S. Patricia Becerra
#147,268
Most Influential Person Now
Peruvian biochemist
S. Patricia Becerra's AcademicInfluence.com Rankings
S. Patricia Becerrabiology Degrees
Biology
#11698
World Rank
#15116
Historical Rank
Biochemistry
#2469
World Rank
#2625
Historical Rank
Download Badge
Biology
S. Patricia Becerra's Degrees
- Bachelors Biochemistry National University of San Marcos
- Masters Biochemistry National University of San Marcos
- PhD Biochemistry National University of San Marcos
Why Is S. Patricia Becerra Influential?
(Suggest an Edit or Addition)According to Wikipedia, S. Patricia Becerra is a biochemist specializing in the retina. She researches protein structure and function in relation to drug development for combating blindness. Becerra is a senior investigator at the National Eye Institute.
S. Patricia Becerra's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of a Lipase-linked Cell Membrane Receptor for Pigment Epithelium-derived Factor* (2006) (285)
- Pigment Epithelium-Derived Factor Delays the Death of Photoreceptors in Mouse Models of Inherited Retinal Degenerations (1999) (204)
- Pigment Epithelium-derived Factor Behaves Like a Noninhibitory Serpin (1995) (202)
- The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential (2013) (184)
- Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. (2005) (175)
- Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript (1988) (157)
- Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon. (1985) (152)
- Pigment Epithelium‐Derived Factor Is a Survival Factor for Cerebellar Granule Cells in Culture (1995) (152)
- Mapping the Type I Collagen-binding Site on Pigment Epithelium-derived Factor (2002) (149)
- Binding of Pigment Epithelium-derived Factor (PEDF) to Retinoblastoma Cells and Cerebellar Granule Neurons (1999) (134)
- Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. (2004) (125)
- Focus on Molecules: Pigment epithelium-derived factor (PEDF). (2006) (121)
- Pigment epithelium‐derived factor promotes the survival and differentiation of developing spinal motor neurons (1999) (121)
- Pigment epithelium-derived factor is a substrate for matrix metalloproteinase type 2 and type 9: implications for downregulation in hypoxia. (2005) (117)
- Pigment Epithelium‐Derived Factor Protects Cultured Cerebellar Granule Cells Against Glutamate‐Induced Neurotoxicity (1997) (117)
- Pigment epithelium‐derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death (1998) (116)
- Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. (1998) (114)
- Identification of the Neuroprotective Molecular Region of Pigment Epithelium-Derived Factor and Its Binding Sites on Motor Neurons (2002) (109)
- Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain. (1994) (105)
- Difference in ischemic regulation of vascular endothelial growth factor and pigment epithelium--derived factor in brown norway and sprague dawley rats contributing to different susceptibilities to retinal neovascularization. (2002) (99)
- Evidence for pigment epithelium-derived factor receptors in the neural retina. (2001) (98)
- Erythropoietin--an endogenous retinal survival factor. (2002) (97)
- Overexpression of fetal human pigment epithelium-derived factor in Escherichia coli. A functionally active neurotrophic factor. (1993) (96)
- Identification of pigment epithelium-derived factor in the interphotoreceptor matrix of bovine eyes. (1995) (92)
- Gene expression of the neurotrophic pigment epithelium-derived factor in the human ciliary epithelium. Synthesis and secretion into the aqueous humor. (1996) (80)
- Structure-Function Studies on PEDF (1997) (76)
- Pigment epithelium‐derived factor (PEDF) has direct effects on the metabolism and proliferation of microglia and indirect effects on astrocytes (1997) (71)
- Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization. (2010) (71)
- Micropatterning neuronal cells on polyelectrolyte multilayers. (2004) (64)
- Pigment epithelium‐derived factor is elevated in CSF of patients with amyotrophic lateral sclerosis (2002) (62)
- Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit binding. (1991) (61)
- Proteolytic activity directed toward pigment epithelium-derived factor in vitreous of bovine eyes. Implications of proteolytic processing. (1996) (59)
- A novel imaging technique for experimental choroidal neovascularization. (2006) (59)
- Recombinant human pigment epithelium‐derived factor (PEDF): Characterization of PEDF overexpressed and secreted by eukaryotic cells (1996) (57)
- Structure-function studies on PEDF. A noninhibitory serpin with neurotrophic activity. (1997) (56)
- Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity (1994) (53)
- Pigment epithelium‐derived factor binds to cell‐surface F1‐ATP synthase (2010) (53)
- Opposing effects of pigment epithelium-derived factor on breast cancer cell versus neuronal survival: implication for brain metastasis and metastasis-induced brain damage. (2012) (51)
- Doxycycline's effect on ocular angiogenesis: an in vivo analysis. (2010) (51)
- Pigment epithelium-derived factor reduces apoptosis and pro-inflammatory cytokine gene expression in a murine model of focal retinal degeneration (2013) (49)
- Differentiation of Y79 retinoblastoma cells with pigment epithelial-derived factor and interphotoreceptor matrix wash: effects on tumorigenicity. (1994) (46)
- Pigment epithelium-derived factor receptor (PEDF-R): a plasma membrane-linked phospholipase with PEDF binding affinity. (2010) (46)
- Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery. (2005) (45)
- Doxycycline-mediated inhibition of choroidal neovascularization. (2009) (44)
- Pigment Epithelium-derived Factor (PEDF) Prevents Retinal Cell Death via PEDF Receptor (PEDF-R) (2013) (41)
- Purification and characterization of the RNase H domain of HIV‐1 reverse transcriptase expressed in recombinant Escherichia coli (1990) (40)
- Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina (2018) (39)
- Studies on the mechanism of DNA polymerase alpha. Nascent chain elongation, steady state kinetics, and the initiation phase of DNA synthesis. (1981) (39)
- Glycosaminoglycans in human retinoblastoma cells: Heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions (2003) (39)
- Sustained subconjunctival protein delivery using a thermosetting gel delivery system. (2010) (37)
- Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K. (1993) (35)
- Sequence and expression analysis of bovine pigment epithelium-derived factor. (1998) (35)
- Expression of transthyretin and retinol binding protein mRNAs and secretion of transthyretin by cultured monkey retinal pigment epithelium. (2004) (34)
- Pigment Epithelium-Derived Factor, a Protective Factor for Photoreceptors in Vivo. (2016) (34)
- Pigment Epithelium-derived Factor Binds to Hyaluronan (2008) (32)
- The applied biochemistry of PEDF and implications for tissue homeostasis (2010) (31)
- Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective (2011) (30)
- Clusterin protein diversity in the primate eye. (2000) (30)
- Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor* (2015) (29)
- A Novel Inhibitor of 5-Lipoxygenase (5-LOX) Prevents Oxidative Stress–Induced Cell Death of Retinal Pigment Epithelium (RPE) Cells (2016) (25)
- Inhibition of tumor cell surface ATP synthesis by pigment epithelium-derived factor: implications for antitumor activity. (2012) (25)
- Functional Genetic Analysis of Rhesus Cytomegalovirus: Rh01 Is an Epithelial Cell Tropism Factor (2007) (24)
- PEDF peptides promote photoreceptor survival in rd10 retina models. (2019) (23)
- Pigment epithelium-derived factor protects cone photoreceptor-derived 661W cells from light damage through Akt activation. (2014) (21)
- Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors (2021) (19)
- Identification of Pigment Epithelium-Derived Factor Protein Forms with Distinct Activities on Tumor Cell Lines (2012) (18)
- Survival Effects of Pigment Epithelium-Derived Factor Expressed by a Lentiviral Vector in Rat Cerebellar Granule Cells (2001) (18)
- Mapping of nucleic acid binding in proteolytic domains of HIV-1 reverse transcriptase. (1993) (15)
- Pigment Epithelium-derived Factor Protects Retinal Pigment Epithelial Cells Against Cytotoxicity "In Vitro". (2018) (15)
- Pigment epithelium-derived factor mediates impaired lung vascular development in neonatal hyperoxia. (2015) (14)
- Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo (2020) (11)
- PEDF deficiency increases the susceptibility of rd10 mice to retinal degeneration. (2020) (11)
- Pigment epithelium‐derived factor (PEDF) and derived peptides promote survival and differentiation of photoreceptors and induce neurite‐outgrowth in amacrine neurons (2021) (10)
- Effects of Docosahexaenoic Acid in Preventing Experimental Choroidal Neovascularization in Rodents. (2011) (10)
- Comparison of two neurotrophic serpins reveals a small fragment with cell survival activity (2017) (9)
- Pigment Epithelium-Derived Factor: Chemistry, Structure, Biology, and Applications (2012) (9)
- Dexamethasone Increases Pigment Epithelium-Derived Factor in Perfused Human Eyes (2008) (8)
- Signaling Mechanisms Involved in PEDF-Mediated Retinoprotection. (2019) (8)
- Synthesis ofAdeno-Associated VirusStructural Proteins Requires BothAlternative mRNA Splicing andAlternative Initiations froma Single Transcript (1988) (8)
- Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R) (2021) (8)
- Expression of polypeptides of human immunodeficiency virus-1 reverse transcriptase in Escherichia coli. (1993) (6)
- Anomalous electrophoretic migration of oligodeoxynucleotides with terminal -OH groups: applications for DNA exonuclease characterization. (1983) (6)
- Pigment Epithelium-derived Factor ( PEDF ) Prevents Retinal Cell Death via Pigment Epithelium-derived Factor-R ( PEDF-R ) : Identification of a Functional Ligand Binding Site * (2013) (5)
- Role of the PNPLA2 Gene in the Regulation of Oxidative Stress Damage of RPE. (2019) (5)
- Identification of pigment epithelium-derived factor receptor (PEDF-R) antibody epitopes. (2012) (5)
- Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor. (2011) (5)
- Properties of a novel oligonucleotide-releasing bidirectional DNA exonuclease from mouse myeloma. (1984) (4)
- Pigment Epithelium-Derived Factor (PEDF) in the Retina (1999) (4)
- Pigment Epithelium-Derived Factor and Angiogenesis (2008) (4)
- Delivery Systems of Retinoprotective Proteins in the Retina (2021) (4)
- Expression and purification of the HIV-1 reverse transcriptase using the baculovirus expression vector system. (1993) (3)
- Searching for Alternatively Spliced Variants of Phospholipase Domain-Containing 2 (Pnpla2), a Novel Gene in the Retina. (2013) (3)
- PEDF in the Retina (2015) (3)
- PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE (2022) (2)
- Inflammation and Noninhibitor Serpins (1997) (2)
- Cell-based assays to identify novel retinoprotective agents (2020) (1)
- Expression and production of pigment epithelium-derived factor (PEDF) and PEDF receptor variants from mammalian and bacterial cells. (2022) (1)
- PIGMENT EPITHELIUM-DERIVED FACTOR (PEDF) IN THE RETINA Protective Effect against Photoreceptor Cell Degeneration (1999) (1)
- Pigment epithelium-derived factor is an interleukin-6 antagonist in the RPE: Insight of structure-function relationships (2022) (1)
- Characterization and Localization of Pigment Epithelium-Derived Factor Binding Sites in the Bovine Retina (2001) (1)
- Dexamethasone Increases Expression of Pigment Epithelium Derived Factor (PEDF) in Perfused Human Anterior Segments from Post-Mortem Donor Eyes (2003) (1)
- Pigment Epithelium-derived Factor Inhibits Neuroretinal Apoptosis in a Murine Model of Focal Retinal Degeneration (2012) (1)
- Characterization of pigment epithelium‐derived factor receptor (PEDF‐R) using bioinformatics tools (2006) (1)
- Identification of Structural Determinants on PEDF-R Responsible for Binding PEDF (2008) (1)
- Doxycycline Effectively Inhibits Ocular Angiogenesis (2006) (0)
- Purification and characterization of the reverse transcriptase expressed in recombinant September 1990 RNase H domain of HIV-l Escherichia coli (2001) (0)
- CHAPTER 7:PEDF Peptides in Retinal Degenerations (2018) (0)
- Factor of pigmented epithelium (PEDF) characterization, genomic organization and sequence of the PEDF gene (1995) (0)
- Rat Strain Difference in Ischemic Regulation of VEGF and PEDF and in Susceptibilities to Retinal Neovascularization (2002) (0)
- Lipase involvement in the retina-protective activity of PEDF (2013) (0)
- The phospholipase activity of a pigment epithelium‐derived factor (PEDF) receptor implies mechanisms of action for cell survival (2007) (0)
- Protease Nexin-1 (PN-1): A Novel Survival Factor for Retina Cells (2016) (0)
- Mapping the Receptor-binding Site on PEDF: Implications for a Neurotrophic Role of PEDF-R (2013) (0)
- Doxycycline-Mediated Inhibition of Matrix Metalloproteinase Types 2 and 9, and Choroidal Neovascularization (2008) (0)
- PEDF and Derived Peptides Prevent Apoptosis and Promote Differentiation of Retinal Photoreceptors (2021) (0)
- Effects of two SERPINS on ARPE-19 Cells after Acute Induced-NaIO3 Damage (2017) (0)
- Effects of Omega-3-Polyunsaturated Fatty Acids in Experimental Choroidal Neovascularization (2008) (0)
- Novel therapeutic approaches for Retinitis Pigmentosa caused by mutations in Rhodopsin (2017) (0)
- Pigment Epithelium–derived Factor Is a Substrate of MMPS: Implications for Downregulation in Hypoxia (2005) (0)
- Expression and Characterization of a Phospholipase–Linked Transmembrane Protein With Affinity for Pigment Epithelium–Derived Factor (PEDF) (2006) (0)
- Ablation of Pigment Epithelium-derived Factor Receptor (PEDF-R/Pnpla2) Causes Photoreceptor Degeneration. (2023) (0)
- Identification of A Novel Inhibitor of 5‐Lipoxygenase (2015) (0)
- 2014 Reviewer Acknowledgments (2015) (0)
- Subconjuntival Delivery of Pigment Epithelium–derived Factor (PEDF) Protein to the Choroid and Retina: Clinical Implications (2004) (0)
- Mechanistic Insight into the Interaction of Pigment-epithelium Derived Factor and Its Receptor PEDF-R for Retinal Cell Survival (2009) (0)
- A phospholipase A2‐linked receptor for PEDF (2006) (0)
- PEDF and Erythropoietin Share Protective Properties: on Retinal Neuronal Precursor Cell Lines (2004) (0)
- A Novel inhibitor of Lipoxygenase: a Patatin‐like Phospholipase Domain‐containing 2 (PNPLA2) Protein (2013) (0)
- Characterization of the Pigment Epithelium-derived Factor and Collagen Interactions (2002) (0)
- Pigmented epithelial (PEDF) factor: characterization, genomic organization and sequence of the PEDF gene (1995) (0)
- originating from pigment factor Hemmug of glial proliferation (1995) (0)
- Interactions between pigment epithelium‐derived factor (PEDF) and F1/F0 ATP synthase provide insights into its antiangiogenic mechanism (2007) (0)
- Pigment Epithelium–Derived Factor (PEDF) and ATP Synthase: A Mechanism of Action for Inhibition of Angiogenesis (2006) (0)
- Pigment epithelium-derived factor engineered to increase glycosaminoglycan affinity while maintaining bioactivity. (2022) (0)
- Peptides derived from Pigmented Epithelium-derived Factor (PEDF) prevent apoptosis and promote apical localization of rhodopsin in retinal photoreceptors (2020) (0)
- Expression, purification and characterization of a membrane-bound receptor for PEDF (2016) (0)
- Neuroprotection of photoreceptors bearing the P23H mutation in Rhodopsin (2018) (0)
- Recombinant Retinal Pigment Epithelium-Derived Factor: Its Purification from Overexpressing Escherichia Coli and Survival Effect on Induced Apoptosis in Cerebellar Granule Neurons (1995) (0)
- Ex vivo and In vivo Assays for Drug Discovery and Detection of Photoreceptor Survival Factors (2022) (0)
- Pigment epithelium-derived factor (PEDF) prevents apoptosis and promotes apical localization of opsin in retina photoreceptors (2016) (0)
- Pigment epithelium‐derived factor induced CRX alterations in the mouse retina (2022) (0)
- Structure‐function relationships of pigment epithelium‐derived factor receptor (PEDF‐R): Identification of a PEDF binding region (2011) (0)
- A 34-amino acid region of PEDF protects the RPE barrier from VEGF-induced breakdown (2013) (0)
- Gelatinase‐mediated proteolysis of pigment epithelium‐derived factor (PEDF) is pH dependent (2007) (0)
- Analyses of Patatin‐like Phospholipase Domain‐containing 2 (PNPLA2) Transcripts: Discrepancies between Expressed Sequence Tag (EST) and Experimental Data (2013) (0)
- Distinct Biological Properties of Biochemically Distinct PEDF Protein Versions on Tumor Cells (2010) (0)
- Study of the neuroprotective effects of BDNF, bFGF, CNTF or several doses of PEDF in a focal Light-emission-diode (LED) - induced phototoxicity model in adult albino mice (2016) (0)
- Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina (2018) (0)
This paper list is powered by the following services:
Other Resources About S. Patricia Becerra
What Schools Are Affiliated With S. Patricia Becerra?
S. Patricia Becerra is affiliated with the following schools:
