Sandra Demaria
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Immunology
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Biology
Sandra Demaria's Degrees
- PhD Immunology Stanford University
- Masters Biology University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
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(Suggest an Edit or Addition)Sandra Demaria's Published Works
Published Works
- The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. (2015) (1875)
- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody (2009) (1267)
- Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. (2004) (1107)
- Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199. (2014) (1004)
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity (2017) (999)
- Combining radiotherapy and cancer immunotherapy: a paradigm shift. (2013) (857)
- Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. (2005) (856)
- Systemic effects of local radiotherapy. (2009) (793)
- Using immunotherapy to boost the abscopal effect (2018) (654)
- Consensus guidelines for the detection of immunogenic cell death (2014) (634)
- An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non–Small Cell Lung Cancer (2013) (581)
- Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells1 (2008) (562)
- Role of Local Radiation Therapy in Cancer Immunotherapy. (2015) (511)
- Radiotherapy induces responses of lung cancer to CTLA-4 blockade (2018) (497)
- Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. (2015) (496)
- Consensus guidelines for the definition, detection and interpretation of immunogenic cell death (2020) (423)
- Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death (2014) (423)
- Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothe (2017) (408)
- Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape. (2017) (398)
- TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity. (2015) (388)
- Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers. (2019) (345)
- Combining radiotherapy and immunotherapy: a revived partnership. (2005) (337)
- Cancer and Inflammation: Promise for Biologic Therapy (2010) (319)
- Current clinical trials testing the combination of immunotherapy with radiotherapy (2016) (314)
- Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy. (2001) (294)
- Radiation as an immunological adjuvant: current evidence on dose and fractionation (2012) (280)
- Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. (2017) (270)
- Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect. (2018) (247)
- The convergence of radiation and immunogenic cell death signaling pathways (2012) (239)
- Radiation therapy to convert the tumor into an in situ vaccine. (2012) (239)
- Radiotherapy: Changing the Game in Immunotherapy. (2016) (239)
- Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy (2017) (233)
- Combinations of Immunotherapy and Radiation in Cancer Therapy (2014) (214)
- TGFβ1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo (2011) (210)
- Emerging Opportunities and Challenges in Cancer Immunotherapy (2016) (209)
- Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs (2018) (200)
- Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group (2016) (189)
- Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer (2012) (184)
- Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects. (2012) (181)
- Tumor mutational burden is a determinant of immune-mediated survival in breast cancer (2018) (168)
- Focal Irradiation and Systemic TGFβ Blockade in Metastatic Breast Cancer (2018) (163)
- Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain (2005) (159)
- The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-term Survival of Mice Bearing Established Invasive GL261 Gliomas (2006) (152)
- Paclitaxel-induced apoptosis and mitotic arrest assessed by serial fine-needle aspiration: implications for early prediction of breast cancer response to neoadjuvant treatment. (2000) (147)
- Role of T lymphocytes in tumor response to radiotherapy (2012) (146)
- Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells (2017) (144)
- Up-regulation of the Pro-inflammatory Chemokine CXCL16 is a Common Response of Tumor Cells to Ionizing Radiation (2010) (140)
- Cytosolic DNA Sensing in Organismal Tumor Control. (2018) (139)
