Sara Snogerup Linse
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Swedish chemist
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Chemistry
Sara Snogerup Linse's Degrees
- PhD Chemistry Lund University
Why Is Sara Snogerup Linse Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sara Snogerup Linse is a Swedish Professor of Biochemistry at Lund University. Her research considers the molecular mechanisms of protein self-assembly in Alzheimer's disease. She serves as Chair of the Committee for the Nobel Prize in Chemistry. She was awarded the 2019 European Molecular Biology Organization Women in Science Award.
Sara Snogerup Linse's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles (2007) (2603)
- Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism (2013) (1037)
- Nucleation of protein fibrillation by nanoparticles (2007) (776)
- Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. (2007) (771)
- The nanoparticle-protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century. (2007) (662)
- Methods for the detection and analysis of protein–protein interactions (2007) (572)
- Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils. (2016) (565)
- Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation (2014) (494)
- On the lag phase in amyloid fibril formation (2015) (478)
- Inhibition of amyloid beta protein fibrillation by polymeric nanoparticles. (2008) (437)
- Molecular mechanisms of protein aggregation from global fitting of kinetic models (2016) (430)
- Calcium binding to calmodulin and its globular domains. (1991) (419)
- Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain (2017) (379)
- Systematic investigation of the thermodynamics of HSA adsorption to N-iso-propylacrylamide/N-tert-butylacrylamide copolymer nanoparticles. Effects of particle size and hydrophobicity. (2007) (355)
- Altered behavior, physiology, and metabolism in fish exposed to polystyrene nanoparticles. (2015) (353)
- Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides (2014) (347)
- Food Chain Transport of Nanoparticles Affects Behaviour and Fat Metabolism in Fish (2012) (343)
- Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process. (2010) (339)
- Conversion of alpha-lactalbumin to a protein inducing apoptosis. (2000) (333)
- Modeling the Time Evolution of the Nanoparticle-Protein Corona in a Body Fluid (2010) (304)
- The molecular chaperone Brichos breaks the catalytic cycle that generates toxic Aβ oligomers (2015) (261)
- Acceleration of α-Synuclein Aggregation by Exosomes* (2014) (251)
- A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide (2009) (249)
- Complete high‐density lipoproteins in nanoparticle corona (2009) (243)
- Detecting Cryptic Epitopes Created by Nanoparticles (2006) (235)
- Dual effect of amino modified polystyrene nanoparticles on amyloid β protein fibrillation. (2010) (229)
- Secondary nucleation in amyloid formation. (2018) (196)
- Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation (2016) (187)
- Molecular Characterization of α–Lactalbumin Folding Variants That Induce Apoptosis in Tumor Cells* (1999) (185)
- Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease (2016) (167)
- An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease (2016) (165)
- HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects. (2003) (161)
- Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes (2018) (150)
- Surface effects on aggregation kinetics of amyloidogenic peptides. (2014) (141)
- Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex (2008) (140)
- Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease (2019) (137)
- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (2020) (136)
- Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation* (2014) (133)
- The nanoparticle protein corona formed in human blood or human blood fractions (2017) (133)
- The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model. (2016) (132)
- Determinants that govern high-affinity calcium binding. (1995) (130)
- Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification (2017) (130)
- α‐Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human α‐lactalbumin made lethal to tumor cells) (2003) (128)
- The Effect of Nanoparticles on Amyloid Aggregation Depends on the Protein Stability and Intrinsic Aggregation Rate (2011) (128)
- BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide* (2012) (128)
- Electrostatic contributions to the binding of Ca2+ in calbindin D9k. (1991) (127)
- The role of protein surface charges in ion binding (1988) (125)
- Inhibition of IAPP and IAPP(20-29) fibrillation by polymeric nanoparticles. (2010) (122)
- Calbindin D28k Exhibits Properties Characteristic of a Ca2+ Sensor* (2002) (118)
- Salting the charged surface: pH and salt dependence of protein G B1 stability. (2006) (113)
- Semenogelins I and II bind zinc and regulate the activity of prostate-specific antigen. (2005) (109)
- Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay. (2014) (109)
- Lipids as cofactors in protein folding: Stereo‐specific lipid–protein interactions are required to form HAMLET (human α‐lactalbumin made lethal to tumor cells) (2003) (108)
- Structure-function relationships in EF-hand Ca2+-binding proteins. Protein engineering and biophysical studies of calbindin D9k. (1987) (108)
- Residue-specific pKa determination of lysine and arginine side chains by indirect 15N and 13C NMR spectroscopy: application to apo calmodulin. (2007) (101)
- Protein microgels from amyloid fibril networks. (2015) (99)
- Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates (2019) (98)
- Structural changes in apolipoproteins bound to nanoparticles. (2011) (98)
- Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method (2017) (95)
- Membrane interaction of α-synuclein in different aggregation states. (2011) (93)
- Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide (2018) (92)
- Membrane Lipid Co-Aggregation with α-Synuclein Fibrils (2013) (92)
- Monomer-dependent secondary nucleation in amyloid formation (2017) (91)
- Role of aromatic side chains in amyloid β-protein aggregation. (2012) (90)
- High Resolution Structural Characterization of Aβ42 Amyloid Fibrils by Magic Angle Spinning NMR (2015) (89)
- Measurement of Ca2+-binding constants of proteins and presentation of the CaLigator software. (2002) (89)
- Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes (2019) (86)
- Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions. (2016) (84)
- A folding variant of α‐lactalbumin with bactericidal activity against Streptococcus pneumoniae (2000) (83)
- Battle for the EF-hands: magnesium-calcium interference in calmodulin. (1999) (81)
- Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide (2016) (81)
- Physical determinants of the self-replication of protein fibrils (2016) (80)
- Conversion of a-lactalbumin to a protein inducing apoptosis (2000) (79)
- Calmodulin binding to the polybasic C-termini of STIM proteins involved in store-operated calcium entry. (2008) (79)
- The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02517b Click here for additional data file. (2015) (79)
- Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin. (2007) (79)
- On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations (2018) (78)
- Mutational effects on the cooperativity of Ca2+ binding in calmodulin. (1993) (77)
- Structural basis for the negative allostery between Ca2+‐ and Mg2+ ‐binding in the intracellular Ca2+ ‐receptor calbindin D9k (1997) (77)
- Cooperativity: over the Hill. (1995) (77)
- Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics. (2013) (75)
- Calcium binding to the isolated beta-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X. (1989) (75)
- 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. (2006) (74)
- myo-Inositol Monophosphatase Is an Activated Target of Calbindin D28k* (2002) (74)
- Size-dependent effects of nanoparticles on enzymes in the blood coagulation cascade. (2014) (73)
- Isolated Hypervariable Regions Derived from Streptococcal M Proteins Specifically Bind Human C4b-Binding Protein: Implications for Antigenic Variation1 (2001) (73)
- Polystyrene nanoparticles affecting blood coagulation. (2012) (71)
- Novel type of very high affinity calcium-binding sites in beta-hydroxyasparagine-containing epidermal growth factor-like domains in vitamin K-dependent protein S. (1990) (71)
- Kinetic diversity of amyloid oligomers (2020) (70)
- Calcium binding to the epidermal growth factor homology region of bovine protein C. (1988) (70)
- The BRICHOS domain, amyloid fibril formation, and their relationship. (2013) (69)
- Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies. (2014) (66)
- Measurement and modelling of sequence-specific pKa values of lysine residues in calbindin D9k. (1996) (65)
- Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies (2020) (65)
- Retardation of Abeta fibril formation by phospholipid vesicles depends on membrane phase behavior. (2010) (65)
- Extreme Sequence Divergence but Conserved Ligand-Binding Specificity in Streptococcus pyogenes M Protein (2006) (64)
- Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy (2010) (59)
- Isolation and Detection of Human IgA Using a Streptococcal IgA-Binding Peptide1 (2002) (59)
- Stability of HAMLET—A kinetically trapped α‐lactalbumin oleic acid complex (2005) (59)
- High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria (2012) (56)
- Protein reconstitution and three‐dimensional domain swapping: Benefits and constraints of covalency (2007) (55)
- The role of electrostatic interactions in calmodulin-peptide complex formation. (2004) (55)
- N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42. (2015) (52)
- Protein surface charges and Ca2+ binding to individual sites in calbindin D9k: stopped-flow studies. (1990) (51)
- The chaperone-like activity of a small heat shock protein is lost after sulfoxidation of conserved methionines in a surface-exposed amphipathic alpha-helix. (2001) (51)
- Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity. (2015) (49)
- Charge dependent retardation of amyloid β aggregation by hydrophilic proteins. (2014) (49)
- Integrated Protein Array Screening and High Throughput Validation of 70 Novel Neural Calmodulin-binding Proteins* (2010) (48)
- Quantitative measurements of the cooperativity in an EF‐hand protein with sequential calcium binding (1995) (47)
- The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogaster (2014) (47)
- Mechanism of amyloid protein aggregation and the role of inhibitors (2019) (46)
- Ganglioside lipids accelerate α-synuclein amyloid formation (2018) (46)
- Scaling behaviour and rate-determining steps in filamentous self-assembly† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01965c Click here for additional data file. (2017) (46)
- Three-Dimensional Tracking of Small Aquatic Organisms Using Fluorescent Nanoparticles (2013) (46)
- SAR by kinetics for drug discovery in protein misfolding diseases (2018) (45)
- Binding site for C4b-binding protein in vitamin K-dependent protein S fully contained in carboxy-terminal laminin-G-type repeats. A study using recombinant factor IX-protein S chimeras and surface plasmon resonance. (1997) (45)
- Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication (2017) (45)
- Specific binding of a β-cyclodextrin dimer to the amyloid β peptide modulates the peptide aggregation process. (2012) (44)
- pK(a) values for side-chain carboxyl groups of a PGB1 variant explain salt and pH-dependent stability. (2007) (43)
- Quantitative determination of the radius of gyration of poly(methyl methacrylate) in the amorphous solid state by time-resolved fluorescence depolarization measurements of excitation transport (1987) (43)
- Calbindin-D28K, a 1 alpha,25-dihydroxyvitamin D3-induced calcium-binding protein, binds five or six Ca2+ ions with high affinity. (1990) (43)
- Fragment complementation studies of protein stabilization by hydrophobic core residues. (2001) (42)
- The effect of protein concentration on ion binding. (1995) (42)
- Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc00215g Click here for additional data file. (2017) (42)
- Calcium binding and thermostability of carbohydrate binding module CBM4-2 of Xyn10A from Rhodothermus marinus. (2002) (42)
- Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes (2015) (41)
- Streptococcal M protein: structural studies of the hypervariable region, free and bound to human C4BP. (2006) (41)
- Ca(2+)- and H(+)-dependent conformational changes of calbindin D(28k). (2000) (40)
- A Region of Vitamin K-dependent Protein S That Binds to C4b Binding Protein (C4BP) Identified Using Bacteriophage Peptide Display Libraries* (1997) (40)
- Both G-type domains of protein S are required for the high-affinity interaction with C4b-binding protein. (1999) (40)
- The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils (2020) (40)
- Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening. (2012) (40)
- Electrostatic contributions to the kinetics and thermodynamics of protein assembly. (2005) (39)
- Compact oleic acid in HAMLET (2005) (39)
- Dynamics of conformational Ca2+-switches in signaling networks detected by a planar plasmonic device. (2012) (39)
- Ionization Behavior of Acidic Residues in Calbindin D9k (1999) (39)
- The first epidermal growth factor-like domain of the low-density lipoprotein receptor contains a noncanonical calcium binding site. (2001) (39)
- Disulfide bonds in homo‐ and heterodimers of EF‐hand subdomains of calbindin D9k: Stability, calcium binding, and NMR studies (1993) (39)
- Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion. (2011) (38)
- SHBG region of the anticoagulant cofactor protein S: Secondary structure prediction, circular dichroism spectroscopy, and analysis of naturally occurring mutations (1997) (37)
- Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer’s Disease? (2015) (37)
- Calcium binding to proteins studied via competition with chromophoric chelators. (2002) (37)
- Domain organization of calbindin D28k as determined from the association of six synthetic EF‐hand fragments (1997) (37)
- Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates (2017) (35)
- Protein reconstitution and 3D domain swapping. (2002) (34)
- Effect of amino acid substitutions and deletions on the thermal stability, the pH stability and unfolding by urea of bovine calbindin D9k. (1988) (34)
- An extended hudrophobic core induces EF‐hand swapping (2001) (34)
- Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation. (2018) (33)
- Role of protein surface charge in monellin sweetness. (2009) (33)
- A peptide from human semenogelin I self-assembles into a pH-responsive hydrogel. (2015) (33)
- The High Affinity Calcium-binding Sites in the Epidermal Growth Factor Module Region of Vitamin K-dependent Protein S* (1997) (32)
- A Proline-Rich Region with a Highly Periodic Sequence in Streptococcal β Protein Adopts the Polyproline II Structure and Is Exposed on the Bacterial Surface (2002) (32)
- Ca2+ binding to calbindin D9k strongly affects backbone dynamics: measurements of exchange rates of individual amide protons using 1H NMR. (1990) (32)
- Mastoparan binding induces a structural change affecting both the N‐terminal and C‐terminal domains of calmodulin (1986) (32)
- Coupling of ligand binding and dimerization of helix‐loop‐helix peptides: Spectroscopic and sedimentation analyses of calbindin D9k EF‐hands (2002) (31)
- Intra- versus intermolecular interactions in monellin: contribution of surface charges to protein assembly. (2006) (31)
- Ca2+-binding stoichiometry of calbindin D28k as assessed by spectroscopic analyses of synthetic peptide fragments. (1996) (31)
- Structural Requirements of Anticoagulant Protein S for Its Binding to the Complement Regulator C4b-binding Protein* (2002) (31)
- Translocation of 40 nm diameter nanowires through the intestinal epithelium of Daphnia magna (2016) (31)
- Focusing of the electrostatic potential at EF‐hands of calbindin D9k: Titration of acidic residues (2001) (30)
- Identification of on- and off-pathway oligomers in amyloid fibril formation (2020) (30)
- Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid (2019) (30)
- Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells. (2002) (30)
- Electrostatic contributions to residue-specific protonation equilibria and proton binding capacitance for a small protein. (2006) (30)
- Monte Carlo simulations of protein amyloid formation reveal origin of sigmoidal aggregation kinetics. (2011) (29)
- On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products. (2017) (29)
- Biocompatibility of mannan nanogel--safe interaction with plasma proteins. (2012) (29)
- Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation. (1998) (28)
- Effects of Polyamino Acids and Polyelectrolytes on Amyloid β Fibril Formation (2014) (26)
- Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation (2020) (26)
- In vivo protein stabilization based on fragment complementation and a split GFP system (2010) (26)
- Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors (2020) (26)
- Site-specific protonation kinetics of acidic side chains in proteins determined by pH-dependent carboxyl (13)C NMR relaxation. (2015) (26)
- Hydrophobic core substitutions in calbindin D9k: effects on stability and structure. (1998) (26)
- Domain Identification of Hormone-sensitive Lipase by Circular Dichroism and Fluorescence Spectroscopy, Limited Proteolysis, and Mass Spectrometry* (1999) (25)
- Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils (2019) (25)
- Kinetics of calcium binding to calbindin mutants. (1988) (25)
- Fluorescent Filter-Trap Assay for Amyloid Fibril Formation Kinetics in Complex Solutions (2015) (25)
- Multi‐method global analysis of thermodynamics and kinetics in reconstitution of monellin (2004) (25)
- Reconstitution of calmodulin from domains and subdomains: Influence of target peptide. (2006) (24)
- An EF-hand phage display study of calmodulin subdomain pairing. (2000) (24)
- The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain. (2019) (24)
- Ion-binding properties of calbindin D9k: a Monte Carlo simulation study. (1991) (24)
- Calbindin D(9k): a protein optimized for calcium binding at neutral pH. (2001) (24)
- Salt enhances calmodulin-target interaction. (2006) (23)
- A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions. (2016) (23)
- Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils (2020) (23)
- Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems. (2014) (22)
- Fragment complementation of calbindin D28k (2000) (22)
- Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele (2016) (22)
- Chemical and thermal unfolding of glypican-1: protective effect of heparan sulfate against heat-induced irreversible aggregation. (2009) (21)
- Calmodulin transduces Ca2+ oscillations into differential regulation of its target proteins. (2013) (21)
- Deamidation and disulfide bridge formation in human calbindin D28k with effects on calcium binding (2005) (21)
- Kinetics of cadmium and terbium dissociation from calmodulin and its tryptic fragments. (1986) (21)
- Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter (2020) (20)
- The Aggregation Paths and Products of Aβ42 Dimers Are Distinct from Those of the Aβ42 Monomer. (2016) (20)
- Molecular design of specific metal-binding peptide sequences from protein fragments: theory and experiment. (2008) (20)
- Synthesis of an N-linked glycopeptide from vitamin K-dependent protein S (1998) (19)
- The catalytic nature of protein aggregation (2020) (19)
- Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant. (2017) (19)
- Aggregation and Fibril Structure of AβM01-42 and Aβ1-42. (2017) (18)
- Green fluorescence induced by EF‐hand assembly in a split GFP system (2009) (18)
- On the Mechanism of Self-Assembly by a Hydrogel-Forming Peptide. (2020) (17)
- A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (17)
- Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation. (2021) (16)
- Structural properties of semenogelin I (2007) (16)
- A general reaction network unifies the aggregation behaviour of the A$\beta$42 peptide and its variants (2016) (15)
- Charge Regulation during Amyloid Formation of α-Synuclein (2021) (15)
- Atomic Resolution Structure of Monomorphic Aβ₄₂ Amyloid Fibrils (2016) (15)
- Zn2+ binding to human calbindin D28k and the role of histidine residues (2008) (14)
- Charting a course for chemistry (2019) (14)
- The Modular Organisation and Stability of a Thermostable Family 10 Xylanase (2003) (14)
- Protein GB1 Folding and Assembly from Structural Elements (2009) (14)
- Molecular Determinants of S100B Oligomer Formation (2011) (14)
- Conformational Ensembles of Calmodulin Revealed by Nonperturbing Site-Specific Vibrational Probe Groups (2018) (14)
- A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution. (2015) (14)
- Binding of Ca2+ to calbindin D9k: structural stability and function at high salt concentration. (1994) (14)
- Redox sensitive cysteine residues in calbindin D28k are structurally and functionally important. (2005) (14)
- Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation. (2016) (14)
- Kinetic Analysis of Amyloid Formation. (2018) (14)
- Effects of metal-binding loop mutations on ligand binding to calcium- and integrin-binding protein 1. Evolution of the EF-hand? (2008) (14)
- Anomalous Salt Dependence Reveals an Interplay of Attractive and Repulsive Electrostatic Interactions in α-synuclein Fibril Formation (2020) (13)
- Binding of calcium to anticoagulant protein S: role of the fourth EGF module. (2006) (13)
- Protein folding through kinetic discrimination. (2007) (13)
- Protein-protein interactions in AQP regulation - biophysical characterization of AQP0-CaM and AQP2-LIP5 complex formation. (2018) (13)
- Ionic strength effects on the binding constant of calcium chelators: experiment and theory (1992) (13)
- Ca2+ binding in proteins of the calmodulin superfamily: cooperativity, electrostatic contributions and molecular mechanisms. (1991) (13)
- A folding variant of α‐lactalbumin with bactericidal activity against Streptococcus pneumoniae (2000) (13)
- Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42. (2019) (13)
- Probing calmodulin protein-protein interactions using high-content protein arrays. (2011) (12)
- The structural role of N-linked glycans on human glypican-1. (2011) (12)
- Cyanylated Cysteine Reports Site-Specific Changes at Protein–Protein-Binding Interfaces Without Perturbation (2018) (12)
- pK(a) values for the unfolded state under native conditions explain the pH-dependent stability of PGB1. (2010) (12)
- Proton-Assisted Recoupling (PAR) in Peptides and Proteins. (2017) (12)
- High Throughput Screening Method to Explore Protein Interactions with Nanoparticles (2015) (11)
- Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid (2019) (11)
- Förster resonance energy transfer studies of calmodulin produced by native protein ligation reveal inter‐domain electrostatic repulsion (2013) (11)
- Interactions in the native state of monellin, which play a protective role against aggregation. (2011) (11)
- Digested wheat gluten inhibits binding between leptin and its receptor (2015) (11)
- Haemophilus influenzae surface fibril (Hsf) is a unique twisted hairpin-like trimeric autotransporter. (2015) (11)
- Fibril Charge Affects α-Synuclein Hydrogel Rheological Properties. (2019) (11)
- Calbindin D28k EF-hand ligand binding and oligomerization: four high-affinity sites--three modes of action. (2005) (11)
- 3D MAS NMR Experiment Utilizing Through-Space 15N-15N Correlations. (2017) (11)
- Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates (2021) (11)
- Calcium Binding and Disulfide Bonds Regulate the Stability of Secretagogin towards Thermal and Urea Denaturation (2016) (11)
- Expression and purification of human calbindin D28k. (1999) (11)
- Expression, purification and characterisation of large quantities of recombinant human IAPP for mechanistic studies. (2020) (10)
- Disaggregation of gold nanoparticles by Daphnia magna (2018) (10)
- Galectin-3, A Novel Endogenous Trem2 Ligand, Regulates Inflammatory Response and Aβ Fibrilation in Alzheimer’s Disease (2018) (10)
- Lipid-protein interactions in amyloid formation. (2019) (10)
- Kinetic fingerprint of antibody therapies predicts outcomes of Alzheimer clinical trials (2019) (10)
- Amyloid β 42 fibril structure based on small-angle scattering (2021) (9)
- Rapid and Facile Purification of Apolipoprotein A-I from Human Plasma Using Thermoresponsive Nanoparticles (2011) (9)
- A calbindin D9k mutant with reduced calcium affinity and enhanced cooperativity. Metal ion binding, stability, and structural studies. (1994) (9)
- Simplifying G Protein-Coupled Receptor Isolation with a Calcium-Dependent Fragment Complementation Affinity System. (2018) (9)
- Production and physicochemical characterization of acidocin D20079, a bacteriocin produced by Lactobacillus acidophilus DSM 20079 (2007) (9)
- 1H detection and dynamic nuclear polarization–enhanced NMR of Aβ1-42 fibrils (2021) (9)
- Transient Lipid-Protein Structures and Selective Ganglioside Uptake During α-Synuclein-Lipid Co-aggregation (2021) (9)
- Symmetrical stabilization of bound Ca2+ ions in a cooperative pair of EF-hands through hydrogen bonding of coordinating water molecules in calbindin D(9k). (2001) (8)
- Binding of charged ligands to macromolecules. Anomalous salt dependence. (2005) (8)
- Cooperativity of α-Synuclein Binding to Lipid Membranes (2021) (8)
- Epidermal Growth Factor‐like Domains in the Vitamin K‐Dependent Clotting Factors (1991) (8)
- A microfluidic strategy for the detection of membrane protein interactions. (2020) (8)
- Erratum: A folding variant of α-lactalbumin with bactericidal activity against Streptococcus pneumoniae (Molecular Microbiology, 35, 3 (589-600)) (2000) (8)
- Calcium nuclear magnetic resonance. (1993) (8)
- Calcium-dependent interaction of calmodulin with human 80S ribosomes and polyribosomes. (2012) (8)
- The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus (2019) (8)
- Truncated semenogelin I binds zinc and is cleaved by prostate-specific antigen. (2006) (8)
- Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation (2022) (8)
- Characterization of calretinin I–II as an EF‐hand, Ca2+, H+‐sensing domain (2005) (7)
- Protein networks involved in vesicle fusion, transport, and storage revealed by array-based proteomics. (2011) (7)
- The unhappy chaperone (2021) (6)
- Proliferation of Tau 304–380 Fragment Aggregates through Autocatalytic Secondary Nucleation (2021) (6)
- pH-Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide. (2021) (6)
- Expression and Purification of Intrinsically Disordered Aβ Peptide and Setup of Reproducible Aggregation Kinetics Experiment. (2020) (6)
- Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (2020) (6)
- A calbindin D9k mutant containing a novel structural extension: 1H nuclear magnetic resonance studies (1997) (5)
- Calmodulin complexes with brain and muscle creatine kinase peptides (2021) (5)
- Chiral Selectivity of Secondary Nucleation in Amyloid Fibril Propagation (2021) (4)
- Aggregate Size Dependence of Amyloid Adsorption onto Charged Interfaces (2017) (4)
- A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli (2019) (4)
- Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease (2018) (4)
- Reprint of "Ganglioside lipids accelerate α-synuclein amyloid formation". (2019) (4)
- Kinetic fingerprints differentiate anti-Aβ therapies (2019) (4)
- Acceleration of α-synuclein aggregation (2017) (4)
- Uncovering the universality of self-replication in protein aggregation and its link to disease (2022) (4)
- Protein engineering and structure/function relations in bovine calbindin D9k. (1990) (4)
- Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain (2017) (3)
- Protein stabilization with retained function of monellin using a split GFP system (2018) (3)
- The Bacterial Amyloids Phenol Soluble Modulins from Staphylococcus aureus Catalyze Alpha-Synuclein Aggregation (2021) (3)
- Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α-Synuclein Aggregates (2021) (3)
- Single Step Purification of Glycogen Synthase Kinase Isoforms from Small Scale Transient Expression in HEK293 Cells with a Calcium-Dependent Fragment Complementation System. (2020) (3)
- A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation (2022) (3)
- Letter to the Editor: Sequential 1H, 15N and 13C NMR Assignment of Human Calbindin D28k (2004) (2)
- Crystal structure of calbindin D9k binding Mg2 (1996) (2)
- Ganglioside GM3 stimulates lipid-protein co-assembly in α-synuclein amyloid formation. (2022) (2)
- An aggregation inhibitor specific to oligomeric intermediates of Aβ42 derived from phage display libraries of stable, small proteins (2022) (2)
- STRUCTURE-FUNCTION RELATIONS IN EF-HAND CA2+-BINDING PROTEINS: GENETIC ENGINEERING AND BIOPHYSICAL STUDIES OF BOVINE INTESTINAL CALCIUM PROTEIN (ICaBP) (1987) (2)
- A Palette of Fluorescent Aβ42 Peptides Labelled at a Range of Surface-Exposed Sites (2022) (2)
- Solubility of Aβ40 peptide (2021) (2)
- Thermodynamic and kinetic design principles for protein aggregation inhibitors (2020) (2)
- Production and Use of Recombinant Aβ for Aggregation Studies. (2018) (2)
- Benefits and constrains of covalency: the role of loop length in protein stability and ligand binding (2020) (2)
- Toward the equilibrium and kinetics of amyloid peptide self-assembly. (2021) (2)
- Revealing Well-Defined Soluble States during Amyloid Fibril Formation by Multilinear Analysis of NMR Diffusion Data (2019) (1)
- α-Synuclein-induced deformation of small unilamellar vesicles (2022) (1)
- Running title : HAMLET in tumor cell apoptosis Title : HAMLET KILLS TUMOR CELLS BY APOPTOSIS-CELLULAR , MOLECULAR AND THERAPEUTIC ASPECTS (2003) (1)
- Streptococcal IgA-Binding Peptide Isolation and Detection of Human IgA Using a (2002) (1)
- Ensemble Average Conformation of Isolated Polymer Coils in Solid Blends Using Electronic Excitation Transport (1987) (1)
- Influence of denaturants on amyloid β42 aggregation kinetics (2022) (1)
- Calcium‐Binding Proteins (2007) (1)
- Purification and HDL-like particle formation of apolipoprotein A-I after co-expression with the EDDIE mutant of Npro autoprotease. (2021) (1)
- A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (1)
- NANOINTERACT: A rational approach to the interaction between nanoscale materials and living matter? (2009) (1)
- Comparing α-Synuclein Fibrils Formed in the Absence and Presence of a Model Lipid Membrane: A Small and Wide-Angle X-Ray Scattering Study (2022) (0)
- This information is current as for Antigenic Variation Human C 4 b-Binding Protein : Implications Streptococcal M Proteins Specifically Bind Isolated Hypervariable Regions Derived from (2001) (0)
- Generation, characterisation and deposition of spherical and agglomerated model metal particles for protein corona and toxicological studies. (2011) (0)
- TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES (2018) (0)
- Morphology-Dependent Interactions between α-Synuclein Monomers and Fibrils (2023) (0)
- Understanding the Structural Changes of the Calcium Binding S100A1 Protein with Molecular Dynamics Simulations (2015) (0)
- The aggregation paths and products of Aβ42 dimers are distinct from Aβ42 monomer (2017) (0)
- The fate of aerosol gold nanoparticles upon deposition into physiological fluids (2010) (0)
- Neutralization of surface charges markedly affects the properties of bovine calbindin D9k. (1989) (0)
- Physics of colloidal particles with heterogeneously patterned surfaces (2014) (0)
- Decision letter: Structure-based inhibitors of amyloid beta core suggest a common interface with tau (2019) (0)
- Cyanylated Cysteine used to Characterize Binding Interfaces of Calcium Binding Proteins (2011) (0)
- Crystallization Studies of Calmodulin Binding Targets (2015) (0)
- Membrane Interaction of α-Synuclein in Different Aggregation States (2012) (0)
- On the Cluster Formation of α-Synuclein Fibrils (2021) (0)
- Direct deposition of aerosol generated AuNPs into biological buffers produce specific protein corona in lung-fluid and blood serum (2011) (0)
- Ca2+-Calmodulin in complex with human muscle form creatine kinase peptide in extended 1:2 binding mode (2021) (0)
- 3D MAS NMR Experiment Utilizing Through-Space (2017) (0)
- Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease (2023) (0)
- Mechanism of secondary nucleation from the direct observation of Aβ42 aggregation at the single fibril level (2022) (0)
- The Royal Society of r and rate-determining steps in fi lamentous self-assembly † (2017) (0)
- The fate of aerosol AuNP upon deposition into physiological fluids – Protein corona and aggregation in solution (2012) (0)
- Amyloid Beta Peptide: The Influence of Intrinsic Factors on Fibril Formation (2012) (0)
- Guest-protein incorporation into solvent channels of a protein host crystal (hostal) (2021) (0)
- Targeting the Formation of Amyloid Oligomers using Rationally Designed Antibodies (2019) (0)
- Experimental Study of Amyloidogenic Protein Adsorption to Supported Lipid Bilayers (2012) (0)
- Solubility of the amyloidogenic core of tau in CSF. (2023) (0)
- CALCIUM BINDING TO ANTICOAGULANT PROTEIN S. ROLE OF THE FOURTH EGF MODULE (2012) (0)
- Mechanisms of Amyloid-beta 42 oligomer formation from kinetic analysis (2017) (0)
- C4BP-mediated complement evasion in streptococcal infections: How the good guys turn bad (2018) (0)
- Aggregation of the amyloid-β peptide (Aβ) into toxic oligomers and amyloid fibrils is linked to the development of Alzheimer’s disease (AD). Mutations of the BRICHOS chaperone domain are associated with amyloid disease and recent in vitro data show that BRICHOS (2014) (0)
- Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (0)
- Ca2+-Calmodulin in complex with peptide from brain-type creatine kinase in extended 1:2 binding mode (2021) (0)
- P2-422: Co-polymeric nanoparticles inhibit Abeta fibrillogenesis (2008) (0)
- Towards physico-chemical understanding of fibril formation of the Alzheimer disease-associated amyloid beta-peptide (2009) (0)
- Single-vesicle intensity and colocalization fluorescence microscopy to study lipid vesicle fusion, fission, and lipid exchange (2022) (0)
- Microfluidic free-flow electrophoresis for the discovery and characterisation of calmodulin binding partners (2015) (0)
- High-Efficiency Expression and Purification of DNAJB6b Based on the pH-Modulation of Solubility and Denaturant-Modulation of Size (2022) (0)
- Ca2+-Binding in proteins of the calmodulin superfamily:Cooperativity and its molecular basis. (1991) (0)
- Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications (2020) (0)
- Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation (2020) (0)
- Role of Hydrophobicity at the N-Terminal Region of Aβ42 in Secondary Nucleation (2022) (0)
- BRICHOS domains efficiently prevent fibrillation of beta-amyloid peptide (2012) (0)
- Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp (2020) (0)
- ectrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the A b 42 peptide and its variants † (2017) (0)
- Exosomes -Synuclein Aggregation by α Acceleration of (2014) (0)
- Scaling exponents report on changes in the mechanism of filamentous growth (2012) (0)
- Amyloid β-Protein: The Influence of Intrinsic and Extrinsic Factors on Fibril Formation (2014) (0)
- Prevention of amyloid β-peptide fibrillation by the BRICHOS domain (2011) (0)
- Crystal Structure of Domain Swapped Trp Repressor V58I Variant (2020) (0)
- Aerosol Model Nanoparticles for Protein/Biomolecule Corona Determination in Physiological Buffers - Possible Means of Determining Particle Toxicity and Fate in Humans (2011) (0)
- A Study in Semenogelin I Hydrogel Aggregation Kinetics (2015) (0)
- Research data supporting "Physical determinants for the self-replication of protein fibrils" (2016) (0)
- α-Synuclein Interaction with Lipid Bilayer Discs (2022) (0)
- Protein Interaction , Association and Fibrillation (2009) (0)
- A novel direct link between Ca2+ signalling and energy homeostasis? Structural background of brain and muscle creatine kinase modulation by calmodulin (2018) (0)
- Using NProAutoprotease Fusion Technology to Express a Semenogelin I Peptide (2019) (0)
- 1H NMR Study of the Adsorption Mechanism for Ti-Binding Peptide on TiO2 Nanoparticles (2015) (0)
- On the Aggregation of Apolipoprotein A-I (2022) (0)
- Tau AD fragment aggregates proliferate through autocatalytic secondary nucleation (2021) (0)
- experim ent uti l izing through-space 1 5 N-1 5 N correlations (2017) (0)
- SPECTROSCOPIC STUDIES ON CHICK INTESTINAL CALBINDIN-D28K SUGGEST THE EXISTENCE OF 4-6 FUNCTIONAL CA2+ BINDING SITES (1988) (0)
- running head: Jonsson et al, Truncated semenogelin I binds zinc Truncated semenogelin I binds zinc and is cleaved by prostate-specific antigen (2006) (0)
- Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (2021) (0)
- Investigations into the Mechanism of Fibril Formation in a Peptide Hydrogel (2019) (0)
- Protein interactions with the surface of gold nanoparticles: possible means of determining particle toxicity (2012) (0)
- A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation (2022) (0)
- Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes (2019) (0)
- Monomer-dependent secondary nucleation in amyloid formation (2017) (0)
- THE NOVEL EFFECT OF CSF AND APOE4 ON THE AGGREGATION KINETICS OF Aβ42 IN ALZHEIMER'S DISEASE (2014) (0)
- DOMAIN SWAPPING EF-HANDS (2001) (0)
- A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli (2019) (0)
- Protein stabilization with retained function of monellin using a split GFP system (2018) (0)
- Phase Boundaries for Fibril and Metastable Oligomer Formation ofLysozyme (2014) (0)
- BIOL 52-Calmodulin: Site specific chromophore labeling to monitor conformational transitions (2008) (0)
- Aerosol deposition of AuNP into biological fluids produce specific biomolecule corona (2011) (0)
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