Sara Sawyer
American cell biologist
Sara Sawyer's AcademicInfluence.com Rankings
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Biology
Sara Sawyer's Degrees
- Masters Biology Stanford University
- Bachelors Biology University of California, Berkeley
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Why Is Sara Sawyer Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Sara Lea Sawyer is a professor at the University of Colorado Boulder. She has received national and international prizes in virology. In 2011 she was as awarded the Presidential Early Career Award for Scientists and Engineers by President Barack Obama at the White House. She serves as a Senior Editor at the journal eLIFE, and as a government consultant on the topic of pandemic preparedness. In 2020, she co-founded Darwin Biosciences, an infectious disease diagnostics company located in Boulder, Colorado. In 2022, she was awarded the National Institutes of Health Director’s “Pioneer” award. Her research focuses on animal viruses that infect humans, including HIV-1, and the evolution of the immune system.
Sara Sawyer's Published Works
Published Works
- Possible emergence of new geminiviruses by frequent recombination. (1999) (1416)
- Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. (2005) (664)
- Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G (2004) (474)
- High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing (2013) (235)
- Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. (2000) (192)
- Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast (2015) (189)
- Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals (2007) (181)
- Two-stepping through time: mammals and viruses. (2011) (129)
- Dual Host-Virus Arms Races Shape an Essential Housekeeping Protein (2013) (121)
- Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication. (2018) (116)
- High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans (2006) (115)
- Molecular evolution of the antiretroviral TRIM5 gene (2009) (110)
- Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes (2011) (106)
- The Hexameric Eukaryotic MCM Helicase: Building Symmetry from Nonidentical Parts* (2000) (100)
- Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats (2015) (94)
- Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae. (2004) (91)
- Evidence for ACE2-Utilizing Coronaviruses (CoVs) Related to Severe Acute Respiratory Syndrome CoV in Bats (2012) (90)
- Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities (2021) (87)
- Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. (2017) (76)
- HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6 (2012) (75)
- Sequence analysis and classification of apparent recombinant begomoviruses infecting tomato in the nile and mediterranean basins. (2005) (72)
- Evolutionary Reconstructions of the Transferrin Receptor of Caniforms Supports Canine Parvovirus Being a Re-emerged and Not a Novel Pathogen in Dogs (2012) (70)
- Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors. (2013) (67)
- An expanded clade of rodent Trim5 genes. (2009) (67)
- Just 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in communities (2021) (64)
- Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis (2006) (57)
- How host genetics dictates successful viral zoonosis (2019) (54)
- Rapid evolution of BRCA1 and BRCA2 in humans and other primates (2014) (51)
- Positive selection of primate genes that promote HIV-1 replication. (2014) (44)
- Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir (2018) (44)
- A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species (2019) (41)
- Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins (2016) (39)
- A cross-species view on viruses. (2012) (37)
- An Evolutionary Screen Highlights Canonical and Noncanonical Candidate Antiviral Genes within the Primate TRIM Gene Family (2013) (36)
- TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation (2019) (35)
- XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts (2016) (34)
- An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. (2016) (34)
- Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins (2014) (32)
- Recent host-shifts in ranaviruses: signatures of positive selection in the viral genome. (2013) (31)
- The effect of species representation on the detection of positive selection in primate gene data sets. (2015) (31)
- Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers (2020) (30)
- Species-specific features of DARC, the primate receptor for Plasmodium vivax and Plasmodium knowlesi. (2012) (30)
- Ancient and Recent Adaptive Evolution of Primate Non-Homologous End Joining Genes (2010) (29)
- A community-deployable SARS-CoV-2 screening test using raw saliva with 45 minutes sample-to-results turnaround (2020) (21)
- Identification of Owl Monkey CD4 Receptors Broadly Compatible with Early-Stage HIV-1 Isolates (2015) (20)
- dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA (2019) (17)
- Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes (2018) (16)
- Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses (2015) (15)
- Control of yeast retrotransposons mediated through nucleoporin evolution (2018) (13)
- Molecular diversity of RNA-2 genome segments in pecluviruses causing peanut clump disease in West Africa and India (2003) (12)
- A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction (2016) (10)
- RNase L limits host and viral protein synthesis via inhibition of mRNA export (2021) (10)
- Analyzing machupo virus-receptor binding by molecular dynamics simulations (2013) (10)
- A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV) (2019) (10)
- Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae (2004) (9)
- Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism. (2016) (9)
- At the mercy of viruses (2016) (8)
- Selective use of primate CD4 receptors by HIV-1 (2019) (8)
- Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers (2021) (8)
- D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B. (2013) (7)
- Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry. (2017) (7)
- Monkeypox emergency: Urgent questions and perspectives (2022) (6)
- Positive natural selection in primate genes of the type I interferon response (2021) (6)
- Primate hemorrhagic fever-causing arteriviruses are poised for spillover to humans (2022) (6)
- Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. (2014) (6)
- Two-stage ML Classifier for Identifying Host Protein Targets of the Dengue Protease (2019) (4)
- RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus (2022) (4)
- 2019-0611 TRIM 5 alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation (2019) (3)
- Rapid evolution of BRCA1 and BRCA2in humans and other primates (2014) (2)
- D 316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC 3 B (2013) (2)
- RNase L-mediated RNA decay alters 3’ end formation and splicing of host mRNAs (2022) (1)
- Optimizing polymerase chain reaction (PCR) using machine learning (2021) (1)
- Identifying animal viruses in humans (2023) (1)
- ADAPTIVE EVOLUTION At the mercy of viruses Viruses are responsible for many of the adaptive mutations in the human genome (2016) (1)
- Estimating the effect of non-pharmaceutical interventions on US SARS-CoV-2 infections in the first year of the pandemic (2022) (0)
- Predicting virus-receptor mutant binding by molecular dynamics simulation (2013) (0)
- Editor's evaluation: Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor (2021) (0)
- Control of Genetic Parasites Mediated Through Nucleoporin Evolution (2017) (0)
- 157. Variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins (2015) (0)
- Reply to Schmitt et al.: Data-filtering schemes for avoiding double-counting in circle sequencing (2014) (0)
- Positive natural selection in primate genes of the type I interferon response (2021) (0)
- Author response: Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats (2015) (0)
- Using SNPs to study complex genetic disease : A population and evolutionary genetics perspective (2004) (0)
- Correction: Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes (2018) (0)
- Author response: Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir (2018) (0)
- Structurally divergent and recurrently mutated regions of primate genomes (2023) (0)
- How avian influenza viruses spill over to mammals (2023) (0)
- move Over Retroviruses:trim5 Is A Potent Restriction Factor For Tick-borne Flaviviruses : p151 (2016) (0)
- Nuku, a family of primate retrogenes derived from KU70 (2020) (0)
- The Wolbachia infection frequency of insects in central West Virginia (2017) (0)
- Notable science quotes (2016) (0)
- Human ACE2 Polymorphisms from Different Human Populations Modulate SARS-CoV-2 Infection (2022) (0)
- S UPPLEMENTAL M ATERIALS FOR A M ETA - ANALYSIS OF B AT P HYLOGENETICS B ASED ON W HOLE G ENOMES AND T RANSCRIPTOMES FROM 18 SPECIES (2019) (0)
- Nuku, a family of primate retrocopies derived from KU70 (2021) (0)
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