Steven S. Clark

Q: What Schools Are Affiliated With Steven S. Clark

Steven S. Clark is affiliated with the following schools: Medical University of South Carolina, Massachusetts Institute of Technology, Osaka University

Steven S. Clark's AcademicInfluence.com Rankings

Steven S. Clark

Biology

#9743

World Rank

#12984

Historical Rank

Immunology

#588

World Rank

#607

Historical Rank

biology Degrees

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Biology

Steven S. Clark's Degrees

PhD Immunology Stanford University
Doctorate Medicine University of California, San Francisco

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Steven S. Clark's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes (1989) (2070)
The human hematopoietic colony-stimulating factors. (1987) (1630)
Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. (1990) (1034)
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers (1991) (1013)
Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. (1987) (836)
Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3 (1986) (758)
Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. (1986) (733)
Response of resting human peripheral blood natural killer cells to interleukin 2 (1984) (617)
Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. (1990) (607)
Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator (1985) (527)
Multiple actions of interleukin 6 within a cytokine network. (1988) (511)
Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. (1986) (460)
Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils. (1984) (450)
Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF (1986) (396)
B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes. (1988) (381)
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. (1997) (355)
Human recombinant granulocyte-macrophage colony-stimulating factor: a multilineage hematopoietin. (1985) (354)
Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hematopoietic stem cells: comparison with interleukin-1 alpha. (1988) (338)
Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor. (1989) (334)
B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells. (1987) (330)
Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes. (1986) (278)
Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells (1988) (278)
Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides (1991) (271)
Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. (1988) (271)
Molecular characterization and expression of the gene encoding human erythroid-potentiating activity (1985) (268)
Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages. (1988) (251)
Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture. (1991) (235)
Stimulation of murine hemopoietic colony formation by human IL-6. (1988) (233)
Activation of neutrophils by recombinant interleukin 6. (1989) (225)
Growth factor requirements for survival in G0 and entry into the cell cycle of primitive human hemopoietic progenitors. (1992) (220)
Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor. (1987) (219)
Suppression of in vitro haematopoiesis following human immunodeficiency virus infection (1987) (218)
The effects of three recombinant growth factors, IL-3, GM-CSF, and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture. (1987) (213)
Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibody-dependent cellular cytotoxicity. (1990) (200)
Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults. (1993) (198)
Stimulation of proliferation, differentiation, and function of human cells by primate interleukin 3. (1987) (197)
Molecular characterization of genome of a novel human T-cell leukaemia virus (1983) (191)
Production of hematopoietic colony-stimulating factors by human natural killer cells (1989) (189)
Synergistic factors for stem cell proliferation: further studies of the target stem cells and the mechanism of stimulation by interleukin-1, interleukin-6, and granulocyte colony-stimulating factor. (1988) (178)
Recombinant human granulocyte/macrophage colony-stimulating factor activates intracellular killing of Leishmania donovani by human monocyte-derived macrophages (1987) (174)
A possible autocrine role for interleukin-6 in two lymphoma cell lines. (1989) (173)
Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. (1992) (171)
The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. (1995) (171)
Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. (1987) (166)
Growth regulation of human acute myeloid leukemia: effects of five recombinant hematopoietic factors in a serum-free culture system (1988) (161)
Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. (1985) (159)
Clonal proliferation of murine lymphohemopoietic progenitors in culture. (1992) (158)
Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18. (1998) (143)
Human recombinant granulocyte-macrophage colony stimulating factor and interleukin 3 have overlapping but distinct hematopoietic activities. (1988) (142)
M‐07e human leukemic factor‐dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM‐CSF and IL‐3 (1990) (139)
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. (1987) (136)
Sequence similarity between NKSF and the IL-6/G-CSF family. (1992) (135)
Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. (1987) (134)
Recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor show common biological effects and binding characteristics on human monocytes. (1989) (129)
Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts (1988) (128)
Stage-specific expression of c-kit protein by murine hematopoietic progenitors. (1993) (127)
The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6 (1988) (121)
Effects of hematopoietic growth factors on the survival of primitive stem cells in liquid suspension culture. (1991) (118)
Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. (1990) (117)
Interleukin-6 enhances growth factor-dependent proliferation of the blast cells of acute myeloblastic leukemia. (1988) (116)
Reciprocal inhibition of binding between interleukin 3 and granulocyte-macrophage colony-stimulating factor to human eosinophils. (1989) (112)
Demonstration of burst-promoting activity of recombinant human GM-CSF on circulating erythroid progenitors using an assay involving the delayed addition of erythropoietin. (1985) (111)
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5 (1988) (108)
Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. (1990) (108)
Human P40 T-cell growth factor (interleukin-9) supports erythroid colony formation. (1990) (107)
The effect of recombinant GM-CSF on the recovery of monkeys transplanted with autologous bone marrow. (1987) (104)
Growth of human hemopoietic colonies in response to recombinant gibbon interleukin 3: comparison with human recombinant granulocyte and granulocyte-macrophage colony-stimulating factor. (1987) (104)
Interleukin 1 enhances growth factor-dependent proliferation of the clonogenic cells in acute myeloblastic leukemia and of normal human primitive hemopoietic precursors (1988) (101)
Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. (1989) (100)
Decreased G-CSF and IL-3 Production and Gene Expression from Mononuclear Cells of Newborn Infants (1992) (99)
Recombinant human interleukin-3 stimulation of hematopoiesis in humans: loss of responsiveness with differentiation in the neutrophilic myeloid series. (1988) (97)
The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6. (1988) (94)
Negative regulation of early B lymphopoiesis by interleukin 3 and interleukin 1 alpha. (1994) (92)
Synergistic and antagonistic effects of recombinant human interleukin (IL) 3, IL-1 alpha, granulocyte and macrophage colony-stimulating factors (G-CSF and M-CSF) on the growth of GM-CSF-dependent leukemic cell lines. (1987) (87)
Amplification of IL-2-driven T cell proliferation by recombinant human IL-3 and granulocyte-macrophage colony-stimulating factor. (1988) (87)
Interleukin-11 stimulates multiple phases of erythropoiesis in vitro. (1992) (86)
Human T-cell growth factor: partial amino acid sequence, cDNA cloning, and organization and expression in normal and leukemic cells. (1984) (84)
Structure and expression of genes of GM-CSF and G-CSF in blast cells from patients with acute myeloblastic leukemia. (1988) (84)
Synergistic interaction between interleukin-12 and steel factor in support of proliferation of murine lymphohematopoietic progenitors in culture. (1994) (83)
Growth factor requirement for survival in cell-cycle dormancy of primitive murine lymphohematopoietic progenitors. (1993) (81)
Chimeric mouse tumor models reveal differences in pathway activation between ERBB family– and KRAS-dependent lung adenocarcinomas (2010) (77)
Recombinant gibbon interleukin-3 acts synergistically with recombinant human G-CSF and GM-CSF in vitro. (1988) (75)
The effects of combinations of the recombinant growth factors GM-CSF, G-CSF, IL-3, and CSF-1 on leukemic blast cells in suspension culture. (1988) (68)
Expression cloning of cDNA encoding a novel human hematopoietic growth factor: human homologue of murine T-cell growth factor P40. (1989) (66)
The murine Il-6 gene maps to the proximal region of chromosome 5. (1989) (66)
Erythroid burst-promoting activity of purified recombinant human GM-CSF and interleukin-3: studies with anti-GM-CSF and anti-IL-3 sera and studies in serum-free cultures. (1988) (63)
Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras (1993) (62)
Granulocyte-macrophage colony-stimulating factor is an endogenous regulator of cell proliferation in juvenile chronic myelogenous leukemia. (1989) (60)
Binding of iodinated recombinant human GM-CSF to the blast cells of acute myeloblastic leukemia. (1988) (59)
Interleukin-3 and interleukin-1 alpha allow earlier bone marrow progenitors to respond to human colony-stimulating factor 1. (1988) (58)
The effects of recombinant CSF‐1 on the blast cells of acute myeloblastic leukemia in suspension culture (1988) (57)
Characterization of granulocyte-macrophage colony-stimulating factor receptor on the blast cells of acute myeloblastic leukemia. (1990) (55)
Establishment of a novel heterotransplantable acute lymphoblastic leukemia cell line with a t(17;19) chromosomal translocation the growth of which is inhibited by interleukin-3. (1991) (52)
Human recombinant IL-3 stimulates B cell differentiation. (1989) (49)
Modest stimulatory effect of recombinant human GM-CSF on colony growth from peripheral blood human megakaryocyte progenitor cells. (1987) (48)
Survival of hemopoietic progenitors in the G0 period of the cell cycle does not require early hemopoietic regulators. (1989) (48)
Specific binding, internalization, and degradation of human recombinant interleukin‐3 by cells of the acute myelogenous, leukemia line, KG‐1 (1988) (47)
Studies of thyroglobulin autoantibody synthesis using a micro-ELISA assay. (1982) (47)
Maturation of human acute myeloid leukaemia in vitro; the response to five recombinant haematopoietic factors in a serum‐free system (1989) (43)
De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model. (2009) (43)
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5. (1988) (42)
Recombinant gibbon interleukin‐3 stimulates megakaryocyte colony growth in vitro from human peripheral blood progenitor cells (1988) (40)
Synergistic actions of stem cell factor and other burst-promoting activities on proliferation of CD34+ highly purified blood progenitors expressing HLA-DR or different levels of c-kit protein. (1994) (39)
Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice. (1991) (39)
Crucial Role of the Residue R280 at the F′–G′ Loop of the Human Granulocyte/Macrophage Colony-stimulating Factor Receptor α Chain for Ligand Recognition (1997) (36)
Biological activities of human granulocyte-macrophage colony-stimulating factor. (1988) (35)
Synergistic interaction between interleukin-6 and interleukin-3 in support of stem cell proliferation in culture. (1988) (35)
Interleukin‐6 production by the blast cells of acute myeloblastic leukemia: Regulation by endogenous interleukin‐1 and biological implications (1991) (34)
In vitro production of granulocyte-macrophage colony-stimulating factor in aplastic anemia: possible mechanisms of action of antithymocyte globulin. (1991) (33)
IL-3 inhibits the binding of GM-CSF to AML blasts, but the two cytokines act synergistically in supporting blast proliferation. (1990) (33)
Composition and functional integrity of the in vitro hemopoietic microenvironment in acute myelogenous leukemia: effect of macrophage colony-stimulating factor. (1992) (30)
Additive effects of steel factor and antisense TGF-beta 1 oligodeoxynucleotide on CD34+ hematopoietic progenitor cells. (1994) (29)
Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils. (1990) (29)
Interleukin 6: identification as a hematopoietic colony-stimulating factor. (1988) (28)
Identification through chemical cross-linking of distinct granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors on myeloid leukemic cells, KG-1. (1989) (28)
Interleukin-3: molecular biology and biologic activities. (1989) (27)
In polycythemia vera human interleukin 3 and granulocyte-macrophage colony-stimulating factor enhance erythroid colony growth in the absence of erythropoietin. (1989) (25)
Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets. (1986) (25)
Human interleukin-4 inhibits proliferation of megakaryocyte progenitor cells in culture (1993) (24)
Expression of the CSF‐1 gene in the blast cells of acute myeloblastic leukemia: Association with reduced growth capacity (1988) (24)
Effects of interleukin‐12 on natural killer cell cytotoxicity and the production of interferon‐7 and tumour necrosis factor‐a in patients with myelodysplastic syndromes (1995) (23)
Molecular Determinants of the Granulocyte-Macrophage Colony-stimulating Factor Receptor Complex Assembly* (1999) (22)
Transcriptional modulation of human IL-6 gene expression by verapamil. (1990) (22)
Serum-free culture of enriched hematopoietic progenitors reflects physiologic levels of fetal hemoglobin biosynthesis. (1990) (20)
Basic biology of the hematopoietic growth factors. (1992) (19)
Inhibition of hematopoiesis in normal human long-term marrow cultures treated with recombinant human macrophage colony-stimulating factor. (1991) (19)
Human B cell proliferation in response to IL-4 is associated with enhanced production of B cell-derived growth factors. (1989) (18)
Human interleukin‐9 supports formation of a subpopulation of erythroid bursts that are responsive to interleukin‐3 (1992) (18)
Combinations of stem cell factor with other hematopoietic growth factors enhance growth and sensitivity to cytosine arabinoside of blast progenitors in acute myelogenous leukemia. (1994) (17)
Molecular Cloning of a Primate cDNA and the Human Gene for Interleukin 3 (1988) (17)
Human interleukin-4 inhibits proliferation of megakaryocyte progenitor cells in culture. (1993) (16)
Interleukin-4 as a growth regulator of clonogenic cells in acute myelogenous leukemia in suspension culture. (1991) (16)
Effects of Interleukin-11 on the Proliferation and Cell Cycle Status of Myeloid Leukemic Cells (1993) (16)
Immunogenotypes and clonal culture analysis in B-precursor acute lymphoblastic leukemia. (1992) (13)
Generation of mature CD3+ and T cell receptor (TCR) + T cells from a leukemic analogue of the putative human stem cell by T cell conditioned medium containing IL-3, IL-2, and GM-CSF. (1988) (13)
The structure and dynamics of the granulocyte macrophage colony-stimulating factor receptor defined by the ternary complex model. (1993) (13)
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5 q ( gene mapping / hematopoietic growth factors / chromosomal deletions / malignant transformation ) (12)
Sequential Administration of Interleukin-6 and Granulocyte-Colony Stimulating Factor in Newborn Rats: Modulation of Newborn Granulopoiesis and Thrombopoiesis (1991) (12)
Effect of rhCSF-1 on human hemopoiesis in long-term cultures from patients with acute myelogenous leukemia. (1991) (11)
DEFICIENT T CELL GRANULOCYTE‐MACROPHAGE COLONY STIMULATING FACTOR PRODUCTION IN ALLOGENEIC BONE MARROW TRANSPLANT RECIPIENTS (1990) (10)
Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation. (1990) (9)
The role of interleukin-6 in mitogenic T-cell activation: detection of interleukin-2 heteronuclear RNA by polymerase chain reaction. (1991) (8)
Effects of interferons and interleukin 2 on natural killing of cytomegalovirus-infected fibroblasts. (1987) (8)
Structure of the gene for human interleukin-3 or multi-CSF. (1987) (6)
Molecular cloning and biological characterization of human interleukin-3 (IL-3). (1989) (6)
Human interleukin 3: analysis of the gene and its role in the regulation of hematopoiesis. (1990) (6)
Effects of lethal irradiation and cyclosporin A treatment on the growth and tumoricidal activity of a T cell clone potentially useful in cancer therapy (1995) (5)
Induction of IgE synthesis in anti-IgM-activated nonatopic human B cells by recombinant interleukin-3. (1989) (5)
Thrombopoiesis and thrombopoietin: the significance of "non-Tpo" cytokines. (1996) (5)
Cytokine modulation of the susceptibility of acute T-lymphoblastic leukemia cell lines to LAK activity. (1993) (4)
Autocrine transforming growth factor-β controls G0 phase of early human hematopoietic progenitors in serum- or serum-free culture (1991) (4)
Biological and molecular evidence for the production of IL-6 by human natural killer cells in culture. (1989) (4)
Granulocyte colony-stimulating factors as therapeutic agents. (1992) (3)
Response to IL-18 γ and Produce IFN-T Cell Subsets to Express IL-18 Receptor − CD 8 − , and CD 4 + , CD 8 + Differential Capacities of CD 4 (1998) (3)
Autocrine Transforming Growth-Factor-Beta Controls G0 Phase of Early Human Hematopoietic Progenitors in Serum-Free or Serum-Free Culture (1991) (2)
In vivo hematological effects of seven days of rhIL-6 in neonatal rats. (1992) (2)
Molecular Cloning and Characterization of the Human Gene for Interleukin-3 (IL-3) (1987) (2)
Primate hematopoietic growth factors IL-3 and pharmaceutical compositions (1990) (1)
4868119 Hematopoietic growth factors (1990) (1)
The stem cell mavens had a blast. Second International Symposium on the Molecular Biology of Hematopoiesis, Innsbruck, Austria, July 14-18, 1991. (1992) (1)
Antisense Oligonucleotides for Inhibitors and Tumor-Suppressor Genes Reveal the Hematopoietic Potential of Quiescent Progenitors (1993) (1)
Essai de validation de cible (2006) (0)
A process for producing a polypeptide of primate. (1987) (0)
IL-3 protein, in particular human IL-3, its preparation and use in pharmaceuticals, vector encoding the protein, as well as cells transformed with the vector (1988) (0)
interleukin-6 The myeloid blood cell differentiation-inducing protein MGI-2A is (2011) (0)
Molecular cloning of a primate complementary dna and the human gene for interleukin 3 (1988) (0)
Framstaellning Science purifying lymfokin. (1986) (0)
Human IL-3 protein, pharmaceutical composition containing the protein, vector, coding for the protein, the cell transformed with (1988) (0)
Preparation and Use of IL-6 (1987) (0)
Procedes in vivo de validation du role d'un gene d'entretien tumoral (2003) (0)
A process for producing an IL-6 protein. (1987) (0)
antithymocyte globulin factor in aplastic anemia: possible mechanisms of action of In vitro production of granulocyte-macrophage colony-stimulating (2011) (0)
A process for preparing M-CSF (1988) (0)
Human Granulocyte/Macrophage Colony-stimulating Factor Receptor a Chain for Ligand Recognition (1997) (0)
Family of IP3-like hematopoietic growth factors of primates (1987) (0)
and Produce IFN- T Cell Subsets to Express IL-18 Receptor - CD8 - Differential Capacities of CD4+, CD8+, and CD4 (2013) (0)
Preparation of M-CSF. (1987) (0)
Potential therapeutic uses for hematopoietic colony stimulating factors. (1987) (0)
Biology of growth factors: requirements for stem cell survival. (1991) (0)
Treg GMP isolation for clinical trial in haematopoietic stem cell transplantation: lessons and experience (2011) (0)
Hematopoiesis : proceedings of a UCLA Symposium held at Tamarron, Colorado, February 20-26, 1989 (1990) (0)
Molecular Cloning of the Human CSF Complementary DNAs (2015) (0)
Human cytokine, interleukin-9 (1990) (0)
Chronic Myelogenous Leukemia as a Model System for Stem Cell Growth Regulation and Hematolymphoid Development (1986) (0)
The method of producing a non-human primate IL-3 protein and recombinant protein encoding DNA sequence (1989) (0)
Natural killer cell-stimulation factor (1989) (0)
chromosome 5 The human genes for GM-CSF and IL 3 are closely linked in tandem on (2011) (0)
A process for the treatment of damaged or reduced cells (1993) (0)
Abstract 642: Novel EGFR inhibitory antibodies directed against EGFR mutants with potentially reduced toxicity (2011) (0)
A process for producing m-csf (1987) (0)
A process for the treatment of damaged cells and reduced (1993) (0)
Production et purification de lymphokine (1985) (0)
Process for treating injury or cell decreases. (1993) (0)

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What Schools Are Affiliated With Steven S. Clark?

Steven S. Clark is affiliated with the following schools: