S. Morris Kupchan

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S. Morris Kupchan

Chemistry

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Organic Chemistry

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#382

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Chemistry

S. Morris Kupchan's Degrees

Bachelors Chemistry Stanford University

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S. Morris Kupchan's Published Works

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Published Works

Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii. (1972) (422)
Tumor inhibitors. 69. Structure-cytotoxicity relationships among the sesquiterpene lactones. (1971) (419)
Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus. (1972) (368)
Antimitotic activity of the potent tumor inhibitor maytansine. (1975) (315)
Reactions of Alpha Methylene Lactone Tumor Inhibitors with Model Biological Nucleophiles (1970) (273)
Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica. (1973) (248)
Tumor inhibitors. XLVII. Vernodalin and vernomygdin, two new cytotoxic sesquiterpene lactones from Vernonia amygdalina Del. (1969) (187)
Antileukemic principles isolated from euphorbiaceae plants. (1976) (163)
Taxodione and taxodone, two novel diterpenoid quinone methide tumor inhibitors from Taxodium distichum. (1969) (154)
Steganacin and steganangin, novel antileukemic lignan lactones from Steganotaenia araliacea. (1973) (152)
The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica. (1975) (138)
Jatrophone, a novel macrocyclic diterpenoid tumor inhibitor from Jatropha gossypiifolia (1970) (123)
The maytansinoids. Isolation, structural elucidation, and chemical interrelation of novel ansa macrolides. (1977) (118)
Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis. (1976) (117)
Selective Alkylation: A Biomimetic Reaction of the Antileukemic Triptolides? (1974) (100)
Vernolepin, a novel elemanolide dilactone tumor inhibitor from Vernonia hymenolepis. (1968) (100)
Tumor inhibitors. 48. Taxodione and taxodone, two novel diterpenoid quinone methide tumor inhibitors from Taxodium distichum. (1968) (95)
Psorospermin, a new antileukemic xanthone from Psorospermum febrifugum. (1980) (93)
Tumor inhibitors—XXXIII (1969) (92)
Structure and stereochemistry of jatrophone, a novel macrocyclic diterpenoid tumor inhibitor. (1976) (91)
Mezerein: antileukemic principle isolated from Daphne mezereum L. (1975) (90)
l-Usnic acid: Tumor inhibitor isolated from lichens (1975) (89)
Calotropin, a Cytotoxic Principle Isolated from Asclepias curassavica L (1964) (87)
TUMOR INHIBITORS. I. ARISTOLOCHIC ACID, THE ACTIVE PRINCIPLE OF ARISTOLOCHIA INDICA. (1962) (87)
Inhibition of Phosphofructokinase by Quinone Methide and α-Methylene Lactone Tumor Inhibitors (1970) (86)
Tumor inhibitors. XLV. Crotepoxide, a novel cyclohexane diepoxide tumor inhibitor from Croton macrostachys. (1969) (84)
Structural requirements for antileukemic activity among the naturally occurring and semisynthetic maytansinoids. (2002) (80)
The Isolation and Structural Elucidation of a Novel Steroidal Tumor Inhibitor from Acnistus arborescens1,2 (1965) (78)
Tumor inhibitors. XXXIX. Active principles of Acnistus arborescens. Isolation and structural and spectral studies of withaferin A and withacnistin. (1969) (77)
Tumor inhibitors. XLVI. Vernolepin, a novel sesquiterpene dilactone tumor inhibitor from Vernonia hymenolepis A. Rich. (1969) (75)
Crotepoxide, a novel cyclohexane diepoxide tumor inhibitor from Croton macrostachys. (1968) (68)
Tumor inhibitors. 114. Aloe emodin: antileukemic principle isolated from Rhamnus frangula L. (1976) (68)
Antimitotic and antitubulin activity of the tumor inhibitor steganacin. (1977) (67)
Isolation of potent new antileukemic trichothecenes from Baccharis megapotamica. (1977) (67)
Tumor inhibitors. X. Photochemical synthesis of phenanthrenes. Synthesis of aristolochic acid and related compounds. (1965) (67)
Recent advances in the chemistry of tumor inhibitors of plant origin. (1970) (66)
Beta-Solamarine: Tumor Inhibitor Isolated from Solanum dulcamara (1965) (64)
Tumor inhibitors. VI. Cissampareine, new cytotoxic alkaloid from Cissampelos pareira. Cytotoxicity of bisbenzylisoquinoline alkaloids. (1965) (63)
Isolation and structural elucidation of allamandin, an antileukemic iridoid lactone from Allamanda cathartica. (1974) (63)
Tumor inhibitors. XLI. Structural elucidation of tumor-inhibitory sesquiterpene lactones from Eupatorium rotundifolium. (1969) (60)
Recent advances in the chemistry of terpenoid tumor inhibitors. (1970) (57)
Datiscacin, a novel cytotoxic cucurbitacin 20-acetate from Datisca glomerata. (1973) (55)
Isolation and structural elucidation of new potent antileukemic diterpenoid esters from Gnidia species. (1976) (55)
Tumor inhibitors. LVII. Reaction of endocyclic .alpha.,.beta.-unsaturated .gamma.-lactones with thiols (1970) (54)
Novel nonphenol oxidative coupling. (1973) (50)
Plant anticancer agents. 28. New antileukemic jatrophone derivatives from Jatropha gossypiifolia: structural and stereochemical assignment through nuclear magnetic resonance spectroscopy (1983) (50)
THALICTRUM ALKALOIDS. I. THALICARPINE, A NEW HYPOTENSIVE ALKALOID FROM THALICTRUM DASYCARPUM. (1963) (48)
Baccharin, a novel potent antileukemic trichothecene triepoxide from Baccharis megapotamica. (1976) (47)
Inactivation of glycogen synthase by the tumor inhibitor vernolepin. (1972) (47)
Phyllanthocin, a novel bisabolane aglycone from the antileukemic glycoside, phyllanthoside. (1977) (46)
Letter: Gnididin, gniditrin, and gnidicin, novel potent antileukemic diterpenoid esters from Gnidia lamprantha. (1975) (45)
Maytanprine and maytanbutine, new antileukaemic ansa macrolides from Maytenus buchananii (1972) (45)
Tumor inhibitors XL. The isolation and structural elucidation of elephantin and elephantopin, two novel sesquiterpenoid tumor inhibitors from Elephantopus elatus. (1969) (45)
Tumor inhibitors. XXXII. Isolation and structural elucidation of novel derivatives of aristolochic acid from Aristolochia indica (1968) (44)
Letter: Novel maytansinoids. Naturally occurring and synthetic antileukemic esters of maytansinol. (1975) (44)
The isolation and structural elucidation of eupaserrin and deacetyleupaserrin, new antileukemic sesquiterpene lactones from Eupatorium semiserratum. (1973) (43)
The alkaloids of American lotus, Nelumbo lutea (1963) (40)
Quassimarin, a new antileukemic quassinoid from Quassia amara. (1976) (40)
Structural requirements for tumor-inhibitory activity among benzylisoquinoline alkaloids and related synthetic compounds. (1973) (40)
Maytoline, a nicotinoyl sesquiterpene alkaloid prototype from Maytenus ovatus (1970) (40)
Tumor inhibitors. 8. Eupatorin, new cytotoxic flavone from Eupatorium semiserratum. (1965) (39)
Tumor inhibitors. LXV. Bersenogenin, berscillogenin, and 3-epiberscillogenin, three new cytotoxic bufadienolides from Bersama abyssinica. (1971) (38)
Schoenocaulon Alkaloids. I. Active Principles of Schoenocaulon officinale. Cevacine and Protocevine1,2 (1953) (37)
New cucurbitacins from Phormium tenax and Marah oreganus (1978) (37)
Dehydroailanthinone, a new antileukemic quassinoid from Pierreodendron kerstingii. (1975) (37)
Cytotoxic flavonols from Baccharis sarothroides (1971) (37)
Photochemical synthesis of aporphines. (1971) (37)
Datiscoside, a novel antileukemic cucurbitacin glycoside from Datisca glomerata. (1972) (36)
Eupacunin, a novel antileukemic sesquiterpene lactone from Eupatorium cuneifolium. (1971) (36)
Letter: Gnidimacrin and gnidimacrin 20-palmitate, novel macrocyclic antileukemic diterpenoid esters from Gnidia subcordata1,2. (1976) (36)
Veratrum Alkaloids. XXVIII.1 The Structure and Configuration of Germine2-4 (1959) (36)
Tumor inhibitors. XXXVI. Eupatin and eupatoretin, two cytotoxic flavonols from Eupatorium semiserratum (1969) (36)
MACROCYCLIC SPERMIDINE ALKALOIDS FROM MAYTENUS SERRATA AND TRIPTERYGIUM WILFORDII (1977) (35)
