enhances plant growth and abiotic stress tolerance in soybean plants (2014) (420)
Melatonin, mitochondria, and cellular bioenergetics (2001) (413)
Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism (2015) (398)
Free Radical‐Mediated Molecular Damage (2001) (396)
Melatonin As a Free Radical Scavenger: Implications for Aging and Age‐Related Diseases a (1994) (385)
Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide (1997) (381)
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling (2012) (379)
Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of improved abiotic stress resistance in bermudagrass [Cynodon dactylon (L). Pers.] by exogenous melatonin (2014) (379)
Melatonin—A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitro a (1994) (370)
A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation. (1998) (368)
Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localization (1993) (366)
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review (2014) (365)
Melatonin and the ovary: physiological and pathophysiological implications. (2009) (364)
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease (2010) (362)
Melatonin and Reproduction Revisited (2009) (356)
Melatonin: from basic research to cancer treatment clinics. (2002) (355)
Melatonin and its metabolites: new findings regarding their production and their radical scavenging actions. (2007) (353)
Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation. (2000) (350)
Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. (1999) (344)
Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas (2017) (341)
Evaluation of the antioxidant activity of melatonin in vitro. (1996) (340)
Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence (1993) (337)
Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood. (2005) (334)
Cardiovascular diseases: protective effects of melatonin (2007) (329)
High levels of melatonin in the seeds of edible plants: possible function in germ tissue protection. (2000) (327)
Melatonin: clinical relevance. (2003) (322)
Melatonin and mitochondrial function. (2004) (321)
The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. (1993) (321)
Melatonin: Lowering the High Price of Free Radicals. (2000) (319)
Medical implications of melatonin: receptor-mediated and receptor-independent actions. (2007) (317)
Melatonin Synthesis and Function: Evolutionary History in Animals and Plants (2019) (317)
Actions of Melatonin in the Reduction of Oxidative Stress (2000) (314)
Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis (2017) (312)
Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis (2015) (309)
Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation (1997) (309)
Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart. (2003) (307)
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages (2005) (305)
Phytomelatonin: a review. (2009) (302)
Melatonin and cell death: differential actions on apoptosis in normal and cancer cells (2003) (299)
Melatonin as a radioprotective agent: a review. (2004) (299)
The mammalian pineal gland: structure and function. (1981) (298)
Melatonin: An Established Antioxidant Worthy of Use in Clinical Trials (2009) (298)
Oxidative stress of the newborn in the pre‐ and postnatal period and the clinical utility of melatonin (2009) (291)
The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness (2009) (290)
Causes of Oxidative Stress in the Pre- and Perinatal Period (2002) (289)
The pineal gland and melatonin in relation to aging: A summary of the theories and of the data (1995) (287)
Melatonin‐induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo (2000) (287)
Clinical uses of melatonin: evaluation of human trials. (2010) (287)
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin (1997) (287)
Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity (2011) (287)
The Safety of Melatonin in Humans (2016) (287)
Pharmacology and Physiology of Melatonin in the Reduction of Oxidative Stress in vivo (2000) (284)
Melatonin in relation to cellular antioxidative defense mechanisms. (1997) (284)
Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. (1995) (281)
The Oxidant/Antioxidant Network: Role of Melatonin (1999) (277)
Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. (1994) (275)
Phytomelatonin: Assisting Plants to Survive and Thrive (2015) (273)
Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications (1992) (272)
Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. (2009) (271)
Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress‐induced apoptosis of rat brain astrocytes (2004) (270)
N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant (2001) (268)
On the primary functions of melatonin in evolution: Mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals * (1995) (263)
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease (2000) (262)
Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin (2001) (260)
Pineal melatonin rhythm: reduction in aging Syrian hamsters. (1980) (259)
The ageing pineal gland and its physiological consequences (1992) (257)
Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin (2012) (255)
Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts (2016) (254)
Melatonin in plants. (2009) (254)
Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum. (1994) (253)
Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics (2016) (252)
Melatonin and pregnancy in the human. (2008) (252)
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction (2003) (248)
Melatonin protects against common deletion of mitochondrial DNA‐augmented mitochondrial oxidative stress and apoptosis (2007) (244)
High physiological levels of melatonin in the bile of mammals. (1999) (240)
The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives. (2013) (238)
Cancer metastasis: Mechanisms of inhibition by melatonin (2017) (237)
Melatonin: Current Status and Future Perspectives in Plant Science (2016) (237)
Antioxidant capacity of melatonin: A novel action not requiring a receptor (1993) (232)
Oxidative damage in the liver induced by ischemia-reperfusion: protection by melatonin. (1996) (232)
Detection and quantification of the antioxidant melatonin in Montmorency and Balaton tart cherries (Prunus cerasus). (2001) (231)
SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin (2015) (231)
Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high‐fat diet‐fed mice (2018) (230)
Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions (2018) (228)
The RNA‐seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation (2014) (227)
Age-associated reduction in nocturnal pineal melatonin levels in female rats. (1981) (227)
Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology. (2014) (222)
Melatonin and circadian biology in human cardiovascular disease (2010) (221)
Melatonin reduces nitric oxide synthase activity in rat hypothalamus (1996) (220)
Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. (2001) (220)
Basic mechanisms involved in the anti-cancer effects of melatonin. (2010) (216)
The modulatory role of melatonin on immune responsiveness. (2006) (215)
Melatonin-mitochondria interplay in health and disease. (2011) (215)
Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin (2002) (215)
Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin (2016) (214)
Melatonin is protective against MPTP-induced striatal and hippocampal lesions. (1996) (214)
Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks (1995) (211)
Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light (1998) (209)
Antioxidant actions of melatonin. (1997) (209)
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1‐dependent mechanism during ischemic‐stroke in mice (2015) (208)
Melatonin as an antioxidant: physiology versus pharmacology (2005) (207)
Reactive Oxygen Intermediates, Molecular Damage, and Aging: Relation to Melatonin (1998) (207)
Mechanisms of cancer inhibition by melatonin (2004) (205)
Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome (2000) (204)
Comparative physiology: pineal gland. (1973) (203)
Light at night, chronodisruption, melatonin suppression, and cancer risk: a review. (2007) (203)
Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy (2018) (203)
Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. (2004) (202)
Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrrioxamine (desferoxamine) in rat liver homogenates (2001) (202)
Obesity and metabolic syndrome: Association with chronodisruption, sleep deprivation, and melatonin suppression (2012) (202)
Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer (2010) (201)
The melatonin message: duration versus coincidence hypotheses. (1987) (199)
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical (2003) (197)
Characterization of high‐affinity melatonin binding sites in purified cell nuclei of rat liver (1994) (197)
Functional Pleiotropy of the Neurohormone Melatonin: Antioxidant Protection and Neuroendocrine Regulation (1995) (196)
Pineal gland interface between the photoperiodic environment and the endocrine system (1991) (194)
Nocturnal elevation of plasma melatonin and urinary 5-hydroxyindoleacetic acid in young men: attempts at modification by brief changes in environmental lighting and sleep and by autonomic drugs. (1976) (193)
Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection (2018) (192)
Melatonin induces nitric oxide and the potential mechanisms relate to innate immunity against bacterial pathogen infection in Arabidopsis (2015) (190)
Melatonin feedback on clock genes: a theory involving the proteasome (2015) (190)
Action Spectra, Dose‐Response Relationships, and Temporal Aspects of Light's Effects on the Pineal Gland (1985) (189)
A brief survey of pineal gland-immune system interrelationships. (1992) (188)
Physiological levels of melatonin contribute to the antioxidant capacity of human serum (1999) (188)
The influence of different light spectra on the suppression of pineal melatonin content in the syrian hamster (1984) (187)
On the significance of an alternate pathway of melatonin synthesis via 5‐methoxytryptamine: comparisons across species (2016) (186)
Ischemia/reperfusion‐induced arrhythmias in the isolated rat heart: Prevention by melatonin (1998) (186)
Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: Two years' experience (1997) (185)
Novel rhythms of N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation (2007) (184)
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain (2006) (183)
Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland (1984) (183)
Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress (2018) (182)
Neurotoxins: Free Radical Mechanisms and Melatonin Protection (2010) (180)
Augmentation of indices of oxidative damage in life-long melatonin-deficient rats (1999) (180)
The Keap1-Nrf2-antioxidant response element pathway: A review of its regulation by melatonin and the proteasome (2015) (179)
Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling (2015) (178)
Interrelationships of the pineal gland, the superior cervical ganglia and the photoperiod in the regulation of the endocrine systems of hamsters. (1966) (178)
Melatonin enhances thermotolerance by promoting cellular protein protection in tomato plants (2016) (176)
Melatonin: A Versatile Protector against Oxidative DNA Damage (2018) (176)
Melatonin protects human blood lymphocytes from radiation-induced chromosome damage. (1995) (175)
Melatonin mediates selenium‐induced tolerance to cadmium stress in tomato plants (2016) (175)
Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions. (2018) (173)
Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review (2013) (171)
When Melatonin Gets on Your Nerves: Its Beneficial Actions in Experimental Models of Stroke (2005) (170)
Circannual reproductive rhythms in mammals related to photoperiod and pineal function: a review. (1974) (170)
Peripheral Reproductive Organ Health and Melatonin: Ready for Prime Time (2013) (170)
Melatonin inhibition of reproduction in the male hamster: its dependency on time of day of administration and on an intact and sympathetically innervated pineal gland. (1976) (170)
Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies (2011) (170)
Rhythms in immunoreactive melatonin in the retina and Harderian gland of rats: persistence after pinealectomy. (1983) (170)
Pineal control of a seasonal reproductive rhythm in male golden hamsters exposed to natural daylight and temperature. (1973) (169)
Defining chronodisruption (2009) (168)
Melatonin‐induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late‐phase activation of NF‐κB and AP‐1 (2004) (168)
Inhibition of neuronal nitric oxide synthase activity by N1‐acetyl‐5‐methoxykynuramine, a brain metabolite of melatonin (2006) (168)
Phytoremediative Capacity of Plants Enriched with Melatonin (2007) (167)
Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure (2014) (166)
Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats (2013) (166)
The neurohormone melatonin inhibits cytokine, mitogen and ionizing radiation induced NF-kappa B. (1995) (166)
Normal patterns of melatonin levels in the pineal gland and body fluids of humans and experimental animals. (1986) (165)
Melatonin reduces kainate‐induced lipid peroxidation in homogenates of different brain regions (1995) (165)
Melatonin induces class A1 heat‐shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis (2015) (164)
Melatonin, mitochondrial homeostasis and mitochondrial-related diseases. (2002) (164)
Melatonin reduces oxidative stress in surgical neonates. (2004) (163)
Endocrine aspects of the mammalian pineal gland: a review. (1969) (163)
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism (2005) (163)
Evidence for refractoriness of the pituitary‐gonadal axis to the pineal gland in golden hamsters and its possible implications in annual reproductive rhythms (1972) (163)
Melatonin binding sites in the central nervous system (1991) (163)
Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants. (2001) (161)
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair (2008) (160)
HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants (2017) (159)
Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro. (1995) (159)
Protective effects of melatonin in experimental free radical‐related ocular diseases (2006) (157)
The circadian melatonin rhythm and its modulation: possible impact on hypertension (2009) (157)
A review of melatonin as a suitable antioxidant against myocardial ischemia–reperfusion injury and clinical heart diseases (2014) (156)
The role of the thalamus in sleep, pineal melatonin production, and circadian rhythm sleep disorders (2009) (156)
Paraquat toxicity and oxidative damage. Reduction by melatonin. (1996) (155)
Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin. (2004) (155)
Melatonin and the circadian system: contributions to successful female reproduction. (2014) (155)
Static and extremely low frequency electromagnetic field exposure: Reported effects on the circadian production of melatonin (1993) (155)
Mitochondria: the birth place, battle ground and the site of melatonin metabolism in cells (2019) (154)
The suppression of pineal melatonin content and N-acetyltransferase activity by different light irradiances in the Syrian hamster: a dose-response relationship. (1983) (154)
Lipopolysaccharide-induced hepatotoxicity is inhibited by the antioxidant melatonin. (1995) (154)
Melatonin and parkinson’s disease (2005) (153)
Melatonin immunoreactivity in the photosynthetic prokaryote Rhodospirillum rubrum: implications for an ancient antioxidant system. (1995) (153)
Phytomelatonin: a universal abiotic stress regulator (2018) (152)
Function of melatonin in thermoregulatory processes. (1994) (151)
Circadian rhythm in intraocular pressure: a rabbit model. (1981) (151)
Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals. (1996) (150)
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and α‐lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions (2003) (150)
Arabidopsis serotonin N‐acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen (2015) (149)
Role of melatonin in metabolic regulation (2009) (148)
Melatonin receptors: current status, facts, and hypotheses. (1990) (148)
Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling (2016) (148)
Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis (2015) (147)
Prospects of the Clinical Utilization of Melatonin (1998) (147)
Melatonin inhibits telomerase activity in the MCF‐7 tumor cell line both in vivo and in vitro (2003) (146)
DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid. (2001) (145)
Melatonin regulates mesenchymal stem cell differentiation: a review (2014) (144)
Melatonin: Roles in influenza, Covid‐19, and other viral infections (2020) (144)
Melatonin signaling in T cells: Functions and applications (2017) (144)
INDOLE‐3‐ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin‐mediated pathway in Arabidopsis (2015) (144)
Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+‐mediated permeability transition and beyond in rat brain astrocytes (2010) (143)
Chronodisruption and cancer (2008) (143)
Melatonin: Its Inhibition of Pineal Antigonadotrophic Activity in Male Hamsters (1974) (143)
Pineal gland “magnetosensitivity” to static magnetic fields is a consequence of induced electric currents (eddy currents) (1991) (143)
Fundamental Issues Related to the Origin of Melatonin and Melatonin Isomers during Evolution: Relation to Their Biological Functions (2014) (143)
Changes in melatonin levels in transgenic ‘Micro‐Tom’ tomato overexpressing ovine AANAT and ovine HIOMT genes (2014) (142)
Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine (2013) (142)
Melatonin counteracts inducible mitochondrial nitric oxide synthase‐dependent mitochondrial dysfunction in skeletal muscle of septic mice (2006) (142)
Long‐term melatonin treatment delays ovarian aging (2017) (141)
Protection against oxidative protein damage induced by metal-catalyzed reaction or alkylperoxyl radicals: comparative effects of melatonin and other antioxidants. (2003) (141)
Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces (2014) (139)
Melatonin administration prevents lipopolysaccharide‐induced oxidative damage in phenobarbital‐treated animals (1995) (139)
Melatonin and radioprotection from genetic damage: in vivo/in vitro studies with human volunteers. (1996) (139)
Inhibitory effect of melatonin on cataract formation in newborn rats: Evidence for an antioxidative role for melatonin (1994) (138)
Melatonin ameliorates low‐grade inflammation and oxidative stress in young Zucker diabetic fatty rats (2013) (137)
Early indicators of chronic lung disease in preterm infants with respiratory distress syndrome and their inhibition by melatonin (2004) (135)
What constitutes a physiological concentration of melatonin? (2003) (134)
Melatonin induces mitochondrial‐mediated apoptosis in human myeloid HL‐60 cells (2009) (134)
Melatonin Reduces Oxidant Damage and Promotes Mitochondrial Respiration (2002) (133)
Signal transduction pathways involved in melatonin‐induced neuroprotection after focal cerebral ischemia in mice (2005) (133)
Melatonin as a naturally occurring co‐substrate of quinone reductase‐2, the putative MT3 melatonin membrane receptor: hypothesis and significance (2007) (133)
A review of metal‐catalyzed molecular damage: protection by melatonin (2014) (132)
AMPK/PGC1&agr; activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis (2018) (132)
Correlation among cytokines, bronchopulmonary dysplasia and modality of ventilation in preterm newborns: improvement with melatonin treatment (2005) (131)
Melatonin as a Pharmacological Agent against Neuronal Loss in Experimental Models of Huntington's Disease, Alzheimer's Disease and Parkinsonism (1999) (131)
Melatonin: an antioxidant in edible plants. (2002) (131)
Melatonin and human reproduction. (1998) (131)
Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress (2017) (130)
Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases (2015) (130)
Melatonin induces the transcripts of CBF/DREB1s and their involvement in both abiotic and biotic stresses in Arabidopsis (2015) (130)
Pharmacological actions of melatonin in acute and chronic inflammation. (2002) (130)
Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid‐β peptide in rat brain: a comparative, in vivo study versus vitamin C and E (2003) (129)
Acute Exercise Increases Plasma Total Antioxidant Status and Antioxidant Enzyme Activities in Untrained Men (2011) (129)
Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer (2015) (129)
Melatonin and structurally-related, endogenous indoles act as potent electron donors and radical scavengers in vitro. (1996) (129)
Melatonin reduces glial reactivity in the hippocampus, cortex, and cerebellum of streptozotocin-induced diabetic rats. (2003) (128)
Melatonin protects against lipid‐induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice (2017) (128)
Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules (2000) (128)
Therapeutic potential of melatonin related to its role as an autophagy regulator: A review (2018) (127)
The effect of different light intensities on pineal melatonin content (1982) (127)
Melatonin protects hippocampal neurons in vivo against kainic acid‐induced damage in mice (1998) (126)
EFFECT OF MELATONIN ON NF‐κB DNA‐BINDING ACTIVITY IN THE RAT SPLEEN (1996) (126)
Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats. (2007) (125)
Exercise and melatonin in humans: reciprocal benefits (2012) (125)
Melatonin: That Ubiquitously Acting Pineal Hormone (1991) (125)
Melatonin and sirtuins: A “not‐so unexpected” relationship (2017) (124)
Chromium(III)-induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: comparative effects of melatonin, ascorbate, and vitamin E. (2000) (124)
Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. (2002) (124)
Inter‐relationships of the chronobiotic, melatonin, with leptin and adiponectin: implications for obesity (2015) (123)
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice (2008) (123)
Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence (2006) (123)
Exogenous and endogenous control of the annual reproductive cycle in the male golden hamster: participation of the pineal gland. (1975) (123)
Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach (2014) (122)
Quantification of daily melatonin synthesis in the hamster pineal gland. (1980) (122)
Beneficial effects of melatonin in cardiovascular disease (2010) (122)
Melatonin and protection from whole-body irradiation: survival studies in mice. (1999) (122)
Role of melatonin in the regulation of autophagy and mitophagy: A review (2012) (122)
Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells (2010) (122)
Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling (2017) (121)
Melatonin inhibits neural apoptosis induced by homocysteine in hippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro- and anti-apoptotic protein levels (2005) (121)
Interactions of the pineal hormone melatonin with oxygen-centered free radicals: a brief review. (1993) (121)
Long-term sleep disturbances in children: a cause of neuronal loss. (2010) (120)
Pineal indoleamines and vitamin E reduce nitric oxide‐induced lipid peroxidation in rat retinal homogenates (1999) (119)
Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland (2018) (119)
Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways (2017) (119)
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells (2013) (118)
Melatonin as an antibiotic: new insights into the actions of this ubiquitous molecule (2008) (118)
Mechanisms of Melatonin in Alleviating Alzheimer’s Disease (2017) (118)
Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse (2002) (118)
Melatonin protects against maternal obesity‐associated oxidative stress and meiotic defects in oocytes via the SIRT3‐SOD2‐dependent pathway (2017) (117)
Oxidative Damage to Catalase Induced by Peroxyl Radicals: Functional Protection by Melatonin and Other Antioxidants (2003) (117)
Gastric toxicity and mucosal ulceration induced by oxygen-derived reactive species: protection by melatonin. (2001) (117)
Melatonin counteracts lipid peroxidation induced by carbon tetrachloride but does not restore glucose‐6 phosphatase activity (1995) (117)
Marked rapid alterations in nocturnal pineal serotonin metabolism in mice and rats exposed to weak intermittent magnetic fields. (1990) (117)
Melatonin induces pro‐apoptotic signaling pathway in human pancreatic carcinoma cells (PANC‐1) (2010) (117)
Acutely administered melatonin reduces oxidative damage in lung and brain induced by hyperbaric oxygen. (1997) (117)
Comparative physiological and proteomic analyses reveal the actions of melatonin in the reduction of oxidative stress in Bermuda grass (Cynodon dactylon (L). Pers.) (2015) (117)
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation (2018) (117)
Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review. (2015) (116)
Melatonin: potential functions in the oral cavity. (2007) (116)
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota (2018) (116)
Pineal melatonin concentrations in the Syrian hamster. (1979) (115)
Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin. (1995) (115)
Melatonin reduces lipid peroxidation and membrane viscosity (2014) (115)
Melatonin and tryptophan derivatives as free radical scavengers and antioxidants. (1999) (114)
Melatonin Reduces Apoptosis Induced by Calcium Signaling in Human Leukocytes: Evidence for the Involvement of Mitochondria and Bax Activation (2010) (114)
Melatonin and protection from genetic damage in blood and bone marrow: Whole‐body irradiation studies in mice (1999) (113)
Local Melatoninergic System as the Protector of Skin Integrity (2014) (113)
Melatonin combats molecular terrorism at the mitochondrial level (2008) (113)
Melatonin: detoxification of oxygen and nitrogen-based toxic reactants. (2003) (113)
Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver. (2003) (113)
Jerte Valley cherry-enriched diets improve nocturnal rest and increase 6-sulfatoxymelatonin and total antioxidant capacity in the urine of middle-aged and elderly humans. (2010) (112)
Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment (2020) (112)
Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways (2017) (112)
Melatonin protects against isoproterenol‐induced myocardial injury in the rat: antioxidative mechanisms (2010) (110)
Role of Pinoline and Melatonin in Stabilizing Hepatic Microsomal Membranes against Oxidative Stress (1999) (109)
Gene regulation by melatonin linked to epigenetic phenomena. (2012) (109)
The role of the neurohormone melatonin as a buffer against macromolecular oxidative damage (1995) (108)
Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats (2008) (107)
Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice (2007) (107)
Evidence that membrane‐bound G protein‐coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia (2012) (107)
Biogenic amines in the reduction of oxidative stress: melatonin and its metabolites. (2008) (106)
Melatonin prevents increases in neural nitric oxide and cyclic GMP production after transient brain ischemia and reperfusion in the Mongolian gerbil (Meriones Unguiculatus) (1997) (106)
Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium‐dependent translocation of Drp1 to the mitochondria (2016) (105)
Melatonin in edible plants (phytomelatonin): Identification, concentrations, bioavailability and proposed functions. (2007) (105)
Melatonin protects against stress‐induced gastric lesions by scavenging the hydroxyl radical (2000) (104)
High affinity of sigma1‐binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8–C7 isomerase (1997) (104)
Protective action of melatonin against oxidative DNA damage: chemical inactivation versus base-excision repair. (2007) (104)
Pineal serotonin-N-acetyltransferase activity in four mammalian species (1975) (103)
Melatonin reduces oxidative neurotoxicity due to quinolinic acid: in vitro and in vivo findings (2000) (103)
Diabetes and Alzheimer Disease, Two Overlapping Pathologies with the Same Background: Oxidative Stress (2015) (102)
Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage. (2007) (101)
Oxidative Stress-Mediated Aging during the Fetal and Perinatal Periods (2014) (101)
Matrix metalloproteinases in health and disease: regulation by melatonin (2011) (101)
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes (2018) (100)
Purslane: a plant source of omega‐3 fatty acids and melatonin (2005) (100)
Melatonin regulates glucocorticoid receptor: an answer to its antiapoptotic action in thymus (1999) (100)
Therapeutic potential of melatonin in traumatic central nervous system injury (2009) (100)
Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues of chick and their inhibition by light (2001) (100)
Melatonin Regulates Root Meristem by Repressing Auxin Synthesis and Polar Auxin Transport in Arabidopsis (2016) (99)
Pineal melatonin in syrian hamsters: circadian and seasonal rhythms in animals maintained under laboratory and natural conditions. (1982) (99)
Light, timing of biological rhythms, and chronodisruption in man (2003) (98)
Melatonin's Role as an Anticonvulsant and Neuronal Protector: Experimental and Clinical Evidence (1998) (98)
Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiation (2010) (98)
Melatonin alleviates low PS I‐limited carbon assimilation under elevated CO2 and enhances the cold tolerance of offspring in chlorophyll b‐deficient mutant wheat (2018) (97)
Melatonin inhibits matrix metalloproteinase‐9 activity by binding to its active site (2013) (97)
Melatonin inhibits free radical‐mediated mitochondrial‐dependent hepatocyte apoptosis and liver damage induced during malarial infection (2007) (97)
Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK‐MEL‐1 cells (2010) (96)
Melatonin reduces endothelin‐1 expression and secretion in colon cancer cells through the inactivation of FoxO‐1 and NF‐κβ (2014) (96)
Significance of High Levels of Endogenous Melatonin in Mammalian Cerebrospinal Fluid and in the Central Nervous System (2010) (96)
Melatonin Its intracellular and genomic actions (1996) (96)
Melatonin as a potential anticarcinogen for non-small-cell lung cancer (2016) (94)
Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging (2020) (94)
Natural Variation in Banana Varieties Highlights the Role of Melatonin in Postharvest Ripening and Quality. (2017) (94)
Melatonin suppresses TPA‐induced metastasis by downregulating matrix metalloproteinase‐9 expression through JNK/SP‐1 signaling in nasopharyngeal carcinoma (2016) (94)
Melatonin and vitamin E limit nitric oxide-induced lipid peroxidation in rat brain homogenates (1997) (93)
The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF‐α toxicity involves membrane melatonin receptors (2010) (93)
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail (2013) (92)
Pineal function in long term blinded male and female golden hamsters. (1969) (92)
Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis. (2003) (92)
Melatonin increases brown adipose tissue mass and function in Zücker diabetic fatty rats: implications for obesity control (2018) (92)
Melatonin delays leaf senescence of Chinese flowering cabbage by suppressing ABFs‐mediated abscisic acid biosynthesis and chlorophyll degradation (2019) (92)
Melatonin Relieves the Neural Oxidative Burden that Contributes to Dementias (2004) (91)
Pineal opioid receptors and analgesic action of melatonin (1998) (91)
Melatonin Suppression by Static and Extremely Low Frequency Electromagnetic Fields: Relationship to the Reported Increased Incidence of Cancer (1994) (90)
Melatonin: the dawning of a treatment for fibrosis? (2016) (90)
Melatonin, a mediator of electron transfer and repair reactions, acts synergistically with the chain-breaking antioxidants ascorbate, trolox and glutathione (1995) (90)
Melatonin protects against oxidative damage and restores expression of GLUT4 gene in the hyperthyroid rat heart (2007) (90)
Melatonin as a treatment for gastrointestinal cancer: a review (2015) (89)
Melatonin and mitochondrial function during ischemia/reperfusion injury (2017) (89)
A new balancing act: The many roles of melatonin and serotonin in plant growth and development (2015) (89)
Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes. (1998) (89)
Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth. (1988) (89)
Observations on the pineal gland, the Harderian glands, the retina, and the reproductive organs of adult female rats exposed to continuous light. (1971) (88)
Novel bromomelatonin derivatives as potentially effective drugs to treat bone diseases (2008) (88)
Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants. (2006) (88)
Melatonin Enhances Tamoxifen's Ability to Prevent the Reduction in Microsomal Membrane Fluidity Induced by Lipid Peroxidation (1998) (88)
Melatonin in diseases of the oral cavity. (2010) (88)
Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. (2003) (87)
Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis (2019) (87)
The fine structure of the hamster pineal gland. (1968) (86)
Suppressive effect of melatonin administration on ethanol‐induced gastroduodenal injury in rats in vivo (1997) (86)
Histophysiological evidence for the secretion of polypeptides by the pineal gland. (1975) (86)
Protective Role of Melatonin in Neonatal Diseases (2013) (86)
Melatonin uses in oncology: breast cancer prevention and reduction of the side effects of chemotherapy and radiation (2012) (86)
Resynchronization of hormonal rhythms after an eastbound flight in humans: effects of slow-release caffeine and melatonin (2001) (86)
Melatonin administration lowers biomarkers of oxidative stress and cardio-metabolic risk in type 2 diabetic patients with coronary heart disease: A randomized, double-blind, placebo-controlled trial. (2019) (85)
Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. (2007) (85)
Harderian Glands of Golden Hamsters: Temporal and Sexual Differences in Immunoreactive Melatonin (1985) (85)
Prophylactic Actions of Melatonin in Oxidative Neurotoxicity (1997) (85)
Pro-oxidant effect of melatonin in tumour leucocytes: relation with its cytotoxic and pro-apoptotic effects. (2011) (85)
Role of Melatonin and Pineal Peptides in Neuroimmunomodulation (1991) (85)
Inhibition of proliferation and induction of apoptosis by melatonin in human myeloid HL‐60 cells (2007) (85)
Food restriction retards aging of the pineal gland (1991) (84)
Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: A therapeutic target to reduce intestinal inflammation (2020) (84)
Melatonin: reducing molecular pathology and dysfunction due to free radicals and associated reactants. (2002) (84)
Melatonin administration to wild‐type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis (2017) (84)
Inhibiting MT2‐TFE3‐dependent autophagy enhances melatonin‐induced apoptosis in tongue squamous cell carcinoma (2018) (83)
Melatonin protects against piroxicam‐induced gastric ulceration (2004) (83)
Oxidative stress in relation to surgery: is there a role for the antioxidant melatonin? (2009) (83)
Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19 (2020) (83)
Role of melatonin in controlling angiogenesis under physiological and pathological conditions (2019) (83)
Clinical Uses of Melatonin in Pediatrics (2011) (83)
Effect of chronic nicotine administration on the rat lung and liver: beneficial role of melatonin. (2007) (83)
Melatonin down‐regulates MDM2 gene expression and enhances p53 acetylation in MCF‐7 cells (2014) (83)
The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates (1998) (82)
Melatonin: The smart killer The human trophoblast as a model (2012) (82)
Melatonin and its metabolites ameliorate ultraviolet B‐induced damage in human epidermal keratinocytes (2014) (82)
Oxygen radical detoxification processes during aging:The functional importance of melatonin (1995) (81)
Update on the use of melatonin in pediatrics (2011) (81)
Melatonin rhythms in Arctic urban residents (1994) (81)
Light/dark patterns of interleukin-6 in relation to the pineal hormone melatonin in patients with acute myocardial infarction. (2004) (81)
Comparative metabolomic analysis highlights the involvement of sugars and glycerol in melatonin-mediated innate immunity against bacterial pathogen in Arabidopsis (2015) (80)
The role of melatonin, a multitasking molecule, in retarding the processes of ageing (2018) (80)
Metabolism of melatonin in the skin: Why is it important? (2017) (80)
Protective role of melatonin in progesterone production by human luteal cells (2011) (80)
Scientific Basis for the Potential Use of Melatonin in Bone Diseases: Osteoporosis and Adolescent Idiopathic Scoliosis (2010) (79)
Pain in neonatal intensive care: role of melatonin as an analgesic antioxidant (2012) (79)
Essential actions of melatonin in protecting the ovary from oxidative damage. (2014) (79)
Melatonin in relation to the antioxidative defense and immune systems: possible implications for cell and organ transplantation (1999) (79)
Melatonin: possible mechanisms involved in its 'radioprotective' effect. (1998) (79)
Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19 (2020) (78)
Melatonin reduces indomethacin‐induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis (2009) (78)
Effect of melatonin and other pineal indoles on adrenal enlargement produced in male and female mice by pinealectomy, unilateral adrenalectomy, castration, and cold stress. (1972) (78)
Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration. (1999) (78)
Induction of lipid peroxidation in hamster organs by the carcinogen cadmium: amelioration by melatonin (2004) (78)
Melatonin Attenuates Potato Late Blight by Disrupting Cell Growth, Stress Tolerance, Fungicide Susceptibility and Homeostasis of Gene Expression in Phytophthora infestans (2017) (78)
Involvement of reactive oxygen species in gastric ulceration: protection by melatonin. (2002) (78)
Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats (2015) (77)
Resveratrol is a promising agent for colorectal cancer prevention and treatment: focus on molecular mechanisms (2019) (77)
Brief report: melatonin-related hypogonadotropic hypogonadism. (1992) (77)
Effect of light irradiance and wavelength on the Syrian hamster reproductive system. (1986) (77)
The pineal gland: An intermediary between the environment and the endocrine system (1983) (77)
Analgesic, Anxiolytic and Anaesthetic Effects of Melatonin: New Potential Uses in Pediatrics (2015) (77)
Role of melatonin in the epigenetic regulation of breast cancer (2009) (77)
Melatonin stimulates osteointegration of dental implants (2008) (77)
Effect of melatonin on NF-kappa-B DNA-binding activity in the rat spleen. (1996) (76)
Molecular mechanisms of melatonin’s inhibitory actions on breast cancers (2013) (75)
Melatonin and its atheroprotective effects: A review (2014) (75)
Identification, transcriptional and functional analysis of heat‐shock protein 90s in banana (Musa acuminata L.) highlight their novel role in melatonin‐mediated plant response to Fusarium wilt (2017) (75)
A unicenter, randomized, double-blind, parallel-group, placebo-controlled study of Melatonin as an Adjunct in patients with acute myocaRdial Infarction undergoing primary Angioplasty The Melatonin Adjunct in the acute myocaRdial Infarction treated with Angioplasty (MARIA) trial: study design and rat (2007) (75)
Characterization of the protective effects of melatonin and related indoles against α‐naphthylisothiocyanate‐induced liver injury in rats (2001) (74)
The photoperiod, circadian regulation and chronodisruption: the requisite interplay between the suprachiasmatic nuclei and the pineal and gut melatonin. (2011) (74)
A generalized theory of carcinogenesis due to chronodisruption. (2008) (74)
Clinical relevance of melatonin in ovarian and placental physiology: a review (2014) (74)
Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase‐3 and is suitable as an add‐on treatment to tissue‐plasminogen activator (2004) (74)
Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation. (2003) (73)
Pineal antigonadotrophic substances: polypeptides and indoles. (1977) (73)
Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy. (1987) (73)
Melatonin identified in meats and other food stuffs: potentially nutritional impact (2014) (73)
Melatonin protects hepatic mitochondrial respiratory chain activity in senescence‐accelerated mice (2002) (73)
Pineal, retinal and harderian gland melatonin in a diurnal species, the richardson's ground squirrel (Spermophilus richardsonii) (1981) (73)
An evolutionary view of melatonin synthesis and metabolism related to its biological functions in plants. (2020) (73)
Melatonin reduces H2O2‐induced lipid peroxidation in homogenates of different rat brain regions (1995) (72)
Melatonin reduces the need for sedation in ICU patients: a randomized controlled trial. (2015) (72)
Prophylactic use of melatonin protects against focal cerebral ischemia in mice: role of endothelin converting enzyme‐1 (2004) (72)
Role of melatonin in regulating matrix metalloproteinase‐9 via tissue inhibitors of metalloproteinase‐1 during protection against endometriosis (2008) (72)
Melatonin as a pharmacological agent against oxidative damage to lipids and DNA. (1998) (72)
Effect of intravenous and intracoronary melatonin as an adjunct to primary percutaneous coronary intervention for acute ST‐elevation myocardial infarction: Results of the Melatonin Adjunct in the acute myocaRdial Infarction treated with Angioplasty trial (2017) (72)
Melatonin in the oral cavity: physiological and pathological implications. (2015) (72)
Acute Lung Injury: the therapeutic role of Rho kinase inhibitors. (2020) (72)
Magnetic field effects on pineal indoleamine metabolism and possible biological consequences (1992) (72)
Melatonin and its derivatives counteract the ultraviolet B radiation‐induced damage in human and porcine skin ex vivo (2018) (72)
Clinical aspects of melatonin. (2008) (71)
The multiple functions of melatonin in regenerative medicine (2018) (71)
Ischemic brain injury: New insights on the protective role of melatonin. (2017) (71)
Melatonin inhibits fatty acid-induced triglyceride accumulation in ROS17/2.8 cells: implications for osteoblast differentiation and osteoporosis. (2007) (71)
Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3 (2018) (70)
Pineal function during aging: attenuation of the melatonin rhythm and its neurobiological consequences. (1994) (70)
Depressed nocturnal plasma melatonin levels in drug-free paranoid schizophrenics (1992) (70)
Indole‐3‐propionic acid, a melatonin‐related molecule, protects hepatic microsomal membranes from iron‐induced oxidative damage: Relevance to cancer reduction (2001) (70)
Tryptophan loading increases daytime serum melatonin levels in intact and pinealectomized rats. (1993) (70)
N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the Harderian glands of the female Syrian hamster: changes during the light:dark cycle and the effect of 6-parachlorophenylalanine administration. (1987) (70)
Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”? (2012) (70)
Light-Mediated Perturbations of Circadian Timing and Cancer Risk: A Mechanistic Analysis (2009) (70)
Responses of some endocrine organs of female hamsters to pinealectomy and light. (1966) (70)
Role of melatonin on production and preservation of gametes and embryos: a brief review. (2014) (70)
Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period (2012) (69)
Melatonin Reduces Lipid Peroxidation and Tissue Edema in Cerulein-Induced Acute Pancreatitis in Rats (1999) (69)
Melatonin treatment in peri‐ and postmenopausal women elevates serum high‐density lipoprotein cholesterol levels without influencing total cholesterol levels (2008) (69)
Tissue‐plasminogen activator‐induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt (2005) (69)
Cyclic-3-hydroxymelatonin (C3HOM), a potent antioxidant, scavenges free radicals and suppresses oxidative reactions. (2014) (69)
Melatonin in Mitochondria: Mitigating Clear and Present Dangers. (2020) (69)
Local application of melatonin into alveolar sockets of beagle dogs reduces tooth removal-induced oxidative stress. (2007) (69)
Elevated levels of oxidized low-density lipoprotein and impaired nocturnal synthesis of melatonin in patients with myocardial infarction. (2005) (69)
Ebola virus disease: potential use of melatonin as a treatment (2014) (69)
Analysis of the daily changes of melatonin receptors in the rat liver (2013) (69)
Pineal methoxyindoles: new evidence concerning their function in the control of pineal-mediated changes in the reproductive physiology of male golden hamsters. (1975) (69)
24-Hour changes in catecholamine synthesis in rat and hamster pineal glands. (1984) (68)
Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review (2016) (68)
Lipopolysaccharide-induced DNA damage is greatly reduced in rats treated with the pineal hormone melatonin (1996) (68)
Alterations of the circadian melatonin rhythm by the electromagnetic spectrum: a study in environmental toxicology. (1992) (68)
Do magnetic fields cause increased risk of childhood leukemia via melatonin disruption? (2005) (68)
Phytomelatonin: An Emerging Regulator of Plant Biotic Stress Resistance. (2020) (67)
Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury (2010) (67)
The protective role of endogenous melatonin in carrageenan‐induced pleurisy in the rat (1999) (67)
Accumulation of Exogenous Amyloid-Beta Peptide in Hippocampal Mitochondria Causes Their Dysfunction: A Protective Role for Melatonin (2012) (67)
Melatonin Improves the Photosynthetic Apparatus in Pea Leaves Stressed by Paraquat via Chlorophyll Breakdown Regulation and Its Accelerated de novo Synthesis (2017) (67)
Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition (2018) (67)
Melatonin, Longevity and Health in the Aged: An Assessment (2002) (67)
Neuroendocrine effects of light (1991) (67)
Evidence that extremely low frequency Ca2+-cyclotron resonance depresses pineal melatonin synthesis in vitro (1991) (66)
Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1 (2017) (66)
Cyclic 3-Hydroxymelatonin: A Melatonin Metabolite Generated as a Result of Hydroxyl Radical Scavenging (1999) (66)
Melatonin Application to Pisum sativum L. Seeds Positively Influences the Function of the Photosynthetic Apparatus in Growing Seedlings during Paraquat-Induced Oxidative Stress (2016) (66)
Melatonin antagonizes cadmium‐induced neurotoxicity by activating the transcription factor EB‐dependent autophagy–lysosome machinery in mouse neuroblastoma cells (2016) (66)
Melatonin : a universal photoperiodic signal with diverse actions (1996) (66)
Light Hygiene: Time to make preventive use of insights--old and new--into the nexus of the drug light, melatonin, clocks, chronodisruption and public health. (2009) (66)
Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation (2000) (66)
Clinical aspects of melatonin in the acute coronary syndrome. (2009) (65)
Predominance of 2‐hydroxymelatonin over melatonin in plants (2015) (65)
Melatonin protects against gastric ulceration and increases the efficacy of ranitidine and omeprazole in reducing gastric damage (2002) (65)
Treatment of ebola and other infectious diseases: melatonin “goes viral” (2020) (65)
Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: Preventive actions of melatonin (1997) (65)
Melatonin Ameliorates Neurologic Damage and Neurophysiologic Deficits in Experimental Models of Stroke (2003) (65)
Alterations in components of the pineal melatonin synthetic pathway by acute insulin stress in the rat and Syrian hamster (1985) (65)
Melatonin promotes angiogenesis during protection and healing of indomethacin‐induced gastric ulcer: role of matrix metaloproteinase‐2 (2010) (65)
A new perspective in Oral health: potential importance and actions of melatonin receptors MT1, MT2, MT3, and RZR/ROR in the oral cavity. (2011) (64)
Hepatic mitochondrial dysfunction in senescence‐accelerated mice: correction by long‐term, orally administered physiological levels of melatonin (2002) (64)
Melatonin in the lacrimal gland: first demonstration and experimental manipulation. (1988) (64)
Oxidative toxicity in models of neurodegeneration: responses to melatonin. (1998) (64)
Cytoprotective properties of melatonin: presumed association with oxidative damage and aging. (1998) (64)
Melatonin: A Multifunctional Molecule That Triggers Defense Responses against High Light and Nitrogen Starvation Stress in Haematococcus pluvialis. (2018) (64)
Acutely administered melatonin restores hepatic mitochondrial physiology in old mice. (2003) (64)
Yeast sterol C8-C7 isomerase: identification and characterization of a high-affinity binding site for enzyme inhibitors. (1996) (63)
Protective effect of melatonin against hippocampal injury of rats with intermittent hypoxia (2008) (63)
Pharmacological Analysis of Sterol Δ8-Δ7 Isomerase Proteins with [3H]Ifenprodil (1998) (63)
Melatonin protects against isoproterenol‐induced alterations in cardiac mitochondrial energy‐metabolizing enzymes, apoptotic proteins, and assists in complete recovery from myocardial injury in rats (2012) (63)
Protection of melatonin in experimental models of newborn hypoxic‐ischemic brain injury through MT1 receptor (2018) (63)
Breast cancer, blindness and melatonin. (1992) (63)
Melatonin stabilizes rupture‐prone vulnerable plaques via regulating macrophage polarization in a nuclear circadian receptor RORα‐dependent manner (2019) (63)
Beneficial effects of melatonin in protecting against cyclosporine A‐induced cardiotoxicity are receptor mediated (2006) (62)
Variation in Pineal Melatonin Content during the Estrous Cycle of the Rat (1982) (62)
Protective role of melatonin against MPTP-induced mouse brain cell DNA fragmentation and apoptosis in vivo. (2001) (62)
Relative efficacies of indole antioxidants in reducing autoxidation and iron‐induced lipid peroxidation in hamster testes (2001) (62)
Differential response of pineal melatonin levels to light at night in laboratory-raised and wild-captured 13-lined ground squirrels (Spermophilus tridecemlineatus). (1983) (62)
Sleep and cancer: Synthesis of experimental data and meta-analyses of cancer incidence among some 1,500,000 study individuals in 13 countries (2016) (62)
Pineal Melatonin Content in Male Hamsters throughout the Seasonal Reproductive Cycle 1 (1980) (61)
A comparison of the action of amifostine and melatonin on DNA‐damaging effects and apoptosis induced by idarubicin in normal and cancer cells (2005) (61)
Melatonin and Atopy: Role in Atopic Dermatitis and Asthma (2014) (61)
Melatonin and its derivatives cyclic 3‐hydroxymelatonin, N1‐acetyl‐N2‐formyl‐5‐methoxykynuramine and 6‐methoxymelatonin reduce oxidative DNA damage induced by Fenton reagents (2003) (61)
The Pineal and reproduction (1978) (61)
Melatonin's role as a co‐adjuvant treatment in colonic diseases: A review (2017) (61)
Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics. (2021) (61)
Melatonin induces apoptosis through a caspase‐dependent but reactive oxygen species‐independent mechanism in human leukemia Molt‐3 cells (2013) (61)
Functional aspects of redox control during neuroinflammation. (2010) (60)
Cytoprotective effects of melatonin on C6 astroglial cells exposed to glutamate excitotoxicity and oxidative stress (2008) (60)
Comparison of the protective effect of melatonin with other antioxidants in the hamster kidney model of estradiol-induced DNA damage. (2001) (60)
In vivo and in vitro effects of the pineal gland and melatonin on [Ca2++ Mg2+]‐dependent ATPase in cardiac sarcolemma (1993) (60)
Preliminary observations on the reproductive effects of the pineal gland in blinded, anosmic male rats. (1969) (60)
Oxidative stress in resuscitation and in ventilation of newborns (2009) (60)
Evaluating the protective effects of melatonin on di(2-ethylhexyl) phthalate-induced testicular injury in adult mice. (2018) (60)
Experimental models of melatonin-deficient hypertension. (2013) (59)
Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells: A Mechanistic Analysis (2020) (59)
Changes in the reporductive organs of cold-exposed and light-deprived female hamsters (Mesocricetus auratus). (1968) (59)
Melatonin therapy in fibromyalgia (2007) (59)
Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats (2014) (59)
Emergence of naturally occurring melatonin isomers and their proposed nomenclature (2012) (59)
Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63. (2013) (59)
Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell‐free systems by melatonin (2005) (58)
Aging and oxygen toxicity: Relation to changes in melatonin (1997) (58)
Aging and vascular dysfunction: beneficial melatonin effects (2013) (58)
Effect of melatonin on the severity of L-arginine-induced experimental acute pancreatitis in rats. (2004) (58)
The fine structure of the pineal gland in the pocket gopher, Geomys bursarius. (1973) (58)
Melatonin and the von Hippel-Lindau/HIF-1 oxygen sensing mechanism: A review. (2016) (58)
H2O2 induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonin (1995) (58)
Melatonin as a proteasome inhibitor. Is there any clinical evidence? (2014) (58)
Pineal indoles: production, secretion and actions (1984) (58)
The Influence of Various Irradiances of Artificial Light, Twilight, and Moonlight on the Suppression of Pineal Melatonin Content in the Syrian Hamster (1984) (58)
Critical role of glutathione in melatonin enhancement of tumor necrosis factor and ionizing radiation‐induced apoptosis in prostate cancer cells in vitro (2008) (58)
Retracted: HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways (2015) (58)
Idiopathic pulmonary fibrosis (IPF) signaling pathways and protective roles of melatonin (2018) (57)
Interactions of pinealectomy and short-photoperiod exposure on the neuroendocrine axis of the male Syrian hamster. (1984) (57)
Clinical Uses of Melatonin in Neurological Diseases and Mental and Behavioural Disorders. (2017) (57)
The Effect of Pineal Grafts, Pinealectomy, and Denervation of the Pineal Gland on the Reproductive Organs of Male Hamsters (1967) (57)
The pineal gland and gonadal development in male rats and hamsters. (1968) (57)
Reproductive effects of the mammalian pineal. (1970) (57)
Depressant action of the pineal gland on pituitary luteinizing hormone and prolactin in male hamsters. (1974) (57)
Time course of the melatonin-induced increase in glutathione peroxidase activity in chick tissues. (1995) (57)
Melatonin: The watchdog of villous trophoblast homeostasis against hypoxia/reoxygenation-induced oxidative stress and apoptosis (2013) (57)
Interactions of the pineal gland, blinding, and underfeeding on reproductive organ size and radioimmunoassayable growth hormone. (1971) (57)
Reactive Oxygen Species and the Hypomotility of the Gall Bladder as Targets for the Treatment of Gallstones with Melatonin: A Review (2008) (57)
BOTH MELATONIN AND A PUTATIVE NUCLEAR MELATONIN RECEPTOR AGONIST CGP 52608STIMULATE GLUTATHIONE PEROXIDASE AND GLUTATHIONE REDUCTASE ACTIVITIES IN MO USE BRAIN IN VIVO (1997) (56)
Photoreceptor damage and eye pigmentation: influence on the sensitivity of rat pineal N-acetyltransferase activity and melatonin levels to light at night. (1985) (56)
Melatonin protects against lipid peroxidation induced by δ-aminolevulinic acid in rat cerebellum, cortex and hippocampus (1997) (56)
Cyclic 3-hydroxymelatonin, a key metabolite enhancing the peroxyl radical scavenging activity of melatonin (2014) (56)
Influence of Compensatory Mechanisms and the Pineal Gland on Dark-induced Gonadal Atrophy in Male Hamsters (1965) (56)
Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: implications for liver transplantation (2005) (56)
Usefulness of Early Treatment With Melatonin to Reduce Infarct Size in Patients With ST-Segment Elevation Myocardial Infarction Receiving Percutaneous Coronary Intervention (From the Melatonin Adjunct in the Acute Myocardial Infarction Treated With Angioplasty Trial). (2017) (56)
Protective effects of melatonin against thioacetamide-induced liver fibrosis in rats. (2015) (56)
Influence of pinealectomy on the breeding capability of hamsters maintained under natural photoperiodic and temperature conditions. (1973) (56)
Effect of melatonin on secreted and induced matrix metalloproteinase‐9 and ‐2 activity during prevention of indomethacin‐induced gastric ulcer (2005) (56)
Specific binding of 2-[125I]melatonin by partially purified membranes of rat thymus (1993) (55)
Age-related changes in the intact and sympathetically denervated gerbil pineal gland. (1976) (55)
Melatonin as a potential therapeutic agent in psychiatric illness (2009) (55)
Mitochondrial and Metabolic Dysfunction in Renal Convoluted Tubules of Obese Mice: Protective Role of Melatonin (2014) (55)
Melatonin: A new inhibitor agent for cervical cancer treatment (2019) (55)
Pineal sensitivity to pulsed static magnetic fields changes during the photoperiod (1993) (55)
Melatonin: Protection against age-related cardiac pathology (2017) (55)
Interferon-γ Modulates Melatonin Production in Rat Pineal Glands in Organ Culture (1990) (55)
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. (1999) (55)
Antitumour activity of melatonin in a mouse model of human prostate cancer: relationship with hypoxia signalling (2014) (54)
Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin (2010) (54)
Melatonin as a promising agent to treat ovarian cancer: molecular mechanisms. (2017) (54)
Antioxidant strategies in protection against neurodegenerative disorders (2003) (54)
CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal. (2016) (54)
Daily differential expression of melatonin‐related genes and clock genes in rat cumulus–oocyte complex: changes after pinealectomy (2015) (54)
Melatonin reduces phenylhydrazine-induced oxidative damage to cellular membranes: evidence for the involvement of iron. (2000) (54)
Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging. (2008) (54)
Thyroxine 5'-deiodinase activity in pineal gland and frontal cortex: nighttime increase and the effect of either continuous light exposure or superior cervical ganglionectomy. (1988) (54)
Melatonin receptors in purified cell nuclei of liver. (1993) (54)
Some endocrine effects of blinding and anosmia in adult male rats with observations on pineal melatonin. (1971) (54)
Decreased level of melatonin in serum predicts left ventricular remodelling after acute myocardial infarction (2012) (54)
Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice (2013) (54)
Melatonin disrupts circadian rhythms of glutamate and GABA in the neostriatum of the awake rat: a microdialysis study (2000) (54)
Mechanisms of isoproterenol‐induced cardiac mitochondrial damage: protective actions of melatonin (2015) (53)
Melatonin Absence Leads to Long-Term Leptin Resistance and Overweight in Rats (2018) (53)
Melatonin and cardiovascular disease: myth or reality? (2012) (53)
Subcutaneous melatonin implants inhibit reproductive atrophy in male hamsters induced by daily melatonin injections. (1977) (53)
Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney. (1999) (53)
Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells (2019) (53)
The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health. (2019) (53)
Inconsistent suppression of nocturnal pineal melatonin synthesis and serum melatonin levels in rats exposed to pulsed DC magnetic fields. (1998) (53)
Melatonin and aging. (2002) (53)
Kinetics of the neuroinflammation-oxidative stress correlation in rat brain following the injection of fibrillar amyloid-β onto the hippocampus in vivo (2004) (53)
Melatonin synthesis impairment as a new deleterious outcome of diabetes‐derived hyperglycemia (2014) (53)
Daily rhythms of phytomelatonin signaling modulate diurnal stomatal closure via regulating reactive oxygen species dynamics in Arabidopsis (2020) (52)
Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment (2007) (52)
A review of the melatonin functions in zebrafish physiology (2014) (52)
Potential Utility of Melatonin in Preeclampsia, Intrauterine Fetal Growth Retardation, and Perinatal Asphyxia (2016) (52)
Utility of melatonin to treat surgical stress after major vascular surgery – a safety study (2008) (52)
Pineal biosynthetic activity and neuroendocrine physiology in the aging hamster and gerbil (1980) (52)
Melatonin reduces oxidative/nitrosative stress due to drugs, toxins, metals, and herbicides. (2008) (52)
Melatonin treatment improves primary progressive multiple sclerosis: a case report (2015) (51)
Oxidative/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis (2018) (51)
Norepinephrine or isoproterenol stimulation of pineal N-acetyltransferase activity and melatonin content in the Syrian hamster is restricted to the second half of the daily dark phase. (1987) (51)
Circadian mechanisms in the regulation of melatonin synthesis: disruption with light at night and the pathophysiological consequences - (2011) (51)
Melatonin reduces the oxidation of nuclear DNA and membrane lipids induced by the carcinogen δ‐aminolevulinic acid (2000) (51)
Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans (2013) (51)
Stress response and procedural pain in the preterm newborn: the role of pharmacological and non-pharmacological treatments (2012) (51)
Melatonin, bone regulation and the ubiquitin-proteasome connection: A review. (2016) (51)
Melatonin as pharmacologic support in burn patients: A proposed solution to thermal injury–related lymphocytopenia and oxidative damage (2007) (51)
Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival (2019) (51)
Role of CSF in the transport of melatonin (2002) (50)
Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms (2019) (50)
Physiological ischemia/reperfusion phenomena and their relation to endogenous melatonin production (2005) (50)
Characterization of type-II thyroxine 5'-deiodinase activity in rat Harderian gland. (1987) (50)
Swimming depresses nighttime melatonin content without changing N-acetyltransferase activity in the rat pineal gland. (1988) (50)
Experimentally-induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster. (1983) (50)
A single 1- or 5-second light pulse at night inhibits hamster pineal melatonin. (1986) (49)
Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin (2013) (49)
A novel role for melatonin: regulation of the expression of cell adhesion molecules in the rat hippocampus and cortex (2002) (49)
N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin. (2015) (49)
Physiological concentrations of melatonin inhibit the norepinephrine‐induced activation of prostaglandin E2 and cyclic AMP production in rat hypothalamus: A mechanism involving inhibition of nitric oxide synthase (1998) (49)
Potential biological consequences of excessive light exposure: melatonin suppression, DNA damage, cancer and neurodegenerative diseases. (2002) (49)
Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis (2016) (49)
Association of ischemia-modified albumin and melatonin in patients with ST-elevation myocardial infarction. (2008) (49)
Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model (2009) (48)
The effects of pineal indoles given late in the light period on reproductive organs and pituitary prolactin levels in male golden hamsters. (1977) (48)
Effect of melatonin on mitotic and proliferation indices, and sister chromatid exchange in human blood lymphocytes. (1996) (48)
Melatonin Protects Against Oxidative Stress Caused by δ-Aminolevulinic Acid: Implications for Cancer Reduction (2002) (48)
Promising Antineoplastic Actions of Melatonin (2018) (48)
Molecular cloning of melatonin 3‐hydroxylase and its production of cyclic 3‐hydroxymelatonin in rice (Oryza sativa) (2016) (48)
REVIEW ARTICLE: Melatonin plus exercise‐based neurorehabilitative therapy for spinal cord injury (2010) (48)
Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair (2012) (48)
Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age. (2009) (48)
Inhibition of mitochondrial pyruvate dehydrogenase kinase: a proposed mechanism by which melatonin causes cancer cells to overcome cytosolic glycolysis, reduce tumor biomass and reverse insensitivity to chemotherapy (2019) (47)
Curcumin and its analogues protect from endoplasmic reticulum stress: mechanisms and pathways. (2019) (47)
Prolactin-releasing and release-inhibiting factor activities in the bovine, rat, and human pineal gland: in vitro and in vivo studies. (1976) (47)
Melatonin as adjuvant treatment for coronavirus disease 2019 pneumonia patients requiring hospitalization (MAC-19 PRO): a case series (2020) (47)
Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. (2019) (47)
Elderly as a High-risk Group during COVID-19 Pandemic: Effect of Circadian Misalignment, Sleep Dysregulation and Melatonin Administration (2020) (47)
A review of neuroendocrine and neurochemical changes associated with static and extremely low frequency electromagnetic field exposure (1993) (47)
Melatonin given in the morning prevents the suppressive action on the reproductive system of melatonin given in late afternoon. (1980) (47)
Melatonin Reduces Angiogenesis in Serous Papillary Ovarian Carcinoma of Ethanol-Preferring Rats (2017) (46)
Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC‐1β: In vivo and in vitro studies (2017) (46)
Effects of melatonin on thyroid physiology of female hamsters. (1982) (46)
Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by delta-aminolevulinic acid. (2000) (46)
Melatonin, active oxygen species and neurological damage. (1998) (46)
Ultrastructural observations at pineal gland capillaries in four rodent species. (1975) (46)
Melatonin enhances hyperthermia‐induced apoptotic cell death in human leukemia cells (2016) (45)
Neurally-mediated and neurally-independent beneficial actions of melatonin in the gastrointestinal tract. (2003) (45)
Synergistic anti‐oomycete effect of melatonin with a biofungicide against oomycetic black shank disease (2018) (45)
ALDH2 contributes to melatonin-induced protection against APP/PS1 mutation-prompted cardiac anomalies through cGAS-STING-TBK1-mediated regulation of mitophagy (2020) (45)
Presence and effects of melatonin in Trypanosoma cruzi (1999) (45)
Sexual Dimorphism in N-Acetyltransferase Activity, Hydroxyindole-O-methyltransferase Activity, and Melatonin Content in the Harderian Gland of Syrian Hamsters: Changes following Gonadectomy 1 (1988) (45)
Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats (2004) (45)
An interesting anatomical relationship between the hamster pineal gland and the ventricular system of the brain. (1969) (45)
Melatonin is able to delay endoplasmic reticulum stress-induced apoptosis in leukocytes from elderly humans (2011) (45)
Drug-mediated ototoxicity and tinnitus: alleviation with melatonin. (2011) (45)
The absence of maternal pineal melatonin rhythm during pregnancy and lactation impairs offspring physical growth, neurodevelopment, and behavior (2018) (44)
Hamster and Rat Pineal Gland β‐Adrenoceptor Characterization With Iodocyanopindolol and the Effect of Decreased Catecholamine Synthesis on the Receptor (1985) (44)
N-acetylserotonin suppresses hepatic microsomal membrane rigidity associated with lipid peroxidation. (2001) (44)
Influence of propranolol, phenoxybenzamine of phentolamine in the in vivo nocturnal rise of pineal melatonin levels in the Syrian hamster. (1981) (44)
Melatonin attenuates (‐)‐epigallocatehin‐3‐gallate‐triggered hepatotoxicity without compromising its downregulation of hepatic gluconeogenic and lipogenic genes in mice (2015) (44)
Circadian System Functionality, Hippocampal Oxidative Stress, and Spatial Memory in the APPswe/PS1dE9 Transgenic Model of Alzheimer Disease: Effects of Melatonin or Ramelteon (2012) (44)
Some perturbations that disturb the circadian melatonin rhythm. (1992) (44)
Absence of a nocturnal rise in either norepinephrine, N-acetyltransferase, hydroxyindole-O-methyltransferase or melatonin in the pineal gland of the domestic pig kept under natural environment photoperiods (1987) (44)
Suppression of oxygen toxicity by melatonin. (1998) (44)
Immunohistological localization of melatonin in the pineal gland and retina of the rat (1991) (44)
Hypochlorous acid-induced oxidative stress in Chinese hamster B14 cells: viability, DNA and protein damage and the protective action of melatonin. (2004) (44)
Melatonin reduces paraquat-induced genotoxicity in mice. (1998) (44)
Pineal Dependence of the Syrian Hamster's Nocturnal Serum Melatonin Surge (1986) (44)
Influence of light irradiance on hydroxyindole-O-methyltransferase activity, serotonin-N-acetyltranferase activity, and radioimmunoassayable melatonin levels in the pineal gland of the diurnally active Richardson's ground squirrel (1983) (44)
Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration (2016) (44)
Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress (2016) (44)
Memorial Symposium at Royal Society of Medicine, London, September 13 1997: Both melatonin and a putative nuclear melatonin receptor agonist CGP 52608 stimulate glutathione peroxidase and glutathione reductase activities in mouse brain in vivo (1997) (44)
Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state (2012) (44)
The emergence of melatonin in oncology: Focus on colorectal cancer (2019) (44)
Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections. (1986) (43)
Combination of melatonin and a peroxisome proliferator‐activated receptor‐γ agonist induces apoptosis in a breast cancer cell line (2009) (43)
Melatonin and renal protection: novel perspectives from animal experiments and human studies (review). (2014) (43)
Melatonin administration increases antioxidant enzymes activities and reduces lipid peroxidation in the rainbow trout (Oncorhynchus mykiss, Walbaum) erythrocytes (2009) (43)
Binding of 2-[125I]melatonin by rat thymus membranes during postnatal development. (1993) (43)
Respiratory distress syndrome in the newborn: role of oxidative stress (2001) (43)
Renal toxicity of the carcinogen δ-aminolevulinic acid: antioxidant effects of melatonin (2000) (43)
Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits (1990) (43)
Shift work and cancer: the evidence and the challenge. (2010) (43)
Pharmacological aspects of N‐acetyl‐5‐methoxytryptamine (melatonin) and 6‐methoxy‐ 1,2,3,4‐tetrahydro‐β‐carboline (pinoline) as antioxidants: Reduction of oxidative damage in brain region homogenates (1999) (42)
Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed (2020) (42)
Rapid-onset/offset, variably scheduled 60 Hz electric and magnetic field exposure reduces nocturnal serum melatonin concentration in nonhuman primates. (1995) (42)
Melatonin enhances astaxanthin accumulation in the green microalga Haematococcus pluvialis by mechanisms possibly related to abiotic stress tolerance (2018) (42)
The role of melatonin in the immuno-neuro-psychology of mental disorders. (2009) (42)
Photoperiod: Its importance as an impeller of pineal and seasonal reproductive rhythms (1980) (42)
Nature and the time course of seizures associated with surgical removal of the pineal gland from parathyroidectomized rats. (1973) (42)
Early photoperiodic conditions and pineal antigonadal function in male hamsters. (1970) (42)
Light/dark patterns of soluble vascular cell adhesion molecule‐1 in relation to melatonin in patients with ST‐segment elevation myocardial infarction (2007) (42)
Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis (2020) (42)
Melatonin Attenuates Estradiol-Induced Oxidative Damage to DNA: Relevance for Cancer Prevention (2001) (42)
The effects of thiourea, photoperiod and the pineal gland on the thyroid, adrenal and reproductive organs of female hamsters (1966) (42)
Melatonin has membrane receptor‐independent hypnotic action on neurons: an hypothesis (2011) (42)
Cardioprotection and pharmacological therapies in acute myocardial infarction: Challenges in the current era. (2014) (42)
The use of melatonin to combat mustard toxicity. REVIEW. (2008) (42)
Bromocriptine prevents the castration-induced rise in porphyrin concentration in the harderian glands of the male Syrian hamster, Mesocricetus auratus. (1989) (42)
Latitude, Vitamin D, Melatonin, and Gut Microbiota Act in Concert to Initiate Multiple Sclerosis: A New Mechanistic Pathway (2018) (42)
Oxidative Stress-Mediated Damage in Newborns with Necrotizing Enterocolitis: A Possible Role of Melatonin (2015) (42)
Electromagnetic fields and melatonin production. (1993) (42)
The pineal gland of the gerbil, Meriones unguiculatus (1979) (42)
Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo‐controlled, clinical trial (2014) (41)
Pineal research reviews (1983) (41)
Altered basal and postprandial plasma melatonin, gastrin, ghrelin, leptin and insulin in patients with liver cirrhosis and portal hypertension without and with oral administration of melatonin or tryptophan (2009) (41)
A Walnut-Enriched Diet Reduces the Growth of LNCaP Human Prostate Cancer Xenografts in Nude Mice (2013) (41)
Utilizing melatonin to combat bacterial infections and septic injury (2017) (41)
Role of melatonin in mucosal gastroprotection against aspirin‐induced gastric lesions in humans (2010) (41)
The Role of Light and Age in Determining Melatonin Production in the Pineal Gland (1983) (41)
Effects of melatonin on the nitric oxide treated retina (2004) (41)
Cardioprotective Role of Melatonin in Acute Myocardial Infarction (2020) (41)
Fetal/placental regulation of maternal melatonin in rats (2008) (41)
Inhibition of compensatory ovarian hypertrophy in the mouse and vole: a comparison of Altschule's pineal extract, pineal indoles, vasopressin, and oxytocin. (1972) (41)
Therapeutic Effect of Melatonin in Patients With Functional Dyspepsia (2007) (41)
Characterization of Pinealectomy Induced Convulsions in the Mongolian Gerbil (Meriones unguiculatus) (1978) (40)
Future of melatonin as a therapeutic agent. (2002) (40)
Melatonin delays cell proliferation by inducing G1 and G2/M phase arrest in a human osteoblastic cell line hFOB 1.19 (2010) (40)
Melatonin Protects Cultured Tobacco Cells against Lead-Induced Cell Death via Inhibition of Cytochrome c Translocation (2017) (40)
Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain. (1996) (40)
Genotoxicity of paraquat: micronuclei induced in bone marrow and peripheral blood are inhibited by melatonin. (2000) (39)
Relation of nocturnal melatonin levels to serum matrix metalloproteinase-9 concentrations in patients with myocardial infarction. (2007) (39)
Inhibitory effect of melatonin on diquat‐induced lipid peroxidation in vivo as assessed by the measurement of F2‐isoprostanes (2006) (39)
Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db mice (2011) (39)
The effects of melatonin supplementation on mental health, metabolic and genetic profiles in patients under methadone maintenance treatment (2018) (39)
Mitochondrial functions and melatonin: a tour of the reproductive cancers (2018) (39)
Novel bromomelatonin derivatives suppress osteoclastic activity and increase osteoblastic activity: implications for the treatment of bone diseases (2008) (39)
Melatonin as an endogenous regulator of diseases: The role of autophagy (2018) (39)
Hypothalamic cuts suggest a brain site for the antigonadotrophic action of melatonin in the syrian hamster (1981) (39)
Melatonin protects prepuberal testis from deleterious effects of bisphenol A or diethylhexyl phthalate by preserving H3K9 methylation (2018) (39)
Surgical removal of the olfactory bulbs increases sensitivity of the reproductive system of female rats to the inhibitory effects of late afternoon melatonin injections. (1980) (39)
The effects of pulsing magnetic fields on pineal melatonin synthesis in a teleost fish (brook trout, Salvelinus fontinalis) (1998) (39)
Transient hypertrophy of the ventral prostate and coagulating glands and accelerated thymic involution following pinealectomy in the mouse. (1971) (38)
Comparison of the Effects of β‐Adrenergic Agents on Pineal Serotonin N‐Acetyltransferase Activity and Melatonin Content in Two Species of Hamsters (1984) (38)
Daily and seasonal mitochondrial protection: Unraveling common possible mechanisms involving vitamin D and melatonin (2020) (38)
Melatonin reduces ventricular arrhythmias and preserves capillary perfusion during ischemia‐reperfusion events in cardiomyopathic hamsters (2007) (38)
High endogenous melatonin levels in critically ill children: a pilot study. (2013) (38)
Electric field exposure alters serum melatonin but not pineal melatonin synthesis in male rats. (1994) (38)
Functional diversity of the pineal hormone melatonin: its role as an antioxidant. (2009) (38)
Changes in pituitary prolactin levels of female hamsters as a function of age, photoperiod, and pinealectomy. (1975) (38)
Abnormal circadian rhythm of melatonin in Smith–Magenis syndrome patients with RAI1 point mutations (2011) (38)
Effect of long or short photoperiod on pineal melatonin content in the white-footed mouse, Peromyscus leucopus. (1981) (38)
Inverse correlation between “Synaptic” ribbon number and the density of adrenergic nerve endings in the pineal gland of various mammals (1983) (38)
New horizons of pineal research (1976) (38)
Seasonal reproduction in higher vertebrates (1980) (38)
Molecular and Cellular Mechanisms of Melatonin in Osteosarcoma (2019) (37)
Thyroxine 5'-deiodination in brown adipose tissue and pineal gland: implications for thermogenic regulation and role of melatonin. (1988) (37)
Protective effect of melatonin against homocysteine-induced vasoconstriction of human umbilical artery. (2000) (37)
Melatonin prevents the suppression of cardiac Ca(2+)-stimulated ATPase activity induced by alloxan. (1994) (37)
Effects of the pineal and melatonin on thyroid activity of male golden hamsters. (1979) (37)
The therapeutic role of long non‐coding RNAs in human diseases: A focus on the recent insights into autophagy (2019) (37)
Melatonin protects against lipid peroxidation and membrane rigidity in erythrocytes from patients undergoing cardiopulmonary bypass surgery (2003) (37)
Carcinogen-Induced, Free Radical-Mediated Reduction in Microsomal Membrane Fluidity: Reversal by Indole-3-propionic Acid (2001) (37)
Functional Interaction between Melatonin Signaling and Noncoding RNAs (2018) (37)
Endothelin-1 as a potential marker of melatonin's therapeutic effects in smoking-induced vasculopathy. (2010) (37)
The Role of MicroRNAs on Endoplasmic Reticulum Stress in Myocardial Ischemia and Cardiac Hypertrophy. (2019) (37)
Nocturnal secretion of melatonin in patients with upper digestive tract disorders. (2006) (37)
Effect of oxygen tension on the generation of alkanes and malondialdehyde by peroxidizing rat liver microsomes. (1987) (37)
Attempts to characterize the convulsive response of parathyroidectomized rats to pineal gland removal. (1972) (37)
Changes in Circadian Melatonin Synthesis in the Pineal Gland of Animals Exposed to Extremely Low Frequency Electromagnetic Radiation: A Summary of Observations and Speculation on Their Implications (1992) (36)
Melatonin attenuates osteosarcoma cell invasion by suppression of C‐C motif chemokine ligand 24 through inhibition of the c‐Jun N‐terminal kinase pathway (2018) (36)
Inhibition of 5'-deiodination of thyroxine suppresses the cold-induced increase in brown adipose tissue messenger ribonucleic acid for mitochondrial uncoupling protein without influencing lipoprotein lipase activity. (1990) (36)
Melatonin suppresses lung cancer metastasis by inhibition of epithelial-mesenchymal transition through targeting to Twist. (2019) (36)
Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension (2018) (36)
Melatonin: reproductive effects. (1978) (36)
Melatonin delivery in solid lipid nanoparticles: prevention of cyclosporine A induced cardiac damage (2009) (36)
Melatonin or l‐tryptophan accelerates healing of gastroduodenal ulcers in patients treated with omeprazole (2011) (36)
Free thyroxin index in normal, melatonin-treated and blind hamsters. (1977) (36)
Melatonin as a Potential Agent in the Treatment of Sarcopenia (2016) (36)
Inhibition of luteinizing hormone release and ovulation in PMS-treated rats by peripherally administered melatonin. (1971) (36)
Adrenal-mediated depression of N-acetyltransferase activity and melatonin levels in the rat pineal gland. (1986) (36)
Altered glial fibrillary acidic protein content and its degradation in the hippocampus, cortex and cerebellum of rats exposed to constant light: reversal by melatonin (2002) (35)
Exogenously administered and endogenously produced melatonin reduce hyperbaric oxygen-induced oxidative stress in rat lung. (2004) (35)
Pineal Gland: Influence on Gonads of Male Rats Treated with Androgen Three Days after Birth (1968) (35)
Oxidative damage to nuclear DNA: amelioration by melatonin. NEL Review. (1999) (35)
Pineal serotonin N-acetyltransferase activity and melatonin concentrations in prepubertal and adult Syrian hamsters exposed to short daily photoperiods. (1978) (35)
Pharmacological Studies on the Regulation of N‐Acetyltransferase Activity and Melatonin Content of the Pineal Gland of the Syrian Hamster (1985) (35)
Impact of Daylight Saving Time on circadian timing system: An expert statement. (2019) (35)
Inhibition of ERK1/2 Signaling Pathway is Involved in Melatonin's Antiproliferative Effect on Human MG-63 Osteosarcoma Cells (2016) (35)
Monitoring systemic oxidative stress in an animal model of amyotrophic lateral sclerosis (2011) (35)
Evaluation of enterochromaffin cells and melatonin secretion exponents in ulcerative colitis. (2013) (35)
Oral melatonin attenuates lung inflammation and airway hyperreactivity induced by inhalation of aerosolized pancreatic fluid in rats (2011) (35)
Red-light-induced suppression of melatonin synthesis is mediated by N-methyl-D-aspartate receptor activation in retinally normal and retinally degenerate rats. (1995) (35)
Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin (2016) (35)
The indoleamine melatonin as a free radical scavenger, electron donor, and antioxidant. In vitro and in vivo studies. (1996) (34)
The Pineal Gland and Its Hormones (1995) (34)
Refractoriness to the antigonadotrophic effects of melatonin in male hamsters and its interruption by exposure of the animals to long daily photoperiods. (1979) (34)
Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review. (2016) (34)
Delayed puberty in blinded anosmic female rats: role of the pineal gland. (1970) (34)
Melatonin's inhibitory effect on growth of ME-180 human cervical cancer cells is not related to intracellular glutathione concentrations. (1995) (34)
Prevention of ERK activation involves melatonin‐induced G1 and G2/M phase arrest in the human osteoblastic cell line hFOB 1.19 (2012) (34)
In vivo responses of the pineal gland of the Syrian hamster to isoproterenol or norepinephrine. (1982) (34)
RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line. (2004) (34)
Fine structural features of adrenergic nerve fibers and endings in the pineal gland of the rat, ground squirrel and chinchilla. (1977) (34)
Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates. (2002) (34)
Effects of photoperiod on hamster pineal melatonin concentrations (1980) (34)
Melatonin and pancreatic cancer: Current knowledge and future perspectives (2018) (33)
Beneficial effects of melatonin on nicotine‐induced vasculopathy (2010) (33)
The pineal gland signals autumn to reindeer (Rangifer tarandus tarandus) exposed to the continuous daylight of the Arctic summer (1994) (33)
Effect of photoperiod and melatonin on testicular development in the white-footed mouse, Peromyscus leucopus. (1980) (33)
Changes in lipid peroxidation during pregnancy and after delivery in rats: effect of pinealectomy. (2000) (33)
Potential use of melatonin in skin cancer treatment: A review of current biological evidence (2019) (33)
Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms (2020) (33)
Characterization and measurement of [125I]iodopindolol binding in individual rat pineal glands: existence of a 24-h rhythm in β-adrenergic receptor density (1988) (33)
A method for measurement of prolactin in the hamster by means of radioimmunoassay. (1973) (33)
Pineal N-acetyltransferase activity in blinded and anosmic male rats. (1971) (33)
Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation (2018) (33)
Melatonin and non-small cell lung cancer: new insights into signaling pathways (2019) (33)
5α-Dihydrotestosterone Administration Converts Indolamine Metabolism and Porphyrin Content of the Female Syrian Hamster Harderian Gland to the Male Type (1989) (33)
Melatonin prevents cadmium‐induced bone damage: First evidence on an improved osteogenic/adipogenic differentiation balance of mesenchymal stem cells as underlying mechanism (2019) (32)
Role of oxidative stress in neonatal respiratory distress syndrome. (2019) (32)
Melatonin synthesis: multiplicity of regulation. (1991) (32)
Melatonin is a potential inhibitor of ovarian cancer: molecular aspects (2019) (32)
Melatonin inhibits seed germination by crosstalk with abscisic acid, gibberellin, and auxin in Arabidopsis (2021) (32)
Melatonin: does it have utility in the treatment of haematological neoplasms? (2018) (32)
Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor L‐tryptophan in rats (2008) (32)
The Pineal and Its Indole Products: Basic Aspects and Clinical Applications (1989) (32)
Antioxidant and Pro-Oxidant Activities of Melatonin in the Presence of Copper and Polyphenols In Vitro and In Vivo (2019) (32)
Morphofunctional aspects of the mammalian pineal gland (1992) (32)
In vivo hepatic oxidative stress because of carbon tetrachloride toxicity: protection by melatonin and pinoline (2010) (32)
Circadian variations of adrenergic receptors in the mammalian pineal gland: A review (2005) (32)
The Syrian hamster pineal gland responds to isoproterenol in vivo at night. (1987) (32)
The effect of subcutaneous injections of melatonin, arginine vasotocin, and related peptides on pituitary and plasma levels of luteinizing hormone, follicle-stimulating hormone, and prolactin in castrated adult male rats. (1979) (32)
Acute and delayed sulfur mustard toxicity; novel mechanisms and future studies (2008) (32)
Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens (2020) (32)
Muscular spasms and death in thyroparathyroidectomized rats subjected to pinealectomy. (1972) (31)
Melatonin and its metabolites as chemical agents capable of directly repairing oxidized DNA (2019) (31)
Effects of blinding, pinealectomy and superior cervical ganglionectomy on free thyroxine index of male golden hamsters. (1977) (31)
Apoptosis in primary lymphoid organs with aging (2003) (31)
Melatonin Protects the Heart against both Ischemia/Reperfusion Injury and Chemotherapeutic Drugs (2004) (31)
The role of melatonin in targeting cell signaling pathways in neurodegeneration (2019) (31)
Melatonin is associated with reverse remodeling after cardiac resynchronization therapy in patients with heart failure and ventricular dyssynchrony. (2016) (31)
Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment (2020) (31)
The potential usefulness of serum melatonin level to predict heart failure in patients with hypertensive cardiomyopathy. (2014) (31)
Melatonin versus midazolam premedication in children undergoing surgery: A pilot study (2016) (31)
Exogenous melatonin improves cotton (Gossypium hirsutum L.) pollen fertility under drought by regulating carbohydrate metabolism in male tissues. (2020) (31)
Regularly scheduled, day-time, slow-onset 60 Hz electric and magnetic field exposure does not depress serum melatonin concentration in nonhuman primates. (1995) (31)
Melatonin in the biliary tract and liver: health implications. (2014) (31)
Melatonin: a universal time messenger. (2015) (30)
Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-β: A Protective Role of Melatonin (2012) (30)
Melatonin and ubiquitin: what’s the connection? (2014) (30)
Melatonin inhibits Benzo(a)pyrene-Induced apoptosis through activation of the Mir-34a/Sirt1/autophagy pathway in mouse liver. (2020) (30)
Age-associated reduction in pineal beta-adrenergic receptor density is prevented by life-long food restriction in rats. (1992) (30)
No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial. (2010) (30)
Pineal modulation of the rat caudate‐putamen spontaneous neuronal activity: Roles of melatonin and vasotocin (1993) (30)
Melatonin reduces protein and lipid oxidative damage induced by homocysteine in rat brain homogenates (2007) (30)
Effects of miR-34b/miR-892a Upregulation and Inhibition of ABCB1/ABCB4 on Melatonin-Induced Apoptosis in VCR-Resistant Oral Cancer Cells (2020) (30)
Pineal, neural and photic control of reproductive organ size in early androgen-treated male rats. (1968) (30)
Retinal lipid peroxidation in vitro is inhibited by melatonin (1995) (30)
Evidence that interferon-gamma alters pineal metabolism both indirectly via sympathetic nerves and directly on the pinealocytes. (1991) (30)
Melatonin prevents apoptosis and enhances HSP27 mRNA expression induced by heat shock in HL‐60 cells: possible involvement of the MT2 receptor (2003) (30)
Tryptophan administration inhibits nocturnal N-acetyltransferase activity and melatonin content in the rat pineal gland. Evidence that serotonin modulates melatonin production via a receptor-mediated mechanism. (1990) (30)
Effect of exogenous melatonin on viability, ingestion capacity, and free-radical scavenging in heterophils from young and old ringdoves (Streptopelia risoria) (2007) (30)
A Simple, Rapid Method for Determination of Melatonin in Plant Tissues by UPLC Coupled with High Resolution Orbitrap Mass Spectrometry (2017) (29)
Characterization of serotonin and N‐acetylserotonin systems in the human epidermis and skin cells (2019) (29)
The Effects of Melatonin Supplementation on Parameters of Mental Health, Glycemic Control, Markers of Cardiometabolic Risk, and Oxidative Stress in Diabetic Hemodialysis Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. (2020) (29)
Antioxidant effects of melatonin in rats during chronic exposure to hyperbaric oxygen (2007) (29)
Age-associated changes in pineal serotonin N-acetyltransferase activity and melatonin content in the male gerbil. (1981) (29)
Identification of oxidative stress–related Xdh gene as a di(2‐ethylhexyl)phthalate (DEHP) target and the use of melatonin to alleviate the DEHP‐induced impairments in newborn mouse ovaries (2019) (29)
Establishing the Use of Melatonin as an Adjuvant Therapeutic Against Paraquat-Induced Lung Toxicity in Rats (2008) (29)
Porphyrin levels in the Harderian glands of female and male Syrian hamsters: Early changes following either gonadectomy or light deprivation and lack of a circadian rhythm (1989) (29)
Effects of blinding or afternoon melatonin injections on plasma cholesterol, triglycerides, glucose, TSH and thyroid hormone levels in male and female Syrian hamsters. (1982) (29)
MELATONIN: POTENTIAL UTILITY FOR IMPROVING PUBLIC HEALTH (2006) (29)
Potential benefits of melatonin in organ transplantation: a review. (2016) (29)
Melatonin therapy of pediatric sleep disorders: Recent advances, why it works, who are the candidates and how to treat (2007) (29)
Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT‐1 melanoma cells (2019) (29)
Breast cancer cells: Modulation by melatonin and the ubiquitin-proteasome system – A review (2015) (29)
Simultaneous Determination of N-Acetyltransferase Activity, Hydroxyindole-O-methyl-transferase Activity, and Melatonin Content in the Pineal Gland of the Syrian Hamster (1984) (29)
Use of Melatonin in Oxidative Stress Related Neonatal Diseases (2020) (29)
Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells (2018) (29)
Glioblastoma: Role of Mitochondria N-acetylserotonin/Melatonin Ratio in Mediating Effects of miR-451 and Aryl Hydrocarbon Receptor and in Coordinating Wider Biochemical Changes (2019) (29)
Inhibition of SERPINA3N‐dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride–induced neurotoxicity (2019) (29)
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases (2021) (29)
The effects of melatonin supplementation on inflammatory markers among patients with metabolic syndrome or related disorders: a systematic review and meta-analysis of randomized controlled trials (2018) (28)
Melatonin Pharmacological Blood Levels Increase Total Antioxidant Capacity in Critically Ill Patients (2017) (28)
Breastfeeding and the gut-brain axis: is there a role for melatonin? (2017) (28)
Comparative effects of continual lighting and pinealectomy on the eyes, the Harderian glands and reproduction in pigmented and albino rats. (1973) (28)
Melatonin treatment protects against spinal cord injury induced functional and biochemical changes in rat urinary bladder (2012) (28)
Inhibition of human chorionic gonadotrophin-induced hypertrophy of the ovaries and uterus in immature mice by some pineal indoles, 6-hydroxymelatonin and arginine vasotocin. (1976) (28)
Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis (2021) (28)
Prognostic value of nocturnal melatonin levels as a novel marker in patients with ST-segment elevation myocardial infarction. (2006) (28)
Pineal melatonin content in photoperiodically responsive and non-responsive phenotypes of deer mice. (1988) (28)
Pineal and thyroid functions in newborn seals. (1995) (28)
Evidence of melatonin ameliorative effects on the blood-testis barrier and sperm quality alterations induced by cadmium in the rat testis. (2021) (28)
HYPOTROPHIC REPRODUCTIVE ORGANS AND NORMAL GROWTH IN MALE RATS TREATED WITH MELATONIN (1971) (28)
Melatonin counteracts alterations in oxidative metabolism and cell viability induced by intracellular calcium overload in human leucocytes: changes with age. (2010) (28)
Reduction in pineal N-acetyltransferase activity and pineal and serum melatonin levels in rats after their exposure to red light at night (1993) (28)
A Computer-Assisted Systematic Search for Melatonin Derivatives with High Potential as Antioxidants (2018) (28)
Tryptophan increases nocturnal rest and affects melatonin and serotonin serum levels in old ringdove (2007) (28)
Depressed pituitary prolactin levels in blinded anosmic female rats: rôle of the pineal gland. (1972) (28)
A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells (2015) (28)
Pineal and associated neuroendocrine rhythms (1976) (27)
Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia (2009) (27)
Endocrine rhythms associated with pineal gland function. (1975) (27)
Effect of isoproterenol and dibutyryl cyclic AMP on thyroxine type-II 5′-deiodinase and N-acetyltransferase activities in rat pineal organ cultures (1988) (27)
mtDNA T8993G mutation‐induced mitochondrial complex V inhibition augments cardiolipin‐dependent alterations in mitochondrial dynamics during oxidative, Ca2+, and lipid insults in NARP cybrids: a potential therapeutic target for melatonin (2012) (27)
Influence of Protein-Calorie Malnutrition on the Circadian Rhythm of Pineal Melatonin in the Rat (1981) (27)
Diurnal variation in the serotonin content and turnover in the pineal gland of the syrian hamster (1983) (27)
Role of the pineal gland in growth restraint of adult male rats by light and smell deprivation. (1971) (27)
Studies on the minimal dosage of melatonin required to inhibit pineal antigonadotrophic activity in male golden hamsters. (1975) (27)
Melatonin improves deferoxamine antioxidant activity in protecting against lipid peroxidation caused by hydrogen peroxide in rat brain homogenates (2002) (27)
Regulation of rat pineal melatonin synthesis: Effect of monoamine oxidase inhibition (1982) (27)
Melatonin specifically stimulates type-II thyroxine 5'-deiodination in brown adipose tissue of Syrian hamsters. (1989) (27)
Changes in Indole Metabolism in Organ Cultured Rat Pineal Glands Induced by Interferon‐γ (1990) (27)
Day-Night Differences in the Response of the Pineal Gland to Swimming Stress 1 (1988) (27)
Effect of ovariectomy and constant dark on the weight of reproductive and certain other organs in the female vole, Microtus montanus. (1973) (27)
Comparative Study of the Activity/Rest Rhythms in Young and Old Ringdove (Streptopelia Risoria): Correlation with Serum Levels of Melatonin and Serotonin (2006) (27)
δ‐Aminolevulinic acid‐induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: An in vitro and in vivo study (1998) (27)
Tryptophan modulates cell viability, phagocytosis and oxidative metabolism in old ringdoves. (2007) (26)
Melatonin and pinoline prevent aluminium-induced lipid peroxidation in rat synaptosomes. (2003) (26)
Pineal gland: evidence for an influence on ethanol preference in male Syrian hamsters. (1974) (26)
Adrenalectomy Prevents Changes in Rat Pineal Melatonin Content N‐Acetyltransferase Activity Induced by Acute Insulin Stress (1987) (26)
Does maximal serotonin N-acetyltransferase activity necessarily reflect maximal melatonin production in the rat pineal gland? (1984) (26)
Attenuation of ultraviolet A‐induced alterations in NIH3T3 dermal fibroblasts by melatonin (2014) (26)
Inhibition of Pineal Type‐II 5′‐Deiodinase Does Not Affect the Nocturnal Increase of N‐Acetyltransferase Activity and Melatonin Content in Either Euthyroid or Thyroidectomized Rats (1988) (26)
Reduced pineal and plasma melatonin levels and gonadal atrophy in old hamsters kept under winter photoperiods (1982) (26)
Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil. (1998) (26)
In situ demonstration of improvement of liver mitochondria function by melatonin after cold ischemia. (2006) (26)
A counter antigonadotrophic effect of melatonin in male rats. (1975) (26)
Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin. (2008) (26)
Interferon-gamma modulates melatonin production in rat pineal glands in organ culture. (1990) (26)
The pineal gland of the blind-anosmic female rat: its influence on medial basal hypothalamic lrh, pif and/or prf activity in vivo. (1975) (26)
N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects. (2015) (26)
Pituitary and plasma LH and prolactin levels in female rats rendered blind and anosmic: influence of the pineal gland. (1975) (26)
Light pollution, melatonin suppression and cancer growth (2006) (26)
Flavonoids inhibit both rice and sheep serotonin N‐acetyltransferases and reduce melatonin levels in plants (2018) (26)
Chronic exposure to short photoperiod inhibits free thyroxine index and plasma levels of TSH, T4, triiodothyronine (T3) and cholesterol in female Syrian hamsters. (1982) (26)
Melatonin biosynthesis enzymes recruit WRKY transcription factors to regulate melatonin accumulation and transcriptional activity on W‐box in cassava (2018) (26)
The potential use of melatonin to treat protozoan parasitic infections: A review. (2017) (26)
Antioxidative Capacity of Melatonin (2001) (26)
Elevated pituitary LH and depressed pituitary prolactin levels in female hamsters with pineal-induced gonadal atrophy and the effects of chronic treatment with synthetic LRF. (1974) (26)
Pineal-induced alteration of estrous cycles in blinded hamsters. (1970) (25)
Hamster pineal noradrenaline: levels over a regulated lighting period and the influence of superior cervical ganglionectomy. (1976) (25)
The depression in rat pineal melatonin production after saline injection at night may be elicited by corticosterone (1988) (25)
A meta‐analysis of microRNA networks regulated by melatonin in cancer: Portrait of potential candidates for breast cancer treatment (2020) (25)
Melatonin suppresses autoxidation and hydrogen peroxide-induced lipid peroxidation in monkey brain homogenate. (2000) (25)
The effect of resveratrol on neurodegenerative disorders: possible protective actions against autophagy, apoptosis, inflammation and oxidative stress. (2019) (25)
Inhibition of growth of gonadal dependent structures by arginine vasotocin and purified bovine pineal fractions in immature mice and hamsters. (1974) (25)
Perspectives on the use of melatonin to reduce cytotoxic and genotoxic effects of methacrylate‐based dental materials (2011) (25)
Pineal influence on intermale aggression in adult house mice (1975) (25)
The combination of twice daily luteinizing hormone-releasing factor administration and renal pituitary homografts restores normal reproductive organ size in male hamsters with pineal-mediated gonadal atrophy. (1980) (25)
Melatonin actions in the heart; more than a hormone (2018) (25)
Effects of injections and/or chronic implants of melatonin and 5-methoxytryptamine on plasma thyroid hormones in male and female Syrian hamsters. (1984) (25)
Hypophysectomy prevents the castration-induced increase in porphyrin concentrations in the harderian glands of the male golden hamster: a possible role for prolactin. (1992) (25)
Influence of melatonin, 5-methoxytryptophol and pinealectomy on pituitary and plasma gonadotropin and prolactin levels in castrated adult male rats. (1973) (25)
The Mammalian Pineal Gland as an End Organ of the Visual System11Work by the author was supported by grants from the National Science Foundation and from the National Institutes of Health. (1993) (25)
Levels of membrane fluidity in the spinal cord and the brain in an animal model of amyotrophic lateral sclerosis (2011) (25)
Melatonin as a potential inhibitory agent in head and neck cancer (2017) (25)
Unusual responses of nocturnal pineal melatonin synthesis and secretion to swimming: Attempts to define mechanisms (1993) (25)
Overexpression of melatonin membrane receptors increases calcium‐binding proteins and protects VSC4.1 motoneurons from glutamate toxicity through multiple mechanisms (2013) (25)
Orally administered melatonin improves nocturnal rest in young and old ringdoves (Streptopelia risoria). (2007) (25)
The Effects of Melatonin Supplementation on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2018) (25)
Melatonin reduces neuronal loss and cytoskeletal deterioration: implications for Psychiatry (2013) (25)
Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin? (2020) (25)
Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing (2020) (24)
Pineal—Reproductive Interactions (1985) (24)
Pineal regulation of growth hormone synthesis and release in blinded and blinded-anosmic male rats. (1971) (24)
A possible relationship between the pineal gland and ethanol preference in the rat. (1973) (24)
Autoxidation and toxicant-induced oxidation of lipid and DNA in monkey liver: reduction of molecular damage by melatonin. (2001) (24)
Pineal regulation of immunoreactive luteinizing hormone and prolactin in light-deprived female hamsters. (1974) (24)
Pan‐cancer genomic analyses reveal prognostic and immunogenic features of the tumor melatonergic microenvironment across 14 solid cancer types (2019) (24)
Melatonin promotes metabolism of bisphenol A by enhancing glutathione-dependent detoxification in Solanum lycopersicum L. (2019) (24)
Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells (2018) (24)
Melatonin prevents oxidative damage to protein and lipid induced by ascorbate-Fe(3+)-EDTA: Comparison with glutathione and alpha-tocopherol. (2000) (24)
Interaction of photic and olfactory stimuli in mediating pineal-induced gonadal regression in adult female rats. (1970) (24)
Melatonin and tadalafil treatment improves erectile dysfunction after spinal cord injury in rats (2014) (24)
Elevated daytime rat pineal and serum melatonin levels induced by isoproterenol are depressed by swimming. (1987) (24)
Beneficial neurobiological effects of melatonin under conditions of increased oxidative stress (2002) (24)
Effects of melatonin and natural and synthetic analogues of arginine vasotocin on plasma prolactin levels in adult male rats. (1978) (24)
2-Nitropropane-induced lipid peroxidation: antitoxic effects of melatonin. (1998) (24)
SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin (2021) (23)
Modification of testicular and thyroid function by chronic exposure to short photoperiod: a comparison in four rodent species. (1984) (23)
Androgenic control of immunoreactive somatostatin in the Harderian gland of the Syrian hamster. (1988) (23)
The midline pineal “eye”: MR and CT characteristics of the pineal gland with and without benign cyst formation (1995) (23)
Historical Perspective and Evaluation of the Mechanisms by which Melatonin Mediates Seasonal Reproduction in Mammals (2018) (23)
The pineal complex and its relationship to other epithalamic structures. (1977) (23)
Long‐term Aβ exposure augments mCa2+‐independent mROS‐mediated depletion of cardiolipin for the shift of a lethal transient mitochondrial permeability transition to its permanent mode in NARP cybrids: a protective targeting of melatonin (2012) (23)
Effects of Photoperiod or Exogenous Melatonin Administration on the Activity of N‐Acetyltransferase and Hydroxyindole‐O‐Methyltransferase and the Melatonin Content of the Harderian Gland of Two Strains of Female Syrian Hamsters (1988) (23)
Melatonin and tryptophan counteract lipid peroxidation and modulate superoxide dismutase activity in ringdove heterophils in vivo. Effect of antigen-induced activation and age (2009) (23)
Nocturnal Increase of Type II Thyroxine 5′-Deiodinase Activity in the Syrian Hamster Harderian Gland is Abolished by Light Exposure and Induced by Isoproterenol 1 (1989) (23)
Identification of a novel melatonin‐binding nuclear receptor: Vitamin D receptor (2019) (23)
Androgenic control of N‐acetyltransferase activity in the harderian glands of the syrian hamster is mediated by 5α‐dihydrotestosterone (1990) (23)
Heme precursor 5‐aminolevulinic acid alters brain tryptophan and serotonin levels without changing pineal serotonin and melatonin concentrations (1989) (23)
Central and peripheral neural pathways necessary for pineal function in the adult female rat. (1971) (23)
5‐methoxytryptophol preserves hepatic microsomal membrane fluidity during oxidative stress (2000) (23)
Melatonin secretion and metabolism in patients with hepatic encephalopathy (2013) (23)
Pineal Melatonin Production: Endocrine and Age Effects1 (1982) (22)
Day/night differences in stress‐induced gastric lesions in rats with an intact pineal gland or after pinealectomy (2008) (22)
Global climate change and invariable photoperiods: A mismatch that jeopardizes animal fitness (2019) (22)
Radioautographic study of cellular replacement in the adrenal cortex of male rats. (1966) (22)
Melatonin : your body's natural wonder drug (1995) (22)
Role of Postsynaptic α‐Adrenergic Receptors in the β ‐Adrenergic Stimulation of Melatonin Production in the Syrian Hamster Pineal Gland in Organ Culture (1989) (22)
Pineal melatonin: circadian rhythm and variations during the hibernation cycle in the ground squirrel, Spermophilus lateralis. (1986) (22)
Plasticity of glucose metabolism in activated immune cells: advantages for melatonin inhibition of COVID-19 disease (2020) (22)
The role of melatonin in parasite biology. (2012) (22)
The pineal-1977 (1977) (22)
The key role of the sequential proton loss electron transfer mechanism on the free radical scavenging activity of some melatonin-related compounds (2016) (22)
Melatonin as an Antitumor Agent against Liver Cancer: An Updated Systematic Review (2021) (21)
Melatonin prevents δ-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+ (2001) (21)
Melatonin and morphine: potential beneficial effects of co‐use (2020) (21)
Immune‐pineal axis protects rat lungs exposed to polluted air (2020) (21)
Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats (2020) (21)
Differential effects of the pineal gland on LH-RH and FSH-RH activity in the medial basal hypothalamus of the male golden hamster. (1979) (21)
Melatonin synthesis in the retina and pineal gland of djungarian hamsters at different times of the year (1995) (21)
Melatonin supplementation restores cellular proliferation and DNA synthesis in the splenic and thymic lymphocytes of old rats. (2003) (21)
Melatonin in the context of the reported bioeffects of environmental electromagnetic fields (1998) (21)
Melanopsin System Dysfunction in Smith-Magenis Syndrome Patients. (2018) (21)
First evidence of the protective role of melatonin in counteracting cadmium toxicity in the rat ovary via the mTOR pathway. (2020) (21)
Gender differences and time course of castration-induced changes in porphyrins, indoles, and proteins in the Harderian glands of the Syrian hamster. (1991) (21)
Pineal-mediated regression of the reproductive organs of female hamsters exposed to natural photoperiods during the winter months. (1974) (21)
N-acetyltransferase activity and indole contents of the male Syrian hamster Harderian gland: changes during the light:dark cycle. (1989) (21)
Influence of a skeleton photoperiod on reproductive organ atrophy in the male golden hamster. (1980) (21)
NOCTURNAL DECREASES IN NITRIC OXIDE AND CYCLIC GMP CONTENTS IN THE CHICK BRAIN AND THEIR PREVENTION BY LIGHT (1996) (21)
Prevention by melatonin of short day induced atrophy of the reproductive systems of male and female hamsters. (1977) (20)
The effects of melatonin administration on disease severity and sleep quality in children with atopic dermatitis: A randomized, double‐blinded, placebo‐controlled trial (2018) (20)
Effects of Photoperiod and Subcutaneous Melatonin Implants on the Reproductive Status of Adult White‐footed Mice (Peromyscus leucopus) (1981) (20)
Endocrine and metabolic effects of life-long food restriction in rats. (1991) (20)
The dual roles of melatonin biosynthesis enzymes in the coordination of melatonin biosynthesis and autophagy in cassava (2020) (20)
Melatonin: A Potential Agent in Delaying Leaf Senescence (2021) (20)
Prolactin-releasing activity of arginine vasotocin in vitro. (1975) (20)
Regulation of cancer cell glucose metabolism is determinant for cancer cell fate after melatonin administration (2020) (20)
Quantitative changes in the numbers of dense-core vesicles and 'synaptic' ribbons in pinealocytes of the Djungarian hamster (Phodopus sungorus) following sympathectomy. (1982) (20)
Reported biological consequences related to the suppression of melatonin by electric and magnetic field exposure (1995) (20)
Effect of melatonin and tryptophan on humoral immunity in young and old ringdoves (Streptopelia risoria) (2009) (20)
Effect of the pineal gland on alcohol consumption by congenitally blind male rats. (1973) (20)
Effects of short-term cold exposure on pineal biosynthetic function in rats. (1988) (20)
Changes in serotonin levels, N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the pineal gland of the Richardson's ground squirrel in relation to the light-dark cycle. (1984) (20)
Exosomes and Melatonin: Where Their Destinies Intersect (2021) (20)
A study of indoles which inhibit pineal antigonadotrophic activity in male hamsters. (1975) (20)
Effect of melatonin on cell growth, metabolic activity, and cell cycle distribution (2001) (20)
Pulsed static magnetic field effects on in-vitro pineal indoleamine metabolism. (1992) (20)
Electromagnetic Fields and Circadian Rhythmicity (1992) (20)
Obesity-associated alterations in cardiac connexin-43 and PKC signaling are attenuated by melatonin and omega-3 fatty acids in female rats (2018) (20)
Reproductive effects of 6-chloromelatonin implants and/or injections in male and female Syrian hamsters (Mesocricetus auratus). (1986) (20)
Opioid and dopamine involvement in prolactin release induced by arginine vasotocin and vasopressin in the male rat. (1984) (20)
Clock genes and the role of melatonin in cancer cells: an overview (2019) (20)
Effect of superior cervical ganglionectomy on the ultrastructure of the pinealocyte in the cotton rat (Sigmodon hispidus). (1983) (20)
Melatonin: Helping cells cope with oxidative disaster (2010) (20)
Pineal Melatonin Content throughout the Hamster Estrous Cycle 1 (1979) (20)
Tryptophan administration in rats enhances phagocytic function and reduces oxidative metabolism. (2008) (20)
Closed head injury increases extracellular levels of antioxidants in rat hippocampus in vivo: an adaptive mechanism? (2001) (20)
Influence of morning melatonin injections on the antigonadotrophic effects of afternoon melatonin administration in male and female hamsters. (1981) (19)
Identification of 11-cis-retinal and demonstration of its light-induced isomerization in the chicken pineal gland (1991) (19)
Circadian disruption, melatonin rhythm perturbations and their contributions to chaotic physiology. (2020) (19)
Melatonin Concentration in the Cerebral Vascular Sinuses of Sheep and Evidence for Its Episodic Release (1988) (19)
Renal toxicity of the carcinogen delta-aminolevulinic acid: antioxidant effects of melatonin. (2000) (19)
Regulation of Melatonin in the Harderian Glands of Golden Hamsters (1989) (19)
Melatonin, vitamin E, and estrogen reduce damage induced by kainic acid in the hippocampus: potassium‐stimulated GABA release (2001) (19)
Melatonin Reduces 3H-Nitrendipine Binding in the Heart (1994) (19)
Protective Role of Melatonin and Its Metabolites in Skin Aging (2022) (19)
Arginine vasotocin: structure-activity relationships and influence on gonadal growth and function. (1976) (19)
New proposal involving nanoformulated melatonin targeted to the mitochondria as a potential COVID-19 treatment (2020) (19)
Dose-dependent prolactin releasing activity of arginine vasotocin in intact and pinealectomized estrogen-progesterone treated adult male rats. (1976) (19)
Melatonin Secretion Is Increased in Children with Severe Traumatic Brain Injury (2017) (19)
ACTION OF SUBCUTANEOUS IMPLANTS OR INJECTIONS OF MELATONIN ON REPRODUCTIVE AND METABOLIC VARIABLES AND PINEAL CONCRETIONS IN MALE GERBILS (MERIONES UNGUICULAT US) (1983) (19)
Sirtuins and the circadian clock interplay in cardioprotection: focus on sirtuin 1 (2021) (19)
Pineal control of reproduction. (1981) (18)
Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis (2021) (18)
When the Circadian Clock Becomes a Ticking Time Bomb (2012) (18)
Melatonin counteracts potentiation by homocysteine of KCL-induced vasoconstriction in human umbilical artery: relation to calcium influx. (2001) (18)
Melatonin suppresses homocysteine enhancement of serotonin‐induced vasoconstriction in the human umbilical artery (2001) (18)
The pineal melatonin rhythm and its regulation by light in a subterranean rodent, the valley pocket gopher (Thomomys bottae) (1994) (18)
Melatonin protection from chronic, low-level ionizing radiation. (2012) (18)
Urinary 6-sulfatoxymelatonin excretion in humans during domestic exposure to 50 hertz electromagnetic fields. (2005) (18)
Melatonin, a calpain inhibitor in the central nervous system: Current status and future perspectives (2018) (18)
Single Administration of Melatonin Modulates the Nitroxidergic System at the Peripheral Level and Reduces Thermal Nociceptive Hypersensitivity in Neuropathic Rats (2017) (18)
Thyroxine 5'-deiodinase activity in brown adipose tissue, Harderian gland, pineal gland and pituitary gland of the male Syrian hamster (Mesocricetus auratus) (1988) (18)
Iodothyronine 5'-deiodinating activity in the pineal gland. (1992) (18)
The influence of artificial and natural short photoperiods on male syrian hamsters: Reproductive effects (1984) (18)
Melatonin synthesis in and uptake by mitochondria: implications for diseased cells with dysfunctional mitochondria. (2021) (18)
New insights into antimetastatic signaling pathways of melatonin in skeletomuscular sarcoma of childhood and adolescence (2020) (18)
An Examination of the Putative Role of Melatonin in Exosome Biogenesis (2021) (18)
Superior cervical ganglionectomy results in the loss of pineal concretions in the adult male gerbil (meriones unguiculatus) (1985) (18)
Failure of the pineal gland to prevent gonadotrophin-induced ovarian stimulation in blinded hamsters. (1967) (18)
Melatonin, a toll‐like receptor inhibitor: Current status and future perspectives (2018) (18)
Oral administration of melatonin to old ring doves (Streptopelia risoria) increases plasma levels of melatonin and heterophil phagocytic activity. (2005) (18)
Elevated ambient temperature retards the atrophic response of the neuroendocrine-reproductive axis of male Syrian hamsters to either daily afternoon melatonin injections or to short photoperiod exposure. (1987) (18)
The pineal gland and seasonal reproductive adjustments (1975) (18)
Twenty‐four hour urinary excretion of 6‐hydroxymelatonin sulfate in Down syndrome subjects (1996) (18)
Insulin-like Growth Factor-1 in Syrian Hamsters: Interactions of Photoperiod, Gonadal Steroids, Pinealectomy, and Continuous Melatonin Treatment (1994) (18)
Serum melatonin after a single aqueous subcutaneous injection in Syrian hamsters. (1986) (18)
Switching diseased cells from cytosolic aerobic glycolysis to mitochondrial oxidative phosphorylation: A metabolic rhythm regulated by melatonin? (2020) (18)
Melatonin and cardiac pathophysiology (2009) (17)
Melatonin protects against taurolithocholic‐induced oxidative stress in rat liver (2010) (17)
Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer (2021) (17)
Pineal indoleamine metabolism in the cotton rat, Sigmodon hispidus: studies on norepinephrine, serotonin, N-acetyltransferase activity and melatonin. (1982) (17)
Melatonin induction of testicular recrudescence in hamsters and its subsequent inhibitory action on the antigonadotrophic influence of darkness on the pituitary-gonadal axis. (1976) (17)
Melatonin and cardioprotection in the acute myocardial infarction: a promising cardioprotective agent. (2012) (17)
Non-suppressibility by room light of pineal N-acetyltransferase activity and melatonin levels in two diurnally active rodents, the Mexican ground squirrel (Spermophilus mexicanus) and the eastern chipmunk (Tamias striatus). (1984) (17)
The Pineal Gland: An Important Link to the Environment (1986) (17)
Control of secretory lipid droplets in the harderian gland by testosterone and the photoperiod: comparison of two species of hamsters. (1995) (17)
Secretion of melatonin and 6-sulfatoxymelatonin urinary excretion in functional dyspepsia. (2011) (17)
Mechanism of melatonin protection against copper‐ascorbate‐induced oxidative damage in vitro through isothermal titration calorimetry (2017) (17)
Hormonal modulation of cyclic melatonin production in the pineal gland of rats and Syrian hamsters: effects of thyroidectomy or thyroxine implant. (1985) (17)
Photoperiod, Pineal and Reproduction in Mammals Including Man (1987) (17)
Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer (2019) (17)
The influence of different light irradiances on pineal N-acetyltransferase activity and melatonin levels in the cotton rat, Sigmodon hispidus. (1983) (17)
Melatonin Ameliorates Inflammation and Oxidative Stress by Suppressing the p38MAPK Signaling Pathway in LPS-Induced Sheep Orchitis (2020) (17)
Day:night variations of melatonin, 5-hydroxyindole acetic acid, serotonin, serotonin N-acetyltransferase, tryptophan, norepinephrine and dopamine in the rabbit pineal gland. (1984) (17)
Pharmacokinetics of Melatonin: The Missing Link in Clinical Efficacy? (2016) (17)
Involvement of Calcium in Pineal Gland Function (1991) (17)
Harderian gland N-acetyltransferase activity in the male Syrian hamster: effects of gonadectomy, short photoperiod exposure, or subcutaneous melatonin implants. (1988) (17)
Interaction of daily injections and subcutaneous reservoirs of melatonin on the reproductive physiology of female Syrian hamsters. (1979) (17)
Effects of advancing age on the ultrastructure of pinealocytes in the male white-footed mouse (Peromyscus leucopus). (1982) (17)
Melatonin in fish: Circadian rhythm and functions (2010) (17)
Involvement of alpha- and beta-adrenergic receptors in the regulation of rat pineal N-acetyltransferase activity during development. (1993) (17)
A Comparison of Blinding and Afternoon Melatonin Injections on the Histology of the Reproductive Organs, Pineal Ultrastructure and Gonadotrophin Hormone Levels in Female Syrian Hamsters (1981) (16)
Epigenetic mechanisms in human physiology and diseases (2011) (16)
Melatonin as a putative protection against myocardial injury in COVID-19 infection (2020) (16)
The disaster in Japan: utility of melatonin in providing protection against ionizing radiation (2011) (16)
The pineal gland of the gerbil, Meriones unguiculatus (2004) (16)
Lipid and protein oxidation in hepatic homogenates and cell membranes exposed to bile acids (2009) (16)
Melatonin: A Potential Therapeutic Option for Breast Cancer (2020) (16)
Adrenergic regulation of type II 5'-deiodinase circadian rhythm in rat harderian gland. (1992) (16)
Melatonin and other indoles show antiviral activities against swine coronaviruses in vitro at pharmacological concentrations (2021) (16)
Porphyrin Metabolism in the Harderian Glands of Syrian Hamsters: In Vivo Regulation by Testicular Hormones, Lighting Conditions, Pineal Gland, and Pituitary Hormones (1992) (16)
Forskolin, an activator of adenylate cyclase activity, promotes large increases in N-acetyl transferase activity and melatonin production in the Syrian hamster pineal gland only during the late dark period. (1988) (16)
Circadian variation of beta-adrenoceptor binding sites in the pineal gland of the Syrian hamster and prevention of the nocturnal reduction by light exposure or propranolol treatment. (1989) (16)
Melatonin and Carbohydrate Metabolism in Plant Cells (2021) (16)
Melatonin role preventing steatohepatitis and improving liver transplantation results (2016) (16)
Melatonin Improves the Fertilization Capacity of Sex-Sorted Bull Sperm by Inhibiting Apoptosis and Increasing Fertilization Capacitation via MT1 (2019) (16)
Esophagoprotection mediated by exogenous and endogenous melatonin in an experimental model of reflux esophagitis (2013) (16)
Melatonin therapy in fibromyalgia (2006) (16)
Pineal noradrenaline levels in the Monogolian gerbil and in different strains of laboratory rats over a lighting regimen. (1977) (16)
Melatonin: new applications in clinical and veterinary medicine, plant physiology and industry. (2011) (16)
Melatonin synthesis enzymes interact with ascorbate peroxidase to protect against oxidative stress in cassava. (2020) (16)
Protective stabilization of mitochondrial permeability transition and mitochondrial oxidation during mitochondrial Ca2+ stress by melatonin's cascade metabolites C3‐OHM and AFMK in RBA1 astrocytes (2018) (16)
Research into the chronodisruption-cancer theory: the imperative for causal clarification and the danger of causal reductionism. (2010) (16)
Effect of shortened photoperiods on pineal serotonin n‐acetyltransferase activity and rhythmicity (1977) (16)
Interaction of ageing, photoperiod and melatonin on plasma thyroid hormones and cholesterol levels in female Syrian hamsters (Mesocricetus auratus). (1982) (15)
Attenuated nocturnal rise in pineal and serum melatonin in a genetically cardiomyopathic Syrian hamster with a deficient calcium pump (1991) (15)
COVID-19 pathophysiology: interactions of gut microbiome, melatonin, vitamin D, stress, kynurenine and the alpha 7 nicotinic receptor: Treatment implications (2020) (15)
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection (2022) (15)
N-acetyltransferase activity in the Harderian glands of the Syrian hamster, Mesocricetus auratus, is regulated by androgens and by hormones of the pituitary-thyroid axis. (1990) (15)
Decreases in pineal melatonin content during the hibernation bout in the golden-mantled group squirrel, Spermophilus lateralis. (1984) (15)
Radical-trapping and preventive antioxidant effects of 2-hydroxymelatonin and 4-hydroxymelatonin: Contributions to the melatonin protection against oxidative stress. (2017) (15)
Studies on pineal melatonin levels in a diurnal species, the Eastern chipmunk (Tamias striatus): Effects of light at night, propranolol administration or superior cervical ganglionectomy (2005) (15)
When the circadian clock meets the melanin pigmentary system. (2015) (15)
Melatonin: An atypical hormone with major functions in the regulation of angiogenesis (2020) (15)
Studies on the regulation of pineal melatonin production in the Richardson's ground squirrel (Spermophilus richardsonii). (1982) (15)
Ultrastructure of the pineal gland of the eastern chipmunk (Tamias striatus) (1982) (15)
Role of Melatonin on Virus-Induced Neuropathogenesis—A Concomitant Therapeutic Strategy to Understand SARS-CoV-2 Infection (2021) (15)
Central and Peripheral Actions of Melatonin on Reproduction in Seasonal and Continuous Breeding Mammals. (2020) (15)
The pineal gland of the gerbil, Meriones unguiculatus (1978) (15)
Characterization of β‐adrenoceptors in the syrian hamster harderian gland: Sexual differences and effects of either castration of superior cervical ganglionectomy (1989) (15)
Effects of Short‐Day Photoperiods and of N‐(2,4‐Dinitrophenyl)‐5‐Methoxytryptamine, a Putative Melatonin Antagonist, on Melatonin Synthesis in the Harderian Gland of the Syrian Hamster, Mesocricetus auratus (1990) (15)
Therapeutic targets of cancer drugs: Modulation by melatonin. (2020) (15)
ATOPIC DERMATITIS: MELATONIN AS POTENTIAL TREATMENT. (2015) (15)
Hypocotyl Elongation Inhibition of Melatonin Is Involved in Repressing Brassinosteroid Biosynthesis in Arabidopsis (2019) (15)
The effects of melatonin supplementation on blood pressure in patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trials (2019) (15)
Influence of hypophysectomy and prolactin on the rat pinealocyte: a quantitative ultrastructural study. (1982) (15)
Melatonin and Neonatal Sepsis: A Promising Antioxidant Adjuvant Agent (2017) (15)
Molecular Aspects of Melatonin Treatment in Tinnitus; a Review. (2019) (15)
Melatonin therapy for blunt trauma and strenuous exercise: A mechanism involving cytokines, NFκB, Akt, MAFBX and MURF-1 (2018) (14)
ß-Adrenergic stimulation prior to darkness advances the nocturnal increase of Syrian hamster pineal melatonin synthesis (1988) (14)
Melatonin: A mitochondrial resident with a diverse skill set. (2022) (14)
The Orbital Harderian Gland of the Male Atlantic Bottlenose Dolphin (Tursiops truncatus): A Morphological Study (2007) (14)
Melatonin and porphyrin in the harderian glands of the Syrian hamster: circadian patterns and response to autumnal conditions. (1990) (14)
Melatonin's efficacy in stroke patients; a matter of dose? A systematic review. (2020) (14)
Treatment with forskolin for 8 hours during the day increases melatonin synthesis in the Syrian hamster pineal gland in organ culture: The long lag period is required for RNA synthesis (1990) (14)
Melatonin prolongs graft survival of pancreas allotransplants in pigs (2011) (14)
Maternal Pineal Melatonin in Gestation and Lactation Physiology, and in Fetal Development and Programming. (2020) (14)
Transplantation of the Mammalian Pineal Gland: Studies of Survival, Revascularization, Reinnervation, and Recovery of Function (1993) (14)
Cellular and Molecular Actions of Melatonin as an Antioxidant (1997) (14)
The effects of the light:dark cycle and sympathetically-active drugs on pineal N-acetyltransferase activity and melatonin content in the Richardson's ground squirrel, Spermophilus richardsonii. (1982) (14)
Different patterns in the histology and autofluorescence of the Harderian glands of the Syrian Hamster, rat, mouse, Mongolian gerbil and guinea pig. (2001) (14)
Dynamic organization of endocrine networks. The neuroendocrine-reproductive axis and the pineal gland as examples. (1991) (14)
Immunoreactive somatostatin in the pineal gland of different rodent species: Circadian rhythm, effects of superior cervical ganglionectomy, pineal indole administration and lighting conditions (1984) (14)
Plant-derived melatonin from food: a gift of nature. (2021) (14)
Stimulatory effect of isoproterenol but not of dibutyryl cyclic AMP on N-acetyltransferase activity and melatonin content of Syrian hamster pineal gland in organ culture. (1988) (14)
Role of the sympathetic innervation in the cold-induced activation of 5'-deiodinase in brown adipose tissue of the Djungarian hamster. (1991) (13)
Responsiveness of Pineal N‐Acetyltransferase and Melatonin in the Cotton Rat Exposed to Either Artificial or Natural Light at Night (1985) (13)
Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders (2021) (13)
Melatonin inhibits luteinizing hormone releasing hormone (LHRH) induction of LH release from fetal rat pituitary cells (1995) (13)
Thyroid hormones in male hamsters with activated pineals or melatonin treatment. (1982) (13)
Effects of hereditary hypopituitarism and ectopic pituitary transplants on pinealocytes of the mouse: a quantitative ultrastructural study. (1982) (13)
Melatonin as the Hormone Which Mediates the Effects of the Pineal Gland on Neuroendocrine-Reproductive Axis of the Syrian Hamster (1983) (13)
In vivo stimulation of syrian hamster pineal melatonin levels by isoproterenol plus phenylephrine is not accompanied by a commensurate large increase in N-acetyltransferase activity (1989) (13)
Expression of Melatonin Synthesizing Enzymes in Helicobacter pylori Infected Gastric Mucosa (2013) (13)
Radical and Reactive Intermediate-Scavenging Properties of Melatonin in Pure Chemical Systems (2001) (13)
Comparison of changes in tryptophan and serotonin in regions of the hamster and the rat brain over a twenty-four hour period (1976) (13)
Melatonin; from pineal gland to healthy foods - (2011) (13)
Melatonin protects against lipid peroxidation induced by delta-aminolevulinic acid in rat cerebellum, cortex and hippocampus. (1998) (13)
Reproductive consequences of melatonin in mammals (1981) (13)
Natural and synthetic analogues of melatonin and related compounds II. Effects on plasma thyroid hormones and cholesterol levels in male Syrian hamsters (2005) (13)
Reactive Oxygen Species, DNA Damage, and Carcinogenesis: Intervention with Melatonin (2001) (13)
The pineal gland and cancer (1988) (13)
Melatonin enhances radiofrequency-induced NK antitumor immunity, causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development (2021) (13)
Oxidative changes in the liver, brain and lens of lipopolysaccharide-treated rats. (1995) (13)
Integration of Environmental Signals by the Pineal Gland and its Significance for Seasonality in Small Mammals (1991) (13)
Pineal function in the human: Implications for reproductive physiology (1986) (13)
Gender-associated differences in the development of 5-aminolevulinate synthase gene expression in the Harderian gland of Syrian hamsters (1993) (13)
Beta-adrenergic and peptide N-terminal histidine and C-terminal isoleucine stimulation of N-acetyl-transferase activity and melatonin production in the cultured rat pineal gland. (1992) (13)
mRNA transcription determines the lag period for the induction of pineal melatonin synthesis in the Syrian hamster pineal gland (1990) (13)
Fertility patterns in female mice following treatment with arginine vastocin or melatonin. (1976) (13)
Role of SIRT3/SOD2 signaling in mediating the antioxidant actions of melatonin in mitochondria (2017) (13)
Zinc finger of Arabidopsis thaliana 6 is involved in melatonin‐mediated auxin signaling through interacting INDETERMINATE DOMAIN15 and INDOLE‐3‐ACETIC ACID 17 (2018) (13)
Intrinsic rhythms of the pineal gland and associated hormone cycles in body fluids (1988) (13)
Melatonin as a rational alternative in the conservative treatment of resistant hypertension (2019) (13)
Interactions of melatonin, reactive oxygen species, and nitric oxide during fruit ripening: an update and prospective view (2022) (13)
The dual interplay of RAV5 in activating nitrate reductases and repressing catalase activity to improve disease resistance in cassava (2020) (13)
Acute effects of unilateral or bilateral superior cervical ganglionectomy on rat pineal N-acetyltransferase activity and melatonin content (1979) (13)
Delayed reproductive regression in male hamsters bearing intrarenal pituitary homografts and kept under natural winter photoperiods. (1979) (13)
Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications (2021) (13)
Brain Amines and Convulsions in Four Strains of Parathyroidectomized, Pinealectomized Rat (1978) (13)
Gut Microbiota Dysbiosis Induced by Decreasing Endogenous Melatonin Mediates the Pathogenesis of Alzheimer’s Disease and Obesity (2022) (13)
Luminal melatonin stimulates pancreatic enzyme secretion via activation of serotonin-dependent nerves. (2013) (13)
Influence of subcutaneous deposits of melatonin on the antigonadotrophic effects of blinding and anosmia in male rats. A dose-response study. (1980) (13)
Depression in Rat Pineal N‐Acetyltransferase Activity and Melatonin Content Produced by a Hind Leg Saline Injection is Time and Darkness Dependent (1987) (13)
Nocturnal Increase in the Sensitivity of the Syrian Hamster Pineal Gland to Isoproterenol Is Darkness Dependent 1 (1987) (12)
Nyctohemeral rhythmicity of type II thyroxine 5′-deiodinase activity in the pineal gland but not in the Harderian gland of the Swiss mouse (1991) (12)
The in vitro activation of cyclic AMP production by either forskolin or isoproterenol in the Syrian hamster pineal during the day is not accompanied by an increase in melatonin production. (1988) (12)
Effect of 6‐Methoxy‐2‐Benzoxazolinone on the Activities of Rat Pineal N‐Acetyltransferase and Hydroxyindole‐O‐Methyltransferase and on Melatonin Production (1990) (12)
Influence of the adrenal glands on DNA synthesis in normal and compensating kidneys. (1965) (12)
Stimuli-Responsive Nanocapsules for the Spatiotemporal Release of Melatonin: Protection against Gastric Inflammation (2019) (12)
Transient reduction in pineal melatonin levels but not n-acetyltransferase activity in rats forced to swim for 15 minutes at night (1988) (12)
Melatonin: Multifaceted messenger to the masses (1994) (12)
The Pineal gland (1984) (12)
Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species (2020) (12)
Melatonin is an appropriate candidate for breast cancer treatment: Based on known molecular mechanisms (2019) (12)
Melatonin and Cardioprotection in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2021) (12)
THE PINEAL GLAND: A REPORT OF SOME RECENT PHYSIOLOGICAL STUDIES (1967) (12)
Ultrastructure of rat pinealocytes during the last phase of pregnancy. (1982) (12)
Chronobiological aspects of the mammalian pineal gland. (1981) (12)
Age and food restriction alter the porphyrin concentration and mRNA levels for 5-aminolevulinate synthase in rat Harderian gland. (1992) (12)
Elevated Environmental Temperature Alters the Responses of the Reproductive and Thyroid Axes of Female Syrian Hamsters to Afternoon Melatonin Injections (1988) (12)
Melatonin: Reducing intracellular hostilities (2004) (12)
Potential Effects of Melatonin and Micronutrients on Mitochondrial Dysfunction during a Cytokine Storm Typical of Oxidative/Inflammatory Diseases (2021) (12)
Seasonal melatonin and luteinizing hormone rhythms in muskoxen at 52° N (1992) (12)
Part-time cancers and role of melatonin in determining their metabolic phenotype. (2021) (12)
Morphological and morphometric changes in the ovaries of white‐footed mice (Peromyscus leucopus) following exposure to long or short photoperiod (1983) (12)
Day-night differences in the number of pineal “synaptic” ribbons in two diurnal rodents, the chipmunk (Tamias striatus) and the ground squirrel (Spermophilus richardsonii) (2004) (12)
Pineal and retinal lysosomal enzyme rhythms (1987) (12)
A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude concepts. (2012) (12)
Breast Feeding and Melatonin: Implications For Improving Perinatal Health (2016) (12)
Melatonin and cannabinoids: mitochondrial-targeted molecules that may reduce inflammaging in neurodegenerative diseases. (2020) (12)
Effects of inhibition of thyroid function and of cold on melatonin synthesis and porphyrin content in the Harderian glands of male Syrian hamsters, Mesocricetus auratus. (1989) (12)
Brain norepinephrine levels in parathyroidectomized rats induced to convulse by pinealectomy (1975) (12)
Melatonin and related compounds: Chemical insights into their protective effects against oxidative stress (2017) (12)
Adrenocortical cytogenesis in the adult male golden hamster. A radioautographic study using tritiated-thymidine. (1967) (12)
Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas (2017) (12)
Depression of nocturnal pineal serotonin N-acetyltransferase activity in castrate male rats (2005) (11)
Seizures in rats induced by pinealectomy: influence of diazepam, chlordiazepoxide, diphenylhydantoin and pineal substances. (1973) (11)
Testosterone sensitive dihydropyridine binding in the Harderian gland of the male hamster. (1992) (11)
Characterization of nocturnal ultradian rhythms of melatonin in children with growth hormone-dependent and independent growth delay. (2001) (11)
Melatonin (2002) (11)
Melatonin metabolite, N(1)-acetyl-N(1)-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: in vivo and in vitro studies. (2016) (11)
Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation (2022) (11)
Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality (2022) (11)
Circadian rhythms in reproductive and thyroid hormones in gonadally regressed male hamsters exposed to natural autumn photoperiod and temperature conditions. (1994) (11)
Lack of pineal-induced gonadal regression in dark-exposed or blind hamsters after surgical isolation of the medial-basal hypothalamus. (1971) (11)
Failure of room light to inhibit pineal N-acetyltransferase activity and melatonin content in a diurnal species, the Eastern chipmunk (Tamias striatus) (1982) (11)
Regional distribution of immunoreactive somatostatin in the bovine pineal gland. (1989) (11)
Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells (2021) (11)
Ultrastructure of the blood vessels in the harderian gland of the hamster (mesocricetus auratus): Existence of sinusoids (1990) (11)
AGE DIFFERENCES IN CELLULAR PROLIFERATION IN RAT KIDNEYS. (1964) (11)
Formation of glutathione adducts of carbon tetrachloride metabolites in a rat liver microsomal incubation system. (1988) (11)
Melatonin and Pathological Cell Interactions: Mitochondrial Glucose Processing in Cancer Cells (2021) (11)
Melatonin synthesis genes N‐acetylserotonin methyltransferases evolved into caffeic acid O‐methyltransferases and both assisted in plant terrestrialization (2021) (11)
Corrigendum: Melatonin: Current Status and Future Perspectives in Plant Science (2016) (11)
Oxidative stress and persistent pulmonary hypertension of the newborn treated with inhaled nitric oxide and different oxygen concentrations (2012) (10)
Cellular proliferation and deoxyribonucleic acid synthesis in compensating kidneys of mice and the effect of food and water restriction. (1965) (10)
Melatonin supports alendronate in preserving bone matrix and prevents gastric inflammation in ovariectomized rats (2019) (10)
Relative Efficacy of Melatonin and 5‐Methoxytryptamine in Terms of Their Antigonadotrophic and Counterantigonadotrophic Actions in Male Syrian Hamsters (1984) (10)
Lysosomal Enzymes in the Rat Harderian Gland Are Altered by Either Bromocriptine Treatment or Hypophysectomy and Hormone Replacement Therapy 1 (1988) (10)
Involvement of the pineal gland in daily scheduling of the golden spiny mouse. (1998) (10)
Influence of Chronic Melatonin Availability on the Reproductive Quiescent Period in Male Hamsters Exposed to Natural Photoperiods during the Winter Months1 (1978) (10)
Melatonin metabolite, N1-acetyl-N1-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: in vivo and in vitro studies (2016) (10)
Melatonin and 6-methoxy-2-benzoxazolinone (6-MBOA) alter the response of the male Syrian hamster to natural photoperiod (1988) (10)
Neither the pituitary gland nor the sympathetic nervous system is responsible for eliciting the large drop in elevated rat pineal melatonin levels due to swimming (2005) (10)
Involvment of pineal indoles and polypeptides with the neuroendocrine axis. (1973) (10)
Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster - (2011) (10)
The influence of natural short photoperiodic and temperature conditions on plasma thyroid hormones and cholesterol in male Syrian hamsters (1984) (10)
Lighting the way: advances in transcriptional regulation and integrative crosstalk of melatonin biosynthetic enzymes in cassava. (2020) (10)
Twenty-four hour variation of α1-adrenergic receptors in the pineal gland of the male Syrian hamster (1989) (10)
Immunoreactive somatostatin diurnal rhythms in rat pineal, retina and Harderian gland: Effects of sex, season, continuous darkness and estrous cycle (2005) (10)
THE ROLE OF THE PINEAL GLAND AND OF ENVIRONMENTAL LIGHTING IN THE REGULATION OF THE ENDOCRINE AND REPRODUCTIVE SYSTEMS OF RODENTS. (1966) (10)
Darkness-induced changes in noradrenergic input determine the 24 hour variation in beta-adrenergic receptor density in the rat pineal gland: in vivo physiological and pharmacological evidence. (1988) (10)
Melatonin in ventricular and subarachnoid cerebrospinal fluid: Its function in the neural glymphatic network and biological significance for neurocognitive health. (2022) (10)
Increase of intra-ovarian oocyte release in PMSG-primed immature rats and its inhibition by arginine vasotocin (1983) (10)
Circadian rhythm in 5-aminolevulinate synthase mRNA levels in the Harderian gland of the Syrian hamster: Involvement of light:dark cycle and pineal function (1994) (10)
Targeting AMPK signaling in ischemic/reperfusion injury: From molecular mechanism to pharmacological interventions. (2022) (10)
Melatonin for cardioprotection in ST elevation myocardial infarction: are we ready for the challenge? (2016) (10)
Melatonin prevents delta-aminolevulinic acid-induced oxidative DNA damage in the presence of Fe2+. (2001) (10)
Changes in pineal indoleamine metabolism in vitamin A deficient rats. (1985) (10)
Effects of prepubertal manipulation with androgens on the development of sexual differences in the harderian glands of Syrian hamsters. (1991) (9)
Tyrosine hydroxylase activity in peripherally denervated rat pineal gland (1994) (9)
Melatonin as a potential inhibitor of kidney cancer: A survey of the molecular processes (2020) (9)
Melatonin Administration from 2000 to 2020 to Human Newborns with Hypoxic-Ischemic Encephalopathy (2020) (9)
Derivatives of [3H]serotonin in organ cultures of hamster pineal gland. (1984) (9)
Antioxidative Effects of Melatonin In Protection Against Cellular Damage Caused by Ionizing Radiation (44547) (2000) (9)
Global left ventricular longitudinal strain is associated with decreased melatonin levels in patients with acute myocardial infarction: a two-dimensional speckle tracking study (2013) (9)
N-acetyltransferase activity and melatonin concentrations in the Harderian glands of female Syrian hamsters: Alterations following either pinealectomy or bilateral superior cervical ganglionectomy (1988) (9)
Daily rhythms of body temperature in Acomys russatus: Their response to photoperiod manipulations and melatonin (1997) (9)
Pineal constituents and reproductive physiology. (1981) (9)
Influence of melatonin, constant light, or blinding on reproductive system of gerbils (Meriones unguiculatus) (1976) (9)
Carbaryl-induced changes in indoleamine synthesis in the pineal gland and its effects on nighttime serum melatonin concentrations. (1991) (9)
Effects of aggressive encounters on pineal melatonin formation in male gerbils (Meriones unguiculatus, Cricetidae) (1988) (9)
Inhibitory action of the pineal gland on the nuclear volume of thyroid follicular cells in male gerbils (Meriones unguiculatus). (2009) (9)
Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing (2021) (9)
Melatonin and the Optics of the Human Body (2019) (9)
Pineal N-acetyltransferase activity in hamsters maintained in shortened light cycles (1979) (9)
Testosterone increases N-acetyltransferase activity in both male and female Syrian hamster harderian glands. (1989) (9)
Activation of cerebrocortical type II 5′-deiodinase activity in Syrian hamsters kept under short photoperiod and reduced ambient temperature (1989) (9)
Stimulation of rat prolactin secretion in vivo by arginine vasotocin: influence of age of solution, nighttime administration, and dose. (1977) (9)
Age dependent changes in the susceptibility of parathyroidectomized, pinealectomized rats to seizures. (1973) (9)
A STUDY OF INDUCED RENAL HYPERPLASIA USING AUTORADIOGRAPHY. (1965) (9)
Pineal, pineal indoles and reproduction: retrospect and prospect (1984) (9)
Protein synthesis, but not RNA transcription, is required for the isoproterenol induced activation of type-II 5'-deiodinase activity in the rat pineal gland (1988) (9)
Evidence for the Benefits of Melatonin in Cardiovascular Disease (2022) (9)
Reproductive Involution in Male Hamsters Exposed to Naturally Increasing Daylengths after the Winter Solstice 1 (1980) (9)
Is melatonin deficiency a unifying pathomechanism of high risk patients with COVID-19? (2020) (9)
Melatonin as an Anti-Aging Therapy for Age-Related Cardiovascular and Neurodegenerative Diseases (2022) (9)
Early response of the hamster kidney to cold exposure and unilateral nephrectomy. (1968) (9)
Melatonin: A potential therapeutic agent against COVID-19 (2021) (9)
MELATONIN AND ITS ROLE IN NEURODEVELOPMENT DURING THE PERINATAL PERIOD: A REVIEW (2013) (9)
Melatonin-Pineal Relationships in Female Golden Hamsters 1 (1975) (9)
Melatonin-based therapeutics for atherosclerotic lesions and beyond: Focusing on macrophage mitophagy (2022) (9)
Rhythms in Pineal Immunoreactive Somatostatin in the Syrian Hamster, Mouse, and Gerbil (1988) (9)
An evaluation on the level of retinoids in the bovine pineal body. (1989) (9)
Letter to the Editor. Claude Bernard was right: hormones may be produced by "non-endocrine" cells. (2000) (9)
Chronodisruption and melatonin: the need for sensible exposure metrics in epidemiological studies (2008) (9)
Effects of intraventricular injections of 6‐hydroxydopamine on anterior pituitary cell proliferation (1984) (9)
A reciprocal relationship between the adenohypophysis and the pineal gland. (1982) (9)
Ultrastructure of pinealocytes of the cotton rat, Sigmodon hispidus (2004) (9)
Deficiency of immunoreactive somatostatin in the median eminence of Snell dwarf mice. (1985) (9)
Indole and porphyrin content of the syrian hamster harderian glands during the proestrous and estrous phases of the estrous cycle (1991) (9)
The Pineal and the Harderian Glands: Evidence for Mutual Interactions (1992) (8)
Melatonin as a potential inhibitor of colorectal cancer: Molecular mechanisms (2019) (8)
Low melatonin as a contributor to SARS-CoV-2 disease (2020) (8)
Melatonin as a hormone and an antioxidant: implications for organisms at high latitudes. (1997) (8)
Pineal actions and mechanisms in reproductive physiology (1981) (8)
Effects of Long and Short Photoperiod on the Ultrastructure of Pinealocytes of the Cotton Rat (Sigmodon hispidus) (1986) (8)
Diffuse neuroendocrine system and mitochondrial diseases: molecular and cellular bases of pathogenesis, new approaches to diagnosis and therapy. (2000) (8)
Identification of immunoreactive somatostatin in the rat Harderian gland: Regulation of its content by growth hormone, beta-adrenergic agonists and calcium channel blockers (1988) (8)
Effect of pinealectomy, binding, castration and melatonin on nerve growth factor levels in the submaxillary glands of mice (1978) (8)
β-Adrenoceptors in the extraorbital lacrimal gland of the Syrian hamster characterization with [125I]-iodopindolol and evidence of sexual dimorphism (2005) (8)
EMF and cancer [1] (1993) (8)
Different concentration of human cord blood HMGB1 according to delivery and labour: A pilot study (2018) (8)
Association of melatonin membrane receptor 1A/1B gene polymorphisms with the occurrence and metastasis of hepatocellular carcinoma (2017) (8)
Combination of melatonin with paclitaxel reduces the TLR4-mediated inflammatory pathway, PD-L1 levels, and survival of ovarian carcinoma cells (2022) (8)
Melatonin, cardiovascular disease and COVID-19: A potential therapeutic strategy? (2020) (8)
Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration (2022) (8)
Effects of either forskolin, the 1,9-dideoxy derivative of forskolin, or 8-bromocyclic AMP on cyclic AMP and melatonin production in the Syrian hamster pineal gland in organ culture (1989) (8)
Retinoids in the bovine pineal gland (1989) (8)
Swimming-Induced Suppression of Rat Pineal Melatonin is Prevented by Pretreatment with Calcium Channel Blockers 1 (1989) (8)
Melatonin inhibits human melanoma cells proliferation and invasion via cell cycle arrest and cytoskeleton remodeling (2020) (8)
Surgical procedures involving the pineal gland which prevent gonadal degeneration in adult male hamsters. (1972) (8)
Effect of drugs which inhibit tryptophan hydroxylase or dopamine-β-hydroxylase on pinealectomy-induced seizures in parathyroidectomized rats (1975) (8)
Pineal-induced ovarian atrophy in rats treated neonatally with testosterone. (1968) (8)
Novel Intracellular Actions of Melatonin: Its Relation to Reactive Oxygen Species (1996) (8)
Melatonin: Regulation of Prion Protein Phase Separation in Cancer Multidrug Resistance (2022) (8)
Elevation of cyclic GMP levels in the rat pineal gland induced by nitric oxide (1994) (8)
Melatonin confers enhanced polyamine metabolism and cell tolerance in Vitis vinifera against oxidative damage: Quantitative proteomic evidence (2022) (8)
Peripheral sympathetic innervation of the deep pineal gland of the golden hamster (1976) (8)
Different routes and formulations of melatonin in critically ill patients. A pharmacokinetic randomized study (2019) (8)
Circadian and non-circadian melatonin: Influences on glucose metabolism in cancer cells (2020) (8)
Not all shifts are equal: it's time for comprehensive exposure metrics in chronodisruption research. (2008) (8)
The pineal gland: From last to first (1993) (8)
Timing and neural pathways involved in release of luteinizing hormone after pregnant mare serum administration. (1972) (8)
Hormonal consequences of subcutaneous 6-methoxy-2-benzoxazolinone pellets or injections in prepubertal male and female rats. (1988) (8)
‘Distant socializing,’ not ‘social distancing’ as a public health strategy for COVID-19 (2021) (8)
Diurnal variation in uterine estrogen receptors in immature female rats--inhibition by arginine vasotocin. (1979) (8)
Suppression of nocturnal pineal N-acetyltransferase activity and melatonin content by inverted magnetic fields and induced eddy currents. (1993) (7)
Axelrod, the pineal and the melatonin hypothesis: lessons of 50 years to shape chronodisruption research. (2010) (7)
The Pineal gland during development : from fetus to adult (1986) (7)
Preantral intra-ovarian oocyte release in the white-footed mouse, Peromyscus leucopus (2004) (7)
New insights into the role of melatonin in photosynthesis. (2022) (7)
Nocturnal increase in pineal melatonin production in two lemming species, Dicrostonyx hudsonius and D. groenlandicus. (1990) (7)
Pretreatment with melatonin improves ovarian tissue cryopreservation for transplantation (2020) (7)
Metal ion homeostasis with emphasis on zinc and copper: Potential crucial link to explain the non-classical antioxidative properties of vitamin D and melatonin. (2021) (7)
In vivo administration of isoproterenol or forskolin during the light phase induces increases in the melatonin content of the Syrian hamster pineal gland without a rise in N-acetyltransferase activity (1990) (7)
Effects of altered photoperiod due to COVID-19 lockdown on pregnant women and their fetuses (2020) (7)
INJECTIONS AND/OR IMPLANTS OF 6-CHLOROMELATONIN AND MELATONIN: EFFECTS ON PLASMA THYROID HORMONES IN MALE AND FEMALE SYRIAN HAMSTERS (1984) (7)
Lindane may enhance nocturnal pinealN-acetyltransferase activity via β-adrenergic receptors (1991) (7)
11 – The Pineal Gland and Melatonin Synthesis: Their Responses to Manipulations of Static Magnetic Fields (1994) (7)
No difference in day‐night serum melatonin concentration after pineal grafting into the third cerebral ventricle of pinealectomized rats (1991) (7)
Pulmonary function changes in rats with taurocholate‐induced pancreatitis are attenuated by pretreatment with melatonin (2014) (7)
Perfusion of melatonin into the prefrontal cortex disrupts the circadian rhythm of acetylcholine but not of locomotor activity (2003) (7)
Fine‐tuning of pathogenesis‐related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight (2021) (7)
Tunneling nanotubes and mesenchymal stem cells: New insights into the role of melatonin in neuronal recovery (2022) (7)
Antioxidant and Anti-Inflammatory Role of Melatonin in Alzheimer’s Neurodegeneration (2014) (7)
Risk, compensation, challenges (2009) (7)
The chronosense -- what light tells man about biological time. (2004) (7)
The pineal gland and its hormones : fundamentals and clinical perspectives (1995) (7)
The Absence of Pineal Melatonin Abolishes the Daily Rhythm of Tph1 (Tryptophan Hydroxylase 1), Asmt (Acetylserotonin O-Methyltransferase), and Aanat (Aralkylamine N-Acetyltransferase) mRNA Expressions in Rat Testes (2019) (7)
Acute effects of a single afternoon melatonin injection on LH, prolactin, and pineal melatonin titers in the Syrian hamster (1984) (7)
Melatonin; an Established Radioprotective Agent Against Japan and #8217;s Nuclear Disaster (2011) (7)
Role of extracellular calcium on the regulation of melatonin synthesis in the Syrian hamster pineal gland (2001) (7)
Effect of calcium on melatonin secretion in chick pineal gland I (1996) (7)
Influence of radiotherapy on 6-sulphatoxymelatonin levels in the urine of brain cancer patients. (2000) (7)
The Mechanism of Oral Melatonin Ameliorates Intestinal and Adipose Lipid Dysmetabolism Through Reducing Escherichia Coli-Derived Lipopolysaccharide (2021) (7)
Melatonin and the pathophysiology of cellular membranes (2010) (7)
Chronic administration of sublethal doses of carbaryl increases pineal N‐acetyltransferase and hydroxyindole‐O‐methyltransferase activities and serum melatonin levels (1991) (7)
Urgent search for safe and effective treatments of severe acute respiratory syndrome: is melatonin a promising candidate drug? (2003) (7)
Possible mechanisms of TSH--independent thyroid growth. (1984) (7)
Melatonin protects against lead acetate induced oxidative stress-mediated changes in morphology and metabolic status in rat red blood cells: a flow cytometric and biochemical analysis (2016) (7)
High mobility group box 1 and markers of oxidative stress in human cord blood (2019) (7)
Coadministration of Melatonin and Insulin Improves Diabetes-Induced Impairment of Rat Kidney Function (2021) (7)
Daily Propranolol Administration Reduces Pineal Concretion Formation in the Mongolian Gerbil 1 (1986) (7)
The synthesis and the structure elucidation of N,O-diacetyl derivative of cyclic 3-hydroxymelatonin (2004) (7)
Electron microscopic observations on neuron-like cells in the ground squirrel pineal gland (2005) (7)
Melatonin counteracts the 5-aminolevulinic acid-induced rise of rat forebrain tryptophan and serotonin concentrations at night (1990) (7)
Ultrastructure of pinealocytes of the kangaroo rat (Dipodomys ordi) (2004) (6)
Melatonin Synthesis in Fermented Foods (2017) (6)
Regulation of Pituitary Gonadotropins by the Mammalian Pineal Gland1 (1976) (6)
N-methyl-D-aspartate does not prevent effects of melatonin on the reproductive and thyroid axes of male Syrian hamsters. (1992) (6)
Rate of reproductive involution following either exposure to short days or daily administration of melatonin is faster in inbred than in random-bred female Syrian hamsters. (1989) (6)
A Novel Melatonin Antagonist, N-(2,4-Dinitrophenyl)-5-Methoxytryptamine Neutralizes Some Effects of Melatonin in the Female Syrian Hamster (1989) (6)
Treatment of sleep disorders with melatonin (2012) (6)
Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved (2021) (6)
Arginine vasotocin alters hamster pituitary LH and prolactin secretion in vitro. (1982) (6)
Interaction of harderian glands, illumination, and temperature on thyroid hormones in golden hamsters (2004) (6)
Melatonin, sleep, and prostate cancer in elderly men: study, hypothesis development, and icelandic options. (2015) (6)
Parathion (O,O-dimethyl-O-p-nitrophenyl phosphorothioate) induces pineal melatonin synthesis at night (1991) (6)
Hydroxyindole‐O‐methyltransferase activity in the pineal gland of the muskox (Ovibos moschatus) (1994) (6)
A circannual rhythm in bovine pineal serotonin (1980) (6)
Frog transparency led to discovery of melatonin (2008) (6)
Effects of ethylene glycol tetraacetic acid, A23187 and calmodulin, calcium activated neutral proteinase antagonists on melatonin secretion in perifused chick pineal gland (1998) (6)
Effects of the pineal gland on reproductive organ growth and fertility in dual sensory deprived female rats. (1972) (6)
Failure to stimulate melatonin synthesis in the rat pineal gland with an adenosine analog (1992) (6)
Extrapineal melatonin: sources, regulation, and potential functions (2014) (6)
Influence of melatonin or 5-methoxytryptamine on the nuclear volume of thyroid follicular cells in the syrian hamster (Mesocricetus cuiratus) (1986) (6)
Chronobiology : its role in clinical medicine, general biology, and agriculture : proceedings of the XIX International Conference of the International Society for Chronobiology, held in Bethesda, Maryland, June 20-24, 1989 (1990) (6)
Factors controlling melatonin rhythmicity in the pineal gland of the Syrian hamster (1986) (6)
Melatonin inhibition of pineal antigonadotrophic activity in male rats. (1975) (6)
Analysis of constant tissue remodeling in Syrian hamster Harderian gland: intra‐tubular and inter‐tubular syncytial masses (2013) (6)
Daily time course of the contents in monoamines and their metabolites in the pineal gland of Syrian hamster (1997) (6)
Seasonal Reproductive Events Related to the Pineal Gland (1983) (6)
Natural and synthetic analogues of melatonin and related compounds I. Effects on the reproductive system of the male Syrian hamster (1983) (6)
Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments. (2022) (6)
Cysteamine effects on somatostatin, catecholamines, pineal NAT and melatonin in rats (1986) (6)
Vasoactive intestinal peptide stimulates N‐acetyltransferase and hydroxyindole‐O‐methyltransferase activities and melatonin production in cultured rat but not in Syrian hamster pineal glands (1992) (6)
Chronic N-methyl-D-aspartate administration prevents melatonin-associated changes in cell differentiation in the harderian glands of male hamsters. (1993) (6)
The pineal gland: A model for adrenergic modulation of ubiquitin ligases (2017) (6)
Melatonin as a Therapeutic Agent for the Inhibition of Hypoxia-Induced Tumor Progression: A Description of Possible Mechanisms Involved (2021) (6)
Circadian rhythms of serum melatonin and prolactin in the Rhesus monkey (Macaca mulatta) (1981) (6)
The protective effects of melatonin on organisms against the environmental pollutants of heavy metal and non-mental toxins (2019) (6)
Dose-dependent beneficial effect of melatonin on obesity; interaction of melatonin and leptin (2019) (6)
The adrenal response of hamsters, gerbils and rats to exogenous corticotrophin or unilateral adrenalectomy. (1967) (6)
Pineal sensitivity to nighttime swimming stress changes during the active season in Richardson's ground squirrels (Spermophilus richardsonii). (1989) (6)
Effects of hormones on the renal response to unilateral nephrectomy in hypophysectomized rats. (1967) (6)
Influence of intraocularly-injected pineal indoles on PMS-induced ovulation in immature rats. (1974) (6)
Cerebral Modulation of Circadian Sleep-Wake Rhythms (2011) (6)
PP2C1 fine‐tunes melatonin biosynthesis and phytomelatonin receptor PMTR1 binding to melatonin in cassava (2022) (6)
Melatonin stimulation of prolactin secretion in male rats: Influence of pinealectomy, castration or gonadal steroid pretreatment (1981) (6)
Undernutrition potentiates melatonin effects in maturing female rats (1989) (6)
Effects of gender, age, and castration on porphyrin concentration and melatonin synthesis in the Harderian glands of the Mongolian gerbil, Meriones unguiculatus (1991) (6)
Effect of several androgens, cyproterone acetate or estrogen-progesterone on the prolactin-releasing activity of arginine vasotocin in castrated male rats (1978) (6)
Correction: The Effects of Melatonin Supplementation on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2018) (5)
Detection of Serotonin, Melatonin, and Their Metabolites in Honey. (2021) (5)
Ovarian response of pinealectomized and intact white-footed mice kept under naturally short photoperiods (1981) (5)
The effects of arginine vasotocin on pregnant Mare's serum-induced ovulation in the immature female rat. (1978) (5)
Melatonin action on the time course of compensatory ovarian hypertrophy in the Swiss-Webster mouse. (1972) (5)
Evidence for an endocrine function of the human pineal gland. Chairman's introduction. (1978) (5)
The effect of twice daily gonadotropin-releasing hormone (GnRH) administration and/or renal pituitary homografts on melatonin-induced gonadal atrophy in male Syrian hamsters. (1982) (5)
Effect of delaying melatonin injections on the inhibition of compensatory ovarian hypertrophy in mice. (1971) (5)
Interaction between pargyline, a monoamine oxidase inhibitor, and beta-adrenergic receptors in the rat pineal gland. (1982) (5)
Failure of inbreeding to influence pineal-induced gonadal regression in short day exposed hamsters. (1983) (5)
Melatonin inhibits Gram-negative pathogens by targeting citrate synthase (2022) (5)
[Ca2++Mg2+]-dependent ATPase activity in rat pineal gland (1993) (5)
Blood melatonin level can serve as a potential biomarker for prostate and hepatocellular carcinomas (2021) (5)
Influence of melatonin on the testicular regression induced by subcutaneous testosterone pellets in male rats kept in long or short photoperiod. (1988) (5)
Timing is everything: Circadian rhythms and their role in the control of sleep (2022) (5)
The potential role of melatonin in controlling the annual reproductive cycle of hamsters (1978) (5)
The Oxidant/Antioxidant network (1999) (5)
Sexual differences in 5′‐deiodinase activity in the harderian gland of Syrian hamsters and the effect of pinealectomy: Regulation by androgens (1996) (5)
Type II Thyroxine 5′‐Deiodinase Activity in the Rat Brown Adipose Tissue, Pineal Gland, Harderian Gland, and Cerebral Cortex: Effect of Acute Cold Exposure and Lack of Relationship to Pineal Melatonin Synthesis (1990) (5)
Nuclear and Cytoplasmic Inclusion Bodies in Pinealocytes of the Cotton Rat, Sigmodon hispidus: An Electron Microscopic Study (1984) (5)
A possible mechanism of rapid luteolysis in white‐footed mice, Peromyscus leucopus (1983) (5)
Sleep duration, melatonin and breast cancer in the Singapore Chinese Health Study: On null results and their interpretation (2013) (5)
Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster. (1985) (5)
A hypothetical role for autophagy during the day/night rhythm‐regulated melatonin synthesis in the rat pineal gland (2021) (5)
Melatonin suppression by time-varying and time-invariant electromagnetic fields (1996) (5)
Cholelithiasis, oxidative stress and melatonin. (2001) (5)
Oxidative Mediated Neurodegeneration in Alzheimers Disease: Melatonin and Related Indoles as Neuroprotective Agents (2003) (5)
Injections of alpha-melanocyte stimulating hormone affect pineal serotonin, melatonin and N-acetyltransferase activity. (1987) (5)
Effects of injections and/or subcutaneous implants of melatonin on pituitary and plasma levels of LH, FSH and PRL in ovariectomized Syrian hamsters (1979) (5)
Processes Underlying Chronodisruption and Their Proposed Association with Illness (2013) (5)
The involvement of brain amines in pinealectomy-induced convulsions in the gerbil I. Serotonin (1981) (5)
Melatonin: A hypothesis regarding its use to treat Wilson disease. (2019) (5)
The Ageing Pineal Gland and Its Physiological (1992) (5)
Delta-aminolevulinic acid-induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: an in vitro and in vivo study. (1998) (5)
Melatonin reduces oxidative catastrophe in neurons and glia (2010) (5)
Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging (2017) (5)
Influence of arginine vasotocin on the estrogen-induced surge of LH and FSH in adult ovariectomized rats. (1978) (5)
Restoration of fertility in light-deprived female hamsters by chronic melatonin treatment (2004) (5)
Role of postsynaptic alpha-adrenergic receptors in the beta-adrenergic stimulation of melatonin production in the Syrian hamster pineal gland in organ culture. (1989) (5)
Thyroxine 5'‐deiodinase type II activity in chick pineal and Harderian gland: Nyctohemeral rhythmicity and its regulation by noradrenergic input (1993) (5)
Circadian Aspects of the Cellular Redox State: Melatonin Actions and Implications for Oncogenesis (2000) (5)
The pineal body and pinealectomy in the cotton rat, Sigmodon hispidus. (1980) (5)
Melatonin Salvages Neural Tissue from Ischemia/Reperfusion Injury (2010) (5)
Serum luteinizing hormone, prolactin, and thyrotropin and their pituitary subunit mRNA levels during proestrus in the Syrian hamster. (1991) (5)
Understanding the oncostatic actions displayed by melatonin in colorectal cancer therapy. (2020) (5)
Occurrence of preantral intra-ovarian oocyte release in the rat and the Syrian hamster (Mesocricetus auratus) (2004) (5)
Nighttime immunoreactive somatostatin content of the median eminence in hypo- and hyperthyroid rats. (1985) (4)
Preventing cancers caused by chronodisruption: blocking blue light alone is unlikely to do the trick. (2009) (4)
Circadian rhythm and pharmacologic regulation of the monodeiodination of 3,3',5,5'-tetraiodothyronine in the pineal gland. (1992) (4)
Nyctohemeral rhythms of gonadal, thyroid and pineal function in the hyperprolactinemic male rat. (1988) (4)
Melatonin: A hypothesis for Kawasaki disease treatment. (2018) (4)
7 Melatonin : clinical relevance (2003) (4)
Gastric Toxicity and Mucosal Ulcération Induced by Oxygenderived Reactive Species (2001) (4)
Pineal-Harderian Gland Interactions: Morphological and Physiological Evidences for an Endocrine Function of the Syrian Hamster Harderian Gland (1991) (4)
Adenosine effects on the rat pineal gland in vitro: Cyclic adenosine monophosphate levels, N‐acetyltransferase, and thyroxine type II 5′‐deiodinase activities and melatonin production (1991) (4)
Iron decreases the nuclear but not the cytosolic content of the neurohormone melatonin in several tissues in chicks (1996) (4)
Melatonin synthesis in the pineal gland of the Richardson's ground squirrel (Spermophilus richardsonii): Influence of age and insulin-induced hypoglycemia (2005) (4)
Intracellular Actions of Melatonin with a Summary of Its Interactions with Reactive Oxygen Species (1995) (4)
The influence of pineal activation, removal or denervation on hypothalamic luteinizing hormone-releasing hormone activity: An in vitro study (1975) (4)
Changes in nocturnal pineal indoleamine metabolism in rats treated with parathion are prevented by beta-adrenergic antagonist administration. (1995) (4)
Neurotoxicity of dextrorphan. (1999) (4)
Assessment of Melatonin-Cultured Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials for Wound Healing (2022) (4)
Day-night differences in estimated rates of 5-hydroxytryptamine turnover in the rat pineal gland (2004) (4)
Inhibition of 5 alpha-reductase does not simulate the effects of androgen deprivation on porphyrin metabolism by harderian glands from the male Syrian hamster. (1991) (4)
Physiological effects of the pineal gland in androgen-sterilized female rats. (1970) (4)
A quantitative ultrastructural study of the pinealocyte of the chipmunk (Tamias striatus) during the daytime and at night (1982) (4)
Alpha-melanocyte stimulating hormone: a circadian rhythm in the hamster pineal gland (1986) (4)
Effects of pinealectomy and melatonin or 5-methoxytryptamine on testicular LH and PRL receptors in Syrian hamsters (Mesocricetus auratus). (1988) (4)
Melatonin as an inducer of arecoline and their coordinated roles in anti-oxidative activity and immune responses. (2020) (4)
Melatonin: Both a Messenger of Darkness and a Participant in the Cellular Actions of Non-Visible Solar Radiation of Near Infrared Light (2023) (4)
Pineal melatonin rhythm (1980) (4)
Dark exposure inhibits the mitotic activity of thyroid follicular cells in male mice with intact pineal (1984) (4)
Non-visible electromagnetic radiation and pineal function (1994) (4)
Pineal‐induced alterations in reproductive function and pituitary prolactin in the female rat: The effects of bilateral superior cervical ganglionectomy and nervi conarii transection (1977) (4)
Melatonin: History, Biosynthesis, and Assay Methodology (2020) (4)
Insensitivity of the reproductive system of pinealectomized superior cervical ganglionectomized male Syrian hamsters to twice daily injections of melatonin (1985) (4)
Phytomelatonin as a central molecule in plant disease resistance. (2022) (4)
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy. (2022) (4)
Ultrastructure of the pineal gland of the brush mouse (Peromyscus boylei): Influence of long and short photoperiod (1983) (4)
Effects of acute cold exposure at night on pineal N-acetyltransferase activity and melatonin content in white-footed mice, Peromyscus leucopus. (1990) (4)
Melatonin and cancer suppression: insights into its effects on DNA methylation (2022) (4)
Hyperactivity in the blind-anosmic female rat: Role of the pineal gland (1977) (4)
Underfeeding and Exposure to Short Photoperiod Alters Rat Pineal and Harderian Gland Lysosomal Enzyme Activities 1 (1988) (4)
Introduction to the Symposium: A Précis of the Pineal Odyssey (1970) (3)
Influence of ovariectomy and estrogen and/or progesterone treatment on pituitary and plasma LH and prolactin levels in female hamsters. (1974) (3)
Therapeutic Potential of Melatonin (Preliminary Pages) (1997) (3)
Effect of photoperiod and pineal indoles on the reproductive system of young female white-footed mice (2005) (3)
N-acetyltransferase activity in the Syrian hamster Harderian gland is independent of the noradrenergic and cholinergic inputs to the gland (1989) (3)
Effect of long and short photoperiod and/or pinealectomy on immunoreactive somatostatin in the Syrian hamster. (1985) (3)
Seasonal aspects of reproduction in hibernatory rodents: Photoperiodic and pineal effects (1981) (3)
Rationale for the use of melatonin as a protective agent against cosmic radiation and ischemia-reperfusion damage in long term spaceflight (2006) (3)
Follicular growth and intraovarian and extraovarian oocyte release after daily injections of melatonin and 6-chloro-melatonin in the Syrian hamster. (1983) (3)
Neural glymphatic system: Clinical implications and potential importance of melatonin (2021) (3)
Melatonin Reprograms Glucose Metabolism in Cancer Cell Mitochondria (2019) (3)
[Function of the pineal body in cancer and aging]. (1990) (3)
TIME TO TREATMENT WITH MELATONIN AND INFARCT SIZE IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: INSIGHTS FROM THE MARIA (MELATONIN ADJUNCT IN THE ACUTE MYOCARDIAL INFARCTION TREATED WITH ANGIOPLASTY) TRIAL (2017) (3)
Scanning Electron Microscopy of the Superficial Pineal Gland of the 15‐day‐old rat (Rattus norvegicus) (2004) (3)
Functional Morphology of the Mammalian Pineal Gland (1996) (3)
Adrenalectomy but not gonadectomy affects rat pineal β-adrenergic receptor density (1988) (3)
NATURAL DECREASING TEMPERATURE AND PHOTOPERIOD CONDITIONS OR ACUTE COLD EXPOSURE AFFECT CIRCULATING THYROID HORMONES, SERUM CHOLESTEROL AND TYPE II 5-DEIODINASE IN BROWN ADIPOSE TISSUE IN THE TRUMPET-TAILED RAT, OCTODON DEGUS (1989) (3)
On the occurrence of a myeloid body in pinealocytes of the white-footed mouse, Peromyscus leucopus (2004) (3)
Antioxidant activity of pineal methoxyindoles on hepatocyte plasmatic membrane (2019) (3)
Role of the Antioxidant Melatonin in Regulating Autophagy and Mitophagy (2014) (3)
Melatonin: It's not Just for the Endocrine System Anymore Melatonin in the Promotion of Health, edited by Ronald R. Watson (1999) (3)
Melatonin drives beneficial Sirtuin 1 expression in leptin-deficient mice liver through MT1 receptor (2015) (3)
Chronomedicine: an old concept's fledging? A selective literature search. (2012) (3)
Resveratrol and Cervical Cancer: A New Therapeutic Option? (2022) (3)
Pituitary and plasma prolactin levels in male rats as influenced by the pineal gland. (1974) (3)
Interaction of luteinizing hormone-releasing hormone, cyproterone acetate and arginine vasotocin on plasma levels of luteinizing hormone in intact and castrated adult male rats (1979) (3)
FLUCTUATIONS IN MELATONIN CONTENT AND ITS EFFECTS ON THE AGEING PROCESS OF LETTUCE SEEDS DURING STORAGE (2021) (3)
Pinoline and melatonin protect against H2O2-induced lipid peroxidation in rat brain homogenates (1998) (3)
Mo-P5:349 The melatonin adjunct in the acute myocardial infarction treated with primary angioplasty: Study design and rationale (Maria trial) (2006) (3)
A perinatal signature of light on chronobiology? If so, numerous questions arise and experimental animal research must provide more information. (2012) (3)
Further studies on the regulation of n-acetyltransferase activity and melatonin content in the syrian hamster pineal gland (1984) (3)
Influence of delta-sleep inducing peptide on melatonin synthesis in the rat pineal gland. (1986) (3)
Influence of pinealectomy on serum estrogen and progesterone levels in blind-anosmic female rats (1978) (3)
Hormonal modulation of pineal melatonin synthesis in rats and syrian hamsters: Effects of adrenalectomy and corticosteroid implants (2005) (3)
Impact of photoperiodic information on pineal metabolism and physiology. (1985) (3)
Ethanol preference as a function of the pineal gland (1973) (3)
Influence of psoralen on NAT activity and melatonin levels in rat pineal gland during the daily period of darkness. (1987) (3)
Pineal lysosomal enzymes in the Syrian hamster: circadian rhythm and effects of castration or short photoperiod treatment (1989) (3)
Reduced dopamine synthesis and protein levels in the median eminence of blinded anosmic female rats: relation to the pineal. (1982) (3)
The organochlorine insecticide 1,2,3,4,5,6-hexachlorocyclohexane (lindane) but not 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) augments the nocturnal increase in pineal N-acetyltransferase activity and pineal and serum melatonin levels (1990) (3)
Melatonin as an Agent for Cardioprotection in Patients with ST-Elevation Myocardial Infarction and Short Ischaemic Time (2017) (3)
Adrenalectomy or superior cervical ganglionectomy modifies the nocturnal increase in rat pineal type II thyroxine 5'-deiodinase. (1993) (3)
Influence of δ-sleep inducing peptide on melatonin synthesis in the rat pineal gland (1986) (3)
Photoreceptor damage and eye pigmentation (1985) (3)
The potential utility of melatonin in the treatment of childhood cancer (2019) (3)
Differential and Overlapping Effects of Melatonin and Its Metabolites on Keratinocyte Function: Bioinformatics and Metabolic Analyses (2021) (3)
Effects of long-term treatment with melatonin or melatonin plus ectopic pituitary transplants on testicular LH/hCG and prolactin receptors in juvenile Syrian hamsters (Mesocricetus auratus). (1986) (3)
Advances in pineal research (1986) (3)
Pituitary and plasma levels of luteinizing hormone and prolactine in the immature female rat following administration of pregnant mares' serum. (1975) (3)
Remembrance: growing up with the pineal gland: early recollections. (1992) (3)
Transient responses of melatonin to stress (2022) (3)
Circadian variation in acute myocardial infarction size: Likely involvement of the melatonin and suprachiasmatic nuclei. (2017) (3)
Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines, Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple Negative Breast Cancer (2022) (3)
Scanning Electron Microscopy of the Orbital Harderian Gland in the Male Atlantic Bottlenose Dolphin (Tursiops truncatus) (2009) (3)
Molecular interactions of melatonin with lipid rafts (2022) (3)
Synergistic Effect of Melatonin and Selenium Improves Resistance to Postharvest Gray Mold Disease of Tomato Fruit (2022) (3)
Premarin Reduces Neurodegeneration and Promotes Improvement of Function in an Animal Model of Spinal Cord Injury (2022) (3)
Serotonin, melatonin and their precursors and metabolites and vitamin D3 derivatives in honey (2022) (3)
Early Treatment of Acute Myocardial Infarction with Melatonin: Effects on MMP-9 and Adverse Cardiac Events (2022) (3)
Strategies to generate melatonin-enriched transgenic rice to respond to the adverse effects on rice production potentially caused by global warming (2021) (3)
Gastrointestinal tract and melatonin: Reducing pathophysiology (2010) (3)
Newborn intensive care units and perinatal healthcare: on light’s imprinting role on circadian system stability for research and prevention (2013) (3)
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy. (2022) (3)
Inclusion bodies in pinealocytes of the cotton rat (Sigmodon hispidus) (2004) (3)
Reduced melatonin levels may facilitate glioblastoma initiation in the subventricular zone (2022) (3)
Neuropsychiatric Consequences of COVID-19 Pandemic: A Synthetic Review from a Global Perspective (2022) (3)
Effects of melatonin on the Harderian gland of lipopolysaccharide-treated rats: morphological observations. (1999) (3)
Phototransduction‐related circadian changes in indoleamine metabolism in the chick pineal gland in vivo (1993) (3)
The Pineal Gland of Mammals: Some Open Morphological Questions (1991) (2)
Melatonin, coronavirus, cardiovascular disease, and the geriatric emergency: let's use everything we have! (2020) (2)
Chronobiology, melatonin, and sleep in infants and children (2002) (2)
Circadian rhythm of type II thyroxine-5'-deiodinase activity in the pineal gland: Controlling factors (1988) (2)
Clinical cardiovascular emergencies and the cellular basis of COVID-19 vaccination: from dream to reality? (2022) (2)
Differential responses of rat pineal thyroxine type II 5′-deiodinase andN-acetyltransferase activities to either light exposure, isoproterenol, phenylephrine, or propranolol (1988) (2)
UTERINE KERATINIZING METAPLASIA AND PLASMA LEVELS OF VITAMIN A IN RATS FED VITAMIN A-DEFICIENT DIETS. (1965) (2)
The effects of melatonin, N-acetylserotonin, and 6-hydroxymelatonin on the ultrastructure of the pinealocytes of the Syrian hamster (Mesocricetus auratus). (2006) (2)
Melatonin and mitochondrial function during ischemia/reperfusion injury (2017) (2)
Melatonin as the neuroendocrine signal (1987) (2)
Harderian gland porphyrin, lysosomal and type II 5'-deiodinase rhythms in Sprague-Dawley and Fischer-344 rats kept under chronic long- or short-photoperiod conditions. (1991) (2)
Melatonin use for SARS‐CoV‐2 infection: Time to diversify the treatment portfolio (2022) (2)
Pyrimidine and purine salvage deoxyribonucleoside metabolism in hepatic and renal homogenates from rats pretreated with propylthiouracil or L-thyroxine. (2000) (2)
Diurnal sensitivity of the neuroendocrine-reproductive axis to the antigonadotrophic influence of melatonin in male Syrian hamsters with experimentally altered cortisol rhythms. (1985) (2)
Efficacy and safety of melatonin in newborn infants (2012) (2)
Melatonin Protects Against Stress-InducedGastric Lesions by Scavenging the HydroxylRadical (2000) (2)
Differential adrenergic regulation of rat pineal cyclic AMP production and N-acetyltransferase activity during postnatal development: involvement of G alpha s and G alpha i1-2 proteins. (1997) (2)
Lindane may enhance nocturnal pineal N-acetyltransferase activity via beta-adrenergic receptors. (1991) (2)
The midline pineal "eye" (1995) (2)
Influence of diet on photoperiod-induced gonadal regression in female hamsters. (1987) (2)
Pineal inhibition of compensatory testicular enlargement in light-deprived hamsters (1970) (2)
Effect of removal of the Harderian glands on pineal melatonin concentrations in the Syrian hamster (1979) (2)
Molecular mechanisms of melatonin’s protection against high-LET radiation: implications for space travel (2020) (2)
The protective effects of melatonin on organisms against the environmental pollutants of heavy metal and non-metal toxins (2020) (2)
Evidence that olfactory bulbectomy does not influence testicular regression in golden hamsters on short photoperiod by altering pineal melatonin production (2004) (2)
THE PINEAL GLAND: ANOTHER PERSPECTIVE (1975) (2)
Rationale for the continued use of melatonin to combat the delta variant of SARS-CoV-2 (2021) (2)
Melatonin, tunneling nanotubes and anastasis: Cheating cell death (2021) (2)
New Aspects Concerning the Regulation of Pineal Indoleamine Metabolism: Implications for Neuroimmunology (1991) (2)
Melatonin ameliorates arsenic-induced cardiotoxicity through the regulation of the Sirt1/Nrf2 pathway in rats. (2023) (2)
Pineal removal or denervation: Effects on hypothalamic PRF activity in the rat (1978) (2)
Night-time rise in rat pineal N-acetyltransferase due to carbaryl administration is reduced by propranolol treatment. (1995) (2)
Pleiotropic role of melatonin in brain mitochondria of obese mice (2020) (2)
Pineal lysosomal enzyme circadian rhythms in male hamsters exposed to natural decreasing photoperiod and temperature conditions (1990) (2)
Bioactive peptides of plant origin: distribution, functionality, and evidence of benefits in food and health. (2022) (2)
Oxidative Stress of Newborn (2012) (2)
Evidence for pineal induced seasonal changes in reproductive physiology of male hamsters kept under natural environmental conditions (1973) (2)
Unusual cytoplasmic inclusion bodies in the pinealocytes of the cotton rat (Sigmodon hispidus). (1982) (2)
Modification by adrenergic blocking agents of arginine vasotocin-induced prolactin secretion in vitro (1977) (2)
Pineal rhythms: Modification by drugs and light (1984) (2)
Potentiating the Benefits of Melatonin through Chemical Functionalization: Possible Impact on Multifactorial Neurodegenerative Disorders (2021) (2)
The mammalian pineal gland: its adaptive significance for reproductive responses to environmental changes (1987) (2)
Correction: The effects of melatonin supplementation on blood pressure in patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trials (2019) (2)
Norepinephrine stimulation of rat pineal type II thyroxine 5'-deiodinase (1990) (2)
Melatonergic index as a prognostic biomarker of reproductive organ cancers: correlations with metabolic parameters as well as clock genes PER1 and TIMELESS (2021) (1)
Therapeutic potential of melatonin : 2nd Locarno Meeting on Neuroendocrinoimmunology, Locarno, May 5-8, 1996 (1997) (1)
Neurosecretion in the pineal gland ofMacaca rhesus (1974) (1)
Karyometric studies of thyroid follicular cells and thyroid hormone secretion in the male Syrian hamsters following melatonin and diazepam administration (1991) (1)
We are not alone: Melatonin and vitamin d may be good company during covid-19 pandemic (2021) (1)
Morphological basis for polypeptide hormone secretion by pineal gland of Macacus rhesus (Polish) (1975) (1)
Issue Information‐ToC (2021) (1)
Chapter 7 The pineal gland, melatonin, and reproduction (1998) (1)
Adaptations of the Reproductive System of Rodents to Changing Photoperiodic Conditions (1983) (1)
The Multiple Functions of Melatonin: Applications in the Military Setting (2022) (1)
The physiology and pathology of skeletal and cardiac muscle: Beneficial actions of melatonin (2017) (1)
Melatonin: Regulation of Viral Phase Separation and Epitranscriptomics in Post-Acute Sequelae of COVID-19 (2022) (1)
Chapter 5 - The Pineal Gland (1998) (1)
Pineal acid phosphatase activity in Syrian hamsters: sex differences and effects of castration and androgen replacement therapy. (1994) (1)
[The characteristics of melatonin biosynthesis in the epiphysis of relatively wild and domesticated silver foxes Vulpes fulvus]. (1994) (1)
Editorial: Role of Mitochondrial Quality Control in Myocardial and Microvascular Physiology and Pathophysiology (2021) (1)
Inhibition of human chorionic gonadotrophin-induced ovarian and uterine growth in the mouse by synthetic arginine vasotocin (1975) (1)
Melatonin inhibits growth of B16 melanoma in C57BL/6 mice (2020) (1)
Editorial: SIRT Family in Endocrinology (2019) (1)
Evidence that the deep pineal gland of the rat responds to isoproterenol and to swimming stress (1988) (1)
REVIEW - Genetic basis of neurodegeneration in familial Alzheimer's disease. Anna Kowalska . . 171 Synergistic effect of imipramine and amantadine in the forced swimming test in rats. (2004) (1)
Melatonin and Trimetazidine in IGL-1 solution: new insights for fatty liver preservation. (2010) (1)
Advances in Characterizing Recently-Identified Molecular Actions of Melatonin: Clinical Implications (2020) (1)
Acute effects of arginine vasotocin on plasma and pituitary levels of prolactin in the male rat: influence of urethane anesthesia. (1980) (1)
The influence of time of day of administration on the effects of arginine vasotocin (AVT) on reproductive parameters in the female rat and hamster (1980) (1)
Nuclear and cytoplasmic inclusion bodies in pinealocytes of the cotton rat, Sigmodon bispidus: an electron microscopic study. (1984) (1)
Neither prolactin nor growth hormone restore the nocturnal rise in pineal N-acetyltransferase activity or melatonin content in hypophysectomized rats (1988) (1)
[Ca(2+)+Mg2+]-dependent ATPase activity in rat pineal gland. (1993) (1)
Effects of LH manipulations on the castration-induced prophyrin rise in Syrian hamster Harderian glands (1991) (1)
[Melatonin, coronavirus, cardiovascular disease, and the geriatric emergency: let's use everything we have!] (2020) (1)
Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following delta 9-tetrahydrocannabinol administration. (1980) (1)
Abstracts of the 15th Annual Meeting of the Israel Society for Neuroscience Eilat, Israel, December 3–5, 2006 (2006) (1)
Coronavirus-19, Monocyte/Macrophage Glycolysis and Inhibition by Melatonin (2021) (1)
Melatonin and 5-fluorouracil combination chemotherapy: opportunities and efficacy in cancer therapy (2023) (1)
Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm (2023) (1)
The impact of melatonin and carbon ion irradiation on cancer stem cells (2017) (1)
Differential expression and interaction of melatonin and thyroid hormone receptors with estrogen receptor α improve ovarian functions in letrozole-induced rat polycystic ovary syndrome. (2021) (1)
A perspective on the proposed association of melatonin and aging (1998) (1)
cells: implications for osteoblast differentiation and osteoporosis Running title: Melatonin Inhibits TG Accumulation (2007) (1)
Phytomelatonin: A master regulator for plant oxidative stress management. (2023) (1)
Circadian rhythm abnormalities of melatonin and haploinsufficiency of COPS3 in Srnith-Magenis Syndrome (2000) (1)
Author Correction: Melatonin and mitochondrial function during ischemia/reperfusion injury (2018) (1)
Lindane and DDT-lnduced changes in rat harderian N-acetyltransferase activity, melatonin levels, and porphyrin concentration (1995) (1)
Sleep, mortality and beyond: A magician can't pull more from the hat than has been put in earlier. (2017) (1)
Lactacystin-induced kidney fibrosis: Protection by melatonin and captopril (2022) (1)
Rat Serum Melatonin Rise and Fall: Influence of Morning Light, (1993) (1)
Mitochondrial functions and melatonin: a tour of the reproductive cancers (2018) (1)
Characteristics and regulation of N-acetyltransferase activity in the Harderian glands of Syrian hamsters (1991) (1)
Similarities in the Refractoriness of the Reproductive System of Hamsters to Melatonin and to Darkness (1981) (1)
Melatonin and phase separation: potential interactions and significance (2022) (1)
Melatonin inhibits Zika virus replication in Vero epithelial cells and SK-N-SH human neuroblastoma cells (2022) (1)
The proteomic landscape of ovarian cancer cells in response to melatonin. (2022) (1)
Comment on “Diversity Outbred: A New Generation of Mouse Model” (2015) (1)
Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta‐catenin signaling (2022) (1)
Melatonin inhibition of reproduction in pinealectomized male Syrian hamsters: Effects of various hypothalamic cuts (1980) (1)
A 15-minute light pulse during darkness prevents the antigonadotrophic action of afternoon melatonin injections in male hamsters (1982) (1)
Indoleamines and related enzyme contents of the pineal gland of the mule (Equus asinus x Equus caballus) (1986) (1)
Melatonin reduces the mortality of severely-infected COVID-19 patients (2021) (1)
Stimulation of thyroid mitotic activity by intraventricular 6-hydroxydopamine in desmethylimipramine-pretreated rats (1983) (1)
Influence of prolactin on the ultrastructure of the rat pinealocytes in vitro: a quantitative study (1990) (1)
Changes in brain dopamine, norepinephrine and serotonin associated with convulsions induced by pinealectomy in the gerbil (2005) (1)
Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics (2023) (1)
Molecular mechanisms of melatonin’s inhibitory actions on breast cancers (2012) (1)
Photoperiodic control of rat pineal serotonin N-acetyl-transferase activity. (1979) (1)
Inhibition of human chlorionic gonadotrophin-induced ovarian and uterine growth in the mouse by synthetic arginine vasotocin-1. (1975) (1)
Tryptophan Metabolism in the Pineal Gland (1984) (1)
Reversal of pineal antigonadotrophic activity in male hamsters by the administration of pineal indoles (1975) (1)
Mg2+‐dependent and Ca2+, Mg2+‐dependent ATPase activities in the Harderian gland of rodents: Age and sex influences (1996) (1)
Alkylating Agent-Induced Toxicity and Melatonin-Based Therapies (2022) (1)
Growth of the endocrine organs of female hamsters blinded at 25 days of age (2005) (1)
Technique for repeated collection of blood that has just perfused the pineal gland of sheep. (1987) (1)
Dysregulated light/dark cycle impairs sleep and delays the recovery of patients in intensive care units: A call for action for COVID-19 treatment (2022) (1)
Editorial: Extracellular vesicles in cancer immunosurveillance (2022) (1)
The Occurrence of the Biogenic Amine Melatonin in Olive Oil: Implications in Health and Disease Prevention (2010) (1)
Resveratrol is a promising agent for colorectal cancer prevention and treatment: focus on molecular mechanisms (2019) (1)
[Morphological basis for polypeptide hormone secretion by the pineal body of macacus rhesus]. (1975) (1)
Melatonin Attenuates Ischemic-like Cell Injury by Promoting Autophagosome Maturation via the Sirt1/FoxO1/Rab7 Axis in Hippocampal HT22 Cells and in Organotypic Cultures (2022) (0)
New insights into antimetastatic signaling pathways of melatonin in skeletomuscular sarcoma of childhood and adolescence (2020) (0)
Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery (2016) (0)
Melatonin: An anticancer molecule in esophageal squamous cell carcinoma: A mechanistic review (2023) (0)
Letter: The pineal gland: Another perspective. (1975) (0)
Melatonin: Epigenetic mechanisms in cancer inhibition (2011) (0)
Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells (2018) (0)
[abstract] INDIVIDUAL AND INTERACTIVE EFFECTS OF MELATONIN WITH HYPERBARIC OXYGEN ON Cu/Zn-SOD mRNA LEVELS IN LUNG AND BRAIN CORTEX OF RATS. (2008) (0)
Light, Water, and Melatonin: The Synergistic Regulation of Phase Separation in Dementia (2023) (0)
Melatonin, macrophages and microbiota: Interactions (2022) (0)
Antioxidant and antiinflammatory role of melatonin in Alzheimer's neurodegeneration (2020) (0)
Histone deacetylase 9 regulates disease resistance through fine‐tuning histone deacetylation of melatonin biosynthetic genes and melatonin accumulation in cassava (2023) (0)
Melatonin inhibits Gram-negative pathogens by targeting citrate synthase (2022) (0)
Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair (2012) (0)
Covid-19 pandemic and vitamin d deficiency: A different approach with an analysis of the findings and a complimentary proposal (2021) (0)
Therapeutic Applications of Melatonin in Pediatrics (2014) (0)
Nrf2 signaling in diabetic nephropathy, cardiomyopathy and neuropathy: Therapeutic targeting, challenges and future prospective (2023) (0)
Frequency of injection and age of the animal as factors in determining the antigonadotrophic capability of melatonin in Syrian hamsters (1979) (0)
Compensatory growth of the ovaries, adrenal glands and kidneys in blinded, anosmic rats (1972) (0)
Vascular oxidative stress-induced senescence is minimized by melatonin intake in apoe-deficient mice (2011) (0)
Antioxidants and redox-active metals in the epigenetic pathogenesis of cutaneous melanoma: epidemiologic and experimental evidence (2017) (0)
Redefining Autoimmune Disorders’ Pathoetiology: Implications for Mood and Psychotic Disorders’ Association with Neurodegenerative and Classical Autoimmune Disorders (2023) (0)
The pineal hormone melatonin inhibits LPS-induced lipid peroxidationin vitro (1995) (0)
Multidrug nanoformulations of vitamin D, anandamide and melatonin as a synergistic treatment for vascular inflammation. (2023) (0)
Theme: Toward Personalized Breast Cancer Therapy (2011) (0)
Acute effects of arginine vasotocin on plasma prolactin levels in the PMS-treated immature female rat: Influence of urethane anesthesia (1980) (0)
Estrogen-induced uterine metaplasia in rats given oral supplements of vitamin A (1965) (0)
Pharmacology of Melatonin as a Neural Antioxid Ant (1997) (0)
Melatonin: Metabolic consequences and implications for disease prevention (2013) (0)
Melatonin and TGF-β-Mediated Release of Extracellular Vesicles (2023) (0)
Intraventricular 6-hydroxydopamine increases the adrenal cortex mitotic activity in rats. (1984) (0)
Repression of sexual development by short photoperiods or melatonin implants in the white=footed mouse. Peromyscus leucopus (1980) (0)
Type II iodothyronine 5'-deiodinase in mouse brown adipose tissue is stimulated by a single injection of isoproterenol in an oil/water emulsion. (2009) (0)
Factors influential in determining the gonad-inhibiting activity of the pineal gland (2008) (0)
Reproductive Effects of the Pineal Gland and Pineal Indoles in the Syrian Hamster and the Albino Rat (2020) (0)
Melatonin as an antioxidant – a role in human aging? (2008) (0)
Book Review:Neuroendocrinology in Physiology and Medicine P. Michael Conn, Marc E. Freeman (2000) (0)
Melatonin's effectiveness in inducing gonadal quiescence in female hamsters (1979) (0)
Pineal melatonin deprivation alters the mRNA expression of melatonin and steroidogenic-related receptor genes in rat oviduct and uterus during the estrus stage of estrous cycle (2022) (0)
The pineal. Volume 3. (1978) (0)
Pineal Gland and Melatonin (2009) (0)
The altruism of melatonin: A molecule that protects, heals, and even takes care of the night-shift duties (2019) (0)
Editorial: Update on the Endocrinology of Myocardial Aging/Heart Failure (2020) (0)
Chronodisruption: Origin, Roots, and Developments of an 18-Year-Old Concept. Comment on Desmet et al. Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chronic Jetlag. Nutrients 2021, 13, 3846 (2022) (0)
Effects of 60-Hz electric and magnetic fields on operant and social behavior and on neuroendocrine system of nonhuman primates (1992) (0)
[The melatonin content of the tissues of relatively wild and domesticated silver foxes Vulpes fulvus]. (1993) (0)
Epilogue (1994) (0)
Microsoft Word - HRE285BF.rtf (2008) (0)
Phytomelatonin: Improving hardiness, stress tolerance and crop production (2016) (0)
Melatonin oral supplementation against fibromyalgia-related skeletal muscle alterations (2016) (0)
[The mammalian pineal gland: a brief survey of its biosynthetic capabilities and physiologic significance]. (1990) (0)
Melatonin and cancer suppression: insights into its effects on DNA methylation (2022) (0)
Exogenous melatonin increases bile production after cold storage and reperfusion in rat liver. (2003) (0)
Premature inverse ovulation with simulation of a corpus luteum in the white-footed mouse (Peromyscus leucopus) (1982) (0)
Table of Contents, Editor's Choice, Highlights (2018) (0)
The Absence of Pineal Melatonin Abolishes the Daily Rhythm of Tph1 (Tryptophan Hydroxylase 1), Asmt (Acetylserotonin O-Methyltransferase), and Aanat (Aralkylamine N-Acetyltransferase) mRNA Expressions in Rat Testes (2019) (0)
Melatonin mitigates the damaging effects of ionizing radiation. (2008) (0)
Daytime Daytime Daytime Daytime Saline Inj , Melatonin Inj . Saline Inj (2003) (0)
The absence of nuclear uptake of sex steroid hormones in the pineal gland of the baboon (Papio cynocephalus) (1983) (0)
Effect of pargyline, a monoamine oxidase inhibitor, on rat pineal N-acetyltransferase activity (1981) (0)
Comparison of melatonin synthesis in the retina and pineal gland at different times of the year (1994) (0)
oxygenin lung and brain induced by hyperbaric Acutely administered melatonin reduces oxidative (2015) (0)
Regulation of the type II thyroxine-5'-deiodinase circadian rhythm in the rat frontal cerebral cortex (1988) (0)
Melatonin and glutathione reduce lipid peroxidation products in lymphocytes cultured with H2O2 and iron (1996) (0)
57 Role of Nitric Oxide on Oxidative Stress of Newborn. Experimental Study (2005) (0)
Melatonin as a free radical scavenger: implications for experimental medicine (2006) (0)
Interferon- ɤ Modulates Indoleamine Metabolism in Rat Pineal Gland in Organ Culture (1991) (0)
Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model (2021) (0)
Ongoings in the apple watercore: First evidence from proteomic and metabolomic analysis. (2022) (0)
Does melatonin play a role in sexual development in the male rat (1984) (0)
CHANGES IN THE BIOSYNTHETIC CAPABILITIES OF THE PINEAL GLAND DURING AGING (2008) (0)
Comparative radiosensitization efficiency assessment of graphene oxide and Ti3C2 MXene as 2D carbon-based nanoparticles against breast cancer cells: characterization, toxicity and mechanisms (2023) (0)
Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis (2020) (0)
Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways (2017) (0)
Melatonin, where it's been and where it's going: Concluding remarks (1996) (0)
Light, melatonin and aging (2002) (0)
Molecular mechanisms and evolutionary history of phytomelatonin in ﬂowering. (2022) (0)
Editorial: Therapeutic Advances in Melatonin Research (2022) (0)
A comparison of melatonin and α-lipoic acid in the reduction of oxidative stress in L6 rat skeletal muscle cells (2015) (0)
25. Melatonin and aging (2000) (0)
Virus and Autophagy: Enemies or Allies (2018) (0)
Excessive light exposure: Endocrine influences particularly as they relate to cancer initiation and progression (2002) (0)
Synergistic actions of Alpelisib and Melatonin in breast cancer cell lines with PIK3CA gene mutation. (2023) (0)
Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans (2013) (0)
Regulation of Mammalian Pineal Melatonin Production by the Electromagnetic Spectrum (2020) (0)
Melatonin in health and diseases. (2022) (0)
Melatonin and non-small cell lung cancer: new insights into signaling pathways (2019) (0)
A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells (2015) (0)
Analysis and detection of Syrian hamster pineal gland derivatives of [3H] serotonin and melatonin in organ cultures stimulated with norepinephrine (1981) (0)
Apparent absence of influence of melatonin on the circadian rhythm in cell division (1984) (0)
Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue (2023) (0)
Therapeutic effects of melatonin on endometriosis, targeting molecular pathways: Current knowledge and future perspective. (2023) (0)
Effects of a bovine pineal peptidic fraction (E5) on plasma and pituitary levels of LH, FSH and prolactin (1982) (0)
Longitudinal Data Are Needed. (2016) (0)
Nyctohemeral profile of type II thyroxine 5'-deiodinase activity in the pineal and Harderian glands of the swiss mouse (1990) (0)
5 Oxidative Stress of Newborn (2012) (0)
Melatonin as a Potential Approach to Anxiety Treatment (2022) (0)
(AFMK), ATTENUATES ACUTE PANCREATITIS IN THE RAT: IN VIVO AND IN VITRO STUDIES (2016) (0)
[abstract] MELATONIN REDUCES OXIDATIVE STRESS RESULTING FROM HBO EXPOSURE MORE EFFECTIVELY THAN OTHER ENDOGENOUS ANTIOXIDANTS, GLUTATHIONE AND SUPEROXIDE DISMUTASE. (2008) (0)
The effects of melatonin supplementation on inflammatory markers among patients with metabolic syndrome or related disorders: a systematic review and meta-analysis of randomized controlled trials (2018) (0)
Melatonin role preventing steatohepatitis and improving liver transplantation results (2016) (0)
Author Correction: Melatonin and mitochondrial function during ischemia/reperfusion injury (2018) (0)
Melatonin Ameliorates Atherosclerosis by Suppressing S100A9/NF-κB Axis-Mediated Vascular Inflammation (2023) (0)
Manipulations which prevent melatonin administered during the 'critical period' from inducing gonadal involution in hamsters (1977) (0)
Pharmacological studies on melatonin production in the pineal gland of the male Syrian hamster (1981) (0)
Journal of Pineal Research guidelines for authors: Melatonin studies using plants (2022) (0)
Role of melatonin in controlling angiogenesis under physiological and pathological conditions (2019) (0)
Roles of Melatonin in Maintaining Mitochondrial Welfare (2019) (0)
IS MELATONIN SUITABLE FOR INCREASING STEATOTIC GRAFT LIVER PRESERVATION?: 2174 (2010) (0)
The Impact of Melatonin and Ionizing Radiation on Autophagy in Cancer Cells (2020) (0)
Melatonin effect on platelets and coagulation: Implications for a prophylactic indication in COVID-19 (2022) (0)
Reduction of oxidative stress by melatonin: Physiology versus pharmacology (1998) (0)
Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces (2014) (0)
PO9-249 ASSOCIATION OF NOCTURNAL MELATONIN LEVELS TO SERUM MATRIX METALLOPROTEINASE-9 CONCENTRATIONS IN PATIENTS WITH MYOCARDIAL INFARCTION (2007) (0)
Correlation of syrian hamster serum tetraiodothyronine (t4) and triiodothyronine (t3) with testes weight in a natural winter photoperiod (1984) (0)
The Melatonin Receptor: Distribution, Biochemistry, and Pharmacology (2020) (0)
Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: Protective effects of melatonin. (2022) (0)
Neuroendocrinology: An Integrated Approach. By David A Lovejoy. Chichester (United Kingdom) and Hoboken (New Jersey): John Wiley & Sons. $145.00 (hardcover); $60.00 (paper). xiv + 402 p; ill.; index. ISBN: 0–470–84431–0 (hc); 0–470–84432–9 (pb). 2005. (2006) (0)
Abstracts (2012) (0)
Different Patterns in the Histology and Autofluorescence of the Harderian Glands of the Syrian Hamster, Rat, Mouse, Mongolian Gerbil and Guinea Pig (2001) (0)
171 MELATONIN IS A SUITABLE THERAPEUTIC STRATEGY TO PROTECTS STEATOTIC LIVERS IN MAJOR HEPATECTOMY UNDER ISCHEMIA-REFERFUSION: A ROLE FOR ER STRESS AND AUTOPHAGY (2012) (0)
Placental melatonin: Beneficial effects for both the fetus and mother (2013) (0)
Erratum: Melatonin protects against stress-induced gastric lesions by scavenging the hydrocyl radical (Journal of Pineal Research (2000) 29 (143-151)) (2000) (0)
Free Radicals and Antioxidants in Otolaryngology (1996) (0)
Melatonin and Its Synthetic Enzymes in Orbital Glands (2020) (0)
The pineal and its hormones. Proceedings of an international symposium, January 2-9, 1982. (1982) (0)
Effects of O2 and glutathione on rat liver microsomal CCl4 metabolism (1985) (0)
Relationships among the pineal gland, the photoperiod, olfaction and reproduction in female rats. (1969) (0)
277 Correlation Between Cytokines, BDP and Modality of Ventilation in Preterm Newborns: Improvement with Melatonin (2005) (0)
Melatonin: Protection of the Intervertebral Disc (2019) (0)
Effect of melatonin supplementation during in vitro maturation on intracellular ROS levels in porcine oocytes (2014) (0)
Effects of Melatonin Alone or Associated with Acyclovir on the Suppressive Treatment of Recurrent Genital Herpes: A Prospective, Randomized, and Double-Blind Study (2023) (0)
Neuroendocrinology: Quid novi? Reflections and commentary (1990) (0)
EXPOSURE TO NATURAL DECREASING PHOTOPERIOD AND TEMPERATURE CONDITIONS INDUCES A MORE RAPID REPRODUCTIVE INVOLUTION IN INBRED (LSH/SsLak) THAN IN RANDOM BRED (LVG/Lak) FEMALE HAMSTERS (1989) (0)
Melatonin directly scavenges peroxyl and alkoxyl radicals and attenuates metabolic disorders due to diabetes in rats (2007) (0)
Melatonin and ubiquitin: what’s the connection? (2014) (0)
Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms (2019) (0)
Phytomelatonin: Helping plants to survive and to thrive (2016) (0)
Potential Mechanisms of Melatonin in Osteosarcoma and Bone-Related Neoplasms: Updated Review. (2022) (0)
The Effect of Ramadan Fasting and Melatonin Supplementation on Sleep Quality in Male Athletes (2021) (0)
Role of CSF in the transport of melatonin (2002) (0)
Oxidative stress in newborns (2012) (0)
Sleep and cancer incidence: Meta-analyses of 62,177 cases among some 1,300,000 study participants in 12 countries (2016) (0)
Melatonin overcomes MCR-mediated colistin resistance 1 in Gram-negative pathogens 2 3 (2020) (0)
A new promising role of melatonin in promoting tumor necrosis factor toxicity in cancer cells (2009) (0)
Kainate-induced lipid peroxidation in rat brain in vitro is markedly reduced by the endogenous antioxidant melatonin (1995) (0)
Melatonin Reduces Microgravity-Induced Bone Loss: Implications for the Challenges of Long-Term Spaceflight (2021) (0)
BIOLOGICAL RHYTHMS AND ENDOCRINE FUNCTION (1975) (0)
Melatonin receptor-mediated attenuation of excitotoxic cell death in cultured spinal cord slices (2021) (0)
Melatonin targeting non-coding RNAs in cancer: Focus on mechanisms and potential therapeutic targets. (2023) (0)
MP43-13 MELATONIN AND TADALAFIL TREATMENT IMPROVES ERECTILE DYSFUNCTION AFTER SPINAL CORD INJURY IN RATS (2014) (0)
Treatise on Pineal Gland and Melatonin. Haldar C., Singaravel M., Kumar Maitra S. eds. Science Publishers, Enfield, NH, USA, 565 pp, 2002. (2003) (0)
Protective effects of melatonin and structurally-related molecules in reducing membrane rigidity due to lipid peroxidation (2016) (0)
Seasonal reproduction in higher vertebrates. Proceedings of the symposium on the seasonal reproduction of higher vertebrates, held at Richmond, Virginia, USA on 27-30 December 1978. (1980) (0)
Subject Index, Vol. 6, 1975 (2004) (0)
Obesity-associated alterations in cardiac connexin-43 and PKC signaling are attenuated by melatonin and omega-3 fatty acids in female rats (2018) (0)
Subject Index, Vol. 6, 1975 (2004) (0)
Histochemical detection of monoamine oxidase and alcohol dehydrogenase activities in the Syrian hamster Harderian glands: existence of a sexual dimorphism (1989) (0)
Melatonin and stress induced increases in gsh in cultured cells (1996) (0)
Refresher corner Melatonin and cardiac pathophysiology (2009) (0)
Melatonin regulates the neurotransmitter secretion disorder induced by caffeine through the gut-brain axis in zebrafish (Danio rerio) (2019) (0)
Contents, Vol. 6, 1975 (1975) (0)
Contents, Vol. 6, 1975 (1975) (0)
Deficiency of immunoreactive somatostatin (IRS) in the median eminence (ME) Of snell dwarf mice (1984) (0)
Aging and vascular dysfunction: beneficial melatonin effects (2011) (0)
Melatonin as an oncostatic agent: Review of the modulation of tumor microenvironment and overcoming multidrug resistance. (2022) (0)
TRX1 mediates melatonin-induced osteogenic differentiation and the inhibition of osteoporosis (2022) (0)
Melatonin promotes the proliferation of primordial germ cell‐like cells derived from porcine skin‐derived stem cells: A mechanistic analysis (2022) (0)
Effects of melatonin long-term treatment in aging mice (2016) (0)
Dynamic Organization of Endocrine Networks a (1991) (0)
Promotion of liquid-to-solid phase transition of cGAS by Baicalein suppresses lung tumorigenesis (2023) (0)
Corrigendum to “Melatonin enhances astaxanthin accumulation in the green microalga Haematococcus pluvialis by mechanisms possibly related to abiotic stress tolerance” [Algal Res. 33 2018; 256–265] (2022) (0)
Antiviral effect of melatonin on Japanese encephalitis virus infection involves inhibition of neuronal apoptosis and neuroinflammation in SH-SY5Y cells (2023) (0)
[The circadian dynamics of melatonin concentration in the epiphysis, plasma and retina of silver foxes]. (1994) (0)

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