Samuel Singer
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Computer Science
Samuel Singer's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science Stanford University
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(Suggest an Edit or Addition)Samuel Singer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. (2002) (4091)
- The landscape of somatic copy-number alteration across human cancers (2010) (3297)
- PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors (2003) (2321)
- Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. (2003) (2202)
- Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
- Differentiation and reversal of malignant changes in colon cancer through PPARγ (1998) (1071)
- KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. (2001) (988)
- Terminal differentiation of human breast cancer through PPAR gamma. (1998) (900)
- Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation (2005) (774)
- STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications (2001) (696)
- Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. (1997) (691)
- Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy (2010) (653)
- KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. (2000) (650)
- Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing (2013) (617)
- Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas (2017) (577)
- Soft tissue sarcomas of adults: state of the translational science. (2003) (559)
- Histologic Subtype and Margin of Resection Predict Pattern of Recurrence and Survival for Retroperitoneal Liposarcoma (2003) (550)
- Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. (1999) (519)
- Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
- Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST) (2008) (478)
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
- Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors. (2002) (446)
- Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. (2009) (443)
- PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors (2014) (420)
- A novel WWTR1‐CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites (2011) (411)
- PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis. (2002) (397)
- Subtype Specific Prognostic Nomogram for Patients With Primary Liposarcoma of the Retroperitoneum, Extremity, or Trunk (2006) (360)
- Novel V600E BRAF mutations in imatinib‐naive and imatinib‐resistant gastrointestinal stromal tumors (2008) (353)
- Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma. (2013) (348)
- Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs) (2004) (332)
- Advances in sarcoma genomics and new therapeutic targets (2011) (312)
- Results of Tyrosine Kinase Inhibitor Therapy Followed by Surgical Resection for Metastatic Gastrointestinal Stromal Tumor (2007) (296)
- High prevalence of CIC fusion with double‐homeobox (DUX4) transcription factors in EWSR1‐negative undifferentiated small blue round cell sarcomas (2012) (292)
- Lessons Learned From the Study of 10,000 Patients With Soft Tissue Sarcoma (2014) (285)
- Consistent MYC and FLT4 gene amplification in radiation‐induced angiosarcoma but not in other radiation‐associated atypical vascular lesions (2011) (278)
- Identification of a novel, recurrent HEY1‐NCOA2 fusion in mesenchymal chondrosarcoma based on a genome‐wide screen of exon‐level expression data (2012) (258)
- KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors. (2009) (237)
- Activity of Sorafenib against Desmoid Tumor/Deep Fibromatosis (2010) (231)
- Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome: A Clinicopathologic and Molecular Study of 115 Cases (2017) (229)
- Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? (2010) (227)
- Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma (2011) (225)
- Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma (2016) (216)
- Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging (2015) (211)
- Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. (2007) (210)
- A Prognostic Nomogram for Prediction of Recurrence in Desmoid Fibromatosis (2013) (205)
- Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial. (2016) (202)
- Diagnosis and management of lipomatous tumors (2008) (199)
- Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. (2004) (192)
- Chemotherapy Is Associated With Improved Survival in Adult Patients With Primary Extremity Synovial Sarcoma (2007) (192)
- Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk. (1999) (190)
- Synovial sarcoma: prognostic significance of tumor size, margin of resection, and mitotic activity for survival. (1996) (189)
- Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. (2007) (188)
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
- Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor) (2010) (179)
- Functional Copy-Number Alterations in Cancer (2008) (170)
- Management of soft-tissue sarcomas: an overview and update. (2000) (170)
- Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1 (2007) (169)
- The Impact of Chemotherapy on the Survival of Patients With High-grade Primary Extremity Liposarcoma (2004) (159)
- A Synovial Sarcoma-Specific Preoperative Nomogram Supports a Survival Benefit to Ifosfamide-Based Chemotherapy and Improves Risk Stratification for Patients (2008) (151)
- Response to Chemotherapy and Predictors of Survival in Adult Rhabdomyosarcoma (2001) (151)
- Laparoscopic Versus Open Gastric Resections for Primary Gastrointestinal Stromal Tumors (GISTs): A Size-Matched Comparison (2011) (147)
- Sorafenib Inhibits the Imatinib-Resistant KITT670I Gatekeeper Mutation in Gastrointestinal Stromal Tumor (2007) (144)
- Validation of the postoperative nomogram for 12‐year sarcoma‐specific mortality (2004) (139)
- A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations (2014) (139)
- Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications (2015) (137)
- Adults with Ewing's sarcoma/primitive neuroectodermal tumor: adverse effect of older age and primary extraosseous disease on outcome. (1999) (135)
- Novel ZC3H7B‐BCOR, MEAF6‐PHF1, and EPC1‐PHF1 fusions in ossifying fibromyxoid tumors—molecular characterization shows genetic overlap with endometrial stromal sarcoma (2014) (134)
- A Postoperative Nomogram for Local Recurrence Risk in Extremity Soft Tissue Sarcomas After Limb-Sparing Surgery Without Adjuvant Radiation (2012) (130)
- Pathologic and Molecular Heterogeneity in Imatinib-Stable or Imatinib-Responsive Gastrointestinal Stromal Tumors (2007) (128)
- Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: Importance of histological subtype with treatment recommendations (2006) (127)
- Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations (2016) (126)
- Recurrent thromboembolic events after ischemic stroke in patients with cancer (2013) (121)
- Impact of intensity-modulated radiation therapy on local control in primary soft-tissue sarcoma of the extremity. (2008) (121)
- Extraskeletal myxoid chondrosarcoma (2008) (119)
- Synovial Sarcoma: The Importance of Size and Location for Survival (2004) (118)
- Predictors of Survival and Recurrence in Primary Leiomyosarcoma (2013) (116)
- Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid‐type fibromatosis by whole‐exome sequencing and genomic analysis (2015) (115)
- Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. (2011) (113)
- Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival. (2012) (113)
- Skeletal Metastases in Myxoid Liposarcoma: An Unusual Pattern of Distant Spread (2007) (112)
- Novel MIR143‐NOTCH fusions in benign and malignant glomus tumors (2013) (111)
- Consistent SMARCB1 homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival material (2014) (108)
- Predicting Outcome by Growth Rate of Locally Recurrent Retroperitoneal Liposarcoma: The One Centimeter Per Month Rule (2009) (108)
- Comparison of local recurrence with conventional and intensity-modulated radiation therapy for primary soft-tissue sarcomas of the extremity. (2014) (108)
- Oncologic Outcomes of Sporadic, Neurofibromatosis-Associated, and Radiation-Induced Malignant Peripheral Nerve Sheath Tumors (2012) (104)
- Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas. (2011) (103)
- The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates Doxorubicin Efficacy in Advanced Sarcomas: Preclinical Investigations and Results of a Phase I Dose-Escalation Clinical Trial (2012) (93)
- Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. (2011) (93)
- MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition (2015) (93)
- Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients (2021) (91)
- Objective Response Rate Among Patients With Locally Advanced or Metastatic Sarcoma Treated With Talimogene Laherparepvec in Combination With Pembrolizumab: A Phase 2 Clinical Trial. (2020) (91)
- The miR-17-92 Cluster and Its Target THBS1 Are Differentially Expressed in Angiosarcomas Dependent on MYC Amplification (2012) (91)
- Pulmonary metastasectomy with therapeutic intent for soft‐tissue sarcoma (2017) (87)
- Mechanisms of Sunitinib Resistance in Gastrointestinal Stromal Tumors Harboring KITAY502-3ins Mutation: An In vitro Mutagenesis Screen for Drug Resistance (2009) (86)
- Drug Synergy Screen and Network Modeling in Dedifferentiated Liposarcoma Identifies CDK4 and IGF1R as Synergistic Drug Targets (2013) (81)
- Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. (1998) (80)
- IGF2 over‐expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting (2010) (78)
- Dermatofibrosarcoma protuberans (DFSP): Predictors of Recurrence and the Use of Systemic Therapy (2011) (77)
- Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells (2008) (77)
- Circulating angiogenic factor levels correlate with extent of disease and risk of recurrence in patients with soft tissue sarcoma. (2004) (76)
- Evaluation of a Clinically Applicable Post-Surgical Classification System for Primary Retroperitoneal Soft-Tissue Sarcoma (2004) (76)
- Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. (2006) (74)
- A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. (2008) (73)
- Outcome of Metastatic GIST in the Era before Tyrosine Kinase Inhibitors (2007) (73)
- Extraskeletal myxoid chondrosarcoma with non-EWSR1-NR4A3 variant fusions correlate with rhabdoid phenotype and high-grade morphology. (2014) (72)
- Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression. (2006) (71)
- Prognostic Factors for Survival in Patients With Locally Recurrent Extremity Soft Tissue Sarcomas (2005) (70)
- Blood Neutrophil-to-Lymphocyte Ratio is Prognostic in Gastrointestinal Stromal Tumor (2013) (70)
- Why Do Patients with Low-Grade Soft Tissue Sarcoma Die? (2008) (64)
- The enigma of myxofibrosarcoma of the extremity (2012) (63)
- Influence of site on the therapeutic ratio of adjuvant radiotherapy in soft-tissue sarcoma of the extremity. (2005) (62)
- Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation (2005) (62)
- Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study. (2015) (62)
- Advances in sarcoma genomics and new therapeutic targets (2011) (62)
- Cryptogenic Subtype Predicts Reduced Survival Among Cancer Patients With Ischemic Stroke (2014) (61)
- Local control comparison of adjuvant brachytherapy to intensity‐modulated radiotherapy in primary high‐grade sarcoma of the extremity (2011) (60)
- Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols. (2013) (60)
- Long-term salvageability for patients with locally recurrent soft-tissue sarcomas. (1992) (59)
- Prognostic stratification of clinical and molecular epithelioid hemangioendothelioma subsets (2019) (59)
- Intensity modulated radiation therapy for primary soft tissue sarcoma of the extremity: preliminary results. (2007) (58)
- Rectal Gastrointestinal Stromal Tumor (GIST) in the Era of Imatinib: Organ Preservation and Improved Oncologic Outcome (2017) (57)
- Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat. (2001) (56)
- Size and Location are the Most Important Risk Factors for Malignant Behavior in Resected Solitary Fibrous Tumors (2017) (56)
- High-risk features in radiation-associated breast angiosarcomas (2013) (55)
- Copy Number Losses Define Subgroups of Dedifferentiated Liposarcoma with Poor Prognosis and Genomic Instability (2012) (55)
- Cytoreductive Surgery for Metastatic Gastrointestinal Stromal Tumors Treated With Tyrosine Kinase Inhibitors: A 2-institutional Analysis (2017) (53)
- SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors (2012) (53)
- Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma. (2016) (51)
- Toward Better Soft Tissue Sarcoma Staging: Building on American Joint Committee on Cancer Staging Systems Versions 6 and 7 (2013) (50)
- ATRX is a regulator of therapy induced senescence in human cells (2017) (49)
- A Differentiation-Based Phylogeny of Cancer Subtypes (2010) (47)
- Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft‐tissue sarcoma of the extremity (2007) (46)
- Surgical management of soft-tissue sarcoma. (1997) (46)
- GLI1-amplifications expand the spectrum of soft tissue neoplasms defined by GLI1 gene fusions (2019) (46)
- Outcome of 1000 Patients With Gastrointestinal Stromal Tumor (GIST) Treated by Surgery in the Pre- and Post-imatinib Eras (2019) (46)
- Influence of compartmental involvement on the patterns of morbidity in soft tissue sarcoma of the thigh (2009) (46)
- Outcome of Metastatic GIST in the Era before Tyrosine Kinase Inhibitors (2006) (45)
- Pediatric and Adolescent Synovial Sarcoma: Multivariate Analysis of Prognostic Factors and Survival Outcomes (2012) (44)
- High‐resolution MAS NMR spectroscopy detection of the spin magnetization exchange by cross‐relaxation and chemical exchange in intact cell lines and human tissue specimens (2006) (42)
- Multiple primary soft tissue sarcomas (2004) (42)
- miR-193b-Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells. (2017) (42)
- ZIC1 overexpression is oncogenic in liposarcoma. (2010) (42)
- Long‐term outcomes in extremity soft tissue sarcoma after a pathologically negative re‐resection and without radiotherapy (2008) (41)
- Enoxaparin vs Aspirin in Patients With Cancer and Ischemic Stroke: The TEACH Pilot Randomized Clinical Trial (2018) (40)
- Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma. (2019) (39)
- Posterior Reversible Encephalopathy Syndrome in Patients With Cancer. (2015) (39)
- Targeted exome sequencing profiles genetic alterations in leiomyosarcoma (2016) (37)
- Association of MRI T2 Signal Intensity With Desmoid Tumor Progression During Active Observation: A Retrospective Cohort Study. (2020) (34)
- Biochemical correlates of thiazolidinedione‐induced adipocyte differentiation by high‐resolution magic angle spinning NMR spectroscopy (2002) (33)
- PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence (2018) (32)
- Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma (2016) (30)
- Water suppression without signal loss in HR-MAS 1H NMR of cells and tissues. (2004) (28)
- A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas. (2015) (28)
- Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma. (2016) (26)
- Effectiveness of Palliative Procedures for Intra-Abdominal Sarcomas (2005) (26)
- Small-molecule targeting of translation initiation for cancer therapy (2013) (26)
- BCOR upregulation in a poorly differentiated synovial sarcoma with SS18L1‐SSX1 fusion—A pathologic and molecular pitfall (2017) (26)
- Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-g ligand troglitazone in patients with liposarcoma (nuclear receptorsysarcomaydrug developmentyoncologyyantineoplastic) (1999) (25)
- Isotropic susceptibility shift under MAS: The origin of the split water resonances in 1H MAS NMR spectra of cell suspensions (2003) (25)
- A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor (2018) (25)
- mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma (2011) (24)
- Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing (2015) (24)
- Translocation t(8;13)(p11;q11‐12) in stem cell leukemia/lymphoma of t‐cell and myeloid lineages (1995) (23)
- Subdural hematoma in patients with cancer. (2012) (22)
- Application of molecular biology to individualize therapy for patients with liposarcoma. (2015) (22)
- Restoration of C/EBPα in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis (2012) (22)
- New diagnostic modalities in soft tissue sarcoma. (1999) (21)
- A Phase I Study of Binimetinib (MEK162) Combined with Pexidartinib (PLX3397) in Patients with Advanced Gastrointestinal Stromal Tumor (2019) (20)
- CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers (2012) (20)
- Prognostic Factors and Survival in Pediatric and Adolescent Liposarcoma (2012) (19)
- Resolution of creatine and phosphocreatine 1H signals in isolated human skeletal muscle using HR‐MAS 1H NMR (2008) (19)
- Diagnostic yield of echocardiography in cancer patients with ischemic stroke (2015) (18)
- miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFβ, and Wnt signaling (2019) (17)
- Reconstruction After Soft Tissue Sarcoma Resection in the Setting of Brachytherapy: A 10-Year Experience (2004) (17)
- Femoral Fracture in Primary Soft-Tissue Sarcoma of the Thigh and Groin Treated with Intensity-Modulated Radiation Therapy: Observed versus Expected Risk (2019) (17)
- Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival (2020) (17)
- Clinical Outcome of Leiomyosarcomas With Somatic Alteration in Homologous Recombination Pathway Genes. (2020) (16)
- Soft tissue sarcoma of the head & neck: Nomogram validation and analysis of staging systems (2015) (16)
- A phase II study of MEK162 (binimetinib [BINI]) in combination with imatinib in patients with untreated advanced gastrointestinal stromal tumor (GIST). (2015) (15)
- Fat‐free MRI based on magnetization exchange (2010) (15)
- Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets (2021) (15)
- Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy (2005) (14)
- Soft Tissue Sarcomas (2012) (13)
- Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma (2022) (13)
- Histologic Subtype Defines the Risk and Kinetics of Recurrence and Death for Primary Extremity/Truncal Liposarcoma (2019) (12)
- Yield of Colonoscopy in Identification of Newly Diagnosed Desmoid-Type Fibromatosis with Underlying Familial Adenomatous Polyposis (2019) (11)
- Chapter 4 – High-Resolution Magic Angle Spinning NMR Spectroscopy (2007) (11)
- Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma (2022) (10)
- A phase 2 study of epacadostat and pembrolizumab in patients with advanced sarcoma. (2019) (10)
- Prognostic Factors After Neoadjuvant Imatinib for Newly Diagnosed Primary Gastrointestinal Stromal Tumor (2020) (9)
- Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center (2022) (9)
- The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways (2020) (9)
- Impact of ifosfamide-based chemotherapy on survival in patients with primary extremity synovial sarcoma. (2004) (8)
- Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified liposarcoma. (2013) (8)
- A phase II study of talimogene laherparepvec (T-VEC) and pembrolizumab in patients with metastatic sarcoma. (2018) (8)
- Patterns of deregulation of insulin growth factor signalling pathway in paediatric and adult gastrointestinal stromal tumours. (2012) (8)
- Ipilimumab for recurrent glioblastoma (GBM). (2014) (7)
- A Phase Ib/II Randomized Study of RO4929097, a Gamma Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma. (2022) (6)
- Empirical insights into the stochasticity of small RNA sequencing (2016) (6)
- Proton radiotherapy for recurrent or metastatic sarcoma with palliative quad shot (2021) (6)
- SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells. (2017) (6)
- Phase II trial of the CDK4 inhibitor PD0332991 in CDK4-amplified liposarcoma. (2012) (6)
- Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor (2022) (6)
- De novo subacute cutaneous lupus erythematosus‐like eruptions in the setting of programmed death‐1 or programmed death ligand‐1 inhibitor therapy: clinicopathological correlation (2020) (6)
- An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study (2013) (6)
- Activity of sorafenib in radiation-associated breast angiosarcomas harboring MYC and FLT4 amplifications. (2012) (5)
- Extraskeletal myxoid chondrosarcoma with non-EWSR1- NR4A3 variant fusions correlate with rhabdoid phenotype (2014) (5)
- CHECKMATE 647: A PHASE 2, OPEN‐LABEL STUDY OF NIVOLUMAB IN RELAPSED/REFRACTORY PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA OR RELAPSED/REFRACTORY PRIMARY TESTICULAR LYMPHOMA (2017) (5)
- Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma (2021) (5)
- Statistical Assessment of Depth Normalization for Small RNA Sequencing (2020) (5)
- A phase I trial of doxorubicin and flavopiridol in soft tissue sarcoma. (2006) (4)
- Rituximab and Bendamustine for CNS Involvement by Chronic Lymphocytic Leukemia (P7.261) (2014) (4)
- Percutaneous Cryoablation Provides Disease Control for Extra-Abdominal Desmoid-Type Fibromatosis Comparable with Surgical Resection (2021) (4)
- ET-53IPILIMUMAB FOR RECURRENT GLIOBLASTOMA (GBM) (2014) (4)
- NEURO/MEDICAL ONCOLOGY (2013) (4)
- Phase 1/2 trial of bevacizumab plus TPI 287, a brain penetrable anti-microtubule agent, in patients with recurrent glioblastoma. (2016) (4)
- A phase 1b study of avelumab plus DCC-3014, a potent and selective inhibitor of colony stimulating factor 1 receptor (CSF1R), in patients with advanced high-grade sarcoma. (2021) (4)
- Soft tissue sarcoma diagnosed subsequent to lymphoma is associated with prior radiotherapy and decreased survival (2011) (4)
- The clinical impact of performing routine next generation sequencing (NGS) in gastrointestinal stromal tumors (GIST). (2017) (4)
- Local Control Comparison of Conventional and Intensity Modulated Radiation Therapy (IMRT) for Primary Soft-Tissue Sarcomas of the Extremity (2013) (3)
- Integrin-alpha10 drives tumorigenesis in sarcoma (2017) (3)
- Final results from the dose-escalation stage of a phase 1/2 trial of TPI 287, a brain penetrable microtubule inhibitor, plus bevacizumab in patients with recurrent glioblastoma. (2017) (3)
- Kinase Mutat ions and Imat inib Response in Pat ients With Metastat ic Gastro intes t inal Stromal Tumor (2003) (3)
- Preclinical study of treatment response in HCT‐116 cells and xenografts with 1H‐decoupled 31P MRS (2011) (3)
- Comprehensive genomic profiling of EWSR1/FUS-CREB translocation-associated tumors uncovers prognostically significant recurrent genetic alterations and methylation-transcriptional correlates (2022) (3)
- Modern Soft Tissue Pathology: SURGICAL MANAGEMENT OF SOFT TISSUE SARCOMA: HISTOLOGIC TYPE AND GRADE GUIDE SURGICAL PLANNING AND INTEGRATION OF MULTIMODALITY THERAPY (2010) (2)
- Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors (2022) (2)
- The Oncolytic Activity of Myxoma Virus against Soft Tissue Sarcoma Is Mediated by the Overexpression of Ribonucleotide Reductase (2021) (2)
- Femoral Fracture in Primary Soft Tissue Sarcoma Treated with Intensity-Modulated Radiation Therapy with and Without Dose Constraints (2020) (2)
- Chapter 5 – Chromatographic and Electrophoretic Separations Combined with Mass Spectrometry for Metabonomics (2007) (2)
- Treatment Recommendations for Retroperitoneal Liposarcoma. (2017) (2)
- FGFR2::TACC2 fusion as a novel KIT‐independent mechanism of targeted therapy failure in a multidrug‐resistant gastrointestinal stromal tumor (2022) (2)
- Expanding the Molecular Diversity of CIC-Rearranged Sarcomas With Novel and Very Rare Partners. (2023) (2)
- Histopathologic Grading Is of Prognostic Significance in Primary Angiosarcoma of Breast (2022) (2)
- Association of Notch signaling pathway expression in liposarcomas with outcome, and targeting with gamma-secretase inhibitors. (2009) (2)
- Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses (2022) (2)
- A putative tumor suppressor role for Wnt-signaling in sarcomagenesis. (2006) (2)
- Myxoid pleomorphic liposarcoma is distinguished from other liposarcomas by widespread loss of heterozygosity and significantly worse overall survival: a genomic and clinicopathologic study (2022) (2)
- Local Control Comparison of IMRT vs. Brachytherapy in Primary High-grade Extremity Sarcoma (2009) (2)
- ACTR-28. FINAL RESULTS FROM THE DOSE-ESCALATION STAGE OF A PHASE 1/2 TRIAL OF TPI 287, A BRAIN PENETRABLE MICROTUBULE INHIBITOR, PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA (2017) (1)
- A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma (2021) (1)
- MicroRNA-143 as a tumor suppressor in liposarcoma (2010) (1)
- EBV-Positive Primary CNS Lymphomas in Older Patients: Incidence, Characteristics, Tumor Pathology, and Outcomes across a Large Multicenter Cohort (2020) (1)
- Patterns of Morbidity by Compartments in Soft Tissue Sarcoma (STS) of the Thigh (2007) (1)
- Enhanced PAtient Clinical Streamlining (EPACS): Quality Initiative to Improve Healthcare for New Surgical Outpatient Visits (2022) (1)
- 1527MO Biomarkers of response and hyperprogression in patients with sarcoma treated with checkpoint blockade (2021) (1)
- A tribute to Murray F. Brennan, MD (2008) (1)
- AT-24PHASE 1/2 TRIAL OF BEVACIZUMAB PLUS TPI 287, A NOVEL BRAIN PENETRABLE ANTI-MICROTUBULE AGENT, FOR THE TREATMENT OF RECURRENT GLIOBLASTOMA (2014) (1)
- Real World (RW) Outcomes and Prognostication of Older Patients with Primary Central Nervous System Lymphoma (PCNSL) in the Contemporary Era (2020) (1)
- tumors harboring KIT AY502-3ins mutation: an in vitro mutagenesis screen for drug-resistance (2010) (1)
- ATIM-05. COMPLEMENTARY CLINICAL AND ANCILLARY DATA FROM 123 PATIENTS WITH RECURRENT HIGH GRADE GLIOMA FROM THREE PHASE 1 TRIALS OF TOCA 511 AND TOCA FC: UPDATE AND JUSTIFICATION FOR A PHASE 2/3 TRIAL (2016) (1)
- SN-38 is a potential targeted chemotherapeutic for dedifferentiated liposarcoma (2010) (1)
- Abstract WP230: The Yield of Echocardiography in Cancer Patients with Suspected Cardioembolic Stroke (2013) (1)
- Survival of Adult Rhabdomyosarcoma Patients Treated on Multimodality Protocols (2012) (1)
- Significance of necrosis and gene expression profiling in high-grade myxoid/round cell liposarcoma (MRLS) of the extremity (2005) (1)
- Low‐grade endometrial stromal sarcoma‐like tumors in male with JAZF1 gene fusions (2021) (1)
- Long Term Outcomes in Extremity Soft Tissue Sarcoma (STS) After a Pathologically Negative Re-Resection and Without Radiotherapy (RT) (2007) (1)
- Identification of selective inhibitors of dedifferentiated liposarcoma cells by high-throughput screening (HTS). (2010) (1)
- Supplementary Material 10 (2014) (1)
- Marantic Endocarditis (ME) Markedly Reduces Survival in Cancer Patients with Ischemic Stroke (P07.002) (2013) (1)
- A Nomogram for Local Recurrence Risk in Extremity Soft Tissue Sarcomas after Limb-sparing Surgery without Adjuvant Radiation (2008) (1)
- Local Recurrence in Myxofibrosarcoma of the Extremity (2010) (1)
- Five decades of sarcoma care at Memorial Sloan Kettering Cancer Center (2022) (1)
- SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors (2012) (1)
- A Transplant Perspective on ‘Non-Resectable’ Soft Tissue Tumors at the Root of the Mesentery – Procedures, Promise and Pitfalls! (2011) (0)
- ACTR-47. TPI 287, A BRAIN PENETRABLE ANTI-MICROTUBULE AGENT, PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: RESULTS FROM A DOSE ESCALATION PHASE 1/2 CLINICAL TRIAL (2016) (0)
- A phase Ib study of BGJ398 in combination with imatinib in patients with advanced gastrointestinal stromal tumor (GIST). (2017) (0)
- The genetic landscape of SMARCB1 alterations in SMARCB1-deficient spectrum of mesenchymal neoplasms (2022) (0)
- The Influence of Older Age on Outcome in Soft Tissue Sarcoma of the Extremity (2005) (0)
- miRNA profiling of liposarcoma identifies distinct subtypes and potential therapeutic targets (2009) (0)
- Older Patients with Primary Central Nervous System Lymphoma: Survival and Prognostication Across 20 US Cancer Centers. (2023) (0)
- Combination of primary and recurrent tumor characteristics predict survival in locally recurrent extremity soft tissue sarcoma (2004) (0)
- Poor prognostic features in angiosarcoma: A single institution retrospective study of 324 patients. (2013) (0)
- ASO Visual Abstract: Feasibility of Preoperative Dose-Painting Intensity-Modulated Radiation Therapy (IMRT) for Borderline Resectable Primary Retroperitoneal Sarcoma (2022) (0)
- Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic therapeutic viruses (2022) (0)
- Flavopiridol inhibits soft tissue sarcoma growth with preferential sensitivity in a CDK4 gene amplified subtype (2004) (0)
- ATCT-15CB-018: A PHASE 2 TRIAL OF BEVACIZUMAB PLUS TPI 287, A NOVEL BRAIN PENETRABLE ANTI-MICROTUBULE AGENT, IN PATIENTS WITH RECURRENT GLIOBLASTOMA FOLLOWING PROGRESSION ON ANTI-ANGIOGENIC THERAPY (2015) (0)
- Abstract 5061: Genomic and functional analysis of Myxofibrosarcoma identifies novel prognostic markers and promising therapeutic targets (2012) (0)
- EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort. (2023) (0)
- Abstract CT314: Interim results from a phase I/II trial of TPI 287, a novel brain penetrable antimicrotubule agent, in combination with bevacizumab for the treatment of recurrent glioblastoma (2015) (0)
- The Feasibility of Hypofractionated Preoperative Intensity Modulated Radiation Therapy to a Partial Tumor Volume in Retroperitoneal Sarcoma: Dosimetric Analysis (2008) (0)
- Abstract B11: An empirical evaluation of array normalization for Agilent microRNA expression arrays (2010) (0)
- Association of perioperative radiation therapy with outcome in 204 patients with primary retroperitoneal sarcoma: A two-institution study. (2013) (0)
- Ribonucleotide reductase M2 subunit as novel target for liposarcoma (2006) (0)
- Amplification of full-length HMGA2 is oncogenic in liposarcoma (2012) (0)
- Abstract PR16: Multiplatform analysis of paired primary and recurrent well- and dedifferentiated liposarcoma samples defines copy number alterations as dominant drivers of initiation and progression (2018) (0)
- CLIN-NEURO/MEDICAL ONCOLOGY (2012) (0)
- Radiation Therapy in Primary Soft Tissue Sarcoma of the Superficial Trunk (2021) (0)
- Short KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors (2000) (0)
- CAN-10-0745 Cancer esearch apeutics , Targets , and Chemical Biology R 1 Overexpression Is Oncogenic in Liposarcoma (2010) (0)
- Abstract 3100: The RNA-binding protein insulin-like growth factor 2 mRNA-binding protein 3 is oncogenic in liposarcoma (2010) (0)
- NMR detectable cholesterol is an early marker of tumor response to cytotoxic chemotherapy in colon cancer xenografts (2005) (0)
- 209: Preliminary Results of IMRT in Primary Soft Tissue Sarcoma of the Extremity (2006) (0)
- Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert tumor microenvironment and confers resistance to immunotherapy (2022) (0)
- Imaging , Diagnosis , Prognosis Copy Number Losses De fi ne Subgroups of Dedifferentiated Liposarcoma with Poor Prognosis and Genomic Instability (2012) (0)
- How well do we communicate risk? An evaluation of AJCC version 6 and 7 staging systems for soft tissue sarcomas. (2012) (0)
- Abstracts reprinted from Journal of Clinical Oncology (2007) (0)
- TRAF7-mutated Fibromyxoid Spindle Cell Tumors Are Associated With an Aggressive Clinical Course and Harbor an Undifferentiated Sarcoma Methylation Signature (2022) (0)
- Study of genetic alterations in soft tissue sarcomas by SNP arrays, expression profiling and high-throughput sequencing (2007) (0)
- Genomic Clustering Identifies an Aggressive Subset of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Sensitive to Mammalian Target of Rapamycin (mTOR) and Insulin-Like Growth Factor 1 (IGF1) Receptor Inhibitors (2018) (0)
- Impact of Tumor Histology on Local Control in Patients with Primary Soft Tissue Sarcoma of the Extremity (2018) (0)
- Molecular profiling of liposarcoma subtypes (2005) (0)
- 698 Evaluation of a clinically applicable post-surgical classification system for primary retroperitoneal soft tissue sarcoma (2003) (0)
- Abstract B008: Investigating the evolution of undifferentiated soft tissue sarcomas in a genetically engineered mouse model (2022) (0)
- ATRX is a regulator of therapy induced senescence in human cells (2017) (0)
- ATNT-08CB-017: A PHASE 1/2 TRIAL OF BEVACIZUMAB PLUS TPI 287, A NOVEL BRAIN PENETRABLE ANTI-MICROTUBULE AGENT, IN PATIENTS WITH RECURRENT GLIOBLASTOMA NAÏVE TO ANTI-ANGIOGENIC THERAPY (2015) (0)
- miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFβ, and Wnt signaling (2019) (0)
- ASO Visual Abstract: Enhanced PAtient Clinical Streamlining (EPACS)—Quality Initiative to Improve Healthcare for New Surgical Outpatient Visits (2022) (0)
- Feasibility of Preoperative Dose-Painting Intensity Modulated Radiation Therapy (IMRT) for Borderline-Resectable Primary Retroperitoneal Sarcoma (2022) (0)
- Abstract IA18: Integrin-α10 drives metastasis and sarcomagenesis in mxyofibrosarcoma and undifferentiated pleomorphic sarcoma (2018) (0)
- Kinase M utations a nd I matinib R esponse i n P atients W ith Metastatic G astrointestinal S tromal T umor (2003) (0)
- Supplementary Material 8 (2013) (0)
- OLDER PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL): REAL WORLD (RW) OUTCOMES OF POST‐INDUCTION THERAPY IN THE MODERN ERA (2021) (0)
- Abstract PR012: Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets (2022) (0)
- Histology-Specific Prognostication for Radiation-Associated Soft Tissue Sarcoma. (2022) (0)
- Functional Copy-Number Alterations in Cancer article openly available. Please share how this access benefits you. Your story matters (2008) (0)
- IMCT-05COMBINABILITY OF TOCA FC AND TOCA 511 WITH CHEMOTHERAPY AND TARGETED AGENTS (2015) (0)
- Prognostic V alue o f KIT Mutation T ype, M itotic A ctivity, and H istologic S ubtype i n G astrointestinal S tromal Tumors (2002) (0)
- Long-Term O utcomes A fter F unction-Sparing S urgery Without R adiotherapy f or S oft T issue S arcoma of t he E xtremities a nd T runk (1999) (0)
- Abstract 6164: Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert tumor microenvironment (2022) (0)
- Angiosarcoma. (2020) (0)
- Feasibility of Preoperative Dose-Painting Intensity Modulated Radiation Therapy (IMRT) for Borderline Resectable/Unresectable Primary Retroperitoneal Sarcoma (2020) (0)
- A prognostic nomogram for prediction of recurrence following surgical resection of desmoid tumors. (2012) (0)
- CTNI-03. EXTENDED BENEFITS IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA THAT CONTINUOUSLY RECEIVE TOCA FC AFTER TOCA 511 TREATMEN (2021) (0)
- Primary high-grade myxofibrosarcoma/pleomorphic malignant fibrous histiocytoma: Percent myxoid component to improve outcome prediction. (2015) (0)
- Ipilimumab for recurrent glioblastoma (GBM) (P3.131) (2015) (0)
- 3:54 PM Abstract No. 258 Percutaneous cryoablation of extra-abdominal desmoid tumors as first-line and salvage therapy (2018) (0)
- β-catenin loss-of-function and its putative role as a tumor suppressor in sarcomagenesis (2006) (0)
- Senescence after growth arrest: A mechanism by which CDK4/6 inhibitors can mediate their activity suppressing tumor progression (2018) (0)
- Checkpoint kinase 1 (CHEK1) gene expression is associated with metastasis and essential for the survival of dedifferentiated liposarcoma (LS) cells (2010) (0)
- Abstract A028: Growth factor signaling and kinase inhibitors regulate oncogenesis in desmoid fibromatosis by modulating activity of the beta-catenin transcription target ABL1 (2022) (0)
- Undifferentiated and Dedifferentiated Metastatic Melanomas Masquerading as Soft Tissue Sarcomas: Mutational Signature Analysis and Immunotherapy Response. (2023) (0)
- Abstract 6168: Beta-catenin and PDGFRB modulate HIF1a in desmoid cells to promote sorafenib-sensitive paracrine signaling pathways (2022) (0)
- Soft Tissue Sarcoma (2020) (0)
- A multigene predictor improves risk stratification for patients with liposarcoma (2009) (0)
- Abstract 4972: High-throughput functional profiling of dedifferentiated liposarcoma cell lines (2011) (0)
- Independent Predictors of Recurrent Thromboembolic Events in Patients with Cancer and Ischemic Stroke (S35.006) (2013) (0)
- Abstract TP72: Pilot Trial of Enoxaparin versus Aspirin in Cancer Patients with Stroke: the TEACH Study (2017) (0)
- Abstract 516: Long noncoding RNA NEAT1 promotes lung metastasis of soft tissue sarcoma (2018) (0)
- Targeting the Proangiogenic Network in Angiosarcomas: Biomodulatory Therapy (2013) (0)
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What Schools Are Affiliated With Samuel Singer?
Samuel Singer is affiliated with the following schools:
