Sidney R. Kushner
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Sidney R. Kushnerbiology Degrees
Biology
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#15195
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Molecular Biology
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Biochemistry
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#2105
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Biology
Sidney R. Kushner's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Chemistry University of California, Berkeley
Why Is Sidney R. Kushner Influential?
(Suggest an Edit or Addition)Sidney R. Kushner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli. (1991) (1218)
- New method for generating deletions and gene replacements in Escherichia coli (1989) (710)
- Polynucleotide phosphorylase and ribonuclease II are required for cell viability and mRNA turnover in Escherichia coli K-12. (1986) (421)
- Genetic recombination in Escherichia coli: the role of exonuclease I. (1971) (316)
- Efficient transformation of Neurospora crassa by utilizing hybrid plasmid DNA. (1979) (303)
- Escherichia coli peptide methionine sulfoxide reductase gene: regulation of expression and role in protecting against oxidative damage (1995) (295)
- Identification of a novel regulatory protein (CsrD) that targets the global regulatory RNAs CsrB and CsrC for degradation by RNase E. (2006) (272)
- Polynucleotide phosphorylase functions both as a 3′ → 5′ exonuclease and a poly(A) polymerase in Escherichia coli (2000) (242)
- RNA methylation under heat shock control. (2000) (241)
- Polyadenylylation helps regulate mRNA decay in Escherichia coli. (1995) (238)
- mRNA Decay in Escherichia coli Comes of Age (2002) (235)
- The Sm‐like protein Hfq regulates polyadenylation dependent mRNA decay in Escherichia coli (2004) (230)
- Stabilization of discrete mRNA breakdown products in ams pnp rnb multiple mutants of Escherichia coli K-12 (1988) (215)
- The Ams (altered mRNA stability) protein and ribonuclease E are encoded by the same structural gene of Escherichia coli. (1991) (201)
- Initiation of tRNA maturation by RNase E is essential for cell viability in E. coli. (2002) (200)
- Involvement of helicase II (uvrD gene product) and DNA polymerase I in excision mediated by the uvrABC protein complex. (1985) (182)
- Induction of a growth‐phase‐dependent promoter triggers transcription of bolA, an Escherichia coli morphogene. (1989) (167)
- Indirect suppression of recB and recC mutations by exonuclease I deficiency. (1972) (145)
- Analysis of the function of Escherichia coli poly(A) polymerase I in RNA metabolism (1999) (143)
- Analysis of mRNA decay and rRNA processing in Escherichia coli in the absence of RNase E‐based degradosome assembly (2000) (137)
- Analysis of mRNA decay and rRNA processing in Escherichia coli multiple mutants carrying a deletion in RNase III (1993) (127)
- Recombinant levels of Escherichia coli K-12 mutants deficient in various replication, recombination, or repair genes (1978) (123)
- Identification, cloning, and expression of bolA, an ftsZ-dependent morphogene of Escherichia coli (1988) (123)
- Genomic analysis in Escherichia coli demonstrates differential roles for polynucleotide phosphorylase and RNase II in mRNA abundance and decay (2003) (123)
- RNAsnap™: a rapid, quantitative and inexpensive, method for isolating total RNA from bacteria (2012) (121)
- Enzymatic repair of DNA. 3. Properties of the UV-endonuclease and UV-exonuclease. (1971) (119)
- Analysis of Escherichia coli RNase E and RNase III activity in vivo using tiling microarrays (2010) (115)
- The majority of Escherichia coli mRNAs undergo post-transcriptional modification in exponentially growing cells (2006) (103)
- Genetic analysis of mutations indirectly suppressing recB and recC mutations. (1972) (102)
- mRNA Decay in Prokaryotes and Eukaryotes: Different Approaches to a Similar Problem (2004) (100)
- Amplification and purification of plasmid-encoded thioredoxin from Escherichia coli K12. (1984) (96)
- Polynucleotide phosphorylase, RNase II and RNase E play different roles in the in vivo modulation of polyadenylation in Escherichia coli (2000) (92)
- Regulation of mRNA Decay in Bacteria. (2016) (91)
- Expression in Escherichia coli K-12 of the structural gene for catabolic dehydroquinase of Neurospora crassa. (1977) (89)
- Isolation of exonuclease VIII: the enzyme associated with sbcA indirect suppressor. (1974) (88)
- In Vivo Studies of Temperature-Sensitive recB and recC Mutants (1974) (83)
- Identification and characterization of recombinant plasmids carrying the complete qa gene cluster from Neurospora crassa including the qa-1+ regulatory gene. (1981) (80)
- DNA repair in Escherichia coli: identification of the uvrD gene product. (1982) (79)
- Bacterial/archaeal/organellar polyadenylation (2011) (79)
- The role of the ‘gearbox’ in the transcription of essential genes (1991) (78)
- Enzymatic repair of DNA, 1. Purification of two enzymes involved in the excision of thymine dimers from ultraviolet-irradiated DNA. (1969) (76)
- Analysis of genetic recombination between two partially deleted lactose operons of Escherichia coli K-12 (1977) (75)
- RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E (2003) (75)
- RNase Z in Escherichia coli plays a significant role in mRNA decay (2006) (74)
- Construction and analysis of deletions in the structural gene (uvrD) for DNA helicase II of Escherichia coli (1991) (73)
- Biochemical and physical characterization of exonuclease V from Escherichia coli. Comparison of the catalytic activities of the RecBC and RecBCD enzymes. (1990) (66)
- Chloroplast ribosomal RNA genes in Euglena gracilis exist as three clustered tandem repeats (1978) (65)
- Polynucleotide phosphorylase functions both as a 3' right-arrow 5' exonuclease and a poly(A) polymerase in Escherichia coli. (2000) (63)
- Enzymatic repair of deoxyribonucleic acid. IV. Mechanism of photoproduct excision. (1971) (60)
- Development of an in vitro mRNA decay system for Escherichia coli: poly(A) polymerase I is necessary to trigger degradation. (1996) (55)
- Analysis of the altered mRNA stability (ams) gene from Escherichia coli. Nucleotide sequence, transcriptional analysis, and homology of its product to MRP3, a mitochondrial ribosomal protein from Neurospora crassa. (1991) (54)
- Physical and biochemical characterization of cloned sbcB and xonA mutations from Escherichia coli K-12 (1988) (53)
- Ribonuclease P processes polycistronic tRNA transcripts in Escherichia coli independent of ribonuclease E (2007) (52)
- Physical and biochemical analysis of the cloned recB and recC genes of Escherichia coli K-12 (1984) (52)
- Polyadenylation helps regulate functional tRNA levels in Escherichia coli (2012) (52)
- Exonucleases I, III, and V are required for stability of ColE1-related plasmids in Escherichia coli (1984) (51)
- Amplification in Escherichia coli of enzymes involved in genetic recombination: construction of hybrid ColE1 plasmids carrying the structural gene for exonuclease I. (1976) (50)
- Rho-independent transcription terminators inhibit RNase P processing of the secG leuU and metT tRNA polycistronic transcripts in Escherichia coli (2007) (50)
- Amplification of ribonuclease II (rnb) activity in Escherichia coli K-12. (1983) (50)
- Genetic organization and transcriptional regulation in the qa gene cluster of Neurospora crassa. (1981) (48)
- De novo computational prediction of non-coding RNA genes in prokaryotic genomes (2009) (47)
- Processing of the Escherichia coli leuX tRNA transcript, encoding tRNALeu5, requires either the 3′→5′ exoribonuclease polynucleotide phosphorylase or RNase P to remove the Rho-independent transcription terminator (2009) (47)
- UVRD, UVRE AND RECL REPRESENT A SINGLE GENE (1978) (44)
- RNase E levels in Escherichia coli are controlled by a complex regulatory system that involves transcription of the rne gene from three promoters (2002) (43)
- The umpA gene of Escherichia coli encodes phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (lgt) and regulates thymidylate synthase levels through translational coupling (1995) (43)
- Identification of a second poly(A) polymerase in Escherichia coli. (1994) (40)
- Transcription of the uvrD gene of Escherichia coli is controlled by the lexA repressor and by attenuation. (1983) (39)
- Polyadenylation of Escherichia coli transcripts plays an integral role in regulating intracellular levels of polynucleotide phosphorylase and RNase E (2002) (37)
- Identification of endonucleolytic cleavage sites involved in decay of Escherichia coli trxA mRNA (1993) (36)
- Residual polyadenylation in poly(A) polymerase I (pcnB ) mutants of Escherichia coli does not result from the activity encoded by the f310 gene (1999) (36)
- Enzymes involved in the early stages of repair of ultraviolet-irradiated DNA. (1968) (36)
- Differential Thermolability of Exonuclease and Endonuclease Activities of the recBC Nuclease Isolated from Thermosensitive recB and recC Mutants (1974) (36)
- Enzymes Involved in Posttranscriptional RNA Metabolism in Gram-Negative Bacteria. (2018) (33)
- The Escherichia coli mrsC Gene Is Required for Cell Growth and mRNA Decay (1998) (32)
- Nucleotide sequence of the thioredoxin gene fromEscherichia coli (1984) (32)
- Single amino acid changes in the predicted RNase H domain of Escherichia coli RNase G lead to complementation of RNase E deletion mutants. (2010) (32)
- Increased expression of a eukaryotic gene in Escherichia coli through stabilization of its messenger RNA. (1979) (31)
- Deregulation of poly(A) polymerase I in Escherichia coli inhibits protein synthesis and leads to cell death (2012) (31)
- Transcript mapping using [35S]DNA probes, trichloroacetate solvent and dideoxy sequencing ladders: a rapid method for identification of transcriptional start points. (1988) (30)
- Cloning of the altered mRNA stability (ams) gene of Escherichia coli K-12 (1989) (30)
- Genetic and physical analysis of the thioredoxin (trxA) gene of Escherichia coli K-12. (1984) (28)
- Analysis of RNA decay, processing, and polyadenylation in Escherichia coli and other prokaryotes. (2008) (27)
- Isolation and characterization of a new temperature-sensitive polynucleotide phosphorylase mutation in Escherichia coli K-12. (1990) (26)
- Transcription and translation in E. coli of hybrid plasmids containing the catabolic dehydroquinase gene from Neurospora crassa. (1978) (26)
- Escherichia coli mrsC Is an Allele ofhflB, Encoding a Membrane-Associated ATPase and Protease That Is Required for mRNA Decay (1998) (25)
- Physical characterization of the cloned protease III gene from Escherichia coli K-12 (1985) (25)
- Conditionally lethal ribosomal protein mutants: characterization of a locus required for modification of 50S subunit proteins. (1977) (25)
- Processing of the seven valine tRNAs in Escherichia coli involves novel features of RNase P (2014) (25)
- Identification and Characterization ofEscherichia coli DNA Helicase II Mutants That Exhibit Increased Unwinding Efficiency (1998) (24)
- The Response Regulator SprE (RssB) Modulates Polyadenylation and mRNA Stability in Escherichia coli (2009) (23)
- Endonucleolytic cleavages by RNase E generate the mature 3′ termini of the three proline tRNAs in Escherichia coli (2016) (23)
- Role of the heat shock response in stability of mRNA in Escherichia coli K-12 (1992) (22)
- Characterization of DNA helicase II from a uvrD252 mutant of Escherichia coli (1993) (22)
- The simple repeat poly(dT-dG).poly(dC-dA) common to eukaryotes is absent from eubacteria and archaebacteria and rare in protozoans. (1986) (22)
- In vivo role of the UV-endonuclease from Micrococcus luteus in the repair of DNA. (1971) (22)
- Identification and genetic mapping of the structural gene for an essential Escherichia coli membrane protein (1989) (21)
- Intragenic suppressors of temperature-sensitive rne mutations lead to the dissociation of RNase E activity on mRNA and tRNA substrates in Escherichia coli (2008) (21)
- Cloning and physical analysis of the pyrF gene (coding for orotidine-5'-phosphate decarboxylase) from Escherichia coli K-12. (1983) (21)
- Analysis of the in vivo decay of the Escherichia coli dicistronic pyrF-orfF transcript: evidence for multiple degradation pathways. (1997) (20)
- Purification and characterization of orotidine-5'-phosphate decarboxylase from Escherichia coli K-12 (1983) (20)
- Amplification and purification of exonuclease I from Escherichia coli K12. (1983) (18)
- Analysis of the regulatory region of the protease III (ptr) gene of Escherichia coli K-12. (1987) (17)
- Determination of the nucleotide sequence for the exonuclease I structural gene (sbcB) of Escherichia coli K12. (1987) (16)
- RNase E‐based degradosome modulates polyadenylation of mRNAs after Rho‐independent transcription terminators in Escherichia coli (2016) (16)
- Cloning the quinic acid (aq) gene cluster from Neurospora crassa: identification of recombinant plasmids containing both qa-2+ and qa-3+. (1981) (16)
- Expression of the HIS3 gene of Saccharomyces cerevisiae in polynucleotide phosphorylase-deficient strains of Escherichia coli K-12. (1980) (15)
- Generation of pre-tRNAs from polycistronic operons is the essential function of RNase P in Escherichia coli (2020) (15)
- Purification and characterization of exonuclease V from Escherichia coli K-12. (1984) (14)
- Conserved motifs II to VI of DNA helicase II from Escherichia coli are all required for biological activity (1997) (13)
- Isolation of plasmids carrying either the uvrC or uvrC uvrA and ssb genes of Escherichia coli K-12. (1980) (12)
- Generation of a detailed physical and genetic map of the ilv-metE-udp region of the Escherichia coli chromosome. (1988) (12)
- The cloning and analysis of the aroD gene of E. coli K-12. (1981) (11)
- New Insights into the Relationship between tRNA Processing and Polyadenylation in Escherichia coli. (2019) (11)
- Inactivation of RNase P in Escherichia coli significantly changes post‐transcriptional RNA metabolism (2021) (10)
- Isolation of Exonuclease VIII : The Enzyme Associated with the sbcA Indirect Suppressor ( genetic recombination / Escherichia coli / recB / exonuclease V ) (9)
- Identification and characterization of recombinant plasmids carrying the complete qa gene cluster from Neurospora crassa including the qa-l+ regulatory gene (9)
- Polyadenylation in E. coli: a 20 year odyssey (2015) (8)
- Expression of the structural gene for catabolic dehydroquinase of Neurospora crassa in Escherichia coli K12. (1977) (8)
- In vivo analysis of polyadenylation in prokaryotes. (2014) (8)
- The rph-1-Encoded Truncated RNase PH Protein Inhibits RNase P Maturation of Pre-tRNAs with Short Leader Sequences in the Absence of RppH (2017) (7)
- Messenger RNA Decay. (2007) (7)
- Analysis of post-transcriptional RNA metabolism in prokaryotes. (2019) (6)
- A proposal for a uniform nomenclature for the genetics of bacterial protein synthesis (1976) (5)
- Physical and genetic characterization of the cloned sbcB (exonuclease I) region of the Escherichia coli genome (1983) (5)
- Construction andAnalysis ofDeletions intheStructural Gene (uvrD) forDNA Helicase IIofEscherichia coli (1991) (4)
- CLONING: a microcomputer program for cloning simulations. (1988) (4)
- ENZYMATIC MECHANISMS FOR THE REPAIR OF UV-IRRADIATED DNA. (1971) (4)
- Enzymes Involved in Post-transcriptional RNA Metabolism in Gram-negative bacteria (2018) (3)
- [15] The UV-endonuclease from Micrococcus luteus (1971) (3)
- Isolation of the Enzyme Associated with the sbcA Indirect Suppressor (1974) (3)
- Extracellular release of protease III (ptr) by Escherichia coli K12. (1991) (2)
- mRNA Decay and Processing (2005) (2)
- Pre-tRNA and Pre-rRNA Processing in Bacteria (2004) (2)
- Comparison of the catalytic properties or the RecBC and RecBCD enzymes of Escherichia coli (1987) (2)
- Instructions for the CLONING program. (1988) (2)
- The C nucleotide at the mature 5′ end of the Escherichia coli proline tRNAs is required for the RNase E cleavage specificity at the 3′ terminus as well as functionality (2022) (1)
- Maturation of the E. coli Glu2, Ile1, and Ala1B tRNAs utilizes a complex processing pathway (2022) (1)
- Physical andBiochemical Characterization ofCloned sbcBandxonA Mutations fromEscherichia coli K-12 (1988) (1)
- FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE, MERCURY DERIVATIVE (2000) (1)
- Enzymes Involved in Posttranscriptional RNA Metabolism in Gram-Negative Bacteria (2018) (1)
- Processing of the alaW alaX operon encoding the Ala2 tRNAs in Escherichia coli requires both RNase E and RNase P (2022) (1)
- Analysis of temperature-sensitive recB and recC mutations. (1975) (1)
- Regulation of mRNA decay in E. coli (2021) (1)
- Cloning of the Altered mRNA (0)
- Poly(A) Tails (2013) (0)
- Cloning oftheAltered mRNA Stability (ams) Gene ofEscherichia coli K-12 (1989) (0)
- Spontaneous induction of colicin E1 in Escherichia coli strains deficient in both exonucleases I and V (1985) (0)
- Spontaneous Induction of Colicin El in Escherichia coli (0)
- Nucleotide sequence of the thioredoxin gene (1984) (0)
- The Development and Utilization of Recombinant DNA Technology (1978) (0)
- Immunochemical and biochemical analysis of the subunit composition of escherichia coli exonuclease v (1986) (0)
- Extracellular release of protease I11 @h) by Escherichia coli K12 (1991) (0)
- Constitutive expression in Escherichia coli of the Neurospora crassa structural gene encoding the inducible enzyme catabolic dehydroquinase (1979) (0)
- Transcription of ribosomal protein genes carried on F′ plasmids ofEscherichia coli (1977) (0)
- INSTABILITY OF HIGHER PLANT CHROMOSOMAL DNA MOLECULARLY CLONED IN E. COLI VIA RECOMBINANT PLASMIDS (1979) (0)
- Messenger RNA in Prokaryotes (2014) (0)
- Nucleic Acids Research (2003) (0)
- Dna Helicase-Ii(Uvrd) and the Rep Helicase Are Required for Escherichia-Coli Dna-Replication (1985) (0)
- rnb Multiple Mutants of Escherichia coli K-12 (0)
- FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE (2000) (0)
- Enzymatic excision of thymine dimers from UV-irradiated DNA (1973) (0)
- Transposable DNA Elements (1978) (0)
- This work 30 Derivative of A 2001 Derivative of A 2001 Derivative of EMBL 4 Derivative of X 2001 Derivative of X EMBL 4 Derivative of X 2001 Kmr Tcr lacot ' rop (0)
- Spontaneous Induction ofColicin ElinEscherichia coli Strains Deficient inBothExonucleases IandV (1985) (0)
- Genetics for Pros and Amateurs (1985) (0)
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