Stephan E. Mergenhagen
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Philosophy Biology
Stephan E. Mergenhagen's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Immunology Stanford University
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Stephan E. Mergenhagen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). (1981) (571)
- Bone Resorbing Activity in Supernatant Fluid from Cultured Human Peripheral Blood Leukocytes (1972) (532)
- Inflammatory and immunomodulatory roles of TGF-β (1989) (435)
- Macrophages as a source of tumoricidal activity (tumor-necrotizing factor) (1980) (382)
- Macrophage- and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome (1991) (311)
- Effect of virus infections on the function of the immune system. (1970) (302)
- Collagenase production by endotoxin-activated macrophages. (1974) (281)
- INTERACTIONS OF THE COMPLEMENT SYSTEM WITH ENDOTOXIC LIPOPOLYSACCHARIDE: CONSUMPTION OF EACH OF THE SIX TERMINAL COMPLEMENT COMPONENTS (1968) (272)
- Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors. (1972) (265)
- Collagenase production by lymphokine-activated macrophages. (1975) (256)
- Physical, chemical, and immunological properties of lipopolysaccharide released from Escherichia coli by ethylenediaminetetraacetate. (1968) (238)
- The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxim. (1980) (218)
- INTERACTIONS OF THE COMPLEMENT SYSTEM WITH ENDOTOXIC LIPOPOLYSACCHARIDE (1968) (214)
- Prostaglandin regulation of macrophage collagenase production. (1977) (211)
- Macrophage activation by mycobacterial water soluble compounds and synthetic muramyl dipeptide. (1979) (203)
- Increased thymocyte-activating factor in human gingival fluid during gingival inflammation (1982) (178)
- A human mononuclear leukocyte chemotactic factor: characterization, specificity and kinetics of production by homologous leukocytes. (1973) (171)
- BIOLOGICAL ACTIVITY OF COMPLEMENT IN VIVO ROLE OF C5 IN THE ACCUMULATION OF POLYMORPHONUCLEAR LEUKOCYTES IN INFLAMMATORY EXUDATES (1971) (167)
- Complement-Dependent Stimulation of Prostaglandin Synthesis and Bone Resorption (1974) (165)
- A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin. (1969) (160)
- Polymorphonuclear Leukocyte Chemotactic Activity in Rabbit Serum and Guinea Pig Serum Treated with Immune Complexes: Evidence for C5a as the Major Chemotactic Factor (1970) (149)
- Preparation and biological activities of endotoxins from oral bacteria. (1961) (140)
- Factors from saliva and oral bacteria, chemotactic for polymorphonuclear leukocytes: their possible role in gingival inflammation. (1970) (134)
- ULTRASTRUCTURE OF VEILLONELLA AND MORPHOLOGICAL CORRELATION OF AN OUTER MEMBRANE WITH PARTICLES ASSOCIATED WITH ENDOTOXIC ACTIVITY (1964) (126)
- Macrophage-lymphocyte synergy in the production of osteoclast activating factor. (1974) (118)
- The complement profile in acute glomerulonephritis systemic lupus erythematosus and hypocomplementemic chronic glomerulonephritis. Contrasts and experimental correlations. (1968) (118)
- Adhesion molecules as regulators of mast-cell and basophil function. (1994) (108)
- Tyrosine phosphorylation of pp125FAK by the aggregation of high affinity immunoglobulin E receptors requires cell adherence. (1993) (108)
- Significance of complement to the mechanism of action of endotoxin. (1969) (104)
- Studies on synergistic infections. I. Experimental infections with anaerobic streptococci. (1958) (104)
- Adherence of rat basophilic leukemia (RBL-2H3) cells to fibronectin-coated surfaces enhances secretion. (1992) (103)
- Bactericidal antibody in mammalian serum to obligatorily anaerobic Gram-negative bacteria. (1966) (102)
- A Role for Cell-Mediated Immunity in the Pathogenesis of Periodontal Disease. (1974) (102)
- Inflammatory and immunomodulatory roles of TGF-beta. (1989) (98)
- Autocrine and paracrine regulation of astrocyte function by transforming growth factor-β (1992) (96)
- Importance of Actinomyces and certain gram-negative anaerobic organisms in the transformation of lymphocytes from patients with periodontal disease (1976) (93)
- Resistance of macrophages from C3H/HeJ mice to the in vitro cytotoxic effects of endotoxin. (1977) (92)
- Blastogenesis and Lymphokine Synthesis by T and B Lymphocytes from Patients with Periodontal Disease (1974) (89)
- INTERACTIONS OF THE COMPLEMENT SYSTEM WITH THE SURFACE AND ENDOTOXIC LIPOPOLYSACCHARIDE OF VEILLONELLA ALCALESCENS (1967) (87)
- Apoptosis in human monocytes: possible role in chronic inflammatory diseases. (1993) (83)
- Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens (1979) (82)
- Generation and characterization of a lipopolysaccharide-induced and serum-derived cytotoxic factor for tumor cells (1980) (78)
- ELEVATED γ-GLOBULIN AND INCREASED ANTIBODY PRODUCTION IN MICE INFECTED WITH LACTIC DEHYDROGENASE VIRUS (1966) (73)
- Protein tyrosine phosphorylation as a mechanism of signalling in mast cells and basophils. (1995) (72)
- Gingivitis and oral ulceration in patients with neutrophil dysfunction. (1985) (70)
- Differential regulation of colony-stimulating factors and interleukin 2 production by cyclosporin A. (1987) (65)
- Humoral mediators of chemotaxis of mononuclear leukocytes. (1972) (65)
- Cell adherence to fibronectin and the aggregation of the high affinity immunoglobulin E receptor synergistically regulate tyrosine phosphorylation of 105-115-kDa proteins. (1993) (64)
- Thymocyte Activating Factor(s) in Human Gingival Fluids (1984) (63)
- Inhibition of Cellular Immune Reactions in Mice infected with Lactic Dehydrogenase Virus (1969) (63)
- Elaboration of lymphotoxin by cultured human peripheral blood leucocytes stimulated with dental-plaque deposits. (1973) (62)
- Chemotaxis of Macrophages (1976) (62)
- Lesions in Escherichia coli membranes after action of antibody and complement (1966) (61)
- Lymphokine production by C3b-stimulated B cells. (1975) (61)
- A cell surface glycoprotein of rat basophilic leukemia cells close to the high affinity IgE receptor (Fc epsilon RI). Similarity to human melanoma differentiation antigen ME491. (1991) (59)
- Defective prostaglandin synthesis by C3H/HeJ mouse macrophages stimulated with endotoxin preparations (1979) (58)
- Type 2 fimbrial lectin-mediated phagocytosis of oral Actinomyces spp. by polymorphonuclear leukocytes (1986) (58)
- ANTIBODY TO LEPTOTRICHIA BUCCALIS IN HUMAN SERA. (1965) (57)
- HISTOPATHOLOGIC EFFECTS OF ENDOTOXIN INJECTED INTO RABBIT ORAL MUCOSA. (1964) (54)
- Influence of Scurvy and Lathyrism (Odoratism) on Hydroxyproline Excretion (1961) (53)
- Lipopolysaccharide (LPS) regulation of the immune response: T lymphocytes from normal mice suppress mitogenic and immunogenic responses to LPS. (1980) (52)
- Interactions of the Complement System with Native and Chemically Modified Endotoxins (1968) (51)
- Significant contribution of spleen cells in mediating the lethal effects of endotoxin in vivo (1976) (51)
- The rat mast cell antigen AD1 (homologue to human CD63 or melanoma antigen ME491) is expressed in other cells in culture. (1992) (51)
- Interactions of the complement system with endotoxic lipopolysaccharide: the generation of an anaphylatoxin. (1969) (51)
- In vitro studies of a chemotactic lymphokine in the guinea pig. (1974) (51)
- Inhibitors of reactive oxygen intermediates suppress bacterial cell wall-induced arthritis. (1991) (49)
- Mineralization of Bacteria (1962) (49)
- IMMUNOCHEMICAL ANALYSIS OF HUMAN ORAL STRAINS OF FUSOBACTERIUM AND LEPTOTRICHIA (1963) (48)
- Mouse 3T3 fibroblasts induce rat basophilic leukemia (RBL-2H3) cells to acquire responsiveness to compound 48/80. (1993) (48)
- The aggregation of the high affinity IgE receptor induces tyrosine phosphorylation of paxillin, a focal adhesion protein. (1994) (47)
- Decreased properdin activity in acute glomerulonephritis. (1969) (46)
- Complement-dependent biological functions in complement deficiency in man. (1966) (46)
- Initiation of bone resorption by the classical and alternative C pathways and its mediation by prostaglandins. (1977) (46)
- Activation of complement by endotoxin. (1973) (46)
- Molecular basis of bacterial adhesion in the oral cavity. (1987) (45)
- Calcification in vivo of implanted collagen. (1960) (45)
- Interaction of soluble C3 fragments with guinea pig lymphocytes. Comparison of effects of C3a, C3b, C3c, and C3d on lymphokine production and lymphocyte proliferation. (1976) (44)
- Superoxide release and superoxide dismutase expression by human gingival fibroblasts. (2000) (44)
- Decreased C'-1q protein concentration and agglutinating activity in agammaglobulinaemia syndromes: an inborn error reflected in the complement system. (1968) (44)
- Prostaglandin regulation of colony-stimulating factor production by lipopolysaccharide-stimulated murine leukocytes (1979) (43)
- An in vitro study of neutrophils obtained from the normal gingival sulcus. (1982) (42)
- Inhibition of phospholipase activity in human monocytes by IFN-gamma blocks endogenous prostaglandin E2-dependent collagenase production. (1990) (42)
- Nature and Significance of Somatic Antigens of Oral Bacteria (1967) (41)
- Mechanism of lipopolysaccharide-induced tumor necrosis: requirement for lipopolysaccharide-sensitive lymphoreticular cells (1979) (41)
- Separation of a serum-derived tumoricidal factor from a helper factor for plaque-forming cells. (1980) (41)
- Molecular basis of oral microbial adhesion : proceedings of a workshop held in Philadelphia, Pennsylvania, 5-8 June 1984 (1985) (37)
- Differential endotoxin sensitivity of lymphocytes and macrophages from mice with an X-linked defect in B cell maturation. (1978) (35)
- Adjuvanticity of lactic dehydrogenase virus: influence virus infection on the establishment of immunologic tolerance to a protein antigen in adult mice. (1967) (35)
- INTERACTIONS OF THE COMPLEMENT SYSTEM WITH ENDOTOXIC LIPOPOLYSACCHARIDES IN IMMUNOGLOBULIN-DEFICIENT SERA (1970) (35)
- Activation of complement by endotoxin: a role for 2 globulin, C1, C4 and C2 in the consumption of terminal complement components by endotoxin-coated erythrocytes. (1972) (33)
- Occurrence of Natural Antibacterial Antibody in Human Parotid Fluid (1965) (32)
- Reconstitution of High Affinity IgE Receptor-mediated Secretion By Transfecting Protein Tyrosine Kinase pp125FAK * (1997) (32)
- Complement as a mediator of inflammation: formation of biologically-active products after interaction of serum complement with endotoxins and antigen-antibody complexes. (1970) (31)
- The immune response in rabbits to bacterial somatic antigen administered via the oral mucosa. (1969) (31)
- A SYNTHETIC GLYCOLIPID WITH B-CELL MITOGENIC ACTIVITY (1974) (30)
- Stimulation of human monocytes by endotoxin-associated protein: inhibition of programmed cell death (apoptosis) and potential significance in adjuvanticity (1992) (30)
- Studies on an endotoxin of a group C Neisseria meningitidis. (1963) (30)
- Genetic control of in vivo sensitivity to lipopolysaccharide: evidence for codominant inheritance. (1979) (28)
- Histamine-Releasing Factor Generated by the Interaction of Endotoxin with Hamster Serum (1970) (28)
- Experimental infections with oral spirochetes. (1961) (28)
- Microenvironmental Factors that Influence Mast Cell Phenotype and Function (1992) (27)
- Action of endotoxin on lymphoid cells. (1977) (26)
- Susceptibility of Conventional and Germfree Mice to Lethal Effects of Endotoxin (1963) (26)
- Comparative Immunology of the Oral Cavity (1971) (26)
- Complement as a Mediator of the Inflammatory Response: Interaction of Complement with Mammalian and Bacterial Enzymes (1972) (25)
- Interactions of the complement system with endotoxins from a Salmonella minnesota mutant deficient in O-polysaccharide and heptose. (1968) (25)
- Role of lipopolysaccharide in regulating colony-stimulating factor-dependent macrophage proliferation in vitro. (1980) (24)
- Failure of Endotoxin to Protect C3H/HeJ Mice Against Lethal X-Irradiation (1977) (24)
- Enhanced humoral immunity in mice infected with attenuated Venezuelan equine encephalitis virus. (1969) (24)
- A 77-kDa Protein Associates with pp125FAK in Mast Cells and Becomes Tyrosine-phosphorylated by High Affinity IgE Receptor Aggregation (*) (1995) (23)
- Serologically specific lipopolysaccharides from oral veillonella. (1963) (23)
- Electron microscopic localization of endotoxic lipopolysaccharide in gram-negative organisms. (1966) (23)
- Lysis of reconstituted collagen and catabolism of products of collagenolysis by the oral microbiota (1960) (22)
- Experimental intracutaneous fusobacterial and fusospirochetal infections. (1963) (21)
- PROSTAGLANDIN AND CYCLIC AMP REGULATION OF MACROPHAGE INVOLVEMENT IN CONNECTIVE TISSUE DESTRUCTION (1979) (21)
- From the National Institute of Dental Research: summary of a workshop on leukocyte function in bacterial diseases with an emphasis on periodontal disease. (1979) (21)
- Endotoxic Properties of Oral Bacteria as Revealed by the Local Shwartzman Reaction (1960) (20)
- The relationship of complement consumption to immune fever. (1971) (20)
- Inhibition of allergic reactions with monoclonal antibody to the high affinity IgE receptor. (1988) (20)
- Prolongation of skin homografts by rabbit anti-mouse lymphocyte serum in mice rendered tolerant to rabbit gamma-globulin. (1968) (19)
- Induction of granulocyte-macrophage colony-stimulating factor by lipopolysaccharide and anti-immunoglobulin M-stimulated murine B cell lines. (1987) (18)
- Mast cells and their microenvironment: the influence of fibronectin and fibroblasts on the functional repertoire of rat basophilic leukemia cells. (1993) (17)
- Relation of ionizing groups to the structure of the collagen fibril. (1961) (16)
- Partial purification of a bone-resorbing factor elaborated from human allogeneic cultures. (1979) (15)
- Resistance of C3H/HeJ Mice to Lethal Challenge with Herpes Simplex Virus (1978) (15)
- Measurement of antibody against human IgG by the neutralization of IgG-sensitized herpes simplex virus. (1970) (15)
- Immunological and chemical studies on an oral Veillonella endotoxin. (1962) (15)
- Consumption of hamster complement by bacterial endotoxin. (1970) (15)
- Polysaccharide-Lipid Complexes from Veillonella parvula (1965) (14)
- Effect of C4 depletion on the utilization of the terminal components of guinea-pig complement by endotoxin. (1971) (14)
- Further Characterization of a Factor From Endotoxin-Treated Serum which Releases Histamine and Heparin from Mast Cells (1972) (14)
- Kupffer Cells Express Type I TGF-β Receptors, Migrate to TGF-β and Participate in Streptococcal Cell Wall Induced Hepatic Granuloma Formation (1992) (13)
- Defective responses to lipid A in C3H/HeJ mice: approaches to an understanding of lipid A-cell interaction. (1984) (13)
- Regulation of monocyte/macrophage collagenase. (1988) (13)
- Immune fever in the rabbit: responses of the hematologic and complement systems. (1971) (13)
- PROPERTIES OF A LYSOZYME-DISSOCIATED ENDOTOXIC FRACTION FROM ESCHERICHIA COLI (1964) (12)
- Differences in susceptibility to herpes simplex virus infection of inbred strains of mice. (1978) (12)
- Granulocyte-macrophage colony-stimulating factor regulation in murine T cells and its relation to cyclosporin A. (1988) (12)
- Inhibition of cellular immunity and enhancement of humoral antibody formation in mice infected with lactic dehydrogenase virus. (1969) (12)
- Spirochaetal abscesses in hamster cheek pouch. (1961) (12)
- B lymphocyte derived hematopoietic growth factors. (1989) (11)
- INFLUENCE OF ENDOTOXIN ON RESISTANCE OF MICE TO INTRAPERITONEAL INFECTION WITH HUMAN ORAL BACTERIA. (1964) (10)
- The mechanism of basophil histamine release in patients with periodontal disease. (1978) (10)
- Immunological comparison of plaque-resistant and plaque-susceptible inbred rat strains. (1981) (10)
- BIOLOGICAL ACTIVITY OF COMPLEMENT IN VIVO (1971) (9)
- Studies on Mucopolysaccharase Activity of Oral Spirochetes (1959) (9)
- Specific Induced Resistance of Mice to Endotoxin (1962) (9)
- Host-parasite interactions in periodontal diseases : proceedings of a symposium held at Buffalo, New York, 4-6 May, 1981 (1982) (8)
- INFLUENCE OF ENDOTOXIN ON THE DERMAL RESPONSE OF RABBITS TO HUMAN ORAL BACTERIA. (1964) (8)
- Studies on the penetration of schistosome cercariae. I. Action of the antihistamine promethazine hydrochloride. (1960) (7)
- The sialic acid content of human saliva. (1961) (7)
- NUTRITIONAL PATTERNS OF SOME ANAEROBIC STREPTOCOCCI (1957) (7)
- A role for cell-mediated immunity in the pathogenesis of periodontal disease. (1974) (6)
- Kupffer cells express type I TGF-beta receptors, migrate to TGF-beta and participate in streptococcal cell wall induced hepatic granuloma formation. (1992) (6)
- A role for cell-mediated immunity in the pathogenesis of periodontal disease. (1974) (6)
- Induction of tolerance in immunologically competent primates. (1969) (5)
- The Role of Post-Endotoxin Serum Components from BCG Infected Mice in the Protection of Compromised Hosts (1986) (5)
- Suppression of lymphocyte and fibroblast proliferation by Actinomyces viscosus-activated murine macrophages. (1987) (5)
- Mechanism of adjuvant activity of dental plaque: in vitro activation of residual helper T-cell precursors in T-cell-deficient murine spleen cell cultures (1977) (5)
- STIMULATION OF RESISTANCE TO INFECTION BY LIPOID DERIVED FROM NEISSERIA MENINGITIDIS ENDOTOXIN. (1963) (5)
- Passive haemagglutination for estimation of early and late anti-human gamma-globulin antibodies. (1966) (5)
- Lysis by Human Oral Bacteria of Collagen Altered By Ethylene Oxide (1960) (5)
- Mediator interactions regulating macrophage secretion of interleukin 1 and interferon. (1983) (5)
- Biological Consequences of Endotoxin Interaction with Complement (1975) (4)
- Studies on the significance of local hypersensitivity in periodontal disease. (1965) (4)
- Spreading Factor Activity of Bacterial Chondroitinase.∗ (1958) (3)
- THE BACTERIAL FLORA OF THE COMMON GARTERSNAKE, THAMNOPHIS SIRTALIS SIRTALIS (1956) (3)
- Stimulation of Prostaglandin Synthesis with Resultant Bone Resorption by the Classical and Alternative C Pathways (1976) (2)
- Role of c5 in the accumulation of polymorphonuclear leukocytes (pmns) in mice treated with endotoxin. Abstr. (1971) (2)
- In vitro and in vivo effects of anti-tumor antibody covalently coupled to a chemotactic peptide. (1983) (2)
- Chronic Adult Periodontitis (1988) (2)
- Effect of Certain Amino Acids and Peptides on Hyaluronidase Production by Staphylococcus aureus ∗ (1958) (2)
- Synergistic action of lipopolysaccharide and tumor-promoting phorbol esters: two-signal requirement for colony-stimulating factor production by murine bone marrow cells. (1986) (2)
- Human Mononuclear Leukocyte Chemotaxis: Definition of Two Chemotactic Factors and a Previously Unrecognized Immune Dysfunction (1973) (1)
- Production of Colony-Stimulating Factor (CSF) by Bone Marrow Cells Stimulated with Lipopolysaccharide (LPS) and Phorbol Esters (1986) (1)
- Leukocyte chemotactic activity from oral bacteria. (1969) (1)
- VIRUS-MACROPHAGE-LYMPHOCYTE INTERACTIONS (1977) (1)
- Transformation of Mouse B-Lymphocytes by the Lipid Component of Endotoxin (1975) (1)
- STUDIES ON SYNERGISTIC INFECTIONS. II. DISAGGREGATION OF GROUP SUBSTANCE IN ROOSTER WATTLE INFECTIONS. (1964) (0)
- Prostaglandin regulation of macrophage collagenase production ( endotoxin / macrophage activation / prostaglandin synthesis / connective tissue ) (0)
- Stimulation ofHumanMonocytes byEndotoxin-Associated Protein: Inhibition ofProgrammed CellDeath(Apoptosis) and Potential Significance inAdjuvanticity (1992) (0)
- MICROBIOLOGY 1975: cellular basis of adjuvanticity (1975) (0)
- Role of Liver Macrophages (Kupffer Cells) in Bacterial Cell Wall-Induced Hepatic Inflammation (1993) (0)
- Induction of tolerance for ALG. (1969) (0)
- ALTERATIONS IN TYPE AND BACTERICIDAL ACTIVITY OF MOUSE PERITINEAL PHAGOCYTES AFTER INTRAPERITONEAL ADMINISTRATION OF ENDOTOXIN. (1964) (0)
- Differential Patterns of C3b Receptor Expression on Guinea Pig Macrophages (1978) (0)
- Contents, Vol. 36, 1969 (1969) (0)
- CHARACTERIZATION OF A CYTOTOXIC SERUM FACTOR FROM MICE - MODE OF PRODUCTION, SPECIFICITY AND PHYSICOCHEMICAL PROPERTIES (1979) (0)
- The mechanism of lipopolysaccharide induced adjuvanticity: Cellular and molecular basis (1979) (0)
- __roles of TGF-13 (1989) (0)
- Summary Comments on Cellular Antigens of Gram-Negative Bacteria (1972) (0)
- Polymorphonuclear Leukocyte Chemotactic Activity (2003) (0)
- COMMUNICATIONS (1968) (0)
- In memoriam Dr. J. R. Frey. (1974) (0)
- Genetic control of macrophage sensitivity to endotoxin in vitro. Abstr. (1978) (0)
- LPS REGULATION OF THE IMMUNE RESPONSE: CELLULAR AND MOLECULAR BASIS OF ADJUVANTICITY AND THE ROLE OF SUPPRESSOR T CELLS ON HOST RESPONSES (1980) (0)
- Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy between Phorbol Esters and Calcium Ionophores (1986) (0)
- Activation of Guinea Pig B Lymphocytes by Fragments of the Third Component of Complement (1976) (0)
- Regulation of Granulocyte-Macrophage Colony-Stimulating Factor in Murine Lymphocytes (1989) (0)
- Contents, Vol. 34, 1968 (1968) (0)
- RESULTS Generation of Chemotactic Activity for Rabbit PMN in Guinea Pig Peritoneal Exudates (2003) (0)
- The in vitro effect of lymphotoxin on tissue culture fibroblasts. (1972) (0)
- Regulation of fibroblast function by lymphokines and manokines. (1980) (0)
- BIOLOGICAL A C T I V I T Y OF C O M P L E M E N T IN VIVO ROLE OF C5 IN THE ACCUMULATION OF POLYMORPHONUCLEAR LEUKOCYTES IN INFLAMMATORY EXUDATES (2003) (0)
- Purification of Splenic T and B Lymphocytes (2003) (0)
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