Sandro Ghisla

Q: What Schools Are Affiliated With Sandro Ghisla

Sandro Ghisla is affiliated with the following schools: Harvard University, Martin Luther University of Halle-Wittenberg, University of Konstanz

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Sandro Ghisla

Philosophy

#9707

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#13305

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Ontology

#131

World Rank

#145

Historical Rank

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Philosophy

Sandro Ghisla's Degrees

PhD Plant Biology University of Zurich
Masters Plant Sciences University of Zurich

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Sandro Ghisla's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Path from β-Carotene to Carlactone, a Strigolactone-Like Plant Hormone (2012) (676)
Mechanisms of flavoprotein-catalyzed reactions. (1989) (491)
Fluorescence and optical characteristics of reduced flavines and flavoproteins. (1974) (289)
Acyl-CoA dehydrogenases. A mechanistic overview. (2004) (264)
The structure of L‐amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site (2000) (241)
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. (2000) (175)
New flavins for old: artificial flavins as active site probes of flavoproteins. (1986) (168)
ROLE OF CHARGE‐TRANSFER INTERACTIONS IN FLAVOPROTEIN CATALYSIS (1974) (138)
Yeast D-amino acid oxidase: structural basis of its catalytic properties. (2002) (105)
Oxygen Access to the Active Site of Cholesterol Oxidase through a Narrow Channel Is Gated by an Arg-Glu Pair* (2001) (102)
Mechanistic studies with general acyl-CoA dehydrogenase and butyryl-CoA dehydrogenase: evidence for the transfer of the beta-hydrogen to the flavin N(5)-position as a hydride. (1984) (98)
Mechanisms of cell death induction by L-amino acid oxidase, a major component of ophidian venom (2006) (92)
Cholesterol oxidase: biochemistry and structural features (2009) (87)
Studies on succinate dehydrogenase. 8 -Histidyl-FAD as the active center of succinate dehydrogenase. (1972) (84)
Effects of Two Mutations Detected in Medium Chain Acyl-CoA Dehydrogenase (MCAD)-deficient Patients on Folding, Oligomer Assembly, and Stability of MCAD Enzyme (*) (1995) (83)
Kinetic mechanism of D-amino acid oxidases from Rhodotorula gracilis and Trigonopsis variabilis. (1993) (82)
Molecular cloning, expression and purification of L-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma. (2001) (81)
NMR.-Study of nitrogen inversion and conformation of 1,5-dihydro-isoalloxazines ("reduced flavin"). Studies in the flavin series, XIX. (1973) (78)
Plant Carotene Cis-Trans Isomerase CRTISO (2011) (77)
Studies on succinate dehydrogenase. Site of attachment of the covalently-bound flavin to the peptide chain. (1972) (72)
Co-overexpression of bacterial GroESL chaperonins partly overcomes non-productive folding and tetramer assembly of E. coli-expressed human medium-chain acyl-CoA dehydrogenase (MCAD) carrying the prevalent disease-causing K304E mutation. (1993) (71)
Biosynthesis of tetrahydrobiopterin. Purification and characterization of 6-pyruvoyl-tetrahydropterin synthase from human liver. (1986) (70)
On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase (2012) (69)
Characterization of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum. (1997) (69)
Two Similar Gene Clusters Coding for Enzymes of a New Type of Aerobic 2-Aminobenzoate (Anthranilate) Metabolism in the BacteriumAzoarcus evansii (2001) (68)
Identification and properties of new flavins in electron-transferring flavoprotein from Peptostreptococcus elsdenii and pig-liver glycolate oxidase. (1974) (67)
Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans. (2002) (67)
Inactivation of general acyl-CoA dehydrogenase from pig kidney by a metabolite of hypoglycin A. (1981) (66)
7-Substituted pterins: formation during phenylalanine hydroxylation in the absence of dehydratase. (1990) (66)
On the structure of flavin-oxygen intermediates involved in enzymatic reactions. (1977) (66)
Structure and characterization of the glycan moiety of L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. (2001) (66)
Purification and properties of prostaglandin 9-ketoreductase from pig and human kidney. Identity with human carbonyl reductase. (1992) (65)
Fluorescence and optical characteristics of reduced flavins and flavoproteins. (1980) (64)
pH and kinetic isotope effects in d-amino acid oxidase catalysis. (2001) (63)
A mechanistic overview (2004) (63)
Characterization and postulated structure of the primary emitter in the bacterial luciferase reaction. (1984) (62)
8-Mercaptoflavins as active site probes of flavoenzymes. (1979) (62)
Phenylalanine hydroxylase-stimulating protein/pterin-4 alpha-carbinolamine dehydratase from rat and human liver. Purification, characterization, and complete amino acid sequence. (1993) (61)
Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair. (2005) (57)
Characterization of wild-type and an active site mutant of human medium chain acyl-CoA dehydrogenase after expression in Escherichia coli. (1990) (57)
Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity. (1996) (57)
Cholesterol Oxidase from Brevibacterium sterolicum (2001) (57)
A hydrophobic sequence motif common to N-hydroxylating enzymes. (1998) (57)
Mechanism of bacterial bioluminescence: 4a,5-dihydroflavin analogs as models for luciferase hydroperoxide intermediates and the effect of substituents at the 8-position of flavin on luciferase kinetics. (1993) (56)
Metabolic consequences of methylenecyclopropylglycine poisoning in rats. (1991) (56)
Oxidation-reduction of general acyl-CoA dehydrogenase by the butyryl-CoA/crotonyl-CoA couple. A new investigation of the rapid reaction kinetics. (1988) (55)
Properties of flavins where the 8-methyl group is replaced by mercapto- residues. (1979) (54)
Studies on the reaction mechanism of general acyl-CoA dehydrogenase. Determination of selective isotope effects in the dehydrogenation of butyryl-CoA. (1986) (51)
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum. (1999) (51)
Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS‐activator peroxynitrite (2008) (50)
Identification and properties of 8-hydroxyflavin--adenine dinucleotide in electron-transferring flavoprotein from Peptostreptococcus elsdenii. (1976) (50)
Purification of the yellow fluorescent protein from Vibrio fischeri and identity of the flavin chromophore. (1987) (48)
Mechanism of elementary catalytic steps of pyruvate oxidase from Lactobacillus plantarum. (2000) (48)
On the Oxygen Reactivity of Flavoprotein Oxidases (2008) (48)
Mechanism of activation of acyl-CoA substrates by medium chain acyl-CoA dehydrogenase: interaction of the thioester carbonyl with the flavin adenine dinucleotide ribityl side chain. (1999) (48)
The Lycopene Cyclase CrtY from Pantoea ananatis (Formerly Erwinia uredovora) Catalyzes an FADred-dependent Non-redox Reaction* (2010) (47)
L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Comparative sequence analysis and characterization of active and inactive forms of the enzyme. (2001) (47)
Reduced Flavin: NMR investigation of N(5)-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst (2005) (47)
A time-dependent bacterial bioluminescence emission spectrum in an in vitro single turnover system: energy transfer alone cannot account for the yellow emission of Vibrio fischeri Y-1. (1990) (45)
Fluorescence properties of reduced flavins and flavoproteins. (1979) (45)
Structure of the oxygen adduct intermediate in the bacterial luciferase reaction: C nuclear magnetic resonance determination. (1978) (45)
Induction of apoptosis in yeast by L‐amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma (2008) (44)
On The Mechanism of D-Amino Acid Oxidase (1997) (44)
O2 Reactivity of Flavoproteins (2010) (44)
Activation of thiamin diphosphate in enzymes. (1998) (42)
Characterization of D-amino acid oxidase from Trigonopsis variabilis. (1993) (40)
Kinetic studies on the inactivation of L-lactate oxidase by [the acetylenic suicide substrate] 2-hydroxy-3-butynoate. (1976) (40)
Tetrahydrobiopterin biosynthesis. Studies with specifically labeled (2H)NAD(P)H and 2H2O and of the enzymes involved. (1985) (40)
The structure of the covalent flavin adduct formed between lactate oxidase and the suicide substrate 2-hydroxy-3-butynoate. (1976) (39)
Studies on the catalytic mechanism of lactate oxidase. Formation of enantiomeric flavin-N(5)-glycollyl adducts via carbanion intermediates. (1980) (39)
Structure of Phytoene Desaturase Provides Insights into Herbicide Binding and Reaction Mechanisms Involved in Carotene Desaturation. (2017) (38)
Mechanism of inactivation of the flavoenzyme lactate oxidase by oxalate. (1975) (38)
Insights into the formation of carlactone from in‐depth analysis of the CCD8‐catalyzed reactions (2017) (38)
Evaluating the microbicidal, antiparasitic and antitumor effects of CR-LAAO from Calloselasma rhodostoma venom. (2015) (36)
7-substituted pterins in humans with suspected pterin-4a-carbinolamine dehydratase deficiency. Mechanism of formation via non-enzymatic transformation from 6-substituted pterins. (1992) (35)
On the reaction mechanism of L-lactate oxidase: quantitative structure-activity analysis of the reaction with para-substituted L-mandelates. (1997) (35)
Mechanism of hypoglycaemic action of methylenecyclopropylglycine. (1989) (34)
Studies on the reaction mechanism of lactate oxidase. Formation of two covalent flavin-substrate adducts on reaction with glycollate. (1980) (34)
2-Aminobenzoyl-CoA monooxygenase/reductase, a novel type of flavoenzyme. Studies on the stoichiometry and the course of the reaction. (1989) (33)
Medium-long-chain chimeric human Acyl-CoA dehydrogenase: medium-chain enzyme with the active center base arrangement of long-chain Acyl-CoA dehydrogenase. (1996) (33)
Optimization of d‐amino acid oxidase for low substrate concentrations – towards a cancer enzyme therapy (2009) (33)
Beta-oxidation of fatty acids. A century of discovery. (2004) (33)
Biosynthesis of tetrahydrobiopterin: possible involvement of tetrahydropterin intermediates (1984) (32)
Chemical synthesis and some properties of 6-substituted flavins. (1980) (32)
Covalent adducts of lactate oxidase. Photochemical formation and structure identification. (1979) (31)
Spectral detection of an intermediate preceding the excited state in the bacterial luciferase reaction. (1993) (31)
Studies on the mechanism of action of the flavoenzyme lactate oxidase. Proton uptake and release during the binding of transition state analogs. (1977) (31)
Synthesis of the flavocoenzyme of monoamine oxidase (1971) (30)
Isolation and characterization of the transient, luciferase-bound flavin-4a-hydroxide in the bacterial luciferase reaction (1987) (30)
Stereochemistry and accessibility of prosthetic groups in flavoproteins. (1988) (29)
Medium-chain acyl coenzyme A dehydrogenase from pig kidney has intrinsic enoyl coenzyme A hydratase activity. (1986) (29)
Molecular characterization of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: identification of a lys329 to glu mutation in the MCAD gene, and expression of inactive mutant enzyme protein in E. coli (1991) (28)
Substrate activation by acyl-CoA dehydrogenases: transition-state stabilization and pKs of involved functional groups. (1998) (28)
Structural and kinetic analyses of the H121A mutant of cholesterol oxidase. (2006) (27)
NIH shift in flavin-dependent monooxygenation: mechanistic studies with 2-aminobenzoyl-CoA monooxygenase/reductase. (1999) (27)
2-Aminobenzoyl-CoA monooxygenase/reductase, a novel type of flavoenzyme. Identification of the reaction products. (1990) (27)
Plant-type phytoene desaturase: Functional evaluation of structural implications (2017) (26)
Bioluminescence emission from the reaction of luciferase-flavin mononucleotide radical with O2-.. (1983) (26)
Phytoene Desaturase from Oryza sativa: Oligomeric Assembly, Membrane Association and Preliminary 3D-Analysis (2015) (25)
Flavin-dependent alcohol oxidase from yeast. Studies on the catalytic mechanism and inactivation during turnover. (1986) (25)
The crystal and molecular structure of two models of catalytic flavo(co)enzyme intermediates (1978) (23)
Structure of the flavin adduct formed in the suicide reaction of alpha-hydroxybutynoate with D-lactate dehydrogenase. (1979) (23)
CR-LAAO antileukemic effect against Bcr-Abl(+) cells is mediated by apoptosis and hydrogen peroxide. (2016) (22)
Identification and structure of a novel flavin prosthetic group associated with reduced nicotinamide adenine dinucleotide dehydrogenase from Peptostreptococcus elsdenii. (1973) (22)
The synthesis of succinate-dehydrogenase riboflavin. (1970) (22)
Location of the active site and proposed catalytic mechanism of pterin-4a-carbinolamine dehydratase. (1996) (21)
Structure and catalytic inactivity of the bacterial luciferase neutral flavin radical. (1982) (21)
Biochemical characterization of purified, human recombinant Lys304-->Glu medium-chain acyl-CoA dehydrogenase containing the common disease-causing mutation and comparison with the normal enzyme. (1997) (21)
FAD analogues as prosthetic groups of human glutathione reductase. Properties of the modified enzyme species and comparisons with the active site structure. (1985) (20)
Protonic equilibria in the reductive half-reaction of the medium-chain acyl-CoA dehydrogenase. (1998) (20)
Thermal unfolding of medium-chain acyl-CoA dehydrogenase and iso(3)valeryl-CoA dehydrogenase: study of the effect of genetic defects on enzyme stability. (2004) (20)
Biosynthesis of riboflavin. 6,7-Dimethyl-8-ribityllumazine 5'-phosphate is not a substrate for riboflavin synthase. (1978) (20)
Studies with Lysine N6-Hydroxylase. Effect of a Mutation in the Assumed FAD Binding Site on Coenzyme Affinities and on Lysine Hydroxylating Activity (1999) (20)
Human pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor-1 alpha. Characterization and kinetic analysis of wild-type and mutant enzymes. (1995) (20)
The Mechanism of Action of Flavoprotein - Catalyzed Reactions (1983) (19)
Time‐Resolved Fluorescence Study of the Dissociation of FMN from the Yellow Fluorescence Protein from Vibrio fischeri (1997) (19)
Suicide inactivation of the flavoenzyme D-lactate dehydrogenase by alpha-hydroxybutynoate. (1979) (18)
Studies on glycollate oxidase from pea leaves determination of stereospecificity and mode of inhibition by α-hydroxybutynoate (1982) (18)
2-Aminobenzoyl-CoA monooxygenase/reductase. Evidence for two distinct loci catalyzing substrate monooxygenation and hydrogenation. (1995) (17)
Biochemical characterization of a variant human medium-chain acyl-CoA dehydrogenase with a disease-associated mutation localized in the active site. (1999) (17)
Characterization of human and pig kidney long-chain-acyl-CoA dehydrogenases and their role in beta-oxidation. (1997) (17)
8-Azidoflavins as photoaffinity labels for flavoproteins. (1985) (16)
On the reaction of d‐amino acid oxidase with dioxygen: O2 diffusion pathways and enhancement of reactivity (2011) (16)
Flavoenzyme structure and function. Approaches using flavin analogues. (1999) (16)
Redox properties of human medium-chain acyl-CoA dehydrogenase, modulation by charged active-site amino acid residues. (1998) (16)
4-Thioflavins as active site probes of flavoproteins. General properties. (1984) (15)
L-Lactate oxidase (1991) (15)
Purification of 6-pyruvoyl-tetrahydropterin synthase from human liver. (1986) (14)
Oxidation of 2-thioflavins by peroxides. Formation of flavin 2-S-oxides. (1983) (13)
Structure of a novel flavin chromophore from Avena coleoptiles, the possible 'blue light' photoreceptor. (1984) (13)
Molecular evolution and substrate specificity of acyl-CoA dehydrogenases: chimaeric "medium/long' chain-specific enzyme from medium-chain acyl-CoA dehydrogenase. (1996) (12)
l-Amino acid oxidase isolated from Calloselasma rhodostoma snake venom induces cytotoxicity and apoptosis in JAK2V617F-positive cell lines (2016) (12)
Catalytic and redox properties of glycine oxidase from Bacillus subtilis. (2009) (12)
Studies with general acyl-CoA dehydrogenase from pig kidney. Inactivation by a novel type of "suicide" inhibitor, 3,4-pentadienoyl-CoA. (2008) (12)
Studies on the active centre of Rhodotorula gracilis D-amino acid oxidase and comparison with pig kidney enzyme. (1992) (12)
New aspects in biopterin biosynthesis in man (1981) (11)
Preparation and some properties of 6-substituted flavins as active site probes for flavin enzymes. (1986) (11)
Absorption and emission spectroscopic characterisation of 8-amino-riboflavin (2009) (10)
6-Thiocyanatoflavins and 6-mercaptoflavins as active-site probes of flavoproteins. (1986) (10)
Characterization of wild-type human medium-chain acyl-CoA dehydrogenase (MCAD) and mutant enzymes present in MCAD-deficient patients by two-dimensional gel electrophoresis: evidence for post-translational modification of the enzyme. (1994) (10)
[35] Isolation, synthesis, and properties of 8-hydroxyflavins (1980) (10)
Formation of 3‐hydroxyglutaric acid in glutaric aciduria type I: in vitro participation of medium chain acyl‐CoA dehydrogenase (2019) (10)
BORONIC ACIDS AS MECHANISTIC PROBES FOR THE BACTERIAL LUCIFERASE REACTION (1991) (10)
Electronic effects of 7 and 8 ring substituents as predictors of flavin oxidation-reduction potentials (1999) (10)
Biosynthesis of tetrahydrobiopterin in man (1985) (9)
Dehydrogenation Mechanism in Flavoprotein Catalysis (1982) (9)
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335. (2004) (9)
Model Studies on Flavin-Dependent Carbonyl-Activation: Reduction of Carbonyl Compounds by Flavohydroquinone (1972) (9)
Molecular complex of lumiflavin and 2-aminobenzoic acid: crystal structure, crystal spectra, and solution properties. (1981) (9)
6-Azido- and 6-aminoflavins as active-site probes of flavin enzymes. (1986) (9)
[12] Bacterial luciferase intermediates: The neutral flavin semiquinone, its reaction with superoxide, and the flavin 4a-hydroxide (1986) (8)
Studies on the Mechanism of Bacterial Bioluminescence : Evidence Compatible with a One Electron Transfer Process and a CIEEL Mechanism in the Luciferase Reaction (1987) (8)
STRUCTURE/LINEAR FREE ENERGY CORRELATIONS AND DEUTERIUM KINETIC ISOTOPE EFFECTS USING SUBSTITUTED PHENYLGLYCINES* (1997) (7)
1H-NMR and mass spectrometric studies of tetrahydropterins. Evidence for the structure of 6-pyruvoyl tetrahydropterin, an intermediate in the biosynthesis of tetrahydrobiopterin. (1990) (7)
Evidence for a concerted mechanism in substrate dehydrogenation via hydride transfer (2001) (7)
Structural, spectroscopic and catalytic activity studies on glutathione reductase reconstituted with FAD analogues. (1991) (7)
Solvent isotope effects in reactions of human medium-chain acyl-CoA dehydrogenase active site mutants. (2007) (7)
Kinetic and mechanistic studies on the reactions of 2-aminobenzoyl-CoA monooxygenase/reductase. (1995) (7)
Oxidases, dehydrogenases and related systems (2012) (7)
Mechanisms of enzyme inhibition by hypoglycin, methylenecyclopropylglycine and their metabolites. (1990) (7)
Revisitation of the βCl-Elimination Reaction of d-Amino Acid Oxidase (2011) (7)
Very high resolution crystal structure of D-Amino acid oxidase : insights into the reaction mechanisms and mode of ligand binding (1999) (6)
Suicide Substrates as Irreversible Inhibitors of Flavoenzymes (1980) (6)
A century of discovery (2004) (6)
Human Pterin‐4α‐Carbinolamine Dehydratase/Dimerization Cofactor of Hepatocyte Nuclear Factor‐1α (1995) (6)
Ionisation Properties of Reduced, 1,5-Dihydroflavin, Rates of N(5)-H Exchange with Solvent (1991) (6)
4-Thioflavins as active site probes of flavoproteins. Reactions with sulfite. (1984) (5)
Prostaglandin 9-ketoreductase from pig and human kidney: purification, properties and identity with human carbonyl reductase. (1992) (5)
RECENT ADVANCES IN TETRAHYDROBIOPTERIN BIOSYNTHESIS AND THE TREATMENT OF HUMAN DISEASE (1983) (5)
Fluorescence Properties of Luciferase Peroxyflavins Prepared with ISO-FMN and 2-THIO FMN (1981) (5)
Characterization of a disease-causing Lys329 to Glu mutation in 16 patients with medium-chain Acyl-CoA dehydrogenase deficiency (1991) (5)
Immunochemical and molecular analysis of medium-chain acyl CoA dehydrogenase deficiency (1990) (5)
Studies in the flavin series. Part XVI. Alkylation and rearrangement reactions of dihydroalloxazines (1971) (5)
Studies in the flavin series. Part XVII. (1972) (4)
Characterization of Human Pterin-4a-carbinolamine Dehydratase/Dimerization Cofactor of Hepatocyte Nuclear Factor-1α, and of the Cys81-mutant Involved in Hyperphenylalanincemia (1995) (4)
Studies on the active centres of flavoproteins: binding of 8-hydroxy-FAD and 8-hydroxy-FMN to apoproteins (1976) (4)
On the role of the 376-functional group in catalysis by medium chain Acyl-CoA-dehydrogenase (2002) (4)
Bioluminescence emission of bacterial luciferase with 1-deaza-FMN. Evidence for the noninvolvement of N(1)-protonated flavin species as emitters. (1989) (4)
Spectroscopic characterization of human liver pterin 4a-carbinolamine dehydratase. (1993) (4)
A reply to Dick et al. (1998) (4)
On the role of Glu376 in catalysis of acyl-CoA dehydrogenases (1991) (3)
Chemistry and biology of pteridines, 1989 : pteridines and folic acid derivatives : proceedings of the Ninth International Symposium on Pteridines and Folic Acid Derivatives, Chemical, Biological, and Clinical Aspects, Zurich, Switzerland, September 3-8, 1989 (1990) (3)
Tetrahydrobiopterin biosynthesis in man (1986) (3)
Suspected pterin-4a-carbinolamine dehydratase deficiency: Hyperphenylalaninaemia due to inhibition of phenylalanine hydroxylase by tetrahydro-7-biopterin (1992) (3)
Studies on the glycosylation of L-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma (1999) (3)
PHOTOCHEMICAL FORMATION AND STRUCTURE IDENTIFICATION (1979) (3)
Bacterial luciferase : bioluminescence emission using lumanzines as substrates (1994) (3)
Pterin-4a-Carbinolamine Dehydratase from Pseudomonas aeruginosa: Characterization, Catalytic Mechanism and Comparison to the Human Enzyme (1998) (3)
On the chemical mechanisms of bacterial luciferase, an updating (1987) (3)
pH and substrate chain length dependence of the activity of "short-chain"-, "medium-chain"- and "long-chain" -acyl-CoA dehydrogenase (1997) (3)
Chemical Considerations on the Biosynthesis of Tetrahydrobiopterin (1984) (2)
Structurally different rat liver medium-chain acyl CoA dehydrogenases directed by complementary DNAs differing in their 5'-region. (1991) (2)
Flavins and flavoproteins 1999 : proceedings of the Thirteenth International Symposium, Konstanz, Germany, August 29 - September 4, 1999 (1999) (2)
Purification and Characterization of a Carbonyl Reductase from Human Liver, which is Competent in the Reduction of 6-Pyruvoyl-Tetrahydropterin (1989) (2)
Chemistry and molecular biology of flavin in the "fully reduced" state (1971) (2)
Alpha, beta-dehydrogenation by acyl-CoA dehydrogenases: role of functional groups at the active center. (1992) (2)
L-Lactate monooxygenase, proposed active site structure and mechanism (1991) (2)
The Bacterial Luciferase Neutral Flavin Radical : Identification and Catalytic Inactivity (1982) (2)
Aromatic substrate analogues as mechanistic probes for medium-chain acyl-CoA dehydrogenases (1991) (2)
Substrate chain length specificity of acyl-CoA dehydrogenases : studies on different mutants (1999) (2)
Some Properties of Glu-376-Gln Active Site Mutant of Human Medium-Chain Acyl-CoA Dehydrogenase (1991) (2)
Identification of the luciferase-bound flavin-4a-hydroxide as the primary emitter in the bacterial bioluminescence reaction (1984) (2)
In vitro synthesis of pig kidney general acyl CoA dehydrogenase. (1986) (2)
Studies on the bacterial luciferase reaction : Isotope effects on the light emission (1984) (2)
Inactivation of general acyl-CoA dehydrogenase from pig kidney by the suicide substrate methylenecyclopropylacetyl-CoA : structure of one of the covalent flavin-inhibitor adducts (1987) (2)
Oxygen diffusion in D-amino acid oxidase (2010) (1)
Mechanism of alpha, beta-dehydrogenation of Fatty Acid CoA Derivatives by Flavin Enzymes (1984) (1)
Molecular cloning of cDNA for rat liver general acyl CoA dehydrogenase and homology between the rat liver and pig kidney enzymes. (1987) (1)
Purification of 6-pyruvoyl-tetrahydropterin 2'-keto reductase from human liver (1987) (1)
Picosecond Dynamics Fluorescence of reduced flavins (1991) (1)
On the Inactivation of General Acyl-CoA-Dehydrogenase from Pig Kidney by Methylenecyclopropyl-Acetyl-CoA, a Metabolite of Hypoglycin : Studies with flavin modified enzymes (1984) (1)
On the mechanism of bacterial luciferase.4a,5-Dihydroflavins as model compounds for reaction intermediates (1991) (1)
Isolation, synthesis, and properties of 8-hydroxyflavins. (1980) (1)
Three Histidines in Pterin -4a -carbinolamine Dehydratase are the Important Residues for Substrate Binding and Catalysis (1996) (1)
Studies on the elimination reaction of Rhodotorula gracilis D-Amino acid oxidase with beta-chloro-D-alanine (2002) (1)
Biochemical characterization of a mutant human medium-chain acyl-CoA dehydrogenase present in patients having deficient activity (1991) (1)
Single step analysis of catalysis of pyruvate oxidase from Lactobacillus plantarum : kinetics, mechanism and regulation (1999) (1)
New Trends in beta-Oxidation : advances in the study of alpha,beta-Dehydrogenation (1991) (1)
Probing the electron transfer properties of human medium-chain acyl-CoA dehydrogenase and site-directed mutants (1996) (1)
Progress in the study of biosynthesis and role of 7-substituted pterins: function of pterin-4a-carbinolamine dehydratase. (1993) (1)
Two molecules play particular roles in the process: Long chain aldehyde (C myristic aldehyde) and FMN are cosubstrates of the enzyme (1987) (0)
Glutathione Reductase Species Containing FAD Analogues (1984) (0)
ns L-LACTATE MONOOXYGENASE , PROPOSED ACTIVE SITE STRUCTURE AND MECIIANISM (2008) (0)
Studies with the Flavin Dependent Alcohol Oxidase from Yeast : Properties and Catalytic Mechanism (1984) (0)
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase (1999) (0)
FAD analogues as active site probes of Rhodotorula gracilis D-amino acid oxidase (1991) (0)
MEDIUM-CHAIN ACYL-CoA DEHYDROGENASE BY METHYLENECYCLOPROPYL-ACETYL-CoA: A NEW TYPE OF FLAVIN-INHIBITOR ADDUCT (1990) (0)
On the mechanism of pterin-4a-carbinolamine dehydratase : synthesis of new substrate analogues and interaction with the enzyme (1997) (0)
Hydroxylation by flavin enzymes : evidence for NIH-shift mechanism (1999) (0)
2-aminobenzoyl-CoA monooxygenase/reductase, a novel type of flavoprotein hydroxylase (1991) (0)
The acyl-CoA dehydrogenases (2013) (0)
Reprint from Flavins and Flavoproteins (2008) (0)
7-substituted pterins: formation and occurrence. (1992) (0)
Lumazimes as Coenzymes in Flavodoxin : Evidence for the Occurrence of Lumazine Semiquinones (1979) (0)
THE COVALENTLY BOUND FLAVIN ACTIVE CENTER OF SUCCINATE DEHYDROGENASE (1972) (0)
Hydrogen tunnelling in amine dehydrogenases from methylotrophic bacteria (1999) (0)
Activation of thiamin diphosphate in enzymes 1 BIOCHIMICA (2008) (0)
Crystal structure of Phytoene desaturase CRTI from Pantoea ananatis (2012) (0)
Reviewers Acknowledgement (2020) (0)
6-pyruvoyl-tetrahydropterin reductases (1990) (0)
Structure and function of Rhodotorula gracilis D-amino acid oxidase : 2. Site-directed mutagenesis of arginine 285 and pH effects (1999) (0)
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands (1999) (0)
CRYSTAL STRUCTURE OF L-AMINO ACID OXIDASE FROM CALLOSELASMA RHODOSTOMA COMPLEXED WITH CITRATE (2000) (0)
Mutation in an hydrophobic sequence motif common to N-hydroxylating enzymes (1999) (0)
PURIFICATION AND PARTIAL CHARACTERIZATION OF 6-PYRUVOYL TETRAHYDROPTERIN REDUCTASE FROM HUMAN LIVER (1989) (0)
Biosynthesis of tetrahydrobiopterin : Incorporation of label from reduced pyridine nucleotide during formation from dihydroneopterin triphosphate (1985) (0)
2-aminobenzoyl-CoA-monooxygenase/reductase, an enzyme with two distinct functions and one active center (1994) (0)
O 2 Reactivity of Flavoproteins DYNAMICACCESSOFDIOXYGENTOTHEACTIVESITEANDROLEOFAHRELAYSYSTEM IN D-AMINOACIDOXIDASE * (2010) (0)
Comparison of the Toxicity of Hypoglycin from Blighia Sapida and of its Lower Homologue Methylenecyclopropylglycine from Litchi Chinensis (1990) (0)
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus : a covalent FAD binding vs. a non-covalent one (1999) (0)
4-Thioflavins as Active Site Probes of Flavoproteins : Reaction with Sulfite and Formation of 4-Hydroxy-4-sulfonylflavins (1984) (0)
Structural and mechanistic studies with pterin-4a-carbinolamine dehydratase from Pseudomonas aeruginosa : three-dimensional structure and comparison with the human enzyme (1997) (0)
Mechanism of alpha,beta-dehydrogenation by acyl-CoA dehydrogenases (1994) (0)
CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE FROM B.STEROLICUM (2001) (0)
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA (1997) (0)
Cytotoxicity evaluation of l-amino acid oxidase from Calloselasma rhodostoma in breast cancer cells MCF-7 and SK-BR-3 (2014) (0)
BH4-Biosynthesis: 1H-NMR Evidence for the Pyruvoyl-tetrahydropterin-synthase Catalyzed Formation of 6-Pyruvoyl-tetrahydropterin from Dihydroneopterin Triphosphate (1986) (0)
Studics on the Glycosylatiou of L-amiuo Acid Oxidase Frolll the Malayau Pit Viper Calloselasma Rlzodostoma (2008) (0)
The Red Absorbing Flavin Species in the Reaction of Bacterial Luciferase with FMNH2 and O2 (1981) (0)
Characterization of medium-chain acyl-CoA dehydrogenase (MCAD) with a point mutation associated with MCAD deficiency. (1992) (0)
New Trends in j 3-0 xidation : Advances In the Study of a , j 3-Dehydrogenation • (0)
1H-NMR studies with tetrahydrobiopterins, evidence for the structure of 6-pyruvoyltetrahydropterin, an intermediate in the biosynthesis of tetrahydrobiopterin (1987) (0)
D-AMINO ACID OXIDASE: STRUCTURE OF SUBSTRATE COMPLEXES AT VERY HIGH RESOLUTION REVEAL THE CHEMICAL REACTTION MECHANISM OF FLAVIN DEHYDROGENATION (2000) (0)
PROPOSED ACTIVE SITE STRUCTURE AND MECHANISM (1990) (0)
Isolation and characterization of the transient , luciferase-bound flavin-4 a-hydroxide in the bacterialluciferase reaction (2008) (0)
Bacterial luciferase: Bioluminescence emission using lumazines as analogs of FMN (1993) (0)
SYNTH. DES SUCCINAT‐DEHYDROGENASE‐RIBOFLAVINS (1970) (0)
Inactivation of medium-chain acyl-CoA dehydrogenase from pig kidney by methylenecyclopropyl-acetyl-CoA : identification of a new flavin-inhibitor adduct (1991) (0)
TETRAHYDROBIOPTERIN BIOSYNTHESIS. STUDIES ON THE REACTION OF DIHYDRONEOPTERIN TRIPHOSPHATE IN THE PRESENCE OF PHOSPHATE-ELIMINATING ENZYME FROM HUMAN LIVER (1985) (0)
CRYSTAL STRUCTURE OF D-AMINO ACID OXIDASE IN COMPLEX WITH TWO ANTHRANYLATE MOLECULES (2002) (0)
Studies on the active site of human erythrocyte glutathione reductase using 6-SCN-FAD and 6-Mercapto-FAD (1987) (0)
Reaction of General Acyl-CoA Dehydrogenase with 3,4-Pentadienoyl-CoA (1982) (0)
Phosphate mediates electron transfer in pyruvate oxidase from Lactobacillus plantarum (2002) (0)
Medium chain Acyl-CoA dehydrogenase genetic defects : identification and partial characterisation of two new patient mutants (1999) (0)
l-amino acid oxidase from Calloselasma rhodostoma potentiates tyrosine kinase inhibitors effect in Bcr-Abl positive cells (2014) (0)
The Crystal and Molecular Structure of Two Models of Catalytic Flavo(eo)enzyme Intermediates (2001) (0)
Purification and partial characterization of human isobutyryl-CoA dehydrogenase : a novel member of the Acyl-CoA dehydrogenases family (2002) (0)
CRYSTAL STRUCTURE OF L-AMINO ACID OXIDASE FROM CALLOSELASMA RHODOSTOMA, COMPLEXED WITH THREE MOLECULES OF O-AMINOBENZOATE. (2000) (0)
Induction of cell death by L-amino acid oxidase, a main component of snake venom (2004) (0)
Studies with Old Yellow Enzyme, Reconstruction with Lumazine Analogs as Coenzyme (1983) (0)
Oligomerization and aggregation of lysine N6-hydroxylase : an enzyme of the bacterial aerobactin biosynthesis (1999) (0)
CRYSTAL STRUCTURE ANALYSIS OF D-AMINO ACID OXIDASE IN COMPLEX WITH L-LACTATE (2000) (0)
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE (1997) (0)
Biosynthesis of Flavoproteins (1987) (0)
D-AMINO ACIC OXIDASE IN COMPLEX WITH D-ALANINE AND A PARTIALLY OCCUPIED BIATOMIC SPECIES (2000) (0)
Purification and some properties of five distinct acyl-CoA dehydrogenases from bovine liver (1991) (0)
Structure and Function of Rhodo{orttla Gracilis D-amil1o Acid Oxidase 2. Site-directed Mutagenesis of Arginine 285 and Pb Effects (2008) (0)
MECHANISM OF oc,B-DEHYDROGENATION OF FATTY ACID CoA DERIVATIVES (2008) (0)
Studies in the flavin series. XVII. (1972) (0)
Comparison of the amino acid sequence or Calloselasma rhodostoma L-amino acid oxidase to other FAD-dependent oxidases (1999) (0)

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