Sarah Fortune
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American phthisiatrist
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Why Is Sarah Fortune Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sarah Merritt Fortune is an American Immunologist. She is a Full Professor of Immunology and Infectious Diseases in the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health.
Sarah Fortune's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues (2020) (1833)
- Definitions and guidelines for research on antibiotic persistence (2019) (575)
- Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput (2017) (426)
- Beyond binding: antibody effector functions in infectious diseases (2017) (424)
- A Functional Role for Antibodies in Tuberculosis (2016) (387)
- Mutually dependent secretion of proteins required for mycobacterial virulence. (2005) (387)
- Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection (2011) (386)
- Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug resistant tuberculosis (2013) (378)
- Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility (2012) (374)
- Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis (2017) (362)
- Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair (2009) (332)
- Heterogeneity in tuberculosis (2017) (315)
- Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform (2016) (288)
- Systematic Genetic Nomenclature for Type VII Secretion Systems (2009) (288)
- NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis (2009) (280)
- Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition (2009) (279)
- Sterilization of granulomas is common in both active and latent tuberculosis despite extensive within-host variability in bacterial killing (2013) (271)
- Ligation of CD40 on fibroblasts induces CD54 (ICAM‐1) and CD106 (VCAM‐1) up‐regulation and IL‐6 production and proliferation (1995) (255)
- Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization (2015) (243)
- Efferocytosis is an innate antibacterial mechanism. (2012) (230)
- Mycobacterium tuberculosis Inhibits Macrophage Responses to IFN-γ through Myeloid Differentiation Factor 88-Dependent and -Independent Mechanisms1 (2004) (220)
- Variation among Genome Sequences of H37Rv Strains of Mycobacterium tuberculosis from Multiple Laboratories (2010) (213)
- Seq-Well: A Portable, Low-Cost Platform for High-Throughput Single-Cell RNA-Seq of Low-Input Samples (2017) (184)
- Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape (2015) (179)
- Characterization of mycobacterial virulence genes through genetic interaction mapping. (2006) (173)
- Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection (2018) (165)
- A partner for the resuscitation‐promoting factors of Mycobacterium tuberculosis (2007) (156)
- Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria (2014) (153)
- Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection (2011) (152)
- Magnetic barcode assay for genetic detection of pathogens (2013) (149)
- IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure (2019) (142)
- Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis (2017) (138)
- DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis (2013) (124)
- Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance (2018) (100)
- Molecular Analysis of incHI1 Antimicrobial Resistance Plasmids from Salmonella Serovar Typhi Strains Associated with Typhoid Fever (2003) (99)
- Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria (2015) (97)
- EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity (2010) (96)
- Mycobacterium tuberculosis ESAT-6 Exhibits a Unique Membrane-interacting Activity That Is Not Found in Its Ortholog from Non-pathogenic Mycobacterium smegmatis* (2012) (96)
- The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome (2016) (92)
- PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis (2016) (86)
- Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells. (1995) (85)
- The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas (2017) (84)
- Mycobacterium tuberculosis--heterogeneity revealed through whole genome sequencing. (2012) (82)
- Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c (2014) (77)
- A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis (2016) (76)
- Erratum: Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput (2017) (67)
- TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities (2018) (64)
- Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages (2018) (60)
- DNA replication fidelity in Mycobacterium tuberculosis is mediated by an ancestral prokaryotic proofreader (2015) (60)
- Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response (2018) (56)
- Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques (2018) (54)
- Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. (2011) (53)
- Publisher Correction: Definitions and guidelines for research on antibiotic persistence (2019) (53)
- Protein Complexes and Proteolytic Activation of the Cell Wall Hydrolase RipA Regulate Septal Resolution in Mycobacteria (2013) (52)
- Cyclic-AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis (2012) (51)
- Bacterial Protein Secretion Is Required for Priming of CD8+ T Cells Specific for the Mycobacterium tuberculosis Antigen CFP10 (2008) (47)
- Rifampin Resistance Mutations Are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis* (2016) (46)
- The ESX System in Bacillus subtilis Mediates Protein Secretion (2014) (45)
- Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria (2018) (45)
- A bug’s life in the granuloma (2016) (42)
- The Psp system of Mycobacterium tuberculosis integrates envelope stress‐sensing and envelope‐preserving functions (2015) (42)
- Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis (2019) (41)
- Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control (2022) (37)
- Antibody Fc Glycosylation Discriminates Between Latent and Active Tuberculosis (2020) (33)
- Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis (2019) (33)
- Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response. (2019) (31)
- Polar assembly and scaffolding proteins of the virulence‐associated ESX‐1 secretory apparatus in mycobacteria (2012) (31)
- Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination (2011) (30)
- Robust IgM responses following intravenous vaccination with Bacille Calmette–Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques (2021) (30)
- The Spectrum of Drug Susceptibility in Mycobacteria. (2014) (30)
- Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. (2015) (27)
- Rifampicin and rifabutin resistance in 1000 Mycobacterium tuberculosis clinical isolates (2018) (26)
- SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis (2020) (26)
- Towards the use of breath for detecting mycobacterial infection: a case study in a murine model (2018) (24)
- The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection (2013) (22)
- TB biomarkers, TB correlates and human challenge models: New tools for improving assessment of new TB vaccines. (2016) (19)
- Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments (2020) (19)
- Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis (2020) (16)
- Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network (2018) (16)
- A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response (2020) (15)
- HIV Is Associated with Modified Humoral Immune Responses in the Setting of HIV/TB Coinfection (2020) (14)
- Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens. (2020) (14)
- Global Analysis of the Specificities and Targets of Endoribonucleases from Escherichia coli Toxin-Antitoxin Systems (2021) (13)
- A Mycobacterial Systems Resource for the Research Community (2021) (13)
- Requirement for Invariant Chain in Macrophages for Mycobacterium tuberculosis Replication and CD1d Antigen Presentation (2011) (12)
- Antibody Subclass and Glycosylation Shift Following Effective TB Treatment (2021) (11)
- Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor (2019) (11)
- Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control (2021) (11)
- Single-cell profiling of tuberculosis lung granulomas reveals functional lymphocyte signatures of bacterial control (2020) (9)
- RNA sequencing for transcript 5'-end mapping in mycobacteria. (2015) (9)
- RNA Extraction from a Mycobacterium under Ultrahigh Electric Field Intensity in a Microfluidic Device (2016) (9)
- Tuberculosis treatment failure associated with evolution of antibiotic resilience (2022) (9)
- Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments. (2020) (8)
- Dual RNAseq of human leprosy lesions identifies bacterial determinants linked to host immune response (2018) (8)
- DNA Replication Fidelity in the Mycobacterium tuberculosis Complex. (2017) (8)
- Spatiotemporal localization of proteins in mycobacteria (2021) (8)
- The surprising diversity of Mycobacterium tuberculosis: change you can believe in. (2012) (8)
- Biodiversity and hypervirulence of Listeria monocytogenes (2016) (8)
- CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A (2022) (8)
- The complex relationship between mycobacteria and macrophages: it's not all bliss. (2007) (8)
- The understanding of contact-dependent T-cell helper function in molecular, cellular and physiological detail. (1994) (7)
- Decoupling Directed and Passive Motion in Dynamic Systems: Particle Tracking Microrheology of Sputum (2013) (7)
- Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis (2022) (7)
- Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019. (2020) (6)
- JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia. (2022) (5)
- Mycobacterium tuberculosis e Heterogeneity revealed through whole genome sequencing (2012) (5)
- ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria (2020) (4)
- Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis (2021) (4)
- Multiplexed Strain Phenotyping Defines Consequences of Genetic Diversity in Mycobacterium tuberculosis for Infection and Vaccination Outcomes (2022) (3)
- Misunderstanding the goals of animal research (2018) (3)
- Cat scratch disease presenting as a breast mass. (2000) (3)
- Dividing oceans into pools: strategies for the global analysis of bacterial genes. (2006) (3)
- A Mycobacterium tuberculosis Specific IgG3 Signature of Recurrent Tuberculosis (2021) (3)
- Regulation of protein secretion by ... protein secretion? (2008) (3)
- Host transcription in active and latent tuberculosis (2010) (3)
- Robust IgM responses following vaccination are associated with prevention of Mycobacterium tuberculosis infection in macaques (2021) (2)
- High-Throughput CRISPR Screens To Dissect Macrophage-Shigella Interactions (2020) (2)
- Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure (2019) (2)
- Provisional identification of Haemophilus influenzae from sputum cultures within 1 h by rapid enzyme tests. (1991) (2)
- Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities (2019) (2)
- Fluorescence Imaging-Based Discovery of Membrane Domain-Associated Proteins in Mycobacterium smegmatis (2021) (2)
- Mycobacterium tuberculosis functional genetic diversity, altered drug sensitivity, and precision medicine (2022) (1)
- A tRNA-Acetylating Toxin and Detoxifying Enzyme in Mycobacterium tuberculosis (2021) (1)
- A FLOT1 host regulatory allele is associated with a recently expanded Mtb clade in patients with tuberculosis (2022) (1)
- A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages (2023) (1)
- Arginine methylation sites on SepIVA help balance elongation and septation in Mycobacterium smegmatis (2022) (1)
- Author response: A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis (2016) (1)
- Fc-engineered antibodies leverage neutrophils to drive control of Mycobacterium tuberculosis (2022) (1)
- Resistance to antimicorbial agents in Salmonella typhi in Vietnam: clinical response to therapy and molecular mechanisms (1998) (1)
- Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis (2019) (1)
- An N-of-1 Trial of Itacitinib for a Patient with Aplastic Anemia Associated with a Gain-of-Function Variant in STAT1 (2021) (1)
- GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling (2020) (0)
- Despite Vaccination T Cell Responses + Immunofocusing of CD8 Directs Mycobacterium tuberculosis (2010) (0)
- Comprehensive Essentiality Analysis of the <italic toggle='yes'>Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis (2017) (0)
- Affinity Reagents for Multiplexed, Rapid Diagnosis of Bacterial Infections at the Point of Care using Diagnostic Magnetic Resonance (2012) (0)
- Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance (2018) (0)
- Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs (2023) (0)
- Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis (2012) (0)
- IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure (2019) (0)
- Arginine methylation sites on SepIVA help balance elongation and septation of the cell wall in Mycobacterium smegmatis (2021) (0)
- The culprit behind celiac disease symptoms (2019) (0)
- A bug’s life in the granuloma (2015) (0)
- Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure (2019) (0)
- Recognition of the WXG Substrate YukE by the Type VII Secretion System in Bacillus subtilis (2013) (0)
- Asymmetry and aging of mycobacterial cells: a novel mechanism of diversification (2012) (0)
- High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes (2023) (0)
- Multivariate Analysis Establishes Airway T Cells as a Correlate of IV BCG-Mediated Protection Against Tuberculosis in Rhesus Macaques (2022) (0)
- POPULATION-LEVEL DRUG TOLERANCE THROUGH GROWTH ARREST AND METABOLIC REMODELING (2014) (0)
- Global analysis of the specificities and targets of endoribonucleases from E. coli toxin-antitoxin systems (2021) (0)
- Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP (2012) (0)
- Deciphering multicellular microenvironment of tuberculosis lung granulomas associated with bacterial control using high-throughput single-cell mRNA sequencing (2019) (0)
- New cell therapy fights brain tumors (2019) (0)
- Cell Network of Pattern Recognition Receptors within a Induces IL-12 p 70 via Synergistic Activation Transfer RNA Mycobacterium tuberculosis (2018) (0)
- Crystal structure of Rv3378c (2014) (0)
- Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis) (2022) (0)
- This Week in Science (2019) (0)
- Analysis of antiviral therapy in 241 cases with corona virus disease 2019 in Guangzhou (2020) (0)
- Illuminating host-mycobacterial interactions with functional genomic screening to inhibit mycobacterial pathogenesis (2020) (0)
- Early in vivo infection dynamics in non-human primates infected with Mycobacterium tuberculosis (MPF3P.813) (2014) (0)
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