Saak Ovsepian
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Saak Ovsepianengineering Degrees
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#204
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Biomedical Engineering
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#930
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#3481
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Saak Ovsepianbiology Degrees
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Endocrinology
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#256
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#339
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#243
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#406
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Engineering Biology
Saak Ovsepian's Degrees
- Masters Biomedical Engineering Stanford University
Why Is Saak Ovsepian Influential?
(Suggest an Edit or Addition)According to Wikipedia, Saak Victor Ovsepian is an Armenian-Irish neuroscientist best known for his research in neurobiology, neurotherapeutics and translational biosciences. He is a professor in biosciences at the University of Greenwich.
Saak Ovsepian's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- η-Secretase processing of APP inhibits neuronal activity in the hippocampus (2015) (306)
- Activation of TRPV1 Mediates Calcitonin Gene-Related Peptide Release, Which Excites Trigeminal Sensory Neurons and Is Attenuated by a Retargeted Botulinum Toxin with Anti-Nociceptive Potential (2009) (205)
- Multispectral Optoacoustic Tomography (MSOT) of Human Breast Cancer (2017) (179)
- PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation. (2015) (169)
- Endogenous acetylcholine lowers the threshold for long‐term potentiation induction in the CA1 area through muscarinic receptor activation: in vivo study (2004) (160)
- Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions (2015) (107)
- Non-invasive Measurement of Brown Fat Metabolism Based on Optoacoustic Imaging of Hemoglobin Gradients. (2018) (89)
- Neuro-exocytosis: botulinum toxins as inhibitory probes and versatile therapeutics. (2009) (76)
- Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin (2014) (68)
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (2020) (53)
- Extravesicular intraneuronal migration of internalized botulinum neurotoxins without detectable inhibition of distal neurotransmission. (2012) (50)
- Dendritic SNAREs add a new twist to the old neuron theory (2011) (47)
- Pushing the Boundaries of Neuroimaging with Optoacoustics (2017) (45)
- The leaner P/Q‐type calcium channel mutation renders cerebellar Purkinje neurons hyper‐excitable and eliminates Ca2+‐Na+ spike bursts (2007) (42)
- Optoacoustic Dermoscopy of the Human Skin: Tuning Excitation Energy for Optimal Detection Bandwidth With Fast and Deep Imaging in vivo (2017) (40)
- Long non-coding RNA PARTICLE bridges histone and DNA methylation (2017) (40)
- Distinctive role of KV1.1 subunit in the biology and functions of low threshold K(+) channels with implications for neurological disease. (2016) (40)
- Synaptic vesicle cycle and amyloid β: Biting the hand that feeds (2018) (39)
- Disruption of Myelin Leads to Ectopic Expression of KV1.1 Channels with Abnormal Conductivity of Optic Nerve Axons in a Cuprizone-Induced Model of Demyelination (2014) (37)
- Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons (2014) (33)
- Targeted delivery into motor nerve terminals of inhibitors for SNARE‐cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin (2012) (32)
- Neuronal activity and amyloid plaque pathology: an update. (2015) (29)
- Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo (2017) (29)
- Cholinergic Mechanisms in the Cerebral Cortex (2016) (29)
- Assessing hyperthermia‐induced vasodilation in human skin in vivo using optoacoustic mesoscopy (2018) (27)
- Amyloid Plaques of Alzheimer’s Disease as Hotspots of Glutamatergic Activity (2018) (25)
- Extended Near-Infrared Optoacoustic Spectrometry for Sensing Physiological Concentrations of Glucose (2018) (25)
- Innocuous full-length botulinum neurotoxin targets and promotes the expression of lentiviral vectors in central and autonomic neurons (2011) (24)
- Hybrid multispectral optoacoustic and ultrasound tomography for morphological and physiological brain imaging (2016) (24)
- High-Resolution Multispectral Optoacoustic Tomography of the Vascularization and Constitutive Hypoxemia of Cancerous Tumors1 (2016) (24)
- Hybrid optical and acoustic resolution optoacoustic endoscopy. (2016) (24)
- Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb (2014) (23)
- PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome (2017) (22)
- Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system (2013) (19)
- A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets (2013) (18)
- Wiring prior to firing: the evolutionary rise of electrical and chemical modes of synaptic transmission (2014) (17)
- Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors (2016) (17)
- The birth of the synapse (2017) (17)
- Enhanced Synaptic Inhibition Disrupts the Efferent Code of Cerebellar Purkinje Neurons in Leaner Cav2.1 Ca2+ Channel Mutant Mice (2012) (16)
- The circRNA interactome–innovative hallmarks of the intra- and extracellular radiation response (2017) (16)
- Methamphetamine and Sleep: Neurobehavioral Correlates and Molecular Mechanisms. (2021) (15)
- Differential cholinergic modulation of synaptic encoding and gain control mechanisms in rat hippocampus (2008) (15)
- Enhancement of the synchronized firing of CA1 pyramidal cells by medial septum preconditioning: Time-dependent involvement of muscarinic cholinoceptors and GABAB receptors (2006) (15)
- Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography (2019) (15)
- Improved lentiviral transduction of ALS motoneurons in vivo via dual targeting. (2013) (14)
- The dark matter of the brain (2019) (14)
- Erratum to: Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments (2015) (14)
- Therapeutic effectiveness of botulinum neurotoxin A: Potent blockade of autonomic transmission by targeted cleavage of only the pertinent SNAP-25 (2013) (13)
- Neurobiology and therapeutic applications of neurotoxins targeting transmitter release. (2019) (13)
- Endogenous antagonists of N‐methyl‐d‐aspartate receptor in schizophrenia (2020) (13)
- Brain-derived neurotropic factor (BDNF) promotes molecular polarization and differentiation of immature neuroblastoma cells into definitive neurons. (2020) (13)
- The circRNA interactome-innovative hallmarks of the intra- and extracellular radiation response. (2017) (13)
- Neurobiology, Functions, and Relevance of Excitatory Amino Acid Transporters (EAATs) to Treatment of Refractory Epilepsy (2020) (12)
- Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer's Disease (2019) (12)
- Circumventing Brain Barriers: Nanovehicles for Retroaxonal Therapeutic Delivery. (2016) (12)
- Acute and Chronic Sleep Deprivation-Related Changes in N-methyl-D-aspartate Receptor—Nitric Oxide Signalling in the Rat Cerebral Cortex with Reference to Aging and Brain Lateralization (2019) (11)
- Unpacking Pandora from Its Box: Deciphering the Molecular Basis of the SARS-CoV-2 Coronavirus (2020) (10)
- Trophic factors as potential therapies for treatment of major mental disorders (2021) (10)
- Tuberous Sclerosis (tsc2+/-) Model Eker Rats Reveals Extensive Neuronal Loss with Microglial Invasion and Vascular Remodeling Related to Brain Neoplasia (2019) (10)
- Intrinsic voltage dynamics govern the diversity of spontaneous firing profiles in basal forebrain noncholinergic neurons. (2012) (10)
- Serotonergic modulation of synaptic transmission and action potential firing in frog motoneurons (2006) (9)
- Cholinergic neurons—keeping check on amyloid β in the cerebral cortex (2013) (9)
- Advances in Optoacoustic Neurotomography of Animal Models. (2019) (9)
- PARTICLE − The RNA podium for genomic silencers (2019) (8)
- The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients (2017) (7)
- Visualizing cortical response to optogenetic stimulation and sensory inputs using multispectral handheld optoacoustic imaging (2019) (7)
- Dual effect of GABA on descending monosynaptic excitatory postsynaptic potential in frog lumbar motoneurons (2004) (6)
- Electrophysiological approaches to unravel the neurobiological basis of appetite and satiety: use of the multielectrode array as a screening strategy. (2017) (6)
- Can Arginase Inhibitors Be the Answer to Therapeutic Challenges in Alzheimer’s Disease? (2018) (6)
- Evolutionary origins of chemical synapses. (2020) (5)
- Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes (2021) (5)
- Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases (2022) (5)
- Estrogen pendulum in schizophrenia and Alzheimer’s disease: Review of therapeutic benefits and outstanding questions (2021) (5)
- Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons (2013) (4)
- The Ups and Downs of BACE1: Walking a Fine Line between Neurocognitive and Other Psychiatric Symptoms of Alzheimer’s Disease (2020) (4)
- Neurobiology and therapeutic utility of neurotoxins targeting postsynaptic mechanisms of neuromuscular transmission. (2019) (4)
- Low-Affinity Neurotrophin Receptor p75 Promotes the Transduction of Targeted Lentiviral Vectors to Cholinergic Neurons of Rat Basal Forebrain (2016) (4)
- Dendritic spine remodeling and plasticity under general anesthesia (2021) (3)
- [Participation of the GABA B receptors in presynaptic inhibition of the spinal cord descending projections fibers in the frog Rana ridibunda]. (2002) (3)
- Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism‐like neurobehavioral phenotype in a rat model (2022) (2)
- Alleviation of Trigeminal Nociception Using p75 Neurotrophin Receptor Targeted Lentiviral Interference Therapy (2018) (2)
- Optoacoustic endoscopy with optical and acoustic resolution (2017) (2)
- Enhanced Extracellular Transfer of HLA-DQ Activates CD3+ Lymphocytes towards Compromised Treg Induction in Celiac Disease (2022) (2)
- Integrated phylogeny of the human brain and pathobiology of Alzheimer’s disease: A unifying hypothesis (2021) (2)
- Expression and Localization of AβPP in SH-SY5Y Cells Depends on Differentiation State (2021) (2)
- Adult Neurogenesis in the Gut, Homeostatic Autoimmunity and Neurodegenerative Disease Biomarkers (2022) (2)
- The peculiarities of rotational friction welding of superalloy VG175 (2017) (1)
- Mainstream psychiatry reinstates therapeutic ventures of the remote past. (2021) (1)
- All-Trans Retinoic Acid Fosters the Multifarious U87MG Cell Line as a Model of Glioblastoma (2021) (1)
- From network architecture of forebrain systems to brain wide web (2015) (0)
- Forthcoming Articles (2021) (0)
- Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes (2021) (0)
- Non-invasive Measurement of Brown Fat Metabolism Based on Optoacoustic Imaging of Hemoglobin Gradients (2018) (0)
- Non-invasive measurement of brown fat metabolism based on optoacoustic 1 imaging of hemoglobin gradients . 2 3 (2017) (0)
- The birth of the synapse (2017) (0)
- [The study of the role of the GABA A and GABA B receptors in presynaptic inhibition of primary afferents of spinal cord of the frog Rana ridibunda]. (2002) (0)
- Low-Affinity Neurotrophin Receptor p75 Promotes the Transduction of Targeted Lentiviral Vectors to Cholinergic Neurons of Rat Basal Forebrain (2016) (0)
- Can Arginase Inhibitors Be the Answer to Therapeutic Challenges in Alzheimer’s Disease? (2018) (0)
- Leech Sensory Neurons Representation of Touch Location by a Population of (2015) (0)
- Detoxified tetanus toxin (TETIM) – A superb nano-carrier for retro-axonal gene delivery to motor neurons in bypass of blood brain barriers (2019) (0)
- The dark matter of the brain (2019) (0)
- PARTICLE , a Triplex-Form ing Long ncRNA , Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation Graphical Abstract Highlights (2015) (0)
- The Immunological Epigenetic Landscape of the Human Life Trajectory (2022) (0)
- PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome (2017) (0)
- Pain Relief With Interference shRNA Proves Viable (2018) (0)
- Brain-derived neurotrophic factor (BDNF) in perinatal depression: Side show or pivotal factor? (2022) (0)
- THE UTILITY OF P75NTR FOR TARGETED TRANSDUCTION OF BASAL FOREBRAIN CHOLINERGIC NEURONS (2016) (0)
- Delineating the mechanisms of synaptic transmission for the development of targeted neurotherapeutics (2021) (0)
- Front Cover: Assessing hyperthermia-induced vasodilation in human skin in vivo using optoacoustic mesoscopy (J. Biophotonics 11/2018) (2018) (0)
- Glutamate Transporters (EAAT-1–3) as a Factor in the Pathogenesis and a Potential Therapeutic Target in Epilepsy (2020) (0)
- More Than Just A Neuron: A New Trick From An Old Dog (2018) (0)
- The impact of constitutive mTORC1 hyperactivity on structural synaptic plasticity and social behaviour under standard conditions and environmental enrichment (2022) (0)
- [Intracellular recording of the frog dorsal root single fibres' responses mediated by the GABAA and 5-HT-receptors]. (2004) (0)
- Developmental effects of constitutive mTORC1 hyperactivity and environmental enrichment on structural synaptic plasticity and behaviour in a rat model of autism spectrum disorder (2022) (0)
- Cuprizone administration to mice induces widespread demyelination in several brain structures and reduces the myelin content. (2014) (0)
- WITHDRAWN: Enhanced Synaptic Inhibition Slows and Degrades the Efferent Code of Cerebellar Purkinje Neurons in CaV2.1 Channel Mutant Leaner Mice. (2010) (0)
- Molecular Biomarkers of Neuronal Injury in Epilepsy Shared with Neurodegenerative Diseases (2023) (0)
- Pharmacology of Botulinum Neurotoxins: Exploitation of Their Multifunctional Activities as Transmitter Release Inhibitors and Neuron-Targeted Delivery Vehicles (2014) (0)
- The Birth Of Synapse – A Brief History Of One Of The Most Intricate Inventions Of Life (2018) (0)
- Endogenous Modulators of NMDA Receptor Control Dendritic Field Expansion of Cortical Neurons (2022) (0)
- Title : A Defined Heteromeric KV 1 Channel Stabilizes the Intrinsic Pacemaking and Regulates the Efferent Code of Deep Cerebellar Nuclear Neurons to Thalamic Targets (2012) (0)
- Enhanced Synaptic Inhibition Disrupts the Efferent Code of Cerebellar Purkinje Neurons in Leaner Cav2.1 Ca2+ Channel Mutant Mice (2010) (0)
- Long non-coding RNA PARTICLE bridges histone and DNA methylation (2017) (0)
- Issue Information‐ToC (2019) (0)
- The Melody Of Sugar: A New Dimension In Diabetes Research (2018) (0)
- Gene therapy for chronic pain: emerging opportunities in target-rich peripheral nociceptors (2023) (0)
- When Brain Bleeds Glutamate: A New Perspective On Alzheimer’s Disease (2018) (0)
- Alleviation of Trigeminal Nociception Using p75 Neurotrophin Receptor Targeted Lentiviral Interference Therapy (2018) (0)
- Erratum to: Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments (2015) (0)
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Saak Ovsepian is affiliated with the following schools:
