Samuel h. Gellman

Samuel h. Gellman's AcademicInfluence.com Rankings

Samuel h. Gellman

Chemistry

#1838

World Rank

#2646

Historical Rank

Organic Chemistry

#241

World Rank

#299

Historical Rank

chemistry Degrees

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Chemistry

Samuel h. Gellman's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Samuel h. Gellman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Crystal Structure of the β2Adrenergic Receptor-Gs protein complex (2011) (2589)
Foldamers: A Manifesto (1998) (1768)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor (2010) (1516)
beta-Peptides: from structure to function. (2001) (1331)
Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex (2010) (720)
Foldamers with heterogeneous backbones. (2008) (557)
Antibiotics: Non-haemolytic β-amino-acid oligomers (2000) (482)
β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers (1996) (465)
Residue-based control of helix shape in β-peptide oligomers (1997) (427)
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins (2010) (396)
Mimicry of antimicrobial host-defense peptides by random copolymers. (2007) (363)
Conformation-directing effects of a single intramolecular amide-amide hydrogen bond: variable-temperature NMR and IR studies on a homologous diamide series (1991) (332)
Mimicry of Host-Defense Peptides by Unnatural Oligomers: Antimicrobial β-Peptides (2002) (302)
Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions (1983) (249)
Minimal model systems for β-sheet secondary structure in proteins (1998) (231)
Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells* (2003) (225)
Rules for Antiparallel β-Sheet Design: d-Pro-Gly Is Superior to l-Asn-Gly for β-Hairpin Nucleation1 (1998) (224)
Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers (2009) (211)
Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. (2002) (208)
Artificial chaperones-protein refolding via sequential use of detergent and cyclodextrin (1995) (203)
On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. (1991) (200)
Artificial chaperone-assisted refolding of denatured-reduced lysozyme: modulation of the competition between renaturation and aggregation. (1996) (194)
Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides. (2009) (193)
Artificial Chaperone-assisted Refolding of Carbonic Anhydrase B (1996) (192)
Interplay among Folding, Sequence, and Lipophilicity in the Antibacterial and Hemolytic Activities of α/β-Peptides (2007) (190)
Intramolecular Hydrogen Bonding in Derivatives of .beta.-Alanine and .gamma.-Amino Butyric Acid; Model Studies for the Folding of Unnatural Polypeptide Backbones (1994) (189)
Stereochemical Requirements for β-Hairpin Formation: Model Studies with Four-Residue Peptides and Depsipeptides (1996) (188)
Insights on β-Hairpin Stability in Aqueous Solution from Peptides with Enforced Type I‘ and Type II‘ β-Turns (1997) (185)
Diphenylprolinol methyl ether: a highly enantioselective catalyst for Michael addition of aldehydes to simple enones. (2005) (185)
Tosylamidation of cyclohexane by a cytochrome P-450 model (1982) (177)
Translocation of a beta-peptide across cell membranes. (2002) (170)
Unexpected Relationships between Structure and Function in α,β-Peptides: Antimicrobial Foldamers with Heterogeneous Backbones (2004) (169)
Catalytic hydrolysis of a phosphate triester by tetracoordinated zinc complexes. (1986) (159)
Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers (1999) (158)
PTH receptor-1 signalling—mechanistic insights and therapeutic prospects (2015) (155)
Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. (2008) (154)
Two Helical Conformations from a Single Foldamer Backbone: “Split Personality” in Short α/β‐Peptides (2004) (154)
Targeting protein-protein interactions: lessons from p53/MDM2. (2007) (154)
Helix bundle quaternary structure from alpha/beta-peptide foldamers. (2007) (153)
Introduction: Molecular Recognition. (1997) (152)
Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern (2014) (151)
Modulation of hydrophobic interactions by proximally immobilized ions (2015) (145)
Catalytic transamidation reactions compatible with tertiary amide metathesis under ambient conditions. (2009) (144)
Catalytic transamidation under moderate conditions. (2003) (144)
Role of membrane lipids in the mechanism of bacterial species selective toxicity by two α/β-antimicrobial peptides (2006) (141)
Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: cocatalyst effects and evidence for an enamine intermediate. (2005) (139)
Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure (1999) (139)
β-Peptides: From Structure to Function (2001) (139)
(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. (2007) (138)
Use of a Designed Triple-Stranded Antiparallel β-Sheet To Probe β-Sheet Cooperativity in Aqueous Solution (1998) (136)
Biocidal activity of polystyrenes that are cationic by virtue of protonation. (2004) (135)
Chimeric (α/β + α)-Peptide Ligands for the BH3-Recognition Cleft of Bcl-xL: Critical Role of the Molecular Scaffold in Protein Surface Recognition (2005) (134)
Formation of Short, Stable Helices in Aqueous Solution by β-Amino Acid Hexamers (1999) (133)
Aromatic Stacking Interactions in Aqueous Solution: Evidence That neither Classical Hydrophobic Effects nor Dispersion Forces Are Important (1994) (132)
High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. (2009) (130)
Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. (2012) (130)
A rationally designed aldolase foldamer. (2009) (130)
Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids. (2008) (127)
Length-dependent stability and strand length limits in antiparallel β-sheet secondary structure (2001) (120)
Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. (2008) (120)
Antifungal Activity from 14-Helical β-Peptides (2006) (119)
Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids. (2006) (119)
Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings. (2001) (117)
Functionalized nitrogen atom transfer catalyzed by cytochrome P-450 (1985) (117)
Antiparallel Sheet Formation in β-Peptide Foldamers: Effects of β-Amino Acid Substitution on Conformational Preference1 (1997) (116)
Artificial Chaperone-assisted Refolding of Citrate Synthase* (1998) (108)
Nylon-3 polymers with selective antifungal activity. (2013) (107)
Nylon-3 polymers active against drug-resistant Candida albicans biofilms. (2015) (106)
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. (2012) (105)
Stereospecific synthesis of conformationally constrained gamma-amino acids: new foldamer building blocks that support helical secondary structure. (2009) (104)
Redox control of secondary structure in a designed peptide (1993) (102)
NMR-Based Quantification of β-Sheet Populations in Aqueous Solution through Use of Reference Peptides for the Folded and Unfolded States (1999) (101)
Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets (2020) (100)
Residue Requirements for Helical Folding in Short α/β-Peptides: Crystallographic Characterization of the 11-Helix in an Optimized Sequence (2005) (99)
12-Helix Formation in Aqueous Solution with Short β-Peptides Containing Pyrrolidine-Based Residues (2000) (98)
Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans (2014) (98)
Ternary Nylon-3 Copolymers as Host-Defense Peptide Mimics: Beyond Hydrophobic and Cationic Subunits (2014) (97)
Backbone modification of a polypeptide drug alters duration of action in vivo (2014) (95)
Protein Prosthesis: A Semisynthetic Enzyme with a β-Peptide Reverse Turn (2002) (95)
Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly (2008) (92)
Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments (2000) (89)
Antimicrobial 14-Helical β-Peptides: Potent Bilayer Disrupting Agents† (2004) (89)
A Designed β‐Hairpin Containing a Natural Hydrophobic Cluster (2000) (89)
A β-Peptide Reverse Turn that Promotes Hairpin Formation (1998) (87)
Solution Conformations of Helix-Forming β-Amino Acid Homooligomers (2000) (87)
Rational Development of β-Peptide Inhibitors of Human Cytomegalovirus Entry* (2006) (87)
α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. (2015) (84)
Analysis of the factors that stabilize a designed two‐stranded antiparallel β‐sheet (2002) (84)
Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold (2015) (83)
Discovery and mechanistic study of Al(III)-catalyzed transamidation of tertiary amides. (2008) (83)
Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and protein infrared spectra. (2012) (82)
Tandem facial amphiphiles for membrane protein stabilization. (2010) (82)
Environment-independent 14-helix formation in short beta-peptides: striking a balance between shape control and functional diversity. (2003) (81)
Toward beta-peptide tertiary structure: self-association of an amphiphilic 14-helix in aqueous solution. (2001) (81)
Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling. (2012) (81)
Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. (2005) (81)
MIRROR IMAGE REVERSE TURNS PROMOTE BETA -HAIRPIN FORMATION (1994) (80)
Stabilizing and destabilizing effects of phenylalanine --> F5-phenylalanine mutations on the folding of a small protein. (2006) (80)
Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. (2005) (79)
Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets (2021) (78)
New Helical Foldamers: Heterogeneous Backbones with 1:2 and 2:1 α:β-Amino Acid Residue Patterns (2006) (78)
Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. (2008) (76)
Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. (2010) (75)
Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation. (2001) (75)
Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. (2002) (75)
Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. (2005) (74)
α-Helix mimicry with α/β-peptides. (2013) (74)
Helix formation in preorganized beta/gamma-peptide foldamers: hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues. (2010) (73)
A Potent α/β-Peptide Analogue of GLP-1 with Prolonged Action in Vivo (2014) (72)
Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. (2009) (72)
Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein–protein recognition: Application to the Bim BH3 domain (2008) (72)
Application of Microwave Irradiation to the Synthesis of 14-Helical β-Peptides (2005) (72)
Parallel sheet secondary structure in gamma-peptides. (2001) (71)
Preferred side-chain constellations at antiparallel coiled-coil interfaces (2008) (69)
Single-conformation infrared spectra of model peptides in the amide I and amide II regions: experiment-based determination of local mode frequencies and inter-mode coupling. (2012) (69)
Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. (2011) (68)
Energetic Superiority of Two-Center Hydrogen Bonding Relative To Three-Center Hydrogen Bonding in a Model System (1998) (68)
Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation. (2008) (68)
The mouse alpha-amylase multigene family. Sequence organization of members expressed in the pancreas, salivary gland and liver. (1982) (67)
Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones. (2003) (67)
Mechanism of Al(III)-catalyzed transamidation of unactivated secondary carboxamides. (2006) (66)
Redox-Triggered Secondary Structure Changes in the Aggregated States of a Designed Methionine-Rich Peptide (1996) (65)
Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides. (2004) (65)
An Achiral Dipeptide Mimetic That Promotes .beta.-Hairpin Formation (1995) (65)
Exploration of Backbone Space in Foldamers Containing α‐ and β‐Amino Acid Residues: Developing Protease‐Resistant Oligomers that Bind Tightly to the BH3‐Recognition Cleft of Bcl‐xL (2007) (63)
Targeting recognition surfaces on natural proteins with peptidic foldamers. (2016) (63)
Structure‐Guided Rational Design of α/β‐Peptide Foldamers with High Affinity for BCL‐2 Family Prosurvival Proteins (2013) (62)
Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides (2007) (61)
TiIV-mediated reactions between primary amines and secondary carboxamides: amidine formation versus transamidation. (2007) (61)
Access to poly-beta-peptides with functionalized side chains and end groups via controlled ring-opening polymerization of beta-lactams. (2009) (60)
Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. (2019) (59)
Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles. (2010) (59)
Theoretical and Experimental Circular Dichroic Spectra of the Novel Helical Foldamer Poly[(1R,2R)-trans-2-aminocyclopentanecarboxylic acid] (1998) (57)
β-Turn and β-Hairpin Mimicry with Tetrasubstituted Alkenes (1999) (57)
β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues. (2016) (57)
Molecular architecture with functionalized β-peptide helices (2003) (57)
Lyotropic Liquid Crystals from Designed Helical β-Peptides (2006) (56)
Selective binding of TAR RNA by a Tat-derived beta-peptide. (2003) (56)
Intramolecular amide stacking and its competition with hydrogen bonding in a small foldamer. (2009) (56)
Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. (2007) (56)
Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. (2002) (56)
Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. (2001) (56)
An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure. (2009) (55)
Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound peptide. (2014) (55)
Control of Hairpin Formation via Proline Configuration in Parallel β-Sheet Model Systems (2000) (54)
Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-NHMe and Ac-beta3-hTyr-NHMe. (2008) (54)
Synthetic Polymers Active against Clostridium difficile Vegetative Cell Growth and Spore Outgrowth (2014) (54)
Interactions of the antimicrobial β‐peptide β‐17 with phospholipid vesicles differ from membrane interactions of magainins (2003) (53)
Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane‐Protein Superassembly: Importance of Branching in the Hydrophilic Portion (2008) (53)
Structural Basis of Bcl‐xL Recognition by a BH3‐Mimetic α/β‐Peptide Generated by Sequence‐Based Design (2011) (53)
Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. (2002) (52)
An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. (2001) (52)
Accommodation of α-Substituted Residues in the β-Peptide 12-Helix: Expanding the Range of Substitution Patterns Available to a Foldamer Scaffold (2003) (51)
Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. (2012) (51)
Hydrogen-bond-mediated folding in depsipeptide models of .beta.-turns and .alpha.-helical turns (1993) (50)
ANION AND ION PAIR COMPLEXATION BY A MACROCYCLIC PHOSPHINE OXIDE DISULFOXIDE (1994) (49)
Structural and Thermodynamic Characterization of Temperature-Dependent Changes in the Folding Pattern of a Synthetic Triamide (1993) (48)
Temperature-dependent changes in the folding pattern of a simple triamide (1990) (48)
Lyotropic liquid crystals formed from ACHC-rich β-peptides. (2011) (48)
Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bonds. (2003) (48)
Tripod Amphiphiles for Membrane Protein Manipulation. (2010) (48)
A Fluorescence Assay for Leucine Zipper Dimerization: Avoiding Unintended Consequences of Fluorophore Attachment (1999) (48)
Foldamer-templated catalysis of macrocycle formation (2019) (48)
Diversity in short beta-peptide 12-helices: high-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. (2001) (48)
Thermodynamic analysis of .beta.-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride (1992) (47)
Parallel Sheet Secondary Structure in β‐Peptides (2003) (47)
HeLa Cell Entry by Guanidinium‐Rich β‐Peptides: Importance of Specific Cation–Cell Surface Interactions (2007) (47)
An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis (2006) (47)
An improved tripod amphiphile for membrane protein solubilization (2000) (47)
Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. (2002) (47)
Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain (2020) (47)
Detection and analysis of chimeric tertiary structures by backbone thioester exchange: packing of an alpha helix against an alpha/beta-peptide helix. (2010) (46)
Crystallographic Characterization of the a/-Peptide 14/15-Helix (2007) (46)
Characterization of signal bias at the GLP‐1 receptor induced by backbone modification of GLP‐1 (2017) (46)
Evidence that the β‐Peptide 14‐Helix is Stabilized by β3‐Residues with Side‐Chain Branching Adjacent to the β‐Carbon Atom (2002) (46)
Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe. (2008) (46)
Structural mimicry of the α-helix in aqueous solution with an isoatomic α/β/γ-peptide backbone. (2011) (46)
Single-conformation and diastereomer specific ultraviolet and infrared spectroscopy of model synthetic foldamers: alpha/beta-peptides. (2009) (46)
Indifference to Hydrogen Bonding in a Family of Secondary Amides (1997) (46)
Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. (2006) (45)
Searching for Minimum Increments of Hydrophobic Collapse: Flexible Dinaphthyl Carboxylates (1995) (45)
An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. (2006) (45)
Mini-proteins Trp the light fantastic (2002) (44)
Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganization. (2011) (44)
Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-stranded β-Sheets (2003) (44)
Promotion of sheet formation in alpha-peptide strands by a beta-peptide reverse turn. (2000) (43)
Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides (2014) (43)
Solvent-dependent stabilization of the E configuration of propargylic secondary amides. (2000) (43)
Crystallographic characterization of helical secondary structures in 2:1 and 1:2 alpha/beta-peptides. (2009) (43)
Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences. (2011) (42)
H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. (2007) (41)
Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening. (2009) (41)
Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking. (2012) (40)
Asymmetric Synthesis of a New Helix‐Forming β‐Amino Acid: trans‐4‐Aminopiperidine‐3‐carboxylic Acid (2003) (40)
Thermodynamic Stability of β-Peptide Helices and the Role of Cyclic Residues (2006) (39)
A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides. (2014) (39)
Building proficient enzymes with foldamer prostheses. (2014) (39)
Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures. (2013) (39)
Parallel synthesis of peptide libraries using microwave irradiation (2007) (39)
Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. (2007) (39)
An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. (2001) (39)
Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers. (2013) (37)
Titanium(IV)-Mediated Conversion of Carboxamides to Amidines and Implications for Catalytic Transamidation (2005) (36)
Novel tripod amphiphiles for membrane protein analysis. (2013) (36)
Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering. (2008) (35)
Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups. (2010) (35)
Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces. (2012) (35)
Single-Cell, Time-Resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live Escherichia coli. (2016) (35)
C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities. (2012) (35)
Non-hydrogen-bonded secondary structure in beta-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. (1999) (34)
Anatomy of a stable intramolecularly hydrogen bonded folding pattern (1991) (34)
Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. (2009) (34)
Synthesis and aggregation properties of a new family of amphiphiles with an unusual headgroup topology (1992) (34)
Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents. (2015) (34)
Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. (2006) (34)
Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. (2014) (33)
Enhanced nickel(II) chelation by gem-dimethyl-substituted macrocyclic tetrathioethers (1991) (33)
Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics. (2015) (33)
Side-chain pairing preferences in the parallel coiled-coil dimer motif: insight on ion pairing between core and flanking sites. (2010) (33)
Broad distribution of energetically important contacts across an extended protein interface. (2011) (33)
Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers. (2010) (32)
Medium Effects on Minimum Inhibitory Concentrations of Nylon-3 Polymers against E. coli (2014) (32)
Heterogeneous H-bonding in a foldamer helix. (2015) (32)
A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. (2002) (32)
Comparison of an HXH Three-Center Hydrogen Bond with Alternative Two-Center Hydrogen Bonds in a Model System (1999) (32)
Single-conformation spectroscopy and population analysis of model γ-peptides: new tests of amide stacking. (2011) (32)
Nylon-3 polymers that enable selective culture of endothelial cells. (2013) (31)
Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. (2016) (31)
Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. (2007) (31)
A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides. (2015) (31)
Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. (2012) (31)
Distinctive circular dichroism signature for 14-helix-bundle formation by beta-peptides. (2008) (31)
Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain. (2011) (31)
Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. (2010) (31)
Minimal model systems for beta sheet secondary structure in proteins. (1998) (30)
Microwave-Assisted Parallel Synthesis of a 14-Helical β-Peptide Library (2006) (30)
Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. (2001) (30)
Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides (2008) (29)
Nonadditive Interactions Mediated by Water at Chemically Heterogeneous Surfaces: Nonionic Polar Groups and Hydrophobic Interactions. (2017) (29)
Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. (2014) (29)
Structural Characterization of Thiocyclophanes That Promote Edge-to-Face Aromatic-Aromatic Geometries (1995) (29)
A parallel beta-sheet model system that folds in water. (2001) (29)
Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds. (2009) (28)
New Charge-Bearing Amino Acid Residues That Promote β-Sheet Secondary Structure (2014) (28)
Sheet-like assemblies of charged amphiphilic α/β-peptides at the air-water interface. (2011) (28)
Improved glucose-neopentyl glycol (GNG) amphiphiles for membrane protein solubilization and stabilization. (2014) (28)
Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water. (2013) (27)
Mechanistic comparison of artificial-chaperone-assisted and unassisted refolding of urea-denatured carbonic anhydrase B. (1998) (27)
Cyclic constraints on conformational flexibility in γ-peptides: conformation specific IR and UV spectroscopy. (2013) (27)
Quantitative Analysis of Hydrophobically Induced Folding in a Minimal Model System (1997) (27)
Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. (2005) (27)
A Rapid 1H NMR Assay for Enantiomeric Excess of α-Substituted Aldehydes (2005) (27)
Bacterial species selective toxicity of two isomeric α/β-peptides: Role of membrane lipids (2005) (27)
Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. (2002) (27)
High-resolution structures of a heterochiral coiled coil (2015) (27)
Spectroscopic characterization of selected β- sheet hairpin models (2002) (26)
Diacid linkers that promote parallel beta-sheet secondary structure in water. (2008) (26)
Effects of backbone rigidification on intramolecular hydrogen bonding in a family of diamides (1993) (26)
Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity. (2019) (25)
Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. (2005) (25)
Irreversible Agonist-Beta2 Adrenoceptor Complex (2011) (25)
Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue. (2013) (24)
Lyotropic liquid crystalline phases from helical β-peptides as alignment media. (2011) (24)
Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution. (2016) (24)
Intramolecular hydrogen bonding in simple diamides (1989) (24)
Foldamer Catalysis. (2020) (24)
Residue-based control of helix shape in beta-peptide oligomers. (1997) (24)
Synthesis of beta-lactams bearing functionalized side chains from a readily available precursor. (2008) (23)
Highly stable pleated-sheet secondary structure in assemblies of amphiphilic alpha/beta-peptides at the air-water interface. (2010) (23)
Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. (2004) (23)
Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives (1992) (23)
Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. (2004) (23)
Role of ring-constrained γ-amino acid residues in α/γ-peptide folding: single-conformation UV and IR spectroscopy. (2013) (23)
Complexation of hexosammonium ions: evidence for contributions from OH.cntdot..cntdot..cntdot.OH hydrogen bonds in a hydroxylic medium (1993) (22)
Receptor selectivity from minimal backbone modification of a polypeptide agonist (2018) (22)
Establishing effective simulation protocols for beta- and alpha/beta-peptides. II. Molecular mechanical (MM) model for a cyclic beta-residue. (2008) (22)
Evaluation of the Conformation-Directing Effects of Secondary Hydrogen-Bonding Interactions in Flexible Tetrapeptide Analogs (1995) (21)
Thermodynamic Analysis of Autonomous Parallel β-Sheet Formation in Water (2006) (21)
Rational development of beta-peptide inhibitors of human cytomegalovirus entry. (2006) (21)
Incremental preorganization of a chelating macrocycle (1990) (21)
Impact of Strand Number on Parallel β-Sheet Stability. (2015) (21)
Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. (2004) (21)
Kinetics of Anionic Ring-Opening Polymerization of Variously Substituted β-Lactams: Homopolymerization and Copolymerization (2010) (21)
Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery (2014) (21)
Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure. (2013) (21)
Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. (2004) (20)
Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange. (2007) (20)
A Cationic Polymer That Shows High Antifungal Activity against Diverse Human Pathogens (2017) (20)
Molecular structure and conformation of two acyclic polythioethers: Implications for the design of heavy metal chelators (1990) (20)
Effects of Amphiphilic Topology on Self-Association in Solution, at the Air-Water Interface, and in the Solid State (1995) (20)
Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation. (2018) (20)
(R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. (2000) (20)
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation (2021) (20)
The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif. (2012) (19)
Antifungal activity from 14-helical beta-peptides. (2006) (19)
Sequence Dependent Behavior of Amphiphilic β-Peptides on Gold Surfaces (2007) (19)
Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist. (2016) (19)
Inhibition of Ice Recrystallization by Nylon-3 Polymers. (2017) (19)
Solution structure of a small protein containing a fluorinated side chain in the core (2006) (19)
A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. (2008) (19)
Mimicking the first turn of an α-helix with an unnatural backbone: conformation-specific IR and UV spectroscopy of cyclically constrained β/γ-peptides. (2014) (19)
Structural Characterization of Peptide Oligomers Containing (1R,2S)‐2‐Aminocyclohexanecarboxylic Acid (cis‐ACHC) (2013) (19)
Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers (2021) (19)
Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes (2015) (19)
Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization. (2013) (19)
Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis. (2016) (19)
Catalytic metathesis of simple secondary amides. (2007) (18)
Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. (2005) (18)
Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR (2020) (18)
New evidence that the hydrophobic effect and dispersion are not major driving forces for nucleotide base stacking. (1996) (18)
Impact of strand length on the stability of parallel-β-sheet secondary structure. (2011) (18)
SPECTROMICROSCOPY AT THE ORGANIC-INORGANIC INTERFACE IN BIOMINERALS (2005) (17)
Single-molecule force spectroscopy of β-peptides that display well-defined three-dimensional chemical patterns. (2011) (17)
Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. (2015) (17)
Optimization of a phosphine oxide disulfoxide array for multipoint hydrogen bonding to ammonium ions (1993) (17)
Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams. (2012) (17)
Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF (2017) (16)
Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum. (2011) (15)
Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor (2021) (15)
Effect of a C-Terminal Cationic Group on the Competition between .alpha.-Helical Turn and .beta.-Turn in a Model Depsipeptide (1994) (15)
Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. (2005) (15)
Conformation-specific spectroscopy of capped glutamine-containing peptides: role of a single glutamine residue on peptide backbone preferences. (2016) (15)
Improved treatment of cyclic β‐amino acids and successful prediction of β‐peptide secondary structure using a modified force field: AMBER*C (2000) (15)
Hydrogen bonding in a family of triamides: conformation-directing effects in solution versus the solid state (1990) (15)
Dipole-induced self-assembly of helical beta-peptides. (2008) (14)
Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. (2012) (14)
Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. (2004) (14)
Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution. (2017) (14)
Effects of amphiphile topology on aggregation properties : distinctive behavior of contrafacial amphiphiles (1993) (14)
An autonomously folding β‐hairpin derived from the human YAP65 WW domain: Attempts to define a minimum ligand‐binding motif (2005) (14)
Preparation of Protected syn-α,β-Dialkyl β-Amino Acids That Contain Polar Side Chain Functionality† (2003) (14)
Differential Effects of β3 - versus β2 -Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides. (2018) (14)
Helical secondary structures in 2:1 and 1:2 α/γ-peptide foldamers (2012) (14)
Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. (2019) (14)
Cationic Side Chain Identity Directs the Hydrophobically Driven Self-Assembly of Amphiphilic β-Peptides in Aqueous Solution. (2021) (13)
Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. (2003) (13)
Helix Propensities of Amino Acid Residues via Thioester Exchange. (2017) (13)
Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides. (2018) (13)
Crystallographic evidence for multiple coordinating conformations in a family of macrocyclic chelators (1991) (13)
On the use of AM1 calculations for the study of intramolecular hydrogen bonding phenomena in simple amides (1992) (13)
Thermodynamics of copper(II) complexation by macrocyclic tetrathioethers at 25.degree.C in water-methanol mixtures and acetonitrile: correlations of complexation enthalpy and ligand conformational preferences (1992) (13)
Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils. (2012) (13)
A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. (2019) (13)
Evaluation of β‐Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure (2018) (13)
Nickel(II) chelation by three bicyclic tetrathioethers : solution and solid-state data (1993) (13)
Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. (2005) (13)
Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. (2019) (12)
Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. (2003) (12)
Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. (2004) (12)
Incorporation of β-Amino Acids Enhances the Antifungal Activity and Selectivity of the Helical Antimicrobial Peptide Aurein 1.2. (2017) (11)
Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization, Stabilization and Crystallization (2013) (11)
Using Constrained β‐Amino Acid Residues to Control β‐Peptide Shape and Function (2005) (11)
Association of helical beta-peptides and their aggregation behavior from the potential of mean force in explicit solvent. (2009) (11)
Macrocycles containing sulfur and phosphorus: Structure and complexation properties (1993) (11)
Application of microwave irradiation to the synthesis of 14-helical beta-peptides. (2005) (11)
Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. (2012) (11)
Interaction of the Hydrophobic Tip of an Atomic Force Microscope with Oligopeptides Immobilized Using Short and Long Tethers. (2016) (11)
Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi (2018) (11)
Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase. (2016) (10)
Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. (2008) (10)
Molekulare Architektur mit funktionalisierten β‐Peptid‐Helices (2003) (10)
Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. (2002) (9)
Retention of Native Quaternary Structure in Racemic Melittin Crystals. (2019) (9)
An unusual hydrogen bonding pattern in a crystallographically observed β-turn (1992) (9)
Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. (2007) (9)
Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. (2019) (9)
Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. (2008) (9)
Thermodynamic Scale of β-Amino Acid Residue Propensities for an α-Helix-like Conformation. (2018) (8)
Strategies for Nonmacrocyclic Polythioether Ligands: New Pentacoordinating Architectures (1994) (8)
Crystallographic characterization of N-oxide tripod amphiphiles. (2010) (8)
Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability. (2021) (7)
Detection and Analysis of Chimeric Tertiary Structures by Backbone Thioester Exchange: Packing of an α Helix against an α / β -Peptide Helix ** (2010) (7)
Synthetic Studies on the 1,6-Methano[10]annulene Skeleton: A New Route That Provides Derivatives Substituted at the Bridge and on the Annulene Ring (1994) (7)
Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection (2021) (7)
Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion. (2014) (7)
Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids (2019) (6)
Molecular architecture with functionalized beta-peptide helices. (2003) (6)
New synthesis of methano-bridged annulenes: access to highly substituted derivatives (1992) (6)
Stereoselective oxidation of an eleven-membered heterocycle (1992) (6)
Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. (2019) (6)
Macrocyclic design strategies for small, stable parallel beta-sheet scaffolds. (2009) (6)
Secondary Effects in Flexible Hydrogen Bonding Networks (1997) (6)
STERIC CONTROL OF OXIDATION SELECTIVITY IN MACROCYCLIC PHOSPHINE OXIDE-DITHIOETHERS (1997) (6)
Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. (2013) (6)
Ammonolysis of anilides promoted by ethylene glycol and phosphoric acid (2014) (6)
Synthesis and Aggregation Properties of a New Family of Amphiphiles with an Unusual Headgroup Topology. (1992) (6)
Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum. (2021) (5)
Electrophile-induced Berson-Willcott rearrangement of 11-carboxyl-1,6-methano[10]annulene methyl ester (1994) (5)
Enantioselective Organocatalytic Aminomethylation of Aldehydes: A Role for Ionic Interactions and Efficient Access to β2-Amino Acids. (2006) (5)
Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of Clostridioides difficile. (2021) (5)
Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes. (2007) (5)
Stereospecific Synthesis of Conformationally Constrained γ‐Amino Acids: New Foldamer Building Blocks That Support Helical Secondary Structure. (2010) (5)
Lyotropic liquid crystals from designed helical beta-peptides. (2006) (5)
On the use of molecular mechanics calculations for the study of intramolecular hydrogen bonding phenomena (1991) (4)
Improved treatment of cyclic -amino acids and successful prediction of -peptide secondary structure using a modified force field: AMBER*C (2000) (4)
Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments [J. Am. Chem. Soc. 2000, 122, 3995−4004]. (2001) (4)
On the Hydrogen-Bonded Status of 2-Azacyclononanone and 2-Azacyclotridecanone in the Solid State (1994) (4)
Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Isoxazolidones. (2003) (4)
Backbone Modifications of HLA-A2-Restricted Antigens Induce Diverse Binding and T Cell Activation Outcomes. (2021) (4)
Use of a Stereochemical Strategy to Probe the Mechanism of Phenol-Soluble Modulin A3 Toxicity (2019) (3)
Mimicking the First Turn of an Alpha-Helix with an Unnatural Backbone: Conformation-Specific IR and UV Spectroscopy of Cyclically Constrained Beta/Gamma-Peptides (Dataset) (2014) (3)
Effects of single α-to-β residue replacements on recognition of an extended segment in a viral fusion protein. (2020) (3)
Toward a Soluble Model System for the Amyloid State. (2017) (3)
Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. (2006) (3)
Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy. (2020) (3)
Parallel sheet secondary structure in beta-peptides. (2003) (3)
Preparation of β2-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy. (2020) (3)
Model systems: This year's model (2002) (3)
Crystallographic characterization of the alpha/beta-peptide 14/15-helix. (2007) (3)
Foldamers. Structure, Properties, and Applications. Edited by Stefan Hecht and Ivan Huc. (2008) (2)
Functionalized Nitrogen Atom Transfer Catalyzed by Cytochrome P-450. (1986) (2)
Erratum: Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups (Journal of the American Chemical Society (2010) 132 (13879-13885)) (2010) (2)
Harnessing Noncovalent Interactions to Drive Single-Chain Nanoparticle Formation (2020) (2)
An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quaternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions (2009) (2)
Synthesis of 4,4‐Disubstituted 2‐Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12‐Helical β‐Peptides. (2005) (2)
Thermodynamic analysis of autonomous parallel beta-sheet formation in water. (2006) (2)
Role of Ring-Constrained Gamma-Amino Acid Residues in Alpha/Gamma-Peptide Folding: Single-Conformation UV and IR Spectroscopy (Dataset) (2015) (2)
Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water. (2013) (2)
Spectroscopic characterization of selected beta- sheet hairpin models. (2002) (2)
Influence of immobilized cations on the thermodynamic signature of hydrophobic interactions at chemically heterogeneous surfaces (2020) (2)
Catalytic Intramolecular Conjugate Additions of Aldehyde-Derived Enamines to α,β-Unsaturated Esters. (2020) (2)
Thermodynamic stability of beta-peptide helices and the role of cyclic residues. (2006) (2)
Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents. (2021) (2)
Impact of Substitution Registry on the Receptor‐Activation Profiles of Backbone‐Modified Glucagon‐like Peptide‐1 Analogues (2019) (2)
Comparisons of β‐Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands (2021) (2)
New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns. (2006) (2)
Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. (2003) (2)
Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold. (2022) (2)
NINETEEN a-Helix Mimicry with a / b-Peptides (2013) (1)
Kinetic and Thermodynamic Insights on Agonist Interactions with the Parathyroid Hormone Receptor-1 from a New NanoBRET assay (2022) (1)
Erratum: Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study (Chemical Communications (2013) 49 (2287-2289) DOI: 10.1039/c2cc36844g) (2013) (1)
Diverse Impacts on Prokaryotic and Eukaryotic Membrane Activities from Hydrophobic Subunit Variation Among Nylon-3 Copolymers. (2020) (1)
Preparation of Protected syn‐α,β‐Dialkyl β‐Amino Acids that Contain Polar Side Chain Functionality. (2003) (1)
Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods (2023) (1)
Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling. (2022) (1)
Enantioselective Organocatalytic Aminomethylation of Aldehydes (2006) (1)
A rapid 1H NMR assay for enantiomeric excess of alpha-substituted aldehydes. (2005) (1)
Potential Foldamers Based on an ortho-Terphenyl Amino Acid. (2021) (1)
Solution structure of a small protein containing a fluorinated side chain in the core. (2007) (1)
Erratum: A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane protein (Chemistry - A European Journal (2012) 31) (2013) (1)
Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence. (2005) (1)
Formation of versus Recruitment to RNA-Rich Condensates: Controlling Effects Exerted by Peptide Side Chain Identity. (2022) (1)
Correction to Synthesis of β-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor (2014) (1)
Single-cell, Time-resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live E. coli (2016) (1)
Synthetic Studies on the 1,6-Methano(10)annulene Skeleton: A New Route that Provides Derivatives Substituted at the Bridge and on the Annulene Ring. (1995) (1)
Effects of Backbone Rigidification on Intramolecular Hydrogen Bonding in a Family of Diamides. (1993) (1)
Erratum: An improved tripod amphiphile for membrane protein solubilization (Protein Science (2000) 9 (2518-2527)) (2001) (1)
An Efficient Route to Either Enantiomer of Orthogonally Protected trans-3-Aminopyrrolidine-4-carboxylic Acid (V). (2001) (1)
What Vesicle Leakage Reveals about Antimicrobial Activity (and What It Doesn't) (2015) (1)
Local Rigidification and Possible Coacervation of the E. coli DNA by Cationic Nylon-3 Polymers. (2021) (1)
Characterization of Hydrophobic Interactions of SARS-CoV-2 and MERS-CoV Spike Protein Fusion Peptides Using Single Molecule Force Measurements (2022) (1)
Corrigendum to “Influence of Strand Number on Antiparallel β-Sheet Stability in Designed Three- and Four-Stranded β-Sheets” (2003) (1)
Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with HH4, an alpha/beta-Peptide with Irregular Secondary Structure (2019) (0)
Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution (2018) (0)
Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VI (2019) (0)
Gas-Phase Folding of Small Glutamine Containing Peptides: Sidechain Hydrogen Bonding Stabilizes $\beta $-turns. (2017) (0)
Solution structure of chicken villin headpiece subdomain containing a fluorinated side chain in the core (2006) (0)
Zr(NMe2)4-Catalyzed Transamidationand Amide Metathesis Reactions (2009) (0)
CONFORMATION-SPECIFIC SPECTROSCOPY OF A PROTOTYPICAL $\gamma$-PEPTIDE-WATER COMPLEX: Ac-$\gamma$$^{2}$-hPhe-NHMe-(H$_{2}$O)$_{1}$ (2010) (0)
Crystal Structure of Vascular Endothelial Growth Factor (VEGF8-109) with one copy of HH4, an alpha/beta-Peptide with Irregular Secondary Structure (2020) (0)
Conformation-Specific Infrared Spectroscopy of γ 2 -PEPTIDE Foldamers: Ac-γ 2 -hPhe-γ 2 -hAla-NHMe and Ac-γ 2 -hAla-γ 2 -hPhe-NHMe (2010) (0)
Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 13 (2015) (0)
Complex of 4-alpha/beta bound to gp41-5 (2012) (0)
FUNCTIONALIZED BETA-LACTAM $ 93 . d } A 2 . ES SNR , et MONOMERS AND ANTIBACTERIAL ESA RE SERC COMPOSITIONS CONTAINING SAME 60 13758 A i / 2000 (2017) (0)
Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL (2011) (0)
alpha/beta foldamer in complex with Bcl-xL (2009) (0)
A chimeric alpha+alpha/beta peptide based on the CHR domain sequence of gp41 (2011) (0)
Effect of p-peptide inhibitors 10 um on HCMV Infection of NHDF (2017) (0)
Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 (2011) (0)
Toward design of a triple stranded antiparallel β-sheet (2002) (0)
Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid (2013) (0)
Corrections (2011) (0)
Respiratory syncytial virus fusion protein N-terminal heptad repeat domain+VIQKI (2019) (0)
Assembly of VIQKI D455(beta-L-homoaspartic acid)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
Structure of Pin1 WW Domain Variant 1 with beta3-Ser Loop Substitution (2018) (0)
Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly (2020) (0)
Exploring backbone pattern in alpha/beta-peptide helix bundles: The GCN4-pLI side chain sequence on different (alpha-alpha-alpha-beta) backbones (2009) (0)
Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. (2003) (0)
Bcl-2 alpha beta-1 complex (2015) (0)
Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo. (2022) (0)
Racemic Phenol-Soluble Modulin Alpha 3 Peptide (2019) (0)
A New Synthesis of Methano-Bridged Annulenes: Access to Highly Substituted Derivatives. (1992) (0)
Inside Cover: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins (Chem. Eur. J. 31/2012) (2012) (0)
Electrophile-Induced Berson-Willcott Rearrangement of 11-Carboxyl-1,6- methano(10)annulene Methyl Ester. (1994) (0)
FOLDAMERS, CROWNS, AND WATER: CONNECTIONS BETWEEN ISOLATED MOLECULES AND SOLUTION-PHASE BEHAVIOR (2010) (0)
United States Patent (2006) (0)
Complex of 3-alpha bound to gp41-5 (2012) (0)
Corrigendum: Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane‐Protein Superassembly: Importance of Branching in the Hydrophilic Portion (0)
(Z)-2-(Benzoyl-aci-nitro)-2-phenylacetonitrile (1996) (0)
CONFORMATION-SPECIFIC AND MASS-RESOLVED, INFRARED-POPULATION TRANSFER SPECTROSCOPY OF THE MODEL $\gamma^{2}$-PEPTIDE Ac-$\gamma$$^{2}$-hPhe-NHMe: EVIDENCE FOR THE PRESENCE OF INTRAMOLECULAR AMIDE-AMIDE STACKING INTERACTIONS. (2009) (0)
Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2‐Amino Acids. (2008) (0)
Cover Picture: Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design (ChemBioChem 13/2011) (2011) (0)
In vitro and in vivo Inhibition of Herpes Simplex Virus Infection by Cationic Beta-Peptides (2008) (0)
Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions. (2007) (0)
Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI I454F I456F (2020) (0)
Vascular endothelial growth factor in complex with alpha/beta-VEGF-1 (2015) (0)
Puma BH3 foldamer in complex with Bcl-xL (2011) (0)
MINIMIZED AVERAGE STRUCTURE OF DP-TT2 (2001) (0)
NMR structure for a 2-stranded parallel beta-sheet (2015) (0)
Crystal structure of alpha-beta foldamer 4c in complex with Bcl-xL (2011) (0)
HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide (2009) (0)
Structure and function in beta-peptide foldamers (2001) (0)
SPECTROSCOPIC INVESTIGATION OF $\alpha$/$\beta$-PEPTIDES Ac-Phe-ACPC-NHMe AND Ac-ACPC-Phe-NHMe (2007) (0)
Respiratory syncytial virus fusion glycoprotein N-terminal heptad repeat domain+VIQKI I456F (2020) (0)
No . 1 Stereoselective Oxidation of an Eleven-Membered Heterocycle by (0)
Assembly of VIQKI P5(beta-L-homoproline) with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
Racemic M2-TM I39A crystallized from racemic detergent (2019) (0)
Correction 174, p. 1047 (2006) (0)
alpha/beta-Peptide helix crystallized from detergent solution: GCN4-pLI side chain sequence on an (alpha-alpha-beta-alpha-beta-alpha-beta) backbone with cyclic beta-residues (2009) (0)
Co-assembly of VIQKI D452(beta-L-homoaspartic acid) with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
CONFORMATION SPECIFIC SPECTROSCOPIC INVESTIGATION OF $\beta$- and $\alpha$/$\beta$-PEPTIDES: INSIGHT INTO THE AMIDE I AND AMIDE II SPECTRAL SIGNATURES (2008) (0)
HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence (2009) (0)
α/γ‐ペプチドのヘリックス構造形成におけるコンフォメーション制御されたγ‐アミノ酸ユニットの役割 (2013) (0)
Villin headpiece subdomain with a Gln26 to beta-3-homoglutamine substitution (2016) (0)
Analysis of Piscidin and Lipopolysaccharide Interactions: A Step Towards Characterizing Immunomodulation (2015) (0)
Bcl-2 alpha beta-1 LINEAR complex (2015) (0)
Racemic melittin (2019) (0)
Villin headpiece subdomain with a Lys30 to beta-3-homolysine substitution (2016) (0)
Structure of racemic Ala-(8,13,18) Magainin 2 (2013) (0)
HIV gp41 six-helix bundle composed of an alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide (2009) (0)
Racemic influenza M2-TM crystallized from monoolein lipidic cubic phase (2015) (0)
alpha/beta-Peptide helix bundles: The GCN4-pLI side chain sequence on an (alpha-alpha-alpha-beta) backbone (2008) (0)
Correction to “Crystallographic Characterization of N-Oxide Tripod Amphiphiles” (2013) (0)
Bcl-xL bound to alpha beta Puma BH3 peptide 5 (2014) (0)
Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI (2019) (0)
NMR structure for a 3-stranded parallel beta-sheet (2015) (0)
Correction to "Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold". (2022) (0)
The Inherent Conformational Preferences of Glutamine-Containing Peptides: the Role for Side-Chain Backbone Hydrogen Bonds (2015) (0)
Stereoselective Oxidation of an Eleven-Membered Heterocycle. (1992) (0)
alpha/beta-Peptide helix bundles: A GCN4-pLI analogue with an (alpha-alpha-beta) backbone and cyclic beta residues (2008) (0)
Crystal structure of racemic villin headpiece subdomain crystallized in space group P-1 (2012) (0)
Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC (2018) (0)
Crystal structure of racemic villin headpiece subdomain in space group I-4c2 (2012) (0)
SINGLE-CONFORMATION SPECTROSCOPIC INVESTIGATION OF PEPTIDE BUILDING BLOCKS IN THE AMIDE I SPECTRAL REGION: COMPARISON OF EXPERIMENT TO DENSITY FUNCTIONAL THEORY AND THE TRANSITION DIPOLE COUPLING MODEL (2010) (0)
Ammonolysis of Anilides Promoted by Ethylene Glycol and Phosphoric Acid. (2015) (0)
Membrane Leakage and Antimicrobial Action of Polymers and Surfactants (2014) (0)
Steric Control of Oxidation Selectivity in Macrocyclic Phosphine Oxide‐Dithioethers. (1998) (0)
Villin headpiece subdomain with a Gln26 to ACPC substitution (2016) (0)
Novel Pentacoordinating Polythioether Ligands - An Alternative to Macrocyclic Chelate Ligands. (1994) (0)
Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to a gp41 NHR domain peptide (2011) (0)
An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quarternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions - higher symmetry crystal (2009) (0)
Assembly of VIQKI I456(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
Correction to “Tandem Facial Amphiphiles for Membrane Protein Stabilization” (2013) (0)
CONFORMATION AND DIASTEREOMERIC SPECIFIC SPECTROSCOPIC INVESTIGATION OF $\alpha$/$\beta$-PEPTIDES Ac-Phe-$\beta$$^{3}$-hAla-NHMe AND Ac-$\beta$$^{3}$-hAla-Phe-NHMe (2008) (0)
Incremental Preorganization of a Chelating Macrocycle. (1990) (0)
Crystal Structure of Quasiracemic Villin Headpiece Subdomain Containing (F5Phe10) Substitution (2012) (0)
Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate (2013) (0)
Cyclic residues in alpha/beta-peptide helix bundles: GCN4-pLI side chain sequence on an (alpha-alpha-beta) backbone with cyclic beta-residues at positions 1, 4, 10, 19 and 28 (2010) (0)
Crystal structure of quasiracemic villin headpiece subdomain containing (F5Phe17) substitution (2012) (0)
CONFORMATION-SPECIFIC UV and IR SPECTROSCOPY OF CONFORMATIONALLY CONSTRAINED $\alpha$/$\gamma$ PEPTIDE FOLDAMERS (2013) (0)
SPECTROSCOPIC INVESTIGATION OF $\beta$-PEPTIDES: Ac-$\beta$$^3$-Phe-NHMe, Ac-$\beta$$^3$-Phe-$\beta$$^3$-Ala-NHMe AND Ac-$\beta$$^3$-Ala-$\beta$$^3$-Phe-NHMe (2007) (0)
Location Bias in cAMP Signaling and its effects on Parathyroid Hormone Receptor Biological Effectiveness (2021) (0)
Assembly of VIQKI I454(beta-L-homoisoleucine)with human parainfluenza virus type 3 (HPIV3) fusion glycoprotein N-terminal heptad repeat domain (2020) (0)
Human parainfluenza virus type 3 fusion glycoprotein N-terminal heptad repeat domain+alpha/beta-VI (2021) (0)
Access to γ2-Amino Acids (2008) (0)
Synthesis and Structural Characterization of Helix‐Forming β‐Peptides: trans‐2‐Aminocyclopentanecarboxylic Acid Oligomers. (1999) (0)
Trimeric helix bundle formed by an alpha/beta-peptide derivative of the HIV gp41 CHR domain (2009) (0)
CONFORMATION-SPECIFIC INFRARED SPECTROSCOPY OF $\gamma^{2}$-PEPTIDE FOLDAMERS: Ac-$\gamma^{2}$-hPhe-$\gamma^{2}$-hAla-NHMe AND Ac-$\gamma^{2}$-hAla-$\gamma^{2}$-hPhe-NHMe (2010) (0)
Complex of an alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 (2011) (0)
Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 (2011) (0)
An Improved Tripod Amphiphile for Membrane Protein Solubilization (2001) (0)

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What Schools Are Affiliated With Samuel h. Gellman?

Samuel h. Gellman is affiliated with the following schools:

University of Bristol
University of Michigan
McMaster University
University of Wisconsin–Madison
University of South Florida
Rockefeller University
Georgetown University
Purdue University
University of Massachusetts Medical School
University of Pittsburgh
Duke University
Seoul National University