Samuel Santoro

Q: What Schools Are Affiliated With Samuel Santoro

Samuel Santoro is affiliated with the following schools: Washington University in St. Louis, University of California, Berkeley, Vanderbilt University, Stanford University

Samuel Santoro's AcademicInfluence.com Rankings

Samuel Santoro

Biology

#4986

World Rank

#7352

Historical Rank

Immunology

#687

World Rank

#709

Historical Rank

Microbiology

#683

World Rank

#755

Historical Rank

biology Degrees

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Biology

Samuel Santoro's Degrees

Bachelors Microbiology University of California, Berkeley
PhD Immunology Stanford University

Why Is Samuel Santoro Influential?

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According to Wikipedia, Samuel A. Santoro is an American microbiologist and immunologist, focusing in structure and biology of integrin adhesive receptors for extracellular matrix proteins, currently the Dorothy B. and Theodore R. Austin Professor and Chair at Vanderbilt University.

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Samuel Santoro's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance. (1990) (1115)
Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen (1986) (393)
The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++- dependent adhesion of platelets to collagen (1989) (389)
Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen. (1991) (344)
The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis. (2002) (285)
Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin. (1985) (262)
The impact of heparin concentration and activated clotting time monitoring on blood conservation. A prospective, randomized evaluation in patients undergoing cardiac operation. (1995) (257)
Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast. (1990) (252)
Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells. (1995) (241)
Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells. (1995) (226)
Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen* (2001) (214)
Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation. (1994) (210)
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin (2004) (207)
Decorin Binds Near the C Terminus of Type I Collagen* (2000) (196)
Tumor cell α3β1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis (2004) (193)
Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-Xa heparin concentration in patients having cardiac operations. (1994) (185)
The α2β1 Integrin: A Collagen Receptor on Platelets and other Cells (1995) (180)
Inhibition of neointimal hyperplasia by blocking αvβ3 integrin with a small peptide antagonist GpenGRGDSPCA (1994) (180)
More Effective Suppression of Hemostatic System Activation in Patients Undergoing Cardiac Surgery by Heparin Dosing Based on Heparin Blood Concentrations rather than ACT (1996) (179)
Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor. (1990) (177)
The platelet glycoprotein thrombospondin binds specifically to sulfated glycolipids. (1985) (169)
Isolation and characterization of a heparin-binding domain from the amino terminus of platelet thrombospondin. (1984) (153)
A monoclonal antibody against human thrombospondin inhibits platelet aggregation. (1985) (153)
Isolation and characterization of a platelet surface collagen binding complex related to VLA-2. (1988) (152)
GPVI and α2β1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow (2005) (151)
Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins (1987) (142)
Activated platelets express IL-1 activity. (1989) (134)
β1 Integrin Mediates Internalization of Mammalian Reovirus (2006) (134)
The alpha 2 beta 1 integrin cell surface collagen receptor binds to the alpha 1 (I)-CB3 peptide of collagen. (1990) (121)
Loss of MDCK cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis. (1995) (121)
A Three-dimensional Collagen Lattice Activates NF-κB in Human Fibroblasts: Role in Integrin α2 Gene Expression and Tissue Remodeling (1998) (118)
The human alpha 2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression. (1994) (116)
The contributions of the α2β1 integrin to vascular thrombosis in vivo (2003) (113)
Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization. (1993) (110)
ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. (1997) (105)
Distinct determinants on collagen support alpha 2 beta 1 integrin-mediated platelet adhesion and platelet activation. (1991) (102)
Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing (1985) (101)
The spatial and temporal expression of the α2β1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis (1995) (101)
Interactions of exercise, coagulation, platelets, and fibrinolysis--a brief review. (1988) (99)
Determinants of Ligand Binding Specificity of the α1β1 and α2β1Integrins* (1999) (95)
Ligand recognition by the I domain-containing integrins (1998) (94)
Beta1 integrin mediates internalization of mammalian reovirus. (2006) (89)
Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells. (1991) (87)
Evaluation of a New Point-of-care Test that Measures PAF-mediated Acceleration of Coagulation in Cardiac Surgical Patients (1996) (87)
α2 Integrin Subunit Cytoplasmic Domain-dependent Cellular Migration Requires p38 MAPK* (2001) (87)
Complex patterns of expression suggest extensive roles for the α2β1 integrin in murine development (1994) (86)
Contributions of the I and EF Hand Domains to the Divalent Cation-dependent Collagen Binding Activity of the α2β1 Integrin* (1997) (85)
Novel collectin/C1q receptor mediates mast cell activation and innate immunity. (2006) (83)
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin (2004) (82)
Fibronectin and the multiple interaction model for platelet-collagen adhesion. (1979) (79)
Structural Analysis of the α2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) Interaction* (2001) (77)
GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. (2005) (71)
Specific Residues within the α2 Integrin Subunit Cytoplasmic Domain Regulate Migration and Cell Cycle Progression via Distinct MAPK Pathways* (2001) (65)
Adsorption of von Willebrand factor/factor VIII by the genetically distinct interstitial collagens. (1981) (64)
Wound Healing in the α2β1 Integrin-Deficient Mouse: Altered Keratinocyte Biology and Dysregulated Matrix Metalloproteinase Expression (2007) (63)
Collagen-induced release of interleukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the alpha 5 beta 1 integrin. (1992) (62)
Collagen receptor control of epithelial morphogenesis and cell cycle progression. (1999) (59)
The contributions of the alpha 2 beta 1 integrin to vascular thrombosis in vivo. (2003) (58)
Inhibition of neointimal hyperplasia by blocking alpha V beta 3 integrin with a small peptide antagonist GpenGRGDSPCA. (1994) (58)
Induced cell surface expression of functional α2β1 integrin during megakaryocytic differentiation of K562 leukemic cells (1992) (57)
On‐site Prothrombin Time, Activated Partial Thromboplastin Time, and Platelet Count A Comparison between Whole Blood and Laboratory Assays with Coagulation Factor Analysis in Patients Presenting for Cardiac Surgery (1994) (56)
Preferential binding of high molecular weight forms of von Willebrand factor to fibrillar collagen. (1983) (56)
The spatial and temporal expression of the alpha 2 beta 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis. (1995) (54)
Transcriptional regulation of alpha IIb integrin gene expression during megakaryocytic differentiation of K562 cells. Role of a silencer element. (1994) (52)
Relative Importance of Thrombin Compared With Plasmin‐Mediated Platelet Activation in Response to Plasminogen Activation With Streptokinase (1991) (52)
Altered Integrin Expression and the Malignant Phenotype: The Contribution of Multiple Integrated Integrin Receptors (1998) (51)
Collagen-mediated platelet aggregation. Evidence for multivalent interactions of intermediate specificity between collagen and platelets. (1977) (50)
Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin. (1985) (50)
The alpha 2 beta 1 integrin: a collagen receptor on platelets and other cells. (1995) (50)
Extracellular chloride signals collagen IV network assembly during basement membrane formation (2016) (50)
Adsorption of von Willebrand factor by fibrillar collagen--implications concerning the adhesion of platelets to collagen. (1982) (49)
Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms [editorial; comment] (1994) (46)
In vitro reversal of heparin effect with heparinase: evaluation with whole blood prothrombin time and activated partial thromboplastin time in cardiac surgical patients. (1994) (46)
Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin. (1985) (45)
PDGF induction of alpha 2 integrin gene expression is mediated by protein kinase C-zeta (1996) (45)
Differential expression of integrin α subunits supports distinct roles during lung branching morphogenesis (1996) (45)
Monitoring activity of fibrinolytic agents. A therapeutic challenge. (1984) (42)
Differential regulation of the alpha 2 beta 1 and alpha IIb beta 3 integrin genes during megakaryocytic differentiation of pluripotential K562 cells. (1992) (42)
Platelet surface collagen receptor polymorphisms: variable receptor expression and thrombotic/hemorrhagic risk. (1999) (42)
Localization of the hemagglutinating activity of platelet thrombospondin to a 140 000-dalton thermolytic fragment. (1984) (41)
Inhibition of platelet aggregation by fibronectin. (1983) (41)
[8] Analysis of collagen receptors (1994) (40)
Isolation of the fibrinogen-binding region of platelet thrombospondin. (1984) (40)
Whole blood heparin concentration measurements by automated protamine titration agree with plasma anti-Xa measurements. (1997) (39)
Parathyroid Cells Cultured in Collagen Matrix Retain Calcium Responsiveness: Importance of Three‐Dimensional Tissue Architecture (2004) (35)
Mammary Epithelial Cell-Cycle Progression via the α2β1 Integrin : Unique and Synergistic Roles of the α2 Cytoplasmic Domain (2001) (34)
The nature of interactions between tissue-type plasminogen activator and platelets. (1990) (34)
&agr;2&bgr;1 Integrin and Development of Atherosclerosis in a Mouse Model: Assessment of Risk (2003) (33)
α2β1 Integrin. (2014) (33)
Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression. (2007) (32)
Downstream Events in Mammary Gland Morphogenesis Mediated by Reexpression of the α2β1 Integrin: The Role of the α6 and β4 Integrin Subunits (1998) (31)
Molecular basis of platelet adhesion to collagen. (1988) (31)
Ligand binding results in divalent cation displacement from the alpha 2 beta 1 integrin I domain: evidence from terbium luminescence spectroscopy. (1998) (31)
The α2 Integrin Subunit-Deficient Mouse (2002) (30)
Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. (1994) (29)
Integrins and the kidney: biology and pathobiology. (1999) (28)
Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms. (1994) (28)
Effect of aprotinin on activated clotting time, whole blood and plasma heparin measurements. (1995) (27)
Collagen-Mediated Platelet Aggregation: The Role of Multiple Interactions between the Platelet Surface and Collagen (1980) (26)
Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis. (1996) (25)
Effects of platelets and white blood cells and antiplatelet agent C7E3 (Reopro) on a new test of PAF procoagulant activity of whole blood. (1997) (25)
Negative regulation of activated alpha-2 integrins during thrombopoiesis. (2009) (25)
Enhancing Integrin α1 Inserted (I) Domain Affinity to Ligand Potentiates Integrin α1β1-mediated Down-regulation of Collagen Synthesis* (2012) (24)
Effect of heparin on whole blood activated partial thromboplastin time using a portable, whole blood coagulation monitor. (1995) (24)
Determinants of ligand binding specificity of the alpha(1)beta(1) and alpha(2)beta(1) integrins. (1999) (24)
Optimizing personalized bone marrow testing using an evidence-based, interdisciplinary team approach. (2013) (23)
[24] Isolation and characterization of thrombospondin (1987) (22)
Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by complex gangliosides. (1989) (22)
Mammary epithelial cell-cycle progression via the alpha(2)beta(1) integrin: unique and synergistic roles of the alpha(2) cytoplasmic domain. (2001) (22)
Dependence of plasmin-mediated degradation of platelet adhesive receptors on temperature and Ca2+. (1990) (22)
α2β1 Integrin, GPVI Receptor, and Common FcRγ Chain on Mouse Platelets Mediate Distinct Responses to Collagen in Models of Thrombosis (2014) (22)
Analysis of collagen receptors. (1994) (22)
Suboptimal Activation of Protease-activated Receptors Enhances α2β1 Integrin-mediated Platelet Adhesion to Collagen* (2009) (21)
Distinct determinants on collagen support a2,1 integrin-mediated platelet adhesion and platelet activation (19)
New RGD analogue inhibits human platelet adhesion and aggregation and eliminates platelet deposition on canine vascular grafts. (1992) (19)
Characterization of the platelet agglutinating activity of thrombospondin. (1985) (19)
Multiple episodes of thrombosis with biventricular support devices with inadequate anticoagulation and evidence of accelerated intravascular coagulation. (1997) (18)
Differential effects of concanavalin A and succinyl concanavalin A on the macromolecular events of platelet activation. (1983) (18)
Induced cell surface expression of functional alpha 2 beta 1 integrin during megakaryocytic differentiation of K562 leukemic cells. (1992) (17)
Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity (2012) (17)
Collagen-Mediated Platelet Aggregation (1977) (17)
Binding of the alpha 2 integrin I domain to extracellular matrix ligands: structural and mechanistic differences between collagen and laminin binding. (1998) (16)
Evaluation of complete blood count results from a new, on-site hemocytometer compared with a laboratory-based hemocytometer. (1996) (16)
Alpha2beta1 integrin and development of atherosclerosis in a mouse model: assessment of risk. (2003) (15)
The effects of hemodialysis on platelet activation with new and reprocessed regenerated cellulose dialyzers. (1996) (15)
Divalent cation-dependent structure in the platelet membrane glycoprotein Ia-IIa (VLA-2) complex. (1990) (15)
The MD/PhD pathway to a career in laboratory medicine. (2007) (14)
Effects of antiplatelet drugs on dialysis-associated platelet deposition in polytetrafluoroethylene grafts. (1997) (14)
Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits. (1998) (13)
The effects of hemodialysis on platelet deposition in prosthetic graft fistulas. (1995) (12)
Alpha2beta1 integrin recognition of the carboxyl-terminal propeptide of type I procollagen: integrin recognition and feed-back regulation of matrix biosynthesis are mediated by distinct sequences. (1998) (11)
Thrombospondin and the adhesive behavior of platelets. (1987) (11)
Integrin Mediates Internalization of Mammalian Reovirus (2006) (11)
Role of the α1 and α2 Integrin Cytoplasmic Domains in Cell Morphology, Motility and Responsiveness to Stimulation by the Protein Kinase C Pathway (2000) (11)
Isolation and characterization of thrombospondin. (1987) (10)
Echoviruses 1 and 8 are closely related genetically, and bind to similar determinants within the VLA-2 I domain. (2001) (10)
Extracellular FGF-1 Inhibits Cytoskeletal Organization and Promotes Fibroblast Motility (2000) (10)
Platelet interactions with the vessel wall and prosthetic grafts (1993) (10)
Platelet-collagen adhesion-membrane fluidity and the development of high affinity adhesion through multiple interacting sites. (1981) (10)
adhesion and aggregate formation to collagen under flow GPVI and { alpha } 2 { beta } 1 play independent critical roles during platelet (2005) (9)
[25] Platelet — collagen adhesion (1982) (9)
The Ups and Downs of α2β1-Integrin Expression: Contributions to Epithelial Cell Differentiation and the Malignant Phenotype (1998) (8)
Platelet interactions with fibronectin: divalent cation-independent platelet adhesion to the gelatin-binding domain of fibronectin (1993) (7)
The dualistic mechanisms of platelet adhesion to von Willebrand factor substrates. (1987) (6)
Thrombin enhanced adhesion of platelets to von Willebrand factor substrates. (1986) (6)
Platelet interactions with fibronectin: divalent cation-independent platelet adhesion to the gelatin-binding domain of fibronectin. (1993) (6)
Mechanisms of vascular graft thrombosis: role of altered canine platelet sensitivity to thromboxane. (1989) (6)
Platelet-collagen adhesion. (1982) (5)
The α2ß1 integrin binds to the CB4 peptide of the α2(I) collagen chain (1997) (4)
Amino group modification inhibits ristocetin cofactor activity of human von Willebrand factor. (1982) (4)
Mechanism of inhibition by trinitrophenylation of the ristocetin cofactor activity of von Willebrand factor. (1984) (4)
Role of the alpha1 and alpha2 integrin cytoplasmic domains in cell morphology, motility and responsiveness to stimulation by the protein kinase C pathway. (2000) (4)
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through (cid:1) 2 (cid:2) 1 integrin (2004) (3)
PDGF Induction of oL 2 Integrin Gene Expression Is Mediated by Protein Kinase (1996) (3)
Platelets: platelet immunobiology. (1989) (2)
Duplicate coagulation assays warranted. (1985) (2)
The ups and downs of alpha 2 beta 1-integrin expression: contributions to epithelial cell differentiation and the malignant phenotype. (1998) (2)
Preparation of soluble peptide libraries: application to studies of platelet adhesion sequences. (1992) (1)
cell-binding domain of fibronectin Willebrand factor substrates by a synthetic tetrapeptide derived from the Inhibition of platelet adhesion to fibronectin, fibrinogen, and von (2011) (1)
Tumor cell (cid:1) 3 (cid:2) 1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis (2004) (1)
5120830 Inhibitory peptides against alpha-2, beta-1 mediated MG++ dependent adhesion of platelets to collagen (1993) (1)
Modulation of an RGDS binding site on the platelet membrane glycoprotein IIb-IIIa complex. (1989) (1)
Assessment of interference by heparin cofactor II in the DuPont aca antithrombin-III assay. (1988) (1)
The alpha 2 beta 1 integrin binds to the CB4 peptide of the alpha 2(I) collagen chain. (1997) (1)
The α2ß1 Integrin: Structure, Function, and Regulation of a Platelet Surface Collagen Receptor (1997) (1)
Transduction of mutated or wild type beta-catenin in a naturally beta-catenin nullosomic tumor cell line leads to elevated S100A4/mts-1/metastasin expression (2004) (0)
Comparison of ACT and Whole Blood Heparin Measurements to Laboratory Plasma Anti-XA Heparin Concentration in Cardiac Surgery PatientsG (1994) (0)
Affinity modulation of the α2 integrin I domain (2006) (0)
Re-expression of the 02131 integrin abrogates the malignant phenotype of breast carcinoma cells (2005) (0)
THE c~2(~ 1 INTEGRIN BINDS TO THE CB4 PEgFIDE OFTHE ct2(l) COI~I.AGEN CHAIN. (1997) (0)
Effect of Aprotinin on Whole Blood and Plasma, Anti-XA Heparin Concentration Measurements in Cardiac Surgery Patients (1994) (0)
Mapping Functional Domains of Human Platelet Thrombospondin with Electro-Blotting and High Sensitivity Sequencing (1987) (0)
Cell-surface Collagen Receptor (2007) (0)
[96] THE ROLE OF CYTOKINES IN LEFT VENTRICULAR REMODELING AFTER MYOCARDIAL INFARCTION (2009) (0)
Location, location, location: targeting the endothelium (2003) (0)
1 integrin to vascular thrombosis in vivo β 2 α The contributions of the (2013) (0)
Activation of integrin alpha-2 expression in human dermal fibroblasts by PDGF and PMA (1995) (0)
GPVI and (cid:1) 2 (cid:2) 1 play independent critical roles during platelet adhesion and aggregate formation to collagen under ﬂow (2005) (0)
Activated partial thromboplastin time response to varying, in vitro heparin concentrations: A comparison between a laboratory and a portable method (1994) (0)
Primary hemostasis (collagen-platelet interaction): introduction. (1978) (0)
Evidence-Based, Patient-Specific Guidelines Provide Efficient and Cost-Effective Molecular and Cytogenetic Testing in Hematologic Malignancy (2011) (0)
Differential effects of concanavalin a and succinyl concanavalin a on the process of platelet activation (1983) (0)

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Published Works

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What Schools Are Affiliated With Samuel Santoro?

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