The Isolation and Structural Elucidation of Two Novel Sesquiterpenoid Tumor Inhibitors from Elephantopus elatus1,2 (1966) (34)
The Structure of Cyclobuxine (1962) (34)
Tumor Inhibitors. XXIII.(1) The Cytotoxic Principles of Marah oreganus H.(2). (1967) (34)
Structural elucidation of novel tumor-inhibitory sesquiterpene lactones from Eupatorium cuneifolium. (1973) (33)
New alkaloids and related artifacts from Cyclea peltata. (1973) (32)
Reductive elimination of epoxides to olefins with zinc-copper couple (1971) (32)
Structural requirements for biological activity among antileukemic glaucarubolone ester quassinoids. (1976) (32)
The chemistry and biological activity of derivatives of strophanthidin. (1967) (32)
Toxic Effects of Potato Sprouts and of Solanine Fed to Pregnant Rats (1961) (31)
Buxus alkaloids. XII. Benzamide alkaloids from Buxus sempervirens L. (1967) (31)
Tumor inhibitors. XLIV. The isolation and characterization of hellebrigenin 3-acetate and hellebrigenin 3,5-diacetate, bufadienolide tumor inhibitors from Bersama abyssinica. (1969) (31)
Tumor inhibitors. LVI. Cucurbitacins O,P, and Q, the cytotoxic principles of Brandegea bigelovii. (1970) (30)
The Configuration of Cyclobuxine and its Interrelation with Cycloeucalenol (1962) (30)
The configuration of cevine (1959) (30)
Nuclear magnetic resonance spectra of veratrum alkaloids (1964) (30)
Tumor inhibitors. 126. New cytotoxic neolignans from Aniba megaphylla Mez (1978) (29)
Menispermaceae alkaloids. II. The alkaloids of Cyclea peltata Diels. (1961) (29)
Conformation and reactivity of the macrocyclic tumor-inhibitory alkaloid tetrandrine. (1976) (29)
Structural Elucidation and High-Resolution Mass Spectrometry of Gaillardin, a New Cytotoxic Sesquiterpene Lactone (1966) (29)
Intramolecular nonphenol oxidative coupling of phenethylisoquinolines (1978) (28)
Alkylaminoalkyl Derivatives of 8-Aminoquinoline1 (1946) (28)
Tumor inhibitors. VII. Podophyllotoxin, the active principle of Juniperus virginiana. (1965) (27)
Tumor inhibitors. LXXXI. Structure and partial synthesis of fabacein (1973) (27)
Vernolepin: A New, Reversible Plant Growth Inhibitor (1968) (27)
Veratrum alkaloids. L. Structure-activity relationships in a series of synthetic hypotensive analogs of the protoveratrines. (1962) (27)
The isolation and structural elucidation of a novel naturally-occurring bufadienolide orthoacetate. (1969) (26)
Intramolecular oxidative coupling of monophenolic benzylisoquinolines. Quinonoid oxoaporphines. (1973) (26)
Tumor inhibitors. XLIII. Solapalmitine and solapalmitenine, two novel alkaloid tumor inhibitors from Solanum tripartitum (1969) (26)
Tumor inhibitors. LXIV. isolation and structural elucidation of novel bufadienolides, the cytotoxic principles of Bersama abyssinica (1971) (26)
Hypotensive veratrum ester alkaloids. (1961) (26)
Alkylation of a brain transport adenosinetriphosphatase at the cardiotonic steroid site by strophanthidin-3-haloacetates. (1966) (25)
TUMOR INHIBITORS PART 96, NOVEL MAYTANSINOIDS, STRUCTURAL INTERRELATIONS AND REQUIREMENTS FOR ANTILEUKEMIC ACTIVITY (1974) (25)
Hellebrigenin 3-Haloacetates: Potent Site-Directed Alkylators of Transport Adenosinetriphosphatase (1968) (25)
The isolation and structural elucidation of euparotin acetate, a novel guaianolide tumor inhibitor from Eupatorium rotundifolium. (1967) (25)
TUMOR INHIBITORS. 120. PHYLLANTHOCIN, A NOVEL BISABOLANE AGLYCONE FROM THE ANTILEUKEMIC GLYCOSIDE, PHYLLANTHOSIDE (1977) (24)
The isolation and structural elucidation of liatrin, a novel antileukemic sesquiterpene lactone from Liatris chapmanii. (1973) (24)
Tumor Inhibitors. XV. The Structure and Configuration of Cissampareine, a Novel Bisbenzylisoquinoline Alkaloid2,3 (1966) (23)
Tumor inhibitors. XXI. Active principles of Acer negundo and Cyclamen persicum. (1967) (23)
Synthesis of 5-Substituted Derivatives of 6-Methoxy-8-aminoquinoline and of 5-Chloro-6-methoxyquinoline1 (1946) (23)
Intramolecular catalysis—IV (1962) (22)
Liatrin, a novel antileukemic sesquiterpene lactone from Liatris chapmanii. (1971) (22)
Efficient intramolecular monophenol oxidative coupling (1976) (22)
Tumor inhibitors. LXII. The structures of acerotin and acerocin, novel triterpene ester aglycones from the tumor inhibitory saponins of Acer negundo. (1971) (22)
The isolation and characterization of hellebrigenin 3-acetate and hellebrigenin 3,5-diacetate, bufadienolide tumor inhibitors from Bersama abyssinica. (1968) (21)
Thalictrum alkaloids. IX. Isolation, structural elucidation, and synthesis of thalisopavine (1969) (21)
Veratrum alkaloids. XXXVII. The structure of germanitrine, a hypotensive ester alkaloid. (1959) (21)
Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase. (1973) (21)
GNIDIMACRIN AND GNIDIMACRIN 20‐PALMITATE, NOVEL MACROCYCLIC ANTILEUKEMIC DITERPENOID ESTERS FROM GNIDIA SUBCORDATA (1976) (21)
Tumor Inhibitors XIX: Desoxypodophyllotoxin, the Cytotoxic Principle of Libocedrus Decurrens (1967) (20)
Deoxyelephantopin and its interrelation with elephantopin (1970) (20)
Intramolecular Catalysis. IX.1 Intramolecular General Base-General Acid Catalysis of Ester Solvolysis2,3 (1966) (19)
Veratrum Alkaloids. XXIX.1 The Structures of Germitrine, Neogermitrine and Several Related Hypotensive Ester Alkaloids2,3 (1959) (19)
Tumor inhibitors. XXXV. Myrsine saponin, the active principle of Myrsine africana L. (1969) (19)
A convenient separation of alkaloid mixtures by partition chromatography, using an indicator in the stationary phase. (1962) (19)
The isolation and structural elucidation of a novel steroidal tumor inhibitor from Acnistus arborescens. (1965) (19)
Isolation and Characterization of Cardiotonic Steroids from the Bulb of Urginea altissima BAKER (1979) (18)
Veratrum Alkaloids. XXXVIII.1 The Structure and Configuration of Protoverine2,3 (1960) (18)
The Synthesis and Configuratin of C-Nor-D-homotestosterone Acetate (1964) (18)
New macrocyclic trichothecenes from Baccharis megapotamica. (1987) (18)
Tumor Inhibitors III. Monocrotaline, the Active Principle of Crotalaria spectabilis (1964) (18)
Buxus Alkaloids. III.1 The Structure of Cyclobuxine (1964) (18)
Zygadenus Alkaloids. III. Active Principles of Zygadenus venenosus. Veratroylzygadenine and Vanilloylzygadenine1 (1953) (18)
Total synthesis of the tumor-inhibitory alkaloid thalicarpine. (1973) (18)
Gnididione, a new furanosesquiterpene from Gnidia latifolia. (1977) (17)
Drugs from Natural Products—Plant Sources (1971) (17)
The isolation and structure elucidation of oxoxylopine, a new oxoaporphine alkaloid from Stephania abyssinica. (1970) (17)
The isolation, structural elucidation, and synthesis of solapalmitine and solapalmitenine, two novel alkaloid tumor inhibitors from Solanum tripartitum. (1967) (17)
The constitution of thalicarpine. (1967) (17)
Celacinnine, a novel macrocyclic spermidine alkaloid prototype (1974) (17)
Menispermaceae alkaloids. I. The alkaloids of Cissampelos pareira Linn. and the origin of radix pareirae brave. (1960) (17)
Drug latentiation. Synthesis and preliminary evaluation of testosterone derivatives. (1965) (16)
Microbiological transformations. IV. Hydroxylation of conessine (1963) (16)
Maytoline, maytine, and maytolidine, novel nicotinoyl sesquiterpene alkaloids from Maytenus serrata (Hochst., ex A. Rich.) R. Wilczek. (1977) (16)
The Structure, Configuration and Synthesis of Thalicarpine, a Novel Dimeric Aporphine-Benzylisoquinoline Alkaloid (1963) (16)
Buxus Alkaloids. IV.1 The Configuration of Cyclobuxine and Its Interrelation with Cycloeucalenol (1964) (16)
The Structure and Total Synthesis of Takatonine1 (1966) (16)
Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis. (1967) (16)
Eupachlorin acetate, a novel chloro-sesquiterpenoid lactone tumor inhibitor from Eupatorium rotundifolium. (1968) (16)
The isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia. (1968) (16)
Intramolecular Catalysis. VIII.1General Base-General Acid Catalysis of Ester Solvolysis2,3 (1966) (16)
Reversible thiol addition as a protecting reaction for conjugated α-methylene groups of lactones (1970) (15)
New phenolic Hasubanan alkaloids from Stephania abyssinica. (1973) (15)
Advances in the Chemistry of Tumor-Inhibitory Natural Products (1975) (15)
Mechanism of formation of spirodienone products of nonphenol oxidative coupling (1975) (15)
Veratrum Alkaloids. XXXIX.1 The Structures of Protoveratrine A and Protoveratrine B2,3 (1960) (15)
Eriolangin and eriolanin, novel antileukaemic seco-eudesmanolides from Eriophyllum lanatum (1973) (15)
Podolide, a new antileukemic norditerpene dilactone fromPodocarpus gracilior (1975) (14)
Menispermaceae alkaloids. III. Alkaloids of Stephania hernandifolia. (1961) (14)
Notes: The Synthesis of Esters of Angelic Acid (1960) (14)
Steroid hormone analogs. 3. The synthesis and stereochemistry of C-nor-D-homoprogesterone analogs. (1968) (13)
Thalictrum Alkaloids. III.1 The Structure, Configuration, and Total Synthesis of Thalicarpine, a Novel Dimeric Aporphine-Benzylisoquinoline Alkaloid2 (1964) (13)
Novel nonphenol oxidative coupling of phenethylisoquinolines (1976) (13)
Aporphine synthesis by Pschorr cyclization of aminophenols. An improved synthesis of a thalicarpine precursor. (1973) (13)
Novel oxidative photochemical aporphine synthesis. Total synthesis of corunnine and nandazurine (1973) (13)
Isolation and structural elucidation of thalidasine, a novel bis(benzylisoquinoline) alkaloid tumor inhibitor from Thalictrum dasycarpum (1967) (13)
Tumor inhibitors. XLII. Thalidasine, a novel bisbenzylisoquinoline alkaloid tumor inhibitor from Thalictrum dasycarpum. (1969) (13)
Tumor inhibitors. II. Alkaloids of Ervatamia dichotoma. Isolation, crystallization, and pharmacological properties of coronaridine. (1963) (13)
Structure-activity relationships among in vivo active germacranolides. (1978) (12)
PHOTOCHEMICAL SYNTHESIS OF PHENANTHRENES. SYNTHESIS OF ARISTOLOCHIC ACID. (1965) (12)
Veratrum alkaloids. XLI. The structure of germbundine, a hypotensive ester alkaloid. (1959) (12)
Tumor inhibitors XII. Gaillardin, A New Cytotoxic Sesquiterpene Lactone from Gaillardia pulchella (1965) (12)
Steroid Hormone Analogs. II.1 Transformations in the C-Nor-D-homosteroid Series2 (1964) (12)
Letter: Facile biomimetic synthesis of dibenzazonine and aporphine alkaloids. (1975) (11)
Schoenocaulon Alkaloids. IV. The Isomeric Cevagenine Orthoacetates1 (1955) (11)
Inhibition of phosphofructokinase by quinone methide and alpha-methylene lactone tumor inhibitors. (1970) (11)
New biogenetic-type approach to Cephalotaxus alkaloids (1977) (11)
Microbiological Transformations. II. The Aromatization of Ring a of Strophanthidin (1962) (11)
The constitution of thalicarpine (1965) (11)
NEW BIOGENETIC-TYPE APPROACH TO CEPHALOTAXUS ALKALOIDS AND THE MECHANISM OF SCHELHAMMERA-TYPE HOMOERYTHRINADIENONE FORMATION IN VITRO (1978) (11)
Veratrum Alkaloids. XXX.1The Structure and Configuration of Zygadenine2 (1959) (11)
Biomimetic synthesis of a key Erythrina alkaloid precursor (1976) (10)
Buxus Alkaloids. X.1 The Isolation and Constitution of Cyclovirobuxeine-B2 (1966) (10)
Zygadenus Alkaloids. V. Active Principles of Zygadenus venenosus. Zygacine1 (1955) (10)
The stereochemistry of gaillardin. (1969) (10)
Structure of gnidicoumarin, a novel pentacyclic dicoumarin from Gnidia lamprantha (1975) (9)
The synthesis and chemistry of elusive spirodienone alkaloid precursors (1976) (9)
MAYTOLINE, MAYTINE, AND MAYTOLIDINE, NOVEL NICOTINOYL SESQUITERPENE ALKALOIDS FROM MAYTENUS SERRATA (HOCHST., EX A. RICH.) R. WILCZEK (1977) (9)
TUMOR INHIBITORS. 122. THE MAYTANSINOIDS. ISOLATION, STRUCTURAL ELUCIDATION, N, AND CHEMICAL INTERRELATION OF NOVEL ANSA MACROLIDES (2002) (9)
Tumor inhibitors. 88. The antileukemia principles of Colchicum speciosum. (1973) (9)
Intramolecular catalysis. Facilitation of alkaline hydrolysis of alicyclic 1,2-diol monoesters☆ (1960) (9)
Buxus alkaloids. VI. The constitution of Cyclovirobuxine-D ☆ ☆☆ (1964) (9)
Schoenocaulon Alkaloids. III. The Bismuth Oxide Oxidation of Veracevine, Cevagenine and Cevine1a (1955) (9)
A note on the occurrence of 2, 6-dimethoxybenzoquinone in Rauwolfia vomitoria. (1960) (9)
General Base-General Acid-Catalysis of Ester Solvolysis (1962) (9)
Drug latentiation. 3. Labile amide derivatives of normeperidine. (1967) (9)
Total synthesis of the tumour-inhibitory alkaloids thalicarpine and hernandaline (1971) (9)
QUASSIMARIN, A NEW ANTILEUKEMIC QUASSINOID FROM QUASSIA AMARA (1977) (9)
FACILE BIOMIMETIC SYNTHESES OF DIBENZAZONINE AND APORPHINE ALKALOIDS (1975) (8)
Stereochemistry of the cucurbitacins. Crystal and molecular structure and absolute configuration of datiscoside bis-(p-iodobenzoate) dihydrate (1973) (8)
The Tiglate Ester as an Alcohol Blocking Group in Organic Synthesis1 (1962) (8)
Normaytancyprine, A Minor Antileukemic Ansa Macrolide From Putterlickia verrucosa (1982) (8)
Intramolecular Bifunctional General Base-General Acid-Catalysis of Ester Solvolysis (1963) (8)
Hydrobenzo[b]quinolizines. I. The Synthesis and Stereochemistry of Perhydrobenzo[b]quinolizines and Related Compounds1,2 (1966) (8)
Proaporphine--aporphine dimers and a bisaporphine derived from the tumor-inhibitory alkaloid thalicarpine. (1978) (8)
Veratrum Alkaloids. XLII.1 The Structures of Desacetylprotoveratrine A and Desacetylprotoveratrine B2 (1960) (8)
Buxus Alkaloids. V.1The Constitution of Cyclobuxamine, a 4β-Monomethyl Cyclosteroid Alkaloid2 (1964) (8)
Steroid hormone analogs. IV. C-nor-D-homoestrone. (1968) (8)
Structure of stephavanine, a novel Hasubanan ester alkaloid (1970) (8)
Novel photochemical aporphine synthesis via spirodienone rearrangement: (±)-boldine (1976) (7)
Veratrum alkaloids. XXXII. The structures of germitetrine and some related hypotensive ester alkaloids. (1959) (7)
ANTILEUKEMIC PRINCIPLE ISOLATED FROM DAPHNE MEZEREUM (1975) (7)
The isolation and structural elucidation of novel derivatives of aristolochic acid from Aristolochia indica. (1968) (7)
VERATRUM ALKALOIDS. XLIX. THE STRUCTURES AND CONFIGURATIONS OF SABINE AND SABADINE. (1962) (7)
Buxus alkaloids. 13. A synthetic approach to the 9(10--19) abeo-pregnane system. (1967) (7)
Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether. (1965) (7)
The chemistry of 9 ,19-cyclo steroid derivatives. (1972) (7)
l-N-Norarmepavine (1962) (7)
BUXUS ALKALOIDS. 8. THE ISOLATION AND CONSTITUTION OF CYCLOPROTOBUXINE-D. (1965) (7)
Elaeodendroside A: a novel cytotoxic cardiac glycoside from Elaeodendron glaucum (1977) (7)
Buxus alkaloids. IX. The isolation and constitution of cyclobuxoxine. (1965) (7)
Acerotin and acerocin, novel triterpene ester aglycones from the tumour-inhibitory saponins of Acer negundo (1970) (6)
Elaeodendrogenin, Elaeodendroside B and C: New Cardiac Steroids from Elaeodendron glaucum (1979) (6)
VERATRUM ALKALOIDS. XXVII. THE STRUCTURE OF PROTOVERATRINE A1 (1959) (6)
The structure of heyneanine (20-hydroxycoronaridine) and its interrelation with coronaridine (1966) (6)
The structure of stephisoferuline, a new hasubanan ester alkaloid from (1970) (6)
[Studies on Veratrum alkaloids. XVIII. Chemical and pharmacological relations between Zygadenus and Veratrum alkaloids]. (1953) (6)
Veratrum alkaloids. XL. The structure of escholerine, a hypotensive ester alkaloid. (1959) (6)
ON THE CONFIGURATION OF CEVINE (1956) (6)
Novel plant-derived tumor inhibitors and their mechanisms of action. (1976) (6)
Chapter 2 Steroid Alkaloids: The Veratrum Group (1968) (6)
Veratrum alkaloids. XLIII. The structure of cevadine. (1960) (6)
SCHOENOCAULON ALKALOIDS. II. ON THE NATURE OF THE VERACEVINE1-CEVAGENINE-CEVINE ISOMERIZATIONS (1954) (6)
The Germine-Isogermine-Pseudogermine Isomerizations1 (1955) (6)
ZYGADENUS ALKALOIDS. I. VERATROYLZYGADENINE AND VANILLOYLZYGADENINE, TWO NEW HYPOTENSIVE ESTER ALKALOIDS FROM ZYGADENUS VENENOSUS (1952) (5)
Tumor inhibitors. 70. Structure-cytotoxicity relationships among N-acyltriamines related to solapalmitine. (1972) (5)
Zygadenus Alkaloids. VI.1 Active Principles of Zygadenus paniculatus2 (1955) (5)
Tumor inhibitors. IX. Synthesis of 10-nitro-1-phenanthroic acid. (1965) (5)
Veratrum alkaloids. Part LVI. Crystal structure and absolute configuration of zygacine acetonide hydriodide acetone solvate (1973) (5)
TUMOR INHIBITORS. 127. THIOL ADDITION TO CROTEPOXIDE AND DIDEACETYLCROTEPOXIDE (1978) (5)
Novel natural products with antitumor activity. (1974) (5)
VERATRUM ALKALOIDS. XXXIV. THE CONFIGURATION OF PROTOVERINE1 (1959) (5)
Thalictrum alkaloids. 8. The isolation, structural elucidation, and synthesis of dehydrothalicarpine. (1968) (5)
Buxus alkaloids. VII. The structure of buxenine-G, a new and novel steroidal alkaloid from L. (1964) (5)
Preliminary pharmacological evaluation of extracts of takini: Helicostylis tomentosa and Helicostylis pedunculata. (1973) (5)
TUMOR INHIBITORS. 119. BACCHARIN, A NOVEL POTENT ANTILEUKEMIC TRICHOTHECENE TRIEPOXIDE FROM BACCHARIS MEGAPOTAMICA (1977) (5)
Veratrum alkaloids. LI. Hypotensive-emetic relationships in the unanesthetized dog among analogs of the protoveratrines. (1962) (5)
Veratrum alkaloids. XLVI. Structure-activity relationships in a series of analogs of the protoveratrines. (1961) (5)
The Chemistry of 3,4,7-Trisubstituted Steroids (1962) (5)
TUMOR INHIBITORS. IV. APOCANNOSIDE AND CYMARIN, THE CYTOTOXIC PRINCIPLES OF APOCYNUM CANNABINUM L. (1964) (5)
The Isolation of Crystalline Hypotensive Veratrum Ester Alkaloids by Chromatography1 (1953) (4)
ZYGADENUS ALKALOIDS. II. THE OCCURRENCE OF HYPOTENSIVE GERMINE ESTERS IN ZYGADENUS VENENOSUS (1952) (4)
ZYGADENUS ALKALOIDS. VII. ON THE STRUCTURE OF ZYGADENINE (1956) (4)
The structure of buxenine-G (1966) (4)
Microbiological Transformation of Strophanthidin (1962) (4)
The Effect of Pamaquin on the Oxygen Consumption of Liver Slices (1949) (4)
Eriofertopin and 2-O-acetyleriofertopin, new tumor inhibitory germacradienolides from Eriophyllum confertiflorum☆ (1977) (4)
The stereochemistry of germacranolide sesquiterpenes (1967) (4)
Zygadenus Alkaloids. IV. Active Principles of Zygadenus venenosus. Germine Esters1 (1954) (4)
STRUCTURAL REQUIREMENTS FOR TUMOR-INHIBITORY ACTIVITY AMONG BENZYLISOQUINOLINE ALKALOIDS AND RELATED SYNTHETIC COMPOUNDS (1973) (4)
The structure and total synthesis of takatonine (1965) (4)
Biomimetic Synthesis of the Dibenzazonine Alkaloid Laurifonine (1976) (4)
A synthetic approach to the 9(10:19)abeo-pregnane system, involving carbocyclic ring cleavage during Wolff-Kishner reduction. (1965) (3)
TUMOR INHIBITORS. 111. STRUCTURE AND STEREOCHEMISTRY OF JATROPHONE, A NOVEL MACROCYCLIC DITERPENOID TUMOR INHIBITOR (1976) (3)
TUMOR INHIBITORS. 124. STRUCTURAL REQUIREMENTS FOR ANTILEUKEMIC ACTIVITY AMONG THE NATURALLY OCCURRING AND SEMISYNTHETIC MAYTANSINOIDS (1978) (3)
Intramolecular catalysis. X. Facilitation of acylation of tertiary hydroxyl groups in alicyclic 1,3-diaxial glycols. (1967) (3)
Hydrobenzo[b]quinolizines. III.1 The Synthesis and Stereochemistry of Derivatives of 3,4,11,11a-Tetrahydro-2H-benzo[b]quinolizin-1(6H)-one2 (1966) (3)
TUMOR INHIBITORS. 117. THE ISOLATION AND STRUCTURAL ELUCIDATION OF NEW POTENT T ANTILEUKEMIC DITERPENOID ESTERS FROM GNIDIA SPECIES (1977) (3)
Veratrum alkaloids. XLV. Structure-activity relationships in a series of protoverine derivatives. (1961) (3)
STRUCTURAL ELUCIDATION OF NOVEL TUMOR-INHIBITORY SESQUITERPENE LACTONES FROM EUPATORIUM CUNEIFOLIUM (1973) (3)
ON THE NATURE OF THE GERMINE-ISOGERMINE-PSEUDOGERMINE ISOMERIZATIONS (1954) (3)
Pharmacological and chemical relation between the Vetratrum alkaloids and the Zygadenus alkaloids (1952) (2)
Drug latentiation. II. Labile ether derivatives of phenolic analgesics. (1967) (2)
THE STRUCTURE OF RINGS A AND B IN GERMINE (1954) (2)
Screening data from the Cancer Chemotherapy National Service Center screening laboratories. XXXVI. Plant extracts. (1966) (2)
Veratrum alkaloids. XLIV. Structure-activity relationships in a series of synthetic hypotensive esters of protoverine. (1961) (2)
Hydrobenzo[b]quinolizines. II.1 The Synthesis and Stereochemistry of Derivatives of 1,3,4,11a-Tetrahydro-8,9-dimethoxy-2H-benzo[b]quinolizin-11(6H)-one2 (1966) (2)
Veratrum alkaloids. XXXV. The hypotensive principles of cryptenamine, a Veratrum viriae alkaloid preparation. (1959) (2)
TUMOR INHIBITORS PART 102, GNIDIDIN, GNIDITRIN, AND GNIDICIN, NOVEL POTENT ANTILEUKEMIC DITERPENOID ESTERS FROM GNIDIA LAMPRANTHA (1975) (2)
Microbiological Transformations. III.1Reduction of the Steroid C-19 Aldehyde Group2 (1963) (2)
TUMOR INHIBITORS. 3. MONOCROTALINE, THE ACTIVE PRINCIPLE OF CROTOLARIA SPECTABILIS. (1964) (2)
The isolation and structural elucidation of voacristine hydroxyindolenine (1967) (1)
Occurrence ofd-sparteine inBaptisia leucantha T. and G. (1961) (1)
Erratum. New Macrocyclic Trichothecenes from Baccharis megapotamica (1987) (1)
Changes in brain polyphosphoinositide metabolism induced by cationic amphiphilic drugs in vitro (1981) (1)
Tumor inhibitors. 33. Cytotoxic flavones from eupatorium species. (1969) (1)
New cyto toxic neolignans from aniba megaphylla (1978) (0)
TUMOR-INHIBITOREN 87. MITT. TOTALSYNTH. DES TUMORHEMMENDEN ALKALOIDS THALICARPIN (1973) (0)
E-15-2 Microbiological Transformation of Steroidal Alkaloids(Steroids) (1964) (0)
The stereochemistry of jervine and related alkaloids. (1968) (0)
Tumor inhibitors. XXV. The synthesis and evaluation of 9-nitro-1,2,3,4-tetrahydrophenanthrene-8-carboxylic acid. (1967) (0)
E-4-1 Nuclear Magnetic Resonance Spectra of Veratrum Alkaloids(Mainly physico-chemical methods) (1964) (0)
GNIDIDIONE, A NEW FURANOSESQUITERPENE FROM GNIDIA LATIFOLIA (1977) (0)
CONFORMATION AND REACTIVITY OF THE MACROCYCLIC TUMOR-INHIBITORY ALKALOID TETRANDRINE (1976) (0)
NOVEL PHOTOCHEMICAL APORPHINE SYNTHESIS VIA SPIRODIENONE REARRANGEMENT. (.+-.)-BOLDINE (1976) (0)
TUMOR-INHIBITOREN 67. UND 68. MITT. EUPACUNIN BZW. LIATRIN, NEUE ANTILEUKAEMISCHE SESQUITERPEN-LACTONE AUS EUPATORIUM CUNEIFOLIUM BZW. LIATRIS CHAPMANII (1971) (0)
STRUCTURAL REQUIREMENTS FOR BIOLOGICAL ACTIVITY AMONG ANTILEUKEMIC GLAUCARUBOLONE ESTER QUASSINOIDS (1977) (0)
ANTRAMOLECULAR OXIDATIVE COUPLING OF MONOPHENOLIC BENZYLISOQUINOLINES, QUINONOID OXOAPORPHINES (1973) (0)
TUMOR INHIBITORS PART 107, NOVEL MAYTANSINOIDS. NATURALLY OCCURRING AND SYNTHETIC ANTILEUKEMIC ESTERS OF MAYTANSINOL (1975) (0)
Additions and Corrections -The Synthesis and Configuration of C-Nor-D-homotestosterone Acetate. (1964) (0)
NOVEL NONPHENOL OXIDATIVE COUPLING (1973) (0)
Intramolecular catalysis—V: Neighboring group facilitation in the esterification of o-hydroxyphenoxyacetic acid (1962) (0)
Tumor inhibitors. 43. Solapalmitine and solapalmitenine, two novel alkaloid tumor inhibitors from Solanum tripartitium. (1969) (0)
Professor S. Morris Kupchan (2008) (0)
DIE CHEMIE DER 9BETA,19-CYCLOSTEROID-DERIVATE (1972) (0)
Novel photochemical aporphine synthesis via spiro dienone rearrangement racemic boldine (1976) (0)
7-chloro- and 7-methoxy-8-chloro-1,2,3,4-tetrahydrophenanthrene and amino carbinols derived from them. (1946) (0)
STEREOCHEMISTRY OF THE CUCURBITACINS, CRYSTAL AND MOLECULAR STRUCTURE AND ABSOLUTE CONFIGURATION OF DATISCOSIDE BIS-(P-IODOBENZOATE)DIHYDRATE (1973) (0)
NOVEL OXIDATIVE PHOTOCHEMICAL APORPHINE SYNTHESIS, TOTAL SYNTHESIS OF CORUNNINE AND NANDAZURINE (1974) (0)
TERPENOIDE TUMOR-INHIBITOREN (1970) (0)
Veratrum Alkaloids XLIII**Received November 9. 1959, from the Department of Pharmaceutical Chemistry, University of Wisconsin. Madison. (1960) (0)
Effects of the tumor inhibitor, vernolepin, and of its thioether adduct, on the activity of catechol O-methyltransferase in vitro. (1975) (0)
Correction. Reductive Elimination of Expoxides to Olefins with Zinc-Copper Couple. (1971) (0)

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University of Virginia