Stefan R. Nahorski

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Stefan R. Nahorski

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#839

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Biology

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Bachelors Biology University of Oxford

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Stefan R. Nahorski's Published Works

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Published Works

Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation (1984) (505)
Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices. (1985) (476)
Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells. (1995) (442)
Neuronal Ca2+ stores: activation and function (1995) (310)
Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences. (1991) (214)
5-Hydroxytryptamine-stimulated inositol phospholipid hydrolysis in rat cerebral cortex slices: pharmacological characterization and effects of antidepressants. (1985) (197)
Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: II. Calcium Requirement (1984) (187)
Mass measurements of inositol(1,4,5)trisphosphate in rat cerebral cortex slices using a radioreceptor assay: effects of neurotransmitters and depolarization. (1988) (186)
Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells* (1998) (179)
[3H]Rauwolscine and [3H]yohimbine binding to rat cerebral and human platelet membranes: possible heterogeneity of alpha 2-adrenoceptors. (1982) (171)
The Pharmacological Basis of Therapeutics, 8th Edition (1990) (155)
Coexistence of beta1 and beta2 adrenoceptors in mammalian lung: evidence from direct binding studies. (1978) (154)
Muscarinic-receptor-mediated changes in intracellular Ca2+ and inositol 1,4,5-trisphosphate mass in a human neuroblastoma cell line, SH-SY5Y. (1990) (145)
Molecular recognition of inositol polyphosphates by intracellular receptors and metabolic enzymes. (1989) (143)
Heterogeneity of [3H]inositol 1,4,5-trisphosphate binding sites in adrenal-cortical membranes. Characterization and validation of a radioreceptor assay. (1990) (138)
Intracellular signalling: Receptor-specific messenger oscillations (2001) (137)
Differences between the release of radiolabelled and endogenous dopamine from superfused rat brain slices: Effects of depolarizing stimuli, amphetamine and synthesis inhibition (1985) (128)
Inositol polyphosphates and neuronal calcium homeostasis (1988) (125)
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1. (1989) (123)
The muscarinic M5 receptor: a silent or emerging subtype? (2000) (123)
Non-visual GRKs: are we seeing the whole picture? (2003) (122)
Muscarinic receptor activation down-regulates the type I inositol 1,4,5-trisphosphate receptor by accelerating its degradation. (1994) (116)
Dihydropyridine calcium channel activators and antagonists influence depolarization-evoked inositol phospholipid hydrolysis in brain. (1985) (113)
Determinants of Metabotropic Glutamate Receptor-5-mediated Ca2+ and Inositol 1,4,5-Trisphosphate Oscillation Frequency (2002) (111)
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. (1998) (109)
Lack of a C-terminal Tail in the Mammalian Gonadotropin-releasing Hormone Receptor Confers Resistance to Agonist-dependent Phosphorylation and Rapid Desensitization* (1999) (109)
Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation. (1993) (107)
Acute and chronic amphetamine treatments modulate striatal dopamine receptor binding sites (1979) (105)
Desensitization of cell signalling mediated by phosphoinositidase C. (1993) (103)
Acute and chronic lithium treatments influence agonist and depolarization-stimulated inositol phospholipid hydrolysis in rat cerebral cortex. (1987) (103)
Receptors and phosphoinositide metabolism in the central nervous system. (1986) (102)
Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase. (1998) (98)
Gq/11 and Gi/o activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor‐subtype (2001) (96)
Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices. (1990) (95)
Anomalous properties of [3H]spiperone binding sites in various areas of the rat limbic system. (1979) (91)
An enzymic fluorometric micro method for determination of glycoen. (1972) (90)
Differential Effects of Lithium on Muscarinic Receptor Stimulation of Inositol Phosphates in Rat Cerebral Cortex Slices (1985) (89)
IN VIVO CHANGES OF CEREBRAL CYCLIC ADENOSINE 3′,5′‐MONOPHOSPHATE INDUCED BY BIOGENIC AMINES: ASSOCIATION WITH PHOSPHORYLASE ACTIVATION (1974) (86)
Desensitization of Gonadotropin-releasing Hormone Action in αT3-1 Cells Due to Uncoupling of Inositol 1,4,5-Trisphosphate Generation and Ca2+ Mobilization* (1996) (83)
β‐Adrenoceptor heterogeneity in guinea‐pig airways: comparison of functional and receptor labelling studies (1983) (83)
Stimulus-dependent Phosphorylation of G-protein-coupled Receptors by Casein Kinase 1α* (1997) (83)
Determination of mass changes in phosphatidylinositol 4,5-bisphosphate and evidence for agonist-stimulated metabolism of inositol 1,4,5-trisphosphate in airway smooth muscle. (1991) (79)
Heterogeneity of cerebral beta-adrenoceptor binding sites in various vertebrate species. (1978) (77)
Involvement of Intracellular Stores in the Ca2+ Responses to N‐Methyl‐D‐Aspartate and Depolarization in Cerebellar Granule Cells (1993) (75)
Mass changes of inositol(1,4,5)trisphosphate in trachealis muscle following agonist stimulation. (1989) (74)
Single-cell imaging of graded Ins(1,4,5)P3 production following G-protein-coupled-receptor activation. (2001) (73)
Rapid desensitization of muscarinic m3 receptor-stimulated polyphosphoinositide responses. (1992) (73)
Alpha 1-adrenoceptor-mediated inositol phospholipid hydrolysis in rat cerebral cortex: relationship between receptor occupancy and response and effects of denervation. (1985) (71)
Selective labelling of dopamine (D2) receptors in rat striatum by [3H]domperidone but not by [3H]spiperone. (1982) (70)
Rapid Down-regulation of the Type I Inositol 1,4,5-Trisphosphate Receptor and Desensitization of Gonadotropin-releasing Hormone-mediated Ca2+ Responses in αT3–1 Gonadotropes* (2001) (70)
Stereospecific mobilization of intracellular Ca2+ by inositol 1,4,5-triphosphate. Comparison with inositol 1,4,5-trisphosphorothioate and inositol 1,3,4-trisphosphate. (1988) (70)
Lithium Reduqes the Accumulation or Inositol Polyphosphate Second Messengers Following Cholinergic Stimulation of Cerebral Cortex Slices (1989) (68)
Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation. (2003) (68)
Lithium inhibits muscarinic-receptor-stimulated inositol tetrakisphosphate accumulation in rat cerebral cortex. (1987) (66)
Direct biochemical and neuropharmacological identification of dopamine D2-receptors in the rabbit carotid body (1984) (65)
Atypical characteristics of the beta-adrenoceptor mediating cyclic AMP generation and lipolysis in the rat adipocyte. (1985) (64)
Modulation of Gq-Protein-Coupled Inositol Trisphosphate and Ca2+ Signaling by the Membrane Potential (2006) (63)
Role of Ca2+ Feedback on Single Cell Inositol 1,4,5-Trisphosphate Oscillations Mediated by G-protein-coupled Receptors* (2003) (63)
Differential expression and regulation of ryanodine receptor and myo-inositol 1,4,5-trisphosphate receptor Ca2+ release channels in mammalian tissues and cell lines. (1997) (62)
Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism (1985) (62)
Stereospecific recognition sites for [3H]inositol(1,4,5)-triphosphate in particulate preparations of rat cerebellum. (1987) (61)
Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland (2004) (61)
Regional characterization of agonist and depolarization-induced phosphoinositide hydrolysis in rat brain. (1986) (60)
Quantitative assessment of heterogeneous 3H-spiperone binding to rat neostriatum and frontal cortex. (1980) (60)
Effects of varying the expression level of recombinant human mGlu1α receptors on the pharmacological properties of agonists and antagonists (1999) (60)
Agonist‐Evoked Ca2+ Mobilization from Stores Expressing Inositol 1,4,5‐Trisphosphate Receptors and Ryanodine Receptors in Cerebellar Granule Neurones (1996) (60)
Single Cell Analysis and Temporal Profiling of Agonist-mediated Inositol 1,4,5-Trisphosphate, Ca2+, Diacylglycerol, and Protein Kinase C Signaling using Fluorescent Biosensors* (2005) (60)
Catecholamines in the carotid body of several mammalian species: Effects of surgical and chemical sympathectomy (1982) (60)
Chronic muscarinic stimulation of SH-SY5Y neuroblastoma cells suppresses inositol 1,4,5-trisphosphate action. Parallel inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ mobilization and inositol 1,4,5-trisphosphate binding. (1991) (60)
Quantitative comparisons of muscarinic and bradykinin receptor‐mediated Ins (1,4,5)P3 accumulation and Ca2+ signalling in human neuroblastoma cells (1995) (60)
The characteristics of adrenoceptors in homogenates of human cerebral cortex labelled by (3H)-rauwolscine. (1983) (59)
Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1α metabotropic glutamate receptor (1998) (56)
Inositol 1,3,4,5-tetrakisphosphate-induced release of intracellular Ca2+ in SH-SY5Y neuroblastoma cells. (1990) (55)
Visualizing phosphoinositide signalling in single neurons gets a green light (2003) (55)
Characterization of inositol 1,4,5-trisphosphate- and inositol 1,3,4,5-tetrakisphosphate-binding sites in rat cerebellum. (1991) (55)
Divalent Cation Entry in Cultured Rat Cerebellar Granule Cells Measured Using Mn2+ Quench of Fura 2 Fluorescence (1995) (53)
Endogenous G Protein-coupled Receptor Kinase 6 Regulates M3 Muscarinic Acetylcholine Receptor Phosphorylation and Desensitization in Human SH-SY5Y Neuroblastoma Cells* (2002) (52)
Loss of beta-adrenoceptor binding sites in rat striatum following kainic acid lesions. (1979) (52)
A modulatory effect of extracellular Ca2+ on type 1α metabotropic glutamate receptor-mediated signalling (1998) (51)
α-Adrenoceptor-effector coupling: affinity states or heterogeneity of the α2-adrenoceptor? (1985) (50)
Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity (1993) (50)
Different mechanisms of Ca2+ entry induced by depolarization and muscarinic receptor stimulation in SH-SY5Y human neuroblastoma cells. (1990) (50)
G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M3 muscarinic acetylcholine receptor in human SH-SY5Y cells. (2001) (49)
Sphingosine 1-phosphate: a Ca2+ release mediator in the balance. (2002) (49)
Interactions between inositol tris- and tetrakis-phosphates. Effects on intracellular Ca2+ mobilization in SH-SY5Y cells. (1991) (49)
Increased Intracellular Calcium Stimulates 3H‐Inositol Polyphosphate Accumulation in Rat Cerebral Cortical Slices (1990) (48)
Specific Inhibition of Dopamine D‐1‐Mediated Cyclic AMP Formation by Dopamine D‐2, Muscarinic Cholinergic, and Opiate Receptor Stimulation in Rat Striatal Slices (1986) (48)
Homogeneity of beta 2-adrenoceptors on rat erythrocytes and reticulocytes. A comparison with heterogeneous rat lung beta-adrenoceptors. (1981) (48)
Histamine H2 receptors and cyclic AMP in brain. (1974) (47)
Imaging of Muscarinic Acetylcholine Receptor Signaling in Hippocampal Neurons: Evidence for Phosphorylation-Dependent and -Independent Regulation by G-Protein-Coupled Receptor Kinases (2004) (47)
Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation. (1996) (47)
Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant m1 muscarinic receptors. (1994) (47)
Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization. (1998) (46)
Differential effects of selective and non-selective neuroleptics on intracellular and extracellular cyclic AMP accumulation in rat striatal slices (1985) (46)
Characteristics of albumin binding to opossum kidney cells and identification of potential receptors (1997) (46)
Potassium depolarisation markedly enhances muscarinic receptor stimulated inositol tetrakisphosphate accumulation in rat cerebral cortical slices. (1986) (46)
Formation of inositol polyphosphates in airway smooth muscle after muscarinic receptor stimulation. (1990) (46)
A comparative study of [3H] haloperidol and [3H] spiroperidol binding to receptors on rat cerebral membranes (1978) (44)
Accumulation of inositol polyphosphate isomers in agonist-stimulated cerebral-cortex slices. Comparison with metabolic profiles in cell-free preparations. (1989) (44)
Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells. (1995) (44)
IN VIVO EFFECTS OF AMPHETAMINE ON METABOLITES AND METABOLIC RATE IN BRAIN (1973) (43)
Elevation of cytosolic calcium by cholinoceptor agonists in SH‐SY5Y human neuroblastoma cells: estimation of the contribution of voltage‐dependent currents (1992) (43)
Modulatory effects of NMDA on phosphoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R‐ACPD in neonatal rat cerebral cortex (1994) (43)
Specificity of g protein-coupled receptor kinase 6-mediated phosphorylation and regulation of single-cell m3 muscarinic acetylcholine receptor signaling. (2003) (43)
Cerebral glycogenolysis and stimulation of β-adrenoreceptors and histamine H2 receptors (1975) (42)
Identification and significance of beta-adrenoceptor subtypes (1981) (42)
Characterization of agonist-stimulated incorporation of myo-[3H]inositol into inositol phospholipids and [3H]inositol phosphate formation in tracheal smooth muscle. (1989) (42)
2-Hydroxyethyl-alpha-D-glucopyranoside-2,3',4'-trisphosphate, a novel, metabolically resistant, adenophostin A and myo-inositol-1,4,5-trisphosphate analogue, potently interacts with the myo-inositol-1,4,5-trisphosphate receptor. (1995) (41)
Cell type-specific differences in the coupling of recombinant mGlu1α receptors to endogenous G protein sub-populations (2001) (41)
Catecholamine receptors (1979) (40)
Depolarization and Agonist‐Stimulated Changes in Inositol 1,4,5‐Trisphosphate and Inositol 1,3,4,5‐Tetrakisphosphate Mass Accumulation in Rat Cerebral Cortex (1991) (40)
Muscarinic M3 receptor coupling and regulation. (1997) (40)
Pharmacological characterization of type 1α metabotropic glutamate receptor‐stimulated [35S]‐GTPγS binding (1997) (40)
Endogenous dopamine release from rat striatal slices and its regulation by D-2 autoreceptors: effects of uptake inhibitors and synthesis inhibition. (1987) (40)
Mobilization of Inositol 1,4,5‐Trisphosphate‐Sensitive Ca2+ Stores Supports Bradykinin‐ and Muscarinic‐Evoked Release of [3H]Noradrenaline from SH‐SY5Y Cells (1995) (40)
Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities. (1994) (40)
Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of M1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 in Hippocampal Neurons* (2005) (39)
Neurotransmitter and Depolarization‐Stimulated Accumulation of Inositol 1,3,4,5‐Tetrakisphosphate Mass in Rat Cerebral Cortex Slices (1990) (39)
Synthetic phosphorothioate-containing analogues of inositol 1,4,5-trisphosphate mobilize intracellular Ca2+ stores and interact differentially with inositol 1,4,5-trisphosphate 5-phosphatase and 3-kinase. (1991) (38)
3-position modification of myo-inositol 1,4,5-trisphosphate: consequences for intracellular Ca2+ mobilisation and enzyme recognition. (1992) (38)
Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation. (1999) (38)
Identification of a Novel Receptor Kinase That Phosphorylates a Phospholipase C-linked Muscarinic Receptor (*) (1996) (37)
Myo-inositol(1,4,5)trisphosphorothioate binds to specific [3H]inositol(1,4,5)trisphosphate sites in rat cerebellum and is resistant to 5-phosphatase. (1988) (37)
Association of high affinity stereospecific binding of 3H-propranolol to cerebral membranes with β adrenoceptors (1976) (37)
Depolarisation-evoked release of acetylcholine can mediate phosphoinositide hydrolysis in slices of rat cerebral cortex (1987) (36)
Albumin endocytosis is regulated by heterotrimeric GTP-binding protein G alpha i-3 in opossum kidney cells. (1996) (36)
Identification and subclassification of rat adipocyte beta-adrenoceptors using (+/-)-[125I]cyanopindolol. (1983) (36)
Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors (1999) (36)
The role of catecholamines in the action of amphetamine and L-DOPA on cerebral energy metabolism (1975) (34)
Synaptic Activity Augments Muscarinic Acetylcholine Receptor-stimulated Inositol 1,4,5-Trisphosphate Production to Facilitate Ca2+ Release in Hippocampal Neurons* (2004) (34)
Receptor phosphorylation does not mediate cross talk between muscarinic M(3) and bradykinin B(2) receptors. (1999) (34)
Characterization of the metabotropic glutamate receptors mediating phospholipase C activation and calcium release in cerebellar granule cells: calcium‐dependence of the phospholipase C response (2001) (34)
Postnatal ontogeny of agonist and depolarization-induced phosphoinositide hydrolysis in rat cerebral cortex. (1987) (33)
Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+ release. (2001) (33)
Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastoma. (1996) (33)
Investigations of the roles of dihydropyridine and ω-conotoxin-sensitive calcium channels in mediating depolarisation-evoked endogenous dopamine release from striatal slices (1989) (33)
Inositol 1:2-cyclic,4,5-trisphosphate is only a weak agonist at inositol 1,4,5-trisphosphate receptors. (1989) (33)
Distribution and characteristics of histamine H1-receptors in guinea-pig airways iddentified by [3H]mepyramine (1982) (32)
Altered responsiveness of cerebral beta adrenoceptors assessed by adenosine cyclic 3',5'-monophosphate formation and (3H)propranolol binding. (1977) (32)
Biochemical assessment of adrenoceptor function and regulation: new directions and clinical relevance. (1982) (31)
Atypical characteristics of frog and chick erythrocyte β-adrenoceptors (1981) (31)
Heterologous desensitization of both phosphoinositide and Ca2+ signaling in SH-SY5Y neuroblastoma cells: a role for intracellular Ca2+ store depletion? (1995) (30)
Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells (2008) (30)
The adenosine 3',5'-monophosphate content of brain tissue obtained by an ultra-rapid freezing technique. (1973) (29)
Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons1 (2008) (29)
Inositol-1,3,4,5-tetrakisphosphate induces calcium mobilization via the inositol-1,4,5-trisphosphate receptor in SH-SY5Y neuroblastoma cells. (1993) (29)
Muscarinic receptors coupled to phosphoinositide hydrolysis and elevated cytosolic calcium in a human neuroblastoma cell line SK‐N‐SH (1989) (29)
Accumulation and metabolism of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in muscarinic-receptor-stimulated SH-SY5Y neuroblastoma cells. (1991) (29)
Pertussis toxin separates two muscarinic receptor-effector mechanisms in the striatum. (1985) (29)
Regulation of Muscarinic Agonist‐Induced Activation of Phosphoinositidase C in Electrically Permeabilized SH‐SY5Y Human Neuroblastoma Cells by Guanine Nucleotides (1990) (29)
Role for ionotropic and metabotropic receptors in quisqualate-stimulated inositol polyphosphate accumulation in rat cerebral cortex. (1991) (28)
Constitutive Activity and Inverse Agonism at the M2 Muscarinic Acetylcholine Receptor (2006) (28)
Lack of effect of zaprinast on methacholine‐induced contraction and inositol 1,4,5‐trisphosphate accumulation in bovine tracheal smooth muscle (1991) (28)
Molecular recognition at the myo-inositol 1,4,5-trisphosphate receptor. 3-position substituted myo-inositol 1,4,5-trisphosphate analogues reveal the binding and Ca2+ release requirements for high affinity interaction with the myo-inositol 1,4,5-trisphosphate receptor. (1994) (27)
Measurement of beta-adrenoceptor antagonists in biological fluids using a radioreceptor assay. (1978) (27)
Stimulation of cyclic adenosine 3′,5′-monophosphate in chick cerebral hemisphere slices: effects of H2 and H2 histaminergic agonists and antagonists (1977) (27)
M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells. (1991) (27)
Identification of partial agonists with low intrinsic activity at the inositol-1,4,5-trisphosphate receptor. (1993) (26)
Ca2+‐mobilising properties of synthetic fluoro‐analogues of myo‐inositol 1,4,5‐trisphosphate and their interaction with myo‐inositol 1,4,5‐trisphosphate 3‐kinase and 5‐phosphatase (1990) (26)
Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+‐ and protein kinase C‐dependent pathway (2005) (26)
Stereoselectivity of Ins(1,3,4,5)P4 recognition sites: implications for the mechanism of the Ins(1,3,4,5)P4-induced Ca2+ mobilization. (1993) (26)
Altered Expression of Gq/11α Protein Shapes mGlu1 and mGlu5 Receptor-Mediated Single Cell Inositol 1,4,5-Trisphosphate and Ca2+ Signaling (2006) (26)
Muscarinic acetylcholine receptor activation enhances hippocampal neuron excitability and potentiates synaptically evoked Ca2+ signals via phosphatidylinositol 4,5-bisphosphate depletion (2005) (26)
Stimulatory and Inhibitory Effects of N‐Methyl‐D‐Aspartate on 3H‐Inositol Polyphosphate Accumulation in Rat Cortical Slices (1991) (25)
Inhibition of N-linked glycosylation of the human type 1α metabotropic glutamate receptor by tunicamycin: effects on cell-surface receptor expression and function (1999) (25)
Fluorometric measurement of glutamine and asparagine using enzymic methods. (1971) (25)
Complex involvement of pertussis toxin-sensitive G proteins in the regulation of type 1alpha metabotropic glutamate receptor signaling in baby hamster kidney cells. (2000) (25)
Stable overexpression of the type-1 inositol 1,4,5-trisphosphate receptor in L fibroblasts: subcellular distribution and functional consequences. (1996) (24)
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle. (1988) (24)
Synthesis and biology of inositol polyphosphate analogues. (1992) (24)
Muscarinic receptors, phosphoinositide metabolism and intracellular calcium in neuronal cells (1992) (24)
Differential expression and regulation of ryanodine receptor and myo-inositol 1 , 4 , 5-trisphosphate receptor Ca 2 + release channels in mammalian tissues and cell lines (1997) (24)
Phosphorylation of a phosphoinositidase C‐linked muscarinic receptor by a novel kinase distinct from β‐adrenergic receptor kinase (1993) (23)
Role of Ca 2 Feedback on Single Cell Inositol 1 , 4 , 5-Trisphosphate Oscillations Mediated by G-protein-coupled Receptors * (2003) (23)
Lithium reduces the accumulation of inositol polyphosphate second messengers following cholinergic stimulation of cerebral cortex slices. (1989) (23)
Modulation of muscarinic cholinoceptor-stimulated inositol 1,4,5-trisphosphate accumulation by N-methyl-d-aspartate in neonatal rat cerebral cortex (1994) (23)
Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors. (1999) (22)
Differential Effects of Lithium on Muscarinic Cholinoceptor‐Stimulated CMP‐Phosphatidate Accumulation in Cerebellar Granule Cells, CHO‐M3 Cells, and SH‐SY5Y Neuroblastoma Cells (1994) (22)
Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling. (2006) (22)
Interactions of endogenous and exogenous norepinephrine with alpha 2 adrenoceptor binding sites in rat cerebral cortex. (1984) (22)
Enhanced type 1alpha metabotropic glutamate receptor-stimulated phosphoinositide signaling after pertussis toxin treatment. (1997) (21)
Transmembrane signalling, intracellular messengers and implications for drug development (1990) (21)
Release of endogenous dopamine and cholecystokinin from rat striatal slices: effects of amphetamine and dopamine antagonists (1986) (21)
Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/insensitive guanine nucleotide-binding proteins. (1995) (21)
β-Adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle (1991) (21)
alpha-Adrenoceptor-effector coupling: affinity states or heterogeneity of the alpha 2-adrenoceptor? (1985) (21)
Determination of the inositol (1,4,5) trisphosphate requirement for histamine- and substance P-induced Ca2+ mobilisation in human U373 MG astrocytoma cells. (1998) (21)
Comparative Effects of Lithium on the Phosphoinositide Cycle in Rat Cerebral Cortex, Hippocampus, and Striatum (1993) (21)
Phosphoinositide-derived second messengers and the regulation of Ca2+ in vascular smooth muscle. (1994) (21)
Is the adipocyte beta-adrenoceptor a prototype for the recently cloned atypical 'beta 3-adrenoceptor'? (1990) (20)
Disruption of phosphoinositide signalling by lithium. (1992) (20)
Muscarinic receptor subtypes: inositol phosphates and intracellular calcium. (1992) (20)
Relationship between agonist binding, phosphorylation and immunoprecipitation of the m3‐muscarinic receptor, and second messenger responses (1995) (20)
Pharmacology of intracellular signalling pathways (2006) (19)
β-Adrenergic control of motility in the rat colon. II. Proportions of β1- and β2-adrenoceptors identified with 125I-(−)pindolol binding (1986) (19)
Design of potent and selective inhibitors of myo-inositol 1,4,5-trisphosphate 5-phosphatase. (1994) (19)
Coupling of muscarinic receptors to the mobilization of intracellular Ca2+ stores in permeabilized SH-SY5Y human neuroblastoma cells. (1990) (19)
Differences between muscarinic-receptor- and Ca2(+)-induced inositol polyphosphate isomer accumulation in rat cerebral-cortex slices. (1990) (18)
Inositol tetrakisphosphate: recent developments in phosphoinositide metabolism and receptor function (1986) (18)
Synthesis, calcium mobilizing, and physicochemical properties of D-chiro-inositol 1,3,4,6-tetrakisphosphate, a novel and potent ligand at the D-myo-inositol 1,4,5-trisphosphate receptor. (1999) (18)
Heterogeneous properties of alpha 2 adrenoceptors in particulate and soluble preparations of human platelet and rat and rabbit kidney. (1986) (18)
Identification of solubilised beta 1 and beta 2 adrenoceptors in mammalian lung. (1981) (17)
Rapid accumulation and sustained turnover of inositol phosphates in cerebral-cortex slices after muscarinic-receptor stimulation. (1989) (17)
Cerebral phosphodiesterase and the dopamine receptor (1973) (17)
A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism (2006) (17)
Depression of cerebral metabolism by stimulant doses of cocaine. (1973) (17)
Assessment of Neuronal Phosphoinositide Turnover and Its Disruption by Lithium (1993) (17)
Muscarinic acetylcholine receptors linked to the inhibition of adenylate cyclase activity in membranes from the rat striatum and myocardium can be distinguished on the basis of agonist efficacy. (1988) (17)
Second-messenger responses associated with stimulation of neuronal muscarinic receptors expressed by a human neuroblastoma SH-SY5Y. (1990) (16)
(-)-[125I]pindolol binding to the human platelet beta-adrenoceptor: characterisation and agonist interactions. (1985) (16)
Lysophosphatidic Acid-induced Ca 2 1 Mobilization Requires Intracellular Sphingosine 1-Phosphate Production POTENTIAL INVOLVEMENT OF ENDOGENOUS EDG-4 RECEPTORS* (2000) (16)
Differential regulation of muscarinic M1 and M3 receptors by a putative phosphorylation domain. (1999) (16)
The validity of mitochondrial marker enzymes in rat heart. (1971) (15)
Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate (1993) (15)
Urinary 3‐methoxy‐4‐hydroxyphenylglycol production in mice and rats following intraventricular 6‐hydroxydopamine (1975) (15)
Binding of 125I-iodohydroxybenzylpindolol to cerebral membranes: association with 5-hydroxytryptamine recognition sites as well as beta-adrenoceptors. (1983) (15)
The role of the 2- and 3-hydroxyl groups of 1D-myo-inositol 1,4,5-trisphosphate in the mobilisation of calcium from permeabilised human 1321N1 astrocytoma cells. (1992) (15)
Intracellular Ca2+ Stores Regulate Muscarinic Receptor Stimulation of Phospholipase C in Cerebellar Granule Cells (2000) (15)
Tools for Cell Signaling: Synthesis of the 3-Phosphatase-Resistant 1,3,4,5-InsP4 Mimic, 1D-myo-Inositol 1,4,5-Trisphosphate 3-Phosphorothioate (1994) (14)
Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea‐pig isolated uterus (1998) (14)
Phosphoinositide metabolism in airway smooth muscle. (1990) (14)
Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices. (1992) (14)
Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. (1997) (14)
A simple enzymic method to separate [3H]inositol 1,4,5- and 1,3,4-trisphosphate isomers in tissue extracts. (1989) (14)
Synthesis from quebrachitol of 1L-chiro-inositol 2,3,5-trisphosphate, an inhibitor of the enzymes of 1D-myo-inositol 1,4,5-trisphosphate metabolism (1992) (14)
Postsynaptic alpha-adrenoceptors in the hypertensive rat: studies on vascular reactivity in vivo and receptor binding in vitro. (1983) (14)
Reassessment of the Ca 2 1 Sensing Property of a Type I Metabotropic Glutamate Receptor by Simultaneous Measurement of Inositol 1,4,5-Trisphosphate and Ca 2 1 in Single Cells* (2001) (13)
Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors. (1999) (13)
Characteristics of inositol 1,4,5-trisphosphate binding to rat cerebellar and bovine adrenal cortical membranes: evidence for the heterogeneity of binding sites. (1990) (13)
Pertussis toxin inhibits alpha 2-adrenoceptor-mediated inhibition of adenylate cyclase without affecting muscarinic regulation of [Ca2+]i or inositol phosphate generation in SH-SY5Y human neuroblastoma cells. (1990) (13)
Inositol 1,4,5‐trisphosphate‐stimulated calcium release from permeabilized cerebellar granule cells (1991) (13)
Stimulated formation of cyclic AMP in different areas of chick brain. (1976) (13)
1D-myo-inositol 1,4,5-trisphosphate and 1D-myo-inositol 1,3,4,5-tetrakisphosphate analogues modified at C-3; synthesis of 1D-3-C-(trifluoromethyl)-myo-inositol 1,4,5-trisphosphate and 1L-chiro-insitol 1,2,3,5-tetrakisphosphate from L-quebrachitol (1994) (13)
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells. (2000) (13)
Effect of kainic acid lesions on muscarinic agonist receptor subtypes in rat striatum (1981) (12)
Modulation of signalling initiated by phosphoinositidase-C-linked receptors. (1993) (12)
Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor. (1993) (12)
Is decavanadate a specific inositol 1,4,5-trisphosphate receptor antagonist? (1991) (12)
The novel Ins(1,4,5)P3 analogue 3-amino-3-deoxy-Ins(1,4,5)P3: a pH-dependent Ins(1,4,5)P3 receptor partial agonist in SH-SY5Y neuroblastoma cells. (1994) (12)
The lack of gonadotrophin-releasing hormone (GnRH) receptor desensitisation in αT3-1 cells is not due to GnRH receptor reserve or phosphatidylinositol 4,5-bis-phosphate pool size (1999) (11)
Synthetic D- and L-enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate interact differently with myo-inositol 1,4,5-trisphosphate binding proteins: identification of a potent small molecule 3-kinase inhibitor. (1992) (11)
Temperature-dependent 5-hydroxytryptamine (5-HT)-sensitive [3H]spiperone binding to rat cortical membranes: regulation by guanine nucleotide and antidepressant treatment. (1983) (11)
Studies in vivo on the effects of parathyroid hormone upon kidney cyclic adenosine 3',5'-monophosphate content using rapid tissue fixation by microwave irradiation. (1976) (11)
Total synthesis from L-quebrachitol of the D-myo-inositol 1,4,5-trisphosphate analogue, L-chiro-inositol 2,3,5-trisphosphate, a potent inositol 1,4,5-trisphosphate 5-phosphatase and 3-kinase inhibitor (1991) (11)
Developmental aspects of muscarinic-induced inositol polyphosphate accumulation in rat cerebral cortex. (1989) (11)
The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons1 (2007) (10)
Lithium-induced disruption of cell signalling in brain: evidence implicating the phosphoinositide cycle. (1992) (10)
Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain (1987) (10)
Irreversible antagonism of beta-adrenoceptors with para-amino-benzyl-carazolol provides further evidence for an atypical rat adipocyte beta-adrenoceptor. (1984) (10)
Acute regulation of the receptor-mediated phosphoinositide signal transduction pathway. (1996) (10)
Studies of the α2-adrenoceptor affinity and the α2- to α1-adrenoceptor selectivity of some substituted benzoquinolizines using receptor-binding techniques (1984) (10)
Quantal calcium release in electropermeabilized SH-SY5Y neuroblastoma cells perfused with myo-inositol 1,4,5-trisphosphate. (1996) (10)
Chemical synthesis and biological evaluation of 1 d-1,2,4,5-InsP 4 and its 3-fluorinated counterpart 1 d-3-F-1,2,4,5-InsP 4 — potent 1 d-1,4,5-InsP 3-like calcium mobilizing analogues (1995) (9)
Effect of acute and chronic amphetamine administration on beta-adrenoceptors and dopamine receptors in rat corpus striatum and limbic forebrain [proceedings]. (1978) (9)
Characterisation of human platelet adrenoceptors. (1985) (9)
Cellular Receptors for Hormones and Neurotransmitters (1981) (9)
Enhanced inducible mGlu1α receptor expression in Chinese hamster ovary cells (2001) (9)
Chronic Muscarinic Stimulation of SH-SY 5Y Neuroblastoma Cells Suppresses Inositol 1,4,5-Trisphosphate Action (1991) (9)
myo-Inositol 1,4-bisphosphate-5-phosphorothioate: chemical synthesis and biochemical properties (1988) (9)
Agonist binding to mammalian beta 1 and beta 2 adrenoceptors: modulation by guanine nucleotides and magnesium. (1983) (9)
Inositol 1,4,5-trisphosphate-independent calcium signalling by platelet-derived growth factor in the human SH-SY5Y neuroblastoma cell. (2001) (9)
Intracellular recognition sites for inositol 1,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate. (1991) (8)
Measurement of Inositol 1,4,5-Trisphosphate, Inositol 1,3,4,5-Tetrakisphosphate, and Phosphatidylinositol 4,5-Bisphosphate in Brain (1993) (8)
Inhibition of 3′,5′-nucleotide phosphodiesterase and the stimulation of cerebral cyclic AMP formation by biogenic amines in vitro and in vivo (1976) (8)
ATP and the binding of [3H]inositol 1,4,5-trisphosphate to its receptor. (1988) (8)
Synthesis of 1D-3-Deoxy-, 1D-2,3-Dideoxy-, and 1D-2,3,6-Trideoxy-myo- inositol 1,4,5-Trisphosphate from Quebrachitol, Their Binding Affinities, and Calcium Release Activity. (1993) (8)
Direct evidence of two types of beta adrenoceptor binding site in lung tissue. (1978) (8)
Drug assays in plasma by radioreceptor techniques (1983) (8)
Modulation of receptor-mediated inositol phospholipid breakdown in the brain (1991) (8)
Comparison between radiolabelled and endogenous dopamine release from rat striatal slices: effects of electrical field stimulation and regulation by D2-autoreceptors (1987) (7)
Disposition and activity of beta-adrenoceptor antagonists in the rat using an ex vivo receptor binding assay. (1980) (7)
Analysis of [3H]inositol phosphate formation and metabolism in cerebral-cortical slices. Evidence for a dual metabolism of inositol 1,4-bisphosphate. (1992) (7)
Synthesis of L-chiro-inositol 1,4,6-trisphosphorothioate, a potent and selective inhibitor of myo-inositol 1,4,5-trisphosphate 5-phosphatase (1992) (7)
Potentiation of N-methyl-D-aspartate-evoked elevation of intracellular Ca2+ concentrations by exogenous glycine in cerebellar granule cells. (1994) (7)
Characterisation of the adrenoceptor mediating changes in cyclic adenosine 3′—5′ monophosphate in chick cerebral hemispheres (2004) (7)
Pitfalls in the assessment of the specific binding of(-)[3H]-dihydroalprenolol to beta-adrenoceptors [proceedings]. (1979) (6)
Pharmacological characterization of type 1alpha metabotropic glutamate receptor-stimulated [35S]-GTPgammaS binding. (1997) (6)
Evaluation of a radioreceptor assay for beta-adrenoceptor antagonists in plasma (1980) (6)
Inositol phospholipid hydrolysis as a primary response to receptors not linked to adenylate cyclase. (1985) (6)
Synthesis of novel metabolically stable analogues of D-myo-inositol 1,4,5-trisphosphate (1996) (6)
α- and β-adrenoceptor coupling to adenylate cyclase (1982) (6)
Role of Ca 2 (cid:1) Feedback on Single Cell Inositol 1,4,5-Trisphosphate Oscillations Mediated by G-protein-coupled Receptors* (2003) (5)
Increased sensitivity of rabbit carotid body chemoreceptors to dopamine after chronic treatment with domperidone. (1984) (5)
Characteristics of chick cerebral β-adrenoceptors assessed by cyclic adenosine 3′,5′ monophosphate formation and [3H]-propranolol binding (1977) (5)
Probing the D-1,4,5-IP3/D-1,3,4,5-IP4 functional interface. Synthesis and pharmacology of novel D-3-modified myo-inositol trisphosphate analogues (1994) (5)
Complex relationship between Ins(1,4,5)P3 accumulation and Ca2+ -signalling in a human neuroblastoma reveled by cellular differentiation. (1999) (5)
Inhibition of inositol 1,4,5-trisphosphate metabolism in permeabilised SH-SY5Y human neuroblastoma cells by a phosphorothioate-containing analogue of inositol 1,4,5-trisphosphate. (1990) (5)
Proceedings: The effect of phosphodiesterase inhibitors on the stimulation of cerebral cyclic AMP formation by biogenic amines in vitro and in vivo. (1975) (5)
Measurement of Ca2+ fluxes in permeabilized cells using 45Ca2+ and fluo-3. (1995) (5)
Characterization of beta-adrenergic receptor linked to adenylate cyclase in a human cancer cell line (COLO 16). (1978) (5)
Measurement of Agonist-Stimulated [ 35 S]GTPγS Binding to Assess Total G-Protein and Gα-Subtype-Specific Activation by G-Protein-Coupled Receptors (2004) (4)
REGULATION OF CYCLIC ADENOSINE 3′, 5′‐MONOPHOSPHATE CONCENTRATION IN CHICK CEREBRAL HEMISPHERES DURING DEVELOPMENT (1976) (4)
Homologous and heterologous uncoupling of muscarinic M(3) and alpha(1B) adrenoceptors to Galpha(q/11) in SH-SY5Y human neuroblastoma cells. (2001) (4)
A comparison between muscarinic receptor occupancy, inositol 1,4,5-trisphosphate accumulation and Ca2+ mobilization in permeabilized SH-SY5Y neuroblastoma cells (1994) (4)
Effect of freezing on gamma-aminobutyric acid levels in human cerebrospinal fluid. (1981) (4)
SH-SY5Y neuroblastoma cells (2005) (4)
Atypical characteristics of frog and chick erythrocyte beta-adrenoceptors. (1981) (4)
Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells. (2001) (4)
Proceedings: Cyclic AMP in developing chick brain: changes with ischaemia and catecholamine administration. (1975) (4)
In vivo changes in the concentration of cerebral cyclic AMP, phosphorylase a and glycogen induced by biogenic amines. (1973) (4)
Distribution and characteristics of histamine H1-receptors in guinea-pig airways identified by [3H]mepyramine. (1982) (4)
Inhibition of inositol 1,4,5‐trisphosphate metabolism in permeabilised SH‐SY5Y human neuroblastoma cells by a phosphorothioate‐containing analogue of inositol 1,4,5‐trisphosphate (1990) (4)
Decavanadate interacts with inositol polyphosphate binding sites and is a competitive antagonist of the inositol 1,4,5-trisphosphate receptor (1991) (4)
Beta-adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle. (1991) (3)
Regulation and Desensitization of the Phosphoinositidase C Signalling Pathway (1996) (3)
Is the human platelet beta2 adrenoceptor coupled to adenylate cyclase? (1988) (3)
2940 – CHARACTERISTICS AND REGIONAL VARIATION OF β-ADRENOCEPTOR SUBTYPES IN RAT BRAIN (1978) (3)
Effect of temperature on muscarinic cholinoceptor-mediated phosphoinositide metabolism and tension generation in bovine tracheal smooth muscle (1994) (3)
Mobilisation of intracellular Ca2+ triggers [3H]-noradrenaline release from SH-SY5Y cells. (1994) (3)
Beta-adrenergic control of motility in the rat colon. II. Proportions of beta 1- and beta 2-adrenoceptors identified with 125I-(-)pindolol binding. (1986) (3)
Synthetic inositol polyphosphates and analogues as molecular probes for neuronal second messenger receptors (1993) (3)
Changes in extracellular calcium within the physiological range influence receptor-mediated inositol phosphate responses in brain and tracheal smooth muscle slices (1989) (3)
Pharmacological characteristics of beta-adrenoceptor binding sites in intact and sympathectomized rat spleen (1979) (3)
Characterization of stereospecific binding sites for [3H]-inositol (1,4,5)-trisphosphate in airway smooth muscle. (1989) (3)
Inositol 1,4,5-triphosphate-stimulated calcium release from permeabilized cerebellar granule cells. (1991) (3)
Attempts to Characterise Dopamine Receptor-Effector Mechanisms in the Brain (1988) (3)
Analysis of dopamine interactions with [3H]-spiperone binding sites on rat corpus striatum membranes [proceedings]. (1979) (2)
Measurement of agonist-stimulated [35S]GTPgammaS binding to assess total G-protein and Galpha-subtype-specific activation by G-protein-coupled receptors. (2004) (2)
Absence of rapid desensitization and agonist-dependent phosphorylation of the mammalian gonadotropin-releasing hormone receptor (GnRH-R) is associated with the absence of a cytoplasmic c-terminal tail (1999) (2)
Increased cerebral cyclic GMP concentration induced by muscarinic cholinergic agonists and prostaglandin F2alpha [proceedings]. (1976) (2)
Differences in [3H]inositol phosphate production between the neuronal cell line (SH-SY5Y) and cerebral cortex slices in response to agents which raise intracellular calcium (1989) (2)
Analysis of the activity and distribution of beta-adrenoceptor antagonists in the rat using an ex vivo receptor binding assay [proceedings]. (1979) (2)
Homologous and heterologous uncoupling of muscarinic M 3 and a 1B adrenoceptors to G a q/11 in SH-SY5Y human neuroblastoma cells (2001) (2)
Proceedings: Altered sensitivity of beta-adrenoceptor-mediated cyclic AMP formation in brain. (1975) (2)
Generation and metabolism of Ins(1,4,5)P3 in SH-SY5Y human neuroblastoma cells: the regulatory role of Ca2+. (1991) (2)
Detection of sustained mass increases in inositol 1,3,4,5-tetrakisphosphate in agonist-stimulated airway smooth muscle. (1991) (2)
Studies of the alpha 2-adrenoceptor affinity and the alpha 2- to alpha 1-adrenoceptor selectivity of some substituted benzoquinolizines using receptor-binding techniques. (1984) (2)
Methodological aspects of receptor research: problems in the assessment of specific and non-specific binding of 3H-dihydroalprenolol to bovine lung membranes. (1984) (1)
M2 muscarinic cholinergic receptors expressed by a human neuroblastoma SK-N-SH (1989) (1)
Behavioural supersensitivity to apomorphine following cerebral dopaminergic denervation by 6-hydroxydopamine (1975) (1)
Pharmacology of Adrenoceptors (1985) (1)
Comparison of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate binding sites in cerebellum. (1991) (1)
Pertussis toxin enhances phosphoinositide signalling in baby hamster kidney cells expressing recombinant type 1-alpha metabotropic glutamate receptors (1996) (1)
Altered sensitivity of f3-adrenoceptor-mediated cyclic AMP formation in brain (2006) (1)
Analysis of labile brain constituents using a technique for the instantaneous fixation of brain tissue in vivo. (1973) (1)
Effect of lithium on muscarinic cholinoceptor-stimulated phosphoinositide-specific phospholipase C substrate selectivity in CHO-m1 cells. (1995) (1)
Carbachol increases phosphoinositide metabolism and cytosolic free calcium in SK-N-SH human neuroblastoma cells (1989) (1)
Proceedings: Regulation of the cyclic AMP concentration in chick brain by beta-adrenoreceptors and histamine H2 receptors. (1974) (1)
Quantitation of the lithium-sensitive component of the muscarinic receptor-stimulated inositol 1,3,4,5-tetrakisphosphate response in rat cerebral cortex. (1992) (1)
Heterologous mammalian expression systems for investigating the properties of metabotropic glutamate receptors. (1999) (1)
HETEROGENEITY OF β‐ADRENORECEPTOR SUBTYPES IN THE HUMAN PLACENTA (1982) (1)
Single-Cell Analysis and Temporal Profiling of Agonist-Mediated Ins(1,4,5)P 3 , Ca 2+ , Diacylglycerol and Protein Kinase C Signaling using Fluorescent Biosensors * (2005) (1)
alpha and beta-adrenoceptor coupling to adenylate cyclase. (1982) (1)
Homogeneity of beta-adrenoceptors on rat erythrocytes [proceedings]. (1979) (1)
Endogenous Dopamine Release from Brain Slices: Comparisons with Radiolabelled Release and Regulation by Autoreceptors (1988) (1)
Role of Ca 2 + feedback on single cell Ins ( 1 , 4 , 5 ) P 3 oscillations mediated by G-protein coupled receptors (2003) (1)
The Beta-adrenergic receptors (1992) (1)
Neurochemical and behavioural evidence that dopamine D-2 receptors in striatum couple to the Ni regulatory protein and inhibition of cyclic AMP accumulation (1987) (1)
Interaction of inositol polyphosphate analogues with intracellular receptors (1992) (1)
REGULATORY MECHANISMS UNDERLYING PHOSPHOINOSITIDE SIGNALLING (1996) (0)
CHARACTERISATION OF PURINOCEPTORMEDIATED Ca2+ OSCILLATIONS IN L-FIBROBLASTS (1999) (0)
Isolation of two novel g-protein-linked receptor kinases, MRK-1 and MRK-2 that phosphorylate the m3-muscarinic receptor (1995) (0)
Stimulation of ionotropic and metabotropic L-glutamate receptors in rat cerebellar granule cell cultures activates phosphoinositide/diacyl glycerol second messenger pathways (1997) (0)
Characterisation of the muscarinic receptor kinase MRK (1997) (0)
Synthesis of Novel Metabolically Stable Analogues of D‐myo‐Inositol 1, 4,5‐Trisphosphate. (1996) (0)
Development of a radioreceptor assay for beta-adrenoceptor antagonists in plasma [proceedings]. (1978) (0)
Total Synthesis from L‐Quebrachitol of the D‐myo‐Inositol 1,4,5‐ Trisphosphate Analogue, L‐chiro‐Inositol 2,3,5‐Trisphosphate (I), a Potent Inositol 1,4,5‐Trisphosphate 5‐Phosphatase, and 3‐Kinase Inhibitor. (1992) (0)
Tools for Cell Signaling: Synthesis of the 3-Phosphatase-Resistant 1,3, 4,5-InsP4 Mimic, 1D-myo-Inositol 1,4,5-Trisphosphate 3- Phosphorothioate. (1994) (0)
Neurotransmitters and their receptors: edited by U. Z. Littauer, Y. Dudai, I. Silman, V. I. Teichberg and Z. Vogel, John Wiley & Sons, 1981. £15.00 (viii + 570 pages) ISBN 0 471 27893 9 (1982) (0)
K+ depolarization markedly enhances carbachol-stimulated inositol 1,3,4,5-tetrakisphosphate production in cerebral cortex (1987) (0)
Letter: Cerebral phosphodiesterase and the dopamine receptor. (1973) (0)
Prolonged stimulation of SH-SY5Y cells with carbachol inhibits inositol 1,4,5-trisphosphate (InsP3) binding and InsP3-induced Ca2+ mobilisation. (1991) (0)
Multi-step involvement of pertussis toxin-sensitive G proteins in the modulation of phosphoinositide hydrolysis stimulated by the type 1a metabotropic glutamate receptor (1999) (0)
Heterogeneity of beta-adrenoreceptor subtypes in the human placenta. (1982) (0)
Beta-adrenoceptor binding sites in rat spleen: pharmacological characteristics and effects of chemical sympathectomy [proceedings]. (1979) (0)
Effect of receptor expression levels on phospholipase C activation in CHO cells expressing recombinant human m3 muscarinic receptors (1995) (0)
β-Adrenoceptors: Molecular biology, biochemistry and pharmacology (progress in basic and clinical pharmacology, vol. 7) (1992) (0)
Receptors, inositol polyphosphates and intracellular Ca2+. (1990) (0)
M 2 muscarinic cholinergic receptors expressed by a human neuroblastoma SKN-SH (2009) (0)
Proceedings: In-vivo studies of parathyroid hormone action on chick kidney cyclic adenosine 3':5'-monophosphate content using rapid tissue fixation. (1976) (0)
Metabolism and intracellular receptors for inositol 1, 4, 5-trisphosphate in brain (1989) (0)
/3-Adrenergic Control of Motility in the Rat Colon. II. ProPortions of PI- and &-Adrenoceptok Identified With lz51 v( -)Pindolol Binding (1986) (0)
2-Hydroxyethyl alpha-D-glucopyranoside 2,3',4'-trisphosphate: a novel metabolically resistant adenophostin A and myo-inositol 1,4,5-trisphosphate analogue potently interacts with the myo-inositol 1,4,5-trisphosphate receptor. (1995) (0)
Agonist interactions with [3H]-spiperone binding sites on rat corpus striatum membranes [proceedings]. (1979) (0)
Proceedings: Beta-adrenoceptor development in chick brain assessed by (3H)propranolol binding. (1976) (0)
A comparative study of growth factor receptor and G-protein-coupled receptor phosphoinositide and Ca2+ signalling in SH-SY5Y neuroblastoma cells (1999) (0)
Journal of Neural Transmission, Supplementum 18, Basic Aspects of Receptor Biochemistry Edited by M. Goldstein, K. Jellinger and P. Riederer. Published by Springer-Verlag (Wien, New York), 1983, Price DM148 (1984) (0)
AGONIST BINDING TO MAMMALIAN BETA1 AND BETA2 ADREWZGTDFB: MCBIULATICN BY GUANINE NUCLFWTIDES AND MAcrNESIUM (1983) (0)
Mechanisms of Receptor Regulation. By G. Poste and S. T. Crooke. Pp. 432. (Plenum Publishing Corporation, 1986.) $59.50 + 20% outside U.S.A (1987) (0)
Inositol 1,4,5-trisphosphate perfusion of electropermeabilised SH-SY5Y neuroblastoma cells produces quantal calcium uptake and release. (1996) (0)
CHAPTER 125 – Sphingosine 1-phosphate (2003) (0)
Generation and Ca Uncoupling of Inositol 1,4,5-Trisphosphate T3-1 Cells Due to α Hormone Action in Desensitization of Gonadotropin-releasing Cell Biology and Metabolism: (2014) (0)
Inositol 1,4,5-Trisphosphate Receptor Down-Regulation (1993) (0)
a-and b-adrenoceptor coupling to adenylate cyclase (0)
Complex relationship between Ins(1,4,5)P 3 accumulation and Ca 2+ -signalling in a human neuroblastoma revealed by cellular di(cid:128)erentiation (1999) (0)
Acute and Chronic Effects of Amphetamine on Cerebral Energy Metabolism and Cyclic Nucleotides (2019) (0)
Characteristics of (-)-[3H]-dihydroalprenolol binding to beta-adrenoceptors on rat lung membranes [proceedings]. (1977) (0)
Carbachol-stimulated cAMP accumulation in CHO cells expressing recombinant M1, M3 or M5 muscarinic receptors (1995) (0)
Characteristics and altered sensitivity of cerebral beta-adrenoceptors assessed by [3H]-propranolol binding [proceedings]. (1976) (0)
Binding of [ 3 H 1-neuroleptics to dopamine receptors on rat cerebral membranes (2006) (0)
Receptor-mediated phosphoinositide metabolism in brain (1989) (0)
Proceedings: Developmental changes in the sensitivity of neurohormone-stimulated cyclic AMP formation in chick cerebral hemispheres. (1976) (0)
[Clebopride, a new orthopramide with potent and selective central antidopaminergic properties]. (1978) (0)
Analysis of the activity and distribution of 0-adrenoceptor antagonists in the rat using an ex vivo receptor binding assay (2007) (0)
Agonist induced phosphorylation of M1 muscarinic receptors (1995) (0)
Methods in Biogenic Amine Research Edited by S. Parvez T. Nagatsu I. Nagatsu and H. Parvez. Elsevier, Amsterdam, 1983. 1028 pp. US $268.00 (1984) (0)
Rapid desensitization of phosphoinositide responses following activation of muscarinic m3 receptors but not GnRH receptors in αT3-1 cells implicates a receptor dependent mechanism (1997) (0)
1D-myo-Inositol 1,4,5-Trisphosphate and 1D-myo-Inositol 1,3,4,5- Tetrakisphosphate Analogues Modified at C-3; Synthesis of 1D-3-C-( Trifluoromethyl)-myo-inositol 1,4,5-Trisphosphate and 1L-chiro- Inositol 1,2,3,5-Tetrakisphosphate from L-Quebrachitol. (1994) (0)
LPA-induced Ca2+ mobilisation in SH-SY5Y cells is independent of phosphoinositide turnover, but dependent on sphingosine kinase stimulation (1999) (0)
m3-muscarinic receptor specific antisera for use in studies of muscarinic receptor desensitisation (1993) (0)
Development of a radioreceptor assay for fl-adrenoceptor antagonists in plasma (2006) (0)
Binding of [3H]-neuroleptics to dopamine receptors on rat cerebral membranes [proceedings]. (1978) (0)
Phosphorothioate analogues of inositol phosphates (1990) (0)
Regulation of Receptor Mediated Albumin Endocytosis by Gtp-Binding Protein G i3α in ok Cells (1996) (0)
Erratum: New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor, Trends Pharmacol. Sci. 19, 467-475 (1998) (0)
Humanplatelet 132-adrenoceptors: agonist-induced internalisation anddown-regulation inintact cells (1987) (0)
Phosphoproteins in Neuronal Function (Progress in Brain Research, Vol. 69) edited by W. H. Gispen and A. Routtenberg, Elsevier, 1986. $131.00/ Dfl.295.00 (xi + 394 pages) ISBN 0 444 80781 0 (1988) (0)
EVALUATION OF MYO-INOSITOL(1,4,5)TRISPHOSPHOROTHIOATE, A NOVEL PHOSPHATASE-RESISTANT ANALOG OF MYO-INOSITOL(1,4,5)TRISPHOSPHATE (1988) (0)
1527 – 3-BUTYROPHENONE BINDING SITES AND DOPAMINE RECEPTORS (1978) (0)

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