Samara Reck-Peterson
Researcher
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Biology
Samara Reck-Peterson's Degrees
- PhD Cell Biology University of California, San Francisco
- Bachelors Biology University of California, Santa Cruz
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(Suggest an Edit or Addition)According to Wikipedia, Samara Reck-Peterson is an American cell biologist and biophysicist. She is a Professor of Cellular and Molecular Medicine and Cell and Developmental Biology at the University of California, San Diego and an Investigator of the Howard Hughes Medical Institute. She is known for her contributions to our understanding of how dynein, an exceptionally large motor protein that moves many intracellular cargos, works and is regulated. She developed one of the first systems to produce recombinant dynein and discovered that, unlike other cytoskeletal motors, dynein can take a wide variety of step sizes, forward and back and even sideways. She lives in San Diego, California.
Samara Reck-Peterson's Published Works
Published Works
- Single-Molecule Analysis of Dynein Processivity and Stepping Behavior (2006) (609)
- Nuclear actin and actin-related proteins in chromatin remodeling. (2002) (415)
- The cytoplasmic dynein transport machinery and its many cargoes (2018) (377)
- Force-Induced Bidirectional Stepping of Cytoplasmic Dynein (2007) (375)
- Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters (2012) (372)
- Class V myosins. (2000) (280)
- Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor (2012) (229)
- Dynein achieves processive motion using both stochastic and coordinated stepping (2011) (217)
- Mechanism and regulation of cytoplasmic dynein. (2015) (198)
- Lis1 is an initiation factor for dynein-driven organelle transport (2012) (174)
- The Affinity of the Dynein Microtubule-binding Domain Is Modulated by the Conformation of Its Coiled-coil Stalk*[boxs] (2005) (167)
- Structural Basis for Microtubule Binding and Release by Dynein (2012) (164)
- Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin (2009) (154)
- Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation*S⃞ (2008) (142)
- The Yeast Class V Myosins, Myo2p and Myo4p, Are Nonprocessive Actin-Based Motors (2001) (135)
- Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8. (2011) (123)
- Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae. (2000) (120)
- Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction (2020) (101)
- The human cytoplasmic dynein interactome reveals novel activators of motility (2017) (97)
- Lis1 regulates dynein by sterically blocking its mechanochemical cycle (2014) (96)
- Microtubule-based transport in filamentous fungi. (2012) (93)
- Reconstitution of dynein transport to the microtubule plus end by kinesin (2014) (88)
- Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. (2004) (85)
- Human CFEOM1 Mutations Attenuate KIF21A Autoinhibition and Cause Oculomotor Axon Stalling (2014) (83)
- The tail of a yeast class V myosin, myo2p, functions as a localization domain. (1999) (82)
- Peroxisomes move by hitchhiking on early endosomes using the novel linker protein PxdA (2015) (75)
- Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein (2017) (69)
- Hitchhiking: A Non-Canonical Mode of Microtubule-Based Transport. (2017) (68)
- Lis1 promotes the formation of activated cytoplasmic dynein-1 complexes (2020) (59)
- Imaging single molecules using total internal reflection fluorescence microscopy (TIRFM). (2010) (54)
- Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C (2018) (48)
- Self-repair protects microtubules from their destruction by molecular motors (2018) (44)
- Aspergillus Myosin-V Supports Polarized Growth in the Absence of Microtubule-Based Transport (2011) (39)
- Characterization of the Mutagenic Spectrum of 4-Nitroquinoline 1-Oxide (4-NQO) in Aspergillus nidulans by Whole Genome Sequencing (2014) (39)
- Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. (2005) (33)
- Angular measurements of the dynein ring reveal a stepping mechanism dependent on a flexible stalk (2017) (33)
- Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body. (2008) (32)
- A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity (2014) (31)
- Engineered, harnessed, and hijacked: synthetic uses for cytoskeletal systems. (2012) (26)
- Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. (2004) (22)
- A minimal computational model for three-dimensional cell migration (2019) (18)
- Probing the force generation and stepping behavior of cytoplasmic Dynein. (2011) (18)
- Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS–Hook–FHIP complexes (2021) (16)
- Parkinson’s Disease-linked LRRK2 structure and model for microtubule interaction (2020) (14)
- Structural basis for cytoplasmic dynein-1 regulation by Lis1 (2021) (14)
- Cytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungi. (2015) (14)
- Hitching a Ride: Mechanics of Transport Initiation through Linker-Mediated Hitchhiking. (2020) (12)
- Motile Properties of Cytoplasmic Dynein (2012) (12)
- Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes (2018) (10)
- Lis1 promotes the formation of maximally activated cytoplasmic dynein-1 complexes (2019) (8)
- PxdA interacts with the DipA phosphatase to regulate peroxisome hitchhiking on early endosomes (2021) (8)
- Engineering defined motor ensembles with DNA origami. (2014) (8)
- Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules (2022) (8)
- Structural Biology of LRRK2 and its Interaction with Microtubules (2021) (7)
- Imaging single molecular motor motility with total internal reflection fluorescence microscopy (TIRFM). (2010) (6)
- Retraction for Reck-Peterson et al., Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae, PNAS 2004 101:1491-1495 (2004) (6)
- Optimizing microtubule arrangements for rapid cargo capture (2021) (4)
- Dynactin revealed (2015) (3)
- Hitchhiking Across Kingdoms: Cotransport of Cargos in Fungal, Animal, and Plant Cells. (2022) (3)
- Structures of human cytoplasmic dynein in complex with the lissencephaly 1 protein, LIS1 (2022) (3)
- Lis1 relieves cytoplasmic dynein-1 auto-inhibition by acting as a molecular wedge (2022) (3)
- Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL (2022) (2)
- Structure of LRRK1 and mechanisms of autoinhibition and activation (2022) (1)
- Lis1 has Two Distinct Modes of Regulating Dynein's Mechanochemical Cycle (2017) (1)
- PxdA interacts with the DipA phosphatase to regulate endosomal hitchhiking of peroxisomes (2020) (1)
- Determining single-molecule intensity as a function of power density. (2010) (1)
- Woronin body hitchhiking on early endosomes is dispensable for septal localization in Aspergillus nidulans. (2023) (1)
- Structural Basis for the Regulation of Microtubule-Binding Affinity by Cytoplasmic Dynein (2012) (1)
- Regulation of peroxisome and lipid droplet hitchhiking by PxdA and the DipA phosphatase (2020) (1)
- Phenotypic, molecular, functional, and structural aspects of novel DCX and LIS1 mutations causing the subcortical band heterotopia/lissencephaly (SBH/LIS) spectrum (P2.227) (2015) (0)
- The Regulatory Role of Lis1 on the Mechanics of Dynein Motility (2019) (0)
- Mechanisms of Regulating Cytoplasmic Dynein (2018) (0)
- Cytoplasmic Dynein Ring Tilting Detected by Combined polTIRF and Sub-Pixel Particle Tracking of Semiconductor Quantum Rods (2015) (0)
- Teaming up: from motors to people (2013) (0)
- Homology-Based Model of the Dynein Coiled-Coil Stalk in the 19:19 Configuration. (2005) (0)
- RNA recoding in cephalopods tailors microtubule motor protein function (2022) (0)
- Structural Basis for Cytoplasmic Dynein-1 Regulation by Lis 1 1 2 (0)
- Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes (2018) (0)
- Homology-Based Model of the Dynein Coiled-Coil Stalk in the 22:19 Configuration. (2005) (0)
- The cytoplasmic dynein transport machinery and its many cargoes (2018) (0)
- Hitching a Ride: Mechanics of Organelle Transport Through Linker-Mediated Hitchhiking (2019) (0)
- Lis1 Regulates Dynein as a Molecular Wedge (2014) (0)
- Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4 (2017) (0)
- Mechanism of Parkinson’s disease-linked LRRK2 microtubule binding (2022) (0)
- Editor's evaluation: High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism (2021) (0)
- Mechanism of Parkinson's Disease-Linked LRRK2's Interaction with Microtubules (2021) (0)
- The mechanism of Lis1-mediated regulation of dynein motility and force generation (2022) (0)
- Mathematical Model from A minimal computational model for three-dimensional cell migration (2019) (0)
- Regulation of Cytoplasmic Dynein by Lisl (2015) (0)
- Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP (2017) (0)
- using both stochastic and coordinated stepping. (2016) (0)
- Two Opposing Modes of Cytoplasmic Dynein Regulation by Lis1 (2018) (0)
- High affinity dynein microtubule binding domain - tubulin complex (2012) (0)
- Simultaneous Position and Orientation Imaging of Polarized Fluorescence from Rod-In-Rod Semiconductor Nanoparticles on Cytoplasmic Dynein (2014) (0)
- Time-resolved Cryo-EM visualizes snapshots of dynein's activation pathway. (2023) (0)
- Lis1 Uncouples Allosteric Communication Between Dynein's AAA+ Motor and Microtubule Binding Domains (2012) (0)
- Molecular motors: Shifting gears with light. (2014) (0)
- Mechanism and Regulation of Cytoplasmic Dynein (2010) (0)
- Supplementary material from "A minimal computational model for three-dimensional cell migration" (2019) (0)
- LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes (2020) (0)
- Chapter 8 Motile Properties of Cytoplasmic Dynein (2012) (0)
- Structures of human dynein in complex with the lissencephaly 1 protein, LIS1 (2023) (0)
- Woronin bodies move dynamically and bidirectionally by hitchhiking on early endosomes in Aspergillus nidulans (2023) (0)
- Corrections and Retraction (2004) (0)
- Lis1 binding regulates force-induced detachment of cytoplasmic dynein from microtubules (2022) (0)
- Molecular architecture of LRRK2 in association with cellular organelles. (2023) (0)
- Combined Poltirf and Sub-Pixel Particle Tracking of Cytoplasmic Dynein Supports a Winch-Like Stepping Mechanism (2016) (0)
- “Cortical” Dynein Can Capture And Pull On Dynamic Microtubule Ends In Vitro (2009) (0)
- Regulatory Proteins Enable the Kinesin Kip2 to Overpower Cytoplasmic Dynein (2014) (0)
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