Samuel Weiss
#86,983
Most Influential Person Now
Canadian biochemist
Samuel Weiss 's AcademicInfluence.com Rankings
Samuel Weiss biology Degrees
Biology
#9077
World Rank
#12236
Historical Rank
Biochemistry
#1635
World Rank
#1770
Historical Rank
Download Badge
Biology
Why Is Samuel Weiss Influential?
(Suggest an Edit or Addition)According to Wikipedia, Samuel Weiss is a Canadian neurobiologist. Biography Weiss was an undergraduate at McGill University, where he received a B.Sc. in Biochemistry in 1978. He then went on to take his Ph.D. in Neurobiology at the University of Calgary. From 1983 to 1988 he held two postdoctoral fellowships funded by the AHFMR and the Medical Research Council of Canada , the first at the Centre de Pharmacologie-Endocologie, Montpellier, France, and the second at the University of Vermont College of Medicine. He was appointed Assistant Professor and MRC Scholar at The University of Calgary in 1988.
Samuel Weiss 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. (1992) (5445)
- A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes (1992) (1557)
- Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells (1994) (1463)
- Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. (1996) (1448)
- Multipotent CNS Stem Cells Are Present in the Adult Mammalian Spinal Cord and Ventricular Neuroaxis (1996) (1254)
- In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain (1996) (746)
- Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin (2003) (689)
- bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells (1993) (686)
- Erythropoietin Regulates the In Vitro and In Vivo Production of Neuronal Progenitors by Mammalian Forebrain Neural Stem Cells (2001) (673)
- Brain tumour cells interconnect to a functional and resistant network (2015) (655)
- Is there a neural stem cell in the mammalian forebrain? (1996) (557)
- Aging Results in Reduced Epidermal Growth Factor Receptor Signaling, Diminished Olfactory Neurogenesis, and Deficits in Fine Olfactory Discrimination (2004) (534)
- BDNF enhances the differentiation but not the survival of CNS stem cell- derived neuronal precursors (1995) (360)
- Male pheromone–stimulated neurogenesis in the adult female brain: possible role in mating behavior. (2007) (311)
- The Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor/gp130 Receptor Complex Operates in the Maintenance of Mammalian Forebrain Neural Stem Cells (2001) (301)
- Why stem cells? (2000) (296)
- Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers (2012) (273)
- The bHLH Gene Hes1 as a Repressor of the Neuronal Commitment of CNS Stem Cells (2000) (264)
- Insulin-Like Growth Factor-I Is Necessary for Neural Stem Cell Proliferation and Demonstrates Distinct Actions of Epidermal Growth Factor and Fibroblast Growth Factor-2 (2001) (257)
- Growth Factor-Stimulated Generation of New Cortical Tissue and Functional Recovery after Stroke Damage to the Motor Cortex of Rats (2007) (249)
- Insulin-Like Growth Factor-I Is a Differentiation Factor for Postmitotic CNS Stem Cell-Derived Neuronal Precursors: Distinct Actions from Those of Brain-Derived Neurotrophic Factor (1998) (247)
- White Matter Plasticity and Enhanced Remyelination in the Maternal CNS (2007) (224)
- Paternal recognition of adult offspring mediated by newly generated CNS neurons (2010) (196)
- The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice (1994) (195)
- Neurotalk: improving the communication of neuroscience research (2010) (179)
- Glycoprotein 130 Signaling Regulates Notch1Expression and Activation in the Self-Renewal of Mammalian Forebrain Neural Stem Cells (2003) (179)
- Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens (2009) (174)
- An in vivo patient-derived model of endogenous IDH1-mutant glioma. (2012) (159)
- Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both? (2009) (156)
- Lactate dehydrogenase A silencing in IDH mutant gliomas. (2014) (151)
- Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells (2008) (143)
- Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells (2013) (138)
- Generation of Tyrosine Hydroxylase-Producing Neurons from Precursors of the Embryonic and Adult Forebrain (1999) (130)
- Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate (2009) (118)
- Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma (2016) (114)
- Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. (2013) (104)
- Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons (1993) (103)
- Generation of Functional Radial Glial Cells by Embryonic and Adult Forebrain Neural Stem Cells (2003) (102)
- Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells. (2019) (102)
- IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. (2015) (99)
- Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1 (2017) (93)
- On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells. (2013) (91)
- CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain (2005) (91)
- Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity (2021) (85)
- Oligodendroglioma cell lines containing t(1;19)(q10;p10). (2010) (79)
- Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor (2008) (77)
- CNS stem cells: where's the biology (a.k.a. beef)? (1998) (75)
- Retinoic acid enhances neuronal proliferation and astroglial differentiation in cultures of CNS stem cell-derived precursors. (1998) (73)
- Sensitivity to temozolomide in brain tumor initiating cells. (2010) (69)
- Isolation of a Novel Platelet-Derived Growth Factor-Responsive Precursor from the Embryonic Ventral Forebrain (2004) (66)
- Control of glioblastoma tumorigenesis by feed-forward cytokine signaling (2016) (66)
- Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma (2020) (66)
- Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth (2013) (55)
- Novel MSH6 Mutations in Treatment-Naïve Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation (2014) (52)
- Pituitary adenylate cyclase‐activating polypeptide regulates forebrain neural stem cells and neurogenesis in vitro and in vivo (2006) (51)
- A role for the POU‐III transcription factor Brn‐4 in the regulation of striatal neuron precursor differentiation (1999) (50)
- Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes (2015) (49)
- Prolactin in multiple sclerosis (2013) (46)
- Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. (2013) (46)
- PRMT5 inhibition disrupts splicing and stemness in glioblastoma (2021) (45)
- Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin. (2013) (44)
- Platelet‐derived growth factor‐responsive neural precursors give rise to myelinating oligodendrocytes after transplantation into the spinal cords of contused rats and dysmyelinated mice (2011) (42)
- EGF‐responsive neural stem cells are a transient population in the developing mouse spinal cord (2001) (42)
- Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both? (2009) (41)
- The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model (2017) (41)
- PDGFRα Expression Distinguishes GFAP-Expressing Neural Stem Cells from PDGF-Responsive Neural Precursors in the Adult Periventricular Area (2011) (41)
- Dual mTORC1/2 Blockade Inhibits Glioblastoma Brain Tumor Initiating Cells In Vitro and In Vivo and Synergizes with Temozolomide to Increase Orthotopic Xenograft Survival (2014) (41)
- Differential properties of dentate gyrus and CA1 neural precursors. (2005) (38)
- Spontaneous loss of heterozygosity leading to homozygous R132H in a patient-derived IDH1 mutant cell line. (2013) (35)
- Radial glial cells as neuronal precursors: The next generation? (2002) (34)
- Activin co-operates with fibroblast growth factor 2 to regulate tyrosine hydroxylase expression in the basal forebrain ventricular zone progenitors (1998) (34)
- The Ciliary Neurotrophic Factor / Leukemia Inhibitory Factor / gp 130 Receptor Complex Operates in the Maintenance of Mammalian Forebrain Neural Stem Cells (2001) (32)
- Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments (2019) (29)
- Distinctions between fetal and adult human platelet‐derived growth factor–responsive neural precursors (2008) (28)
- Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival (2021) (28)
- STAT5A/B activity is required in the developing forebrain and spinal cord (2007) (25)
- DNA hypermethylation and 1p Loss silence NHE‐1 in oligodendroglioma (2012) (23)
- Prolactin in combination with interferon-β reduces disease severity in an animal model of multiple sclerosis (2015) (23)
- Evidence for a progenitor cell population in the human pituitary. (2009) (22)
- Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer. (2019) (21)
- A phase I study of vistusertib (dual mTORC1/2 inhibitor) in patients with previously treated glioblastoma multiforme: a CCTG study (2019) (20)
- N-methyl-d-aspartate evokes the release of somatostatin from striatal interneurons in primary culture (1991) (19)
- Pathways for neural stem cell biology and repair (1999) (18)
- Transplantation of Epidermal Growth Factor-Responsive Neural Stem Cell Progeny into the Murine Central Nervous System (1994) (16)
- Cancer therapeutic potential of combinatorial immuno- and vasomodulatory interventions (2015) (16)
- On-target JAK 2 / STAT 3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells (2013) (14)
- A Neuroethics Backbone for the Evolving Canadian Brain Research Strategy (2019) (14)
- EGFR blockade in GBM brain tumor stem cells synergizes with JAK2/STAT3 pathway inhibition to abrogate compensatory mechanisms in vitro and in vivo (2020) (14)
- Bi-Parental Care Contributes to Sexually Dimorphic Neural Cell Genesis in the Adult Mammalian Brain (2013) (12)
- SLUG Directs the Precursor State of Human Brain Tumor Stem Cells (2019) (12)
- Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway (2020) (11)
- Pigment epithelium-derived growth factor: modulating adult neural stem cell self-renewal (2009) (9)
- Central nervous system growth and differentiation factors: clinical horizons--truth or dare? (1993) (8)
- CHAPTER 19 – EGF-Responsive stem cells in the mammalian central nervous system (1993) (8)
- Isolation and Culture of Glioblastoma Brain Tumor Stem Cells. (2018) (8)
- Kainate evokes the release of endogenous glycine from striatal neurons in primary culture (1989) (8)
- Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion (2018) (7)
- Neural stem cells of the mammalian forebrain. (2001) (7)
- In Vitro Modeling of GBM Initiation using PDGF-AA and P53-Null Neural Progenitors. (2020) (7)
- Immunobiology of oligodendrocytes in multiple sclerosis. (2006) (6)
- Adult periventricular neural stem cells: Outstanding progress and outstanding issues (2012) (6)
- Single-cell chromatin accessibility in glioblastoma delineates cancer stem cell heterogeneity predictive of survival (2018) (5)
- EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2013) (2)
- BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM. (2014) (2)
- CSIG-06EGFRvIII REQUIRES OSMR AS A CO-RECEPTOR TO DRIVE GLIOBLASTOMA PATHOGENESIS (2015) (1)
- STEM-28. DOT1L EPIGENETICALLY REGULATES GBM BRAIN TUMOR STEM CELLS (2017) (1)
- LAB-CELL BIOLOGY AND SIGNALING (2012) (1)
- Intrinsic and extrinsic neural stem cell treatment of central nervous system injury and disease (2008) (1)
- Abstract 2524: STAT3 is a key regulator of an “EMT-like” process mediated by Slug in GBM (2016) (1)
- Regulation of glioblastoma stem-like cell self-renewal by FOXG1 and TLE (2012) (0)
- EPCO-28. DOT1L AND PRC2 REGULATE A SHARED EPIGENETIC MECHANISM IN GLIOBLASTOMA AND MIXED LINEAGE LEUKEMIA (2022) (0)
- Do Forebrain Neural Stem Cells Have a Role in Mammalian Olfactory Behavior (2004) (0)
- PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2010) (0)
- Abstract 1118: DOT1L epigenetically regulates cancer stem cell properties and tumor progression in glioblastoma brain tumor stem cells (2018) (0)
- Neuronal Cell Specification from CNS Stem Cells (1995) (0)
- CS-04. STAT3 INVOLVEMENT IN AN EMT-LIKE PROCESS IN GLIOBLASTOMA BRAIN TUMOR INITIATING CELLS (2014) (0)
- Cancer Therapy : Preclinical Dual mTORC 1 / 2 Blockade Inhibits Glioblastoma Brain Tumor Initiating Cells In Vitro and In Vivo and Synergizes with Temozolomide to Increase Orthotopic Xenograft Survival (2014) (0)
- STEM-18. EPIGENETIC AND MOLECULAR COORDINATION BETWEEN HDAC2 AND SMAD3-SKI IS REQUIRED FOR GROWTH AND STEM CELL CHARACTERISTICS OF BRAIN TUMOUR STEM CELLS (2022) (0)
- STEM-21. INVESTIGATING DOT1L AS AN EPIGENETIC VULNERABILITY IN BRAIN TUMOR STEM CELLS (2019) (0)
- STEM-03. MOLECULAR PROFILING OF PRIMARY VERSUS RECURRENT GLIOBLASTOMA BRAIN TUMOR STEM CELLS UNCOVERS SIGNALING MECHANISMS THAT PROMOTE THE AGGRESSIVENESS OF RECURRENT GLIOBLASTOMA (2022) (0)
- Adult neural stem cells: From basic science to therapeutic applications (2010) (0)
- Culturing fetal precursor cells using free floating serum-free conditions. (2013) (0)
- Defining a role for PARP inhibition in the treatment of GBM ” (2015) (0)
- ATPS-52A PRE-CLINICAL COMBINATORIAL STRATEGY TO TARGET THE JAK/STAT AND EGFR PATHWAYS IN GBM (2015) (0)
- CBIO-17. STAT3 IS A CENTRAL REGULATOR OF PROLIFERATION, INVASION, MIGRATION AND METABOLISM IN GBM TUMOR INITIATING CELLS (2016) (0)
- A guide to the pleasures and pitfalls of neuronal cell culture: Protocols for neural cell culture edited by Sergey Fedoroff and Arleen Richardson, Humana Press, 1992. US$49.50 (xiii + 178 pages) ISBN 0 89603 228 0 (1993) (0)
- GLIOMA SPECIFIC PEPTIDES: A PLATFORM FOR MOLECULAR IMAGING AND THERAPEUTIC TARGETING (2014) (0)
- Author response: Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival (2021) (0)
- Summary CNTF / LIF / gp 130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain (0)
- Modification and in situ stem cell manipulation central nervous system. (1994) (0)
- Prolactin in combination with interferon-β reduces disease severity in an animal model of multiple sclerosis (2015) (0)
- LAB-STEM CELLS (2012) (0)
- Increased number of neural stem cells induced by prolactin and therapeutic use thereof (2002) (0)
- A method for propagating neural precursor cells (1996) (0)
- Abstract 967: Single-cell transcriptomics uncovers clonal heterogeneity linked to drug response and cellular phenotype in adult brain tumor stem cells (2019) (0)
- Abstract 4283: Myxoma virotherapy targeting temozolomide-resistant brain tumor initiating cellsin vitroandin vivo (2010) (0)
- CBIO-21. STAT3 REGULATES AN SL/PL TRANSITION IN BTICs THROUGH AN EMT-LIKE PROCESS MEDIATED BY SLUG (2016) (0)
- ATPS-28COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS (2015) (0)
- Production de cellules gliales radiales (2001) (0)
- Abstract 3058: Data and resource sharing: Advancing our understanding of glioblastoma (2018) (0)
- CS-04STAT3 INVOLVEMENT IN AN EMT-LIKE PROCESS IN GLIOBLASTOMA BRAIN TUMOR INITIATING CELLS (2014) (0)
- STEM-41. A SUBSET OF GBM BRAIN TUMOR STEM CELL LINES ARE UNIQUELY DEPENDENT ON GLUTAMINE METABOLISM FOR AMINO ACID SYNTHESIS (2017) (0)
- CBIO-42DOWN REGULATION OF PYRUVATE DEHYDROGENASE ACTIVITY IS ESSENTIAL FOR CELL PROLIFERATION IN IDH1 MUTANT GLIOMA CELLS. (2015) (0)
- Abstract 2521: STAT3 is a central regulator of proliferation, invasion and metabolism in GBM tumor initiating cells (2016) (0)
- ET-35PACRITINIB: A NOVEL JAK/STAT INHIBITOR WITH TRANSLATIONAL RELEVANCE FOR GBM. (2014) (0)
- GENO-10LOSS OF IDH MUTATION IN PATIENT-DERIVED BRAIN TUMOR INITIATING CELLS (2015) (0)
- On growth factors responsive neural precursor cells that can be propagated in vitro. (1992) (0)
- Abstract 3084: BI-907828: A novel, potent MDM2 inhibitor, inhibits GBM brain tumor stem cellsin vitroand prolonged survival in orthotopic xenograft mouse models (2019) (0)
- GENE-31. IDENTIFICATION OF CORE AND CONTEXT-SPECIFIC FITNESS GENES IN GLIOBLASTOMA STEM CELLS VIA GENOME-WIDE CRISPR-Cas9 SCREENS (2019) (0)
- GENT-40. DOT1L EPIGENETICALLY REGULATES AN EMT-LIKE PROCESS IN GBM BTICs (2016) (0)
- CSIG-17. COMPENSATORY ACTIVATION OF STAT3 TRIGGERED BY EGFR INHIBITION: A MECHANISM OF RESISTANCE IN GBM BRAIN TUMOR INITIATING CELLS (2016) (0)
- An in vitro mouse model of GBM with abrupt and predictable onset (2014) (0)
- COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS (2014) (0)
- Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM (2019) (0)
- 2011 Jeremy Jass Prize for Research Excellence in Pathology (2012) (0)
- LAB-TUMOR MODELS (IN VIVO/IN VITRO) (2012) (0)
- Adult Stem Cells to Treat Stroke (2003) (0)
- ABSTRACT Cytokine regulation of neural stem cell fate in the developing mouse CNS (2000) (0)
- Abstract 5724: Revelation of shared transcriptional gradients in glioblastoma tumors and cultured glioma stem cells (2020) (0)
- Abstract 279: Combinatorial strategies for glioblastoma using brain tumor-initiating cells: targeting the JAK/STAT and EGFR pathways (2016) (0)
- Nervous system within the manipulation and modification of stem cells (1996) (0)
- The functional genomic circuitry of human glioblastoma stem cells (2018) (0)
This paper list is powered by the following services:
Other Resources About Samuel Weiss
What Schools Are Affiliated With Samuel Weiss ?
Samuel Weiss is affiliated with the following schools:
