Santiago Grisolı́a

Santiago Grisolı́a's AcademicInfluence.com Rankings

Santiago Grisolı́a

Biology

#6068

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#8701

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Neuroscience

#715

World Rank

#747

Historical Rank

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Biology

Santiago Grisolı́a's Degrees

PhD Neuroscience University of Buenos Aires
Masters Biology University of Buenos Aires
Bachelors Biology University of Buenos Aires

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Santiago Grisolı́a's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors (1992) (188)
Brain ATP Depletion Induced by Acute Ammonia Intoxication in Rats Is Mediated by Activation of the NMDA Receptor and Na+, K+‐ATPase (1994) (185)
A sensitive and convenient micromethod for estimation of urea, citrulline, and carbamyl derivatives. (1966) (156)
The urea cycle (1976) (145)
Catalytic rôle of of glutamate derivatives in citrulline biosynthesis. (1953) (143)
THE CATALYTIC ENVIRONMENT AND ITS BIOLOGICAL IMPLICATIONS. (1964) (106)
Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures (1993) (102)
NMDA Receptor antagonists prevent acute ammonia toxicity in mice (1996) (102)
The purification and properties of hydropyrimidine hydrase. (1957) (99)
Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemia. (1970) (97)
Thermogenic and adaptive mechanisms in hibernation and arousal from hibernation. (1960) (96)
Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons (1998) (95)
The microestimation, distribution, and biosynthesis of 2, 3-diphosphoglyceric acid. (1957) (92)
Age-dependent decrease of carnitine content in muscle of mice and humans. (1989) (92)
Glutamate Induces a Calcineurin‐Mediated Dephosphorylation of Na+,K+‐ATPase that Results in Its Activation in Cerebellar Neurons in Culture (1996) (90)
The catalytic rôle of carbamyl glutamate in citrulline biosynthesis. (1952) (84)
Long-term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamoyl-phosphate synthase. (1988) (83)
Changes in glutathione in acute and chronic alcohol intoxication (1980) (83)
Ammonia Prevents Activation of NMDA Receptors by Glutamate in Rat Cerebellar Neuronal Cultures (1995) (74)
Turnover of carbamyl-phosphate synthase, of other mitochondrial enzymes and of rat tissues. Effect of diet and of thyroidectomy. (1977) (74)
Purification and properties of a nonspecific acid phosphatase from wheat germ. (1960) (70)
Ammonium Injection Induces an N‐Methyl‐d‐Aspartate Receptor‐Mediated Proteolysis of the Microtubule‐Associated Protein MAP‐2 (1993) (68)
Influence of prolonged ethanol intake on the levels and turnover of alcohol and aldehyde dehydrogenases and glutathione. (1980) (68)
Use of rhodamine 123 to investigate alterations in mitochondrial activity in isolated mouse liver mitochondria. (1988) (66)
Synthesis of citrulline with animal and bacterial enzymes. (1960) (66)
Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism (1995) (64)
Carnitine and choline derivatives containing a trimethylamine group prevent ammonia toxicity in mice and glutamate toxicity in primary cultures of neurons. (1996) (61)
Phosphoglycerate mutase from yeast, chicken breast muscle, and kidney (2, 3-PGA-dependent). (1975) (59)
Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase. (1968) (56)
The kinetic properties of yeast and muscle phosphoglyceric acid mutase. (1957) (55)
Regulation of lysosomal autophagy in transformed and non-transformed mouse fibroblasts under several growth conditions. (1984) (55)
Chronic ethanol treatment affects synaptosomal membrane-bound enzymers (1983) (54)
Distribution of two types of phosphoglyceric acid mutase, diphosphoglycerate mutase, and D-2,3-diphosphoglyceric acid. (1959) (54)
Glutamate dehydrogenase from yeast and from animal tissues (1964) (53)
Lack of correlation between glutamate-induced depletion of ATP and neuronal death in primary cultures of cerebellum (1995) (53)
Chronic hyperammonemia prevents changes in brain energy and ammonia metabolites induced by acute ammonium intoxication. (1993) (53)
The influence of prolonged ethanol intake on the levels and turnover of alcohol and aldehyde dehydrogenases and of brain (Na + K)-ATPase of rats. (1978) (51)
Inhibition of protein kinase C induces differentiation in Neuro-2a cells. (1990) (49)
Inhibition of Protein Kinase C Restores Na+, K+‐ATPase Activity in Sciatic Nerve of Diabetic Mice (1992) (47)
Carbamoyl phosphate synthetase I of human liver. Purification, some properties and immunological cross-reactivity with the rat liver enzyme. (1981) (47)
Mitochondrial carbamoyl phosphate synthetase activity in the absence of N-acetyl-L-glutamate. Mechanism of activation by this cofactor. (1983) (47)
A specific inhibitor of protein kinase C induces differentiation of neuroblastoma cells. (1990) (47)
Effects of L-carnitine on urea synthesis following acute ammonia intoxication in mice. (1984) (45)
Automatic procedure for the microestimation of 2,3-diphosphoglycerate. (1969) (45)
Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. (1997) (43)
Mechanism of action of 2,3-diphosphoglycerate-independent phosphoglycerate mutase. (1971) (43)
Significance of the rapid degradation of newly synthesized proteins in mammalian cells: a working hypothesis. (1982) (42)
The potentiation of ammonia toxicity by sodium benzoate is prevented by L-carnitine. (1987) (42)
Mechanism of carbamoyl-phosphate synthetase. Properties of the two binding sites for ATP. (1979) (41)
The purification and properties of hydropyrimidine dehydrogenase. (1957) (41)
Studies on glycerate 2,3-diphosphatase. (1958) (39)
Crystalline phosphoglyceric acid mutase. (1956) (38)
Inhibition of protein kinase C induces differentiation of neuroblastoma cells (1989) (37)
Vanadate inhibits 2,3-bisphosphoglycerate dependent phosphoglycerate mutases but does not affect the 2,3-bisphosphoglycerate independent phosphoglycerate mutases. (1980) (37)
Mechanism of mitochondrial carbamoyl-phosphate synthetase: synthesis and properties of active CO2, precursor of carbamoyl phosphate. (1977) (36)
Rats fed prolonged high protein diets show an increase in nitrogen metabolism and liver megamitochondria. (1987) (36)
Modulation of Glutamine Synthesis in Cultured Astrocytes by Nitric Oxide (1997) (35)
Enzymatic decarbamylation of carbamyl beta-alanine and carbamyl beta-aminoisobutyric acid. (1958) (35)
Effect of streptozotocin diabetes on some urea cycle enzymes. (1982) (35)
Molecular mechanism of acute ammonia toxicity and of its prevention by L-carnitine. (1994) (35)
Binding of 2,3-diphosphoglycerate to oxyhemoglobin. (1969) (35)
Hyperammonemia decreases protein-kinase-C-dependent phosphorylation of microtubule-associated protein 2 and increases its binding to tubulin. (1993) (35)
Deacylation and transacetylation of acetyl glutamate and acetyl ornithine in rat liver (1977) (34)
Purification and properties of brain carbamyl and acyl phosphatase. (1958) (34)
Ornithine transcarbamylase activity in serum. (1959) (33)
Ramón y Cajal's contribution to the neurosciences : proceedings of the Symposium "Horizons in Neuroscience", honoring the 100th anniversary of Santiago Ramón y Cajal's research career, 25-27 March, 1982, Valencia, Spain (1983) (33)
Growth, enzymes and hormonal changes in offspring of alcohol-fed rats. (1984) (33)
Immunohistochemical localization of glutamate dehydrogenase in rat liver: plasticity of distribution during development and with hormone treatment. (1988) (33)
The molecular properties of yeast and muscle phosphoglyceric acid mutase. (1957) (33)
THE RÔLE OF CARBAMYL-l-GLUTAMIC ACID IN THE ENZYMATIC SYNTHESIS OF CITRULLINE FROM ORNITHINE (1950) (33)
Study of citrulline synthesis with soluble enzyme preparations. (1951) (32)
A highly active carbamate kinase and its application to the regeneration and preparation of [32P] adenine nucleotides. (1960) (32)
Activation of the metabotropic glutamate receptor mGluR5 prevents glutamate toxicity in primary cultures of cerebellar neurons. (1997) (31)
Lesch‐Nyhan Syndrome, Caffeine Model: Increase of Purine and Pyrimidine Enzymes in Rat Brain (1984) (31)
Mechanism of carbamoyl-phosphate synthetase. Binding of ATP by the rat-liver mitochondrial enzyme. (1979) (30)
Electron microscopic localization of glutamate dehydrogenase in rat liver mitochondria by an immunogold procedure and monoclonal and polyclonal antibodies. (1986) (30)
The purification and properties of muscle diphosphoglycerate mutase. (1959) (30)
Effects of acute hyperammonemiain Vivo on oxidative metabolism in nonsynaptic rat brain mitochondria (1997) (30)
Biochemical regulatory mechanisms in eukaryotic cells (1972) (29)
HYPOXIA, SAFFRON, AND CARDIOVASCULAR DISEASE (1974) (29)
L-Carnitine increases the affinity of glutamate for quisqualate receptors and prevents glutamate neurotoxicity (1994) (28)
Mechanism of activation of bicarbonate ion by mitochondrial carbamoyl-phosphate synthetase: formation of enzyme-bound adenosine diphosphate from the adenosine triphosphate that yields inorganic phosphate. (1981) (28)
Effects of lithium, and lithium and alcohol administration on (Na + K)-ATPase. (1981) (27)
Metabolic regulation and enzyme action (1970) (27)
Regulation of mitochondrial protein concentration: a plausible model which may permit assessing protein turnover. (1985) (27)
Protective effect of long term ammonium ingestion against acute ammonium intoxication. (1988) (27)
On Specific Dynamic Action, Turnover, and Protein Synthesis (2015) (26)
Mechanism of yeast phosphoglycerate mutase. (1972) (26)
Vanadate increases oxygen affinity and affects enzyme activities and membrane properties of erythrocytes. (1981) (26)
The effects of mercury and other reagents on phosphoglycerate mutase-2,3-diphosphoglycerate phosphatase from kidney, muscle and other tissues. (1970) (25)
Biosynthesis and Utilization of Acetyl Phosphate, Formyl Phosphate, and Carbamyl Phosphate and their Relations to the Urea Cycle (1964) (25)
Decrease in thermal stability of frog liver carbamyl phosphate synthetase by substrates and cofactors (1959) (25)
The intermediate role of carbamyl-L-glutamic acid in citrulline synthesis. (1948) (25)
Carbamoylation of proteins following administration to rats of carbamoyl phosphate and cyanate and effects on memory. (1973) (25)
Prenatal Exposure of Rats to Ammonia Impairs NMDA Receptor Function and Affords Delayed Protection Against Ammonia Toxicity and Glutamate Neurotoxicity (1995) (25)
Insulin degradation by lysosomal extracts from rat liver; model for a role of lysosomes in hormon degradation. (1976) (24)
[26] Phosphoglyceric Acid Mutase: 2,3-DPGA + 3-PGA ⇄ 2,3-DPGA + 2-PGA (crystalline) (1); 3-PGA ⇄ 2-PGA (2) (1962) (24)
Glutamate and muscarinic receptors in the molecular mechanisms of acute ammonia toxicity and of its prevention. (1997) (24)
Enzyme regulation by substrate; rapid inactivation of glutamate dehydrogenase by carbamyl phosphate. (1968) (24)
Control of urea synthesis and ammonia utilization in protein deprivation and refeeding. (1991) (24)
Changes in the levels of urea cycle enzymes and in metabolites thereof in diabetes. (1981) (24)
Enzymic interconversion of hydrouracil and β-ureidopropionic acid (1955) (24)
On the mechanism of carbamoylphosphate synthetase. (1972) (24)
Human carbamoylphosphate synthetase I. (1981) (23)
Immunoferritin location of carbamoyl phosphate synthetase in rat liver. (1979) (23)
Effect of L-carnitine on ketone bodies, redox state and free amino acids in the liver of hyperammonemic mice. (1987) (23)
Variations in malic dehydrogenase activity, with lyophilization, dialysis, and conditions of incubation. (1961) (23)
Prevention of ammonia toxicity byl-carnitine: metabolic changes in brain (1984) (22)
Influence of the route of administration on the protective effect of L-carnitine on acute hyperammonemia. (1986) (22)
Prominent role of lysosomes in the proteolysis of rat liver mitochondria at neutral pH (1977) (21)
Treating urea cycle defects (1981) (20)
Effect of cofactors, oestrogens and magnesium ions on the activity and stability of human glutamate dehydrogenase. (1964) (20)
Acylation of lysine and of arginine-rich histones with carbamyl phosphate and 1,3 diphosphoglycerate. (1970) (20)
Inhibition of protein kinase C arrests proliferation of human tumors (1991) (20)
Biosynthesis of carbamyl aspartate in pigeon and rat tissues. (1962) (20)
Fate of proteins synthesized in mitochondria of cultured mammalian cells revealed by electron microscope radioautography. (1980) (20)
Glutamate-dehydrogenase inactivation by reduced nicotinamide-adenine dinucleotide phosphate. (1962) (19)
The purification and properties of phosphoglycerate mutase from chicken breast muscle. (1966) (19)
Effects of prenatal and postnatal exposure of rats to alcohol: Changes in (Na+K+) ATPase (1982) (19)
New aspects of acetylglutamate action. Cold inactivation of frog carbamyl phosphate synthetase. (1961) (19)
Some comparative aspects of carbamylation of human blood and of hemoglobin with cyanate and carbamyl phosphate. (1972) (19)
Homogenous crystalline phosphoglycerate phosphomutase of high activity. A simple method for lysis of yeast. (1968) (19)
Autophagy of mitochondria in rat liver assessed by immunogold procedures. (1988) (18)
Effect of hyperammonemia on the levels of carnitine in mice (1987) (18)
Variations in heat stability of enzymes with substrates and cofactors (1959) (18)
Properties of pure acyl phosphatase from bovine brain. (1969) (18)
Metabolic functions of biotin; the synthesis of citrulline from ornithine in liver tissue from normal and biotin-deficient rats. (1949) (18)
Inactivation of Enzymes by Aspirin and Salicylate (1968) (18)
Caffeine Ingestion by Rats Increases Noradrenaline Turnover and Results in Self‐Biting (1986) (18)
Influence of ionic strength on apparent reaction mechanism of phosphoglycerate mutase. (1966) (18)
Phosphoglyceric acid mutase activity without added 2,3-diphosphoglycerate in preparations purified from rice germ. (1960) (18)
Mercury-induced reversible increase in 2,3-diphosphoglycerate phosphatase and concomitant decrease in mutase activity of animal phosphoglycerate mutases. (1967) (18)
Formation of an active phosphoenzyme by diphosphoglycerate-dependent phosphoglyceromutases from muscle, kidney and yeast. (1972) (18)
Studies on the mechanism of action of phosphoglyceromutases. (1961) (18)
Location of a very active bicarbonate-dependent ATPase in the outer membrane of rat and frog liver mitochondria. (1974) (17)
Developmental increases in activity and sensitivity to mercury of human and chicken skeletal muscle phosphoglycermutase. (1970) (17)
Determination of intracellular ATP in primary cultures of neurons. (1997) (17)
Carbamylation of brain proteins with cyanate in vitro and in vivo. (1974) (17)
THE INFLUENCE OF SULFHYDRYL GROUPS ON THE STABILITY OF CARBAMYLPHOSPHATE SYNTHETASE. (1964) (17)
The mechanism of triosephosphate dehydrogenase inactivation by reduced diphosphopyridine nucleotide. (1962) (17)
Scope of the ATP—ubiquitin system for intracellular protein degradation (1982) (16)
Incorporation of hydropyrimidine derivatives in ribonucleic acid with liver preparations. (1958) (16)
Inactivation of Enzymes by Therapeutic Concentrations of Aspirin and Salicylate (1969) (16)
Ammonium ingestion prevents depletion of hepatic energy metabolites induced by acute ammonium intoxication. (1991) (16)
Purification and properties of acyl phosphatase from heart muscle. Comparative properties of acyl phosphatase from several sources. (1971) (16)
Homocitrulline formation following carbamylation of histones with carbamyl phosphate (1971) (16)
Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy (2012) (16)
Studies on the mechanism of action of carbamate kinase. (1962) (15)
[65] Phosphoglycerate mutase from wheat germ (2,3-PGA-independent) (1975) (15)
The potentiating effect of digitoxin and quinidine on dinitrophenol uncoupling of oxidative phosphorylation. (1955) (15)
Enzymic decomposition of the active intermediate in citrulline synthesis. (1954) (15)
CARBON DIOXIDE FIXATION IN ISOCITRIC ACID (1947) (14)
Protective effect of ethanol on acute ammonia intoxication in mice. (1982) (14)
Analysis by flow cytometry of rat hepatocytes from different acinar zones. (1987) (14)
Inactivation of muscle triosephosphate dehydrogenase by reduced diphosphopyridine nucleotide at physiological concentrations. (1962) (14)
Acute and chronic effects of carbamyl glutamate on blood urea and ammonia (2004) (14)
Phosphoryl intermediates formed with phosphoglycerate mutase. Role and labilization of 2,3-diphosphoglycerate. (1966) (14)
Effects of ammonia on synaptosomal membranes. (1984) (14)
High ammonia levels decrease brain acetylcholinesterase activity both in vivo and in vitro. (1994) (13)
Comparative studies in vivo and in vitro of rat-liver enzymes. (1974) (13)
Differential effects of the protein kinase C inhibitors H7 and calphostin C on the cell cycle of neuroblastoma cells (1992) (13)
Effects of urease-induced hyperammonemia in mouse liver (1984) (13)
Synthesis of carbamoyl phosphate by carbamoyl phosphate synthetase I in the absence of acetylglutamate. Activation of the enzyme by cryoprotectants. (1981) (13)
Contribution of hydrouracil and its derivatives to pyrimidine biosynthesis. I. Scope of contribution and some properties of the incorporating system. (1959) (13)
Cell-free synthesis and processing of a large precursor of glutamate dehydrogenase of rat liver. (1982) (13)
Crystalline carbamate kinase. (1966) (13)
The precursor of rat liver mitochondrial glutamate dehydrogenase has enzymatic activity. (1983) (13)
Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity (2012) (13)
INCORPORATION OF DIHYDROURIDINE MONOPHOSPHATE AND URIDINE MONOPHOSPHATE INTO LIVER AND BRAIN RIBONUCLEIC ACID. (1964) (13)
Carbamyl transfer with mammalian and bacterial enzymic preparations. (1955) (13)
Autophagy of ferritin incorporated into the cytosol of HeLa cells by liposomes (2004) (12)
Crystalline ornithine transcarbamylase. (1967) (12)
INDUCTION OF CARBAMYL-P SPECIFIC OXAMATE TRANSCARBAMYLASE BY PARABANIC ACID IN A STREPTOCOCCUS. (1965) (12)
Binding of 2,3‐diphosphoglycerate to normal and abnormal oxyhemoglobin (1970) (12)
Ethical and Legal Aspects (1999) (12)
Limited proteolysis reveals low-affinity binding of N-acetyl-L-glutamate to rat-liver carbamoyl-phosphate synthetase (ammonia). (1987) (12)
Further purification and properties of brain acyl phosphatase. (1960) (12)
On the mechanism of enzymatic hydrolysis of carbamyl phosphate (1971) (12)
On the Biological and Chemical Reactivity of Carbamylated Glucagon 1 (1972) (12)
Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity (1990) (11)
ENZYMATIC SYNTHESIS OF ACETYL PHOSPHATE AND FORMYL PHOSPHATE BY CARBAMYL PHOSPHATE SYNTHETASE. (1964) (11)
Participation of the inner mitochondrial membrane in the inactivation of carbamyl phosphate synthase and of adenosine triphosphatase by lysosomes. (1980) (11)
Carbon dioxide and ammonia fixation in the biosynthesis of citrulline. (1951) (11)
Substrate-induced changes in reactivity of sulfhydryl groups of carbamyl phosphate synthetase. (1966) (11)
TREATMENT OF HEPATOCEREBRAL INTOXICATION (1958) (11)
Effects of prenatal and postnatal alcohol intake on brain development (1985) (11)
Transport and regulation of polypeptide precursors of mature mitochondrial proteins. (1984) (11)
Activation of NMDA receptor mediates the toxicity of ammonia and the effects of ammonia on the microtubule-associated protein MAP-2. (1993) (11)
Acetylornithine synthesis from acetyl phosphate with animal enzymes. (1962) (11)
Exit of proteins and fragments thereof from mitochondria is accelerated by the import of cytosolic synthesized proteins. (1983) (11)
Inactivation of metalloenzymes by salicylate (1970) (11)
Hyperammonemia decreases body fat content in rat (1989) (11)
Inhibition of lactic dehydrogenase and of pyruvate kinase by low concentrations of quercetin. (1975) (11)
Effects of N‐Acetyl Aspartate, Aspartate, and Glutamate on cAMP and cGMP Levels in Developing Rat Cerebral Cortex (1982) (11)
Inhibition of proteolysis of cytosol proteins by lysosomal proteases and of mitochondria of rat liver by antibiotics. (1977) (10)
[47] Enzymatic citrulline synthesis: Ornithine+CO2+NH3→Citrulline (1955) (10)
On the mechanism of the protective effect of ethanol against ammonia intoxication in mice. (1982) (10)
Apparent change in reaction mechanism of phosphoglycerate mutase induced by salt. (1966) (10)
Caffeine-induced changes in the composition of the free amino acid pool of the cerebral cortex (1985) (10)
ENERGY‐GENERATING SYSTEMS (1959) (10)
Acetyl phosphate utilization with animal and bacterial enzymes. (1962) (10)
Letter: Hypoxia, saffron, and cardiovascular disease. (1974) (9)
Inactivation of alcohol and retinol dehydrogenases by acetaldehyde and formaldehyde. (1975) (9)
Acetyl and carbamyl phosphate utilization with aspartate transcarbamylase and carbamate kinase (1963) (9)
Study of carbon dioxide fixation in the synthesis of citrulline. (1948) (9)
Spermidine and spermine stimulate the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria. (1987) (9)
Fate of deutero-labeled carbamyl glutamate in citrulline biosynthesis. (1954) (9)
Prevention of the acute neurotoxic effects of phenytoin on rat peripheral nerve by H7, an inhibitor of protein kinase C. (1992) (9)
Enzymatic synthesis and isolation of 2,3-diphosphoglycerate. (1958) (9)
Effects of hyperammonemia on brain protein kinase C substrates (1996) (9)
Ammonium chloride-induced alterations in growth kinetics and ultrastructure of murine neuroblastoma cells (1986) (8)
Application of the induced-transport test to the mechanism of pig-kidney phosphoglyceromutase. (1973) (8)
H7, an inhibitor of protein kinase C, prevents serum-induced phosphorylation of Raf and MAP kinase in neuroblastoma cells (1996) (8)
On the mechanism of activation of acetyl glutamic acid. (1957) (8)
THE EFFECT OF IONIC STRENGTH ON REACTIONS CATALYZED BY CARBAMYLPHOSPHATE SYNTHETASE. (1965) (8)
Paradoxical protection of both protein-free and high protein diets against acute ammonium intoxication. (1988) (8)
Biosynthetic and structural relationships of compound X and carbamyl phosphate. (1955) (8)
Preparation of glutamate and carbamyl glutamate selectively labeled with deuterium. (1954) (8)
Carbamyl glutamate prevents the potentiation of ammonia toxicity by sodium benzoate (1989) (8)
Inactivation of carbamoyl phosphate synthetase (ammonia) by elastase as a probe to investigate binding of the substrates. (1983) (7)
Dissociation of respiration and enzymatic synthesis of citrulline. (1951) (7)
Turnover and degradation of mitochondria and their proteins. (1979) (7)
Coenzyme binding to glyceraldehyde-3-phosphate dehydrogenase after modification by substrate and coenzyme (1965) (7)
Inhibition of protein synthesis in cell cultures by vanadate and in brain homogenates of rats fed vanadate. (1981) (7)
Selective regional distribution of tubulin induced in cerebrum by hyperammonemia (1989) (7)
Binding of 2,3‐diphosphoglycerate (2,3 DPGA) to hemoglobin Isolation of peptides containing firmly bound 2,3 DPGA (1969) (7)
Turnover of Adenosine Triphosphatase from Rat Liver MitochondriaM (1982) (7)
Degradation of short‐lived proteins is decreased by centrifugation (1982) (7)
[9] Uracil and thymine reductases (1967) (7)
Potentiation of hyperammonemia by sodium benzoate in animals. A note of caution (1982) (6)
H7, a protein kinase C inhibitor, increases the glutathione content of neuroblastoma cells (1992) (6)
Protection against toxic effects of formaldehyde in vitro, and of methanol or formaldehyde in vivo, by subsequent administration of SH reagents. (1976) (6)
Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: possible effect on mitochondrial membranes. (1989) (6)
Loading rat liver mitochondria with apocytochrome c provokes exit of cytochrome c. (1988) (6)
Vanadate, alcohol of both increase passive membrane permeability of Neuro-2a cells; lesser sensitivity of HEp-2 cells. (1981) (6)
Activation of carbamoyl phosphate synthase by N-acetyl-L-aspartate. (1974) (6)
Levels of carbamoyl phosphate synthetase I in livers of young and old rats assessed by activity and immunoassays and by electron microscopic immunogold procedures. (1990) (6)
Contribution of hydr ouracil and its derivatives to pyrimidine biosynthesis. II. Mechanism studies. (1959) (6)
Effect of starvation on the N‐acetylglutamate system of rat liver (1983) (6)
Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy (1993) (6)
Assembly and disassembly of brain tubulin is affected by high ammonia levels (1989) (6)
Protein kinase C isoforms and cell proliferation in neuroblastoma cells. (1996) (6)
Hg2+-induced dissociation of exchange reactions from catalytic activity of 2,3-diphosphoglycerate-dependent phosphoglyceromutases. (1968) (6)
2,3-Bisphosphoglycerate protects mitochondrial and cytosolic proteins from proteolytic inactivation. (1987) (6)
Possible interpretation and extrapolation of heating experiments with enzymes in the presence of substrates or cofactors. (1960) (5)
Increased susceptibility of carbamylated glutamate dehydrogenase to proteolysis. (1977) (5)
AGE-DEPENDENT SENSITIVITY TO SALICYLATE (1975) (5)
Inhibition of proliferation of primary cell cultures and of L-132 cells by protein kinase inhibitors (1993) (5)
A sensitive and specific method for quantitative estimation of carbamylation in proteins. (1974) (5)
Apocytochrome-c competes with pre-ornithine carbamoyl transferase for transport into mitochondria. (1987) (5)
Rats that consume caffeine show decreased brain protein synthesis (2004) (5)
Some enzymic actions on hydrouracil derivatives. (1960) (5)
Hyperammonemia induces polymerization of brain tubulin (1990) (5)
5'-adenosine monophosphate inhibits ternary complex formation by rat liver eIF-2. (1987) (5)
Isolation of a mitochondrial factor from rat liver which potentiates the inactivation of glutamate dehydrogenase by lysosomes. (1981) (5)
Purine nucleotides stimulate while carbamoyl phosphate protects inactivation of ornithine transcarbamoylase by disrupted lysosomes. (1985) (5)
Effect of carbamyl phosphate on stability of some enzymes of the urea cycle; high sensitivity of glutamate dehydrogenase (1972) (5)
Normal values of red cell 2,3-diphosphoglycerate by a simplified automated method. (1970) (5)
A simple and rapid procedure for the preparation of phosphopyruvate hydratase free from phosphoglycerate phosphomutase and pyruvate kinase. (1968) (5)
Monoclonal antibodies used in immunocytochemical localization by electron microscopy of carbamoyl phosphate synthetase I in liver from rats fed high-protein diets. (1987) (5)
N-Formyl-methionine deformylase of animal tissues. (1977) (5)
Mitochondrial protein degradation (1979) (4)
Protein kinase C inhibitors, H7 and calphostin C, inhibit induction of DNA synthesis by cytosolic extracts of exponentially growing neuroblastoma cells in isolated nuclei (1994) (4)
High reactivity of kidney preparations from man, pig, beef, dog and rat for carbamyl phosphate hydrolysis (1974) (4)
Some biochemical properties of lyophilized mitochondria. (1958) (4)
Sulfhydryl inhibitors and enzyme-substrate interactions of carbamyl phosphate synthetase. (1970) (4)
Hyperammonemia induces brain tubulin. (1990) (4)
Activation of carbamoyl phosphate synthetase by cryoprotectants (2004) (4)
H7, an inhibitor of protein kinase C, inhibits tumour cell division in mice bearing ascitic Ehrlich's carcinoma. (1994) (4)
Intracellular degradation of mitochondrial enzymes. (1981) (4)
Exclusion of cyanate as intermediate in ornithine transcarbamoylase action. (1971) (4)
2,3‐Bisphosphoglycerate inhibits ATP‐stimulated proteolysis (1987) (4)
Carbamylation of glutamate dehydrogenase and other mitochondrial proteins by biosynthetic carbamyl phosphate. (1975) (4)
ENZYMATIC DECARBAMYLATION OF CARBAMYL β-ALANINE AND CARBAMYL β-AMINOISOBUTYRIC ACID (1958) (4)
Transport of the precursor for rat liver glutamate dehydrogenase into mitochondria "in vitro". (1983) (4)
Homogeneity among mitochondria revealed by a constant proportion of their enzymes (2004) (4)
Autoradiographic evidence of increased incorporation of aspartate and of carbamoyl aspartate in fibroblasts from a Lesch-Nyhan patient. (1979) (4)
Binding of 2,3-Diphosphoglycerate (DPG) to Oxyhemoglobin; Levels and Effect of DPG on Oxygen Affinity of Normal and Abnormal Blood (1970) (3)
Control of urea synthesis and ammonia detoxification. (1993) (3)
Some stability effects of ATP, Mg++, and dinitrophenol on actomyosin and myosin adenosinetriphosphatase (1960) (3)
Mapping the human genome. (1989) (3)
Influence of substrate-induced enzymic inactivation on the sulfhydryl content of glyceraldehyde-3-phosphate dehydrogenase. (1966) (3)
The purification and properties of reduced diphosphopyridine nucleotide oxidase from uninfected and T2 infected Escherichia coli B. (1962) (3)
ASPIRINS AND ENZYMES (1968) (3)
Correlation between in vivo and in vitro metabolic measurements. Maximum capacity for urea synthesis. (1975) (3)
Adenosine mono-, di- and triphosphate, pyruvic kinase, hexokinase and polynucleotide phosphorylase assay. (1958) (3)
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