Sandro Santagata
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Sandro Santagata's Degrees
- Bachelors Computer Science University of California, Berkeley
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Why Is Sandro Santagata Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sandro Santagata is an associate professor at Harvard Medical School and a physician-scientist at Brigham and Women’s Hospital where he practices neuropathology. His research focuses on precision medicine in cancer biology.
Sandro Santagata's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015) (727)
- Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. (2011) (643)
- Copper induces cell death by targeting lipoylated TCA cycle proteins (2022) (638)
- HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers (2012) (616)
- Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations (2013) (497)
- Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (439)
- Partial V(D)J Recombination Activity Leads to Omenn Syndrome (1998) (430)
- A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas (2005) (396)
- Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations (2010) (394)
- Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy (2013) (375)
- G-Protein Signaling Through Tubby Proteins (2001) (368)
- Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas (2014) (364)
- JAGGED1 Expression Is Associated with Prostate Cancer Metastasis and Recurrence (2004) (353)
- Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes (2018) (328)
- V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. (2001) (325)
- The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy (2014) (293)
- High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer (2011) (276)
- BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications (2011) (264)
- Mechanisms and therapeutic implications of hypermutation in gliomas (2020) (256)
- Classifying human brain tumors by lipid imaging with mass spectrometry. (2012) (245)
- Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State (2013) (243)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- The Homeodomain Region of Rag-1 Reveals the Parallel Mechanisms of Bacterial and V(D)J Recombination (1996) (218)
- Implication of tubby proteins as transcription factors by structure-based functional analysis. (1999) (205)
- Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery (2014) (203)
- Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors (2013) (203)
- Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma. (2016) (202)
- Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis (2014) (191)
- MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism (2016) (185)
- Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. (2016) (183)
- A HIF1-alpha Regulatory Loop Links Hypoxiaand Mitochondrial Signals in Pheochromocytomas (2005) (181)
- Taxonomy of breast cancer based on normal cell phenotype predicts outcome. (2014) (180)
- Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1 (2013) (180)
- Embryonic Stem Cell Transcription Factor Signatures in the Diagnosis of Primary and Metastatic Germ Cell Tumors (2007) (177)
- FokI requires two specific DNA sites for cleavage. (2001) (176)
- Phase II Study of Protracted Daily Temozolomide for Low-Grade Gliomas in Adults (2009) (158)
- Mitochondrial metabolism promotes adaptation to proteotoxic stress (2019) (158)
- Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer (2020) (139)
- Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections. (2011) (136)
- Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway (2010) (135)
- Using the heat-shock response to discover anticancer compounds that target protein homeostasis. (2011) (134)
- Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide (2018) (133)
- Genomic landscape of high-grade meningiomas (2017) (132)
- Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. (2012) (128)
- Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02. (2014) (127)
- Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma (2020) (127)
- The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2 (1999) (120)
- Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma (2014) (119)
- Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging (2013) (117)
- Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells (2013) (116)
- Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas (2016) (113)
- Label-Free Neurosurgical Pathology with Stimulated Raman Imaging. (2016) (106)
- HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models (2014) (96)
- BAP1 mutations in high-grade meningioma: implications for patient care. (2017) (95)
- Radiographic prediction of meningioma grade by semantic and radiomic features (2017) (93)
- Rapid Selection of Cyclic Peptides that Reduce α-Synuclein Toxicity in Yeast and Animal Models (2009) (92)
- Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer (2020) (88)
- Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma. (2014) (85)
- Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors (2016) (84)
- Genomic landscape of intracranial meningiomas. (2016) (83)
- Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. (2011) (79)
- The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination. (1999) (79)
- Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema (2018) (79)
- Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy. (2016) (78)
- Landscape of Genomic Alterations in Pituitary Adenomas (2016) (78)
- Mass spectrometry imaging as a tool for surgical decision-making. (2013) (78)
- An update on the CNS manifestations of neurofibromatosis type 2 (2019) (73)
- ARID1A and TERT promoter mutations in dedifferentiated meningioma. (2015) (71)
- Mutations in Conserved Regions of the Predicted RAG2 Kelch Repeats Block Initiation of V(D)J Recombination and Result in Primary Immunodeficiencies (2000) (68)
- A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma. (2015) (67)
- N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains. (2000) (66)
- Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome (2015) (63)
- MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation (2015) (63)
- Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors (2017) (63)
- DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome (2018) (62)
- Inhibiting HSP90 to treat cancer: a strategy in evolution. (2012) (62)
- Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging (2019) (62)
- The genetic and biochemical basis of Omenn syndrome (2000) (59)
- ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma. (2016) (58)
- Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. (2014) (58)
- Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5 (2014) (58)
- Sporadic hemangioblastomas are characterized by cryptic VHL inactivation (2014) (57)
- Eastern Equine Encephalitis in Children, Massachusetts and New Hampshire,USA, 1970–2010 (2013) (57)
- Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy (2021) (56)
- HSF1 phase transition mediates stress adaptation and cell fate decisions (2019) (55)
- Updates in prognostic markers for gliomas. (2018) (55)
- Omenn Syndrome: A Disorder of Rag1 and Rag2 Genes (1999) (55)
- MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging (2021) (53)
- Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas (2014) (53)
- Cross-reactivity of the BRAF VE1 antibody with epitopes in axonemal dyneins leads to staining of cilia (2015) (52)
- Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma (2018) (51)
- Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor (2017) (49)
- A molecularly integrated grade for meningioma (2021) (47)
- Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations (2019) (47)
- Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors (2017) (46)
- Rapid Selection of Cyclic Peptides that Reduce Alpha-Synuclein Toxicity in Yeast and Animal Models (2009) (46)
- Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic (2020) (45)
- Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Glioblastoma (2019) (44)
- The Effect of Me2+ Cofactors at the Initial Stages of V(D)J Recombination* (1998) (44)
- Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers (2016) (44)
- The impact of histopathology and NAB2–STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma (2018) (42)
- Comparative Analysis of Germ Cell Transcription Factors in CNS Germinoma Reveals Diagnostic Utility of NANOG (2006) (42)
- Rapid MALDI mass spectrometry imaging for surgical pathology (2019) (42)
- Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making. (2015) (42)
- Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. (2017) (42)
- Definition of Minimal Domains of Interaction Within the Recombination-Activating Genes 1 and 2 Recombinase Complex1 (2000) (41)
- Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma. (2015) (41)
- CRX Is a Diagnostic Marker of Retinal and Pineal Lineage Tumors (2009) (41)
- Rapid discrimination of pediatric brain tumors by mass spectrometry imaging (2018) (40)
- Treatment of brain metastases in the modern genomic era (2017) (40)
- Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. (2015) (39)
- Localized metabolomic gradients in patient-derived xenograft models of glioblastoma. (2019) (39)
- The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection (2014) (38)
- The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution (2021) (38)
- Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors (2021) (37)
- Molecular Cloning and Characterization of a Mouse Homolog of Bacterial ClpX, a Novel Mammalian Class II Member of the Hsp100/Clp Chaperone Family* (1999) (34)
- Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade. (2018) (34)
- Multiplex amplification coupled with COLD-PCR and high resolution melting enables identification of low-abundance mutations in cancer samples with low DNA content. (2011) (33)
- Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer (2019) (31)
- Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours (2016) (31)
- Intraoperative Magnetic Resonance Imaging in Intracranial Glioma Resection: A Single-Center, Retrospective Blinded Volumetric Study. (2015) (30)
- Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma (2019) (29)
- A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers. (2020) (29)
- Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy. (2016) (29)
- Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation (2019) (28)
- DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues (2012) (28)
- Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC–ESI-MS–MS (2015) (26)
- Frequent inactivating mutations of the PBAF complex gene PBRM1 in meningioma with papillary features (2020) (24)
- Activity of PD-1 blockade with Nivolumab among patients with recurrent atypical/anaplastic meningioma: Phase II trial results. (2021) (24)
- Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling (2017) (23)
- Artifacts to avoid while taking advantage of top‐down mass spectrometry based detection of protein S‐thiolation (2014) (23)
- Checkpoint inhibition in meningiomas. (2016) (22)
- MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
- Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer (2021) (22)
- Response and Mechanisms of Resistance to Larotrectinib and Selitrectinib in Metastatic Undifferentiated Sarcoma Harboring Oncogenic Fusion of NTRK1 (2020) (22)
- Normal cell phenotypes of breast epithelial cells provide the foundation of a breast cancer taxonomy (2014) (21)
- Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function (2022) (20)
- Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR (2021) (19)
- Atypical presentation of cerebral schistosomiasis four years after exposure to Schistosoma mansoni☆ (2014) (19)
- Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas (2022) (18)
- Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics. (2016) (18)
- Palbociclib demonstrates intracranial activity in progressive brain metastases harboring cyclin-dependent kinase pathway alterations (2021) (18)
- Alliance A071401: Phase II trial of FAK inhibition in meningiomas with somatic NF2 mutations. (2020) (17)
- Recombinase activating gene enzymes of lymphocytes (2001) (17)
- Fatal Eastern Equine Encephalitis in a Patient on Maintenance Rituximab: A Case Report (2017) (15)
- Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022. (2020) (15)
- Temporal and spatial topography of cell proliferation in cancer (2021) (14)
- Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-In-Class Antibody-Drug Conjugate. (2021) (14)
- Novel MPZ mutations and congenital hypomyelinating neuropathy (2010) (13)
- UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues (2021) (13)
- Mechanism of JCV Entry into Oligodendrocytes (2005) (13)
- Distinct patterns of primary and motile cilia in Rathke’s cleft cysts and craniopharyngioma subtypes (2016) (13)
- Alliance A071601: Phase II trial of BRAF/MEK inhibition in newly diagnosed papillary craniopharyngiomas. (2021) (12)
- Minerva: a light-weight, narrative image browser for multiplexed tissue images (2020) (12)
- Online narrative guides for illuminating tissue atlas data and digital pathology images (2020) (11)
- The RAG 1 Homeodomain Recruits HMG 1 and HMG 2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG 1-RAG 2 (1999) (11)
- A human breast atlas integrating single-cell proteomics and transcriptomics. (2022) (11)
- Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer (2021) (11)
- Telomere length alterations and ATRX/DAXX loss in pituitary adenomas (2020) (10)
- Erratum: Genomic landscape of high-grade meningiomas (2017) (10)
- Interpretative guides for interacting with tissue atlas and digital pathology data using the Minerva browser (2020) (10)
- Spatial genomics maps the structure, nature and evolution of cancer clones (2022) (10)
- HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor (2021) (9)
- Case-Based Review: meningioma. (2016) (9)
- Implication of Tubby Proteins as Transcription Factors by Structure-Based Functional Analysis (2000) (9)
- Nuclear CRX and FOXJ1 Expression Differentiates Non–Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region (2017) (8)
- Sporadic multiple meningiomas harbor distinct driver mutations (2021) (8)
- Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data (2021) (8)
- Intramedullary neuroma of the cervicomedullary junction. Case report. (2006) (8)
- New molecular targets in meningiomas: the present and the future (2018) (8)
- HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state (2022) (8)
- Meningioma transcription factors link cell lineage with systemic metabolic cues (2018) (7)
- Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma (2022) (7)
- Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making. (2021) (6)
- Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations (2022) (6)
- V(D)J recombination defects in lymphocytes: a severe immunodeficiency with a spectrum of clinical presentations due to Rag mutations (2000) (6)
- Society for Melanoma Research 2015 Congress (2015) (6)
- Santagata Supports the Anabolic Malignant State Tight Coordination of Protein Translation and HSF 1 Activation (2014) (5)
- Epidermal growth factor receptor gene amplification in atypical adenomatous hyperplasia of the lung. (2010) (5)
- Anaplastic variant of medulloblastoma mimicking a vestibular schwannoma (2006) (5)
- Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer (2020) (5)
- SU-D-207B-02: Early Grade Classification in Meningioma Patients Combining Radiomics and Semantics Data. (2016) (5)
- 2905 Genomic characterization of brain metastases and paired primary tumors reveals branched evolution and potential therapeutic targets (2015) (5)
- SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma (2020) (5)
- Abstract 5181: Therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumor (GIST), with DS-6157a, an antibody-drug conjugate (ADC) (2020) (5)
- Mycosis fungoides with leptomeningeal involvement. (2007) (4)
- Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery (2021) (4)
- Micro-region transcriptomics of fixed human tissue using Pick-Seq (2021) (4)
- Rapid Mass Spectrometry Imaging to Assess the Biochemical Profile of Pituitary Tissue for Potential Intraoperative Usage. (2017) (4)
- Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress (2019) (4)
- Radiographic Prediction of Meningioma Grade and Genomic Profile (2017) (4)
- Correction to: An update on the CNS manifestations of neurofibromatosis type 2 (2019) (4)
- Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features. (2022) (4)
- Multiplexed proteomics and imaging of resolving and lethal SARS-CoV-2 infection in the lung (2020) (3)
- Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data (2021) (3)
- Spatial transcriptomics. (2022) (3)
- Susan Lindquist (1949–2016) (2016) (3)
- Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data (2022) (3)
- Multimodal platform for assessing drug distribution and response in clinical trials. (2021) (3)
- Transcriptomic and Genomic Analyses of Human Craniopharyngioma (2017) (3)
- Uncovering the links between systemic hormones and oncogenic signaling in the pathogenesis of meningioma. (2018) (3)
- BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS (2014) (2)
- Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma (2019) (2)
- Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section (2023) (2)
- BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS (2014) (2)
- Integrating Genomics Into Neuro-Oncology Clinical Trials and Practice. (2018) (2)
- CTNI-11. CC-115 IN NEWLY DIAGNOSED MGMT UNMETHYLATED GLIOBLASTOMA IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II RANDOMIZED BAYESIAN ADAPTIVE PLATFORM TRIAL (2020) (2)
- CRAN-11. MULTIPLEXED IMMUNOFLUORESCENCE REVEALS POTENTIAL PD-1/PD-L1 PATHWAY VULNERABILITIES IN CRANIOPHARYNGIOMA (2018) (2)
- Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer (2020) (2)
- Systemic Lymphoid Architecture Response Assessment (SYLARAS): An approach to multi-organ, discovery-based immunophenotyping implicates a role for CD45R/B220+ CD8T cells in glioblastoma immunology (2019) (2)
- CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION (2020) (2)
- Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging (2019) (2)
- DESI then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections (2011) (2)
- Abstract NG03: Genomic characterization of 101 brain metastases and paired primary tumors reveals patterns of clonal evolution and selection of driver mutations (2014) (2)
- Orbital leiomyosarcoma metastasis presenting prior to diagnosis of the primary tumor. (2017) (2)
- A Prognostic Molecular Scoring System to Guide the Adjuvant Management of Patients With Gross Totally Resected Atypical Meningioma (2015) (1)
- GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS (2017) (1)
- CTNI-05. PRELIMINARY RESULTS OF THE NERATINIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION (2021) (1)
- RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA (2018) (1)
- GE-05EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS. (2014) (1)
- 53. Genomic characterization of brain metastases identifies drivers of metastatic lung adenocarcinoma (2020) (1)
- GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS (2017) (1)
- Mechanisms and therapeutic implications of hypermutation in gliomas (2020) (1)
- Molecular characterization and management of secondary resistance to serial TRK inhibitors. (2019) (1)
- DIPG-44. H3K27-altered diffuse midline gliomas with secondary driver molecular alterations (2022) (1)
- Post-irradiation meningioma with sarcoidosis (2007) (1)
- OS9.1 Clinical significance of hypermutation in gliomas (2019) (1)
- Abstract PS18-02: Highly multiplexed tissue-based cyclic immunofluorescence (t-CyCIF) for precision oncology identifies novel patterns of HER2 heterogeneity in breast cancer (2021) (1)
- Basal NK activity and early Treg function inhibition predicts Nivolumab responsiveness in metastatic renal cancer patients (REVOLUTION) trial (2019) (1)
- Abstract 482: Rapid highly multiplexed immunoprofiling of human fixed tissues by Orion imaging (2021) (1)
- Prognostication for meningiomas: H3K27me3 to the rescue? (2021) (1)
- Combined whole genome copy number genotyping and multiplex somatic mutation profiling of FFPE brain tumor specimens for clinical diagnosis and trial selection. (2013) (1)
- The impact of puberty on tumor incidence & progression in childhood low grade glioma (2014) (1)
- Relapsing Tumefactive Lesion in an Adult with Medulloblastoma Previously Treated with Chemoradiotherapy and Stem Cell Transplant (2012) (1)
- Label-free biomolecular characterization of human breast cancer tissue with stimulated Raman scattering (SRS) spectral imaging (Conference Presentation) (2017) (1)
- PD-L1 and PD-1 expression in pediatric central nervous system germ cell tumors (2022) (1)
- Author response: Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes (2018) (1)
- OS06.4 Identification of novel NTRK fusion in glioneuronal tumors and radiographic response following therapy with an NTRK inhibitor (2017) (1)
- Mutations are Common in Pleomorphic Xanthoastrocytoma : Diagnostic and Therapeutic Implications (2011) (1)
- OS08.3 Genomic landscape of meningiomas (2017) (1)
- A case of molecularly profiled extraneural medulloblastoma metastases in a child (2018) (1)
- Molecular and Clinical Characterization of Radiation-Induced Meningiomas (2022) (0)
- PATH-34. SOLITARY FIBROUS TUMOR: NATURAL HISTORY AND PROGNOSIS IN ACCORDANCE WITH THE WHO 2021 CLASSIFICATION OF CNS TUMORS (2022) (0)
- Atypical Histopathological Features and the Risk of Progression/Recurrence in WHO Grade I-II Meningiomas (2018) (0)
- C-Terminal Domain Of Mouse Brain Tubby Protein bound to Phosphatidylinositol 4,5-bis-phosphate (2001) (0)
- Abstract OT3-2-05: Randomized phase II study of fulvestrant with or without ganetespib in patients (pts) with hormone receptor (HR)-positive metastatic breast cancer (2013) (0)
- Systemic immune response profiling with SYLARAS implicates a role for CD45R/B220+ CD8+ T cells in glioblastoma immunology (2019) (0)
- RARE-07. THE LANDSCAPE OF GENOMIC ALTERATIONS IN ADAMANTINOMATOUS CRANIOPHARYNGIOMAS (2020) (0)
- The V(D)J recombination reaction: role of RAG1 and RAG2 In lymphocytes, the RAG1/RAG2 recombinase directs nucleolytic cleavage events through the recognition and synapsis of a pair of recombination signal sequences (0)
- Inhibition of mitochondrial ferredoxin 1 (FDX1) prevents adaptation to proteotoxic stress (2018) (0)
- Novel Oncogenic SMO and AKT1 Mutations in Meningiomas (2013) (0)
- ALLELE: A consortium for prospective genomics and functional diagnostics to guide patient care and trial analysis in newly-diagnosed glioblastoma. (2018) (0)
- Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma (2022) (0)
- Sporadic multiple meningiomas harbor distinct driver mutations (2021) (0)
- Tight Coordination of Protein Translation and Heat Shock Factor 1 Activation Supports the Anabolic Malignant State (2013) (0)
- Integrative whole-genome copy number analysis and mutation profiling of FFPE brain tumor specimens and potential in designing multi-arm clinical trials. (2014) (0)
- FFPE Tissue Pre-treatment Before t-CyCIF on Leica Bond RX v2 (2019) (0)
- Translational Breast Cancer Research Consortium 022: Pre- and Post-operative Neratinib for HER2-positive Breast Cancer Brain Metastases (2020) (0)
- Abstract P5-04-01: PARP inhibition modulates the infiltration, phenotype and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the anti-tumor potential of TAMs (2020) (0)
- Abstract 803: Genomic sequencing of meningiomas reveals oncogenic SMO and AKT1 mutations. (2013) (0)
- Within the Recombination-Activating Genes Definition of Minimal Domains of Interaction (2013) (0)
- GENO-09LANDSCAPE OF GENOMIC ALTERATIONS IN PITUITARY ADENOMAS (2015) (0)
- PATH-35. A SCALABLE MOLECULARLY INTEGRATED CLASSIFIER FOR MENINGIOMA OUTPERFORMS WHO CLASSIFICATION (2020) (0)
- Abstract P010: Antigen dominance hierarchies shape CD8 T cell phenotypes and immunotherapy response in tumors (2022) (0)
- PATH-17. DISTINCT MOLECULAR SUBCLASSES OF H3F3A-WILDTYPE, EGFR-ALTERED PEDIATRIC-TYPE DIFFUSE MIDLINE GLIOMAS WHO CNS GRADE 4 (2022) (0)
- Molecular and Cellular Pathobiology Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry (2012) (0)
- Genetic Alterations in Skull Base Meningiomas (2015) (0)
- BMET-04LEPTOMENINGEAL CARCINOMATOSIS IN MELANOMA (2015) (0)
- ING Rapid , Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy (2013) (0)
- RARE-04. TARGETED TREATMENT OF PAPILLARY CRANIOPHARYNGIOMAS HARBORING BRAFV600E MUTATIONS (2019) (0)
- PATH-16. MOLECULAR PATHOLOGY AND CLINICAL CHARACTERISTICS OF MMR DEFICIENCY (MMRd) IN DIFFUSE GLIOMAS (2018) (0)
- Minbiao Ji Scattering Microscopy Rapid , Label-Free Detection of Brain Tumors with Stimulated Raman (2013) (0)
- INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA (2018) (0)
- PATH-30. GENOMIC LANDSCAPE OF CENTRAL NERVOUS SYSTEM TUMORS (2017) (0)
- Abstract A23: Cell autonomous and nonautonomous activities of heat shock factor 1 support tumor initiation, progression, and metastasis (2013) (0)
- Abstract AP22: DNA DAMAGE RESPONSES AND IMMUNE PROFILING THROUGH HIGHLY MULTIPLEXED TISSUE IMMUNOFLUORESCENCE (T-CYCIF) IN HIGH-GRADE SEROUS OVARIAN CANCER (2019) (0)
- CMET-33. PHASE II STUDY OF PALBOCICLIB IN BRAIN METASTASES HARBORING CDK PATHWAY ALTERATIONS (2019) (0)
- Elevated Expression of Programmed Death Ligand1 in Human Pituitary Tumors (2016) (0)
- A Young Woman With Seizures: A Case of Neuroschistosomiasis (P2.321) (2014) (0)
- Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer (2023) (0)
- Sporadic hemangioblastomas are characterized by cryptic VHL inactivation (2014) (0)
- HSF1 phase transition mediates stress adaptation and cell fate decisions (2020) (0)
- LG-001. OPTIC PATHWAY GLIOMAS; FROM CHILDHOOD TO ADULTHOOD (2014) (0)
- Craniopharyngioma Pathogenesis and Implications for Medical Management (2017) (0)
- Abstract A9: Systemic immune response profiling with SYLARAS implicates a role for CD45R/B220+ CD8+ T cells in glioblastoma immunology (2020) (0)
- Abstract P5-02-03: Highly multiplexed tissue-based cyclic immunofluorescence in breast cancer for precision oncology (2020) (0)
- CTNI-53. RADIATION TREATMENT VOLUMES BEFORE AND AFTER BRAF/MEK THERAPY IN NEWLY DIAGNOSED PAPILLARY CRANIOPHARYNGIOMAS: A CORRELATIVE ANALYSIS OF THE ALLIANCE A071601 PHASE II TRIAL (2021) (0)
- P04.09 Frequent inactivating mutations of PBRM1 in meningioma with papillary features (2021) (0)
- Identification of clinically actionable PI3K pathway mutations in brain metastases from breast cancer (S41.006) (2017) (0)
- Abstract A028: Multi-modal digital pathology by sequential acquisition and joint analysis of highly multiplexed immunofluorescence and hematoxylin and eosin images (2022) (0)
- 18. ALLELE: A consortium for prospective genomics and functional diagnostics to guide patient care and trial analysis in newly-diagnosed glioblastoma (2018) (0)
- Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling (2017) (0)
- Molecular Taxonomy of Meningioma (2020) (0)
- Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma (2020) (0)
- 46. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES (2020) (0)
- Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses (2021) (0)
- Abstract P2-07-13: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer (2022) (0)
- Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
- Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
- USCAP 2018 Abstracts: Breast Pathology (121–337) (2018) (0)
- Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery (2021) (0)
- MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY (2015) (0)
- MEDU-37. NEURONAL DIFFERENTIATION AND CELL-CYCLE PROGRAMS MEDIATE RESPONSE AND RESISTANCE TO BET-BROMODOMAIN INHIBITION IN MYC-DRIVEN MEDULLOBLASTOMA (2019) (0)
- Tumors of the Central Nervous System (2018) (0)
- Integrative Copy Number and Mutational Analysis Improves Glioma Diagnostics (2014) (0)
- P5-01-13: High Levels of Nuclear Heat Shock Factor 1 (HSF1) Are Associated with Poor Prognosis in Breast Cancer: Results from the Nurses' Health Study. (2011) (0)
- Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer (2020) (0)
- Eastern Equine Encephalitis in a Patient Treated with Rituximab: Clinical Presentation and Histopathology (P4.316) (2014) (0)
- USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities (2023) (0)
- TMOD-03. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES (2020) (0)
- Abstract B067: Taxonomy of breast cancer based on normal cell phenotype and ontology (2013) (0)
- Abstract 4487: Association of the tumor-immune microenvironment with response to niraparib and pembrolizumab in relapsed, platinum-resistant ovarian cancer (2019) (0)
- Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations (2015) (0)
- Skull Base Tumors: Neuropathology and Clinical implications. (2021) (0)
- DRES-08. CLINICAL SIGNIFICANCE OF HYPERMUTATION IN GLIOMAS (2019) (0)
- Supports the Anabolic Malignant State Tight Coordination of Protein Translation and HSF1 Activation (2014) (0)
- PATH-03. CLINICAL UTILITY OF NEXT GENERATION SEQUENCING IN IDH-WILDTYPE GLIOBLASTOMA: THE DANA-FARBER CANCER INSTITUTE EXPERIENCE (2020) (0)
- Genomic Landscape of Pituitary Adenomas (2016) (0)
- Abstract LB056: The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution (2022) (0)
- P04.04.A A comprehensive genomic study of 390 H3F3A-mutant pediatric-type diffuse high-grade gliomas WHO CNS grade 4 (2022) (0)
- 3D multiplexed tissue imaging reconstruction and optimized region-of-interest (ROI) selection through deep learning model of channels embedding (2022) (0)
- TAMI-45. PHENOGENOMIC CHARACTERIZATION OF IMMUNOMODULATORY PURINERGIC SIGNALING IN GLIOBLASTOMA (2020) (0)
- P3-01-09: Oncogenic Activation of HSF1 Enables the Malignant Progression of Breast Carcinoma. (2011) (0)
- Abstract 122: Highly multiplexed, spatially-resolved tissue imaging of genetically engineered mouse models of cancer to discover and characterize immune regulators of tumorigenesis (2021) (0)
- Erratum: Genomic landscape of high-grade meningiomas (2017) (0)
- Abstract A28: Targeting the epigenetic state regulating cancer cell vulnerability to proteasome inhibition (2017) (0)
- GENE-63. GENOMIC CHARACTERIZATION OF HUMAN BRAIN METASTASES IDENTIFIES NOVEL DRIVERS OF LUNG ADENOCARCINOMA PROGRESSION (2019) (0)
- 860 Targeting immunosuppressive macrophages overcomes PARP-inhibitor resistance in BRCA1-associated triple-negative breast cancer (2020) (0)
- Abstract 1816: Phenogenomic characterization of immunomodulatory purinergic signaling in glioblastoma (2021) (0)
- Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic (2020) (0)
- Abstract 4729: Identifying genomic drivers of lung adenocarcinoma brain metastases (2020) (0)
- Abstract 139: DNA damage and immunoprofiling with highly multiplexed tissue immunofluorescence (t-CycIF) in high-grade serous ovarian cancer (2018) (0)
- Tissue Cyclic Immunofluorescence (t-CyCIF) v2 (2020) (0)
- Abstract A105: PARP inhibition modulates the infiltration, phenotype, and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the antitumor potential of TAMs (2020) (0)
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