Samuel Donald Wright
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Philosophy Biology
Samuel Donald Wright's Degrees
- PhD Biochemistry Stanford University
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Samuel Donald Wright's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. (1990) (4205)
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2010) (1934)
- NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease (2010) (1887)
- Structure and function of lipopolysaccharide binding protein. (1990) (1716)
- Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14 (1994) (773)
- Soluble CD14 participates in the response of cells to lipopolysaccharide (1992) (746)
- Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies. (1983) (612)
- Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins (1989) (602)
- Gram‐negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction 1 (1991) (552)
- 27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells* (2001) (539)
- Human neutrophil Fc gamma receptor distribution and structure. (1982) (514)
- Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes (1983) (499)
- (d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G* (2005) (489)
- Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen. (1988) (462)
- Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS (1994) (452)
- Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide (1986) (432)
- Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes (1982) (420)
- Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering (2000) (396)
- 11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice (2005) (388)
- Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages (1989) (385)
- Recognition of a bacterial adhesin by an integrin: Macrophage CR3 (α M β 2, CD11b CD18 ) binds filamentous hemagglutinin of Bordetella pertussis (1990) (349)
- Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes (1989) (332)
- Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils (1991) (327)
- Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on lipopolysaccharide binding protein and CD14 (1991) (299)
- Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein (1995) (273)
- Transient adhesion of neutrophils to endothelium (1989) (271)
- Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans. (2006) (268)
- CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide (1989) (266)
- Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family (1991) (265)
- Fibronectin and serum amyloid P component stimulate C3b- and C3bi- mediated phagocytosis in cultured human monocytes (1983) (262)
- Toll, A New Piece in the Puzzle of Innate Immunity (1999) (258)
- Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids. (1997) (251)
- CD14 and innate recognition of bacteria. (1995) (250)
- CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen. (1991) (249)
- Aggregation of complement receptors on human neutrophils in the absence of ligand (1987) (248)
- Role of the adherence-promoting receptors, CR3, LFA-1, and p150,95, in binding of Histoplasma capsulatum by human macrophages (1987) (248)
- Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes (1988) (242)
- Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3* (2003) (238)
- Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (238)
- Guggulsterone Is a Farnesoid X Receptor Antagonist in Coactivator Association Assays but Acts to Enhance Transcription of Bile Salt Export Pump* (2003) (236)
- Role of GPR81 in lactate-mediated reduction of adipose lipolysis. (2008) (224)
- Activation of PPARα or γ Reduces Secretion of Matrix Metalloproteinase 9 but Not Interleukin 8 from Human Monocytic THP-1 Cells (2000) (222)
- Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands. (1989) (218)
- A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease (2017) (218)
- Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14. (1996) (212)
- Deficiency in Inducible Nitric Oxide Synthase Results in Reduced Atherosclerosis in Apolipoprotein E-Deficient Mice (2000) (208)
- Peroxisome Proliferator-activated Receptor-γ Ligands Inhibit Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity* (2001) (206)
- The involvement of CD14 in stimulation of cytokine production by uronic acid polymers (1993) (204)
- Catalytic Properties of Lipopolysaccharide (LPS) Binding Protein (1996) (204)
- Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes. (1986) (204)
- Infectious Agents Are Not Necessary for Murine Atherogenesis (2000) (197)
- Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Inhibit IL-6 or TNF-α Responses of Macrophages to Lipopolysaccharide In Vitro or In Vivo (2000) (195)
- Reduction of Atherosclerosis by the Peroxisome Proliferator-activated Receptor α Agonist Fenofibrate in Mice* (2002) (195)
- High density lipoprotein mediates anti-inflammatory transcriptional reprogramming of macrophages via the transcriptional repressor ATF3 (2013) (193)
- Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact (1997) (192)
- Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites (1986) (189)
- Human neutrophil Fc , , receptor distribution and structure (188)
- Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion (1996) (187)
- The Farnesoid X Receptor Controls Gene Expression in a Ligand- and Promoter-selective Fashion* (2004) (184)
- Neutralization and Transfer of Lipopolysaccharide by Phospholipid Transfer Protein (*) (1996) (184)
- Multiple receptors for endotoxin. (1991) (182)
- Molecules from Staphylococcus aureus that bind CD14 and stimulate innate immune responses (1995) (182)
- Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation* (2007) (179)
- Integrin modulating factor-1: A lipid that alters the function of leukocyte integrins (1992) (169)
- 11β-Hydroxysteroid Dehydrogenase Type 1 Is Induced in Human Monocytes upon Differentiation to Macrophages1 (2001) (167)
- Statins suppress THP‐1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation (2001) (166)
- The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi. (1998) (165)
- Lithocholic Acid Decreases Expression of Bile Salt Export Pump through Farnesoid X Receptor Antagonist Activity* (2002) (160)
- Leukotriene B4 Strongly Increases Monocyte Chemoattractant Protein-1 in Human Monocytes (2004) (154)
- Lipopolysaccharide-binding protein and soluble CD14 transfer lipopolysaccharide to phospholipid bilayers: preferential interaction with particular classes of lipid. (1997) (154)
- C3bi receptor (complement receptor type 3) recognizes a region of complement protein C3 containing the sequence Arg-Gly-Asp. (1987) (149)
- Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells. (1994) (147)
- Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family. (1994) (146)
- Lipophosphoglycan from Leishmania mexicana promastigotes binds to members of the CR3, p150,95 and LFA-1 family of leukocyte integrins. (1990) (141)
- Immunochemotherapy for intracellular Leishmania donovani infection: gamma interferon plus pentavalent antimony. (1988) (136)
- Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages (1985) (135)
- Transport of Bacterial Lipopolysaccharide to the Golgi Apparatus (1999) (135)
- Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation. (1996) (134)
- Identification of a Lipopolysaccharide Binding Domain in CD14 between Amino Acids 57 and 64 (*) (1995) (134)
- Septin: a factor in plasma that opsonizes lipopolysaccharide-bearing particles for recognition by CD14 on phagocytes (1992) (132)
- Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. (1990) (128)
- Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype (2006) (128)
- Phagocytosing macrophages exclude proteins from the zones of contact with opsonized targets (1984) (127)
- Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets. (2004) (122)
- A Potent Synthetic LXR Agonist Is More Effective than Cholesterol Loading at Inducing ABCA1 mRNA and Stimulating Cholesterol Efflux* (2002) (122)
- Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression (2012) (117)
- Ligand specificity of purified complement receptor type three (CD11b/CD18, alpha m beta 2, Mac-1). Indirect effects of an Arg-Gly-Asp (RGD) sequence. (1993) (117)
- Antibody against leukocyte integrin (CD18) prevents reperfusion-induced lung vascular injury. (1990) (115)
- Novel Formulation of a Reconstituted High-Density Lipoprotein (CSL112) Dramatically Enhances ABCA1-Dependent Cholesterol Efflux (2013) (110)
- Induction of 11β-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli (2001) (109)
- Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate* (2001) (109)
- Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration. (1999) (108)
- Regulation of the angiopoietin-like protein 3 gene by LXR Published, JLR Papers in Press, October 16, 2002. DOI 10.1194/jlr.M200367-JLR200 (2003) (106)
- Communication between receptors for different ligands on a single cell: ligation of fibronectin receptors induces a reversible alteration in the function of complement receptors on cultured human monocytes (1984) (105)
- The selective peroxisomal proliferator-activated receptor-gamma agonist has an additive effect on plaque regression in combination with simvastatin in experimental atherosclerosis: in vivo study by high-resolution magnetic resonance imaging. (2004) (100)
- Soluble CD14 Truncated at Amino Acid 152 Binds Lipopolysaccharide (LPS) and Enables Cellular Response to LPS (*) (1995) (97)
- Fibronectin receptor of human macrophages recognizes the sequence Arg- Gly-Asp-Ser (1985) (97)
- Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors* (2007) (95)
- PPARα Agonists Reduce 11β-Hydroxysteroid Dehydrogenase Type 1 in the Liver (2000) (93)
- Does endotoxin stimulate cells by mimicking ceramide? (1995) (91)
- CSL112 Enhances Biomarkers of Reverse Cholesterol Transport After Single and Multiple Infusions in Healthy Subjects (2014) (91)
- CD18-deficient cells respond to lipopolysaccharide in vitro. (1990) (90)
- Potential role of membrane internalization and vesicle fusion in adhesion of neutrophils in response to lipopolysaccharide and TNF. (1996) (88)
- Role of carbohydrate recognition domains of pertussis toxin in adherence of Bordetella pertussis to human macrophages (1992) (88)
- 15-Deoxy-Δ12,1412,14-prostaglandin J2 Inhibits the β2 Integrin-Dependent Oxidative Burst: Involvement of a Mechanism Distinct from Peroxisome Proliferator-Activated Receptor γ Ligation (1999) (88)
- Ontogeny of Fc receptors and complement receptor (CR3) during human myeloid differentiation. (1984) (87)
- Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial (2015) (87)
- Functional characterization of macrophage receptors for in vitro phagocytosis of unopsonized Pseudomonas aeruginosa. (1988) (87)
- Interferon-gamma depresses binding of ligand by C3b and C3bi receptors on cultured human monocytes, an effect reversed by fibronectin (1986) (86)
- Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo. (2000) (85)
- Secretory Leukocyte Protease Inhibitor Interferes with Uptake of Lipopolysaccharide by Macrophages (1999) (85)
- Adamantyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. (2005) (83)
- Simvastatin Reduces Neointimal Thickening in Low-Density Lipoprotein Receptor–Deficient Mice After Experimental Angioplasty Without Changing Plasma Lipids (2002) (80)
- Increased hypercholesterolemia and atherosclerosis in mice lacking both ApoE and leptin receptor. (2005) (79)
- Activation of PPARalpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells. (2000) (77)
- Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i (1986) (76)
- Identification of a Domain in Soluble CD14 Essential for Lipopolysaccharide (LPS) Signaling but Not LPS Binding (*) (1995) (76)
- A multiple ascending dose study of CSL112, an infused formulation of ApoA‐I (2014) (76)
- Tissue factor pathway inhibitor blocks cellular effects of endotoxin by binding to endotoxin and interfering with transfer to CD14. (1997) (76)
- ApoE(-/-) mice develop atherosclerosis in the absence of complement component C5. (2001) (75)
- How complement kills E. coli. I. Location of the lethal lesion. (1981) (75)
- Novel 2,3-dihydrobenzofuran-2-carboxylic acids: highly potent and subtype-selective PPARalpha agonists with potent hypolipidemic activity. (2005) (75)
- Activation of Phagocytic Cells' C3 Receptors for Phagocytosis (1985) (74)
- Inhibitory effect of growth hormone on TNF-alpha secretion and nuclear factor-kappaB translocation in lipopolysaccharide-stimulated human monocytes. (1997) (74)
- Mice Genetically Hyporesponsive to Lipopolysaccharide (LPS) Exhibit a Defect in Endocytic Uptake of LPS and Ceramide (1997) (72)
- Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype. (2006) (72)
- From the bench to the bedside: the future of sepsis research. Executive summary of an American College of Chest Physicians, National Institute of Allergy and Infectious Disease, and National Heart, Lung, and Blood Institute Workshop. (1997) (72)
- A Novel Liver X Receptor Agonist Establishes Species Differences in the Regulation of Cholesterol 7α-Hydroxylase (CYP7a). (2002) (72)
- CD14: Physical Properties and Identification of an Exposed Site That Is Protected by Lipopolysaccharide (*) (1995) (70)
- Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3) (1987) (69)
- Production of matrix metalloproteinase-9 in CaCO-2 cells in response to inflammatory stimuli. (2001) (67)
- A fluorescent cholesterol analog traces cholesterol absorption in hamsters and is esterified in vivo and in vitro. (1999) (65)
- High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists. (2001) (65)
- Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112 (2016) (65)
- Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice. (2016) (65)
- Regulation of lipid metabolism and gene expression by fenofibrate in hamsters. (2001) (64)
- CD14 is involved in control of human immunodeficiency virus type 1 expression in latently infected cells by lipopolysaccharide. (1992) (64)
- Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity. (2001) (62)
- Clustering of ligand on the surface of a particle enhances adhesion to receptor-bearing cells. (1988) (61)
- Pulmonary edema induced by phagocytosing neutrophils. Protective effect of monoclonal antibody against phagocyte CD18 integrin. (1990) (60)
- Critical role of cholesterol ester transfer protein in nicotinic acid-mediated HDL elevation in mice. (2007) (60)
- Discovery of a potent and selective small molecule hGPR91 antagonist. (2011) (59)
- Intestinal absorption of cholesterol is mediated by a saturable, inhibitable transporter. (2000) (56)
- Toll‐like receptor 2 (TLR2) mediates activation of stress‐activated MAP kinase p38 (2002) (56)
- Macrophages form circular zones of very close apposition to IgG-coated surfaces. (1990) (52)
- Chemical characteristics of Staphylococcus aureus molecules that have CD14-dependent cell-stimulating activity. (1996) (51)
- Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib. (2011) (51)
- A Gene Expression Signature That Classifies Human Atherosclerotic Plaque by Relative Inflammation Status (2011) (50)
- A target for cholesterol absorption inhibitors in the enterocyte brush border membrane. (2000) (48)
- Functional analysis of sites within PCSK9 responsible for hypercholesterolemias⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of one figure. Published, JLR Papers in Press, March 19, 2008. (2008) (48)
- Fc receptors on monocytes cause OKT3-treated lymphocytes to internalize T3 and to secrete IL-2. (1986) (47)
- CSL112 (Apolipoprotein A-I [Human]) Enhances Cholesterol Efflux Similarly in Healthy Individuals and Stable Atherosclerotic Disease Patients (2018) (47)
- (2R)-2-Ethylchromane-2-carboxylic Acids: Discovery of Novel PPARα/γ Dual Agonists as Antihyperglycemic and Hypolipidemic Agents (2004) (45)
- Hepatic responses to inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase: a comparison of atorvastatin and simvastatin. (1998) (45)
- Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway. (2002) (45)
- A fluorescence microassay for the quantitation of integrin-mediated adhesion of neutrophil. (1994) (44)
- Identification of the C 3 bi receptor of human monocytes and macrophages by using monoclonal antibodies ( phagocytosis / complement / OKM 1 ) (44)
- Human phagocytes have multiple lipid A-binding sites (1990) (43)
- A Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist Demonstrates Favorable Effects on Lipid Homeostasis (2004) (42)
- Human Kininogen Gene Is Transactivated by the Farnesoid X Receptor* (2003) (42)
- The Amino Acid Residues Asparagine 354 and Isoleucine 372 of Human Farnesoid X Receptor Confer the Receptor with High Sensitivity to Chenodeoxycholate* (2002) (41)
- PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver. (2000) (41)
- Relation of the CD11/CD18 family of leukocyte antigens to the transient neutropenia caused by chemoattractants. (1990) (39)
- Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I. (2008) (39)
- 2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety. (2010) (38)
- Role of Complements C3 and C5 in the Phagocytosis of Liposomes by Human Neutrophils (2004) (37)
- Adhesion-promoting receptors on leukocytes. (1988) (36)
- Soluble CD14 Mediates Efflux of Phospholipids from Cells1 (2001) (36)
- Structure and modulation of Fc and complement receptors. (1984) (36)
- 11β-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature. (2013) (34)
- A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a). (2002) (34)
- Properties of isolated red pulp macrophages from mouse spleen (1988) (33)
- How complement kills E. coli. II. The apparent two-hit nature of the lethal event. (1981) (32)
- Methods for the study of receptor-mediated phagocytosis. (1986) (31)
- Lipopolysaccharide (LPS) binding protein catalyzes binding of LPS to lipoproteins. (1995) (31)
- Effect of human serum and some of its components on neutrophil adherence and migration across an epithelium (1986) (30)
- Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G) Published, JLR Papers in Press, January 9, 2009. (2009) (29)
- MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activities (2004) (29)
- 2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice. (2011) (29)
- 15-Deoxy-Delta12,1412,14-prostaglandin J2 inhibits the beta2 integrin-dependent oxidative burst: involvement of a mechanism distinct from peroxisome proliferator-activated receptor gamma ligation. (1999) (28)
- Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal–Induced Inflammatory Responses by Reducing Complement Activation (2015) (28)
- Fluorogenic substrates for high-throughput measurements of endothelial lipase activity Published, JLR Papers in Press, November 7, 2006. (2007) (28)
- 4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I. (2008) (27)
- Reconstituted HDL Elicits Marked Changes in Plasma Lipids Following Single-Dose Injection in C57Bl/6 Mice (2012) (26)
- Fibrinogen is a component of a novel lipoprotein particle: factor H-related protein (FHRP)-associated lipoprotein particle (FALP). (2000) (24)
- 2-Arylbenzoxazoles as CETP inhibitors: substitution and modification of the alpha-alkoxyamide moiety. (2010) (24)
- Specificity and Regulation of CD18-Dependent Adhesions (1990) (23)
- LPS-dependent interaction of Mac-2-binding protein with immobilized CD14. (1995) (23)
- OKB7, a monoclonal antibody that reacts at or near the C3d binding site of human CR2. (1985) (22)
- A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology. (2007) (21)
- IB4, a monoclonal antibody against the CD18 leukocyte adhesion protein, reduces intracranial pressure following thromboembolic stroke in the rabbit. (1996) (20)
- CD 11 c / CD 18 on neutrophils recognizes a domain at the N terminus of the Aa chain of fibrinogen (19)
- PHAGOCYTOSIS IN CULTURED HUMAN MONOCYTES (1982) (19)
- Binding of Mycobacterium avium-Mycobacterium intracellulare to human leukocytes (1990) (17)
- Reconstituted high‐density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component (2016) (17)
- Cellular strategies in receptor-mediated phagocytosis. (1985) (17)
- 2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy. (2011) (17)
- (2R)-2-methylchromane-2-carboxylic acids: discovery of selective PPARalpha agonists as hypolipidemic agents. (2005) (17)
- A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist demonstrates favorable effects on lipid homeostasis. (2004) (16)
- Design of a novel class of biphenyl CETP inhibitors. (2010) (15)
- Reversible Inactivation of Purified Leukocyte Integrin CR3 (CD11b/CD18, βmβ2) by Removal of Divalent Cations from a Cryptic Site (1995) (15)
- Design and synthesis of potent and subtype-selective PPARα agonists (2006) (15)
- Soluble CD 14 Acts as a Shuttle in the Neutralization of Lipopolysaccharide ( LPS ) by LPS-binding Protein and Reconstituted High Density Lipoprotein (2003) (14)
- A monoclonal antibody to a human neutrophil-specific plasma membrane antigen. Effect of the antibody on the C3bi-mediated adherence by neutrophils and expression of the antigen during myelopoiesis (1988) (13)
- (2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents. (2004) (12)
- Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine. (2002) (12)
- Tissue Factor Pathway Inhibitor Blocks Cellular Effects of Endotoxin by Binding to Endotoxin and Interfering With Transfer to CD 14 (1997) (12)
- Abstract 15780: CSL112, A Novel Formulation of Human Apolipoprotein A-I, Dramatically Increases Cholesterol Efflux Capacity in Patients With Stable Atherothrombotic Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Study (2013) (12)
- Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats. (2011) (12)
- Discovery of substituted biphenyl oxazolidinone inhibitors of cholesteryl ester transfer protein. (2011) (11)
- Pharmacokinetics and Safety of CSL112 (Apolipoprotein A‐I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function (2018) (11)
- Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase. (2012) (11)
- SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors. (2012) (10)
- Deficiency in sPLA(2) does not affect HDL levels or atherosclerosis in mice. (2002) (10)
- Evaluation of potential antiplatelet effects of CSL112 (Apolipoprotein A-I [Human]) in patients with atherosclerosis: results from a phase 2a study (2018) (9)
- CSL112, a novel formulation of human apolipoprotein A-I, dramatically increases cholesterol efflux capacity in healthy subjects: a placebo-controlled, double-blinded, randomized, single ascending dose study (2012) (9)
- MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities. (2004) (9)
- Structure-function relationships in reconstituted HDL: Focus on antioxidative activity and cholesterol efflux capacity. (2017) (9)
- Moderate Renal Impairment Does Not Impact the Ability of CSL112 (Apolipoprotein A‐I [Human]) to Enhance Cholesterol Efflux Capacity (2018) (8)
- A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis. (2009) (8)
- Integrin-Dependent Oxidative Burst: Involvement of a Mechanism Distinct from Peroxisome Proliferator-Activated Receptor g Ligation (1999) (7)
- Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres (2020) (7)
- A novel non-steroidal inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 improves features of metabolic syndrome in murine disease models (2004) (6)
- Circulating HDL levels control hypothalamic astrogliosis via apoA-I[S] (2018) (6)
- Reversible inactivation of purified leukocyte integrin CR3 (CD11b/CD18, alpha m beta 2) by removal of divalent cations from a cryptic site. (1995) (6)
- Serum levels of soluble CD14 in allergic inflammation (1998) (5)
- Human Leukocyte Elastase Is an Endogenous Ligand for the Integrin CR 3 ( C D l l b / C D 1 8 , Mac-l , c ~ [ 32 ) and Modulates Polymorphonuclear Leukocyte Adhesion (2003) (5)
- Bis-aryl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. (2008) (5)
- Infusion of CSL112, a novel formulation of human apolipoprotein A-I, in healthy subjects removes tissue cholesterol and directs its clearance (2013) (4)
- Pharmacometric analyses to characterize the effect of CSL112 on apolipoprotein A‐I and cholesterol efflux capacity in acute myocardial infarction patients (2020) (4)
- Peroxisome Proliferator-activated Receptor- g Ligands Inhibit Adipocyte 11 b -Hydroxysteroid Dehydrogenase Type 1 Expression and Activity* (2001) (4)
- Editorial overview Fatal attraction: recognition and killing mechanisms in innate immunity (1993) (3)
- Regulation of the function of receptors for C3b and C3bi on human mononuclear phagocytes by receptors for other ligands (1985) (3)
- Abstract 16500: CSL112 Restores Cholesterol Efflux in Patients Immediately After Acute Myocardial Infarction (2017) (3)
- CSL112, A NOVEL FORMULATION OF HUMAN APOA-I, RAPIDLY ACTIVATES LECITHIN-CHOLESTEROL ACYLTRANSFERASE UPON INFUSION INTO RABBITS AND MONKEYS (2012) (3)
- Abstract 11851: CSL112, a Novel Formulation of Human Apolipoprotein A-I, Provides Sustained Increases in Biomarkers of Cholesterol Transport Following Repeat Dosing: A Placebo-Controlled, Randomized Multiple Ascending Dose Study in Healthy Subjects (2012) (3)
- ApoA-I Infusion Therapies Following Acute Coronary Syndrome: Past, Present, and Future (2022) (2)
- P1106Direct augmentation of cholesterol efflux capacity in AMI patients: a PKPD substudy of AEGIS-I (2017) (2)
- Title : Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (2)
- 2.P.24 Responses to the inhibition of HMG-CoA reductase: A comparison of simvastatin and atorvastatin (1997) (2)
- 27 Hepatic responses to inhibition of HMG-CoA reductase: a comparison of atorvastatin and simvastatin (1997) (2)
- Design and synthesis of potent and subtype-selective PPARalpha agonists. (2006) (2)
- Abstract 10220: CSL112 (Apolipoprotein A-I (human)) Infusion Rapidly Increases ApoA-I Exchange Rate via Specific Serum Amyloid-Poor HDL Sub-Populations When Administered to Patients Post Myocardial Infarction (2021) (1)
- Abstract 10491: CSL112 Suppresses Inflammation in Human Monocyte-Derived Macrophages (2021) (1)
- CSL112 (Apolipoprotein A-I [Human]) Strongly Enhances Plasma Apoa-I and Cholesterol Efflux Capacity in Post-Acute Myocardial Infarction Patients: A PK/PD Substudy of the AEGIS-I Trial (2022) (1)
- Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346] (2010) (1)
- Recognition and binding of pathogenic yeasts by adhesion molecules of human macrophages. (1988) (1)
- Abstract 11838: CSL112, a Novel Formulation of Apolipoprotein A-I Exhibits Potent Anti-Inflammatory Activity in Whole Blood (2012) (1)
- Abstract 15370: Mechanism of High Density Lipoprotein Remodeling Induced by CSL112 (2014) (1)
- PPAR γ-agonist induces regression of atherosclerotic plaques: invivo study by high resolution magnetic resonance imaging (2002) (1)
- Septin, an activity in plasma that enables CD14-dependent recognition of LPS. (1994) (1)
- Abstract 502: CSL112, a Novel Formulation of Human ApoA-I, Enhances the Capacity of Serum to Efflux Cholesterol from Macrophages (2012) (1)
- Nicotinic Acid Receptor Agonists Differentially Activate (2007) (1)
- Co-administration of CSL112 (apolipoprotein A-I [human]) with atorvastatin and alirocumab is not associated with increased hepatotoxic or toxicokinetic effects in rats. (2021) (1)
- Human ACCATTTATAAC AGAGGTGAACAT ACAAG CCTGATATAACA TCACAGTAGACA TGAAAA TGTATGCCATCAG ACCCAGCAACTCT CA Angptl 3 Mouse GATTTGCTATGT TGGATGATGTCAA CTTATGGACAAAA TCTTTAAGTCCA TGA ATTTTAGCGAATG GCCTCCTGCAGCT CYP 7 A Mouse CAAAACCTCCAA TCTGTCATGAGA GCGTTAGATATC CGGCTTCAAA (2002) (0)
- Regulation of leukocyte integrins (1992) (0)
- Abstract 430: A Novel Nonradioactive Method Documents Strong Elevation of the Cholesterol Esterification Rate by CSL112, a Novel Formulation of Human Apolipoprotein A-I (2014) (0)
- Differentiation to Macrophages Induced in Human Monocytes upon-Hydroxysteroid Dehydrogenase Type 1 Is β 11 (2001) (0)
- Cytotoxicity to tumor cells of peripheral blood monocytes from patients with superficial bladder cancer treated with intravesical bcg (1984) (0)
- Cholesterol absorption: Mechanisms and inhibitors (2000) (0)
- This information is current as Health and Disease Scavenger Receptors and Their Roles in A Consensus Definitive Classification of (2017) (0)
- Biological basis and proposed mechanism of action of CSL112 (Apolipoprotein A-I [Human]) for prevention of major adverse cardiovascular events in patients with myocardial infarction. (2021) (0)
- Abstract 831: Functional Analysis of S127 and D374 Residues of PCSK9: Distinct Hot Spots for Gain of Function (2007) (0)
- Inflammasome (WS-078) Chairpersons: Shun'ichiro Taniguchi, Takashi Suda (2010) (0)
- Abstract 15426: CSL112 Enhances Cholesterol Efflux Equally in Patients with High and Low High Density Lipoprotein Functionality (2014) (0)
- Inhibition of white blood cells from flowing in organ in septicemia or other traumatic injury (1989) (0)
- Innate recognition of bacterial LPS (1999) (0)
- Structure-function relationships across reconstituted HDL: Focus on antioxidative activity (2014) (0)
- IDENTIFICATION OF THE LIPOPOLYSACCHARIDE (LPS) BINDING SITE OF LPS BINDING PROTEIN (LBP) BY SITE‐DIRECTED MUTAGENESIS, EVIDENCE FOR A SIMILAR LPS RECOGNITION MECHANISM IN DIFFERENT LPS BINDING PROTEINS: 85 (1997) (0)
- vasculatureproinflammatory gene expression in the -HSD1 inhibition reduces atherosclerosis in mice by (2015) (0)
- Abstract 13218: Remodeling of High Density Lipoprotein Induced by CSL112: Structure and Function of the Remodeled Lipoproteins (2016) (0)
- Association de medicaments anti-hypercholesterolemique (2001) (0)
- A pharmaceutical composition for inhibiting tilstoemningen of leukocytes to organs during sepsis or other trauma (1989) (0)
- Metoder Science Foer foerhindrande The compositions of the symtomer of sepsis. (1992) (0)
- Method Foer Inhibition of intraede of leukocyter i organ e.g. at blodfoergiftning. (1989) (0)
- Serum levels of soluble CD 14 in allergic inflammation (1998) (0)
- Abstract 17135: Distribution of Anti-oxidative Activity During Remodeling of High Density Lipoprotein: Studies With CSL112 (2015) (0)
- Afamin: similar to human serum albumin protein. (1995) (0)
- Integrin Modulating Factor and the Regulation of Leukocyte Integrins (1994) (0)
- Abstract 403: Generation of PreBeta1 High Density Lipoprotein by CSL112 in Human Plasma (2013) (0)
- 63 : Investigating the anti-inflammatory effects of HDL in macrophages (2013) (0)
- CSL112, A NOVEL FORMULATION OF HUMAN APOA-I, ROBUSTLY ENHANCES THE ABILITY OF SERUM TO EFFLUX CHOLESTEROL (2012) (0)
- Complement dependency of cholesterol crystal-induced inflammation – II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP) (2012) (0)
- Circulating HDL levels control hypothalamic astrogliosis via apoA-I. Papers in Press, July 10, 2018 DOI https://doi.org/10.1194/jlr.M085456 (2018) (0)
- Method and compositions that improve the symptoms of sepsis. (1990) (0)
- CSL112 ENHANCES THE ABILITY OF SERUM TO EFFLUX CHOLESTEROL IN PATIENTS WITH MODERATE RENAL IMPAIRMENT (2017) (0)
- CSL112 Enhances Cholesterol Efflux Equally in Patients with High and Low HDL Functionality (2014) (0)
- CSL112, A NOVEL FORMULATION OF HUMAN APOA-I, RAPIDLY ENHANCES CHOLESTEROL EFFLUX CAPACITY OF PLASMA FOLLOWING INFUSION (2012) (0)
- Special methods for measuring phagocytosis (1986) (0)
- Reconstituted high density lipoprotein formulation and method for preparing the (2011) (0)
- Apolipoprotein E-Deficient Mice Results in Reduced Atherosclerosis in Deficiency in Inducible Nitric Oxide Synthase (2000) (0)
- Adhesion-promoting receptors on phagocytes. (1991) (0)
- CSL112 (Human Apolipoprotein A-I) Infusion Rapidly Increases APOA1 (Apolipoprotein A1) Exchange Rate via Specific Serum Amyloid-Poor HDL (High-Density Lipoprotein) Subpopulations When Administered to Patients Post-Myocardial Infarction. (2023) (0)
- RoleofCarbohydrate Recognition DomainsofPertussis Toxinin Adherence ofBordetella pertussis toHumanMacrophages (1992) (0)
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What Schools Are Affiliated With Samuel Donald Wright?
Samuel Donald Wright is affiliated with the following schools:
