Santiago F. Elena
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Biology
Santiago F. Elena's Degrees
- PhD Molecular Biology University of Barcelona
- Bachelors Biology University of Barcelona
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(Suggest an Edit or Addition)Santiago F. Elena's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation (2003) (1288)
- PERSPECTIVE:EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS (2003) (637)
- The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus. (2004) (563)
- Basic concepts in RNA virus evolution (1996) (443)
- Test of synergistic interactions among deleterious mutations in bacteria (1997) (411)
- Punctuated Evolution Caused by Selection of Rare Beneficial Mutations (1996) (304)
- Adaptive Value of High Mutation Rates of RNA Viruses: Separating Causes from Consequences (2005) (278)
- Clonal interference and the evolution of RNA viruses. (1999) (272)
- The evolution of sex: empirical insights into the roles of epistasis and drift (2007) (270)
- Endosymbiotic bacteria: GroEL buffers against deleterious mutations (2002) (261)
- Exponential increases of RNA virus fitness during large population transmissions. (1995) (246)
- The contribution of epistasis to the architecture of fitness in an RNA virus. (2004) (238)
- Cost of host radiation in an RNA virus. (2000) (215)
- Extremely High Mutation Rate of a Hammerhead Viroid (2009) (208)
- Distribution of Fitness and Virulence Effects Caused by Single-Nucleotide Substitutions in Tobacco Etch Virus (2007) (195)
- RNA virus quasispecies: significance for viral disease and epidemiology. (1994) (193)
- Distributions of epistasis in microbes fit predictions from a fitness landscape model (2007) (192)
- The causes of epistasis (2011) (179)
- The Fittest versus the Flattest: Experimental Confirmation of the Quasispecies Effect with Subviral Pathogens (2006) (174)
- Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses (1993) (174)
- Epistasis correlates to genomic complexity (2006) (170)
- The red queen reigns in the kingdom of RNA viruses. (1994) (165)
- The evolution of RNA viruses: A population genetics view. (2000) (162)
- Mechanisms of genetic robustness in RNA viruses (2006) (154)
- Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness (1995) (151)
- Distribution of fitness effects caused by random insertion mutations in Escherichia coli (2004) (138)
- Viroids: survivors from the RNA world? (2014) (134)
- Subclonal components of consensus fitness in an RNA virus clone (1994) (132)
- Evolution and emergence of plant viruses. (2014) (132)
- Natural Selection Fails to Optimize Mutation Rates for Long-Term Adaptation on Rugged Fitness Landscapes (2008) (128)
- EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS (2003) (123)
- Virus Evolution: Insights from an Experimental Approach (2007) (120)
- Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells (1995) (110)
- Matters of Size: Genetic Bottlenecks in Virus Infection and Their Potential Impact on Evolution. (2015) (108)
- Multihost experimental evolution of a plant RNA virus reveals local adaptation and host-specific mutations. (2012) (107)
- The evolutionary genetics of emerging plant RNA viruses. (2011) (106)
- Viroids: an Ariadne's thread into the RNA labyrinth (2006) (105)
- Evolution and ecology of plant viruses (2019) (104)
- Effect of Host Species on the Distribution of Mutational Fitness Effects for an RNA Virus (2011) (103)
- Phylogeny of viroids, viroidlike satellite RNAs, and the viroidlike domain of hepatitis delta virus RNA. (1991) (102)
- The Evolution of Viruses in Multi-Host Fitness Landscapes (2009) (97)
- Molecular basis of adaptive convergence in experimental populations of RNA viruses. (2002) (97)
- Molecular Evolution of a Viral Non-Coding Sequence under the Selective Pressure of amiRNA-Mediated Silencing (2009) (96)
- Epistasis and the Adaptability of an RNA Virus (2005) (93)
- Mixed Infections of Pepino Mosaic Virus Strains Modulate the Evolutionary Dynamics of this Emergent Virus (2009) (92)
- One Is Enough: In Vivo Effective Population Size Is Dose-Dependent for a Plant RNA Virus (2011) (91)
- Contribution of recombination and selection to molecular evolution of Citrus tristeza virus. (2009) (88)
- The Rate and Spectrum of Spontaneous Mutations in a Plant RNA Virus (2010) (88)
- Virus Adaptation by Manipulation of Host's Gene Expression (2008) (85)
- Diminishing Returns of Population Size in the Rate of RNA Virus Adaptation (2000) (82)
- Advances in plant virus evolution: translating evolutionary insights into better disease management. (2011) (82)
- A Sliding Window-Based Method to Detect Selective Constraints in Protein-Coding Genes and Its Application to RNA Viruses (2002) (82)
- Fitness Declines in Tobacco Etch Virus upon Serial Bottleneck Transfers (2007) (80)
- Reverse-engineering the Arabidopsis thaliana transcriptional network under changing environmental conditions (2009) (79)
- A real-time RT-PCR assay for quantifying the fitness of tobacco etch virus in competition experiments. (2007) (78)
- Corrigendum: Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations (2015) (75)
- Experimental evolution of plant RNA viruses (2008) (75)
- The pleiotropic cost of host-specialization in Tobacco etch potyvirus. (2008) (74)
- From Hypo- to Hypersuppression: Effect of Amino Acid Substitutions on the RNA-Silencing Suppressor Activity of the Tobacco etch potyvirus HC-Pro (2008) (73)
- EFFECTS OF POPULATION SIZE AND MUTATION RATE ON THE EVOLUTION OF MUTATIONAL ROBUSTNESS (2007) (71)
- A Meta-Analysis Reveals the Commonalities and Differences in Arabidopsis thaliana Response to Different Viral Pathogens (2012) (70)
- Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus (2012) (70)
- Measuring Selection Coefficients Below 10−3: Method, Questions, and Prospects (2012) (69)
- Little Evidence for Synergism Among Deleterious Mutations in a Nonsegmented RNA Virus (1999) (69)
- LONG‐TERM EXPERIMENTAL EVOLUTION IN ESCHERICHIA COLI. VII. MECHANISMS MAINTAINING GENETIC VARIABILITY WITHIN POPULATIONS (1997) (68)
- Analysis of epistatic interactions and fitness landscapes using a new geometric approach (2007) (66)
- Many-trillionfold amplification of single RNA virus particles fails to overcome the Muller's ratchet effect (1993) (65)
- Simple genomes, complex interactions: epistasis in RNA virus. (2010) (64)
- EPISTASIS BETWEEN NEW MUTATIONS AND GENETIC BACKGROUND AND A TEST OF GENETIC CANALIZATION (2001) (64)
- Application of game theory to the interaction between plant viruses during mixed infections. (2009) (62)
- Changes in the gene expression profile of Arabidopsis thaliana after infection with Tobacco etch virus (2008) (61)
- Insights into the Selective Pressures Restricting Pelargonium Flower Break Virus Genome Variability: Evidence for Host Adaptation (2006) (60)
- The effect of genetic robustness on evolvability in digital organisms (2008) (60)
- Towards an integrated molecular model of plant-virus interactions. (2012) (60)
- Epistasis between mutations is host-dependent for an RNA virus (2013) (59)
- Phylogeography and Molecular Evolution of Potato virus Y (2012) (57)
- Tempo and Mode of Plant RNA Virus Escape from RNA Interference-Mediated Resistance (2011) (55)
- Interaction network of tobacco etch potyvirus NIa protein with the host proteome during infection (2016) (54)
- Replication Mode and Landscape Topology Differentially Affect RNA Virus Mutational Load and Robustness (2009) (53)
- Editorial: A home for virology, ecology, epidemiology, and evolutionary biology (2015) (53)
- Within-Host Spatiotemporal Dynamics of Plant Virus Infection at the Cellular Level (2014) (52)
- Evolution of plant virus movement proteins from the 30K superfamily and of their homologs integrated in plant genomes. (2015) (52)
- Parasites and mutational load: an experimental test of a pluralistic theory for the evolution of sex (2005) (52)
- EVOLUTIONARY DYNAMICS OF FITNESS RECOVERY FROM THE DEBILITATING EFFECTS OF MULLER'S RATCHET (1998) (52)
- Evolution of fitness in experimental populations of vesicular stomatitis virus. (1996) (52)
- Dynamics of a Plant RNA Virus Intracellular Accumulation: Stamping Machine vs. Geometric Replication (2011) (52)
- Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV (2011) (52)
- The promiscuous evolutionary history of the family Bromoviridae. (2008) (50)
- Evolution of RNA virus in spatially structured heterogeneous environments (2003) (50)
- Transmission bottlenecks and the evolution of fitness in rapidly evolving RNA viruses. (2001) (48)
- Upper-limit mutation rate estimation for a plant RNA virus (2009) (46)
- The strands of both polarities of a small circular RNA from carnation self-cleave in vitro through alternative double- and single-hammerhead structures. (1992) (46)
- High genetic stability in natural populations of the plant RNA virus tobacco mild green mosaic virus (1991) (45)
- In silico predicted robustness of viroids RNA secondary structures. I. The effect of single mutations. (2006) (45)
- EXPERIMENTAL EVOLUTION OF AN EMERGING PLANT VIRUS IN HOST GENOTYPES THAT DIFFER IN THEIR SUSCEPTIBILITY TO INFECTION (2014) (45)
- Phylogenetic Analysis of Viroid and Viroid-Like Satellite RNAs from Plants: A Reassessment (2001) (45)
- A Viral Protein Mediates Superinfection Exclusion at the Whole-Organism Level but Is Not Required for Exclusion at the Cellular Level (2014) (44)
- Experimental Evolution of Pseudogenization and Gene Loss in a Plant RNA Virus (2013) (44)
- Simple quasispecies models for the survival-of-the-flattest effect: The role of space. (2008) (43)
- Emerging viruses: why they are not jacks of all trades? (2015) (43)
- The Two Faces of Mutation: Extinction and Adaptation in RNA Viruses (2000) (43)
- Virus Satellites Drive Viral Evolution and Ecology (2015) (42)
- Genomic divergence of Escherichia coli strains: evidence for horizontal transfer and variation in mutation rates. (2005) (42)
- Pear blister canker viroid is a member of the apple scar skin subgroup (apscaviroids) and also has sequence homology with viroids from other subgroups. (1992) (41)
- Ultradeep Sequencing Analysis of Population Dynamics of Virus Escape Mutants in RNAi-Mediated Resistant Plants (2012) (41)
- The games plant viruses play. (2014) (39)
- Estimation of the in vivo recombination rate for a plant RNA virus. (2014) (39)
- RNA virus genetic robustness: possible causes and some consequences. (2012) (39)
- Climb Every Mountain? (2003) (39)
- EFFECT OF DELETERIOUS MUTATION-ACCUMULATION ON THE FITNESS OF RNA BACTERIOPHAGE MS2 (2000) (37)
- Plant virus evolution under strong drought conditions results in a transition from parasitism to mutualism (2020) (36)
- FREQUENCY‐DEPENDENT SELECTION IN A MAMMALIAN RNA VIRUS (1997) (36)
- The utility of fitness landscapes and big data for predicting evolution (2018) (35)
- In silico predicted robustness of viroid RNA secondary structures. II. Interaction between mutation pairs. (2006) (35)
- Environmental stress and the effects of mutation (2003) (35)
- Coinfection and superinfection in RNA virus populations: a selection-mutation model. (2003) (34)
- EFFECT OF DELETERIOUS MUTATION‐ACCUMULATION ON THE FITNESS OF RNA BACTERIOPHAGE MS2 (2000) (34)
- From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics. (2020) (34)
- Effect of population patchiness and migration rates on the adaptation and divergence of vesicular stomatitis virus quasispecies populations. (1999) (34)
- A systems biology approach to the evolution of plant-virus interactions. (2011) (33)
- Genetic diversity of the movement and coat protein genes of South American isolates of Prunus necrotic ringspot virus (2008) (33)
- Quasispecies Spatial Models for RNA Viruses with Different Replication Modes and Infection Strategies (2011) (32)
- Within-host Evolution of Segments Ratio for the Tripartite Genome of Alfalfa Mosaic Virus (2016) (32)
- Effect of citrus hosts on the generation, maintenance and evolutionary fate of genetic variability of citrus exocortis viroid. (2009) (32)
- Large-population passages of vesicular stomatitis virus in interferon-treated cells select variants of only limited resistance (1996) (32)
- Error threshold in RNA quasispecies models with complementation. (2010) (31)
- Compensatory molecular evolution of HC-Pro, an RNA-silencing suppressor from a plant RNA virus. (2010) (30)
- Emergence and Phylodynamics of Citrus tristeza virus in Sicily, Italy (2013) (30)
- Temporal dynamics of intrahost molecular evolution for a plant RNA virus. (2015) (30)
- Adaptation of tobacco etch potyvirus to a susceptible ecotype of Arabidopsis thaliana capacitates it for systemic infection of resistant ecotypes (2010) (30)
- Exon/intron structure of the human alpha 3(IV) gene encompassing the Goodpasture antigen (alpha 3(IV)NC1). Identification of a potentially antigenic region at the triple helix/NC1 domain junction. (1992) (30)
- Shrinkage of Genome Size in a Plant RNA Virus upon Transfer of an Essential Viral Gene into the Host Genome (2014) (29)
- NATURAL SELECTION AND THE ORGAN‐SPECIFIC DIFFERENTIATION OF HIV‐1 V3 HYPERVARIABLE REGION (2004) (29)
- Topology analysis and visualization of Potyvirus protein-protein interaction network (2014) (29)
- Changes in the composition of the RNA virome mark evolutionary transitions in green plants (2016) (29)
- Multiple infection dynamics has pronounced effects on the fitness of RNA viruses (2001) (29)
- Viral Strain-Specific Differential Alterations in Arabidopsis Developmental Patterns. (2015) (28)
- Phylogeography and Molecular Evolution of Potato virus (2012) (27)
- Improving the Effectiveness of Artificial MicroRNA (amiR)-Mediated Resistance against Turnip Mosaic Virus by Combining Two amiRs or by Targeting Highly Conserved Viral Genomic Regions (2013) (27)
- Genetic diversity and potential vectors and reservoirs of Cucurbit aphid-borne yellows virus in southeastern Spain. (2013) (27)
- Molecular evolution and phylogeography of potato virus Y based on the CP gene. (2012) (27)
- Optimal viral strategies for bypassing RNA silencing (2011) (26)
- Effects of Potyvirus Effective Population Size in Inoculated Leaves on Viral Accumulation and the Onset of Symptoms (2012) (26)
- Molecular Evolution of the Plant Virus Family Bromoviridae Based on RNA3-Encoded Proteins (2005) (26)
- Structural Discrimination of Robustness in Transcriptional Feedforward Loops for Pattern Formation (2011) (26)
- Local adaptation of plant viruses: lessons from experimental evolution (2017) (26)
- Restrictions to RNA virus adaptation: An experimental approach (2002) (25)
- Phylodynamics of Pepino mosaic virus in Spain (2012) (25)
- Genotypic but not phenotypic historical contingency revealed by viral experimental evolution (2013) (25)
- PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS (2003) (25)
- Evolutionary relationships among members of the Bromoviridae deduced from whole proteome analysis (2006) (25)
- Molecular Evolution of Viral Multifunctional Proteins: The Case of Potyvirus HC-Pro (2013) (24)
- Effects of the Number of Genome Segments on Primary and Systemic Infections with a Multipartite Plant RNA Virus (2013) (24)
- Intra-specific variability and biological relevance of P3N-PIPO protein length in potyviruses (2013) (24)
- Is group selection a factor modulating the virulence of RNA viruses? (1997) (24)
- Adaptive Covariation between the Coat and Movement Proteins of Prunus Necrotic Ringspot Virus (2006) (24)
- RNA viruses as complex adaptive systems. (2005) (23)
- The transcriptomics of an experimentally evolved plant-virus interaction (2016) (23)
- Evaluating the within-host fitness effects of mutations fixed during virus adaptation to different ecotypes of a new host (2015) (23)
- Evolutionary Constraints to Viroid Evolution (2009) (22)
- The impact of high‐order epistasis in the within‐host fitness of a positive‐sense plant RNA virus (2015) (22)
- Dynamics of alternative modes of RNA replication for positive-sense RNA viruses (2012) (22)
- Nonlinear trade-offs allow the cooperation game to evolve from Prisoner's Dilemma to Snowdrift (2017) (22)
- Transcript Profiling of Different Arabidopsis thaliana Ecotypes in Response to Tobacco etch potyvirus Infection (2012) (22)
- Fate of artificial microRNA-mediated resistance to plant viruses in mixed infections. (2013) (21)
- Onset of virus systemic infection in plants is determined by speed of cell-to-cell movement and number of primary infection foci (2014) (21)
- Dynamics of the Establishment of Systemic Potyvirus Infection: Independent yet Cumulative Action of Primary Infection Sites (2012) (21)
- Role of host genetic diversity for susceptibility-to-infection in the evolution of virulence of a plant virus (2019) (21)
- Predicting the Stability of Homologous Gene Duplications in a Plant RNA Virus (2016) (21)
- Efficient escape from local optima in a highly rugged fitness landscape by evolving RNA virus populations (2016) (20)
- Role of host genetic diversity for susceptibility-to-infection in the evolution of virulence of a plant virus† (2019) (19)
- Molecular and biological characterization of an isolate of Tomato mottle mosaic virus (ToMMV) infecting tomato and other experimental hosts in eastern Spain (2017) (19)
- THE CAUSES OF EPISTASIS IN GENETIC NETWORKS (2012) (19)
- Luria-Delbrück Estimation of Turnip Mosaic Virus Mutation Rate In Vivo (2012) (18)
- Differences in Accumulation and Virulence Determine the Outcome of Competition during Tobacco etch virus Coinfection (2011) (18)
- Evolutionary history conditions the timing of transmission in vesicular stomatitis virus. (2001) (18)
- Computational design of genomic transcriptional networks with adaptation to varying environments (2012) (17)
- Effect of Host Species on Topography of the Fitness Landscape for a Plant RNA Virus (2016) (17)
- Relocation of the NIb Gene in the Tobacco Etch Potyvirus Genome (2014) (17)
- Molecular evolution of Pepino mosaic virus during long-term passaging in different hosts and its impact on virus virulence (2015) (17)
- Distribution of mutational fitness effects and of epistasis in the 5’ untranslated region of a plant RNA virus (2015) (17)
- Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations (2014) (16)
- Time-Sampled Population Sequencing Reveals the Interplay of Selection and Genetic Drift in Experimental Evolution of Potato Virus Y (2017) (16)
- Model-Selection-Based Approach for Calculating Cellular Multiplicity of Infection during Virus Colonization of Multi-Cellular Hosts (2013) (16)
- Viral Fitness Determines the Magnitude of Transcriptomic and Epigenomic Reprogramming of Defense Responses in Plants. (2020) (16)
- Global-scale computational analysis of genomic sequences reveals the recombination pattern and coevolution dynamics of cereal-infecting geminiviruses (2015) (16)
- 2b or Not 2b: Experimental Evolution of Functional Exogenous Sequences in a Plant RNA Virus (2016) (15)
- Defective RNA particles derived from Tomato black ring virus genome interfere with the replication of parental virus. (2018) (15)
- From foes to friends: Viral infections expand the limits of host phenotypic plasticity. (2020) (15)
- Low genetic variability in the coat and movement proteins of American plum line pattern virus isolates from different geographic origins (2007) (14)
- Viruses as Complex Adaptive Systems (2018) (14)
- Viral Fitness Correlates with the Magnitude and Direction of the Perturbation Induced in the Host’s Transcriptome: The Tobacco Etch Potyvirus—Tobacco Case Study (2018) (14)
- Evolutionary transitions during RNA virus experimental evolution (2016) (14)
- Complex dynamics of defective interfering baculoviruses during serial passage in insect cells (2013) (14)
- Complete nucleotide sequence of a novel mycovirus from Trichoderma harzianum in China (2019) (14)
- Structure and Evolution of Viroids (2008) (14)
- Brazilian Potato virus Y isolates identified as members of a new clade facilitate the reconstruction of evolutionary traits within this species (2015) (13)
- Network design meets in silico evolutionary biology. (2010) (13)
- Virus-host interactome: Putting the accent on how it changes. (2017) (13)
- HC-Pro hypo- and hypersuppressor mutants: differences in viral siRNA accumulation in vivo and siRNA binding activity in vitro (2010) (13)
- Evolutionary Constraints on Emergence of Plant RNA Viruses (2010) (12)
- Plant RNA virus fitness predictability: contribution of genetic and environmental factors (2013) (12)
- The degree of plant resilience to infection correlates with virus virulence and host-range (2008) (11)
- Multiple Barriers to the Evolution of Alternative Gene Orders in a Positive-Strand RNA Virus (2016) (11)
- r- and K-selection in experimental populations of vesicular stomatitis virus. (2002) (11)
- Defects in plant immunity modulate the rates and patterns of RNA virus evolution (2020) (11)
- Experimental Virus Evolution Reveals a Role of Plant Microtubule Dynamics and TORTIFOLIA1/SPIRAL2 in RNA Trafficking (2014) (11)
- Increasing temperature alters the within-host competition of viral strains and influences virus genetic variability (2021) (10)
- Going, going, gone: predicting the fate of genomic insertions in plant RNA viruses (2018) (10)
- Adaptation of turnip mosaic potyvirus to a specific niche reduces its genetic and environmental robustness (2020) (10)
- Evolving by deleting: patterns of molecular evolution of Apple stem pitting virus isolates from Poland. (2019) (10)
- Parsimonious Scenario for the Emergence of Viroid-Like Replicons De Novo (2019) (10)
- Modeling multipartite virus evolution: the genome formula facilitates rapid adaptation to heterogeneous environments† (2020) (10)
- Transmission modes affect the population structure of potato virus Y in potato (2020) (10)
- Repeated transfer of small RNA virus populations leading to balanced fitness with infrequent stochastic drift (1996) (9)
- Assessing parallel gene histories in viral genomes (2016) (9)
- Viral fitness determines the magnitude of transcriptomic and epigenomic reprogramming of defense responses in plants (2019) (9)
- Mode of selection and experimental evolution of antiviral drugs resistance in vesicular stomatitis virus. (2005) (9)
- New experimental and theoretical approaches towards the understanding of the emergence of viral infections (2010) (9)
- The Interplay between the Host Microbiome and Pathogenic Viral Infections (2021) (8)
- A genome-wide association study identifies Arabidopsis thaliana genes that contribute to differences in the outcome of infection with two Turnip mosaic potyvirus strains that differ in their evolutionary history and degree of host specialization (2021) (8)
- Robust dynamical pattern formation from a multifunctional minimal genetic circuit (2010) (8)
- Spatially induced nestedness in a neutral model of phage-bacteria networks (2017) (8)
- Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis (2019) (8)
- Molecular and biological characterization of an isolate of Tomato mottle mosaic virus (ToMMV) infecting tomato and other experimental hosts in a greenhouse in Valencia, Spain (2016) (8)
- Does the VP1 gene of foot-and-mouth disease virus behave as a molecular clock? (1992) (7)
- Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein (2019) (7)
- Fine-Tuning Tomato Agronomic Properties by Computational Genome Redesign (2012) (7)
- Evolution. Climb every mountain? (2003) (7)
- A putative antiviral role of plant cytidine deaminases (2014) (7)
- Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes (2018) (6)
- Genetic variation in fitness within a clonal population of a plant RNA virus (2016) (6)
- Revisiting Orthotospovirus phylogeny using full-genome data and testing the contribution of selection, recombination and segment reassortment in the origin of members of new species (2021) (6)
- Intraclonal variation in RNA viruses: generation, maintenance and consequences (2003) (6)
- High virulence does not necessarily impede viral adaptation to a new host: a case study using a plant RNA virus (2016) (6)
- Population differentiation and selective constraints in Pelargonium line pattern virus. (2011) (6)
- Strain-dependent mutational effects for Pepino mosaic virus in a natural host (2017) (5)
- Identifying Early Warning Signals for the Sudden Transition from Mild to Severe Tobacco Etch Disease by Dynamical Network Biomarkers (2019) (5)
- Noise-induced bistability in the quasineutral coexistence of viral RNA under different replication modes (2018) (5)
- Molecular evolution of tomato black ring virus and de novo generation of a new type of defective RNAs during long‐term passaging in different hosts (2020) (5)
- Four principles to establish a universal virus taxonomy (2023) (5)
- NATURAL SELECTION AND THE ORGAN-SPECIFIC DIFFERENTIATION OF HIV-1 V3 HYPERVARIABLE REGION (2004) (5)
- Viral replication modes in single-peak fitness landscapes: A dynamical systems analysis. (2019) (5)
- An assessment of the transmission rate of Tomato black ring virus through tomato seeds (2019) (5)
- Phase transitions in virology (2020) (4)
- Computational design of host transcription-factors sets whose misregulation mimics the transcriptomic effect of viral infections (2012) (4)
- Evolvability drives innovation in viral genomes (2016) (4)
- Why are viral genomes so fragile? The bottleneck hypothesis (2021) (4)
- Transmission rate of two Polish Tomato torrado virus isolates through tomato seeds (2018) (4)
- Tridimensional model structure and patterns of molecular evolution of Pepino mosaic virus TGBp3 protein (2011) (4)
- DVGfinder: A Metasearch Tool for Identifying Defective Viral Genomes in RNA-Seq Data (2022) (4)
- Natural variation in Arabidopsis thaliana rosette area unveils new genes involved in plant development (2020) (4)
- The Core/E1 domain of hepatitis C virus genotype 4a in Egypt does not contain viral mutations or strains specific for hepatocellular carcinoma. (2011) (4)
- Exon/intron structure of the human alpha 3(IV) gene encompassing the Goodpasture antigen (alpha 3(IV)NC1). Identification of a potentially antigenic region at the triple helix/NC1 domain junction. (1994) (4)
- Innate immune pathways act synergistically to constrain RNA virus evolution in Drosophila melanogaster (2021) (3)
- Host developmental stages shape the evolution of a plant RNA virus (2023) (3)
- Characterization of the Arabidopsis thaliana Interactome Targeted by Viruses (2011) (3)
- Approximate variance of nucleotide divergence between two sequences estimated from restriction fragment data. (1995) (3)
- Fusion of genomic, proteomic and phenotypic data: the case of potyviruses. (2016) (3)
- Host-virus evolutionary dynamics with specialist and generalist infection strategies: Bifurcations, bistability, and chaos. (2019) (3)
- Virus Infection Suppresses Nicotiana benthamiana Adaptive Phenotypic Plasticity (2011) (3)
- DVGfinder: A Metasearch Engine for Identifying Defective Viral Genomes in RNA-Seq Data (2022) (2)
- A comprehensive physical interaction map between the Turnip mosaic potyvirus and Arabidopsis thaliana proteomes (2021) (2)
- Combined Stress Conditions in Melon Induce Non-additive Effects in the Core miRNA Regulatory Network (2021) (2)
- Exploring the role of cellular homologous of the 30K-superfamily of plant virus movement proteins. (2019) (2)
- LRH: JAGM DE VISSER, J HERMISSON ET AL. RRH: EVOLUTION OF ROBUSTNESS PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS (1972) (2)
- Host age-dependent evolution of a plant RNA virus (2022) (2)
- Evolution and ecology of plant viruses (2019) (2)
- Modelling temperature-dependent dynamics of single and mixed infections in a plant virus (2021) (2)
- Effect of defective interfering RNAs on the vertical transmission of Tomato black ring virus (2020) (2)
- MicroRNA Precursors Are Not Structurally Robust but Plastic (2012) (2)
- Exploring the role of cellular homologous of the 30K-superfamily of plant virus movement proteins (2018) (2)
- Effects of Potyvirus Effective Population 1 Size in Inoculated Leaves on Viral 2 Accumulation and the Onset of 3 Symptoms 4 (2012) (2)
- Testing the independent action hypothesis of plant pathogen mode of action: a simple and powerful new approach. (2015) (2)
- distributed major virus-resistance association in Arabidopsis thaliana (2022) (2)
- Genetic variability and evolutionary dynamics of tomato black ring virus population (2021) (2)
- Virus classification based on in-depth sequence analyses and development of demarcation criteria using the Betaflexiviridae as a case study. (2022) (1)
- Genotypic but not phenotypic historical contingency revealed by viral experimental evolution (2013) (1)
- Arabidopsis thaliana genes contributing to differences in the outcome of infection with generalist and specialist strains of Turnip mosaic virus identified by genome-wide association studies (2020) (1)
- EXPERIMENTAL EVOLUTION OF AN EMERGING PLANT (2014) (1)
- Dynamics of Potyvirus Systemic Infection Establishment : Independent yet Cumulative Action of Primary Infection Sites (2013) (1)
- RNAs That Behave Like Prions (2020) (1)
- 1 Tempo and Mode of Plant RNA Virus Escape from RNAi-Mediated Resistance (2012) (1)
- Differential effects of vertical and horizontal transmission in the fitness of an RNA virus: A reanalysis (2002) (1)
- Nestedness and modularity in plant-parasite infection networks (2021) (1)
- Viral fitness predicts the magnitude and direction of perturbations in the infected host transcriptome (2017) (1)
- Increasing growth temperature alters the within-host competition of viral strains and influences virus genetic variation (2020) (1)
- Going, going, gone: predicting the fate of genomic insertions in plant RNA viruses (2018) (1)
- Intra-specific variability and biological relevance of P3N-PIPO protein length in potyviruses (2013) (1)
- Evolved Modular Epistasis in Artificial Organisms (2012) (1)
- STABILITY OF A STOCHASTICALLY PERTURBED MODEL OF INTRACELLULAR SINGLE-STRANDED RNA VIRUS REPLICATION (2018) (1)
- Diminishing returns of inoculum size on the rate of a plant RNA virus evolution (2017) (1)
- COMPUTER VIRUSES AND BEYOND (2018) (0)
- Complete nucleotide sequence of a novel mycovirus from Trichoderma harzianum in China (2019) (0)
- Heterogeneity in the Response of Different Subtypes of Drosophila melanogaster Midgut Cells to Viral Infections (2021) (0)
- Environmental stress and mutational effects ( Minireview ) (2003) (0)
- Replication Mode and Landscape Topology 1 Affect Differentially RNA Virus Mutational 2 Load and Robustness (2009) (0)
- Population differentiation and selective constraints in Pelargonium line 2 pattern virus 3 4 (0)
- Within-host Evolution of Segments Ratio for the Tripartite Genome of Alfalfa Mosaic Virus (2017) (0)
- A binary interaction map between turnip mosaic virus and Arabidopsis thaliana proteomes (2023) (0)
- Heterogeneity in the response of different subtypes of Drosophila melanogaster enteroendocrine cells to viral infections (2020) (0)
- VIRUS DYNAMICS AND ARMS RACES (2018) (0)
- Alive or Dead? (2018) (0)
- The Virosphere (2018) (0)
- Supplementary material from "Noise-induced bistability in the quasi-neutral coexistence of viral RNAs under different replication modes. 21 February 2018 8 May 2018" (2018) (0)
- The long and winding road to understanding organismal construction: Reply to comments on "From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics". (2022) (0)
- Faculty Opinions recommendation of A virus responds instantly to the presence of the vector on the host and forms transmission morphs. (2013) (0)
- Genetic diversity and potential vectors and reservoirs of Cucurbit aphid-borne 1 yellows virus in southeastern Spain 2 3 (2014) (0)
- Revisiting Orthotospovirus phylogeny using full-genome data and testing the contribution of selection, recombination and segment reassortment in the origin of members of new species (2021) (0)
- Testing evolution predictability using the aevol software (2017) (0)
- Molecular and biological characterization of an isolate of Tomato mottle mosaic virus (ToMMV) infecting tomato and other experimental hosts in eastern Spain (2017) (0)
- 2 3 EXPERIMENTAL EVOLUTION OF AN EMERGING PLANT 4 VIRUS IN HOST GENOTYPES THAT DIFFER IN THEIR 5 SUSCEPTIBILITY TO INFECTION 6 7 (2016) (0)
- An Evolved 5′ Untranslated Region of Alfalfa Mosaic Virus Allows the RNA Transport of Movement-Defective Variants (2022) (0)
- No two without three: Modelling dynamics of the trio RNA virus-defective interfering genomes-RNA satellite (2023) (0)
- Evolving in drought conditions: consequences in the interaction between a potyvirus and Arabidopsis thaliana (2019) (0)
- Transmission rate of two Polish Tomato torrado virus isolates through tomato seeds (2018) (0)
- Engineered Genetic Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes (2018) (0)
- Experimental host-range expansion in a plant RNA virus: an interplay between viral fitness and regulation of host’s transcriptome (2018) (0)
- Epidemics (2018) (0)
- Differences among A. thaliana ecotypes in response to infection drives patterns of virus adaptation (2018) (0)
- Non-linear tradeoffs allow the cooperation game to evolve from Prisoner’s Dilemma to Snow Drift (2016) (0)
- Faculty Opinions recommendation of The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans. (2011) (0)
- Robustness to Mutations Depends on whether RNA Virus Replication Occurs Geometrically or Via a Stamping Machine (0)
- EvoEvo Deliverable 1.6 (2016) (0)
- Complex dynamics of defective interfering baculoviruses during serial passage in insect cells (2013) (0)
- Figure 3-Association of complexity with epistasis (2011) (0)
- Evaluation of Caenorhabditis elegans as experimental host for a thrip-transmitted plant RNA virus (2017) (0)
- 1 1 Luria-Delbrück Estimation of Turnip mosaic virus 2 Mutation Rate in vivo 3 4 (2012) (0)
- Defective RNA particles of Tomato black ring virus: origin, structure and biological effect (2018) (0)
- The contribution of plant RNA viruses to address fundamental questions in evolutionary biology (2018) (0)
- Tracking the Population Dynamics of Plant Virus Escape Mutants (2015) (0)
- Mechanisms of virus evolution and emergence (2018) (0)
- Application of Carleman approximants for the estimation of epidemic parameters from incidence data time-series (2022) (0)
- The tree of life: intertwining genomics and evolution (2020) (0)
- Faculty Opinions recommendation of RNA recombination enhances adaptability and is required for virus spread and virulence. (2016) (0)
- Faculty Opinions recommendation of Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis. (2012) (0)
- The utility of fitness landscapes and big data for predicting evolution (2018) (0)
- Contribution of recombination and selection to 1 molecular evolution of Citrus tristeza virus 2 3 (2009) (0)
- Assessing parallel gene histories in viral genomes (2016) (0)
- Faculty Opinions recommendation of Reciprocal gene loss following experimental whole-genome duplication causes reproductive isolation in yeast. (2011) (0)
- The promiscuous evolutionary history of the family (2008) (0)
- Distribution of mutational fitness effects and of epistasis in the 5’ untranslated region of a plant RNA virus (2015) (0)
- Spatially-induced nestedness in a neutral model of phage-bacteria networks (2017) (0)
- Molecular Evolution of Viral Multifunctional Proteins: The Case of Potyvirus HC-Pro (2013) (0)
- Interaction network of tobacco etch potyvirus NIa protein with the host proteome during infection (2016) (0)
- Single-cell RNA-sequencing data analysis reveals a highly correlated triphasic transcriptional response to SARS-CoV-2 infection (2022) (0)
- Faculty Opinions recommendation of The environment affects epistatic interactions to alter the topology of an empirical fitness landscape. (2013) (0)
- Plant Virus Adaptation to New Hosts: A Multi-scale Approach. (2023) (0)
- Strain-dependent mutational effects for Pepino mosaic virus in a natural host (2017) (0)
- Faculty Opinions recommendation of Beyond the consensus: dissecting within-host viral population diversity of foot-and-mouth disease virus by using next-generation genome sequencing. (2011) (0)
- Faculty Opinions recommendation of Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus. (2012) (0)
- Jump then Climb: can rearrangements predict the occurrence of mutational bursts? (2018) (0)
- The rugged adaptive landscape of an emerging plant RNA virus (2014) (0)
- Genetic diversity of Tomato black ring virus isolates collected from different hosts (2018) (0)
- Testofsynergisticinteractions amongdeleteriousmutations inbacteria (0)
- Exploring the miRNA-mediated response to combined stresses in melon plants (2021) (0)
- Latent Structures-based Modeling of Mutated Protein-Protein Interaction Networks (2014) (0)
- Genetic Diversity of Tomato Black Ring Virus Satellite RNAs and Their Impact on Virus Replication (2022) (0)
- Host variability in resistance genes conditions the evolution of emerging plant RNA viruses (2018) (0)
- Transmission of Diverse Variants of Strawberry Viruses Is Governed by a Vector Species (2022) (0)
- understanding of the emergence of viral infections New experimental and theoretical approaches towards the (2010) (0)
- High virulence does not necessarily impede viral adaptation to a new host: a case study using a plant RNA virus (2017) (0)
- Viral fitness correlates with the magnitude and direction of the perturbation induced in the host’s transcriptome (2017) (0)
- Emergent Viruses (2018) (0)
- Revisiting Orthotospovirus Phylogeny Using Whole Genomic Data and a Hypothesis for their Geographic Origin and Diversification (2020) (0)
- Dynamics of a plant RNA virus intracellular accumulation : stamping 1 machine versus geometric replication 2 3 4 (2011) (0)
- Effect of disease prevalence and growth stage on symptoms severity in the Turnip mosaic virus - Arabidopsis thaliana pathosystem (2023) (0)
- Etch Potyvirus Genome Relocation of the NIb Gene in the Tobacco (2014) (0)
- Origins (2018) (0)
- Phylodynamics of Pepino mosaic virus in Spain (2012) (0)
- EvoEvo Deliverable 6.8 (2014) (0)
- Viral replication modes in single-peak fitness landscapes: a dynamical systems analysis (2017) (0)
- Genetic basis of Arabidopsis thaliana responses to infection with naïve and adapted isolates of turnip mosaic virus (2023) (0)
- Changes in the composition of the RNA virome mark evolutionary transitions in green plants (2016) (0)
- Faculty Opinions recommendation of Environment determines epistatic patterns for a ssDNA virus. (2013) (0)
- Froissart understanding of the emergence of viral infections (2010) (0)
- Experimental plant virus evolution reveals a role of microtubule dynamics and TORTIFOLIA1/SPIRAL2 in RNA trafficking. (2014) (0)
- Genome-wide association studies of viral infections—A short guide to a successful experimental and statistical analysis (2022) (0)
- Froissart understanding of the emergence of viral infections (2010) (0)
- Improving the effectiveness of amiRNA-mediated resistance 3 against Turnip mosaic virus by combining two amiRNAs or by 4 targeting highly conserved viral genomic regions 5 6 (2014) (0)
- Level Is Not Required for Exclusion at the Cellular Exclusion at the Whole-Organism Level but A Viral Protein Mediates Superinfection (2014) (0)
- Evolving Living Technologies - Insights from the EvoEvo Project (2018) (0)
- In Vivo Virus Mutation Rate Luria-Delbrück Estimation of Turnip Mosaic (2012) (0)
- A putative antiviral role of plant cytidine deaminases. (2017) (0)
- Landscapes (2018) (0)
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What Schools Are Affiliated With Santiago F. Elena?
Santiago F. Elena is affiliated with the following schools: