Ruth Chiquet-Ehrismann
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Swiss biochemist and cell biologist
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Ruth Chiquet-Ehrismannbiology Degrees
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Biology
Ruth Chiquet-Ehrismann's Degrees
- PhD Biochemistry University of Basel
- Masters Biochemistry University of Basel
Why Is Ruth Chiquet-Ehrismann Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ruth Chiquet-Ehrismann was a Swiss biochemist and cell biologist working on interactions in the extracellular matrix. Life Ruth Chiquet-Ehrismann was born in Zürich. She received her Ph.D. from the ETH Zürich in 1981. Her mentors were Hans M. Eppenberger and David C. Turner. As a postdoctoral fellow she worked with Robert Dottin at the Johns Hopkins University in Baltimore, US. In 1984 she joined the Friedrich Miescher Institute for Biomedical Research in Basel as a Junior group leader and was promoted to Senior group leader in 1993.
Ruth Chiquet-Ehrismann's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis (1986) (983)
- Tenascin interferes with fibronectin action (1988) (595)
- Tenascins: regulation and putative functions during pathological stress (2003) (514)
- Two contrary functions of tenascin: Dissection of the active sites by recombinant tenascin fragments (1989) (420)
- A Drosophila Neurexin Is Required for Septate Junction and Blood-Nerve Barrier Formation and Function (1996) (420)
- Tenascin: cDNA cloning and induction by TGF‐beta. (1988) (418)
- Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro (1987) (374)
- Tenascin-C induced signaling in cancer. (2006) (346)
- CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis. (2005) (315)
- The Evolution of Extracellular Matrix (2010) (291)
- Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme (1987) (285)
- Tenascin is a stromal marker for epithelial malignancy in the mammary gland. (1987) (274)
- The distribution of tenascin coincides with pathways of neural crest cell migration. (1988) (257)
- Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation. (2001) (251)
- The extracellular matrix ligands fibronectin and tenascin collaborate in regulating collagenase gene expression in fibroblasts. (1994) (236)
- What distinguishes tenascin from fibronectin? (1990) (226)
- Syndecan from embryonic tooth mesenchyme binds tenascin. (1989) (205)
- Epithelial induction of stromal tenascin in the mouse mammary gland: from embryogenesis to carcinogenesis. (1988) (204)
- Tenascins and the importance of adhesion modulation. (2011) (201)
- Regulation of extracellular matrix synthesis by mechanical stress. (1996) (198)
- Tenascin-C expression by fibroblasts is elevated in stressed collagen gels (1994) (190)
- The discoidin domain family revisited: New members from prokaryotes and a homology‐based fold prediction (1998) (187)
- Changes in the distribution of tenascin during tooth development. (1987) (187)
- Tenm, a Drosophila gene related to tenascin, is a new pair‐rule gene. (1994) (173)
- Tenascin, an extracellular matrix protein, exerts immunomodulatory activities. (1989) (172)
- Anti-adhesive molecules of the extracellular matrix. (1991) (172)
- Connective tissues: signalling by tenascins. (2004) (162)
- Participation of tenascin and transforming growth factor-beta in reciprocal epithelial-mesenchymal interactions of MCF7 cells and fibroblasts. (1989) (161)
- The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C (1994) (161)
- Tenascin variants: differential binding to fibronectin and distinct distribution in cell cultures and tissues. (1991) (153)
- The effect of tenascin and embryonic basal lamina on the behavior and morphology of neural crest cells in vitro. (1989) (146)
- Restrictin: a chick neural extracellular matrix protein involved in cell attachment co-purifies with the cell recognition molecule F11. (1991) (145)
- Tenascins in stem cell niches. (2014) (141)
- Teneurins: a conserved family of transmembrane proteins involved in intercellular signaling during development. (2006) (139)
- Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. (2009) (132)
- wing blister, A New Drosophila Laminin α Chain Required for Cell Adhesion and Migration during Embryonic and Imaginal Development (1999) (130)
- Mouse Ten-m/Odz Is a New Family of Dimeric Type II Transmembrane Proteins Expressed in Many Tissues (1999) (122)
- The high-molecular-weight J1 glycoproteins are immunochemically related to tenascin. (1988) (117)
- The regulation of tenascin expression by tissue microenvironments. (2009) (113)
- Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis. (2010) (111)
- Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. (1999) (108)
- Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor. (2015) (105)
- The tenascin gene family. (1994) (105)
- The complexity in regulating the expression of tenascins (1995) (102)
- Tenascin and other adhesion-modulating proteins in cancer. (1993) (102)
- The Fibrinogen-like Globe of Tenascin-C Mediates Its Interactions with Neurocan and Phosphacan/Protein-tyrosine Phosphatase-ζ/β* (1997) (99)
- Tenascin-Y: a protein of novel domain structure is secreted by differentiated fibroblasts of muscle connective tissue (1996) (97)
- Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage (2006) (97)
- Teneurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene product Ten-m. (1999) (95)
- Collagen XII Interacts with Avian Tenascin-X through Its NC3 Domain* (2006) (93)
- Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro (2005) (93)
- Tena , a Drosophila gene related to tenascin, shows selective transcript localization (1993) (92)
- Differential Gene Expression Analysis Reveals Activation of Growth Promoting Signaling Pathways by Tenascin-C (2004) (90)
- The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription (2003) (89)
- Tenascin-C: Its functions as an integrin ligand. (2015) (85)
- Phylogenetic Analysis of the Teneurins: Conserved Features and Premetazoan Ancestry (2011) (84)
- Tenascin-C blocks cell-cycle progression of anchorage-dependent fibroblasts on fibronectin through inhibition of syndecan-4 (2003) (82)
- Adhesion modulation by antiadhesive molecules of the extracellular matrix. (2000) (82)
- Tenascins, a growing family of extracellular matrix proteins (1995) (81)
- Tenascin expression in the human endometrium and in endometrial adenocarcinomas. (1990) (81)
- Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development (2004) (81)
- CCN4/WISP1 (WNT1 inducible signaling pathway protein 1): a focus on its role in cancer. (2015) (79)
- Concerted action of tenascin-C domains in cell adhesion, anti-adhesion and promotion of neurite outgrowth. (1997) (77)
- Transcriptional regulation of tenascin genes (2015) (74)
- Tenascin-W is a novel marker for activated tumor stroma in low-grade human breast cancer and influences cell behavior. (2007) (71)
- Cell-adhesive responses to tenascin-C splice variants involve formation of fascin microspikes. (1997) (71)
- Regulation of Integrin α5β1 Affinity during Myogenic Differentiation (1995) (71)
- ten-1, an essential gene for germ cell development, epidermal morphogenesis, gonad migration, and neuronal pathfinding in Caenorhabditis elegans. (2005) (68)
- The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. (2005) (68)
- ‘Perineuronal nets’ around cortical interneurons expressing parvalbumin are rich in tenascin (1993) (68)
- Phylogenetic analysis of teneurin genes and comparison to the rearrangement hot spot elements of E. coli. (2000) (68)
- Tenascin‐C in serum: A questionable tumor marker (1995) (67)
- Teneurin 2 is expressed by the neurons of the thalamofugal visual system in situ and promotes homophilic cell-cell adhesion in vitro. (2002) (67)
- The fibrinogen globe of tenascin-C promotes basic fibroblast growth factor-induced endothelial cell elongation. (1999) (66)
- Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion. (1994) (66)
- Teneurin-1 is expressed in interconnected regions of the developing brain and is processed in vivo (2008) (66)
- TGF-&bgr;-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms (2014) (64)
- Isolation of chick tenascin variants and fragments. A C-terminal heparin-binding fragment produced by cleavage of the extra domain from the largest subunit splicing variant. (1991) (62)
- Evidence for the evolution of tenascin and fibronectin early in the chordate lineage. (2009) (61)
- Growth promoting signaling by tenascin-C [corrected]. (2004) (61)
- Deciphering teneurin domains that facilitate cellular recognition, cell-cell adhesion, and neurite outgrowth using atomic force microscopy-based single-cell force spectroscopy. (2013) (60)
- The transcriptional regulator megakaryoblastic leukemia‐1 mediates serum response factor‐independent activation of tenascin‐C transcription by mechanical stress (2011) (59)
- Teneurin‐2 is expressed in tissues that regulate limb and somite pattern formation and is induced in vitro and in situ by FGF8 (2001) (59)
- Dermal fibroblast-derived growth factors restore the ability of beta(1) integrin-deficient embryonal stem cells to differentiate into keratinocytes. (2001) (57)
- Tenascin gene expression in rat liver and in rat liver cells In vivo and in vitro studies (1991) (57)
- Inhibition of cell adhesion by anti-adhesive molecules. (1995) (55)
- Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro (2010) (55)
- A Single Heparin Binding Region within the Fibrinogen-like Domain Is Functional in Chick Tenascin-C (*) (1995) (53)
- Tenascin‐W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients (2008) (53)
- Teneurins: transmembrane proteins with fundamental roles in development. (2007) (52)
- Megakaryoblastic leukemia protein-1 (MKL1): Increasing evidence for an involvement in cancer progression and metastasis. (2010) (51)
- Tenascin-C signaling through induction of 14-3-3 tau (2003) (49)
- SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients (2014) (49)
- Caenorhabditis elegans teneurin, ten-1, is required for gonadal and pharyngeal basement membrane integrity and acts redundantly with integrin ina-1 and dystroglycan dgn-1. (2008) (48)
- Tenascins and their implications in diseases and tissue mechanics (2009) (48)
- Immunohistochemical localization of the matrix glycoprotein tenascin in the skull of the growing rat. (1988) (47)
- The evolution of tenascins and fibronectin (2015) (47)
- In situ localization of thrombospondin‐1 and thrombospondin‐3 transcripts in the avian embryo (1997) (47)
- Teneurins, a transmembrane protein family involved in cell communication during neuronal development (2007) (46)
- ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis (2010) (44)
- The expression of tenascin-C with the AD1 variable repeat in embryonic tissues, cell lines and tumors in various vertebrate species. (1997) (43)
- Novel tenascin variants with a distinctive pattern of expression in the avian embryo. (1994) (42)
- The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis. (1995) (42)
- Increased expression of tenascin in the dermis in scleroderma (1992) (41)
- SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors. (2011) (41)
- CD 24 Expression Causes the Acquisition of Multiple Cellular Properties Associated with Tumor Growth and Metastasis (2005) (41)
- Tenascin-C is required for normal Wnt/β-catenin signaling in the whisker follicle stem cell niche. (2014) (37)
- Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts. (1996) (36)
- How do tenascins influence the birth and life of a malignant cell? (2011) (34)
- Thrombospondin‐1 and neural crest cell migration (1999) (34)
- Biodistribution of 111In‐labelled SCN‐bz‐DTPA‐BC‐2 MAb following loco‐regional injection into glioblastomas (1997) (33)
- The expression of teneurin-4 in the avian embryo (2000) (32)
- Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors (2012) (32)
- Expression patterns of two new members of the Semaphorin family in Drosophila suggest early functions during embryogenesis (2000) (32)
- TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms (2014) (31)
- The human placenta: a model for tenascin expression (2004) (30)
- Transcriptional regulation of tenascin‐W by TGF‐beta signaling in the bone metastatic niche of breast cancer cells (2015) (30)
- Differential expression of tenascin splicing variants in the chick gizzard and in cell cultures. (1990) (29)
- Avian tenascin‐W: Expression in smooth muscle and bone, and effects on calvarial cell spreading and adhesion in vitro (2006) (29)
- Regulation of integrin alpha 5 beta 1 affinity during myogenic differentiation. (1995) (27)
- The Intracellular Domain of Teneurin-1 Induces the Activity of Microphthalmia-associated Transcription Factor (MITF) by Binding to Transcriptional Repressor HINT1 (2015) (27)
- Expression in Fibroblasts (2003) (26)
- C. elegans Agrin Is Expressed in Pharynx, IL1 Neurons and Distal Tip Cells and Does Not Genetically Interact with Genes Involved in Synaptogenesis or Muscle Function (2007) (26)
- The expression of teneurin-4 in the avian embryo: potential roles in patterning of the limb and nervous system. (2010) (24)
- Effects of tenascin-W on osteoblasts in vitro (2008) (24)
- Identification and characterization of a dimeric chicken fibronectin receptor. Subunit-specific monoclonal antibodies to the putative chicken alpha 5 beta 1 integrin. (1990) (24)
- Dermo‐epidermal separation is associated with induced tenascin expression in human skin (1995) (23)
- The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis (2013) (23)
- Tenascin‐C triggers fibrin accumulation by downregulation of tissue plasminogen activator (2011) (22)
- Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration (2013) (22)
- Tenascin-W: an extracellular matrix protein associated with osteogenesis and cancer. (2010) (21)
- Tenascin-Y, a component of distinctive connective tissues, supports muscle cell growth. (1999) (20)
- Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV–mediated basement membrane integrity during late elongation of the embryo (2011) (19)
- Rapid increase in plasma tenascin‐C concentration after isolated limb perfusion with high‐dose tumor necrosis factor (TNF), interferon gamma (IFNγ) and melphalan for regionally advanced tumors (1995) (18)
- Mechanism of irradiation‐induced mammary cancer metastasis: A role for SAP‐dependent Mkl1 signaling (2015) (18)
- Tenascin function and regulation of expression. (1993) (18)
- Tenascin‐C induced stimulation of chondrogenesis is dependent on the presence of the C‐terminal fibrinogen‐like globular domain (2000) (18)
- Structural Motifs of the Extracellular Matrix Proteins Laminin and Tenascin (1992) (17)
- The Adhesion Modulating Properties of Tenascin-W (2011) (17)
- Immunohistochemical study of the heterogeneity of tenascin distribution within the oral mucosa of the mouse. (1990) (17)
- A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis * (2018) (16)
- Opposite effect of fluticasone and salmeterol on fibronectin and tenascin‐C expression in primary human lung fibroblasts (2009) (16)
- Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter (2011) (15)
- Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling (2018) (15)
- KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist (2016) (15)
- Tenascin-Y in the Developing and Adult Avian Nervous System (1999) (15)
- Evidence for transcriptional repression of SPARC-like 1, a gene downregulated in human lung tumors. (2004) (14)
- Drosophila ribosomal protein S19 cDNA sequence. (1993) (12)
- Tenascin‐Y is concentrated in adult nerve roots and has barrier properties in vitro (2001) (12)
- Immunocytochemical localisation of tenascin during the development of scleral papillae and scleral ossicles in the embryonic chick. (1988) (10)
- Role of tenascin in cancer development. (1998) (10)
- A selective extracellular matrix proteomics approach identifies fibronectin proteolysis by ADAMTS16 and its impact on spheroid morphogenesis (2018) (10)
- Changes in the cellular phenotype and extracellular matrix during progression of estrogen-induced mesenchymal kidney tumors in Syrian hamsters (1991) (10)
- Novel Human Tenascin-C Function-Blocking Camel Single Domain Nanobodies (2021) (10)
- Tenascin-C is associated with cored amyloid-β plaques in Alzheimer disease and pathology burdened cognitively normal elderly (2016) (9)
- The teneurin C-terminal domain possesses nuclease activity and is apoptogenic (2018) (9)
- Lactogenic hormones and Tenascin‐C regulate C/EBPα and β in mammary epithelial cells (2000) (8)
- Sex-dependent expression of tenascin-C in the differentiating fetal rat testis and ovary. (1995) (8)
- Pivotal Role of Tenascin-W (-N) in Postnatal Incisor Growth and Periodontal Ligament Remodeling (2021) (7)
- Generation and characterization of dromedary Tenascin-C and Tenascin-W specific antibodies. (2020) (5)
- Lactogenic hormones and tenascin-C regulate C/EBPalpha and beta in mammary epithelial cells. (2000) (3)
- Tenascin variants: ligands and expression. (1993) (2)
- The expression of tenascin‐C and tenascin‐W in human ossicles (2016) (2)
- Tenascin-W Is a Novel Stromal Marker in Biliary Tract Cancers (2021) (2)
- Function of Tenascins in the Tumor Stroma (2011) (1)
- SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients (2014) (1)
- TNC (tenascin C (hexabrachion)) (2011) (1)
- Introduction: Brain extracellular matrix—a neglected component of the central nervous system (1996) (1)
- Preparation and Application of a Decellularized Extracellular Matrix for Identification of ADAMTS Substrates. (2020) (1)
- Properties Associated with Tumor Growth and Metastasis CD 24 Expression Causes the Acquisition of Multiple Cellular (2005) (0)
- Cloning of the Drosophila homologue of tenascin (1990) (0)
- Fibroblasts Reciprocal Epithelial-Mesenchymal Interactions of MCF 7 Cells in β Participation of Tenascin and Transforming Growth Factor-Updated (2006) (0)
- Does tenascin affect integrin function (1990) (0)
- Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling (2018) (0)
- Program/Abstract # 426The roles of tenascin-W in osteogenesis (2007) (0)
- Teneurin-1 ICD as a transcriptional regulator The intracellular domain of teneurin-1 induces the activity of transcription factor MITF by binding to transcriptional repressor HINT 1 (2015) (0)
- PERSPECTIVES The Evolution of Extracellular Matrix (2010) (0)
- Table of Contents (1994) (0)
- Functional Domains of Tenascin (1989) (0)
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