- In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment. (2015) (139)
- Barriers to Radiation-Induced In Situ Tumor Vaccination (2017) (137)
- Synergy of Topical Toll-like Receptor 7 Agonist with Radiation and Low-Dose Cyclophosphamide in a Mouse Model of Cutaneous Breast Cancer (2012) (133)
- Current clinical trials testing combinations of immunotherapy and radiation. (2015) (130)
- Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system (2019) (129)
- Combination of radiotherapy and immune checkpoint inhibitors. (2015) (128)
- Toward Precision Radiotherapy for Use with Immune Checkpoint Blockers (2017) (126)
- Sensors of ionizing radiation effects on the immunological microenvironment of cancer (2007) (115)
- The path to a better biomarker: application of a risk management framework for the implementation of PD‐L1 and TILs as immuno‐oncology biomarkers in breast cancer clinical trials and daily practice (2020) (108)
- Invariant Natural Killer T Cells Regulate Breast Cancer Response to Radiation and CTLA-4 Blockade (2009) (90)
- Soluble beta 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease. (1994) (89)
- Exercise in Regulation of Inflammation-Immune Axis Function in Cancer Initiation and Progression. (2015) (86)
- SnapShot: CGAS-STING Signaling (2018) (86)
- Immunogenic Subtypes of Breast Cancer Delineated by Gene Classifiers of Immune Responsiveness (2016) (81)
- The Optimal Partnership of Radiation and Immunotherapy: from Preclinical Studies to Clinical Translation (2014) (79)
- Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? (2021) (68)
- TREX1 dictates the immune fate of irradiated cancer cells (2017) (67)
- Radiotherapy Enhances Antitumor Effect of Anti-CD137 Therapy in a Mouse Glioma Model (2010) (66)
- CD73 Blockade Promotes Dendritic Cell Infiltration of Irradiated Tumors and Tumor Rejection (2020) (63)
- Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control. (2021) (63)
- Immune recognition of irradiated cancer cells (2017) (60)
- Trial Watch: Immunotherapy plus radiation therapy for oncological indications (2016) (60)
- Local control by radiotherapy: is that all there is? (2008) (60)
- Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer (2020) (60)
- Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking? (2016) (60)
- Select forms of tumor cell apoptosis induce dendritic cell maturation (2005) (60)
- Trial watch: Immune checkpoint blockers for cancer therapy (2017) (59)
- The Future of Radiobiology. (2018) (57)
- The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group (2021) (54)
- Future perspectives in melanoma research (2016) (54)
- Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group (2020) (54)
- Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple-negative breast cancer patients after neoadjuvant chemotherapy (2019) (54)
- HLA-A2-Restricted CD8+-Cytotoxic-T-Cell Responses to Novel Epitopes in Mycobacterium tuberculosis Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase (2004) (53)
- Exercise reduces immune suppression and breast cancer progression in a preclinical model (2020) (53)
- Physical association between the CD8 and HLA class I molecules on the surface of activated human T lymphocytes. (1988) (51)
- Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple-negative breast cancer patients after neoadjuvant chemotherapy. (2019) (50)
- Tumor infiltrating lymphocytes (TILs) improve prognosis in patients with triple negative breast cancer (TNBC) (2015) (49)
- The origin and fate of β2m-free MHC class I molecules induced on activated T cells (1992) (49)
- Radiotherapy Effects on Anti-Tumor Immunity: Implications for Cancer Treatment (2013) (48)
- Emerging biomarkers for the combination of radiotherapy and immune checkpoint blockers. (2017) (43)
- Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014 (2013) (42)
- Soluble HLA proteins with bound peptides are released from the cell surface by the membrane metalloproteinase. (2000) (37)
- Invariant NKT Cells as Novel Targets for Immunotherapy in Solid Tumors (2012) (37)
- Radiation-Induced Long Noncoding RNAs in a Mouse Model after Whole-Body Irradiation (2018) (37)
- Murine monoclonal antibodies as probes for the phenotypical, functional, and molecular analysis of a discrete peripheral blood lymphocyte population exerting natural killer activity in vitro. (1985) (35)
- Abscopal Responses in Metastatic Non-Small Cell Lung Cancer (NSCLC) Patients Treated on a Phase 2 Study of Combined Radiation Therapy and Ipilimumab: Evidence for the In Situ Vaccination Hypothesis of Radiation (2015) (34)
- Expression of cancer testis antigens in human BRCA-associated breast cancers: potential targets for immunoprevention? (2011) (34)
- Abstract S1-03: Pooled individual patient data analysis of stromal tumor infiltrating lymphocytes in primary triple negative breast cancer treated with anthracycline-based chemotherapy (2016) (34)
- Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment (2013) (34)
- Effects of chemoradiation on tumor-host interactions: the immunologic side. (2008) (33)
- The TLR7 agonist imiquimod as an adjuvant for radiotherapy-elicited in situ vaccination against breast cancer (2013) (32)
- Potentiating anti-tumor efficacy through radiation and sustained intratumoral delivery of anti-CD40 and anti-PDL1. (2020) (31)
- Tumor-In fi ltrating Lymphocytes and Prognosis : A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers (2019) (31)
- Stromal Tumor-infiltrating Lymphocytes in NRG Oncology/NSABP B-31 Adjuvant Trial for Early-stage HER2-positive Breast Cancer. (2019) (29)
- Baseline T cell dysfunction by single cell network profiling in metastatic breast cancer patients (2019) (29)
- The metalloproteinase-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection. (1998) (27)
- Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer (2020) (27)
- Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes (2014) (27)
- Densely ionizing radiation acts via the microenvironment to promote aggressive Trp53-null mammary carcinomas. (2014) (26)
- Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group (2020) (26)
- The need for a network to establish and validate predictive biomarkers in cancer immunotherapy (2017) (24)
- Emerging Technologies for Local Cancer Treatment (2020) (23)
- CD8+ T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy (2016) (23)
- Peptide-conformed beta2m-free class I heavy chains are intermediates in generation of soluble HLA by the membrane-bound metalloproteinase. (1999) (23)
- Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod (2019) (22)
- Increased density of ecto 5' nucleotidase antigen on leukemic T cells from patients with cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma. (1989) (22)
- Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade (2020) (22)
- CD8 and β2-microglobulin-free MHC class I molecules in T cell immunoregulationMHC class I molecules in T cell immunoregulation (1993) (22)
- Microarray analysis of miRNA expression profiles following whole body irradiation in a mouse model (2018) (21)
- Viral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant (2020) (21)
- Preventive Efficacy of a Tenofovir Alafenamide Fumarate Nanofluidic Implant in SHIV‐Challenged Nonhuman Primates (2020) (20)
- Radiation-induced Adaptive Response: New Potential for Cancer Treatment (2020) (20)
- Abscopal Response in Irradiated Patients: Results of a Proof of Principle Trial (2008) (19)
- The origin and fate of beta 2m-free MHC class I molecules induced on activated T cells. (1992) (19)
- The role of radiotherapy in the age of immunotherapy (2021) (18)
- Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer (2022) (17)
- The Numbers of FoxP3+ Lymphocytes in Sentinel Lymph Nodes of Breast Cancer Patients Correlate With Primary Tumor Size but Not Nodal Status (2011) (17)
- PTEN at the interface of immune tolerance and tumor suppression (2017) (17)
- Activin A Promotes Regulatory T-cell–Mediated Immunosuppression in Irradiated Breast Cancer (2020) (17)
- Topical TLR 7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer (2012) (17)
- Multilocular Thymic Cyst with Follicular Lymphoid Hyperplasia in a Male Infected with HIV (1999) (17)
- 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine (2021) (16)
- Systems biology perspectives on the carcinogenic potential of radiation (2014) (16)
- Targeting Cancer Heterogeneity with Immune Responses Driven by Oncolytic Peptides. (2021) (16)
- Future perspectives in melanoma research “Melanoma Bridge”, Napoli, November 30th–3rd December 2016 (2017) (16)
- Soluble CD4 induces the binding of human immunodeficiency virus type 1 to cells via the V3 loop of glycoprotein 120 and specific sites in glycoprotein 41. (1996) (15)
- Radiotherapy Cooperates with IL15 to Induce Antitumor Immune Responses (2020) (15)
- Abstract 633: Inhibition of TGFβ as a strategy to convert the irradiated tumor into in situ individualized vaccine (2014) (14)
- Melanoma and immunotherapy bridge 2015 (2016) (13)
- LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cells (2021) (13)
- Cancer Immunotherapy Principles and Practice (2018) (13)
- Abstract S1-07: Prognostic value of tumor-infiltrating lymphocytes (TILs) in two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199 (2013) (13)
- 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts (2016) (12)
- Immune induction strategies to enhance responses to PD-1 blockade: lessons from the TONIC trial (2019) (11)
- 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two (2016) (11)
- Future of Radiation and Immunotherapy. (2020) (10)
- Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials (2020) (10)
- Results of a phase I–II study of adjuvant concurrent carboplatin and accelerated radiotherapy for triple negative breast cancer (2017) (10)
- Definition by CB12 monoclonal antibody of a differentiation marker specific for human monocytes and their bone marrow precursors. (1986) (9)
- Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer (2021) (9)
- Pilot Trial of Radiation Therapy and GM-CSF in Metastatic Cancer: Abscopal Responses (2012) (9)
- Unique changes in the TCR repertoire of tumor-infiltrating lymphocytes underlie the synergy of radiotherapy with CTLA-4 blockade (2014) (9)
- TREX1 is a checkpoint for innate immune sensing of DNA damage that fosters cancer immune resistance. (2017) (8)
- Cross-Talk of Breast Cancer Cells with the Immune System (2011) (8)
- Heavy Metal to Rock the Immune Infiltrate. (2017) (8)
- Understanding Responses to Stereotactic Body Radiotherapy and Pembrolizumab. (2018) (8)
- Adenosine regulates radiation therapy-induced anti-tumor immunity (2015) (8)
- Clinical trial evidence of the antitumor activity of topical imiquimod for breast cancer skin metastases. (2014) (8)
- Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention (2019) (7)
- Fine Needle Aspiration of Primary Pleomorphic Liposarcoma of the Breast (1999) (7)
- Immunogenic Cell Death Driven by Radiation-Impact on the Tumor Microenvironment. (2020) (7)
- Bathophenanthroline disulfonate and soluble CD4 as probes for early events of HIV type 1 entry. (1995) (6)
- Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non–small cell lung cancer (2022) (6)
- Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials (2020) (6)
- Intratumoral IL-15 potentiates radiation-induced anti-tumor immunity (2015) (6)
- Adenosine Regulates Radiation Therapy–Induced Anti-Tumor Immunity (2016) (6)
- Radiotherapy induces responsiveness of a resistant mammary carcinoma to PD-1 blockade (2014) (5)
- Activation of human CD8-positive T cells via the CD8/HLA class I complex. (1990) (5)
- Adenosine generation limits radiation-induced tumor immunogenicity by abrogating recruitment and activation of CD103+ DCs (2017) (4)
- Unique Changes in the TCR Repertoire of Tumor-Infiltrating Lymphocytes Underlie the Synergy of Radiation Therapy With CTLA-4 Blockade (2016) (4)
- CD8 and beta 2-microglobulin-free MHC class I molecules in T cell immunoregulation. (1993) (4)
- Abstract 536: NBTXR3 potentiate cancer-cell intrinsic interferon beta response to radiotherapy (2019) (4)
- Peptide loading of nascent MHC class I molecules. (2001) (4)
- Role of the crosstalk between CTLA-4 and NKG2D in the development of anti-CTLA-4 treatment strategies. (2013) (4)
- Exosomes shuttle TREX1-sensitive IFN-stimulatory dsDNA from irradiated cancer cells to dendritic cells (2018) (4)
- Towards an immunoscore for triple negative breast cancer (TNBC): lymphocytic infiltrate predicts outcome (2013) (4)
- Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts (2018) (3)
- Defining the role of the immune system in cancer treatment: highlights from the Immunochemotherapy Conference (2011) (3)
- ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels (2022) (3)
- The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018 (2019) (3)
- Functional and molecular characterization by the CB04 monoclonal antibody of a cell surface structure exerting C3-complement receptor activity (1985) (3)
- TGFβ and activin A control regulatory T cells in irradiated tumors (2015) (3)
- IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection (2020) (3)
- Subverting misconceptions about radiation therapy (2016) (3)
- Novel Combination of Toll-Like Receptor (TLR)-7 Agonist Imiquimod and Local Radiation Therapy in the Treatment of Metastatic Breast Cancer Involving the Skin or Chest Wall (2013) (3)
- Radiation therapy-induced remodeling of the tumor immune microenvironment. (2022) (3)
- Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts (2017) (3)
- The abscopal effect of local radiotherapy is induced by TGFβ blockade (2013) (3)
- Reduction of immature myeloid cells by treatment with all-trans-retinoic acid (ATRA) improves the immunotherapeutic effect of the combination of local radiation with CTLA-4 blockade (2004) (3)
- Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st–2nd, 2021 (2022) (2)
- Abstract B05: Adenosine generation limits the ability of radiation therapy to induce antitumor immunity by abrogating recruitment and activation of CD103+ DCs (2018) (2)
- Ionizing Radiation With An Endoplasmic Reticulum Stress-inducer Promotes Calreticulin Redistribution: A Marker Of Immunogenic Cell Death (2011) (2)
- Abstract 1395: Inhibition of transforming growth factor β (TGFβ) increases the therapeutic benefit of radiotherapy in a murine mammary tumor model (2010) (2)
- Abstract 2856: Unique changes in the TCR repertoire of tumor-infiltrating lymphocytes underlie the synergy of radiotherapy with CTLA-4 blockade (2015) (2)
- Mechanisms of synergy of radiotherapy and immunotherapy (2015) (2)
- Radiation Therapy Sensitizes a Poorly Immunogenic Breast Cancer to PD-1 Blockade (2014) (2)
- Fractionated but not single dose radiation releases key signals of in situ tumor vaccination (2014) (2)
- Extracellular Processing of MHC Class I Antigens (2004) (2)
- SP-0012: Abscopal responses in metastatic non-small cell lung cancer (NSCLC): a phase II study of combined radiotherapy and ipilimumab (2017) (2)
- Perspectives in melanoma: meeting report from the “Melanoma Bridge” (December 5th–7th, 2019, Naples, Italy) (2020) (2)
- Analysis by Monoclonal Antibodies of Cell Surface Structures Marking Discrete Steps of Cell Differentiation (1985) (2)
- The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-Term Survival of Mice Bearing Invasive GL261 Glioma (2005) (2)
- Therapeutic effect of local Interleukin-15 with radiotherapy in breast cancer. (2017) (2)
- CXCR6 and CXCL16 are expressed by breast cancer cells and may play a dual role in tumor progression. (2006) (2)
- Abstract 244: Abscopal responses in patients with refractory metastatic NSCLC treated with concurrent radiotherapy and CTLA-4 immune checkpoint blockade: evidence for the in situ vaccination hypothesis of radiotherapy (2015) (1)
- MTOR inhibition favors the differentiation of human in vitro-induced regulatory T cell through selective protein synthesis (2015) (1)
- Abstract 2493: Fractionated but not single dose radiation is an optimal adjuvant for in situ tumor vaccination (2015) (1)
- Research highlights: Immunotherapy. (2009) (1)
- 1INTREX1 as a gate-keeper of cGAS/STING-mediated activation of interferon type I in cancer cells treated with DNA-damaging agents (2018) (1)
- Novel combination of toll-like receptor (TLR)-7 agonist imiquimod and local radiotherapy in the treatment of breast cancer chest wall recurrences or skin metastases. (2013) (1)
- The Immunogenic Signature of Platinum and Radiation (2013) (1)
- Combination of local radiation with CTLA4 blockade: a new approach to the immunotherapy of breast cancer (2003) (1)
- THE LOW-AFFINITY Fc RECEPTOR FOR IgG RECOGNIZED BY MOAB AB8.28 IS CAPABLE OF TRANSDUCING ACTIVATION AND DEGRANULATORY SIGNALS IN LARGE GRANULAR LYMPHOCYTES (1987) (1)
- The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group (2021) (1)
- Tumor-Derived Exosomes as Modulators of Radiation-Induced Anti-Tumor Immunity (2016) (1)
- Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st–2nd, 2021 (2022) (1)
- Local radiotherapy and GM-CSF in metastatic cancer: lessons from a proof of principle trial (2016) (1)
- Synergy of radiation and immune therapy in tumor eradication (41.27) (2009) (1)
- The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group (2021) (1)
- Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd–3rd, 2020, Italy) (2021) (1)
- Anti-VISTA Antibody Increases Tumor-Specific T Cells and Prolongs Survival of Metastatic Carcinoma-Bearing Mice Treated With Radiation Therapy, Cytoxan, and PD-1 Blockade (2017) (1)
- Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule (2016) (1)
- Peritumoral IL-15 Potentiates Radiation-Induced Anti-Tumor Immunity (2016) (1)
- Definition by Murine Monoclonal Antibodies of Cell Surface Structures Exerting Fc- and C3Bi-Receptor Activity in Vivo (1985) (1)
- Immune Escape: Immunosuppressive Networks (2013) (1)
- Localizing radioimmunotherapy via nanochannel device for sustained intratumoral drug delivery for solid tumor treatment. (2019) (1)
- Evaluation of toll-like receptor (TLR)-7 agonist imiquimod applied topically to breast cancer chest wall recurrences or skin metastases. (2010) (1)
- Abstract 1820: Art1, an extracellular mono-ADP-ribosyltransferase, is upregulated in response to cellular stress and promotes lung cancer growth (2020) (1)
- Abstract OT2-1-02: Novel combination of toll-like receptor (TLR)-7 agonist imiquimod and local radiotherapy in the treatment of breast cancer chest wall recurrences or skin metastases (2013) (1)
- Abstract 4985: Radiation potentiates systemic anti-tumor immunity unleashed by a novel TLR9 agonist (SD-101) (2016) (0)
- Effect of Radiotherapy Variables on Circulating Effectors of Immune Response and Local Microbiome (2019) (0)
- PD-0761 Radiation-induced anti-tumor immunogenicity in pancreatic cancer cells – protons vs. X-rays (2021) (0)
- Abstract LB168: Blocking SIRPα on myeloid cells synergizes with radiation therapy in mouse breast cancer models (2021) (0)
- Preventive Efficacy of a Tenofovir Alafenamide Fumarate Nanofluidic Implant in SHIV‐Challenged Nonhuman Primates (Adv. Therap. 3/2021) (2021) (0)
- Abstract PR02: Identification of breast cancer neoantigens exposed by radiation therapy (2018) (0)
- TGFβ Superfamily Members Regulate Radiation-Induced In Situ Tumor Vaccination (2016) (0)
- Radiation Promotes a Dose–Response Induction of Immunogenic Cell Death (2013) (0)
- OC-0563: Hypoxia suppresses radiation-induced tumor immunogenicity in 3D breast cancer models (2020) (0)
- 560 Immunotherapeutic and antimetastatic activity of LTX-315 in preclinical models of ICI-resistant breast cancer (2021) (0)
- Visualizing Breast Cancer Cell Interaction With Tumor-Infiltrating Lymphocytes During Immunotherapy (2013) (0)
- Exploiting Breast Cancer Cells Stress Response to Ionizing Radiation to Improve the Effectiveness of Immunotherapy (2007) (0)
- Abstract 5020: Cooperative effects of programmed cell death-1 blockade and radiation in a model of a poorly immunogenic breast carcinoma (2014) (0)
- Peritumoral IL-15 Promotes Regional NK Activation and DC Licensing to Augment Radiation-Induced Anti-tumor Immunity (2017) (0)
- Prognostic implications of residual disease (RD) tumor-infiltrating lymphocytes (TIL) in triple negative breast cancer (TNBC) after neo-adjuvant chemotherapy (NAC). (2018) (0)
- AWARD NUMBER: W81XWH-13-1-0012 TITLE: Role of Activin A in Immune Response to Breast Cancer (2016) (0)
- Abstract 3329: Ionizing radiation modifies the molecular composition of exosomes derived from breast cancer cells (2015) (0)
- Radiation and Immune Checkpoints Blockade in Metastatic NSCLC (NCT03168464) (2020) (0)
- Circulating HMGB1 Levels Increase in Locally-Advanced Breast Cancer Patients Treated on a Protocol of Neoadjuvant Paclitaxel and Radiation (2013) (0)
- Activin A is upregulated by radiation in breast cancer cells and promotes conversion of CD4 T cells into regulatory T cells (2013) (0)
- Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system (2019) (0)
- Reviewers and Consultants Volume 43, 1999 (1999) (0)
- Subject Index, Volume 43, 1999 (1999) (0)
- VISTA Blockade Immunotherapy in a MULTI-Modal Approach to Triple Negative Breast Cancer (TNBC) in MICE and IMPACT on Microbiome (2019) (0)
- Local Radiotherapy Rescues Responsiveness to Anti-CD137 Immunotherapy in a Mouse Model of Advanced Breast Cancer. (2009) (0)
- Synergy Between Radiotherapy and Immunotherapy (2018) (0)
- Radiotherapy induces responses of lung cancer to CTLA-4 blockade (2018) (0)
- Combination of interleukin-15 and fractionated radiotherapy for cancer treatment (2014) (0)
- Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014 (2015) (0)
- The need for a network to establish and validate predictive biomarkers in cancer immunotherapy (2017) (0)
- Abstract IA04: Partnership of radiotherapy and immunotherapy: A new paradigm in cancer treatment (2015) (0)
- SP-0591: Radiotherapy for immunotherapy: optimizing the doses and fractionation (2016) (0)
- Abstract SY31-03: The future of combinations of immunomodulators with local radiation: toward a personalized immunotherapy approach (2016) (0)
- Immunomodulation with Radiation (2018) (0)
- Evaluating the Immunomodulatory Profile and Treatment Efficacy of Whole Lung Low-Dose Radiation Therapy (LDRT) in a Preclinical Model of Severe Viral Pneumonia (2021) (0)
- Successful clinical translation of preclinical combinations of radiation and immunotherapy (2013) (0)
- Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod (2019) (0)
- Abstract 2158: ART1 tumor expression mediates immune resistance in non-small cell lung cancer by elimination of P2 × 7R+ CD8 tissue resident memory T cells and conventional type I dendritic cells (2020) (0)
- 264 SIRPa blockade synergizes with radiation therapy in murine breast cancer models (2021) (0)
- Abstract 1309: Patient-derived tumor organoids as a platform to study radiation-exposed neoantigens (2022) (0)
- SP-0334: From local to abscopal: preclinical evidence that radiation dose and fractionation determine its synergy with immunotherapy (2018) (0)
- Pre-Clinical Assessment of CD137 (4–1BB)-Mediated Co-Stimulation in Combination With Whole Brain Radiation Therapy in the GL261 Glioma Model (2007) (0)
- Introduction to the Special BR-RIDGE Issue (2010) (0)
- 1117 A patient-derived tumor organoid platform to investigate radiation-induced neoantigen exposure (2022) (0)
- TGFβ superfamily members regulate radiation-induced anti-tumor immunity. (2017) (0)
- Macrophage-Targeting Agents to Stimulate Anti-Tumor Immunity Elicited by Radiation Therapy (2014) (0)
- Perspectives in melanoma: meeting report from the “Melanoma Bridge” (December 5th–7th, 2019, Naples, Italy) (2020) (0)
- Melanoma and immunotherapy bridge 2015 (2016) (0)
- 822 Local radiotherapy synergizes with tumor-specific TCR redirected T cells in the rejection of prostate cancer (2020) (0)
- Characterization of chemoradiation-induced changes in immune cells and targets for personalized therapy in locally advanced rectal cancer (LARC). (2019) (0)
- Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts (2017) (0)
- Radiation Therapy Exposes Immunogenic Mutations to the Immune System (2019) (0)
- SP-04: Combining Immunotherapy with Radiation Therapy (2012) (0)
- Abstract 4033: Adenosine regulates radiation therapy-induced antitumor immunity (2016) (0)
- Breast Cancer Cells Attracts Effector T Cells Radiation-Induced CXCL16 Release by (2008) (0)
- Contributor Index Volume 43, 1999 (1999) (0)
- Surviving mRNA splicing in oral cancer (2006) (0)
- Symposium with Proffered Papers: Novel approaches in tumour controlSP-0589: Molecular mechanisms of radiation-induced in situ tumor vaccination (2017) (0)
- Abstract 1648: Ionizing radiation switches the function of tumor-derived exosomes from messengers of tolerance to inducers of antitumor immunity (2016) (0)
- Radiation Improves Systemic Anti-Tumor Immunity Unleashed by a Novel TLR9 Agonist (SD-101) (2016) (0)
- Immune Effects of Conventional Cancer Therapeutics (2021) (0)
- The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 2021 (2022) (0)
- Effect of Radiotherapy Variables on Circulating Effectors of Immune Response (2020) (0)
- Something Old and Something New to Unleash the Power of Natural Killer Cells against Metastases (2021) (0)
- Multiplicity of Favorable Effects after Transforming Growth Factor-beta Inhibition in 4T1 Murine Mammary Tumors: Clinical Implications (2010) (0)
- Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd–3rd, 2020, Italy) (2021) (0)
- Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer (2022) (0)
- Paclitaxel Enhances the Immunogenic Signature of Radiation (2013) (0)
- Future perspectives in melanoma research (2016) (0)
- Systemic anti-cancer effects are triggered by local treatment with ionizing radiation and FLT3-Ligand in a syngeneic mouse model of mammary carcinoma (2002) (0)
- Phenotype of natural killer T cells infiltrating liver cancers (2009) (0)
- 459 NK cells activation and recruitment to irradiated tumors is increased in the presence of IL-15 (2020) (0)
- Ablative Radiation Fails to Induce Abscopal Responses in Breast Cancer (2019) (0)
- Shaping the Immune Landscape in Irradiated Breast Cancer Patients with Systemic TGF-β Blockade (2016) (0)
- 655 Pre-clinical studies of concomitant taxanes and ionizing radiation therapy: local and systemic anti-tumor effects (2004) (0)
- Abstract 4986: Regulation of radiation-induced in situ tumor vaccination by TGFβ superfamily members (2016) (0)
- The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 2021 (2022) (0)
- Abstract 2263: Characteristics of the interferon-stimulatory DNA cargo of exosomes produced by irradiated breast cancer cells (2020) (0)
- 35 INVITED Role of T-Lymphocytes for Tumour Response to Radiotherapy (2011) (0)
- Abstract PO-051: Radiation therapy enhances the presentation of phosphopeptides by MHC-I on cancer cells (2021) (0)
- KEYNOTE SPEAKER PRESENTATION (2015) (0)
- Quantitative assessment of mitophagy in irradiated cancer cells. (2023) (0)
- Future perspectives in melanoma research “Melanoma Bridge”, Napoli, November 30th–3rd December 2016 (2017) (0)
- P1-01-05: Conditioning by the Tumor Environment Turns Invariant Natural Killer T Cells into Negative Regulators of Anti-Tumor Immunity Elicited by Treatment. (2011) (0)
- Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer (2023) (0)
- Abstract B86: Radiation and TGFβ blockade bring back memories in metastatic breast cancer patients (2017) (0)
- Optimizing the Tumor Response to Ionizing Radiation and Immunotherapy by Blocking VEGF (2008) (0)
- Abstract IA29: Novel insights into the dose-dependency of radiation immunogenicity (2018) (0)
- 465 Radiotherapy and CTLA-4 blockade expand anti-tumor T cells differentiation states and cooperate with CD40 agonist to induce tumor rejection (2020) (0)
- Abstract P1-10-10: Tumor infiltrating lymphocytes (TILS) among high risk for recurrence breast cancer patients treated with tetrathimolybdate (TM) (2018) (0)
- Dendritic cells cross-presenting tumor-derived antigens are eliminated by invariant natural killer T (iNKT) cells, impairing development of anti-tumor immunity to a mouse carcinoma (2013) (0)
- Abstract 4987: Role of the PD-1/PDL-1 pathway in resistance of patients with metastatic breast cancer to treatment with radiotherapy and TGFβ neutralization (2016) (0)
- Abstract 1416: Peritumoral IL-15 potentiates radiation-induced anti-tumor immunity (2016) (0)
- Thoughts on the Cytopathologist and Cell Culture (1999) (0)
- Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts (2018) (0)
- Liver Metastasis Irradiation Can Restore Immunotherapeutic Responsiveness. (2021) (0)
- Abstract A21: Adenosine is a rheostat for radiation therapy-induced immune activation (2015) (0)
- Mechanisms of synergy of radiotherapy and immunotherapy (2015) (0)
- PTEN Signaling at the Tumor: Immune Interface (2017) (0)
- Expression of cancer testis (CT) antigens in human BRCA-associated breast cancers: Potential targets for immunoprevention? (2011) (0)
- Beta-Catenin Induces A Population of Radio-Resistant Alveolar Stem/Progenitors That Progress To Form Hormone-Independent Breast Tumors in Mice (2005) (0)
- Ionizing radiation modifies immune-related molecular profiles of tumor-derived exosomes (2015) (0)
- Increased Radiosensitivity In Vivo following Inhibition of Transforming Growth Factor Beta in Murine Model of Triple Negative Breast Cancer (2011) (0)
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What Schools Are Affiliated With Sandra Demaria?
Sandra Demaria is affiliated with the following schools: