Samuel h. Gellman
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Samuel h. Gellmanchemistry Degrees
Chemistry
#1838
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#2646
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Organic Chemistry
#241
World Rank
#299
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Chemistry
Samuel h. Gellman's Degrees
- PhD Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Samuel h. Gellman Influential?
(Suggest an Edit or Addition)Samuel h. Gellman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Crystal Structure of the β2Adrenergic Receptor-Gs protein complex (2011) (2589)
- Foldamers: A Manifesto (1998) (1768)
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor (2010) (1516)
- beta-Peptides: from structure to function. (2001) (1331)
- Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex (2010) (720)
- Foldamers with heterogeneous backbones. (2008) (557)
- Antibiotics: Non-haemolytic β-amino-acid oligomers (2000) (482)
- β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers (1996) (465)
- Residue-based control of helix shape in β-peptide oligomers (1997) (427)
- Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins (2010) (396)
- Mimicry of antimicrobial host-defense peptides by random copolymers. (2007) (363)
- Conformation-directing effects of a single intramolecular amide-amide hydrogen bond: variable-temperature NMR and IR studies on a homologous diamide series (1991) (332)
- Mimicry of Host-Defense Peptides by Unnatural Oligomers: Antimicrobial β-Peptides (2002) (302)
- Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions (1983) (249)
- Minimal model systems for β-sheet secondary structure in proteins (1998) (231)
- Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells* (2003) (225)
- Rules for Antiparallel β-Sheet Design: d-Pro-Gly Is Superior to l-Asn-Gly for β-Hairpin Nucleation1 (1998) (224)
- Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers (2009) (211)
- Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. (2002) (208)
- Artificial chaperones-protein refolding via sequential use of detergent and cyclodextrin (1995) (203)
- On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. (1991) (200)
- Artificial chaperone-assisted refolding of denatured-reduced lysozyme: modulation of the competition between renaturation and aggregation. (1996) (194)
- Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides. (2009) (193)
- Artificial Chaperone-assisted Refolding of Carbonic Anhydrase B (1996) (192)
- Interplay among Folding, Sequence, and Lipophilicity in the Antibacterial and Hemolytic Activities of α/β-Peptides (2007) (190)
- Intramolecular Hydrogen Bonding in Derivatives of .beta.-Alanine and .gamma.-Amino Butyric Acid; Model Studies for the Folding of Unnatural Polypeptide Backbones (1994) (189)
- Stereochemical Requirements for β-Hairpin Formation: Model Studies with Four-Residue Peptides and Depsipeptides (1996) (188)
- Insights on β-Hairpin Stability in Aqueous Solution from Peptides with Enforced Type I‘ and Type II‘ β-Turns (1997) (185)
- Diphenylprolinol methyl ether: a highly enantioselective catalyst for Michael addition of aldehydes to simple enones. (2005) (185)
- Tosylamidation of cyclohexane by a cytochrome P-450 model (1982) (177)
- Translocation of a beta-peptide across cell membranes. (2002) (170)
- Unexpected Relationships between Structure and Function in α,β-Peptides: Antimicrobial Foldamers with Heterogeneous Backbones (2004) (169)
- Catalytic hydrolysis of a phosphate triester by tetracoordinated zinc complexes. (1986) (159)
- Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers (1999) (158)
- PTH receptor-1 signalling—mechanistic insights and therapeutic prospects (2015) (155)
- Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. (2008) (154)
- Two Helical Conformations from a Single Foldamer Backbone: “Split Personality” in Short α/β‐Peptides (2004) (154)
- Targeting protein-protein interactions: lessons from p53/MDM2. (2007) (154)
- Helix bundle quaternary structure from alpha/beta-peptide foldamers. (2007) (153)
- Introduction: Molecular Recognition. (1997) (152)
- Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern (2014) (151)
- Modulation of hydrophobic interactions by proximally immobilized ions (2015) (145)
- Catalytic transamidation reactions compatible with tertiary amide metathesis under ambient conditions. (2009) (144)
- Catalytic transamidation under moderate conditions. (2003) (144)
- Role of membrane lipids in the mechanism of bacterial species selective toxicity by two α/β-antimicrobial peptides (2006) (141)
- Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: cocatalyst effects and evidence for an enamine intermediate. (2005) (139)
- Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure (1999) (139)
- β-Peptides: From Structure to Function (2001) (139)
- (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. (2007) (138)
- Use of a Designed Triple-Stranded Antiparallel β-Sheet To Probe β-Sheet Cooperativity in Aqueous Solution (1998) (136)
- Biocidal activity of polystyrenes that are cationic by virtue of protonation. (2004) (135)
- Chimeric (α/β + α)-Peptide Ligands for the BH3-Recognition Cleft of Bcl-xL: Critical Role of the Molecular Scaffold in Protein Surface Recognition (2005) (134)
- Formation of Short, Stable Helices in Aqueous Solution by β-Amino Acid Hexamers (1999) (133)
- Aromatic Stacking Interactions in Aqueous Solution: Evidence That neither Classical Hydrophobic Effects nor Dispersion Forces Are Important (1994) (132)
- High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. (2009) (130)
- Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. (2012) (130)
- A rationally designed aldolase foldamer. (2009) (130)
- Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids. (2008) (127)
- Length-dependent stability and strand length limits in antiparallel β-sheet secondary structure (2001) (120)
- Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. (2008) (120)
- Antifungal Activity from 14-Helical β-Peptides (2006) (119)
- Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids. (2006) (119)
- Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings. (2001) (117)
- Functionalized nitrogen atom transfer catalyzed by cytochrome P-450 (1985) (117)
- Antiparallel Sheet Formation in β-Peptide Foldamers: Effects of β-Amino Acid Substitution on Conformational Preference1 (1997) (116)
- Artificial Chaperone-assisted Refolding of Citrate Synthase* (1998) (108)
- Nylon-3 polymers with selective antifungal activity. (2013) (107)
- Nylon-3 polymers active against drug-resistant Candida albicans biofilms. (2015) (106)
- A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. (2012) (105)
- Stereospecific synthesis of conformationally constrained gamma-amino acids: new foldamer building blocks that support helical secondary structure. (2009) (104)
- Redox control of secondary structure in a designed peptide (1993) (102)
- NMR-Based Quantification of β-Sheet Populations in Aqueous Solution through Use of Reference Peptides for the Folded and Unfolded States (1999) (101)
- Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets (2020) (100)
- Residue Requirements for Helical Folding in Short α/β-Peptides: Crystallographic Characterization of the 11-Helix in an Optimized Sequence (2005) (99)
- 12-Helix Formation in Aqueous Solution with Short β-Peptides Containing Pyrrolidine-Based Residues (2000) (98)
- Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans (2014) (98)
- Ternary Nylon-3 Copolymers as Host-Defense Peptide Mimics: Beyond Hydrophobic and Cationic Subunits (2014) (97)
- Backbone modification of a polypeptide drug alters duration of action in vivo (2014) (95)
- Protein Prosthesis: A Semisynthetic Enzyme with a β-Peptide Reverse Turn (2002) (95)
- Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly (2008) (92)
- Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments (2000) (89)
- Antimicrobial 14-Helical β-Peptides: Potent Bilayer Disrupting Agents† (2004) (89)
- A Designed β‐Hairpin Containing a Natural Hydrophobic Cluster (2000) (89)
- A β-Peptide Reverse Turn that Promotes Hairpin Formation (1998) (87)
- Solution Conformations of Helix-Forming β-Amino Acid Homooligomers (2000) (87)
- Rational Development of β-Peptide Inhibitors of Human Cytomegalovirus Entry* (2006) (87)
- α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. (2015) (84)
- Analysis of the factors that stabilize a designed two‐stranded antiparallel β‐sheet (2002) (84)
- Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold (2015) (83)
- Discovery and mechanistic study of Al(III)-catalyzed transamidation of tertiary amides. (2008) (83)
- Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and protein infrared spectra. (2012) (82)
- Tandem facial amphiphiles for membrane protein stabilization. (2010) (82)
- Environment-independent 14-helix formation in short beta-peptides: striking a balance between shape control and functional diversity. (2003) (81)
- Toward beta-peptide tertiary structure: self-association of an amphiphilic 14-helix in aqueous solution. (2001) (81)
- Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling. (2012) (81)
- Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. (2005) (81)
- MIRROR IMAGE REVERSE TURNS PROMOTE BETA -HAIRPIN FORMATION (1994) (80)
- Stabilizing and destabilizing effects of phenylalanine --> F5-phenylalanine mutations on the folding of a small protein. (2006) (80)
- Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. (2005) (79)
- Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets (2021) (78)
- New Helical Foldamers: Heterogeneous Backbones with 1:2 and 2:1 α:β-Amino Acid Residue Patterns (2006) (78)
- Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. (2008) (76)
- Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. (2010) (75)
- Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation. (2001) (75)
- Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. (2002) (75)
- Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. (2005) (74)
- α-Helix mimicry with α/β-peptides. (2013) (74)
- Helix formation in preorganized beta/gamma-peptide foldamers: hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues. (2010) (73)
- A Potent α/β-Peptide Analogue of GLP-1 with Prolonged Action in Vivo (2014) (72)
- Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. (2009) (72)
- Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein–protein recognition: Application to the Bim BH3 domain (2008) (72)
- Application of Microwave Irradiation to the Synthesis of 14-Helical β-Peptides (2005) (72)
- Parallel sheet secondary structure in gamma-peptides. (2001) (71)
- Preferred side-chain constellations at antiparallel coiled-coil interfaces (2008) (69)
- Single-conformation infrared spectra of model peptides in the amide I and amide II regions: experiment-based determination of local mode frequencies and inter-mode coupling. (2012) (69)
- Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. (2011) (68)
- Energetic Superiority of Two-Center Hydrogen Bonding Relative To Three-Center Hydrogen Bonding in a Model System (1998) (68)
- Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation. (2008) (68)
- The mouse alpha-amylase multigene family. Sequence organization of members expressed in the pancreas, salivary gland and liver. (1982) (67)
- Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones. (2003) (67)
- Mechanism of Al(III)-catalyzed transamidation of unactivated secondary carboxamides. (2006) (66)
- Redox-Triggered Secondary Structure Changes in the Aggregated States of a Designed Methionine-Rich Peptide (1996) (65)
- Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides. (2004) (65)
- An Achiral Dipeptide Mimetic That Promotes .beta.-Hairpin Formation (1995) (65)
- Exploration of Backbone Space in Foldamers Containing α‐ and β‐Amino Acid Residues: Developing Protease‐Resistant Oligomers that Bind Tightly to the BH3‐Recognition Cleft of Bcl‐xL (2007) (63)
- Targeting recognition surfaces on natural proteins with peptidic foldamers. (2016) (63)
- Structure‐Guided Rational Design of α/β‐Peptide Foldamers with High Affinity for BCL‐2 Family Prosurvival Proteins (2013) (62)
- Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides (2007) (61)
- TiIV-mediated reactions between primary amines and secondary carboxamides: amidine formation versus transamidation. (2007) (61)
- Access to poly-beta-peptides with functionalized side chains and end groups via controlled ring-opening polymerization of beta-lactams. (2009) (60)
- Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. (2019) (59)
- Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles. (2010) (59)
- Theoretical and Experimental Circular Dichroic Spectra of the Novel Helical Foldamer Poly[(1R,2R)-trans-2-aminocyclopentanecarboxylic acid] (1998) (57)
- β-Turn and β-Hairpin Mimicry with Tetrasubstituted Alkenes (1999) (57)
- β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues. (2016) (57)
- Molecular architecture with functionalized β-peptide helices (2003) (57)
- Lyotropic Liquid Crystals from Designed Helical β-Peptides (2006) (56)
- Selective binding of TAR RNA by a Tat-derived beta-peptide. (2003) (56)
- Intramolecular amide stacking and its competition with hydrogen bonding in a small foldamer. (2009) (56)
- Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. (2007) (56)
- Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. (2002) (56)
- Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. (2001) (56)
- An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure. (2009) (55)
- Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound peptide. (2014) (55)
- Control of Hairpin Formation via Proline Configuration in Parallel β-Sheet Model Systems (2000) (54)
- Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-NHMe and Ac-beta3-hTyr-NHMe. (2008) (54)
- Synthetic Polymers Active against Clostridium difficile Vegetative Cell Growth and Spore Outgrowth (2014) (54)
- Interactions of the antimicrobial β‐peptide β‐17 with phospholipid vesicles differ from membrane interactions of magainins (2003) (53)
- Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane‐Protein Superassembly: Importance of Branching in the Hydrophilic Portion (2008) (53)
- Structural Basis of Bcl‐xL Recognition by a BH3‐Mimetic α/β‐Peptide Generated by Sequence‐Based Design (2011) (53)
- Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. (2002) (52)
- An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. (2001) (52)
- Accommodation of α-Substituted Residues in the β-Peptide 12-Helix: Expanding the Range of Substitution Patterns Available to a Foldamer Scaffold (2003) (51)
- Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. (2012) (51)
- Hydrogen-bond-mediated folding in depsipeptide models of .beta.-turns and .alpha.-helical turns (1993) (50)
- ANION AND ION PAIR COMPLEXATION BY A MACROCYCLIC PHOSPHINE OXIDE DISULFOXIDE (1994) (49)
- Structural and Thermodynamic Characterization of Temperature-Dependent Changes in the Folding Pattern of a Synthetic Triamide (1993) (48)
- Temperature-dependent changes in the folding pattern of a simple triamide (1990) (48)
- Lyotropic liquid crystals formed from ACHC-rich β-peptides. (2011) (48)
- Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bonds. (2003) (48)
- Tripod Amphiphiles for Membrane Protein Manipulation. (2010) (48)
- A Fluorescence Assay for Leucine Zipper Dimerization: Avoiding Unintended Consequences of Fluorophore Attachment (1999) (48)
- Foldamer-templated catalysis of macrocycle formation (2019) (48)
- Diversity in short beta-peptide 12-helices: high-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. (2001) (48)
- Thermodynamic analysis of .beta.-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride (1992) (47)
- Parallel Sheet Secondary Structure in β‐Peptides (2003) (47)
- HeLa Cell Entry by Guanidinium‐Rich β‐Peptides: Importance of Specific Cation–Cell Surface Interactions (2007) (47)
- An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis (2006) (47)
- An improved tripod amphiphile for membrane protein solubilization (2000) (47)
- Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. (2002) (47)
- Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain (2020) (47)
- Detection and analysis of chimeric tertiary structures by backbone thioester exchange: packing of an alpha helix against an alpha/beta-peptide helix. (2010) (46)
- Crystallographic Characterization of the a/-Peptide 14/15-Helix (2007) (46)
- Characterization of signal bias at the GLP‐1 receptor induced by backbone modification of GLP‐1 (2017) (46)
- Evidence that the β‐Peptide 14‐Helix is Stabilized by β3‐Residues with Side‐Chain Branching Adjacent to the β‐Carbon Atom (2002) (46)
- Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe. (2008) (46)
- Structural mimicry of the α-helix in aqueous solution with an isoatomic α/β/γ-peptide backbone. (2011) (46)
- Single-conformation and diastereomer specific ultraviolet and infrared spectroscopy of model synthetic foldamers: alpha/beta-peptides. (2009) (46)
- Indifference to Hydrogen Bonding in a Family of Secondary Amides (1997) (46)
- Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. (2006) (45)
- Searching for Minimum Increments of Hydrophobic Collapse: Flexible Dinaphthyl Carboxylates (1995) (45)
- An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. (2006) (45)
- Mini-proteins Trp the light fantastic (2002) (44)
- Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganization. (2011) (44)
- Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-stranded β-Sheets (2003) (44)
- Promotion of sheet formation in alpha-peptide strands by a beta-peptide reverse turn. (2000) (43)
- Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides (2014) (43)
- Solvent-dependent stabilization of the E configuration of propargylic secondary amides. (2000) (43)
- Crystallographic characterization of helical secondary structures in 2:1 and 1:2 alpha/beta-peptides. (2009) (43)
- Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences. (2011) (42)
- H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. (2007) (41)
- Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening. (2009) (41)
- Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking. (2012) (40)
- Asymmetric Synthesis of a New Helix‐Forming β‐Amino Acid: trans‐4‐Aminopiperidine‐3‐carboxylic Acid (2003) (40)
- Thermodynamic Stability of β-Peptide Helices and the Role of Cyclic Residues (2006) (39)
- A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides. (2014) (39)
- Building proficient enzymes with foldamer prostheses. (2014) (39)
- Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures. (2013) (39)
- Parallel synthesis of peptide libraries using microwave irradiation (2007) (39)
- Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. (2007) (39)
- An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. (2001) (39)
- Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers. (2013) (37)
- Titanium(IV)-Mediated Conversion of Carboxamides to Amidines and Implications for Catalytic Transamidation (2005) (36)
- Novel tripod amphiphiles for membrane protein analysis. (2013) (36)
- Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering. (2008) (35)
- Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups. (2010) (35)
- Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces. (2012) (35)
- Single-Cell, Time-Resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live Escherichia coli. (2016) (35)
- C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities. (2012) (35)
- Non-hydrogen-bonded secondary structure in beta-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. (1999) (34)
- Anatomy of a stable intramolecularly hydrogen bonded folding pattern (1991) (34)
- Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. (2009) (34)
- Synthesis and aggregation properties of a new family of amphiphiles with an unusual headgroup topology (1992) (34)
- Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents. (2015) (34)
- Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. (2006) (34)
- Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. (2014) (33)
- Enhanced nickel(II) chelation by gem-dimethyl-substituted macrocyclic tetrathioethers (1991) (33)
- Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics. (2015) (33)
- Side-chain pairing preferences in the parallel coiled-coil dimer motif: insight on ion pairing between core and flanking sites. (2010) (33)
- Broad distribution of energetically important contacts across an extended protein interface. (2011) (33)
- Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers. (2010) (32)
- Medium Effects on Minimum Inhibitory Concentrations of Nylon-3 Polymers against E. coli (2014) (32)
- Heterogeneous H-bonding in a foldamer helix. (2015) (32)
- A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. (2002) (32)
- Comparison of an HXH Three-Center Hydrogen Bond with Alternative Two-Center Hydrogen Bonds in a Model System (1999) (32)
- Single-conformation spectroscopy and population analysis of model γ-peptides: new tests of amide stacking. (2011) (32)
- Nylon-3 polymers that enable selective culture of endothelial cells. (2013) (31)
- Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. (2016) (31)
- Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. (2007) (31)
- A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides. (2015) (31)
- Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. (2012) (31)
- Distinctive circular dichroism signature for 14-helix-bundle formation by beta-peptides. (2008) (31)
- Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain. (2011) (31)
- Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. (2010) (31)
- Minimal model systems for beta sheet secondary structure in proteins. (1998) (30)
- Microwave-Assisted Parallel Synthesis of a 14-Helical β-Peptide Library (2006) (30)
- Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. (2001) (30)
- Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides (2008) (29)
- Nonadditive Interactions Mediated by Water at Chemically Heterogeneous Surfaces: Nonionic Polar Groups and Hydrophobic Interactions. (2017) (29)
- Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. (2014) (29)
- Structural Characterization of Thiocyclophanes That Promote Edge-to-Face Aromatic-Aromatic Geometries (1995) (29)
- A parallel beta-sheet model system that folds in water. (2001) (29)
- Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds. (2009) (28)
- New Charge-Bearing Amino Acid Residues That Promote β-Sheet Secondary Structure (2014) (28)
- Sheet-like assemblies of charged amphiphilic α/β-peptides at the air-water interface. (2011) (28)
- Improved glucose-neopentyl glycol (GNG) amphiphiles for membrane protein solubilization and stabilization. (2014) (28)
- Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water. (2013) (27)
- Mechanistic comparison of artificial-chaperone-assisted and unassisted refolding of urea-denatured carbonic anhydrase B. (1998) (27)
- Cyclic constraints on conformational flexibility in γ-peptides: conformation specific IR and UV spectroscopy. (2013) (27)
- Quantitative Analysis of Hydrophobically Induced Folding in a Minimal Model System (1997) (27)
- Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. (2005) (27)
- A Rapid 1H NMR Assay for Enantiomeric Excess of α-Substituted Aldehydes (2005) (27)
- Bacterial species selective toxicity of two isomeric α/β-peptides: Role of membrane lipids (2005) (27)
- Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. (2002) (27)
- High-resolution structures of a heterochiral coiled coil (2015) (27)
- Spectroscopic characterization of selected β- sheet hairpin models (2002) (26)
- Diacid linkers that promote parallel beta-sheet secondary structure in water. (2008) (26)
- Effects of backbone rigidification on intramolecular hydrogen bonding in a family of diamides (1993) (26)
- Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity. (2019) (25)
- Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. (2005) (25)
- Irreversible Agonist-Beta2 Adrenoceptor Complex (2011) (25)
- Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue. (2013) (24)
- Lyotropic liquid crystalline phases from helical β-peptides as alignment media. (2011) (24)
- Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution. (2016) (24)
- Intramolecular hydrogen bonding in simple diamides (1989) (24)
- Foldamer Catalysis. (2020) (24)
- Residue-based control of helix shape in beta-peptide oligomers. (1997) (24)
- Synthesis of beta-lactams bearing functionalized side chains from a readily available precursor. (2008) (23)
- Highly stable pleated-sheet secondary structure in assemblies of amphiphilic alpha/beta-peptides at the air-water interface. (2010) (23)
- Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. (2004) (23)
- Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives (1992) (23)
- Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. (2004) (23)
- Role of ring-constrained γ-amino acid residues in α/γ-peptide folding: single-conformation UV and IR spectroscopy. (2013) (23)
- Complexation of hexosammonium ions: evidence for contributions from OH.cntdot..cntdot..cntdot.OH hydrogen bonds in a hydroxylic medium (1993) (22)
- Receptor selectivity from minimal backbone modification of a polypeptide agonist (2018) (22)
- Establishing effective simulation protocols for beta- and alpha/beta-peptides. II. Molecular mechanical (MM) model for a cyclic beta-residue. (2008) (22)
- Evaluation of the Conformation-Directing Effects of Secondary Hydrogen-Bonding Interactions in Flexible Tetrapeptide Analogs (1995) (21)
- Thermodynamic Analysis of Autonomous Parallel β-Sheet Formation in Water (2006) (21)
- Rational development of beta-peptide inhibitors of human cytomegalovirus entry. (2006) (21)
- Incremental preorganization of a chelating macrocycle (1990) (21)
- Impact of Strand Number on Parallel β-Sheet Stability. (2015) (21)
- Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. (2004) (21)
- Kinetics of Anionic Ring-Opening Polymerization of Variously Substituted β-Lactams: Homopolymerization and Copolymerization (2010) (21)
- Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery (2014) (21)
- Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure. (2013) (21)
- Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. (2004) (20)
- Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange. (2007) (20)
- A Cationic Polymer That Shows High Antifungal Activity against Diverse Human Pathogens (2017) (20)
- Molecular structure and conformation of two acyclic polythioethers: Implications for the design of heavy metal chelators (1990) (20)
- Effects of Amphiphilic Topology on Self-Association in Solution, at the Air-Water Interface, and in the Solid State (1995) (20)
- Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation. (2018) (20)
- (R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. (2000) (20)
- Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation (2021) (20)
- The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif. (2012) (19)
- Antifungal activity from 14-helical beta-peptides. (2006) (19)
- Sequence Dependent Behavior of Amphiphilic β-Peptides on Gold Surfaces (2007) (19)
- Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist. (2016) (19)
- Inhibition of Ice Recrystallization by Nylon-3 Polymers. (2017) (19)
- Solution structure of a small protein containing a fluorinated side chain in the core (2006) (19)
- A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. (2008) (19)
- Mimicking the first turn of an α-helix with an unnatural backbone: conformation-specific IR and UV spectroscopy of cyclically constrained β/γ-peptides. (2014) (19)
- Structural Characterization of Peptide Oligomers Containing (1R,2S)‐2‐Aminocyclohexanecarboxylic Acid (cis‐ACHC) (2013) (19)
- Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers (2021) (19)
- Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes (2015) (19)
- Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization. (2013) (19)
- Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis. (2016) (19)
- Catalytic metathesis of simple secondary amides. (2007) (18)
- Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. (2005) (18)
- Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR (2020) (18)
- New evidence that the hydrophobic effect and dispersion are not major driving forces for nucleotide base stacking. (1996) (18)
- Impact of strand length on the stability of parallel-β-sheet secondary structure. (2011) (18)
- SPECTROMICROSCOPY AT THE ORGANIC-INORGANIC INTERFACE IN BIOMINERALS (2005) (17)
- Single-molecule force spectroscopy of β-peptides that display well-defined three-dimensional chemical patterns. (2011) (17)
- Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. (2015) (17)
- Optimization of a phosphine oxide disulfoxide array for multipoint hydrogen bonding to ammonium ions (1993) (17)
- Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams. (2012) (17)
- Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF (2017) (16)
- Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum. (2011) (15)
- Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor (2021) (15)
- Effect of a C-Terminal Cationic Group on the Competition between .alpha.-Helical Turn and .beta.-Turn in a Model Depsipeptide (1994) (15)
- Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. (2005) (15)
- Conformation-specific spectroscopy of capped glutamine-containing peptides: role of a single glutamine residue on peptide backbone preferences. (2016) (15)
- Improved treatment of cyclic β‐amino acids and successful prediction of β‐peptide secondary structure using a modified force field: AMBER*C (2000) (15)
- Hydrogen bonding in a family of triamides: conformation-directing effects in solution versus the solid state (1990) (15)
- Dipole-induced self-assembly of helical beta-peptides. (2008) (14)
- Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. (2012) (14)
- Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. (2004) (14)
- Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution. (2017) (14)
- Effects of amphiphile topology on aggregation properties : distinctive behavior of contrafacial amphiphiles (1993) (14)
- An autonomously folding β‐hairpin derived from the human YAP65 WW domain: Attempts to define a minimum ligand‐binding motif (2005) (14)
- Preparation of Protected syn-α,β-Dialkyl β-Amino Acids That Contain Polar Side Chain Functionality† (2003) (14)
- Differential Effects of β3 - versus β2 -Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides. (2018) (14)
- Helical secondary structures in 2:1 and 1:2 α/γ-peptide foldamers (2012) (14)
- Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. (2019) (14)
- Cationic Side Chain Identity Directs the Hydrophobically Driven Self-Assembly of Amphiphilic β-Peptides in Aqueous Solution. (2021) (13)
- Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. (2003) (13)
- Helix Propensities of Amino Acid Residues via Thioester Exchange. (2017) (13)
- Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides. (2018) (13)
- Crystallographic evidence for multiple coordinating conformations in a family of macrocyclic chelators (1991) (13)
- On the use of AM1 calculations for the study of intramolecular hydrogen bonding phenomena in simple amides (1992) (13)
- Thermodynamics of copper(II) complexation by macrocyclic tetrathioethers at 25.degree.C in water-methanol mixtures and acetonitrile: correlations of complexation enthalpy and ligand conformational preferences (1992) (13)
- Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils. (2012) (13)
- A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. (2019) (13)
- Evaluation of β‐Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure (2018) (13)
- Nickel(II) chelation by three bicyclic tetrathioethers : solution and solid-state data (1993) (13)
- Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. (2005) (13)
- Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. (2019) (12)
- Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. (2003) (12)
- Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. (2004) (12)
- Incorporation of β-Amino Acids Enhances the Antifungal Activity and Selectivity of the Helical Antimicrobial Peptide Aurein 1.2. (2017) (11)
- Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization, Stabilization and Crystallization (2013) (11)
- Using Constrained β‐Amino Acid Residues to Control β‐Peptide Shape and Function (2005) (11)
- Association of helical beta-peptides and their aggregation behavior from the potential of mean force in explicit solvent. (2009) (11)
- Macrocycles containing sulfur and phosphorus: Structure and complexation properties (1993) (11)
- Application of microwave irradiation to the synthesis of 14-helical beta-peptides. (2005) (11)
- Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. (2012) (11)
- Interaction of the Hydrophobic Tip of an Atomic Force Microscope with Oligopeptides Immobilized Using Short and Long Tethers. (2016) (11)
- Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi (2018) (11)
- Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase. (2016) (10)
- Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. (2008) (10)
- Molekulare Architektur mit funktionalisierten β‐Peptid‐Helices (2003) (10)
- Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. (2002) (9)
- Retention of Native Quaternary Structure in Racemic Melittin Crystals. (2019) (9)
- An unusual hydrogen bonding pattern in a crystallographically observed β-turn (1992) (9)
- Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. (2007) (9)
- Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. (2019) (9)
- Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. (2008) (9)
- Thermodynamic Scale of β-Amino Acid Residue Propensities for an α-Helix-like Conformation. (2018) (8)
- Strategies for Nonmacrocyclic Polythioether Ligands: New Pentacoordinating Architectures (1994) (8)
- Crystallographic characterization of N-oxide tripod amphiphiles. (2010) (8)
- Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability. (2021) (7)
- Detection and Analysis of Chimeric Tertiary Structures by Backbone Thioester Exchange: Packing of an α Helix against an α / β -Peptide Helix ** (2010) (7)
- Synthetic Studies on the 1,6-Methano[10]annulene Skeleton: A New Route That Provides Derivatives Substituted at the Bridge and on the Annulene Ring (1994) (7)
- Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection (2021) (7)
- Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion. (2014) (7)
- Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids (2019) (6)
- Molecular architecture with functionalized beta-peptide helices. (2003) (6)
- New synthesis of methano-bridged annulenes: access to highly substituted derivatives (1992) (6)
- Stereoselective oxidation of an eleven-membered heterocycle (1992) (6)
- Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. (2019) (6)
- Macrocyclic design strategies for small, stable parallel beta-sheet scaffolds. (2009) (6)
- Secondary Effects in Flexible Hydrogen Bonding Networks (1997) (6)
- STERIC CONTROL OF OXIDATION SELECTIVITY IN MACROCYCLIC PHOSPHINE OXIDE-DITHIOETHERS (1997) (6)
- Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. (2013) (6)
- Ammonolysis of anilides promoted by ethylene glycol and phosphoric acid (2014) (6)
- Synthesis and Aggregation Properties of a New Family of Amphiphiles with an Unusual Headgroup Topology. (1992) (6)
- Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum. (2021) (5)
- Electrophile-induced Berson-Willcott rearrangement of 11-carboxyl-1,6-methano[10]annulene methyl ester (1994) (5)
- Enantioselective Organocatalytic Aminomethylation of Aldehydes: A Role for Ionic Interactions and Efficient Access to β2-Amino Acids. (2006) (5)
- Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of Clostridioides difficile. (2021) (5)
- Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes. (2007) (5)
- Stereospecific Synthesis of Conformationally Constrained γ‐Amino Acids: New Foldamer Building Blocks That Support Helical Secondary Structure. (2010) (5)
- Lyotropic liquid crystals from designed helical beta-peptides. (2006) (5)
- On the use of molecular mechanics calculations for the study of intramolecular hydrogen bonding phenomena (1991) (4)
- Improved treatment of cyclic -amino acids and successful prediction of -peptide secondary structure using a modified force field: AMBER*C (2000) (4)
- Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments [J. Am. Chem. Soc. 2000, 122, 3995−4004]. (2001) (4)
- On the Hydrogen-Bonded Status of 2-Azacyclononanone and 2-Azacyclotridecanone in the Solid State (1994) (4)
- Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Isoxazolidones. (2003) (4)
- Backbone Modifications of HLA-A2-Restricted Antigens Induce Diverse Binding and T Cell Activation Outcomes. (2021) (4)
- Use of a Stereochemical Strategy to Probe the Mechanism of Phenol-Soluble Modulin A3 Toxicity (2019) (3)
- Mimicking the First Turn of an Alpha-Helix with an Unnatural Backbone: Conformation-Specific IR and UV Spectroscopy of Cyclically Constrained Beta/Gamma-Peptides (Dataset) (2014) (3)
- Effects of single α-to-β residue replacements on recognition of an extended segment in a viral fusion protein. (2020) (3)
- Toward a Soluble Model System for the Amyloid State. (2017) (3)
- Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. (2006) (3)
- Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy. (2020) (3)
- Parallel sheet secondary structure in beta-peptides. (2003) (3)
- Preparation of β2-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy. (2020) (3)
- Model systems: This year's model (2002) (3)
- Crystallographic characterization of the alpha/beta-peptide 14/15-helix. (2007) (3)
- Foldamers. Structure, Properties, and Applications. Edited by Stefan Hecht and Ivan Huc. (2008) (2)
- Functionalized Nitrogen Atom Transfer Catalyzed by Cytochrome P-450. (1986) (2)
- Erratum: Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups (Journal of the American Chemical Society (2010) 132 (13879-13885)) (2010) (2)
- Harnessing Noncovalent Interactions to Drive Single-Chain Nanoparticle Formation (2020) (2)
- An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quaternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions (2009) (2)
- Synthesis of 4,4‐Disubstituted 2‐Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12‐Helical β‐Peptides. (2005) (2)
- Thermodynamic analysis of autonomous parallel beta-sheet formation in water. (2006) (2)
- Role of Ring-Constrained Gamma-Amino Acid Residues in Alpha/Gamma-Peptide Folding: Single-Conformation UV and IR Spectroscopy (Dataset) (2015) (2)
- Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water. (2013) (2)
- Spectroscopic characterization of selected beta- sheet hairpin models. (2002) (2)
- Influence of immobilized cations on the thermodynamic signature of hydrophobic interactions at chemically heterogeneous surfaces (2020) (2)
- Catalytic Intramolecular Conjugate Additions of Aldehyde-Derived Enamines to α,β-Unsaturated Esters. (2020) (2)
- Thermodynamic stability of beta-peptide helices and the role of cyclic residues. (2006) (2)
- Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents. (2021) (2)
- Impact of Substitution Registry on the Receptor‐Activation Profiles of Backbone‐Modified Glucagon‐like Peptide‐1 Analogues (2019) (2)
- Comparisons of β‐Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands (2021) (2)
- New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns. (2006) (2)
- Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. (2003) (2)
- Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold. (2022) (2)
- NINETEEN a-Helix Mimicry with a / b-Peptides (2013) (1)
- Kinetic and Thermodynamic Insights on Agonist Interactions with the Parathyroid Hormone Receptor-1 from a New NanoBRET assay (2022) (1)
- Erratum: Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study (Chemical Communications (2013) 49 (2287-2289) DOI: 10.1039/c2cc36844g) (2013) (1)
- Diverse Impacts on Prokaryotic and Eukaryotic Membrane Activities from Hydrophobic Subunit Variation Among Nylon-3 Copolymers. (2020) (1)
- Preparation of Protected syn‐α,β‐Dialkyl β‐Amino Acids that Contain Polar Side Chain Functionality. (2003) (1)
- Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods (2023) (1)
- Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling. (2022) (1)
- Enantioselective Organocatalytic Aminomethylation of Aldehydes (2006) (1)
- A rapid 1H NMR assay for enantiomeric excess of alpha-substituted aldehydes. (2005) (1)
- Potential Foldamers Based on an ortho-Terphenyl Amino Acid. (2021) (1)
- Solution structure of a small protein containing a fluorinated side chain in the core. (2007) (1)
- Erratum: A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane protein (Chemistry - A European Journal (2012) 31) (2013) (1)
- Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence. (2005) (1)
- Formation of versus Recruitment to RNA-Rich Condensates: Controlling Effects Exerted by Peptide Side Chain Identity. (2022) (1)
- Correction to Synthesis of β-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor (2014) (1)
- Single-cell, Time-resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live E. coli (2016) (1)
- Synthetic Studies on the 1,6-Methano(10)annulene Skeleton: A New Route that Provides Derivatives Substituted at the Bridge and on the Annulene Ring. (1995) (1)
- Effects of Backbone Rigidification on Intramolecular Hydrogen Bonding in a Family of Diamides. (1993) (1)
- Erratum: An improved tripod amphiphile for membrane protein solubilization (Protein Science (2000) 9 (2518-2527)) (2001) (1)
- An Efficient Route to Either Enantiomer of Orthogonally Protected trans-3-Aminopyrrolidine-4-carboxylic Acid (V). (2001) (1)
- What Vesicle Leakage Reveals about Antimicrobial Activity (and What It Doesn't) (2015) (1)
- Local Rigidification and Possible Coacervation of the E. coli DNA by Cationic Nylon-3 Polymers. (2021) (1)
- Characterization of Hydrophobic Interactions of SARS-CoV-2 and MERS-CoV Spike Protein Fusion Peptides Using Single Molecule Force Measurements (2022) (1)
- Corrigendum to “Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-Stranded β-Sheets” (2003) (1)
- Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with HH4, an alpha/beta-Peptide with Irregular Secondary Structure (2019) (0)
- Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution (2018) (0)
- Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VI (2019) (0)
- Gas-Phase Folding of Small Glutamine Containing Peptides: Sidechain Hydrogen Bonding Stabilizes $\beta $-turns. (2017) (0)
- Solution structure of chicken villin headpiece subdomain containing a fluorinated side chain in the core (2006) (0)
- Zr(NMe2)4-Catalyzed Transamidationand Amide Metathesis Reactions (2009) (0)
- CONFORMATION-SPECIFIC SPECTROSCOPY OF A PROTOTYPICAL $\gamma$-PEPTIDE-WATER COMPLEX: Ac-$\gamma$$^{2}$-hPhe-NHMe-(H$_{2}$O)$_{1}$ (2010) (0)
- Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with one copy of HH4, an alpha/beta-Peptide with Irregular Secondary Structure (2020) (0)
- Conformation-Specific Infrared Spectroscopy of γ 2 -PEPTIDE Foldamers: Ac-γ 2 -hPhe-γ 2 -hAla-NHMe and Ac-γ 2 -hAla-γ 2 -hPhe-NHMe (2010) (0)
- Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 13 (2015) (0)
- Complex of 4-alpha/beta bound to gp41-5 (2012) (0)
- FUNCTIONALIZED BETA-LACTAM $ 93 . d } A 2 . ES SNR , et MONOMERS AND ANTIBACTERIAL ESA RE SERC COMPOSITIONS CONTAINING SAME 60 13758 A i / 2000 (2017) (0)
- Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL (2011) (0)
- alpha/beta foldamer in complex with Bcl-xL (2009) (0)
- A chimeric alpha+alpha/beta peptide based on the CHR domain sequence of gp41 (2011) (0)
- Effect of p-peptide inhibitors 10 um on HCMV Infection of NHDF (2017) (0)
- Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 (2011) (0)
- Toward design of a triple stranded antiparallel β-sheet (2002) (0)
- Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid (2013) (0)
- Corrections (2011) (0)
- Respiratory syncytial virus fusion protein N-terminal heptad repeat domain+VIQKI (2019) (0)
- Assembly of VIQKI D455(beta-L-homoaspartic acid)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
- Structure of Pin1 WW Domain Variant 1 with beta3-Ser Loop Substitution (2018) (0)
- Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly (2020) (0)
- Exploring backbone pattern in alpha/beta-peptide helix bundles: The GCN4-pLI side chain sequence on different (alpha-alpha-alpha-beta) backbones (2009) (0)
- Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. (2003) (0)
- Bcl-2 alpha beta-1 complex (2015) (0)
- Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo. (2022) (0)
- Racemic Phenol-Soluble Modulin Alpha 3 Peptide (2019) (0)
- A New Synthesis of Methano-Bridged Annulenes: Access to Highly Substituted Derivatives. (1992) (0)
- Inside Cover: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins (Chem. Eur. J. 31/2012) (2012) (0)
- Electrophile-Induced Berson-Willcott Rearrangement of 11-Carboxyl-1,6- methano(10)annulene Methyl Ester. (1994) (0)
- FOLDAMERS, CROWNS, AND WATER: CONNECTIONS BETWEEN ISOLATED MOLECULES AND SOLUTION-PHASE BEHAVIOR (2010) (0)
- United States Patent (2006) (0)
- Complex of 3-alpha bound to gp41-5 (2012) (0)
- Corrigendum: Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane‐Protein Superassembly: Importance of Branching in the Hydrophilic Portion (0)
- (Z)-2-(Benzoyl-aci-nitro)-2-phenylacetonitrile (1996) (0)
- CONFORMATION-SPECIFIC AND MASS-RESOLVED, INFRARED-POPULATION TRANSFER SPECTROSCOPY OF THE MODEL $\gamma^{2}$-PEPTIDE Ac-$\gamma$$^{2}$-hPhe-NHMe: EVIDENCE FOR THE PRESENCE OF INTRAMOLECULAR AMIDE-AMIDE STACKING INTERACTIONS. (2009) (0)
- Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2‐Amino Acids. (2008) (0)
- Cover Picture: Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design (ChemBioChem 13/2011) (2011) (0)
- In vitro and in vivo Inhibition of Herpes Simplex Virus Infection by Cationic Beta-Peptides (2008) (0)
- Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions. (2007) (0)
- Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI I454F I456F (2020) (0)
- Vascular endothelial growth factor in complex with alpha/beta-VEGF-1 (2015) (0)
- Puma BH3 foldamer in complex with Bcl-xL (2011) (0)
- MINIMIZED AVERAGE STRUCTURE OF DP-TT2 (2001) (0)
- NMR structure for a 2-stranded parallel beta-sheet (2015) (0)
- Crystal structure of alpha-beta foldamer 4c in complex with Bcl-xL (2011) (0)
- HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide (2009) (0)
- Structure and function in beta-peptide foldamers (2001) (0)
- SPECTROSCOPIC INVESTIGATION OF $\alpha$/$\beta$-PEPTIDES Ac-Phe-ACPC-NHMe AND Ac-ACPC-Phe-NHMe (2007) (0)
- Respiratory syncytial virus fusion glycoprotein N-terminal heptad repeat domain+VIQKI I456F (2020) (0)
- No . 1 Stereoselective Oxidation of an Eleven-Membered Heterocycle by (0)
- Assembly of VIQKI P5(beta-L-homoproline) with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
- Racemic M2-TM I39A crystallized from racemic detergent (2019) (0)
- Correction 174, p. 1047 (2006) (0)
- alpha/beta-Peptide helix crystallized from detergent solution: GCN4-pLI side chain sequence on an (alpha-alpha-beta-alpha-beta-alpha-beta) backbone with cyclic beta-residues (2009) (0)
- Co-assembly of VIQKI D452(beta-L-homoaspartic acid) with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
- CONFORMATION SPECIFIC SPECTROSCOPIC INVESTIGATION OF $\beta$- and $\alpha$/$\beta$-PEPTIDES: INSIGHT INTO THE AMIDE I AND AMIDE II SPECTRAL SIGNATURES (2008) (0)
- HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence (2009) (0)
- α/γ‐ペプチドのヘリックス構造形成におけるコンフォメーション制御されたγ‐アミノ酸ユニットの役割 (2013) (0)
- Villin headpiece subdomain with a Gln26 to beta-3-homoglutamine substitution (2016) (0)
- Analysis of Piscidin and Lipopolysaccharide Interactions: A Step Towards Characterizing Immunomodulation (2015) (0)
- Bcl-2 alpha beta-1 LINEAR complex (2015) (0)
- Racemic melittin (2019) (0)
- Villin headpiece subdomain with a Lys30 to beta-3-homolysine substitution (2016) (0)
- Structure of racemic Ala-(8,13,18) Magainin 2 (2013) (0)
- HIV gp41 six-helix bundle composed of an alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide (2009) (0)
- Racemic influenza M2-TM crystallized from monoolein lipidic cubic phase (2015) (0)
- alpha/beta-Peptide helix bundles: The GCN4-pLI side chain sequence on an (alpha-alpha-alpha-beta) backbone (2008) (0)
- Correction to “Crystallographic Characterization of N-Oxide Tripod Amphiphiles” (2013) (0)
- Bcl-xL bound to alpha beta Puma BH3 peptide 5 (2014) (0)
- Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI (2019) (0)
- NMR structure for a 3-stranded parallel beta-sheet (2015) (0)
- Correction to "Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold". (2022) (0)
- The Inherent Conformational Preferences of Glutamine-Containing Peptides: the Role for Side-Chain Backbone Hydrogen Bonds (2015) (0)
- Stereoselective Oxidation of an Eleven-Membered Heterocycle. (1992) (0)
- alpha/beta-Peptide helix bundles: A GCN4-pLI analogue with an (alpha-alpha-beta) backbone and cyclic beta residues (2008) (0)
- Crystal structure of racemic villin headpiece subdomain crystallized in space group P-1 (2012) (0)
- Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC (2018) (0)
- Crystal structure of racemic villin headpiece subdomain in space group I-4c2 (2012) (0)
- SINGLE-CONFORMATION SPECTROSCOPIC INVESTIGATION OF PEPTIDE BUILDING BLOCKS IN THE AMIDE I SPECTRAL REGION: COMPARISON OF EXPERIMENT TO DENSITY FUNCTIONAL THEORY AND THE TRANSITION DIPOLE COUPLING MODEL (2010) (0)
- Ammonolysis of Anilides Promoted by Ethylene Glycol and Phosphoric Acid. (2015) (0)
- Membrane Leakage and Antimicrobial Action of Polymers and Surfactants (2014) (0)
- Steric Control of Oxidation Selectivity in Macrocyclic Phosphine Oxide‐Dithioethers. (1998) (0)
- Villin headpiece subdomain with a Gln26 to ACPC substitution (2016) (0)
- Novel Pentacoordinating Polythioether Ligands - An Alternative to Macrocyclic Chelate Ligands. (1994) (0)
- Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to a gp41 NHR domain peptide (2011) (0)
- An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quarternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions - higher symmetry crystal (2009) (0)
- Assembly of VIQKI I456(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
- Correction to “Tandem Facial Amphiphiles for Membrane Protein Stabilization” (2013) (0)
- CONFORMATION AND DIASTEREOMERIC SPECIFIC SPECTROSCOPIC INVESTIGATION OF $\alpha$/$\beta$-PEPTIDES Ac-Phe-$\beta$$^{3}$-hAla-NHMe AND Ac-$\beta$$^{3}$-hAla-Phe-NHMe (2008) (0)
- Incremental Preorganization of a Chelating Macrocycle. (1990) (0)
- Crystal Structure of Quasiracemic Villin Headpiece Subdomain Containing (F5Phe10) Substitution (2012) (0)
- Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate (2013) (0)
- Cyclic residues in alpha/beta-peptide helix bundles: GCN4-pLI side chain sequence on an (alpha-alpha-beta) backbone with cyclic beta-residues at positions 1, 4, 10, 19 and 28 (2010) (0)
- Crystal structure of quasiracemic villin headpiece subdomain containing (F5Phe17) substitution (2012) (0)
- CONFORMATION-SPECIFIC UV and IR SPECTROSCOPY OF CONFORMATIONALLY CONSTRAINED $\alpha$/$\gamma$ PEPTIDE FOLDAMERS (2013) (0)
- SPECTROSCOPIC INVESTIGATION OF $\beta$-PEPTIDES: Ac-$\beta$$^3$-Phe-NHMe, Ac-$\beta$$^3$-Phe-$\beta$$^3$-Ala-NHMe AND Ac-$\beta$$^3$-Ala-$\beta$$^3$-Phe-NHMe (2007) (0)
- Location Bias in cAMP Signaling and its effects on Parathyroid Hormone Receptor Biological Effectiveness (2021) (0)
- Assembly of VIQKI I454(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
- Human parainfluenza virus type 3 fusion glycoprotein N-terminal heptad repeat domain+alpha/beta-VI (2021) (0)
- Access to γ2-Amino Acids (2008) (0)
- Synthesis and Structural Characterization of Helix‐Forming β‐Peptides: trans‐2‐Aminocyclopentanecarboxylic Acid Oligomers. (1999) (0)
- Trimeric helix bundle formed by an alpha/beta-peptide derivative of the HIV gp41 CHR domain (2009) (0)
- CONFORMATION-SPECIFIC INFRARED SPECTROSCOPY OF $\gamma^{2}$-PEPTIDE FOLDAMERS: Ac-$\gamma^{2}$-hPhe-$\gamma^{2}$-hAla-NHMe AND Ac-$\gamma^{2}$-hAla-$\gamma^{2}$-hPhe-NHMe (2010) (0)
- Complex of an alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 (2011) (0)
- Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 (2011) (0)
- An Improved Tripod Amphiphile for Membrane Protein Solubilization (2001) (0)
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