Steven j. Burakoff
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(Suggest an Edit or Addition)Steven j. Burakoff's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. (1992) (747)
- Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. (1982) (742)
- Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. (1990) (634)
- Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon (1983) (589)
- The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions. (1983) (572)
- A Comparative Analysis of the Phosphoinositide Binding Specificity of Pleckstrin Homology Domains* (1997) (487)
- Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon (1983) (468)
- Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. (1984) (403)
- B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes. (1988) (381)
- Structure and ligand recognition of the phosphotyrosine binding domain of Shc (1995) (377)
- Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation. (1998) (330)
- Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes (1995) (318)
- Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation. (1993) (316)
- Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase (1999) (292)
- The biologic roles of CD2, CD4, and CD8 in T-cell activation. (1989) (291)
- CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1 (1991) (280)
- Monoallelic expression of the interleukin-2 locus. (1998) (244)
- Immunophilins in protein folding and immunosuppression 1 (1994) (239)
- LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation. (1984) (236)
- Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+. (1982) (227)
- Severe colitis in mice with aberrant thymic selection. (1995) (208)
- Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness. (1996) (198)
- Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect. (2001) (198)
- Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor (1985) (191)
- Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor (1988) (190)
- Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease. (1991) (189)
- NFATc2-mediated repression of cyclin-dependent kinase 4 expression. (2002) (185)
- Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. (1993) (178)
- Interaction of Shc with Grb2 regulates association of Grb2 with mSOS (1995) (178)
- Cytolytic pathways in haematopoietic stem-cell transplantation (2002) (168)
- Radioimmunotherapy with alpha-particle-emitting immunoconjugates. (1988) (161)
- Expression and function of CD8 in a murine T cell hybridoma (1987) (160)
- Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells (1994) (158)
- The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation. (1994) (151)
- SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness. (2004) (149)
- Sialophorin, a surface sialoglycoprotein defective in the Wiskott- Aldrich syndrome, is involved in human T lymphocyte proliferation (1987) (146)
- Lipid Raft Distribution of CD4 Depends on its Palmitoylation and Association with Lck, and Evidence for CD4-Induced Lipid Raft Aggregation as an Additional Mechanism to Enhance CD3 Signaling1 (2003) (145)
- Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott–Aldrich syndrome (1991) (145)
- Involvement of Proteasomes in Regulating Jak-STAT Pathways upon Interleukin-2 Stimulation* (1997) (145)
- Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells. (1978) (145)
- Wnt‐1 and Wnt‐4 regulate thymic cellularity (2002) (138)
- Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease. (1994) (137)
- Inhibition of CD4+ T cell function by the HIV envelope protein, gp120. (1988) (137)
- Cytosolic Tyrosine Dephosphorylation of STAT5 (2000) (136)
- The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma (1984) (134)
- T cell adhesion molecules (1988) (134)
- Specificity of OKT4+ cytotoxic T lymphocyte clones. (1982) (133)
- Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. (1991) (130)
- Rapamycin and FK506 binding proteins (immunophilins) (1991) (123)
- Determination of junction avidity of cytolytic T cell and target cell. (1986) (121)
- The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. (1993) (120)
- Spontaneous aggregation as a mechanism for human monocyte purification. (1986) (113)
- Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling. (1996) (112)
- Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase. (1997) (111)
- Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo (1997) (110)
- Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease. (2002) (109)
- The Extracellular Signal-regulated Kinase Pathway Is Required for Activation-induced Cell Death of T Cells* (1999) (109)
- Expression and function of CD4 in a murine T-cell hybridoma. (1987) (104)
- The role of the L3T4 molecule in mitogen and antigen-activated signal transduction (1987) (104)
- The Small GTP-Binding Protein Rho Potentiates AP-1 Transcription in T Cells (1998) (104)
- Direct evidence for binding of CD8 to HLA class I antigens (1989) (102)
- T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation. (1989) (101)
- Irradiated B7-1 transduced primary acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML. (1996) (99)
- Identification of a Physical Interaction between Calcineurin and Nuclear Factor of Activated T Cells (NFATp) (*) (1996) (98)
- Cytolytic thymus-derived lymphocytes specific for allogeneic stimulator cells crossreact with chemically modified syngeneic cells. (1977) (98)
- Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas (1992) (97)
- LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes. (1985) (94)
- Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation. (1988) (91)
- Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity. (2000) (89)
- Immunodeficiency in graft-versus-host disease. I. Mechanism of immune suppression. (1988) (88)
- p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation. (1992) (88)
- Heritable lymphocyte function-associated antigen-1 deficiency: abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1. (1985) (86)
- Absence of Mitochondrial Superoxide Dismutase Results in a Murine Hemolytic Anemia Responsive to Therapy with a Catalytic Antioxidant (2001) (85)
- Adhesion receptors in lymphocyte activation. (1994) (85)
- Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes. (1985) (84)
- T‐Lymphocyte Activation: The Biology and Function of CD2 and CD4 (1989) (83)
- Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA‐1 membrane molecule (1986) (82)
- Evidence that large granular lymphocytes of donor origin mediate acute graft-versus-host disease. (1989) (82)
- CD43-specific Activation of T Cells Induces Association of CD43 to Fyn Kinase* (1996) (80)
- Targeting Src Homology 2 Domain-Containing Tyrosine Phosphatase (SHP-1) into Lipid Rafts Inhibits CD3-Induced T Cell Activation (2001) (78)
- The effect of the immunosuppressant FK‐506 on alternate pathways of T cell activation (1991) (77)
- FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells (1995) (76)
- Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer. (1983) (76)
- Crk Interacts with Tyrosine-phosphorylated p116 upon T Cell Activation (*) (1995) (75)
- Evidence for differential intracellular signaling via CD4 and CD8 molecules (1994) (75)
- Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. (1995) (74)
- Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. (1992) (74)
- SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling. (1999) (73)
- Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity. (1983) (73)
- Interferon-gamma induction of LFA-1-mediated homotypic adhesion of human monocytes. (1986) (72)
- Protein kinase C required for cytotoxic T lymphocyte triggering. (1987) (71)
- Construction, expression and recognition of an H—2 molecule lacking its carboxyl terminus (1984) (71)
- T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition. (1985) (70)
- Disruption of the CD4-p56lck complex is required for rapid internalization of CD4. (1992) (69)
- Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. (1996) (68)
- Cutting Edge: Gab2 Mediates an Inhibitory Phosphatidylinositol 3′-Kinase Pathway in T Cell Antigen Receptor Signaling1 (2000) (68)
- From Bytes to Bedside: Data Integration and Computational Biology for Translational Cancer Research (2007) (68)
- The induction of cytolytic T lymphocytes with purified plasma membranes. (1978) (67)
- T Cell Activation through the CD43 Molecule Leads to Vav Tyrosine Phosphorylation and Mitogen-activated Protein Kinase Pathway Activation* (1998) (67)
- Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells (1976) (67)
- Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice. (1996) (67)
- Amelioration of acute graft vs host disease due to minor histocompatibility antigens by in vivo administration of anti-interleukin 2 receptor antibody. (1986) (66)
- Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex. (1976) (66)
- Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease. (1986) (65)
- Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens. (1984) (65)
- Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles. (1978) (65)
- Long-lasting deficit of functional T cell precursors in human bone marrow transplant recipients revealed by limiting dilution methods. (1986) (63)
- The role of calcineurin in lymphocyte activation. (2000) (63)
- HIV-gp120 can block CD4-class II MHC-mediated adhesion. (1990) (61)
- Binding Affinities of Tyrosine-phosphorylated Peptides to the COOH-terminal SH2 and NH-terminal Phosphotyrosine Binding Domains of Shc (*) (1996) (61)
- CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity (1995) (59)
- Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma (1985) (59)
- Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules. (1984) (58)
- Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease. (2014) (58)
- Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation. (1988) (58)
- Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases. (1998) (57)
- Graft-vs.-host disease : immunology, pathophysiology, and treatment (1990) (57)
- Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. (1993) (57)
- Tyrosine-phosphorylated Cbl binds to Crk after T cell activation. (1996) (57)
- Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3. (1987) (57)
- Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants (1985) (56)
- Signaling T‐Cell Survival and Death by IL‐2 and IL‐15 (2005) (56)
- Cytotoxic T lymphocytes specific for I region determinants do not require interactions with H-2K or D gene products (1977) (56)
- Alpha and beta subunits of the LFA‐1 membrane molecule are involved in human monocyte–endothelial cell adhesion (1987) (56)
- Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing. (1981) (56)
- Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule. (1988) (55)
- Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4 (2000) (55)
- Acute cutaneous graft-versus-host disease to minor histocompatibility antigens in a murine model. Evidence that large granular lymphocytes are effector cells in the immune response. (1986) (55)
- CD43-mediated Signals Induce DNA Binding Activity of AP-1, NF-AT, and NFκB Transcription Factors in Human T Lymphocytes* (2000) (54)
- CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction. (1987) (54)
- The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. (1995) (54)
- Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients. (1987) (54)
- Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures. (1986) (53)
- Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. (1995) (53)
- Cellular interactions in the generation of cytolytic T lymphocyte responses: role of Ia-positive splenic adherent cells in presentation in H-2 antigen. (1980) (53)
- A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen. (1992) (53)
- The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development. (1998) (52)
- A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. (1993) (50)
- ENGRAFTMENT FOLLOWING T‐CELL‐DEPLETED MARROW TRANSPLANTATION: I. THE ROLE OF MAJOR AND MINOR HISTOCOMPATIBILITY BARRIERS (1987) (49)
- Alpha particle radio-immunotherapy: animal models and clinical prospects. (1989) (49)
- Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. (1985) (49)
- Cellular interactions in the generation of cytolytic T lymphocyte responses Analysis of the helper T cell pathway (1981) (49)
- Site-directed mutagenesis of class I HLA genes. Role of glycosylation in surface expression and functional recognition (1987) (49)
- Cytotoxic T lymphocyte recognition of transfected cells expressing a cloned retroviral gene (1983) (48)
- The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. II. Evidence for antigen-specific suppressor T cells. (1979) (46)
- Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T lymphocytes after gene transfer into human and monkey, but not mouse, cells. (1984) (45)
- Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. (1993) (44)
- Rapamycin-resistant Proliferation of CD8+ T Cells Correlates with p27kip1 Down-regulation and bcl-xL Induction, and Is Prevented by an Inhibitor of Phosphoinositide 3-Kinase Activity* (2004) (43)
- Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement. (1974) (43)
- Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells (1995) (42)
- Hematopoietic Progenitor Kinase 1 Is a Negative Regulator of Dendritic Cell Activation (2009) (42)
- Evidence that anti-LFA-1 in vivo improves engraftment and survival after allogeneic bone marrow transplantation. (1990) (42)
- Genetic control of cytolytic T lymphocyte responses. III. The role of K and I region alleles on the specificity of the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. (1979) (41)
- Prevention of HIV-1 infection and preservation of CD4 function by the binding of CPFs to gp120. (1990) (41)
- Regulation of Cbl Molecular Interactions by the Co-receptor Molecule CD43 in Human T Cells* (2001) (41)
- Expression and ontogeny of CD2 on murine B cells. (1990) (41)
- Species-restricted recognition of transfected HLA-A2 and HLA-B7 by human CTL clones. (1986) (41)
- T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes (1979) (40)
- Role of syngeneic Ia+ accessory cells in the generation of allospecific CTL responses. (1982) (40)
- CD4 and signal transduction. (1996) (39)
- Uncoupling p70s6 Kinase Activation and Proliferation: Rapamycin-Resistant Proliferation of Human CD8+ T Lymphocytes1 (2001) (38)
- The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells. (1978) (38)
- Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response (2009) (38)
- HIV Nef-Mediated CD4 Down-Regulation Is Adaptor Protein Complex 2 Dependent1 (2005) (37)
- Alloreactivity studied with mutants of HLA-A2. (1989) (37)
- Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. (1990) (37)
- Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny. (1996) (36)
- T cell receptors: adhesion and signaling. (1991) (36)
- Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density (1987) (34)
- A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase. (2000) (34)
- Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes. (1991) (34)
- Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions. (1986) (34)
- Requirement for three distinct lymphokines for the induction of cytotoxic T lymphocytes from thymocytes. (1986) (33)
- HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent (2006) (33)
- Lysine 144, a Ubiquitin Attachment Site in HIV-1 Nef, Is Required for Nef-Mediated CD4 Down-Regulation1 (2008) (33)
- Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity* (1999) (33)
- HPK1 as a novel target for cancer immunotherapy (2012) (33)
- Requirement for Shc in TCR-mediated activation of a T cell hybridoma. (1999) (32)
- Effect of Anti‐IL‐2Rα Antibody on IL‐2‐induced Jak/STAT Signaling (2002) (32)
- Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation. (1993) (32)
- Differential activation of phosphotyrosine protein phosphatase activity in a murine T cell hybridoma by monoclonal antibodies to CD45. (1992) (31)
- Nicotine Activates Nuclear Factor of Activated T Cells c2 (NFATc2) and Prevents Cell Cycle Entry in T Cells (2004) (30)
- Development and characterization of allospecific long-term human cytolytic T-cell lines. (1980) (30)
- Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice (1982) (30)
- Nuclear factors that mediate intrathymic signals are developmentally regulated (1994) (30)
- Analysis of the two-signal requirement for precursor cytolytic T lymphocyte activation using H-2Kk in liposomes. (1982) (30)
- Is the primary complement lesion insufficient for lysis? Failure of cells damaged under osmotic protection to lyse in EDTA or at low temperature after removal of osmotic protection. (1975) (29)
- Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5. (1988) (29)
- Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors. (1986) (29)
- Production of colony-stimulating factor(s) for granulocyte-macrophage and multipotential (granulocyte/erythroid/megakaryocyte/macrophage) hematopoietic progenitor cells (CFU-GEMM) by clonal lines of human IL-2-dependent T-lymphocytes. (1984) (28)
- The human HLA specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the α2 domain of murine H-2Db (2004) (27)
- Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens. (1977) (27)
- Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. (1994) (27)
- Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4. (1990) (27)
- Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line. (1983) (27)
- Inhibition of lymphokine-activated killer cell-mediated cytotoxicity by phorbol ester. (1989) (27)
- Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells (1978) (27)
- FK 506 and rapamycin: molecular probes of T-lymphocyte activation. (1991) (26)
- Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction. (1990) (26)
- Analysis of cross-reactive antigen-specific T cell clones. Specific recognition of two major histocompatibility complex (MHC) and two non- MHC antigens by a single clone (1983) (26)
- Functional distinctions between the LFA-1, LFA-2, and LFA-3 membrane proteins on human CTL are revealed with trypsin-pretreated target cells. (1985) (26)
- Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase. (2000) (26)
- The induction of secondary cytolytic T lymphocytes by solubilized membrane proteins (1978) (25)
- Generation of long-term human cytolytic cell lines with persistent natural killer activity. (1982) (25)
- The function of LFA-1 in cell-mediated killing and adhesion: studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation. (1985) (25)
- Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens (1980) (25)
- Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription. (2003) (25)
- Prostaglandin E2 Activates HPK1 Kinase Activity via a PKA-dependent Pathway* (2007) (25)
- Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction. (1990) (25)
- Expression and ontogeny of murine CD2 (1989) (24)
- Dynamic changes in viscoelastic properties in cytotoxic T-lymphocyte-mediated killing. (1988) (24)
- Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin‐mediated killing (2004) (24)
- Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease. (2000) (23)
- Role of the Lck Src Homology 2 and 3 Domains in Protein Tyrosine Phosphorylation* (1996) (23)
- Responses to the H–2Kba mutant involve recognition of syngeneic Ia molecules (1983) (23)
- Interaction of Shc with Grb2 Regulates the Grb2 Association with mSOS (1995) (23)
- T cell surface molecules regulating noncognate B lymphocyte activation. Role of CD2 and LFA-1. (1992) (22)
- The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before. (2019) (22)
- The role of T cell accessory molecules in the generation of class II-specific xenogeneic cytolytic T cells. (1986) (22)
- Antigen-induced unresponsiveness results in altered T cell signaling. (1999) (22)
- A molecular analysis of the cytolytic T lymphocyte response. (1984) (21)
- A Large Proportion of T Lymphocytes Lack CD5 Expression After Bone Marrow Transplantation (1989) (21)
- Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. (1986) (21)
- Coexpression of the human HLA-A2 or HLA-B7 heavy chain gene and human beta 2-microglobulin gene in L cells. (1984) (21)
- Expression and function of a CD 5 cDNA in human and murine T cells (1988) (21)
- Glycolipid-anchored form of CD4 increases intercellular adhesion but is unable to enhance T cell activation. (1991) (21)
- Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domain. (1989) (20)
- Molecular and biological actions of cyclosporin A and FK506 on T cell development and function. (1994) (20)
- Cytotoxic T lymphocytes induced against allogeneic I-region determinants react with Ia molecules on trinitrophenyl-conjugated syngeneic target cells (1977) (20)
- IN VITRO GENERATION OF HELPER T CELLS AND SUPPRESSOR T CELLS THAT REGULATE THE CYTOLYTIC T LYMPHOCYTE RESPONSE TO TRINITROPHENYL‐MODIFIED SYNGENEIC CELLS (1982) (20)
- Recognition of interspecies hybrid class I histocompatibility antigens by antigen-specific cytolytic T lymphocytes. (1985) (20)
- Lymphocytes with a CD4+ CD8- CD3- phenotype are effectors of experimental cutaneous graft-versus-host disease. (1991) (20)
- A monoclonal antibody to LFA‐3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins (1989) (19)
- T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten- specific cytolytic T lymphocytes (1980) (19)
- CD4 Phosphorylation Partially Reverses Nef Down-Regulation of CD41 (2004) (19)
- Lymphoid irradiation results in long‐term increases in natural killer cells in patients treated for Hodgkin's disease (1992) (19)
- The immune response to Moloney murine leukemia virus-induced tumors: induction of cytolytic T lymphocytes specific for both viral and tumor-associated antigens. (1986) (18)
- Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles. (1980) (18)
- A DC-specific cytolytic T lymphocyte line is OKT8+1. (1983) (18)
- Human Cytolytic T-Lymphocyte Clones and Their Function-Associated Cell Surface Molecules (1985) (17)
- ENGRAFTMENT FOLLOWING T CELL‐DEPLETED BONE MARROW TRANSPLANTATION: III. DIFFERENTIAL EFFECTS OF INCREASED TOTAL‐BODY IRRADIATION ON SEMIALLOGENEIC AND ALLOGENEIC RECIPIENTS (1988) (17)
- Growth-inhibitory activity of lymphoid cell plasma membranes. II. Partial characterization of the inhibitor (1984) (17)
- Expression of CD5 regulates responsiveness to IL-1. (1988) (16)
- CD8 ß chain influences CD8 a chain-associated Lck kinase activity (1995) (16)
- Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. (1993) (15)
- Antigen-specific suppression of cytotoxic T cell responses: an idiotype-bearing factor regulates the cytotoxic T cell response to azobenzenearsonate-coupled cells. (1982) (15)
- ENGRAFTMENT FOLLOWING T‐CELL-DEPLETED BONE MARROW TRANSPLANTATION II. STABILITY OF MIXED CHIMERISM IN SEMIALLOGENEIC RECIPIENTS AFTER TOTAL‐BODY IRRADIATION (1987) (15)
- Evidence that anti-asialo GM1 in vivo improves engraftment of T cell-depleted bone marrow in hybrid recipients. (1990) (15)
- Use of the HLA-DR antigens incorporated into liposomes to generate HLA-DR specific cytotoxic T lymphocytes. (1984) (14)
- FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS (1986) (14)
- Distinct effects of interferon-gamma and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis. (1990) (14)
- A perspective on HPK1 as a novel immuno-oncology drug target (2020) (14)
- T cell hybridomas define the class II MHC-restricted response to vesicular stomatitis virus infection. (1988) (13)
- Biodistribution studies of anti-Thy 1.2 IgM immunoconjugates: implications for radioimmunotherapy. (1988) (13)
- Functional T cell deficits after bone marrow transplantation across minor histocompatibility barriers: effects of graft-vs-host disease on precursor frequency of reactive cells. (1987) (13)
- Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation (2019) (13)
- Intracellular signaling consequences of anti-IL-2Rα blockade by daclizumab (2001) (13)
- The cytoplasmic domain of CD4 is required for stable association with the lymphocyte‐specific tyrosine protein kinase p56lck (1990) (12)
- Thymectomized, irradiated, and bone marrow-reconstituted chimeras have normal cytolytic T lymphocyte precursors but a defect in lymphokine production. (1984) (12)
- Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation. (2013) (12)
- Human lymphocyte function associated antigens (1984) (12)
- Functional expression of human CD8 in fully reconstituted mice after retroviral-mediated gene transfer of hemopoietic stem cells. (1992) (12)
- Specificity of rat xenogeneic cell-mediated cytolysis for the products of the K and D loci of the mouse H-2 complex. (1977) (12)
- Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3. (1990) (12)
- CPF-DD is an inhibitor of infection by human immunodeficiency virus and other enveloped viruses in vitro. (1992) (12)
- Two Sorting Motifs, a Ubiquitination Motif and a Tyrosine Motif, Are Involved in HIV-1 and Simian Immunodeficiency Virus Nef-Mediated Receptor Endocytosis (2011) (11)
- Uncoupling p 70 s 6 Kinase Activation and Proliferation : Rapamycin-Resistant Proliferation of Human CD 8 1 T Lymphocytes 1 (2001) (11)
- Inhibition of the induction of cytolytic T lymphocytes with alloantisera directed against H-2K and H-2D gene products. (1978) (11)
- Cell-mediated immunity to viral glycoproteins. (1980) (11)
- Genetic control of the cytolytic T lymphocyte response to influenza viruses: H-2 genes influence the response to H-2Kb plus virus. (1982) (11)
- Ir gene control of the cytotoxic T lymphocyte response to Sendai virus: H-2k mice are low responders to Sendai. (1981) (11)
- A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation. (1989) (10)
- Acute graft-versus-host disease: pathogenesis and prevention with a monoclonal antibody in vivo. (1987) (10)
- Cytolytic T lymphocyte recognition of subcellular antigen. (1982) (10)
- Alloreactive lymphocytes from T cell receptor (beta-chain) transgenic mice do not mediate a graft-versus-host reaction. (1991) (10)
- The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity. (1988) (9)
- The alpha-3 domain of class I MHC proteins influences cytotoxic T lymphocyte recognition of antigenic determinants located within the alpha-1 and alpha-2 domains. (1988) (9)
- Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase (1999) (8)
- Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model. (2004) (8)
- CD4, CD8 and CD2 in T cell adhesion and signaling. (1993) (8)
- Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni. (1979) (8)
- Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins. (1980) (8)
- Interleukin-3 (IL-3)-induced c-fos Activation Is Modulated by Gab2-Calcineurin Interaction* (2008) (7)
- The interaction of CD4 with HIV-1 gp120. (1991) (7)
- Efficient conjugation of DTPA to an IgM monoclonal antibody in ascites fluid. (1988) (7)
- The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562. (1990) (7)
- The ability of Ia and H‐2Kk‐bearing membranes to replace the antigen‐presenting cell in an H‐2Kkallogeneic cytotoxic T cell response (1985) (7)
- Intracellular signaling consequences of anti-IL-2Ralpha blockade by daclizumab. (2001) (7)
- Coreceptors and Adapter Proteins in T‐Cell Signaling (1995) (6)
- Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes. (1983) (6)
- Phenotypic and functional analysis of expanded natural killer cell subpopulations in Hodgkin's disease patients treated with lymphoid irradiation. (1993) (6)
- Disruption of the CD 4p 56 lck complex is required for rapid internalization of CD 4 ( T-celi activation / receptor inteatio / protein-tyrosine kinae ) (6)
- Recapitulation of the immune response and haematopoietic system in bone marrow transplantation. (1983) (6)
- H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells (1985) (6)
- Inhibition of normal lymphocyte responses by cell membranes. (1984) (6)
- Expression and CTL recognition of cloned subgenomic fragments of moloney murine leukemia virus in murine cells (1985) (5)
- HPK1 Influences Regulatory T Cell Functions (2020) (5)
- Alkylating HIV-1 Nef - a potential way of HIV intervention (2010) (5)
- The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes. (1979) (4)
- Novel subsets of human T cells (CD4+ CD8+ TCRγδ and CD4− CD8− TCRαβ) and T‐cell development (1989) (4)
- The role of functional cell surface antigens in T cell activation. (1986) (4)
- The mechanism of antigen presentation by dendritic cells and splenic adherent cells in the induction of an allogeneic cytotoxic T-lymphocyte response to H-2Kk liposomes. (1986) (4)
- Membrane-bound anti-CD3 monoclonal antibodies trigger cytolytic T-lymphocyte-mediated tumor lysis. (1988) (4)
- Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer. (1984) (4)
- Induction of HLA class I surface expression recruits low-affinity cytolytic T lymphocytes. (1990) (4)
- Specificity of alloreactive T lymphocytes that adhere to lung stage schistosomula of Schistosoma mansoni. (1980) (4)
- Evidence that lfa 3 activates t cells via the cd2 receptor (1987) (3)
- Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells. (1986) (3)
- Transplantation editorial overview Antigen, co-stimulators and cytokines: regulators of allogeneic interactions (1993) (3)
- The role of L3T4 (CD4) in T-cell activation. (1987) (3)
- STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70 (1999) (3)
- Suppression of anti-hapten antibody responses by hapten-specific cytolytic T lymphocytes: role of I-A-associated antigen on target B lymphocytes. (1982) (3)
- Basic science seminar: cytotoxic T-lymphocyte response to HLA antigens. (1983) (3)
- The role of the CD4 (L3T4) molecule in T-cell activation (1987) (2)
- Molecular Characterization of Allospecific Cytotoxic T-Lymphocyte Recognition Sites in the HLA-A2 Molecule Using Oligonucleotide-Generated Site-Specific Mutants (1989) (2)
- Viral-restricted cytolytic T lymphocyte recognition of hybrid human-murine class I histocompatibility antigens. (1986) (2)
- Effect of timing of lymphokine presentation on generation of cytotoxic T lymphocytes. (1989) (2)
- INDUCTION OF VIRUS-SPECIFIC H-2 RESTRICTED MURINE CTL BY LIPOSOMES (1979) (2)
- Distinct roles for L3T4 in T cell activation. (1987) (2)
- A Remembrance of Baruj Benacerraf (AAI '57) 1920–2011 (2011) (2)
- Non-MHC-restricted target-cell lysis by a CD4-CD8- TCR alpha beta T-cell line, as well as by TCR gamma delta T-cell lines, results from lymphokine-activated killing. (1991) (2)
- Evidence for Differential Intracellular Signal ; rig via CD 4 and CD 8 Molecules (2003) (2)
- Cytotoxic T cells directed against HLA-DR antigens and their surface proteins. (1983) (1)
- Site does matter: tumorigenesis of the murine hepatocellular carcinoma cell line Hepa 1–6 is dependent upon intrahepatic rather than subdermal implantation (2003) (1)
- Cancer therapy from bench to bedside. (2010) (1)
- Cellular interactions in the regulation of the cytolytic T-lymphocyte response: the effect of suboptimal antigen dose. (1981) (1)
- Allogeneically sensitized cytolytic t lymphocytes specifically lyse tnp derivatized targets h-2 identical to the effectors. Abstr. (1977) (1)
- Radioimmunotherapy with alpha particle emitting monoclonal antibodies (1987) (1)
- Analysis of CD4 and CD2 receptor function. (1988) (1)
- Mutants of HLA-A2 in the analysis of its structure and function. (1989) (1)
- Experimental evidence for the potential usefulness of permanent IL-3-dependent multipotential hematopoietic progenitor cell lines in transfusion granulocyte support therapy: need for expansion of early passage cells. (1984) (1)
- Hematopoietic progenitor kinase 1 (HPK1) influences regulatory T cell functions (163.26) (2012) (1)
- A CD8/Lck Transgene Is Able to Drive Thymocyte Differentiation1 (2006) (1)
- IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE (1997) (1)
- Human dermal fibroblasts can present antigen to T cells (1984) (1)
- CD 8 / ~ Chain Influences CD 8 ol Chain-associated Lck Kinase Activity (2003) (1)
- Novel subsets of human T cells (CD4+ CD8- TCR gamma delta and CD4- CD8- TCR alpha beta) and T-cell development. (1989) (1)
- Molecular cloning of a membrane-associated human FK 506-and rapamycin-binding protein , FKBP-13 ( rotamase / T-cefl activation / mast cell ) (1)
- responsiveness expression reveal targets of damage, stress response, and antioxidant SOD2-deficiency anemia: protein oxidation and altered protein (2013) (1)
- Positive and negative signaling pathways. (1999) (1)
- Cell Antigen Receptor Signaling-Kinase Pathway in T ′ Phosphatidylinositol 3 Cutting Edge : Gab 2 Mediates an Inhibitory Neel and (2000) (1)
- Book ReviewImmunology Basic and Clinical Immunology (1985) (0)
- Murine CD2: structure, expression, and recognition of human LFA-3. (1989) (0)
- The use of purified H-2 antigens to define the helper T cell pathway involved in cytolytic T lymphocyte induction (1980) (0)
- Involvement of Shc and SHP2 in cytokine signaling (1997) (0)
- Identification of the residues important for the interaction of NFATc3 with calcineurin (1997) (0)
- Abstract A43: Therapeutic efficacy of antitumor monoclonal antibodies combined with chemotherapy depends on innate immunity and NK1.1- innate lymphoid cells. (2013) (0)
- Lipid Raft Distribution of CD4 Depends on (2002) (0)
- Transplantation. Antigen, co-stimulators and cytokines: regulators of allogeneic interactions. (1993) (0)
- Antigenic Requirements for the Recognition of Moloney Murine Leukemia Virus-Induced Tumors by Cytotoxic T Lymphocytes (1987) (0)
- nes allospecific for (2016) (0)
- In vitro generation of helper and suppressor t cells that regulate the cytolytic t lymphocyte response to tnp modified syngeneic cells. Abstr. (1981) (0)
- CD 3-Induced T Cell Activation ( SHP-1 ) into Lipid Rafts Inhibits Domain-Containing Tyrosine Phosphatase Targeting Src Homology 2 (2001) (0)
- Cell Surface Antigens Involved in Human Cytolytic T Lymphocyte-mediated Cytolysis (1985) (0)
- The Role of Co-receptors in T Cell Activation (1993) (0)
- INTRACELLULAR SIGNALING BY THE INTERMEDIATE‐AFFINITY IL‐2R CHAINS AFTER TREATMENT WITH DACLIZUMAB.: Abstract# 1096 (2000) (0)
- Ir GENE CONTROL OF THE CYTOLYTIC T CELL RESPONSE TO INFLUENZA VIRUS (1981) (0)
- Biochemical and functional analyses of a secreted H-2Ld molecule (1986) (0)
- prostaglandin E2-induced fos gene transcription Hematopoietic progenitor kinase 1 (HPK1) negatively regulates (2013) (0)
- HPK1 as a novel target for cancer immunotherapy (2012) (0)
- Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity* (1999) (0)
- Cytotoxic t lymphocytes mediate graft rejection following bone marrow transplantation (1986) (0)
- Down-Regulation of CD4 CD4 Phosphorylation Partially Reverses Nef (2004) (0)
- Involvement of Syngeneic Ia in T Cell Responses to Class I Alloantigens (1983) (0)
- 520 Magnetic resonance imaging of a murine model for hepatocellular carcinoma (2003) (0)
- ALLOPEPTIDE/MHC‐TCR AFFINITY DETERMINES PHOSPHORYLATION KINETICS.: Abstract# 77 (2000) (0)
- Modified ia antigens on target b lymphocytes in the cytolytic t lymphocyte mediated suppression of anti hapten antibody responses (1982) (0)
- Cytolytic T lymphocyte response to moloney sarcoma virus (1983) (0)
- .(major histocompatibility antigens/gene doning/specificity of cytotoxi (2016) (0)
- Long-term human cytolytic T-cell lines allospecific for HLA-DR 6 antigen are OKT 4 ' ( cytotoxic T lymphocyte / DR specificity / surface antigens ) (0)
- The ontogeny of t-cell sets specific for allo- antigens or modified self antigens. (1978) (0)
- Immune gene expression in primary melanomas to predict lower risk of recurrence and death. (2013) (0)
- Nef-Mediated Receptor Endocytosis and Simian Immunodeficiency Virus and a Tyrosine Motif, Are Involved in HIV-1 Two Sorting Motifs, a Ubiquitination Motif (2011) (0)
- Ir Gene Control of Cytolytic T Lymphocytes Induced by TNP Modified Syngeneic Cells in Normal and Chimeric Mice (1978) (0)
- N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70 (1999) (0)
- ALLOANTIGEN-UNRESPONSIVENESS RESULTS IN DEFECTS IN INTRACELLULAR SIGNALING AND TRANSCRIPTIONAL ACTIVATION OF THE IL-2 PROMOTER. (1999) (0)
- Contents, Vol. 91, 1990 (1990) (0)
- Peptides antiviraux a terminaisons bloquees (1991) (0)
- Thymocyte Differentiation A CD8/Lck Transgene Is Able to Drive (2006) (0)
- Enhance CD 3 Signaling Aggregation as an Additional Mechanism to and Evidence for CD 4-Induced Lipid Raft its Palmitoylation and Association with Lck , Lipid Raft Distribution of CD 4 Depends on (2002) (0)
- Alterations in natural killer subsets in patients treated for Hodgkin's disease (1986) (0)
- Fas-Deficientlpr Mice Are More Susceptible to Graft-Versus-Host Disease (1999) (0)
- SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE (1997) (0)
- Mixed chimerism production by nonmyeloablative bone marrow transplantation in a mouse model (2003) (0)
- Cell-mediated cytotoxicity. An overview. (1984) (0)
- Genetic Regulation of the Cytolytic T Lymphocyte Response to Influenza Viruses (1983) (0)
- Intracellular signals associated with in vivo T cell anergy (1997) (0)
- ALLOANTIGEN-UNRESPONSIVENESS IS ASSOCIATED WITH EARLY TCR SIGNALING DEFECTS IN VIVO (1998) (0)
- ROLE OF SYNGENEIC la' ACCESSORY CELLS IN THE CTL RESPONSES GENERATION OF ALLOSPECIFIC (1982) (0)
- Allospecific andvirus-specific cytolytic Tlymphocytes are restricted totheNorC1domainofH-2antigens expressed onLcells after DNA-mediated genetransfer (1983) (0)
- Assays of Cell-mediated Cytotoxicity (2003) (0)
- association of Grb2 with mSOS. Interaction of Shc with Grb2 regulates (2013) (0)
- Methods for the detection, purification, and biochemical characterization of lymphoid cell surface antigens (1984) (0)
- to Graft-Versus-Host Disease Mice Are More Susceptible lpr Fas-Deficient (1999) (0)
- The role of CD8β in T cell development may be due to its regulation of CD8α-associated Lck kinase activity (1997) (0)
- Expression of the cytokine interleukin-2 is controlled by allelic exclusion (1998) (0)
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