Ryoichi Takayanagi
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Biology
Ryoichi Takayanagi's Degrees
- PhD Genetics University of Tokyo
- Masters Bioinformatics Kyoto University
- Bachelors Biology Kyoto University
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(Suggest an Edit or Addition)Ryoichi Takayanagi's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
- Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice (2009) (925)
- Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians (2011) (581)
- Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians (2011) (534)
- Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. (2007) (456)
- Establishment and Characterization of a Steroidogenic Human Granulosa-Like Tumor Cell Line, KGN, That Expresses Functional Follicle-Stimulating Hormone Receptor. (2001) (392)
- Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma. (2015) (383)
- SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease. (2008) (313)
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation (2015) (285)
- Epidemiological trends of pancreatic and gastrointestinal neuroendocrine tumors in Japan: a nationwide survey analysis (2014) (271)
- Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts. (2005) (250)
- Confirmation of Multiple Risk Loci and Genetic Impacts by a Genome-Wide Association Study of Type 2 Diabetes in the Japanese Population (2009) (250)
- Atrazine-Induced Aromatase Expression Is SF-1 Dependent: Implications for Endocrine Disruption in Wildlife and Reproductive Cancers in Humans (2007) (248)
- Structure of rat atrial natriuretic factor precursor deduced from cDNA sequence (1984) (241)
- Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma. (2014) (229)
- Liver X receptor in cooperation with SREBP‐1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease (2008) (215)
- Presence of non‐selective type of endothelin receptor on vascular endothelium and its linkage to vasodilation (1991) (208)
- Enhanced secretion of endothelin‐1 by elevated glucose levels from cultured bovine aortic endothelial cells (1990) (205)
- Blood Pressure and Hypertension Are Associated With 7 Loci in the Japanese Population (2010) (204)
- Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis. (2004) (197)
- Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians (2011) (191)
- Aromatase in bone cell: Association with osteoporosis in postmenopausal women (1995) (188)
- GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases. (2012) (182)
- Androgen-insensitivity syndrome as a possible coactivator disease. (2000) (181)
- Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. (2013) (181)
- NADH- and NADPH-dependent lipid peroxidation in bovine heart submitochondrial particles. Dependence on the rate of electron flow in the respiratory chain and an antioxidant role of ubiquinol. (1980) (178)
- Two distinct forms of receptors for atrial natriuretic factor in bovine adrenocortical cells. Purification, ligand binding, and peptide mapping. (1987) (173)
- Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. (2014) (163)
- Insulin-like Growth Factor 1/Insulin Signaling Activates Androgen Signaling through Direct Interactions of Foxo1 with Androgen Receptor* (2007) (162)
- Guidelines on the management and treatment of glucocorticoid-induced osteoporosis of the Japanese Society for Bone and Mineral Research: 2014 update (2014) (152)
- Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN. (2001) (151)
- Relationship between Gilbert syndrome and prevalence of vascular complications in patients with diabetes. (2007) (150)
- Clinical impact of endoscopic submucosal dissection for superficial adenocarcinoma located at the esophagogastric junction. (2008) (148)
- Genome-wide association study of coronary artery disease in the Japanese (2011) (147)
- Changes in the content of atrial natriuretic factor with the progression of hypertension in spontaneously hypertensive rats. (1985) (144)
- Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase. (2010) (143)
- Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells. (2000) (142)
- Treatment for autoimmune pancreatitis: consensus on the treatment for patients with autoimmune pancreatitis in Japan (2007) (135)
- Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism. (2011) (130)
- The Subnuclear Three-dimensional Image Analysis of Androgen Receptor Fused to Green Fluorescence Protein* (2001) (129)
- Guidelines on the management and treatment of glucocorticoid-induced osteoporosis of the Japanese Society for Bone and Mineral Research (2004) (2004) (127)
- Dietary patterns and C-reactive protein in Japanese men and women. (2008) (121)
- Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor. (1992) (119)
- Purification and characterization of a phosphoramidon-sensitive endothelin-converting enzyme in porcine aortic endothelium. OFF. (1993) (117)
- Serum dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) in Alzheimer's disease and in cerebrovascular dementia. (1996) (112)
- Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells. (2014) (111)
- Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice (2015) (110)
- Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance (2011) (108)
- Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance (2014) (106)
- Purification and characterization of two types of atrial natriuretic factor receptors from bovine adrenal cortex: guanylate cyclase-linked and cyclase-free receptors. (1987) (102)
- Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation (2010) (101)
- Brachial-Ankle Pulse Wave Velocity Predicts All-Cause Mortality and Cardiovascular Events in Patients With Diabetes: The Kyushu Prevention Study of Atherosclerosis (2014) (100)
- Cloning and sequence analysis of a cDNA encoding human non-selective type of endothelin receptor. (1991) (98)
- The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets. (2008) (98)
- Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice. (2007) (94)
- Androgens and metabolic syndrome: Lessons from androgen receptor knock out (ARKO) mice (2008) (93)
- Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration (2015) (93)
- Maternal high-fat diet induces insulin resistance and deterioration of pancreatic β-cell function in adult offspring with sex differences in mice. (2014) (93)
- Effects of changes in water-sodium balance on levels of atrial natriuretic factor messenger RNA and peptide in rats. (1985) (89)
- 1,25-Dihydroxyvitamin D3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts. (1996) (88)
- Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes. (1995) (87)
- Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor. (2001) (86)
- Combined treatment with specific ligands for PPARγ:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells (2001) (83)
- Superoxide-forming NADPH oxidase preparation of pig polymorphonuclear leucocyte. (1982) (81)
- Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease. (2011) (80)
- Inverse associations of serum bilirubin with high sensitivity C-reactive protein, glycated hemoglobin, and prevalence of type 2 diabetes in middle-aged and elderly Japanese men and women. (2010) (80)
- Structural characterization of human Ad4bp (SF-1) gene. (1996) (74)
- GLP-1 analog liraglutide protects against cardiac steatosis, oxidative stress and apoptosis in streptozotocin-induced diabetic rats. (2015) (74)
- Molecular characteristics of colorectal neuroendocrine carcinoma; similarities with adenocarcinoma rather than neuroendocrine tumor. (2015) (73)
- Adipose tissue-derived and bone marrow-derived mesenchymal cells develop into different lineage of steroidogenic cells by forced expression of steroidogenic factor 1. (2008) (69)
- Evaluation of Pancreatic Endocrine and Exocrine Function in Patients With Autoimmune Pancreatitis (2007) (69)
- The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway. (2013) (67)
- Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II. (2007) (67)
- Effects of 16-Week Consumption of Caffeinated and Decaffeinated Instant Coffee on Glucose Metabolism in a Randomized Controlled Trial (2012) (67)
- Hepatoid adenocarcinoma of the stomach: histogenesis and progression in association with intestinal phenotype. (2007) (66)
- The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years (2010) (66)
- Synthesis and presence of atrial natriuretic factor in rat ventricle. (1987) (65)
- The presence of both the amino- and carboxyl-terminal domains in the AR is essential for the completion of a transcriptionally active form with coactivators and intranuclear compartmentalization common to the steroid hormone receptors: a three-dimensional imaging study. (2002) (64)
- Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells. (2008) (63)
- Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6. (2008) (63)
- Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus (2010) (62)
- An increase in the serum amylase level in patients after peroral double-balloon enteroscopy: an association with the development of pancreatitis. (2006) (62)
- Potential role of branched‐chain amino acids in glucose metabolism through the accelerated induction of the glucose‐sensing apparatus in the liver (2011) (62)
- Aromatase in bone: roles of Vitamin D3 and androgens (2003) (60)
- Thiazolidinedione Induces Apoptosis and Monocytic Differentiation in the Promyelocytic Leukemia Cell Line HL60 (1999) (59)
- Multiple subtypes of endothelin receptors in porcine tissues: characterization by ligand binding, affinity labeling and regional distribution (1991) (59)
- CD4+CD25+ Regulatory T Cells Suppress Th17-Responses in an Experimental Colitis Model (2011) (59)
- Protein kinase A potentiates adrenal 4 binding protein/steroidogenic factor 1 transactivation by reintegrating the subcellular dynamic interactions of the nuclear receptor with its cofactors, general control nonderepressed-5/transformation/transcription domain-associated protein, and suppressor, dos (2004) (58)
- Profile of Participants and Genotype Distributions of 108 Polymorphisms in a Cross-Sectional Study of Associations of Genotypes With Lifestyle and Clinical Factors: A Project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study (2011) (58)
- Association of borderline ankle-brachial index with mortality and the incidence of peripheral artery disease in diabetic patients. (2014) (57)
- Neuroticism and extraversion personality traits, health behaviours, and subjective well-being: the Fukuoka Study (Japan) (2012) (55)
- Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians (2014) (55)
- Biliverdin protects against the deterioration of glucose tolerance in db/db mice (2011) (55)
- Immunohistochemical study of cytochrome b5 in human adrenal gland and in adrenocortical adenomas from patients with Cushing's syndrome. (1998) (55)
- The relationship of coffee and green tea consumption with high-sensitivity C-reactive protein in Japanese men and women (2010) (54)
- Differential expression of PPAR γ1 and γ2 isoforms in human adipose tissue (1997) (53)
- Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance (2013) (53)
- Dietary Patterns and A1C in Japanese Men and Women (2008) (53)
- New mutations of DAX-1 genes in two Japanese patients with X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. (1996) (51)
- Differential diagnosis of cystic tumors of the pancreas by endoscopic ultrasonography. (2009) (51)
- Retroperitoneal fibrosis associated with immunoglobulin G4-related disease. (2013) (50)
- Lactate dehydrogenase production in hepatocytes is increased at an early stage of acute liver failure. (2011) (49)
- Steroidogenic factor 1/adrenal 4 binding protein transforms human bone marrow mesenchymal cells into steroidogenic cells. (2007) (49)
- Relative inactivation of steroidogenic enzyme activities of in vitro vitamin E-depleted human adrenal microsomes by lipid peroxidation. (1986) (49)
- Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats (2008) (49)
- Nur77, a member of the steroid receptor superfamily, antagonizes negative feedback of ACTH synthesis and secretion by glucocorticoid in pituitary corticotrope cells. (1998) (48)
- Activation Function-1 Domain of Androgen Receptor Contributes to the Interaction between Subnuclear Splicing Factor Compartment and Nuclear Receptor Compartment (2002) (48)
- Dehydroepiandrosterone (DHEA) as a possible source for estrogen formation in bone cells: correlation between bone mineral density and serum DHEA-sulfate concentration in postmenopausal women, and the presence of aromatase to be enhanced by 1,25-dihydroxyvitamin D3 in human osteoblasts (2002) (47)
- Aromatase activity in human osteoblast-like osteosarcoma cell (1993) (45)
- A single amino acid substitution (Met786----Val) in the steroid-binding domain of human androgen receptor leads to complete androgen insensitivity syndrome. (1992) (45)
- Impairment of vesicular ATP release affects glucose metabolism and increases insulin sensitivity (2014) (45)
- Atrial and brain natriuretic peptide in adrenal steroidogenesis (1991) (45)
- cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line. (1995) (44)
- Regulation of aromatase by nuclear receptors (2001) (43)
- Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size (2012) (43)
- High expression of cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome associated with high secretion of adrenal androgens. (1993) (43)
- A new parameter using serum lactate dehydrogenase and alanine aminotransferase level is useful for predicting the prognosis of patients at an early stage of acute liver injury: A retrospective study (2008) (43)
- Human pituitary tumor transforming gene (hPTTG) inhibits human lung cancer A549 cell growth through activation of p21(WAF1/CIP1 ). (2003) (43)
- GLI1, a crucial mediator of sonic hedgehog signaling in prostate cancer, functions as a negative modulator for androgen receptor. (2011) (42)
- Regional increase of cyclic GMP by atrial natriuretic factor in rat brain: markedly elevated response in spontaneously hypertensive rats. (1986) (42)
- No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia. (1994) (41)
- Catechol estrogens are more potent antioxidants than estrogens for the Cu(2+)-catalyzed oxidation of low or high density lipoprotein: antioxidative effects of steroids on lipoproteins. (1994) (41)
- Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion. (2015) (40)
- Sertoli cell function declines earlier than Leydig cell function in aging Japanese men. (1994) (40)
- Generation and characterization of T1R2-LacZ knock-in mouse. (2010) (38)
- LOW‐FREQUENCY OF BACTEREMIA AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION OF THE STOMACH (2011) (38)
- Inhibition of chymase protects against diabetes-induced oxidative stress and renal dysfunction in hamsters. (2010) (37)
- CTLA-4Ig immunotherapy of obesity-induced insulin resistance by manipulation of macrophage polarization in adipose tissues. (2013) (37)
- The Current Strategy for Managing Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1 (2012) (37)
- Prognosis of primary aldosteronism in Japan: results from a nationwide epidemiological study. (2014) (36)
- Nuclear Compartmentalization of N-CoR and Its Interactions with Steroid Receptors (2006) (35)
- Identification of a peptidase which processes atrial natriuretic factor precursor to its active form with 28 amino acid residues in particulate fractions of rat atrial homogenate. (1987) (35)
- High prevalence of peripheral arterial disease diagnosed by low ankle-brachial index in Japanese patients with diabetes: the Kyushu Prevention Study for Atherosclerosis. (2008) (35)
- Type 1 angiotensin II receptors of adrenal tumors (1995) (34)
- A novel DPP-4 inhibitor teneligliptin scavenges hydroxyl radicals: In vitro study evaluated by electron spin resonance spectroscopy and in vivo study using DPP-4 deficient rats. (2016) (34)
- Predictive Factors for Colonic Diverticular Rebleeding: A Retrospective Analysis of the Clinical and Colonoscopic Features of 111 Patients (2012) (34)
- Suitability of the expanded indication criteria for the treatment of early gastric cancer by endoscopic submucosal dissection: Japanese multicenter large-scale retrospective analysis of short- and long-term outcomes (2015) (34)
- Proposed diagnostic criteria for subclinical Cushing's syndrome associated with adrenal incidentaloma. (2013) (34)
- The Expression of Both Peroxisome Proliferator-Activated Receptor Delta and Cyclooxygenase-2 in Tissues Is Associated with Poor Prognosis in Colorectal Cancer Patients (2011) (34)
- In vivo and in vitro evidence for the production of inhibin-like immunoreactivity in human adrenocortical adenomas and normal adrenal glands: relatively high secretion from adenomas manifesting Cushing's syndrome. (1995) (34)
- Mechanism of abnormal production of adrenal androgens in patients with adrenocortical adenomas and carcinomas. (1994) (33)
- Epidemiologic study of adrenal gland disorders in Japan. (2000) (33)
- Randomized comparison of pitavastatin and pravastatin treatment on the reduction of urinary albumin in patients with type 2 diabetic nephropathy (2012) (33)
- Short- and long-term outcomes of endoscopic resection of rectal neuroendocrine tumours: analyses according to the WHO 2010 classification (2016) (32)
- Molecular cloning and characterization of the promoter for human type-1 angiotensin II receptor gene. (1994) (32)
- Renoprotective effect of a novel selective PPARα modulator K-877 in db/db mice: A role of diacylglycerol-protein kinase C-NAD(P)H oxidase pathway. (2017) (32)
- Lipid peroxidation and the reduction of ADP-Fe3+ chelate by NADH-ubiquinone reductase preparation from bovine heart mitochondria. (1980) (32)
- Low level of glucocorticoid receptor messenger ribonucleic acid in pituitary adenomas manifesting Cushing's disease with resistance to a high dose‐dexamethasone suppression test (1998) (31)
- Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of peripancreatic tuberculous lymphadenitis (2007) (31)
- Dehydroepiandrosterone markedly inhibits the accumulation of cholesteryl ester in mouse macrophage J774-1 cells. (1996) (31)
- Serum chromogranin A is a useful marker for Japanese patients with pancreatic neuroendocrine tumors (2014) (31)
- Multigene Analysis Unveils Distinctive Expression Profiles of Helper T-cell–related Genes in the Intestinal Mucosa that Discriminate Between Ulcerative Colitis and Crohn's Disease (2014) (31)
- Real-world effectiveness of daily teriparatide in Japanese patients with osteoporosis at high risk for fracture: final results from the 24-month Japan Fracture Observational Study (JFOS) (2017) (30)
- Chromogranin B (secretogranin I), a neuroendocrine‐regulated secretory protein, is sorted to exocrine secretory granules in transgenic mice (1998) (30)
- A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells (2000) (30)
- Calpain-Dependent Degradation of Nucleoporins Contributes to Motor Neuron Death in a Mouse Model of Chronic Excitotoxicity (2017) (30)
- Resveratrol, a phytoestrogen found in red wine, down-regulates protein S expression in HepG2 cells. (2011) (30)
- Single amino acid substitution (840Arg-->His) in the hormone-binding domain of the androgen receptor leads to incomplete androgen insensitivity syndrome associated with a thermolabile androgen receptor. (1994) (30)
- Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis (2011) (30)
- SMAD2 disruption in mouse pancreatic beta cells leads to islet hyperplasia and impaired insulin secretion due to the attenuation of ATP-sensitive K+ channel activity (2013) (29)
- SREBP-1 c , regulated by the insulin and AMPK signaling pathways , plays a role in nonalcoholic fatty liver disease (29)
- Helix 8 of leukotriene B4 receptor 1 inhibits ligand‐induced internalization (2012) (29)
- Atrioactivase, a specific peptidase in bovine atria for the processing of pro-atrial natriuretic factor. Purification and characterization. (1988) (29)
- Regional distribution of endothelin receptor in porcine cardiovascular tissues (1990) (29)
- In‐vitro evidence for the regulation of 17,20‐lyase activity by cytochrome b5 in adrenocortical adenomas from patients with Cushing's syndrome (1994) (28)
- Fractalkine and TGF-beta1 levels reflect the severity of chronic pancreatitis in humans. (2008) (28)
- Eldecalcitol for the treatment of osteoporosis (2013) (28)
- Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model (2012) (28)
- Impaired nuclear translocation, nuclear matrix targeting, and intranuclear mobility of mutant androgen receptors carrying amino acid substitutions in the deoxyribonucleic acid-binding domain derived from androgen insensitivity syndrome patients. (2005) (27)
- Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets (2007) (27)
- Reduced Expression of Adipose Triglyceride Lipase Enhances Tumor Necrosis Factor α-induced Intercellular Adhesion Molecule-1 Expression in Human Aortic Endothelial Cells via Protein Kinase C-dependent Activation of Nuclear Factor-κB* (2011) (27)
- Exenatide improves hepatic steatosis by enhancing lipid use in adipose tissue in nondiabetic rats. (2014) (27)
- Mucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors. (2013) (27)
- Thiazolidinedione suppresses the expression of erythroid phenotype in erythroleukemia cell line K562. (2000) (27)
- Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis. (2008) (26)
- Functional potentiation of leptin-signal transducer and activator of transcription 3 signaling by the androgen receptor. (2008) (26)
- Vitamin K2 modulates differentiation and apoptosis of both myeloid and erythroid lineages (2010) (25)
- Epidemiological Study of Pancreatic Diabetes in Japan in 2005: A Nationwide Study (2010) (25)
- Effect of atrial natriuretic factor on central angiotensin II-induced responses in rats (1986) (25)
- Lipid peroxidation by bovine heart submitochondrial particles stimulated by 1,1'-dimethyl-4,4'-bipyridylium dichloride (paraquat). (1983) (25)
- Expression of an orphan nuclear receptor DAX‐1 in human pituitary adenomas (1998) (24)
- Reduction of fatty acid oxidation and responses to hypoxia correlate with the progression of de-differentiation in HCC. (2013) (24)
- Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes (2012) (24)
- A rare case of 46,XX true hermaphroditism with hidden mosaicism with sex-determining region Y chromosome-bearing cells in the gonads. (1998) (23)
- Genetic impact on uric acid concentration and hyperuricemia in the Japanese population. (2013) (23)
- Mechanism of dissociation of cortisol and adrenal androgen secretion after removal of adrenocortical adenoma in patients with Cushing's syndrome. (1985) (23)
- Tob proteins suppress steroid hormone receptor-mediated transcriptional activation (2005) (23)
- Aberrant activation-induced cytidine deaminase expression is associated with mucosal intestinalization in the early stage of gastric cancer (2011) (23)
- Efficacy and safety of bazedoxifene for postmenopausal osteoporosis (2011) (23)
- Vasoactive Intestinal Peptide (VIP) and VIP Receptors-Elucidation of Structure and Function for Therapeutic Applications (2011) (23)
- Interferon-gamma suppresses thyrotropin receptor promoter activity by reducing thyroid transcription factor-1 (TTF-1) binding to its recognition site. (1996) (23)
- Pneumocystis Pneumonia During Combined Therapy of Infliximab, Corticosteroid, and Azathioprine in a Patient with Crohn’s Disease (2007) (22)
- Mutual transactivational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization (2007) (22)
- Multiple ulcers in the small and large intestines occurred during tocilizumab therapy for rheumatoid arthritis. (2011) (22)
- Transcriptional regulation of the human FTZ-F1 gene encoding Ad4BP/SF-1. (2000) (22)
- The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats. (1995) (21)
- Coregulator-related diseases. (2004) (21)
- Changes in serum sex hormone profiles after short-term low-dose administration of dehydroepiandrosterone (DHEA) to young and elderly persons. (2007) (21)
- PSCs and GLP-1R: occurrence in normal pancreas, acute/chronic pancreatitis and effect of their activation by a GLP-1R agonist (2014) (21)
- The Simultaneous Expression of Peroxisome Proliferator-Activated Receptor Delta and Cyclooxygenase-2 May Enhance Angiogenesis and Tumor Venous Invasion in Tissues of Colorectal Cancers (2009) (21)
- Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice. (2013) (21)
- Vasoactive intestinal peptide reduces oxidative stress in pancreatic acinar cells through the inhibition of NADPH oxidase (2011) (21)
- Cyclic Cushing's disease in long-term remission with a daily low dose of bromocriptine. (1996) (20)
- Atrial natriuretic factor in spontaneously hypertensive rats: concentration changes with the progression of hypertension and elevated formation of cyclic GMP. (1986) (20)
- EFFECT OF PORCINE BRAIN NATRIURETIC PEPTIDE (pBNP) ON HUMAN ADRENOCORTICAL STEROIDOGENESIS (1989) (20)
- A sustained prostacyclin analog, ONO-1301, attenuates pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats. (2014) (20)
- Alendronate improves QOL of postmenopausal women with osteoporosis (2010) (20)
- Testicular zinc finger protein recruits histone deacetylase 2 and suppresses the transactivation function and intranuclear foci formation of agonist-bound androgen receptor competitively with TIF2 (2006) (20)
- Smad2 Protein Disruption in the Central Nervous System Leads to Aberrant Cerebellar Development and Early Postnatal Ataxia in Mice* (2011) (19)
- Combination of hepatocellular markers is useful for prognostication in gastric hepatoid adenocarcinoma. (2014) (19)
- Androgen insensitivity syndrome due to new mutations in the DNA-binding domain of the androgen receptor (1996) (19)
- Clinical characteristics associated with esophageal motility function (2016) (19)
- ERK pathway and sheddases play an essential role in ethanol-induced CX3CL1 release in pancreatic stellate cells (2013) (19)
- Dehydroepiandrosterone negatively regulates the p38 mitogen-activated protein kinase pathway by a novel mitogen-activated protein kinase phosphatase. (2005) (18)
- Association of single nucleotide polymorphisms in secreted frizzled‐related protein 1 gene with bone mineral density in Japanese women (2009) (18)
- A high prevalence of extreme hyperferritinemia in acute hepatitis patients (2009) (18)
- Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. (2016) (18)
- Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy (2016) (17)
- Dietary vitamin D3 improves postprandial hyperglycemia in aged mice. (2015) (17)
- p66Shc Signaling Mediates Diabetes-Related Cognitive Decline (2018) (17)
- Key endoscopic ultrasound features of pancreatic ductal adenocarcinoma smaller than 20 mm (2014) (17)
- Activin stimulates CYP19A gene expression in human ovarian granulosa cell-like KGN cells via the Smad2 signaling pathway. (2013) (17)
- Endoscopic approach through the minor papilla for the management of pancreatic diseases. (2013) (17)
- A zinc finger protein TZF is a novel corepressor of androgen receptor. (2005) (17)
- A case of lipomatous pseudohypertrophy of the pancreas diagnosed by typical imaging. (2010) (16)
- CD30 Ligand/CD30 Interaction Is Involved in Pathogenesis of Inflammatory Bowel Disease (2012) (16)
- Mortalin is a novel mediator of erythropoietin signaling (2007) (16)
- Human recombinant activin-A modulates the steroidogenesis of cultured bovine adrenocortical cells. (1992) (16)
- Behavioral and clinical correlates of serum bilirubin concentrations in Japanese men and women (2013) (16)
- Persistent gut motor dysfunction in a murine model of T‐cell‐induced enteropathy (2010) (16)
- [Rho-kinase inhibitor]. (2004) (15)
- Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d‐galactosamine (2007) (15)
- A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator and possesses metabolic effects with little impact on the prostate. (2009) (15)
- Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4‐associated oxidative stress in diabetic hamsters (2012) (15)
- Opposite effects of alternative TZF spliced variants on androgen receptor. (2006) (15)
- Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis (2013) (15)
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- [Development of BMP-related drugs]. (2005) (0)
- Molecular Biology of Endothelin-Converting Enzyme (ECE) (1998) (0)
- Impact of double-balloon endoscopy on the diagnosis lar lymphomas : a case series (2009) (0)
- Erratum: Partial purification of phosphoramidon-sensitive endothelin converting enzyme in porcine aortic endothelial cells: High affinity for Ricinus communis agglutinin (Biochemical and Biophysical Research Communications (June 15, 1992) 185:2 (611-616)) (1992) (0)
- Asynchronous Rhythm of Steroidogenic Factor 1 and Period Homolog 2 mRNA Expression in Mouse Y1 Adrenocorticol Tumor Cells (2010) (0)
- [Glucocorticoid-induced osteoporosis]. (2006) (0)
- Tu1194 Clinical Characteristics Associated With Function of Esophageal Motility: A Retrospective Analysis of 97 Patients (2015) (0)
- Tu1829 Trypsin Induced BiPhasic Contraction and Relaxation in the Porcine Lower Esophageal Sphincter (2013) (0)
- [Comprehensive geriatrics--primary prevention]. (2004) (0)
- Tu1977 IL-17 Induces Hypercontractility in Intestinal Smooth Muscle Strips and Cells via Nf?B Signaling (2012) (0)
- [Phe21]big endothelin‐1(18–34) and [Ala31]big endothelin‐1(18–34) inhibit the human endothelin‐converting enzyme‐1 (ECE‐1) expressed in CHO‐K1 cells in a different fashion (1997) (0)
- [Case of Zollinger-Ellison syndrome diagnosed three years after ulcer perforation in the third portion of the duodenum]. (2008) (0)
- p66Shc Signaling Mediates Diabetes-Related Cognitive Decline (2018) (0)
- Mo1415 Usefulness of Endoscopic Ultrasonograpy in the Diagnosis of Pancreatic Neuroendocrine Tumors (2011) (0)
- [Chronic pancreatitis. 4. Therapy]. (2010) (0)
- [Role of endothelin in the development of hypertension]. (1989) (0)
- Diagnosis of acinar cell carcinoma using endoscopic ultrasound-guided fine needle aspiration: A case report (2013) (0)
- S1656 CD4+CD25+ Regulatory T Cells Suppress Both TH1- and TH17-Reactions in An Experimental Colitis (2009) (0)
- Tu1147 Acotiamide Has the Potential to Become a Promising Treatment for Patients With Esophagogastric Junction Outflow Obstruction (2015) (0)
- Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (2015) (0)
- Successful preemptive therapy for cerebral multiple hemorrhagic infarctions due to septic embolism by Bacillus cereus after allogeneic hematopoietic stem cell transplantation for acute myelogenous leukemia (2013) (0)
- Selected abstracts from the 14th annual meeting of the Japanese Societies of Hypertension. (1992) (0)
- Tu1877 Different Contractile and Relaxant Effects of Trypsin in Phasic Smooth Muscles of the Esophageal Body and the Tonic Lower Esophageal Sphincter (2014) (0)
- Su1250 Glucagon-Like Peptide-1 Does Not Enhance Inflammatory Responses in Pancreatic Stellate Cells, but Induces Cell Proliferation via ERK Pathway (2012) (0)
- [Current status and problems in the diagnostic criteria for autoimmune pancreatitis]. (2012) (0)
- Mechanism of Action of Atrial Natriuretic Factor in the Adrenal Gland (1989) (0)
- DHEA and the Elderly (2004) (0)
- [Molecular biology of human angiotensin II receptor]. (1993) (0)
- [A case of early recurrence with multiple liver metastases after curative operation of gastric cancer successfully treated by S-1/CDDP combination chemotherapy]. (2008) (0)
- Living donor liver transplantation for acute liver failure caused by acute fatty liver of pregnancy (2010) (0)
- EN BLOC REMOVAL OF A GASTRIC CARCINOID TUMOR USING ENDOSCOPIC SUBMUCOSAL DISSECTION TECHNIQUES (2007) (0)
- [Estimation of indication for living donor liver transplantation in patients with HCV and/or HBV infection]. (2007) (0)
- Tu1157 Preoperative Tissue Sampling of Suspected Gastric Gastrointestinal Stromal Tumors by Mucosal Incision Assisted Biopsy (2012) (0)
- Author's response to reviews Title: No effect modification of serum bilirubin or coffee consumption on the association of gamma-glutamyltransferase with glycated hemoglobin in a cross-sectional study of Japanese men and women Authors: (2012) (0)
- Waist Circumference for the Clinical Diagnosis of Metabolic Syndrome in the Japanese Population: Optimal Cut-Point to Predict Early Arteriosclerosis (2012) (0)
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What Schools Are Affiliated With Ryoichi Takayanagi?
Ryoichi Takayanagi is affiliated with the following schools:
