Sander Kersten
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Sander Kersten's Degrees
- PhD Biochemistry University of Amsterdam
- Masters Biomedical Sciences University of Amsterdam
- Bachelors Biology University of Amsterdam
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(Suggest an Edit or Addition)Sander Kersten's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Roles of PPARs in health and disease (2000) (1949)
- Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting (1999) (1433)
- Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. (2011) (1131)
- Peroxisome Proliferator-Activated Receptor Alpha Target Genes (2010) (973)
- Peroxisome proliferator-activated receptor α target genes (2004) (808)
- Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. (1999) (801)
- Mechanisms of nutritional and hormonal regulation of lipogenesis (2001) (628)
- Nutrigenomics: goals and strategies (2003) (628)
- Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene* (2000) (534)
- The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. (2010) (488)
- Integrated physiology and systems biology of PPARα (2014) (423)
- Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus (2015) (415)
- The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity* (2006) (414)
- Physiological regulation of lipoprotein lipase. (2014) (396)
- Kupffer cells promote hepatic steatosis via interleukin‐1β–dependent suppression of peroxisome proliferator‐activated receptor α activity (2010) (391)
- Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. (2006) (320)
- The Direct Peroxisome Proliferator-activated Receptor Target Fasting-induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate Treatment* (2004) (282)
- Podocyte secreted Angiopoietin-like 4 mediates proteinuria in glucocorticoid sensitive nephrotic syndrome (2010) (281)
- PPARs, Obesity, and Inflammation (2006) (274)
- Mechanisms of inflammatory responses in obese adipose tissue. (2012) (269)
- Mechanisms of gene regulation by fatty acids. (2012) (264)
- Peroxisome proliferator activated receptor agonists. (1997) (256)
- Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human (2009) (248)
- Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors. (2011) (239)
- Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. (2010) (235)
- The G0/G1 switch gene 2 is a novel PPAR target gene. (2005) (220)
- Angiopoietin-like 4: a decade of research. (2012) (217)
- The role and regulation of the peroxisome proliferator activated receptor alpha in human liver. (2017) (211)
- Comprehensive Analysis of PPARα-Dependent Regulation of Hepatic Lipid Metabolism by Expression Profiling (2007) (211)
- In vivo activation of PPAR target genes by RXR homodimers (2004) (206)
- ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters. (2011) (201)
- PPARα governs glycerol metabolism (2004) (201)
- Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity* (2012) (193)
- Natural killer T cells in adipose tissue prevent insulin resistance. (2012) (191)
- Peroxisome Proliferator-activated Receptor γ Activation Promotes Infiltration of Alternatively Activated Macrophages into Adipose Tissue* (2008) (188)
- Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation. (2007) (185)
- Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids (2009) (185)
- IL-37 protects against obesity-induced inflammation and insulin resistance (2014) (184)
- Short-Chain Fatty Acids Stimulate Angiopoietin-Like 4 Synthesis in Human Colon Adenocarcinoma Cells by Activating Peroxisome Proliferator-Activated Receptor γ (2013) (183)
- Angptl4 Upregulates Cholesterol Synthesis in Liver via Inhibition of LPL- and HL-Dependent Hepatic Cholesterol Uptake (2007) (182)
- Adipose Tissue Dysfunction Signals Progression of Hepatic Steatosis Towards Nonalcoholic Steatohepatitis in C57Bl/6 Mice (2010) (177)
- The peroxisome proliferator‐activated receptor α regulates amino acid metabolism (2001) (175)
- PPARα and dyslipidemia (2007) (158)
- Regulation of triglyceride metabolism by Angiopoietin-like proteins. (2012) (158)
- Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD (2007) (156)
- Regulation of lipoprotein lipase by Angptl4 (2014) (153)
- The role of the gut microbiota in metabolic health (2015) (153)
- Moderate alcohol consumption increases insulin sensitivity and ADIPOQ expression in postmenopausal women: a randomised, crossover trial (2008) (151)
- The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (151)
- Peroxisome proliferator activated receptors and obesity. (2002) (147)
- IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation (2015) (143)
- Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels (2012) (139)
- Regulation of lipid metabolism by angiopoietin-like proteins (2016) (139)
- Brown adipose tissue takes up plasma triglycerides mostly after lipolysis (2015) (138)
- Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome (2013) (137)
- Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival (2014) (135)
- The glucocorticoid receptor controls hepatic dyslipidemia through Hes1. (2008) (132)
- Angiopoietin-like 4 Interacts with Matrix Proteins to Modulate Wound Healing* (2010) (131)
- Genome-wide analysis of PPARα activation in murine small intestine (2007) (131)
- Identification of human exercise-induced myokines using secretome analysis. (2014) (130)
- Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle (2018) (130)
- Induction of Cardiac Angptl4 by Dietary Fatty Acids Is Mediated by Peroxisome Proliferator-Activated Receptor &bgr;/&dgr; and Protects Against Fatty Acid–Induced Oxidative Stress (2010) (129)
- Effect of Synthetic Dietary Triglycerides: A Novel Research Paradigm for Nutrigenomics (2008) (128)
- PPARalpha governs glycerol metabolism. (2004) (128)
- Peroxisome Proliferator-Activated Receptor β/δ (PPARβ/δ) but Not PPARα Serves as a Plasma Free Fatty Acid Sensor in Liver (2009) (127)
- Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. (2012) (125)
- Angiopoietin-like 3 in lipoprotein metabolism (2017) (122)
- Peroxisome proliferator-activated receptor alpha target genes. (2004) (121)
- Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis (2010) (117)
- Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration. (2010) (116)
- Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society (2021) (115)
- Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise (2014) (113)
- Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity. (2013) (110)
- Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism (2007) (109)
- Pronounced Effects of Acute Endurance Exercise on Gene Expression in Resting and Exercising Human Skeletal Muscle (2012) (101)
- The search for exercise factors in humans (2015) (100)
- Regulation of lipid metabolism via angiopoietin-like proteins. (2005) (99)
- ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure (2015) (99)
- Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1. (2010) (96)
- Retinoid X receptor alpha forms tetramers in solution. (1995) (93)
- Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver. (2010) (93)
- G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase (2012) (88)
- Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice. (2014) (86)
- Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Development (2013) (86)
- Mechanisms of Action of trans Fatty Acids (2019) (85)
- Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes (2016) (85)
- System-wide Benefits of Intermeal Fasting by Autophagy. (2017) (83)
- The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. (2014) (81)
- Molecular mechanisms underlying the potential antiobesity-related diseases effect of cocoa polyphenols. (2014) (76)
- Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids[S] (2017) (76)
- Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue (2012) (75)
- Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. (2006) (75)
- Angiopoietin-like-4 is a potential angiogenic mediator in arthritis. (2005) (74)
- Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity. (2014) (74)
- Metabolic switching of human myotubes is improved by n-3 fatty acids (2010) (74)
- Peroxisome Proliferator-activated Receptor γ Regulates Expression of the Anti-lipolytic G-protein-coupled Receptor 81 (GPR81/Gpr81)* (2009) (72)
- Steroid and nuclear receptors Villefranche‐sur‐Mer, France, May 25–27, 1999 (1999) (70)
- Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid. (2016) (69)
- Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion. (2014) (69)
- The ATP-P2X7 Signaling Axis Is Dispensable for Obesity-Associated Inflammasome Activation in Adipose Tissue (2012) (69)
- Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors (2007) (68)
- The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver. (2007) (67)
- Regulation of lipid droplet-associated proteins by peroxisome proliferator-activated receptors. (2017) (64)
- Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota (2018) (63)
- Hypoxia-inducible Lipid Droplet-associated (HILPDA) Is a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Involved in Hepatic Triglyceride Secretion* (2014) (61)
- Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes (2020) (61)
- Individual subunits of heterodimers comprised of retinoic acid and retinoid X receptors interact with their ligands independently. (1996) (60)
- The impact of PPARα activation on whole genome gene expression in human precision cut liver slices (2015) (60)
- PPARalpha and dyslipidemia. (2007) (59)
- Review Peroxisome proliferator-activated receptor a target genes (2004) (58)
- A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening. (2018) (57)
- Inflammation increases plasma angiopoietin-like protein 4 in patients with the metabolic syndrome and type 2 diabetes (2014) (56)
- Sulfonylureas and Glinides Exhibit Peroxisome Proliferator-Activated Receptor γ Activity: A Combined Virtual Screening and Biological Assay Approach (2007) (55)
- PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism. (2014) (54)
- Exploration of PPAR functions by microarray technology--a paradigm for nutrigenomics. (2007) (54)
- CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis (2016) (53)
- New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk (2019) (52)
- Energy-sensing Factors Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator 1-α (PGC-1α) and AMP-activated Protein Kinase Control Expression of Inflammatory Mediators in Liver (2011) (51)
- Potential mediators linking gut bacteria to metabolic health: a critical view (2016) (51)
- Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase (2018) (50)
- Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes. (2013) (47)
- Angiopoietin-like 4 promotes the intracellular cleavage of lipoprotein lipase by PCSK3/furin in adipocytes (2018) (47)
- Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) (2010) (45)
- Role of ligand in retinoid signaling. 9-cis-retinoic acid modulates the oligomeric state of the retinoid X receptor. (1995) (45)
- Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice. (2011) (45)
- Lipoprotein Lipase and Its Regulators: An Unfolding Story (2020) (45)
- Electric Pulse Stimulation of Myotubes as an In Vitro Exercise Model: Cell-Mediated and Non-Cell-Mediated Effects (2015) (44)
- Genome-wide analysis of PPARalpha activation in murine small intestine. (2007) (44)
- Hepatic Sel1L‐Hrd1 ER‐associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH (2018) (44)
- Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not? (2021) (44)
- PPARα‐dependent induction of the energy homeostasis‐regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: Potential role in starvation adaptation (2007) (44)
- Auto-silencing by the retinoid X receptor. (1998) (41)
- Short-chain Fatty Acids Stimulate Angiopoietin-like 4 Synthesis In Human Colon Adenocarcinoma Cells By Activating Peroxisome Proliferator-activated Receptor Gamma (2015) (41)
- Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice (2018) (40)
- The Tetramerization Region of the Retinoid X Receptor Is Important for Transcriptional Activation by the Receptor* (1997) (40)
- Effects of fatty acids on gene expression: role of peroxisome proliferator-activated receptor α, liver X receptor α and sterol regulatory element-binding protein-1c (2002) (38)
- Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance. (2004) (38)
- ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract (2013) (38)
- Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells (2020) (37)
- Angiopoietin-like protein 4 is differentially regulated by glucocorticoids and insulin in vitro and in vivo in healthy humans. (2012) (36)
- Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity (2019) (36)
- Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. (2012) (36)
- Adipocyte Spliced Form of X-Box–Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis (2014) (35)
- Regulation of lipid metabolism via angiopoietin-like proteins (2005) (32)
- The DNA Binding Pattern of the Retinoid X Receptor Is Regulated by Ligand-dependent Modulation of Its Oligomeric State* (1997) (32)
- Deletion of the gene encoding G0/G1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice (2014) (31)
- Fasting-induced adipose factor/angiopoietin-like protein 4: a potential target for dyslipidemia? (2006) (31)
- Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase. (2012) (30)
- Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice[S] (2019) (30)
- Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion[S] (2013) (30)
- On the role of ligand in retinoid signaling: positive cooperativity in the interactions of 9-cis retinoic acid with tetramers of the retinoid X receptor. (1995) (30)
- A single day of high fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice. (2019) (30)
- Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. (2020) (29)
- Exercise training improves liver steatosis in mice (2015) (29)
- Transcriptional profiling reveals divergent roles of PPAR and PPAR / in regulation of gene expression in mouse liver (2010) (29)
- The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice (2018) (29)
- LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux. (2010) (29)
- The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice (2018) (28)
- HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation. (2020) (28)
- PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference (2014) (27)
- Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue (2020) (26)
- Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury. (2012) (25)
- Mannose-Binding Lectin Is Required for the Effective Clearance of Apoptotic Cells by Adipose Tissue Macrophages During Obesity (2014) (25)
- How the COVID-19 pandemic highlights the necessity of animal research (2020) (24)
- Induction of Cardiac Angptl 4 by Dietary Fatty Acids Is Mediated by Peroxisome Proliferator-Activated Receptor / and Protects Against Fatty Acid – Induced Oxidative Stress (2010) (24)
- PPARγ activity in subcutaneous abdominal fat tissue and fat mass gain during short-term overfeeding (2006) (24)
- Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue. (2018) (23)
- Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans12[S] (2013) (23)
- Plasma mannose-binding lectin is stimulated by PPARα in humans. (2012) (22)
- A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα-mediated upregulation of SREBP-2 target genes in the liver. (2011) (22)
- Promoter Rearrangements Cause Species-specific Hepatic Regulation of the Glyoxylate Reductase/Hydroxypyruvate Reductase Gene by the Peroxisome Proliferator-activated Receptor α* (2005) (22)
- Industrial Trans Fatty Acids Stimulate SREBP2‐Mediated Cholesterogenesis and Promote Non‐Alcoholic Fatty Liver Disease (2019) (21)
- Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue (2017) (21)
- Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism (2021) (20)
- The Effects of Long‐ or Medium‐Chain Fat Diets on Glucose Tolerance and Myocellular Content of Lipid Intermediates in Rats (2011) (20)
- Regulation of lipid droplet homeostasis by hypoxia inducible lipid droplet associated HILPDA. (2020) (19)
- Muscle-specific inflammation induced by MCP-1 overexpression does not affect whole-body insulin sensitivity in mice (2015) (19)
- Regulation of nutrient metabolism and inflammation. (2010) (19)
- Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology (2014) (19)
- Design guidelines for the development of digital nutrigenomics learning material for heterogeneous target groups. (2007) (18)
- Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages (2022) (17)
- Hepatic genome-wide expression of lipid metabolism in diet-induced obesity rats treated with cocoa polyphenols (2015) (17)
- Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects (2018) (16)
- No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults (2019) (15)
- Hypoxia-inducible lipid droplet-associated induces DGAT1 and promotes lipid storage in hepatocytes (2021) (15)
- Peroxisome proliferator-activated receptor alpha controls hepatic heme biosynthesis through ALAS1. (2009) (15)
- Kupffer Cells Promote Hepatic Steatosis Via Interleukin-1 (cid:1) –Dependent Suppression of Peroxisome Proliferator-Activated Receptor (cid:2) Activity (2010) (15)
- Global profiling of the muscle metabolome: method optimization, validation and application to determine exercise-induced metabolic effects (2015) (14)
- Effects of fatty acids on gene expression: role of peroxisome proliferator-activated receptor alpha, liver X receptor alpha and sterol regulatory element-binding protein-1c. (2002) (14)
- ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota. (2017) (14)
- Multiple effects of cold exposure on livers of male mice. (2018) (14)
- MicroRNA‐204‐5p modulates mitochondrial biogenesis in C2C12 myotubes and associates with oxidative capacity in humans (2020) (14)
- MicroRNA‐382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells (2018) (14)
- Angiopoietin-Like Protein 4 and Postprandial Skeletal Muscle Lipid Metabolism in Overweight and Obese Prediabetics. (2016) (13)
- ANGPTL3 as therapeutic target (2021) (13)
- Feeding Angptl4−/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites[S] (2017) (12)
- Peroxisome Proliferator-Activated Receptor-- Null Mice Have Increased White Adipose Tissue Glucose Utilization , GLUT 4 , and Fat Mass : Role in Liver and Brain (2006) (11)
- Angiopoietin-Like Proteins and Lipid Metabolism (2009) (10)
- Metabolic responses to mild cold acclimation in type 2 diabetes patients (2021) (9)
- Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα (2019) (9)
- PPARs: Important Regulators in Metabolism and Inflammation (2010) (9)
- Correction: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance (2015) (8)
- Retinoid X receptor a forms tetramers in solution (8)
- PPARS and Obesity (2007) (7)
- The Interleukin 1 receptor antagonist is a direct target gene of PPAR in (2011) (7)
- Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation (2018) (7)
- Regulation of Lipogenic Genes in Obesity (2006) (6)
- Probing metabolic memory in the hepatic response to fasting. (2020) (6)
- Transcriptomic signature of fasting in human adipose tissue. (2020) (6)
- Short-term cooling increases serum angiopoietin-like 4 levels in healthy lean men. (2017) (6)
- Bypassing the LDL Receptor in Familial Hypercholesterolemia. (2020) (5)
- Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers (2020) (5)
- The PPARγ ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARγ in the subcutaneous adipose tissue (2008) (5)
- Lipoprotein lipase in mouse kidney: effects of nutritional status and high-fat diet. (2019) (5)
- Bioactivity screening and mass spectrometric confirmation for the detection of PPARδ agonists that increase type 1 muscle fibres (2013) (5)
- 12: IL-37 protects against obesity-induced inflammation and insulin resistance (2013) (5)
- Mild intermittent hypoxia exposure induces metabolic and molecular adaptations in men with obesity (2021) (5)
- Triglyceride Metabolism under Attack. (2017) (5)
- Effects of fatty acids on gene expression : role of peroxisome proliferator-activated receptor α , liver X receptor α and sterol regulatory element-binding protein-1 c (2002) (4)
- The Genetics of Dyslipidemia--When Less Is More. (2016) (4)
- Peroxisome Proliferator-activated Receptor Regulates Expression of the Anti-lipolytic G-protein-coupled Receptor (2009) (4)
- The roles of PPARα and PPARβ/δ in liver: Dietary versus endogenous fat sensor (2008) (4)
- Erratum: How the COVID-19 pandemic highlights the necessity of animal research (Current Biology (2020) 30(18) (R1014–R1018), (S0960982220311842), (10.1016/j.cub.2020.08.030)) (2020) (4)
- Saturated fatty acids and snoRNAs: partners in crime. (2011) (4)
- Long-lost friend is back in the game (2021) (4)
- Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue (2022) (3)
- A lipase fusion feasts on fat (2020) (3)
- Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice (2021) (3)
- Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome (2022) (3)
- Effects of dietary l-carnitine supplementation on the response to an inflammatory challenge in mid-lactating dairy cows: Hepatic mRNA abundance of genes involved in fatty acid metabolism. (2021) (2)
- Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology (2014) (2)
- Energy-sensing Factors Coactivator Peroxisome Proliferator-activated Receptor (cid:1) Coactivator 1- (cid:2) (PGC-1 (cid:2) ) and AMP-activated Protein Kinase Control Expression of Inflammatory Mediators in Liver INDUCTION OF INTERLEUKIN 1 RECEPTOR ANTAGONIST (2020) (2)
- The impact of fasting on adipose tissue metabolism. (2022) (2)
- Hypoxia-Inducible Lipid Droplet-Associated Interacts with DGAT1 to Promote Lipid Storage in Hepatocytes (2020) (2)
- HILPDA uncouples lipid storage in adipose tissue macrophages from inflammation and metabolic dysregulation (2019) (2)
- RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes (2021) (2)
- PPARγ activation promotes infiltration of alternatively activated macrophages into adipose tissue (2008) (2)
- How the COVID-19 pandemic highlights the necessity of animal research (2020) (2)
- Macrophages take up VLDL-sized emulsion particles through caveolae-mediated endocytosis and excrete part of the internalized triglycerides as fatty acids (2022) (2)
- The impact of PPARα activation on whole genome gene expression in human precision cut liver slices (2015) (2)
- Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice (2022) (2)
- Global testing of shifts in metabolic phenotype (2018) (2)
- ' s personal copy Peroxisome Proliferator-Activated Receptor α Controls Hepatic Heme Biosynthesis Through ALAS 1 (2009) (2)
- ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy (2022) (2)
- Regulation of endoplasmic reticulum-mitochondria contacts and mitochondrial dynamics by Sel1L-Hrd1 ERAD during thermogenesis (2020) (1)
- Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation (2018) (1)
- Hepatic ADTRP overexpression does not influence lipid and glucose metabolism. (2021) (1)
- Effects of high‐fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring (2015) (1)
- Hypoxia-inducible lipid droplet-associated interacts with DGAT1 and promotes lipid storage in hepatocytes (2020) (1)
- Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells (2020) (1)
- Retraction notice to “Peroxisome proliferator-activated receptor α controls hepatic heme biosynthesis through ALAS1” J. Mol. Biol. 388/2 (2010) 225–238. (2010) (1)
- Sulfonylureas and Glinides Exhibit PPARγ Activity: A Combined Virtual Screening and Biological Assay Approach* (2006) (1)
- Caveolae mediated endocytosis of VLDL particles in macrophages requires NPC1 and STARD3 for further lysosomal processing (2021) (1)
- SULFONYLUREAS AND GLINIDES AS NEW PPARγ AGONISTS: VIRTUAL SCREENING AND BIOLOGICAL ASSAYS (2007) (1)
- Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colonocytes by selective PPARγ modulation (2013) (1)
- [739] THE ROLE OF PPAR-ALPHA AND PPAR-GAMMA IN OBESITY-INDUCED HEPATIC INFLAMMATION (2007) (1)
- Angptl4 Protects Against Severe Pro-Inflammatory Effects of Dietary Saturated Fat by Inhibiting LPL-Dependent Uptake of Fatty Acids in Mesenteric Lymph Node Macrophages (2010) (1)
- A Diurnal Rhythm In Brown Adipose Tissue Causes Rapid Clearance Of Plasma Lipids At Wakening (2019) (1)
- Primary tumor–derived systemic nANGPTL4 inhibits metastasis (2022) (1)
- Dropping liver fat droplets (2009) (1)
- Fight fat with DGAT1 (2011) (1)
- The PPAR g ligand rosiglitazone influences triacylglycerol metabolism in non-obese males , without increasing the transcriptional activity of PPAR g in the subcutaneous adipose tissue (2008) (1)
- Author response: ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure (2015) (1)
- In fl ammation increases plasma angiopoietin-like protein 4 in patients with the metabolic syndrome and type 2 diabetes (2014) (1)
- Reply: (2010) (0)
- Peroxisome Proliferator-Activated Receptor β/δ (PPARβ/δ) but Not PPARα Serves as a Plasma Free Fatty Acid Sensor in Liver (2010) (0)
- Detailed transcriptomics analysis of the effect of dietary fatty acids on gene regulation in the murine heart. (2012) (0)
- Sel1L is Indispensable for Mammalian ERAD, ER Homeostasis and Survival (2013) (0)
- target groups nutrigenomics learning material for heterogeneous Design guidelines for the development of digital (2007) (0)
- Effects of acute exercise on gene expression in exercising and non-exercising human skeletal muscle (2012) (0)
- Probing the role of peroxisome proliferator-activated receptor alpha (PPAR??) in the small intestine (2006) (0)
- The effect of Angptl4 on atherosclerosis development: exploration of Angptl4 as a novel putative therapeutic target for atherosclerosis (2008) (0)
- PS10 - 1. Fatty acid inducible myokine ANGPTL4 governs the lipid metabolic response to acute exercise (2013) (0)
- Exploring the human PPAR alpha dependent transcriptome in primary human hepatocytes (2008) (0)
- Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism (2022) (0)
- Comparative analysis of gene regulation by the transcription factor PPARα_human (2009) (0)
- Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4 (2022) (0)
- Feedback regulation of cardiac fatty acid uptake is mediated by Angptl4 (2008) (0)
- PS1 - 7. Long-term cold exposure down-regulates Angptl4 expression in brown adipocytes (2013) (0)
- PS10 - 4. Exercise training lowered hepatic fat in a steatotic mice model (2013) (0)
- Fasting-induced adipose factor/angiopoietin-like protein 4 as an adipokine (2011) (0)
- Transcriptomic analysis reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes (2021) (0)
- Regulation of Angiopoietin-like 4 and Lipoprotein Lipase in Human Subcutaneous Adipose Tissue (2018) (0)
- Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα (2019) (0)
- PS14 - 72. The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (0)
- CD1d-restricted NKT cell function prevents insulin resistance in lean mice, and is regulated by adipocytes and is regulated by adipocytes (2012) (0)
- PS4 - 6. Hepatic vanin-1 is highly induced by PPAR-alpha and a key mediator of hepatic lipid metabolism in the fasted state (2013) (0)
- BROWN ADIPOSE TISSUE INTERNALIZES FATTY ACIDS BY SELECTIVE DELIPIDATION OF LIPOPROTEINS RATHER THAN BY UPTAKE OF LIPOPROTEINS (2014) (0)
- ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract (2013) (0)
- Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human] (2016) (0)
- Cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. (2015) (0)
- Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects (2018) (0)
- athletesvs. single bouts of prolonged cycling in elite Enhanced plasma IL-6 and IL-1ra responses to (2015) (0)
- CORRECTIONS (2003) (0)
- PP016-SUN POLYUNSATURATED LONG CHAIN FATTY ACIDS STRONGLY INDUCE ANGPTL4 IN HUMANS (2012) (0)
- Erratum: Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 5, (E582-E591) doi:10.1073/pnas.1318114111) (2014) (0)
- Adipose tissue failure signals the evolution of hepatic steatosis towards nonalcoholic steatohepatitis (NASH) in the C57BL/6 DIET-induced obesity mouse model (2008) (0)
- Physiological determinants of plasma Angptl4 in humans (2008) (0)
- PS15 - 75. Mannose Binding Lectin is required for the effective clearance of apoptotic cells by adipose tissue macrophages during obesity (2012) (0)
- mRNA profiling reveals divergent roles of PPARa and PPARß/d in regulating mouse liver gene expression (PPARb/d samples) (2009) (0)
- Expression of PPAR mRNA and protein levels in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD) (2006) (0)
- PS4 - 1. Hilpda is a novel PPAR target involved in hepatic lipid metabolism (2013) (0)
- Peroxisome Proliferator Activated Receptor Alpha Coordinates Intermediary Metabolism During Fasting (2002) (0)
- humansduring prolonged moderate-intensity exercise in Suppressing lipolysis increases interleukin-6 at rest (2015) (0)
- Elevated Free Fatty Acids Caloric Restriction and Exercise Increase Plasma ANGPTL 4 Levels in Humans (2009) (0)
- Liver X receptor beta is the dominant LXR subtype in skeletal muscle (2010) (0)
- Adipocyte XBP1s regulates systemic insulin sensitivity by modulating adiponectin multimerization (2013) (0)
- Global profiling of the muscle metabolome: method optimization, validation and application to determine exercise-induced metabolic effects (2014) (0)
- Peroxisome Proliferator-Activated Receptor (cid:1) / (cid:2) (PPAR (cid:1) / (cid:2) ) but Not PPAR (cid:3) Serves as a Plasma Free Fatty Acid Sensor in Liver (cid:1) † (2009) (0)
- 2 PPAR Research increased risk of developing cardiovascular disease ( CVD ) and type II diabetes (2006) (0)
- Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity (2019) (0)
- Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD. Commentary (2007) (0)
- The ER-Associated Degradation Adapter Protein Sel1L Regulates Triglyceride Metabolism via Lipoprotein Lipase (2015) (0)
- 97 ADIPOSE TISSUE FAILURE SIGNALS THE EVOLUTION OF HEPATIC STEATOSIS TOWARDS NONALCOHOLIC STEATOHEPATITIS (NASH) IN THE C57BL/6 HFD-INDUCED OBESITY MOUSE MODEL (2008) (0)
- PS15 - 74. CD1d-restricted NKT cell function prevents insulin resistance in lean mice, and is regulated by adipocytes (2012) (0)
- Hilpda Deficiency Reduces Lipid Storage In Adipose Tissue Macrophages Without Affecting Inflammation And Metabolic Dysregulation (2019) (0)
- Tu-P8:331 Angiopoietin-like proteins 3 and 4: Important regulators of plasma lipoprotein metabolisms (2006) (0)
- exercise-induced muscle damage Cellular adaptation to repeated eccentric (2015) (0)
- Modulating the gut microbiota by dietary guar gum protects against diet-induced obesity but promotes non-alcoholic steatohepatitis in mice (2017) (0)
- PS3 - 14. The effect of the exercise-induced muscle secretome on liver gene expression (2012) (0)
- Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers (2020) (0)
- Title Angiopoietin-like 4 : a decade of research (2017) (0)
- Angptl4 Hypomorphic Mice Expressing Truncated Angptl4 Exhibit Lymphadenopathy And Mild Chylous Ascites Upon High Fat Feeding (2019) (0)
- Detailed transcriptomics analysis of the effect of the PPARalpha agonist Wy14,643 on gene regulation in the murine heart (2012) (0)
- in mouse liver in regulation of gene expression δ / β and PPAR α PPARprofiling reveals divergent roles of (2015) (0)
- Toll-like receptors 2 and 4 control adaptive β-cell expansion in diet-induced obesity (2019) (0)
- Global testing of shifts in metabolic phenotype (2018) (0)
- The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (0)
- Effect PPARb/d knockout in white adipose tissue (2007) (0)
- PPAR γ REGULATES EXPRESSION OF THE ANTI-LIPOLYTIC G-PROTEIN-COUPLED RECEPTOR 81 (GPR81/Gpr81)* (2009) (0)
- ER-associated degradation is required for the maintenance of β cell identity via TGFβ signaling (2020) (0)
- The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice (2018) (0)
- PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation (2022) (0)
- response to acute resistance exercise factors in human skeletal muscle both at rest and in Aging alters gene expression of growth and remodeling (2015) (0)
- We-S16:3 Soy and impact on peroxisome proliferator activated receptors (2006) (0)
- Eicosapentaenoic acid improves metabolic switching in human myotubes (2010) (0)
- resistance exercise training responses interleukin-15 receptor genetic variation with Association of interleukin-15 protein and (2015) (0)
- PS7 - 38. Effects of acute endurance exercise on gene expression in skeletal muscle (2011) (0)
- Stabilizing lipoprotein lipase1 (2009) (0)
- Effects of mixed exercise training on gene expression in human skeletal muscle (2013) (0)
- muscleexpression after acute exercise in human skeletal Time course of proteolytic, cytokine, and myostatin (2015) (0)
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What Schools Are Affiliated With Sander Kersten?
Sander Kersten is affiliated with the following schools:
