Ruth M. Mcpherson
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Ruth M. Mcpherson's Degrees
- PhD Genetics University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Ruth M. Mcpherson Influential?
(Suggest an Edit or Addition)Ruth M. Mcpherson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
- A Common Allele on Chromosome 9 Associated with Coronary Heart Disease (2007) (1497)
- New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
- Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol (2004) (1118)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- Loss-of-function mutations in APOC3, triglycerides, and coronary disease. (2014) (799)
- 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations. (2009) (789)
- 2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. (2013) (756)
- 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult. (2016) (734)
- The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group. (1998) (668)
- Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. (2016) (630)
- Meta-analysis and imputation refines the association of 15q25 with smoking quantity (2010) (605)
- A decision aid for women considering hormone therapy after menopause: decision support framework and evaluation. (1998) (564)
- A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium (2009) (551)
- Association analyses based on false discovery rate implicate new loci for coronary artery disease (2017) (476)
- Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
- Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease (2010) (417)
- Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus (2009) (401)
- A structural variation reference for medical and population genetics (2020) (394)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Genetics of Coronary Artery Disease. (2016) (363)
- Recommendations for the management of dyslipidemia and the prevention of cardiovascular disease: summary of the 2003 update. (2003) (362)
- LDL-cholesterol concentrations: a genome-wide association study (2008) (355)
- Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population (2014) (348)
- Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD (2011) (342)
- Canadian Cardiovascular Society position statement--recommendations for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease. (2006) (336)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (309)
- Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants (2014) (303)
- Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. (2014) (292)
- Inactivating mutations in NPC1L1 and protection from coronary heart disease. (2014) (289)
- Lipid Treatment Assessment Project 2: A Multinational Survey to Evaluate the Proportion of Patients Achieving Low-Density Lipoprotein Cholesterol Goals (2009) (279)
- Randomized Trial of a Portable, Self-administered Decision Aid for Postmenopausal Women Considering Long-term Preventive Hormone Therapy (1998) (244)
- Dysfunctional nitric oxide signalling increases risk of myocardial infarction (2013) (234)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Medical sequencing at the extremes of human body mass. (2006) (228)
- Distribution and concentration of cholesteryl ester transfer protein in plasma of normolipemic subjects. (1990) (227)
- Plasma concentrations of cholesteryl ester transfer protein in hyperlipoproteinemia. Relation to cholesteryl ester transfer protein activity and other lipoprotein variables. (1991) (226)
- Low copy number of the salivary amylase gene predisposes to obesity (2014) (224)
- Genetically determined height and coronary artery disease. (2015) (220)
- Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells (2011) (215)
- Triglycerides and Heart Disease: Still a Hypothesis? (2011) (206)
- Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (2017) (204)
- Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
- Disruption at the PTCHD1 Locus on Xp22.11 in Autism Spectrum Disorder and Intellectual Disability (2010) (193)
- Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease (2014) (187)
- Meta-Analysis of Gene Level Tests for Rare Variant Association (2013) (183)
- Long-term efficacy and safety of fenofibrate and a statin in the treatment of combined hyperlipidemia. (1998) (182)
- Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. (2011) (177)
- Acylcarnitines: potential implications for skeletal muscle insulin resistance (2015) (170)
- Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. (2016) (164)
- A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels (2009) (164)
- Cardiometabolic risk in Canada: a detailed analysis and position paper by the cardiometabolic risk working group. (2011) (161)
- Gene dosage of the common variant 9p21 predicts severity of coronary artery disease. (2010) (160)
- Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk (2012) (154)
- A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease (2013) (148)
- 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult. (2021) (148)
- Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction (2014) (147)
- Comparative effects of rosuvastatin and atorvastatin across their dose ranges in patients with hypercholesterolemia and without active arterial disease. (2003) (140)
- Genome‐wide Linkage and Association Analyses to Identify Genes Influencing Adiponectin Levels: The GEMS Stud (2009) (139)
- Prognostic and Therapeutic Implications of Statin and Aspirin Therapy in Individuals With Nonobstructive Coronary Artery Disease: Results From the CONFIRM (Coronary CT Angiography Evaluation For Clinical Outcomes: An International Multicenter Registry) Registry (2015) (136)
- Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease (2017) (135)
- A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex (2012) (131)
- Lack of MEF2A mutations in coronary artery disease. (2005) (127)
- Exome Aggregation Consortium (2016) (125)
- Decreased mitochondrial proton leak and reduced expression of uncoupling protein 3 in skeletal muscle of obese diet-resistant women. (2002) (125)
- Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. (2009) (125)
- High frequency of mutations in the human lipoprotein lipase gene in pregnancy-induced chylomicronemia: possible association with apolipoprotein E2 isoform. (1994) (121)
- Cholesteryl ester transfer protein and high density lipoprotein responses to cholesterol feeding in men: relationship to apolipoprotein E genotype. (1993) (120)
- Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity (2014) (120)
- Effect of postmenopausal estrogen replacement on plasma Lp(a) lipoprotein concentrations. (1994) (118)
- Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis. (2004) (116)
- Improved Prediction of Cardiovascular Disease Based on a Panel of Single Nucleotide Polymorphisms Identified Through Genome-Wide Association Studies (2010) (113)
- Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine (2014) (109)
- Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
- Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. (2012) (99)
- Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia (2013) (98)
- Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease (2016) (97)
- Increase in plasma cholesteryl ester transfer protein during probucol treatment. Relation to changes in high density lipoprotein composition. (1991) (96)
- Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia. (1994) (92)
- Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study. (2009) (91)
- A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2019) (90)
- Transcript expression-aware annotation improves rare variant interpretation (2020) (89)
- Comparative effects of 10-mg versus 80-mg Atorvastatin on high-sensitivity C-reactive protein in patients with stable coronary artery disease: results of the CAP (Comparative Atorvastatin Pleiotropic effects) study. (2008) (87)
- Vascular Calcifications in Homozygote Familial Hypercholesterolemia (2008) (87)
- Evaluating drug targets through human loss-of-function genetic variation (2019) (86)
- Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals (2015) (84)
- The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential (2019) (84)
- Cathepsin D, a Lysosomal Protease, Regulates ABCA1-mediated Lipid Efflux* (2006) (82)
- Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). (2005) (81)
- Gain-of-Function R225W Mutation in Human AMPKγ3 Causing Increased Glycogen and Decreased Triglyceride in Skeletal Muscle (2007) (81)
- Adipocyte Low Density Lipoprotein Receptor-related Protein Gene Expression and Function Is Regulated by Peroxisome Proliferator-activated Receptor γ* (2003) (78)
- Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2019) (78)
- Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. (2017) (77)
- Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk (2013) (75)
- Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary). (2011) (70)
- Gene expression profiling in whole blood identifies distinct biological pathways associated with obesity (2010) (70)
- Chromosome 9p21 and coronary artery disease. (2010) (70)
- Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling (2018) (70)
- The Low Density Lipoprotein Receptor-related Protein Contributes to Selective Uptake of High Density Lipoprotein Cholesteryl Esters by SW872 Liposarcoma Cells and Primary Human Adipocytes* (2001) (70)
- Nonstatin Low-Density Lipoprotein–Lowering Therapy and Cardiovascular Risk Reduction—Statement From ATVB Council (2015) (70)
- The effect of LRRK2 loss-of-function variants in humans (2020) (69)
- Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease (2015) (68)
- Cholesteryl ester transfer protein (CETP) mRNA abundance in human adipose tissue: relationship to cell size and membrane cholesterol content. (1995) (67)
- Endocytosis Is Enhanced in Tangier Fibroblasts (2001) (66)
- Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease (2017) (64)
- Clinical and Genetic Association of Serum Ceruloplasmin With Cardiovascular Risk (2012) (64)
- Genetic analysis for a shared biological basis between migraine and coronary artery disease (2015) (64)
- Cholesteryl Ester Transfer Protein (CETP) Expression Protects Against Diet Induced Atherosclerosis in SR-BI Deficient Mice (2007) (62)
- Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity (2010) (61)
- Cholesteryl Ester Transfer Protein Directly Mediates Selective Uptake of High Density Lipoprotein Cholesteryl Esters by the Liver (2005) (61)
- IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis. (2015) (61)
- Peroxisome Proliferator‐activated Receptor γ 2 and Acyl‐CoA Synthetase 5 Polymorphisms Influence Diet Response (2007) (61)
- Dissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses (2015) (61)
- Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity (2005) (60)
- Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. (1999) (59)
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (59)
- Genetic Etiology of Isolated Low HDL Syndrome: Incidence and Heterogeneity of Efflux Defects (2007) (58)
- Rationale for and outline of the recommendations of the Working Group on Hypercholesterolemia and Other Dyslipidemias: interim report. Dyslipidemia Working Group of Health Canada. (1998) (58)
- ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. (2010) (58)
- Cholesteryl Ester Transfer Protein Mediates Selective Uptake of High Density Lipoprotein Cholesteryl Esters by Human Adipose Tissue* (1997) (56)
- Prevalence of dyslipidemia in statin-treated patients in Canada: results of the DYSlipidemia International Study (DYSIS). (2010) (53)
- Secretory Vesicular Transport from the Golgi Is Altered during ATP-binding Cassette Protein A1 (ABCA1)-mediated Cholesterol Efflux* (2003) (53)
- Relationship of adipose tissue cholesteryl ester transfer protein (CETP) mRNA to plasma concentrations of CETP in man. (1998) (50)
- Discordance between Framingham Risk Score and atherosclerotic plaque burden. (2013) (49)
- Statin therapy in Canadian patients with hypercholesterolemia: the Canadian Lipid Study -- Observational (CALIPSO). (2005) (47)
- Inflammation and coronary artery disease: insights from genetic studies. (2012) (47)
- Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease (2019) (46)
- A prospective randomized evaluation of a pharmacogenomic approach to antiplatelet therapy among patients with ST-elevation myocardial infarction: the RAPID STEMI study (2015) (45)
- Adipose tissue cholesteryl ester transfer protein mRNA in response to probucol treatment: cholesterol and species dependence. (1993) (44)
- Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of Cardiometabolic phenotypes. (2019) (44)
- Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemias⃞s⃞ The online version of this article (available at http://www.jlr.org) contains an additional four figures. Published, JLR Papers in Press, August 1, 2005. DOI 10.1194/j (2005) (43)
- Cholesteryl ester transfer protein gene expression during differentiation of human preadipocytes to adipocytes in primary culture. (1999) (43)
- Plasma cholesteryl ester transfer protein concentration, high-density lipoprotein cholesterol esterification and transfer rates to lighter density lipoproteins in the fasting state and after a test meal are similar in Type II diabetics and normal controls. (1996) (42)
- Predominance of a Proinflammatory Phenotype in Monocyte-Derived Macrophages From Subjects With Low Plasma HDL-Cholesterol (2007) (41)
- Diet and waist-to-hip ratio: important predictors of lipoprotein levels in sedentary and active young men with no evidence of cardiovascular disease. (1999) (41)
- Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions (2017) (41)
- Identifying genes for coronary artery disease: An idea whose time has come. (2007) (40)
- Association of exome sequences with plasma C-reactive protein levels in >9000 participants. (2015) (40)
- Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. (2016) (39)
- Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease (2016) (39)
- Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat. (1997) (39)
- Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes Published, JLR Papers in Press, July 1, 2004. DOI 10.1194/jlr.M400051-JLR200 (2004) (37)
- Redundancy control in pathway databases (ReCiPa): an application for improving gene-set enrichment analysis in Omics studies and "Big data" biology. (2013) (37)
- Endothelial Gata5 transcription factor regulates blood pressure (2015) (36)
- A PYY Q62P variant linked to human obesity. (2006) (36)
- Whole-Gene Duplication of PCSK9 as a Novel Genetic Mechanism for Severe Familial Hypercholesterolemia. (2018) (36)
- A Novel Efflux–Recapture Process Underlies the Mechanism of High-Density Lipoprotein Cholesteryl Ester-Selective Uptake Mediated by the Low-Density Lipoprotein Receptor–Related Protein (2004) (36)
- Gene–environment interaction in dyslipidemia (2015) (36)
- Functional interaction between COL4A1/COL4A2 and SMAD3 risk loci for coronary artery disease. (2015) (35)
- Genetic contributors to obesity. (2007) (35)
- Early effects of statin therapy on endothelial function and microvascular reactivity in patients with coronary artery disease. (2005) (35)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (34)
- Hepatic SR-BI-mediated cholesteryl ester selective uptake occurs with unaltered efficiency in the absence of cellular energy Published, JLR Papers in Press, December 7, 2005. (2006) (34)
- Recommendations for the Management of Dyslipidemia and the Prevention of Cardiovascular Disease: 200 (2003) (33)
- Factors affecting weight loss variability in obesity. (2020) (33)
- Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages. (2015) (32)
- Obesity shows preserved plasma proteome in large independent clinical cohorts (2018) (32)
- SR-BI Undergoes Cholesterol-stimulated Transcytosis to the Bile Canaliculus in Polarized WIF-B Cells* (2007) (32)
- Comparison of the short-term efficacy and tolerability of lovastatin and pravastatin in the management of primary hypercholesterolemia. (1992) (32)
- Plasma cholesteryl ester synthesis, cholesteryl ester transfer protein concentration and activity in hypercholesterolemic women: effects of the degree of saturation of dietary fatty acids in the fasting and postprandial states. (1996) (31)
- Remnant cholesterol: "Non-(HDL-C + LDL-C)" as a coronary artery disease risk factor. (2013) (31)
- Effects of lovastatin on natural killer cell function and other immunological parameters in man (1993) (30)
- Are the ACC/AHA guidelines on the treatment of blood cholesterol a game changer? A perspective from the Canadian Cardiovascular Society Dyslipidemia Panel. (2014) (30)
- Plasma kinetics of cholesteryl ester transfer protein in the rabbit. Effects of dietary cholesterol. (1997) (29)
- Partitioning the heritability of coronary artery disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity (2017) (28)
- Increased susceptibility to oxidative damage in post-diabetic human myotubes (2009) (28)
- Allelic variation in the gene encoding the cholesteryl ester transfer protein is associated with variation in the plasma concentrations of cholesteryl ester transfer protein. (1996) (28)
- Implications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesity (2013) (28)
- Novel N-terminal mutation of human apolipoprotein A-I reduces self-association and impairs LCAT activation[S] (2011) (27)
- RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (26)
- Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. (2015) (26)
- No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis (2016) (25)
- Two Chromosome 9p21 Haplotype Blocks Distinguish Between Coronary Artery Disease and Myocardial Infarction Risk (2013) (25)
- UCP3 and its putative function: consistencies and controversies. (2001) (25)
- Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study. (2008) (25)
- Lipid screening to prevent coronary artery disease: a quantitative evaluation of evolving guidelines. (2000) (24)
- Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)γ3 results in increased oxidative capacity and glucose uptake in human primary myotubes (2010) (24)
- Blood Gene Expression Reveal Pathway Differences Between Diet‐Sensitive and Resistant Obese Subjects Prior to Caloric Restriction (2011) (23)
- Impact of Selection Bias on Estimation of Subsequent Event Risk (2017) (23)
- Efficacy of atorvastatin in achieving National Cholesterol Education Program low-density lipoprotein targets in women with severe dyslipidemia and cardiovascular disease or risk factors for cardiovascular disease: The Women's Atorvastatin Trial on Cholesterol (WATCH). (2001) (23)
- Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease (2014) (23)
- Role of cholesteryl ester transfer protein in reverse cholesterol transport (1991) (23)
- Role of Lp A-I and Lp A-I/A-II in cholesteryl ester transfer protein-mediated neutral lipid transfer. Studies in normal subjects and in hypertriglyceridemic patients before and after fenofibrate therapy. (1996) (23)
- Increased proton leak and SOD2 expression in myotubes from obese non-diabetic subjects with a family history of type 2 diabetes. (2013) (22)
- Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events (2019) (21)
- From genome-wide association studies to functional genomics: new insights into cardiovascular disease. (2013) (21)
- DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes (2018) (21)
- The metabolic syndrome and type 2 diabetes: role of the adipocyte (2003) (20)
- The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank Studies (2009) (20)
- ADIPOSITY SIGNIFICANTLY MODIFIES GENETIC RISK FOR DYSLIPIDEMIA (2014) (20)
- Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
- Scavenger receptor class B type I localizes to a late endosomal compartment These studies were supported by a grant from the Canadian Institutes for Health Research (CIHR) (to R.M.). Published, JLR Papers in Press, March 29, 2008. (2008) (19)
- TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha (2017) (19)
- The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts (2009) (19)
- Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits (2016) (18)
- TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways (2016) (18)
- Regulation of MFGE8 by the intergenic coronary artery disease locus on 15q26.1. (2019) (18)
- Lower mitochondrial proton leak and decreased glutathione redox in primary muscle cells of obese diet-resistant versus diet-sensitive humans. (2014) (18)
- Preferential expression of cholesteryl ester transfer protein mRNA by stromal-vascular cells of human adipose tissue. (1998) (17)
- ERK1/2 regulates hepatocyte Trib1 in response to mitochondrial dysfunction. (2013) (17)
- Role of Tribbles Pseudokinase 1 (TRIB1) in human hepatocyte metabolism. (2016) (17)
- Partitioning the Pleiotropy Between Coronary Artery Disease and Body Mass Index Reveals the Importance of Low Frequency Variants and Central Nervous System–Specific Functional Elements (2018) (17)
- Genome-Wide Association Studies of Cardiovascular Disease in European and Non-European Populations (2014) (17)
- Increased genetic risk for obesity in premature coronary artery disease (2015) (16)
- Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism (2017) (16)
- Ezetimibe: rescued by randomization (clinical and mendelian). (2015) (16)
- Subsequent Event Risk in Individuals With Established Coronary Heart Disease (2019) (14)
- ERRγ Regulates Cardiac, Gastric, and Renal Potassium Homeostasis. (2009) (14)
- A common biological basis of obesity and nicotine addiction (2019) (14)
- Clinical and public health assessment of benefits and risks of statins in primary prevention of coronary events: resolved and unresolved issues. (2008) (14)
- Adiposity significantly modifies genetic risk for dyslipidemia[S] (2014) (14)
- Is hormone replacement therapy cardioprotective? Decision-making after the heart and estrogen/progestin replacement study. (2000) (14)
- Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: a one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness. (2001) (14)
- Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. (2011) (13)
- Chromosome 9p21.3 locus for coronary artery disease: how little we know. (2013) (13)
- Comparative effects of simvastatin and cholestyramine on plasma lipoproteins and CETP in humans. (1999) (13)
- Severe Hypoalphalipoproteinemia in Mice Expressing Human Hepatic Lipase Deficient in Binding to Heparan Sulfate Proteoglycan* (2004) (12)
- A gene-centric approach to elucidating cardiovascular risk. (2009) (12)
- Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans (2010) (12)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease. (2020) (11)
- Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease (2020) (11)
- A pharmacodynamic comparison of a personalized strategy for anti-platelet therapy versus ticagrelor in achieving a therapeutic window. (2015) (10)
- 2018 George Lyman Duff Memorial Lecture (2019) (10)
- A 680 kb duplication at the FTO locus in a kindred with obesity and a distinct body fat distribution (2013) (10)
- Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
- Statin therapy and the management of acute coronary syndromes. (2003) (9)
- Association of Factor V Leiden With Subsequent Atherothrombotic Events (2020) (8)
- Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
- Coronary artery disease and women: applying the guidelines for risk factor management. (2000) (8)
- Position Statement Cardiometabolic Risk in Canada: A Detailed Analysis and Position Paper by the Cardiometabolic Risk Working Group Cardiometabolic Risk Working Group: Executive Committee: (2011) (7)
- Obesity and ischemic heart disease: defining the link. (2015) (7)
- Is Type 2 Diabetes in Adults Associated With Impaired Capacity for Weight Loss? (2017) (7)
- Risk stratification and selection for statin therapy: going beyond Framingham. (2014) (7)
- Multiomics Screening Identifies Molecular Biomarkers Causally Associated With the Risk of Coronary Artery Disease (2020) (7)
- Obesity and coronary artery calcification: Can it explain the obesity-paradox? (2015) (7)
- Meta-Analysis of Gene Level Association Tests (2013) (6)
- Can response to dietary restriction predict weight loss after Roux‐en‐Y gastroplasty? (2016) (6)
- Analysis of cholesteryl ester transfer activity in adipose tissue. (1996) (6)
- Limitations of statin monotherapy for the treatment of dyslipidemia: a projection based on the Canadian lipid study – observational (2009) (6)
- A Low‐Frequency Variant in MAPK14 Provides Mechanistic Evidence of a Link With Myeloperoxidase: A Prognostic Cardiovascular Risk Marker (2014) (6)
- Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery Disease (2017) (6)
- Erratum to: Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals (2015) (5)
- Off-target effects of CRISPRa on interleukin-6 expression (2019) (5)
- Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD 3 That Confers Protection From Coronary Artery Disease (2018) (5)
- Functional Analysis of the TRIB 1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease (2014) (5)
- HeterozygousABCG5Gene Deficiency and Risk of Coronary Artery Disease (2020) (5)
- Limitations of statin monotherapy for the treatment of dyslipidemia: a projection based on the Canadian lipid study--observational. (2009) (5)
- The women's atorvastatin trial on cholesterol (WATCH): Frequency of achieving NCEP-II target LDL-C levels in women with and without established CVD (1999) (5)
- The analysis by Manuel and colleagues creates controversy with headlines, not data (2005) (5)
- Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization (2022) (5)
- Epigenome-Wide Study Identified Methylation Sites Associated with the Risk of Obesity (2021) (5)
- Abstract 15730: Serum Interferon Alpha 21 is a Biomarker of the 9p21.3 Risk Locus for Coronary Artery Disease (2011) (5)
- Miscues on the “ lack of MEF 2 A mutations ” in coronary artery disease (2005) (4)
- Function of cholesteryl ester transfer protein in reverse cholesterol transport. (1993) (4)
- Statins for primary prevention of coronary artery disease (2007) (4)
- Adverse Effects of β-Blocker Therapy on Weight Loss in Response to a Controlled Dietary Regimen. (2016) (4)
- Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity (2022) (4)
- The Cardiovascular Burden of Undiagnosed Familial Hypercholesterolemia: Need to Modify Guidelines to Encourage Earlier Diagnosis and Therapy. (2018) (4)
- Colchicine for Prevention of Atherothrombotic Events in Patients with Coronary Artery Disease: Review and Practical Approach for Clinicians. (2021) (4)
- Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult Primary Panel : (2016) (4)
- Targeting thermogenesis in the development of antiobesity drugs. (2004) (4)
- Association of muscle fiber type with measures of obesity: A systematic review (2022) (4)
- Do clustered beta-propeller domains within the N-terminus of LRP1 play a functional role? (2005) (4)
- SGCG rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program (2020) (4)
- Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region (2021) (4)
- Molecular mechanism linking a novel PCSK9 copy number variant to severe hypercholesterolemia. (2020) (3)
- Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (3)
- ‘ Clinical and Population Studies Functional Analysis of the Chromosome 9 p 21 . 3 Coronary Artery Disease Risk Locus (2009) (3)
- Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2021) (3)
- A Common Polymorphism in the FADS1 Locus Links miR1908 to Low-Density Lipoprotein Cholesterol Through BMP1 (2021) (3)
- PHACTR1: Functional Clues Linking a Genome-Wide Association Study Locus to Coronary Artery Disease. (2015) (2)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease (2019) (2)
- Treatment of hyperlipidemia in the elderly (1993) (2)
- Statin therapy in acute coronary syndrome. (2007) (2)
- Controversies in primary prevention among hyperlipidemic patients. (1999) (2)
- Hormone replacement therapy and cardiovascular disease. (2001) (2)
- Antibody phenotyping test for the human apolipoprotein E2 isoform. (2003) (2)
- P-42.: Do Decision Aids Help Post-Menopausal Women Considering Hormone Replacement Therapy? (1997) (2)
- The Editor’s Roundtable: Statin Therapy in Acute Coronary Syndrome (2007) (2)
- Peering through the darkened glass: success and disappointment in the management of cardiovascular risk. (2006) (2)
- Effects of Dietary Fatty Acids and Cholesterol on Cardiovascular Disease Risk Factors in Man (2020) (2)
- A common polymorphism that protects from cardiovascular disease increases fibronectin processing and secretion (2021) (2)
- Response to Wang et al. (2005) (2)
- Profound Elevation in LDL Cholesterol Level Following a Ketogenic Diet: A Case Series (2022) (2)
- HDL Remodeling by CETP and SR‐BI (2007) (2)
- Interindividual variability in weight loss in the treatment of obesity. (2021) (2)
- Common Polymorphism That Protects From Cardiovascular Disease Increases Fibronectin Processing and Secretion (2022) (1)
- Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (1)
- Abstract 17557: Genetic Variants Primarily Associated eith Type 2 Diabetes Also Affect Coronary Artery Disease Risk (2012) (1)
- Mitochondrial Bioenergetic Aspects of Obesity and Weight Loss (2014) (1)
- Identification of variant apolipoprotein E by isoelectric focusing and restriction isotyping in a patient with type III hyperlipoproteinemia. (1991) (1)
- Targeting skeletal muscle mitochondrial health in obesity (2022) (1)
- In people with no prior history of cardiovascular disease, high density and non-high-density lipoprotein cholesterol levels are better predictors of cardiovascular disease mortality than low-density lipoprotein levels (2002) (1)
- Coronary Artery Disease Gene Dosage of the Common Variant 9 p 21 Predicts Severity of Coronary Artery Disease (1)
- CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression (2020) (1)
- miR1908-5p regulates energy homeostasis in hepatocyte models (2021) (1)
- A PHARMACOGENOMIC APPROACH TO ANTIPLATELET THERAPY IN STEMI PATIENTS: REASSESSMENT OF ANTI-PLATELET THERAPY USING AN INDIVIDUALIZED STRATEGY IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION (THE RAPID STEMI STUDY) (2013) (1)
- Abstract 1436: Gene Dosage of the Common Variant 9p21 Predicts Severity of Coronary Atheromatous Burden (2008) (1)
- FUNCTIONAL RELATIONSHIP OF THE SMAD3 LOCUS TO CORONARY ARTERY DISEASE (CAD) (2015) (1)
- P1 Niacin Inhibits Chain ATP Synthase Cell Surface Expression in HepG2 Cells: Mechanistic Implications for Raising HDL (2010) (1)
- Understanding the Function of a Locus Using the Knowledge Available at Single-Nucleotide Polymorphisms (2021) (1)
- Design, Rationale, and Preliminary Results of the Canadian Homozygous Familial Hypercholesterolemia Registry: 2008 to 2022 Update (2023) (1)
- 4.P.91 Plasma CETP concentration and activity in insulin dependent diabetes mellitus as compared to normal controls (1997) (1)
- The primacy of diet in the treatment of hyperlipidemia. (1989) (1)
- Correction: Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells (2012) (1)
- Plasma lipoprotein phenotype in response to cholesteryl ester transfer protein levels in dyslipoproteinemia. (1991) (1)
- Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease (2022) (1)
- The Sum of Its Parts: The Polygenic Basis of Coronary Artery Disease. (2016) (1)
- 421 Functional Relationship of the COL4A1/COL4A2 Locus on Chromosome 13q34 to Coronary Artery Disease (CAD) (2012) (1)
- Abstract 17892: Network-Driven Integrative Genomics Analysis of the Cardiogram Gwas Reveals Key Drivers and Subnetworks of Coronary Artery Disease (2011) (1)
- Transcript expression-aware annotation improves rare variant interpretation (2020) (1)
- Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (2021) (1)
- Errata (2011) (0)
- TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha (2017) (0)
- Author's response to reviews Title: Gene expression profiling in whole blood identifies distinct biological pathways associated with obesity Authors: (2010) (0)
- Abstract MP57: Pathway and Network Analysis of GWAS reveals Novel Candidate Causal Links between Key Biological Processes and Coronary Artery Disease (2014) (0)
- Abstract: 500 THE GENETICS OF ATHEROSCLEROSIS (2009) (0)
- Abstract 17862: Protection From Acute Myocardial Infarction in Humans is Associated With a Genetic Variation Near a Novel Gene Encoding a Human Protein Binding to a Mouse Model of Vulnerable Plaque (2010) (0)
- A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease. (2022) (0)
- Skeletal Muscle Exercise T-112-P The Role of Prenyl Diphosphate Synthase Subunit 1 in Cellular Bioenergetics and Its Implications in Obesity (2013) (0)
- Author Correction: Evaluating drug targets through human loss-of-function genetic variation (2021) (0)
- 338 Interferon alpha 21 levels are elevated in peripheral blood lymphocytes and aortic smooth muscle cells with the 9p21.3 coronary artery disease risk genotype (2011) (0)
- Abstract 3451: Risk for Coronary Artery Disease at the 9p21.3 Locus Is Abolished by a Protective Locus at 8p21.3 Identified by a Genome-Wide Association Study (2008) (0)
- 2.P.1 Selective uptake of HDL-CE by human adipose tissue is an LRP-dependent process (1997) (0)
- Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2020) (0)
- A structural variation reference for medical and population genetics (2020) (0)
- Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice (2020) (0)
- Age-related lower HDL plasma level is not attributed to modification of CETP concentration (1999) (0)
- Distribution of ancestry in each cohort. (2020) (0)
- Chapter hormone replacement therapy and cardiovascular disease (2001) (0)
- Author Correction: Transcript expression-aware annotation improves rare variant interpretation (2021) (0)
- IRF 2 BP 2 Inhibits Macrophage Inflammation 673 Plasmid Constructs , Lentiviral Vector , Transfections , and Luciferase Assays (2015) (0)
- Atherosclerosis in SR-BI Deficient Mice Cholesteryl Ester Transfer Protein ( CETP ) Expression Protects Against Diet Induced (2007) (0)
- Abstract 403: A Common Polymorphism Connects Propionyl-coa Carboxylase To Coronary Artery Disease (2022) (0)
- Abstract 2070: Identification of SPG7 as a Novel Risk Locus for Coronary Artery Disease by Genome-wide Association (2009) (0)
- Abstract: S5-6 GENETICS OF CORONARY HEART DISEASE (2009) (0)
- 4.14: Computed tomographic coronary angiography and Framingham risk factor scores: Further support for direct screening for atherosclerosis (2008) (0)
- Correction: Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells (2012) (0)
- Identification of Cathepsin D, a Lysosomal Protease Involved in ApoA-I Mediated-Lipid Efflux; a New Insight from Microarray Analysis (2006) (0)
- Abstract 19809: Interferon Regulatory Factor 2 Binding Protein 2 Inhibits Macrophage Inflammation and Reduces Susceptibility to Atherosclerosis in Mice and Humans (2015) (0)
- Antibody Phenotyping Test for the Human Apolipopro- (2003) (0)
- Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Medical Sequencing at the extremes of Human Body Mass Permalink (0)
- Disappearance of acanthosis nigricans following discontinuation of niacin despite minimal change in insulin sensitivity (1996) (0)
- Chapter 2. Monogenic Hypercholesterolemia (2008) (0)
- Genome-wide screening identifies DNA methylation sites that regulate the blood proteome. (2022) (0)
- Assessing Cardiovascular Risk to Optimally Stratify Low- and Moderate- Risk Patients (2009) (0)
- Objective—We sought to examine the risk of mortality associated with nonobstructive coronary artery disease (CAD) and to determine the impact of baseline statin and aspirin use on mortality. Approach and Results—Coronary computed tomographic angiography permits direct visualization of nonobstructive (2015) (0)
- 2.P.7 Age-related decline in plasma CETP and CETP mRNA expression in human adipose tissue (1997) (0)
- Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region (2021) (0)
- Whole-gene Duplication of PCSK9 as a Novel Genetic Mechanism for Familial Hypercholesterolemia (2018) (0)
- Ucp3 expression and function:Studies in transgenic mice and human muscle (2001) (0)
- Abstract 610: Netrin-1 Promotes Macrophage Accumulation and Insulin Resistance in Obesity (2014) (0)
- Growth hormone replacement theraphy to GH deficient adults lowers plasma CETP concentration (1999) (0)
- Regulation of TRIB1 abundance in hepatoma models (2022) (0)
- About the authors (2007) (0)
- Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (0)
- Phenotypic Expression of Hepatic Lipase Deficiency (1989) (0)
- Association of MARC1 A165T with metabolic traits. (2020) (0)
- Abstract 18993: Genetic Variants Primarily Associated With Inflammatory Bowel Disease Do Not Associate With Coronary Artery Disease (2014) (0)
- PSeudoautosomal region 1 and predisposition to coronary artery disease. (2017) (0)
- Improved Diagnostic Accuracy When Combining Computed Tomography Angiography and Corrected Coronary Opacification in Patients with Coronary Stents (2013) (0)
- The effect of LRRK2 loss-of-function variants in humans (2020) (0)
- CETP concentration is not modified but PLTP activity is increased and correlates negatively with plasma HDL-C levels in the elderly (2000) (0)
- 298 Influence Of Genetic Polymorphisms In Combination With Clinical Variables On High On-Clopidogrel Platelet Reactivity In Patients Undergoing Percutaneous Coronary Intervention (2012) (0)
- Author Correction: A structural variation reference for medical and population genetics (2021) (0)
- COMMON OR RARE GENETIC VARIATION IN THE CHEMOKINE RECEPTORS CCR2, CCR5, AND CX3CR1 DOES NOT RELATE TO CORONARY HEART DISEASE OR MYOCARDIAL INFARCTION IN HUMANS (2016) (0)
- Evidence for a shared genetic determination of Ischemic Stroke And Coronary Artery Disease - a genome-wide analysis (2013) (0)
- Abstract 17262: Identification of a Rare Variant Near Neurexin 1 Associated with Coronary Artery Disease (2010) (0)
- Abstract 361: Epistasis Analysis Identifies Extracellular Matrix Genes Interacting With the COL4A1/COL4A2 Coronary Artery Disease Locus (2014) (0)
- Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Lack of Support for the Association Between GAD 2 Polymorphisms and Severe Human Obesity Permalink (2005) (0)
- Supplementary Material (nature09270-s1) (2012) (0)
- Abstract 18325: Functional Relationship of the COL4A1/COL4A2 Locus on Chromosome 13q34 to Coronary Artery Disease (CAD) (2013) (0)
- 1 Subsequent Event Risk in Individuals with Established Coronary Heart Disease : Design and Rationale of the GENIUS-CHD Consortium Running title : (2019) (0)
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (0)
- Genetics of Atherosclerosis (2009) (0)
- Training/Practice Contemporary Issues in Cardiology Practice Risk Stratification and Selection for Statin Therapy: Going (2014) (0)
- 2.P.8 Expression of CETP mRNA by stromal vascular cells of human adipose tissue (1997) (0)
- Obesity shows preserved plasma proteome in large independent clinical cohorts (2018) (0)
- PO23-785 LDL-C AND CRP IN ATORVASTATIN TREATED STABLE CORONARY ARTERY DISEASE PATIENTS: THE CAP (COMPARATIVE ATORVASTATIN PLEOTROPIC) EFFECTS STUDY RESULTS (2007) (0)
- Abstract 610: Functional Relationship of The CARS2 Locus to Coronary Artery Disease (2018) (0)
- Abstract 433: Examination of Factors Affecting the Association of PCSK9 With Low-Density Lipoprotein Particles in Human Plasma (2014) (0)
- Beyond calories: Genetic determinants of eating, satiety and metabolism underlying obesity (2008) (0)
- Clinical Research Adverse Effects of b-Blocker Therapy on Weight Loss in Response to a Controlled Dietary Regimen (2016) (0)
- Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (2020) (0)
- Abstract 1095: Vascular Calcifications in Homozygote Familial Hypercholesterolemia: the Canadian Experience (2007) (0)
- Abstract 815: Comparative Atorvastatin Pleiotropic effects (CAP) study (2006) (0)
- Abstract 14363: Genetics of Coronary Atherosclerotic Plaque Rupture and Myocardial Infarction (2010) (0)
- Epigenetic programming and resistance to weight loss (2011) (0)
- Investigating The Metabolic Basis for Weight loss Variability in Obese Humans (2013) (0)
- The mutational constraint spectrum quantified from variation in 141,456 humans (2020) (0)
- Association analyses based on false discovery rate implicate 243 susceptibility loci for coronary artery disease (2017) (0)
- Evaluating drug targets through human loss-of-function genetic variation (2020) (0)
- Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2021) (0)
- Abstract 364: Ottawa Heart Genomic Study: Discovery Of Novel Genes For Coronary Artery Disease By Genome-wide Association Utilizing The 500k SNP Array (2007) (0)
- MPS 01-02 GENOME WIDE HOMOZYGOSITY ANALYSIS - ASSOCIATION WITH CORONARY ARTERY DISEASE AND GENE EXPRESSION IN MONOCYTES AND MACROPHAGES (2016) (0)
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