Salem Chouaib

Q: What Schools Are Affiliated With Salem Chouaib

Salem Chouaib is affiliated with the following schools: University of Lausanne, Paris-Saclay University, Gulf Medical University, National University of Singapore

Salem Chouaib's AcademicInfluence.com Rankings

Salem Chouaib

Medical

#3009

World Rank

#3459

Historical Rank

Oncology

#204

World Rank

#211

Historical Rank

medical Degrees

Salem Chouaib

Biology

#11795

World Rank

#15219

Historical Rank

Immunology

#772

World Rank

#795

Historical Rank

biology Degrees

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Biology

Salem Chouaib's Degrees

PhD Immunology Université Paris Cité
Doctorate Medicine Université Paris Cité

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Salem Chouaib's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation (2014) (1370)
The host-tumor immune conflict: from immunosuppression to resistance and destruction. (1997) (385)
Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression. (1985) (293)
Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia. (2015) (269)
New insights into the role of EMT in tumor immune escape (2017) (268)
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis. (2013) (243)
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia (2013) (236)
Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer (2017) (234)
αEβ7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis (2007) (228)
Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer (2015) (226)
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression. (2011) (224)
Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts (2018) (220)
Microglia-derived TGF-β as an important regulator of glioblastoma invasion—an inhibition of TGF-β-dependent effects by shRNA against human TGF-β type II receptor (2008) (205)
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200 (2017) (180)
The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. (1984) (179)
Phosphostim-Activated γδ T Cells Kill Autologous Metastatic Renal Cell Carcinoma1 (2005) (176)
The Cooperative Induction of Hypoxia-Inducible Factor-1α and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis12 (2009) (176)
Biology and clinical applications (2004) (175)
The mechanism of inhibition of human IL 2 production. (1982) (172)
Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells. (2012) (163)
Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma. (2001) (163)
Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape (2012) (157)
A common pathway for T lymphocyte activation involving both the CD3-Ti complex and CD2 sheep erythrocyte receptor determinants. (1986) (155)
Microglia-derived TGF-beta as an important regulator of glioblastoma invasion--an inhibition of TGF-beta-dependent effects by shRNA against human TGF-beta type II receptor. (2008) (144)
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner (2017) (143)
High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy. (2004) (140)
Quantitative analysis of Th1, Th2 and TGF‐β1 cytokine expression in tumor, TIL and PBL of non‐small cell lung cancer patients (1998) (139)
Tumor-Associated Macrophages (TAMs) Form an Interconnected Cellular Supportive Network in Anaplastic Thyroid Carcinoma (2011) (135)
Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery. (2011) (135)
A point mutation in the alpha-actinin-4 gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human lung carcinoma. (2001) (135)
IL-15 enhances immune functions during HIV infection. (1997) (132)
Accumulation of the p53 protein allows recognition by human CTL of a wild-type p53 epitope presented by breast carcinomas and melanomas. (1998) (131)
Prion Protein Prevents Human Breast Carcinoma Cell Line from Tumor Necrosis Factor α-Induced Cell Death (2004) (130)
In Vitro Processing of Human Tumor Necrosis Factor-α (*) (1995) (122)
IκBα Overexpression in Human Breast Carcinoma MCF7 Cells Inhibits Nuclear Factor-κB Activation but Not Tumor Necrosis Factor-α-induced Apoptosis* (1997) (122)
Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. (1994) (121)
Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges (2019) (118)
Alteration of the Sphingomyelin/Ceramide Pathway Is Associated with Resistance of Human Breast Carcinoma MCF7 Cells to Tumor Necrosis Factor-α-mediated Cytotoxicity* (1997) (116)
Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes (2006) (114)
Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status. (2016) (113)
Fas-mediated apoptosis in cultured human eosinophils. (1996) (112)
The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray (2011) (111)
Transfer of the murine interleukin-12 gene in vivo by a Semliki Forest virus vector induces B16 tumor regression through inhibition of tumor blood vessel formation monitored by Doppler ultrasonography (1999) (111)
Isolation of tumor-specific cytotoxic CD4+ and CD4+CD8dim+ T-cell clones infiltrating a cutaneous T-cell lymphoma (1998) (109)
Cutaneous T cell lymphoma reactive CD4+ cytotoxic T lymphocyte clones display a Th1 cytokine profile and use a fas-independent pathway for specific tumor cell lysis. (2000) (109)
Critical Role of Tumor Microenvironment in Shaping NK Cell Functions: Implication of Hypoxic Stress (2015) (106)
Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210. (2015) (106)
Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells. (2010) (106)
NK cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions (1998) (103)
HER-2/neu and hTERT Cryptic Epitopes as Novel Targets for Broad Spectrum Tumor Immunotherapy1 (2002) (100)
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 (2015) (97)
Cutting Edge: Hypoxia-Induced Nanog Favors the Intratumoral Infiltration of Regulatory T Cells and Macrophages via Direct Regulation of TGF-β1 (2013) (96)
ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy. (2014) (95)
Correlation between clinical response to interleukin 2 therapy and sustained production of tumor necrosis factor. (1990) (93)
Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs. (1999) (92)
Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression. (1994) (91)
Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function (1997) (91)
Generation of lymphokine-activated killer cells: synergy between tumor necrosis factor and interleukin 2. (1988) (90)
Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response. (2011) (88)
NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors1 (2005) (87)
Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. (2009) (87)
Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate. (1987) (87)
A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells. (1997) (86)
Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment (2017) (86)
Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment (2018) (85)
Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis. (2009) (83)
Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma. (2005) (82)
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 (2015) (81)
The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing* (2015) (81)
Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion (2017) (79)
Tumor-Infiltrating CD4+ T Lymphocytes Express APO2 Ligand (APO2L)/TRAIL upon Specific Stimulation with Autologous Lung Carcinoma Cells: Role of IFN-α on APO2L/TRAIL Expression and -Mediated Cytotoxicity1 (2002) (78)
Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas. (2000) (77)
TLR Ligands Stimulation Protects MSC from NK Killing (2014) (77)
Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism. (1994) (76)
Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells. (1997) (76)
STEAP, a prostate tumor antigen, is a target of human CD8+ T cells (2006) (75)
Differentiation therapy: targeting human renal cancer stem cells with interleukin 15. (2011) (74)
Generation of CTL Recognizing an HLA-A*0201-Restricted Epitope Shared by MAGE-A1, -A2, -A3, -A4, -A6, -A10, and -A12 Tumor Antigens: Implication in a Broad-Spectrum Tumor Immunotherapy1 (2002) (74)
ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway. (2008) (72)
Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer-Mediated Cytotoxicity. (2018) (72)
Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune? (2010) (72)
Autophagic degradation of GZMB/granzyme B (2014) (71)
Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors. (2005) (71)
Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution (2002) (68)
Isolation of tumor-specific cytotoxic CD4+ and CD4+CD8dim+ T-cell clones infiltrating a cutaneous T-cell lymphoma. (1998) (67)
TCR-engineered T cells to treat tumors: Seeing but not touching? (2016) (67)
Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway (2008) (67)
EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction (2013) (64)
Evidence for in situ expansion of diverse antitumor-specific cytotoxic T lymphocyte clones in a human large cell carcinoma of the lung. (2000) (63)
Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure (2006) (63)
Functional interaction between TGF-beta and IL-12 in human primary allogeneic cytotoxicity and proliferative response. (1997) (63)
Downregulation of interleukin-12 (IL-12) responsiveness in human T cells by transforming growth factor-beta: relationship with IL-12 signaling. (1999) (63)
Hypoxia-Dependent Inhibition of Tumor Cell Susceptibility to CTL-Mediated Lysis Involves NANOG Induction in Target Cells (2011) (62)
Evidence for tumor necrosis factor-alpha involvement in the optimal induction of class I allospecific cytotoxic T cells. (1990) (61)
More insights into the complex physiology of TNF. (1991) (61)
Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression. (2002) (60)
EphA2 as target of anticancer immunotherapy: identification of HLA-A*0201-restricted epitopes. (2003) (59)
Inducible Hsp70 as target of anticancer immunotherapy: Identification of HLA‐A*0201‐restricted epitopes (2004) (59)
Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells (2015) (59)
Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression (2014) (59)
Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies (2021) (58)
Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity (2017) (58)
Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction. (2002) (57)
The induction of nitric oxide by interleukin-12 and tumor necrosis factor-alpha in human natural killer cells: relationship with the regulation of lytic activity. (1998) (56)
Targeting hypoxia at the forefront of anticancer immune responses (2014) (56)
Role of Hypoxic Stress in Regulating Tumor Immunogenicity, Resistance and Plasticity (2018) (55)
Differential STAT3, STAT5, and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15: implications in the expression of functional molecules. (2003) (55)
In Situ Sensory Adaptation of Tumor-Infiltrating T Lymphocytes to Peptide-MHC Levels Elicits Strong Antitumor Reactivity1 (2005) (55)
Silencing of prion protein sensitizes breast adriamycin-resistant carcinoma cells to TRAIL-mediated cell death. (2007) (54)
Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity (2017) (54)
Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity (2014) (54)
Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity (2018) (54)
c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis. (2014) (53)
The Chemokine SDF‐1/CXCL12 Contributes to T Lymphocyte Recruitment in Human Pre‐ovulatory Follicles and Coordinates with Lymphocytes to Increase Granulosa Cell Survival and Embryo Quality (2005) (52)
The multifaceted role of autophagy in tumor evasion from immune surveillance (2016) (52)
Tumoral CD105 is a novel independent prognostic marker for prognosis in clear-cell renal cell carcinoma (2014) (51)
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT (2017) (51)
Generation of a Novel Regulatory NK Cell Subset from Peripheral Blood CD34+ Progenitors Promoted by Membrane-Bound IL-15 (2008) (51)
A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation. (2003) (51)
Cross-talk between Smad and p38 MAPK signalling in transforming growth factor β signal transduction in human glioblastoma cells (2007) (50)
Impairment of Fas‐antigen expression in adriamycin‐resistant but not TNF‐resistant MCF7 tumor cells (1996) (50)
Hypoxia-induced autophagy (2012) (48)
Chemokine Receptors Expression and Migration Potential of Tumor-infiltrating and Peripheral-expanded Vγ9Vδ2 T Cells From Renal Cell Carcinoma Patients (2008) (48)
The Decreased Susceptibility of Bcr/Abl Targets to NK Cell-Mediated Lysis in Response to Imatinib Mesylate Involves Modulation of NKG2D Ligands, GM1 Expression, and Synapse Formation1 (2006) (48)
Independent association of PD‐L1 expression with noninactivated VHL clear cell renal cell carcinoma—A finding with therapeutic potential (2017) (47)
Antitumor cytotoxic T‐lymphocyte response in human lung carcinoma: identification of a tumor‐associated antigen (2002) (47)
Integrating tumor hypoxic stress in novel and more adaptable strategies for cancer immunotherapy. (2020) (47)
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells (2020) (46)
Crosstalk between CTC, Immune System and Hypoxic Tumor Microenvironment (2014) (44)
Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: relationship with c-myc and Rb (1999) (44)
Human CD5 Protects Circulating Tumor Antigen-Specific CTL from Tumor-Mediated Activation-Induced Cell Death1 (2007) (44)
CD103+CD8+ TRM Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17 (2020) (44)
Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor alpha chain, epithelial-to-mesenchymal transition. (2009) (43)
Quantitative analysis of T helper 1, T helper 2, and inflammatory cytokine expression in patients after allogeneic bone marrow transplantation: relationship with the occurrence of acute graft-versus-host disease. (1997) (43)
CD158 receptor controls cytotoxic T-lymphocyte susceptibility to tumor-mediated activation-induced cell death by interfering with Fas signaling. (2003) (43)
Tumor plasticity interferes with anti-tumor immunity. (2014) (43)
Differential effect of anti-beta 2-microglobulin on IL 2 production and IL 2 receptor expression in the primary mixed lymphocyte culture reaction. (1985) (41)
Identification of HER‐2/neu immunogenic epitopes presented by renal cell carcinoma and other human epithelial tumors (2001) (41)
A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor (2011) (41)
Mutant α-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma (2004) (41)
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy (2021) (41)
Prevention of autoimmunity and control of recall response to exogenous antigen by Fas death receptor ligand expression on T cells. (2008) (41)
Human NK Cells Lyse Organ-Specific Endothelial Cells: Analysis of Adhesion and Cytotoxic Mechanisms1 (2005) (40)
AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity (2019) (40)
Opposite effects of estrogen receptors alpha and beta on MCF-7 sensitivity to the cytotoxic action of TNF and p53 activity (2005) (39)
Tumor escape from killing: role of killer inhibitory receptors and acquisition of tumor resistance to cell death. (2002) (38)
Activation of cytotoxic T-cell receptor γδ T lymphocytes in response to specific stimulation in myelodysplastic syndromes (2008) (38)
BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC) (2018) (38)
Analysis of the natural killer mediated immune response in metastatic renal cell carcinoma patients (2004) (38)
Tumor cells regulate the lytic activity of tumor-specific cytotoxic t lymphocytes by modulating the inhibitory natural killer receptor function. (2001) (38)
Differential regulation of interleukin‐12‐and interleukin‐15‐induced natural killer cell activation by interleukin‐4 (1996) (38)
Potentiation of a Tumor Cell Susceptibility to Autologous CTL Killing by Restoration of Wild-Type p53 Function1 (2003) (37)
Efficacy of adjuvant chemotherapy according to Prion protein expression in patients with estrogen receptor-negative breast cancer. (2007) (37)
Prostaglandins E as modulators of the immune response. (1988) (37)
Granzyme B-induced Cell Death Involves Induction of p53 Tumor Suppressor Gene and Its Activation in Tumor Target Cells* (2007) (37)
In vitro and in vivo immunostimulatory potential of bone marrow-derived mast cells on B- and T-lymphocyte activation. (2000) (36)
Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO. (2002) (36)
The actin filament cross-linker L-plastin confers resistance to TNF-α in MCF-7 breast cancer cells in a phosphorylation-dependent manner (2009) (36)
Differential effect of high doses versus low doses of interleukin‐12 on the adoptive transfer of human specific cytotoxic T lymphocyte in autologous lung tumors engrafted into severe combined immunodeficiency disease–nonobese diabetic mice (2001) (36)
Model cell lines for the study of apoptosis in vitro. (2001) (36)
Improving the Outcome of Leukemia by Natural Killer Cell-Based Immunotherapeutic Strategies (2014) (35)
Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: relationship to Bcl-2 family and caspase activation (2006) (35)
Integrating the quality of the cytotoxic response and tumor susceptibility into the design of protective vaccines in tumor immunotherapy. (2003) (34)
The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy (2019) (34)
Granzyme B–Activated p53 Interacts with Bcl-2 To Promote Cytotoxic Lymphocyte–Mediated Apoptosis (2015) (34)
The autophagy sensor ITPR1 protects renal carcinoma cells from NK-mediated killing. (2015) (33)
Functional interactions of IL2 and TNF in the differentiation of LGL into lak effectors (1989) (33)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
A dose escalation phase 1 study of radiotherapy (RT) in combination with anti-cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody ipilimumab (Ipi) in patients (pts) with metastatic melanoma (2016) (32)
miR-210 and hypoxic microvesicles: Two critical components of hypoxia involved in the regulation of killer cells function. (2016) (32)
Attenuated Bacteria as Effectors in Cancer Immunotherapy (2008) (31)
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-κB activation and endothelial cell survival (2007) (31)
Gap Junction Communication between Autologous Endothelial and Tumor Cells Induce Cross-Recognition and Elimination by Specific CTL1 (2009) (31)
Cytotoxic Dendritic Cells Generated from Cancer Patients (2011) (31)
Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: expression of IL-12 in human tumor cells (1997) (30)
Control of the immune response by pro-angiogenic factors (2014) (30)
Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter (2017) (30)
Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway. (2008) (30)
Silencing of the transcription factor STAT3 sensitizes lung cancer cells to DNA damaging drugs, but not to TNFα- and NK cytotoxicity. (2013) (30)
Gene Expression Profiling Identifies Microphthalmia-Associated Transcription Factor (MITF) and Dickkopf-1 (DKK1) as Regulators of Microenvironment-Driven Alterations in Melanoma Phenotype (2014) (29)
Hypoxia-driven intratumor heterogeneity and immune evasion. (2020) (29)
p53 Potentiation of Tumor Cell Susceptibility to CTL Involves Fas and Mitochondrial Pathways1 (2005) (29)
Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing (2019) (29)
Altered natural killer cell differentiation in CD34+ progenitors from Chronic Myeloid Leukemia patients (2000) (28)
Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors (2015) (28)
The role of hypoxia in shaping the recruitment of proangiogenic and immunosuppressive cells in the tumor microenvironment (2018) (28)
Evidence for the Binding of a Biologically Active Interleukin-2 to Human α2-Macroglobulin (*) (1995) (28)
Regulation of major histocompatibility complex class I expression by NF-κB-related proteins in breast cancer cells (1998) (27)
Interleukin-15 Plays a Central Role in Human Kidney Physiology and Cancer through the γc Signaling Pathway (2012) (27)
Analysis of T‐cell‐receptor β‐chain‐gene usage in peripheral‐blood and tumor‐infiltrating lymphocytes from human non‐small‐cell lung carcinomas (1999) (27)
Early evaluation of natural killer activity in post-transplant acute myeloid leukemia patients (2010) (27)
Induction of tumor necrosis factor alpha expression in human T lymphocytes following ionizing gamma irradiation. (1996) (27)
Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function (2016) (27)
Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization (2017) (26)
Differential production of interleukin 10 during human immunodeficiency virus infection. (1996) (26)
Adenovirus‐mediated wild‐type‐p53‐gene expression sensitizes TNF‐resistant tumor cells to TNF‐induced cytotoxicity by altering the cellular redox state (2000) (25)
Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma (2003) (25)
Nanomedicine-based cancer immunotherapy: recent trends and future perspectives (2021) (24)
Cross-talk between Smad and p38 MAPK signalling in transforming growth factor beta signal transduction in human glioblastoma cells. (2007) (24)
Interleukin-12 in the pathogenesis and therapy of HIV disease. (1995) (24)
Detection of a Functional Hybrid Receptor γc/GM-CSFRβ in Human Hematopoietic CD34+ Cells (2003) (24)
Role of Fas and granule exocytosis pathways in tumor‐infiltrating T lymphocyte–induced apoptosis of autologous human lung‐carcinoma cells (2001) (24)
Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity (2021) (24)
Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: Role of caspase-8 and mitochondria (2002) (24)
Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells (2016) (23)
Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal homeostasis. (2013) (22)
Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: relationship to Bcl-2 family and caspase activation (2007) (22)
EVIDENCE THAT RESIDUAL HOST CELLS SURVIVING THE CONDITIONING REGIMEN TO ALLOGENEIC BONE MARROW TRANSPLANTATION INHIBIT DONOR HEMATOPOIESIS IN VITRO—THE ROLE OF TNF-α (1991) (22)
Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival (2021) (22)
Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance (2016) (21)
Isolation and characterization of renal cancer stem cells from patient-derived xenografts (2015) (21)
Mutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma. (2004) (21)
Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3 (2017) (21)
Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells. (2015) (21)
Membrane-bound interleukin (IL)-15 on renal tumor cells rescues natural killer cells from IL-2 starvation-induced apoptosis. (2007) (21)
Cytokeratin 18 expression pattern correlates with renal cell carcinoma progression: relationship with Snail. (2010) (20)
Effect of tumor growth factor-beta on NK receptor expression by allostimulated CD8+ T lymphocytes. (1999) (20)
Allogeneic T cell activation triggering by MHC class I antigens. (1988) (20)
A polyepitope DNA vaccine targeted to Her-2/ErbB-2 elicits a broad range of human and murine CTL effectors to protect against tumor challenge. (2007) (20)
Pulmonary edema and shock after high-dose aracytine-C for lymphoma; possible role of TNF-alpha and PAF. (1993) (20)
Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet (2016) (20)
Iron chelation decreases human immunodeficiency virus-1 Tat potentiated tumor necrosis factor-induced NF-kappa B activation in Jurkat cells. (1997) (19)
Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours (2018) (19)
Expression of EPHRIN-A1, SCINDERIN and MHC class I molecules in head and neck cancers and relationship with the prognostic value of intratumoral CD8+ T cells (2013) (19)
EMT in immuno-resistance (2015) (19)
The anti-angiogenic activity of IL-12 is increased in iNOS−/− mice and involves NK cells (2010) (19)
Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells. (2008) (19)
Tumor resistance to specific lysis: a major hurdle for successful immunotherapy of cancer. (2009) (19)
[Tumor necrosis factor: pleiotropic cytokine]. (1992) (18)
Association of AXL and PD-L1 Expression with Clinical Outcomes in Patients with Advanced Renal Cell Carcinoma Treated with PD-1 Blockade (2021) (18)
Critical stages of tumor growth regulation in transgenic mice harboring a hepatocellular carcinoma revealed by distinct patterns of tumor necrosis factor-alpha and transforming growth factor-beta mRNA production. (1997) (18)
An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment (2021) (18)
IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis. (1997) (18)
The sensitivity of renal cell carcinoma cells to interferon alpha correlates with p53-induction and involves Bax. (2005) (18)
Resistance to TNF-Induced Cytotoxicity Correlates with an Abnormal Cleavage of Cytosolic Phospholipase A21 (2000) (17)
Resistance of Tumor Cells to Cytolytic T Lymphocytes Involves Rho-GTPases and Focal Adhesion Kinase Activation* (2008) (17)
Serum levels and receptor expression of tumor necrosis factor-alpha following human allogeneic and autologous bone marrow transplantation. (1992) (17)
Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells (2019) (17)
p53 status correlates with histopathological response in patients with soft tissue sarcomas treated using isolated limb perfusion with TNF-alpha and melphalan. (2008) (16)
Hypoxia increases mutational load of breast cancer cells through frameshift mutations (2020) (16)
Partial purification and characterization of a tumor necrosis factor‐α converting activity (1997) (16)
Tandem multicomponent reactions toward the design and synthesis of novel antibacterial and cytotoxic motifs. (2013) (16)
Tumor necrosis factor‐mediated cell lysis in vitro: relationship to cAMP accumulation and guanine nucleotide‐binding proteins (1992) (16)
Role of calcium on interleukin-1 production by monocytes: its relevance during T cell proliferation. (1991) (16)
Modulating tumor-associated macrophages to enhance the efficacy of immune checkpoint inhibitors: A TAM-pting approach. (2021) (16)
miR-181a modulates acute myeloid leukemia susceptibility to natural killer cells (2015) (16)
Tumor Hypoxia: A Key Determinant of Microenvironment Hostility and a Major Checkpoint during the Antitumor Response. (2018) (15)
The development of human tumor‐cell resistance to TNF‐α does not confer resistance to cytokine‐induced cellular cytotoxic mechanisms (1992) (15)
The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes? (2022) (14)
Potentiation of tnf‐mediated cell killing by VP‐16: Relationship to DNA single‐strand break formation (1990) (13)
Serum interleukin-12 levels in patients undergoing allogeneic or autologous bone marrow transplantation. (1996) (13)
Expression of the T Cell Gamma Gene by a Functionally Defined Human T Cell Clone Characterization at DNA, RNA, and Cell Membrane Level (1988) (13)
Analysis of T-cell-receptor beta-chain-gene usage in peripheral-blood and tumor-infiltrating lymphocytes from human non-small-cell lung carcinomas. (1999) (13)
[TNF: antitumoral agent at the border lines of immunity and inflammation]. (1991) (13)
Pentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell Populations (2016) (13)
Breast cancer in Tunisia: association of body mass index with histopathological aspects of tumors. (2014) (13)
The immunosuppressive effect of vincristine on allostimulatory potential of human dendritic cells interferes with their function and survival. (2004) (13)
Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition (2022) (12)
Hypoxia differently modulates the release of mitochondrial and nuclear DNA (2020) (12)
Synaptic Release of CCL5 Storage Vesicles Triggers CXCR4 Surface Expression Promoting CTL Migration in Response to CXCL12 (2014) (11)
NIVOREN GETUG-AFU 26 translational study: Association of PD-1, AXL, and PBRM-1 with outcomes in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) treated with nivolumab (N). (2020) (11)
Cytotoxic T cells - stroma interactions. (2011) (11)
HIF-2α/ITPR1 axis: A new saboteur of NK-mediated lysis (2015) (11)
Tumour necrosis factor-α plasma levels after flavone acetic acid administration in man and mouse (1993) (11)
TCR alpha/beta and TCR gamma/delta CD4-/CD8- HLA-DR alloreactive CTL clones do not use Fas/Fas ligand pathway to lyse their specific target cells. (1996) (11)
Combination of bemcentinib (BGB324): A first-in-class selective oral AXL inhibitor, with pembrolizumab in patients with triple negative breast cancer and adenocarcinoma of the lung. (2018) (10)
Altered IFNgamma signaling and preserved susceptibility to activated natural killer cell-mediated lysis of BCR/ABL targets. (2005) (10)
Failure of TGF beta1 and IL-12 to regulate human FasL and mTNF alloreactive cytotoxic T-cell pathways. (2008) (10)
Inhibition of the human allogeneic mixed lymphocyte response by cyclosporin A: relationship with the IL-12 pathway. (1996) (10)
Attenuation of Soft-Tissue Sarcomas Resistance to the Cytotoxic Action of TNF-α by Restoring p53 Function (2012) (9)
In-vivo effect of the combination of tnf and adriamycin against a human breast cell-line expressing the mdr-phenotype. (1995) (9)
Interleukin‐4 differentially regulates interleukin‐2‐mediated and CD2‐mediated induction of human lymphokine‐activated killer effectors (1992) (9)
Generation of diverse mutated tumor antigen-specific cytotoxic T lymphocytes in a lung cancer patient with long survival. (2005) (9)
Increase Sensitivity to Cytotoxic Drugs B in Cancer Cells Does Not κ Stable Inhibition of Nuclear Factor Updated (1999) (8)
Off-target effects of plasmid-transcribed shRNAs on NFκB signaling pathway and cell survival of human melanoma cells (2013) (8)
TNF alpha enhancement of NK and LAK cell functions induced by high-dose IL-2 in human peripheral blood mononuclear cells from patients pretreated with alpha IFN + IL-2. (1990) (8)
hSMG-1 is a granzyme B-associated stress-responsive protein kinase (2011) (8)
Methyltransferase inhibitor S-adenosyl-L-homocysteine sensitizes human breast carcinoma MCF7 cells and related TNF-resistant derivatives to TNF-mediated cytotoxicity via the ceramide-independent pathway. (1999) (8)
Abstract 626: BGB324, a selective small molecule inhibitor of receptor tyrosine kinase AXL, abrogates tumor intrinsic and microenvironmental immune suppression and enhances immune checkpoint inhibitor efficacy in lung and mammary adenocarcinoma models (2017) (8)
Heterogeneity among human nasopharyngeal carcinoma cell lines for inflammatory cytokines mRNA expression levels. (1992) (8)
Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions1 (2015) (7)
Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity? (2021) (7)
Tumour necrosis factor-alpha plasma levels after flavone acetic acid administration in man and mouse. (1993) (7)
Partial purification and characterization of a tumor necrosis factor-alpha converting activity. (1997) (6)
Modulation of TNF-mediated cell lysis in vitro: further analysis of intracellular signaling. (1993) (6)
Induction of multiple CD8+ T cell responses against the inducible Hsp70 employing an Hsp70 oligoepitope peptide. (2007) (6)
The renal cell carcinoma lysis by a specific cytotoxic T cell clone is independent of the Fas/Fas-L cytotoxic pathway. (1996) (6)
Expression of CD94 by ex vivo-differentiated NK cells correlates with the in vitro and in vivo acquisition of cytotoxic features (2017) (6)
Regulation of gap junctions in melanoma and their impact on Melan-A/MART-1-specific CD8+ T lymphocyte emergence (2013) (6)
Cancer stem-like cells evade CD8+CD103+ tumor-resident memory T (TRM) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model (2022) (6)
[Immunotherapy of cancer: promise and reality]. (2006) (6)
Decoding cancer’s camouflage: epithelial-mesenchymal plasticity in resistance to immune checkpoint blockade (2020) (5)
Improved culture conditions for quantitative evaluation of interleukin 2 production by frozen human lymphocytes. (1983) (5)
[At the crossroads of cancer]. (2013) (5)
CD48 May serve as an accessory molecule for the activation of a subset of human γ/δ T cells (1996) (5)
Tumor escape from the immune response: a major hurdle for successful immunotherapy of cancer? (2005) (5)
Tumoral CD 105 is a novel independent prognostic marker for prognosis in clear-cell renal cell carcinoma (2018) (5)
[Immune response and cancer]. (2008) (5)
NIVOREN GETUG-AFU 26 translational study: CD8 infiltration and PD-L1 expression are associated with outcome in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) treated with nivolumab (N) (2019) (5)
Cancer-associated Fibroblasts and Modulation of the Antitumor Immune Response (2015) (5)
Resistance of Cancer Cells to CTL-Mediated Immunotherapy (2015) (5)
[Tumor hypoxia: a key player in the regulation of stromal and anti-tumor responses]. (2014) (4)
The decreased susceptibility of metastatic melanoma cells to killing involves an alteration of CTL reactivity. (2006) (4)
Waterpipe smoke condensate influences epithelial to mesenchymal transition and interferes with the cytotoxic immune response in non-small cell lung cancer cell lines (2021) (4)
Effect of nuclear factor κB inhibition on tumor cell sensitivity to natural killer‐mediated cytolytic function (2001) (4)
Role of p53 in the sensitization of tumor cells to apoptotic cell death. (2002) (4)
Isolation of Tumor-Specific Cytotoxic CD 4 1 and CD 4 1 CD 8 dim 1 T-Cell Clones Infiltrating a Cutaneous T-Cell Lymphoma (1998) (4)
Au carrefour du cancer (2013) (4)
[Tumor necrosis factor alpha (cachectin). Biological properties and role in physiopathology]. (1989) (4)
Vaccine Targeted to Her-2 / ErbB2 Elicits a Broad Range of Human and Murine CTL Effectors to Protect against Tumor Challenge (2007) (4)
Emerging Role of Hypoxia-Induced Autophagy in Cancer Immunotherapy (2014) (4)
Phenobarbital prevents the inhibitory effects of tumor necrosis factor on glutathione-S-transferase mu in primary culture rat hepatocytes. (1998) (4)
Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal cancer. (2011) (4)
Autophagy mediated danger signaling regulates tumor immunosurveillance and may potentiate the effects of anti-cancer immunotherapy through increased adjuvanticity (2020) (3)
Lack of correlation between serum levels and receptor expression of TNF alpha and graft versus host disease following allogeneic bone marrow transplantation. (1991) (3)
Abstract 3774: BGB324, a selective small-molecule inhibitor of receptor tyrosine kinase AXL, targets tumor immune suppression and enhances immune checkpoint inhibitor efficacy (2018) (3)
Mechanisms of Cytotoxic Lymphocyte-Mediated Apoptosis and Relationship with the Tumor Suppressor p53. (2015) (3)
Membrane-bound IL-15 stimulation on peripheral blood natural kiler progenitors leads to the generation of an adherent subset co-expressing dendritic cells and natural kiler functional markers (2011) (3)
Fresh blood Immune cell monitoring in patients treated with nivolumab in the GETUG-AFU26 NIVOREN study: Association with toxicity and treatment outcome (2019) (3)
The inhibitory effect of PGE2 on T cell activation is not associated with inhibition of PKC translocation. (1989) (3)
The Antitumor Cytotoxic Response: If the Killer Cells Play the Music, the Microenvironmental Hypoxia Plays the Tune. (2020) (3)
Functional and phenotypic modifications induced by IL-4, as single agent or in combination with IL-2, on PBMC preactivated in vivo by alpha-interferon + interleukin-2 therapy. (1990) (3)
Baseline circulating unswitched memory B cells and B-cell related soluble factors are associated with overall survival in patients with clear cell renal cell carcinoma treated with nivolumab within the NIVOREN GETUG-AFU 26 study (2022) (3)
The immunotherapy of cancer and tumor escape from immune surveillance. (2001) (3)
“Suffocating” tumors by blocking adaptation to hypoxia: a new headway in melanoma immunotherapy (2021) (2)
A dose escalation phase 1 study of radiotherapy (RT) in combination with anti-cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody ipilimumab in patients (pts) with metastatic melanoma. (2017) (2)
Abstract 5754: Hypoxia-induced tumor plasticity and immune resistance involves an alteration of target recognition by a mechanism involving TGF-beta signaling (2018) (2)
Designing Organoid Models to Monitor Cancer Progression, Plasticity and Resistance: The Right Set Up for the Right Question (2022) (2)
HLA-G Antigen Expression in Renal Carcinoma Tumor-specific Up-Regulation of the Nonclassical Class I Updated (2001) (2)
p53 reactivating small molecule PRIMA‑1MET/APR‑246 regulates genomic instability in MDA‑MB‑231 cells. (2022) (2)
Abstract OT1-01-03: A phase II multi-center study of BGB324 in combination with pembrolizumab in patients with previously treated, locally advanced and unresectable or metastatic triple negative breast cancer (TNBC) or triple negative inflammatory breast cancer (TN-IBC) (2018) (2)
Enhanced Cytotoxic Activity of Ex Vivo-differentiated Human Natural Killer Cells in the Presence of HOXB4 (2014) (2)
Multifaceted Role of the Transforming Growth Factor β on Effector T Cells and the Implication for CAR-T Cell Therapy (2021) (2)
Genomic Analysis of Waterpipe Smoke-Induced Lung Tumor Autophagy and Plasticity (2022) (2)
Tumor necrosis factor alpha: a costimulator for cytotoxic cell differentiation. (1991) (2)
Induction of multiple CD 8 + T cell responses against the inducible Hsp 70 employing an Hsp 70 oligoepitope peptide (1)
The expression of interleukin-2 receptor subunits on the different human peripheral blood mononuclear cell subsets displays a highly sensitive profile (1997) (1)
CD48 may serve as an accessory molecule for the activation of a subset of human gamma/delta T cells. (1996) (1)
SERUM LEVELS AND RECEPTOR EXPRESSION OF TUMOR NECROSIS FACTOR‐α FOLLOWING HUMAN ALLOGENEIC AND AUTOLOGOUS BONE MARROW TRANSPLANTATION (1992) (1)
Role of Autophagy in Tumor Progression and Regression (2016) (1)
Abstract 4994: Hypoxia-induced autophagy and TNF-alpha resistance in breast cancer cells leads to tumor evasion from NK-mediated immunosurveillance by downregulation of ICAM1. (2013) (1)
Editorial: The intricate innate immune-cancer cell relationship in the context of tumor angiogenesis, immunity and microbiota: The angiogenic switch in the tumor microenvironment as a key target for immunotherapies (2022) (1)
The Most Common VHL Point Mutation R167Q in Hereditary VHL Disease Interferes with Cell Plasticity Regulation (2021) (1)
[Tumor/cytotoxic effector cross-talk in the control of tumor susceptibility to lysis]. (2003) (1)
Editor's Note: ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy. (2022) (1)
Synaptic actin cytoskeleton remodeling: A novel mechanism for tumor cell escape from natural killer cell mediated death (2016) (1)
Editorial: Targeting the Tumor Microenvironment for a More Effective and Efficient Cancer Immunotherapy (2020) (1)
Expression of EPHRIN-A1, SCINDERIN and MHC class I molecules in head and neck cancers and relationship with the prognostic value of intratumoral CD8+T cells (2013) (1)
[Abnormal regulation in the production of IL2 in Hodgkin's disease]. (1985) (1)
The Promise of Targeting Hypoxia to Improve Cancer Immunotherapy: Mirage or Reality? (2022) (1)
Broad-Spectrum Tumor Immunotherapy-A 12 Tumor Antigens : Implication in a MAGE-A 1 ,-A 2 ,-A 3 ,-A 4 ,-A 6 ,-A 10 , and HLA-A * 0201-Restricted Epitope Shared by Generation of CTL Recognizing an (2002) (1)
Cellular and molecular immunology of an important regulatory cytokine. New York 9-12, November 1995. (1996) (1)
Role of hypoxia induced autophagy in the resistance of tumor cells to CTL-mediated specific lysis. (95.11) (2010) (1)
Functional interactions between interleukin‐4, interleukin‐2, and tumor necrosis factor‐al for lymphokine‐activated killer cell generation (1990) (1)
Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from (2013) (1)
Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy (2023) (1)
interaction preventing dynamic membrane reorganization in CTL / tumor cell Engagement of the inhibitory receptor CD 158 a interrupts TCR signaling (2002) (1)
Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours (2018) (0)
Lytic Activity Factor-? in Human Natural Killer Cells: Relationship With the Regulation of The Induction of Nitric Oxide by Interleukin-12 and Tumor Necrosis (2013) (0)
Study of Moesin regulation and effects in breast cancer cells (2016) (0)
THE ANTITUMOR POTENTIAL OF INTERLEUKIN-12 (1998) (0)
Aberrant Repertoire and Deficient Proliferation of TCR γδ T Cells in Myelodysplastic Syndromes (MDS). (2006) (0)
Autophagy Regulation of the Tumor Immunity – An Old Machinery for a New Function (2015) (0)
In Vitro Mimicking of IL-15 Delivery through Trans-Presentation Is a Potent Driver of NK Cell Expansion and Effector Functions (2016) (0)
CXCL 12 Promoting CTL Migration in Response to Triggers CXCR 4 Surface Expression Synaptic Release of CCL 5 Storage Vesicles (2014) (0)
Melanomas Epitope Presented by Breast Carcinomas and Recognition by Human CTL of a Wild-Type p53 Accumulation of the p53 Protein Allows (1997) (0)
Abstract 5679: Application of a hypoxia metric to investigate tumor mutational burden and cancer cell immunogenicity in vitro (2022) (0)
modulates their susceptibility to NK-mediated lysis c-Myc regulates expression of NKG 2 D ligands ULBP 1 / 2 / 3 in AML and (2014) (0)
Hypoxia as a potential inducer of immune tolerance and a driver of tumor mutational burden: Impact on cancer immunotherapy (2021) (0)
Fas Ligand De ﬁ ciency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells (2015) (0)
Chronic hypoxia is associated with transcriptomic reprogramming and increased genomic instability in cancer cells (2023) (0)
Hypoxia induced autophagy: A new regulator of the anti tumor immune response (2016) (0)
Pharmacological Potentiation of TNF-Mediated Cell Lysis in vitro (1992) (0)
The impact of baseline peripheral cytokines on survival in metastatic clear cell renal cell carcinoma (RCC) treated with nivolumab: NIVOREN GETUG-AFU 26 Translational study. (2022) (0)
Fas LigandDe fi ciency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells (2015) (0)
Correlation between Clinical Response to Interleukin 2 Therapy and Sustained Production of Tumor Necrosis Factor 1 (2006) (0)
Abstract 2995: Autophagy as a key driver of waterpipe smoke-induced lung cancer cell plasticity and resistance (2022) (0)
[Production of IL2 and induction of IL2 receptor: two independent and dissociable events during allogenic stimulation in vitro in man]. (1986) (0)
Cytosolic Phospholipase A Correlates with an Abnormal Cleavage of Resistance to TNF-Induced Cytotoxicity (2000) (0)
Microenvironment and Immunology Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells (2012) (0)
Abstract 3632: Targeting of tumor myeloid suppressor cells by Salmonella bacteria causes a shift to M1 phenotype and leads to inhibition of tumor growth (2014) (0)
[Cytokines: fundamental principles and therapeutic potentials]. (1994) (0)
Abstract 156: Autophagic degradation of granzyme B impairs NK-mediated killing of hypoxic tumor cells (2014) (0)
Waterpipe smoke condensate influences epithelial (2021) (0)
Antitumor Reactivity Peptide-MHC Levels Elicits Strong Tumor-Infiltrating T Lymphocytes to In Situ Sensory Adaptation (2005) (0)
Immunotherapy Resistance Mechanisms in Renal Cell Cancer (2014) (0)
Selection of tumor-resistant variants following sustained natural killer cell-mediated immune stress (2020) (0)
Tumor hypoxic stress, cellular plasticity and RKIP (2020) (0)
Regulation of gap junctions in melanoma and their impact on Melan-A/MART-1-specific CD8+ T lymphocyte emergence (2013) (0)
Novel Targets for Broad Spectrum Tumor and hTERT Cryptic Epitopes as neu HER-2 / (2002) (0)
inducing autophagy ITPR 1 protects renal cancer cells against natural killer cells (2014) (0)
Killer cells: lytic signalling pathways and regulation (2004) (0)
[Functional interaction between the tumor necrosis factor and interleukin 2 during induction of lymphokine activated killer cytotoxic activity]. (1988) (0)
CD 158 Receptor Controls Cytotoxic T-Lymphocyte Susceptibility to Tumor-Mediated Activation-Induced Cell Death by Interfering with Fas Signaling 1 (2003) (0)
Title Fas ligand deficiency impairs tumor immunity by promoting an accumulation of monocytic myeloid derived suppressor cells Running title : FasL affects MDSC numbers and subset distribution Author names (2015) (0)
Role of ITPR1/HIF-2{alpha} axis in protecting renal cancer cells against natural killer cells. (2015) (0)
Evaluation of TCR γ/δ T cells in the lysis of renal tumor cells (2005) (0)
β by Transforming Growth Factor- Downregulation of Interleukin-12 (IL-12) Responsiveness in Human T Cells (2013) (0)
IL2-Rα Chain Inhibitory Factor (p29) Produced by HIV-Infected Macrophages: Cell Target and Mode of Action (1993) (0)
A prognostic hypoxia gene signature is associated with a dampened tumour immune microenvironment in cervical cancer (2023) (0)
Detection of a Functional Hybrid Receptor (cid:2) c/GM-CSFR (cid:3) in Human Hematopoietic CD34 (cid:4) Cells (2003) (0)
PUB080 A Phase II Study of BGB324 in Combination with Pembrolizumab in Patients with Previously Treated Advanced Lung Adenocarcinoma (2017) (0)
MITF and MITF-dependent genes are highly up-regulated in melanospheres. (2014) (0)
Abstract 1911: Influence of gap-junction formation on melanoma specific-CD8 T cells function (2010) (0)
Targeting dominant and cryptic peptide epitopes from the telomerase catalytic subunit reveals anti-tumor responses and autoimmune phenomena (2000) (0)
State-of-the-art therapeutic strategies for targeting cancer stem cells in prostate cancer (2023) (0)
Dual effect of autophagy in the regulation of cell-mediated cytotoxicity (2020) (0)
[Human interleukin 2]. (1983) (0)
Hypoxic Stress: A Key Regulator of the Antitumor Cytotoxic Response Linking Immune Resistance to Immune Suppression (2014) (0)
Role of the receptor tyrosine kinase AXL in regulating antitumor response and relationship with hypoxic stress (2020) (0)
Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4 (cid:1) T cells (2008) (0)
Baseline circulating soluble factors as predictors of immune-related adverse events (irAEs) in patients (pts) with metastatic clear cell renal carcinoma (mRCC) treated with nivolumab: A translational NIVOREN GETUG-AFU 26 study. (2023) (0)
IL-12: basic concepts and role in hematopoiesis (1996) (0)
Dysrégulation de la production d'IL 2 dans la maladie de Hodgkin (1985) (0)
CXCL12Promoting CTL Migration in Response to Triggers CXCR4 Surface Expression Synaptic Release of CCL5 Storage Vesicles (2014) (0)
Off-target effects of plasmid-transcribed shRNAs on NFκB signaling pathway and cell survival of human melanoma cells (2013) (0)
Clinical responses and outcome of 110 consecutive isolated limb perfusion (ILP) with TNF-{alpha} and melphalan (M) for locally advanced soft tissue sarcomas (LASTS) of extremities at the Institut Gustave Roussy (2008) (0)
Infusion of Umbilical Cord Blood-Derived Natural Killer Cells in Immune-Deficient Mice for the Treatment of Resistant Acute Myeloid Leukaemia (2016) (0)
[Technological advances in immuno-oncology: from fundamental concepts to patient immunological monitoring]. (2001) (0)
Expression, and Synapse Formation Modulation of NKG2D Ligands, GM1 Response to Imatinib Mesylate Involves Targets to NK Cell-Mediated Lysis in The Decreased Susceptibility of Bcr/Abl (2005) (0)
Abstract A36: The cytolytic and anti-leukemic potential of ex vivo differentiated NK cells is confined in the CD94 positive population (2017) (0)
Abstract 4886: Targeting WNT1-inducible signaling pathway protein 2 (WISP2) alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression (2014) (0)
Lymphokines and cytokines: from clone to clinic. (1993) (0)
Epithelial-to-Mesenchymal Transition Chain , α to the Soluble Interleukin-15 Receptor Membrane-Bound Interleukin-15 that Induces , in Response Human Renal Cancer Cells Express a Novel (2009) (0)
Differential Sensitivity of CD4+ and CD8+ T Lymphocytes to Phorbol Myristate Acetate upon Anti-CD3 Stimulation: Evidence for a Distinct Signaling Pathway (1991) (0)
Edinburgh Research Explorer Detection of a functional hybrid receptor gamma c/GM-CSFR beta in human hematopoietic CD34(+) cells (2013) (0)
Cancer-associated Fibroblasts and Modulation of the Antitumor Immune (2015) (0)
Abstract 199: Increased killing potential of ex vivo differentiated human natural killer cells in the presence of HOXB4 (2014) (0)
IL2-R alpha chain inhibitory factor (p29) produced by HIV-infected macrophages: cell target and mode of action. (1993) (0)
[Involvement of tumor necrosis factor in the generation of LAK killer cells]. (1990) (0)
Lysis Tumor Susceptibility to CTL-Mediated Cell during Hypoxia Induced an Impairment of and STAT 3 α Hypoxia-Inducible Factor-1 The Cooperative Induction of Mami-Chouaib and (2009) (0)
in the expression of functional molecules hematopoietic progenitors by endogenous interleukin-15: implications B activation in human κ Differential STAT3, STAT5, and NF- (2013) (0)
- Induced Cell Death α from Tumor Necrosis Factor Prion Protein Prevents Human Breast Carcinoma Cell Line (2004) (0)
Abstract 1041: Restoration of p53 function in soft tissue sarcomas correlates with increased sensitivity to TNFα (2010) (0)
Abstract P2-04-08: BGB324, a selective small molecule inhibitor of the receptor tyrosine kinase AXL, enhances immune checkpoint inhibitor efficacy in mammary adenocarcinoma (2017) (0)
PGE2 Inhibition of Human T Lymphocytes Proliferation: Regulatory Effect of PGE2 on the Intra-Cellular Signaling Pathways (1988) (0)
Impairment of cytotoxic anti-tumor response by hypoxic stress (P2011) (2013) (0)
ROLE OF INTERLEUKIN-12 IN AIDS PATHOGENESIS (1999) (0)
Human tumor antigens: identification and use for cancer vaccine development (2001) (0)
687P NIVOREN GETUG-AFU 26 translational study: Baseline peripheral cytokines predict survival in metastatic clear cell renal carcinoma (RCC) treated with nivolumab (2021) (0)
TGF-beta1-induced expression of alphaE(CD103)beta7 integrin on Ag-specific tumor-infiltrating T lymphocytes promotes killing of E-cadherin-bearing tumor cells by triggering polarized cytotoxic granule exocytosis (50.22) (2007) (0)
Down-Regulation Presentation Correlated with Heat Shock Protein-70 Autologous CTLs Is Associated with Inefficient Antigen A Three-Dimensional Tumor Cell Defect in Activating (2003) (0)
Abstract 464: Hypoxia-induced miR-210 potentiates MDSC function through regulation of Arg1, Il-16 and Cxcl12, and promotes tumor growth (2015) (0)
Hypoxia differently modulates the release of mitochondrial and nuclear DNA (2020) (0)
[Cellular regulation of human interleukin-2 production]. (1982) (0)
Hypoxia: A Formidable Saboteur of the Anti-tumor Response (2015) (0)
Tumor escape from killing: Role of killer (2002) (0)

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