Sarah Elgin
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American biologist
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Sarah Elginbiology Degrees
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Genetics
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Biology
Sarah Elgin's Degrees
- PhD Biology University of California, San Diego
- Bachelors Biology University of California, Santa Cruz
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Why Is Sarah Elgin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sarah C.R. Elgin is an American biochemist and geneticist. She is the Viktor Hamburger Professor of biology at Washington University in St. Louis, and is noted for her work in epigenetics, gene regulation, and heterochromatin, and for her contributions to science education.
Sarah Elgin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE (2010) (1211)
- Epigenetic Codes for Heterochromatin Formation and Silencing Rounding up the Usual Suspects (2002) (881)
- Comprehensive analysis of the chromatin landscape in Drosophila (2010) (868)
- Heterochromatic Silencing and HP1 Localization in Drosophila Are Dependent on the RNAi Machinery (2004) (714)
- Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. (1990) (574)
- Chromosomal proteins and chromatin structure. (1975) (547)
- The HP1 protein family: getting a grip on chromatin. (2000) (497)
- Position effect variegation in Drosophila is associated with an altered chromatin structure. (1995) (496)
- Transcription and RNA interference in the formation of heterochromatin (2007) (459)
- Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila. (1989) (428)
- Heterochromatin: new possibilities for the inheritance of structure. (2002) (419)
- Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila. (2013) (394)
- An assessment of histone-modification antibody quality (2010) (387)
- A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students (2014) (371)
- Drosophila PIWI associates with chromatin and interacts directly with HP1a. (2007) (365)
- The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence (1979) (347)
- Comparative analysis of metazoan chromatin organization (2014) (325)
- DNAase I-hypersensitive sites of chromatin (1981) (325)
- The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity (1979) (315)
- The formation and function of DNase I hypersensitive sites in the process of gene activation. (1988) (310)
- Polycomb silencing blocks transcription initiation. (2004) (288)
- Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity (2015) (249)
- Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. (2011) (245)
- (CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene (1993) (242)
- Heterochromatin and gene regulation in Drosophila. (1996) (233)
- A histone variant, H2AvD, is essential in Drosophila melanogaster. (1992) (219)
- Changing the Culture of Science Education at Research Universities (2011) (219)
- Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line (2011) (217)
- Heterochromatin: silence is golden (2003) (212)
- Selected topics in chromatin structure. (1985) (196)
- Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. (1984) (195)
- The contradictory definitions of heterochromatin: transcription and silencing (2006) (182)
- DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription. (1981) (175)
- The Genomics Education Partnership: Successful Integration of Research into Laboratory Classes at a Diverse Group of Undergraduate Institutions (2010) (175)
- Drosophila nuclear proteins bind to regions of alternating C and T residues in gene promoters. (1989) (174)
- Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. (1993) (173)
- Nature and function of insulator protein binding sites in the Drosophila genome (2012) (167)
- The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains. (2000) (165)
- Protein/DNA architecture of the DNase I hypersensitive region of the Drosophila hsp26 promoter. (1988) (162)
- Putting Boundaries on Silence (1999) (154)
- HP1a: a structural chromosomal protein regulating transcription. (2014) (153)
- Architectural variations of inducible eukaryotic promoters: Preset and remodeling chromatin structures (1994) (152)
- Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles (1999) (147)
- Chromatin: Ga-ga over GAGA factor (1995) (145)
- Long-Range Nucleosome Ordering Is Associated with Gene Silencing in Drosophila melanogaster Pericentric Heterochromatin (2001) (143)
- Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution (2011) (140)
- Comparative analysis of metazoan chromatin (2014) (137)
- Chromatin Structure and Gene Activity: The Role of Nonhistone Chromosomal Protein (1982) (131)
- A Course-Based Research Experience: How Benefits Change with Increased Investment in Instructional Time (2014) (128)
- Genomics Education Partnership (2008) (119)
- Boundary functions in the control of gene expression. (1991) (113)
- Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin (1987) (112)
- cis-Acting Determinants of Heterochromatin Formation on Drosophila melanogaster Chromosome Four (2004) (108)
- A histone protease of rat liver chromatin. (1972) (101)
- Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin (1998) (96)
- A method for determination of the in situ distribution of chromosomal proteins. (1976) (96)
- Nucleosome positioning and gene regulation (1994) (93)
- Multiple SET Methyltransferases Are Required to Maintain Normal Heterochromatin Domains in the Genome of Drosophila melanogaster (2009) (90)
- Multiple isoforms of GAGA factor, a critical component of chromatin structure. (1997) (88)
- Micrococcal nuclease as a probe of DNA sequence organization and chromatin structure (1981) (87)
- Element 1360 and RNAi Components Contribute to HP1-Dependent Silencing of a Pericentric Reporter (2006) (87)
- Chromatin organization and transcriptional control of gene expression in Drosophila. (2000) (86)
- Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution (2015) (82)
- Chromatin structure and gene activity. (1990) (79)
- Drosophila has a single copy of the gene encoding a highly conserved histone H2A variant of the H2A.F/Z type. (1988) (78)
- Ectopic assembly of heterochromatin in Drosophila melanogaster triggered by transposable elements (2012) (78)
- Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats. (1990) (75)
- Molecular biology: Anatomy of hypersensitive sites (1984) (72)
- Maternal Depletion of Piwi, a Component of the RNAi System, Impacts Heterochromatin Formation in Drosophila (2013) (72)
- Nucleosomal instability and induction of new upstream protein-DNA associations accompany activation of four small heat shock protein genes in Drosophila melanogaster (1986) (72)
- Cluster K Mycobacteriophages: Insights into the Evolutionary Origins of Mycobacteriophage TM4 (2011) (68)
- Bioinformatics core competencies for undergraduate life sciences education (2017) (68)
- Regulating genes by packaging domains: bits of heterochromatin in euchromatin? (1993) (66)
- Promoter sequence containing (CT)n.(GA)n repeats is critical for the formation of the DNase I hypersensitive sites in the Drosophila hsp26 gene. (1992) (66)
- Cleavage of chromatin with methidiumpropyl-EDTA . iron(II). (1983) (66)
- A high-mobility-group protein and its cDNAs from Drosophila melanogaster. (1992) (65)
- GAGA Factor and the TFIID Complex Collaborate in Generating an Open Chromatin Structure at the Drosophila melanogaster hsp26 Promoter (2002) (65)
- Points of view: effective partnerships between K-12 and higher education. (2005) (62)
- The dot chromosome of Drosophila: Insights into chromatin states and their change over evolutionary time (2006) (58)
- The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners (2011) (55)
- Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains (2006) (55)
- Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain (2012) (54)
- An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. (1997) (54)
- Raising large quantities of Drosophila for biochemical experiments. (1994) (54)
- Analysis of chromatin structure and DNA sequence organization: use of the 1,10-phenanthroline-cuprous complex. (1982) (53)
- Heterochromatin protein 2 (HP2), a partner of HP1 in Drosophila heterochromatin (2002) (52)
- A Central Support System Can Facilitate Implementation and Sustainability of a Classroom-Based Undergraduate Research Experience (CURE) in Genomics (2014) (51)
- Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context (2012) (50)
- Distribution patterns of three subfractions of drosophila nonhistone chromosomal proteins: possible correlations with gene activity (1977) (49)
- A lot about a little dot - lessons learned from Drosophila melanogaster chromosome 4. (2009) (44)
- Small RNA-directed heterochromatin formation in the context of development: what flies might learn from fission yeast. (2009) (42)
- Micrococcal nuclease as a DNA structural probe: its recognition sequences, their genomic distribution and correlation with DNA structure determinants. (1986) (42)
- Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction (2017) (41)
- Chromatin boundaries: Punctuating the genome (1998) (41)
- An inquiry into protein structure and genetic disease: introducing undergraduates to bioinformatics in a large introductory course. (2005) (40)
- Insights from a Convocation: Integrating Discovery-Based Research into the Undergraduate Curriculum (2016) (40)
- Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved in Drosophila. (1992) (39)
- Multiple forms and cellular localization of Drosophila DNA topoisomerase II. (1986) (35)
- Evolution of a Distinct Genomic Domain in Drosophila: Comparative Analysis of the Dot Chromosome in Drosophila melanogaster and Drosophila virilis (2010) (34)
- Chromatin structure, DNA structure (1982) (33)
- Monoclonal antibodies against a specific nonhistone chromosomal protein of Drosophila associated with active genes (1981) (29)
- Analysis of Drosophila chromatin structure in vivo. (1999) (29)
- Chromatin structure and gene expression (1995) (29)
- Drosophila RISC Component VIG and Its Homolog Vig2 Impact Heterochromatin Formation (2009) (28)
- The Drosophila Dot Chromosome: Where Genes Flourish Amidst Repeats (2018) (28)
- Distribution studies on polytene chromosomes using antibodies directed against hnRNP (1981) (28)
- UV cross-linking identifies four polypeptides that require the TATA box to bind to the Drosophila hsp70 promoter (1990) (28)
- A Distinct Type of Heterochromatin Within Drosophila melanogaster Chromosome 4 (2007) (28)
- An Investigation of Heterochromatin Domains on the Fourth Chromosome of Drosophila melanogaster (2008) (27)
- Chromatin structure and gene activity: the role of nonhistone chromosomal proteins. (1982) (27)
- Immunofluorescent staining of polytene chromosomes: exploiting genetic tools. (2004) (27)
- TATA box-dependent protein-DNA interactions are detected on heat shock and histone gene promoters in nuclear extracts derived from Drosophila melanogaster embryos (1988) (27)
- Functional organization of the nucleus: a laboratory guide. (1991) (27)
- Patterns of DNA structural polymorphism and their evolutionary implications (1984) (27)
- DNase I hypersensitive sites of the chromatin for Drosophila melanogaster ribosomal protein 49 gene. (1981) (26)
- DNA representation of variegating heterochromatic P-element inserts in diploid and polytene tissues ofDrosophila melanogaster (1996) (26)
- A Drosophila melanogaster H3.3 cDNA encodes a histone variant identical with the vertebrate H3.3. (1991) (26)
- A role for RNAi in heterochromatin formation in Drosophila. (2008) (25)
- Supercoil-dependent features of DNA structure at Drosophila locus 67B1. (1984) (25)
- Interaction of heterochromatin protein 2 with HP1 defines a novel HP1-binding domain. (2005) (25)
- NIBLSE: A Network for Integrating Bioinformatics into Life Sciences Education (2015) (25)
- THE GENETICS SOCIETY OF AMERICA. (1942) (25)
- Chromatin: Pushing nucleosomes around (1996) (25)
- Conservation of intron position indicates separation of major and variant H2As is an early event in the evolution of eukaryotes (1990) (25)
- Characterization of a supercoil-dependent S1 sensitive site 5' to the Drosophila melanogaster hsp 26 gene. (1986) (24)
- Immunofluorescent techniques in the analysis of chromosomal proteins. (1978) (24)
- Chemical footprinting of 5S RNA chromatin in embryos of Drosophila melanogaster. (1984) (23)
- The capacity to form H-DNA cannot substitute for GAGA factor binding to a (CT)n*(GA)n regulatory site. (2003) (23)
- Chromatin structure in pre- and postblastula embryos of Drosophila. (1983) (20)
- Heterochromatin Protein 1a (HP1a) Partner Specificity Is Determined by Critical Amino Acids in the Chromo Shadow Domain and C-terminal Extension* (2013) (20)
- [18] Nonenzymatic cleavage of chromatin (1989) (19)
- DNase I Hypersensitive Sites: A Structural Feature of Chromatin Associated with Gene Expression (1985) (19)
- Molecular biology: Antagonizing the neighbours (2005) (19)
- The Large Isoform of Drosophila melanogaster Heterochromatin Protein 2 Plays a Critical Role in Gene Silencing and Chromosome Structure (2006) (18)
- Hsp28stl: a P-element insertion mutation that alters the expression of a heat shock gene in Drosophila melanogaster. (1987) (18)
- The GEP: Crowd-Sourcing Big Data Analysis with Undergraduates. (2017) (18)
- Heterochromatin protein 2 interacts with Nap-1 and NURF: a link between heterochromatin-induced gene silencing and the chromatin remodeling machinery in Drosophila. (2006) (18)
- Heterochromatin and Euchromatin (2014) (17)
- Analyzing heterochromatin formation using chromosome 4 of Drosophila melanogaster. (2004) (16)
- Nucleosome repeat structure is present in native salivary chromosomes of Drosophila melanogaster (1982) (16)
- Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element (2017) (15)
- Preparation of Drosophila nuclei. (1994) (15)
- Defining epigenetic states through chromatin and RNA (2005) (14)
- The CourseSource Bioinformatics Learning Framework (2016) (13)
- A cytological approach to the ordering of events in gene activation using the Sgs-4 locus of Drosophila melanogaster (1984) (13)
- A Distinct Type of Heterochromatin at the Telomeric Region of the Drosophila melanogaster Y Chromosome (2014) (12)
- Chapter 4 Immunofluorescent Analysis of Chroma Structure in Relation to Gene Activity: A Speculative Essay (1979) (12)
- Feature Points of View : Effective Partnerships Between K – 12 and Higher Education Building Successful Partnerships Between K – 12 and Universities (2005) (12)
- Chromatin structure at the 44D larval cuticle gene locus in Drosophila: the effect of a transposable element insertion. (1984) (12)
- Chromosome and expression mechanisms: a year dominated by histone modifications, transitory and remembered. (2002) (11)
- Distribution of chromosomal proteins in polytene chromosomes of Drosophila. (1991) (11)
- Cleavage reagents as probes of DNA sequence organization and chromatin structure: Drosophila melanogaster locus 67B1. (1983) (11)
- Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience † (2020) (10)
- Insensitivity of the present hsp26 chromatin structure to a TATA box mutation in Drosophila. (1994) (10)
- The proteins of polytene chromosomes of Drosophila hydei (2004) (9)
- Targeting of P-Element Reporters to Heterochromatic Domains by Transposable Element 1360 in Drosophila melanogaster (2015) (9)
- An immunofluorescent analysis of Drosophila polytene chromosomes with antisera directed against H3, H4, and a native H3-H4 complex. (1978) (8)
- Association of topoisomerase I with transcriptionally active loci in Drosophila. (1987) (8)
- G-OnRamp: a Galaxy-based platform for collaborative annotation of eukaryotic genomes (2019) (7)
- Heterochromatin: A Critical Part of the Genome (2014) (7)
- Targeting heterochromatin formation to transposable elements in Drosophila: Potential roles of the piRNA system (2013) (7)
- Production and characterization of antisera against three individual NHC proteins; a case of a generally distributed NHC protein (1978) (6)
- Role of chromatin structure in regulating gene expression: the hsp26 gene of Drosophila melanogaster. (1993) (6)
- Analysis of DNA structural patterns and sequence organization at the larval cuticle locus in Drosophila melanogaster (1983) (5)
- Chromosomes and expression mechanisms. (1997) (5)
- Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students. (2005) (5)
- Chromosomes and expression mechanisms: bringing together the roles of DNA, RNA and proteins. (2008) (4)
- Enforcing silencing: dynamic HP1 complexes in Neurospora (2012) (4)
- Immunofluorescent analysis of chromatin structure in relation to gene activity: a speculative essay. (1979) (4)
- Nonenzymatic cleavage of chromatin. (1989) (4)
- Stimulating conversations between HP1a and histone demethylase dKDM4A. (2008) (4)
- Chromatin structure of a P-element-transduced hsp-28 gene in Drosophila melanogaster (1986) (4)
- An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure (2017) (3)
- Pushing nucleosomes around. Chromatin. (1996) (3)
- G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation (2019) (3)
- A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene. (2001) (2)
- The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation (2019) (2)
- Undergraduate research in the Genomics Education Partnership: a comparative genomics project exploring genome organization and chromatin structure in Drosophila (2011) (2)
- Competencies: a cure for pre-med curriculum. (2011) (2)
- Building Back More Equitable STEM Education: Teach Science by Engaging Students in Doing Science (2021) (2)
- On the importance of taking a firm position. Chromatin structure and gene expression sponsored by Fundación Juan March, Madrid, Spain September 24-26, 1990. (1991) (2)
- Chromatin structure and gene expression in Drosophila. (1983) (2)
- Student Attitudes Contribute to the Effectiveness of a Genomics CURE (2022) (2)
- modENCODE and ENCODE resources for analysis of metazoan chromatin organization (2013) (2)
- A Hands-on Introduction to Hidden Markov Models (2016) (1)
- INCREASED NUCLEASE-SUSCEPTIBILITY OF ACTIVE CHROMATIN AT HEAT-SHOCK LOCI IN DROSOPHILA (1978) (1)
- G-OnRamp: A Galaxy-based platform for creating genome browsers for collaborative genome annotation (2018) (1)
- A high-mobility-group protein and its cDNAs from Drosophila melanogaster (1992) (1)
- Response to the Letter to the Editor by Dunning Hotopp and Klasson (2018) (1)
- The Impact of Genetic Background and Cell Lineage on the Level and Pattern of Position Effect Variegation (2019) (1)
- Isolation and distribution of a Drosophila protein preferentially associated with inactive regions of the genome (2004) (1)
- Title Comparative analysis of metazoan chromatin organization Permalink (2014) (0)
- DNase I hypersensitive sites in Drow ends of regions of transcription (chromatin structure/Drosophila melanogaster/heat shock) (2016) (0)
- Some Observations on DNA Structure and Chromatin Organization at Specific Loci in Drosophila melanogaster (1984) (0)
- Chromatin Structure and DNA Structure at the hsp 26 Locus of Drosophila (1988) (0)
- The Genomics Education Partnership: Exploring best practices in implementation of a genomics CURE (2020) (0)
- Chromatin structure related to gene expression in Drosophila (1989) (0)
- Chromatin Structure ofa P-Element-Transduced hsp-28 Genein (1986) (0)
- Correction: Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context (2014) (0)
- Promoting undergraduate research through the Genomics Education Partnership (2010) (0)
- G-OnRamp: Visualizing and Annotating Eukaryotic Genomes with Galaxy (2018) (0)
- The Genomics Education Partnership: Course‐based Research Experiences for Undergraduates (2018) (0)
- The Genomics Education Partnership: An Introduction to Bioinformatics in a Course-based Undergraduate Research Experience (CURE) (2017) (0)
- CHROMATIN STRUCTURE OF A SPECIFIC GENE IN ACTIVE AND INACTIVE STATES: A BRIEF REVIEW (1979) (0)
- Engaging biologists with big data using interactive genome annotation (2016) (0)
- Report from the ASCB Education Committee. (2002) (0)
- Heterochromatin and Eurochromatin—Organization, Packaging, and Gene Regulation (2004) (0)
- Marking time (2006) (0)
- Introduction of a maize heat-shock gene into the Drosophila genome by P-element mediated transformation (1985) (0)
- Chromosome Organization and Structure, Overview (2004) (0)
- G-OnRamp: Create UCSC assembly hubs and JBrowse/Apollo archives for collaborative eukaryotic genome annotations (2018) (0)
- Annotating Drosophila grimshawi Contig 15 By : (2012) (0)
- Genomics Education Alliance: Towards Genomics CURE templates (2020) (0)
- Microsoft Word-MendezMandtElginSecondSubmission (2013) (0)
- THE RELATIONSHIP OF CHROMATIN STRUCTURE TO DNA SEQUENCE ORGANIZATION AT A HEAT SHOCK LOCUS OF DROSOPHILA MELANOGASTER (1982) (0)
- WORKSHOP SUMMARY: Chromatin Structure (1982) (0)
- The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation (2019) (0)
- The Genomics Education Partnership: Introducing Undergraduates to Research by Engaging Them in Genome Annotation (2020) (0)
- Using genome browsers constructed by G-OnRamp to provide students with a Course-based Undergraduate Research Experience in genome annotation (2020) (0)
- A Bioinformatics Course‐based Undergraduate Research Experience (2015) (0)
- RNAi-dependent assembly of heterochromatin in Drosophila (2005) (0)
- Heterochromatic silencing in Drosophila melanogaster (2013) (0)
- Books received (1996) (0)
- Improving societies' harassment policies (2018) (0)
- Title A course-based research experience : How benefits change with increased investment in instructional time Permalink (2014) (0)
- Table of Contents (1984) (0)
- Introducing Genomics through Genome Annotation: Broadening Access to Course-Based Undergraduate Research Experiences (2018) (0)
- Nucleosome Repeat Structure Is Present in Chromosomes of Drosophila melanogaster Native Salivary (1982) (0)
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Sarah Elgin is affiliated with the following schools:
