Sarah Onuora
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Computer Science
Sarah Onuora's Degrees
- Masters Artificial Intelligence Stanford University
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)According to Wikipedia, Sarah Onuora is a Canadian rheumatologist and the chief editor of Nature Reviews Rheumatology. Education Onuora has a bachelor's degree in biology from McMaster University, Canada. Career In 2005 she worked in the editorial department of Rheumatology journal and she joined Nature Publishing in 2007, initially working on Nature Reviews Neurology before becoming a senior editor at Nature Reviews Rheumatology. She became the chief editor of Nature Reviews Rheumatology in 2015.
Sarah Onuora's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Osteoarthritis: Cartilage matrix stiffness regulates chondrocyte metabolism and OA pathogenesis (2015) (14)
- Osteoarthritis: Molecular imaging detects activated macrophages (2016) (13)
- Rheumatoid arthritis: Vagus nerve stimulation reduces RA severity in patients (2016) (12)
- Osteoarthritis: Targeting Rac1 via microparticle-based drug delivery system protects OA cartilage in vivo (2014) (10)
- Rheumatoid arthritis: Can tofacitinib be used as first-line monotherapy for RA? (2014) (9)
- Osteoarthritis: Sprifermin shows cartilage-protective effects in knee OA (2014) (8)
- Osteoarthritis: Wnt inhibitor shows potential as a DMOAD (2017) (8)
- Connective tissue diseases: Adipocyte–myofibroblast transition: linking intradermal fat loss to skin fibrosis in SSc (2015) (8)
- Novel cytokine, IL-41, linked with PsA (2019) (7)
- Experimental arthritis: Anti-TNF kills the macrophage response (2018) (7)
- Regenerative medicine: PBMCs stimulate chondrocyte migration and cartilage repair (2015) (7)
- Osteoarthritis: Metabolic syndrome and risk of knee OA (2017) (6)
- Osteoarthritis: Chondrocyte clock maintains cartilage tissue (2016) (6)
- Cytokines in disease: Genetic variation affects IL-6 response in synovial fibroblasts (2016) (6)
- Rheumatoid arthritis: Could glucose metabolism be a sweet target for RA therapy? (2016) (6)
- Rheumatoid arthritis: Sarilumab more effective than adalimumab (2017) (6)
- Rheumatoid arthritis: How bad is obesity for RA? (2012) (5)
- Somatic mutations cause VEXAS syndrome (2020) (5)
- Autoimmunity: IFNγ signals control germinal centre formation (2016) (5)
- Rheumatoid arthritis: RF levels predict RA risk in the general population (2012) (5)
- Rheumatoid arthritis: Anti-TNF agents go head-to-head (2017) (5)
- Therapy: Shot at sciatica relief misses the mark (2012) (5)
- Osteoarthritis: UCMA links cartilage and bone in OA (2017) (5)
- Autoimmunity: Human gut bacteria induce TH17 cells (2016) (4)
- Systemic lupus erythematosus: Epratuzumab not effective in phase III trials (2016) (4)
- Inflammation: Potassium channel regulates osteoclastogenesis (2018) (4)
- Vasculitis syndromes: Loss of immunoinhibitory checkpoint implicated in GCA (2017) (4)
- Positive results for anifrolumab in phase III SLE trial (2020) (4)
- Crystal arthritis: Canakinumab relieves gout flares when treatment options are limited (2012) (4)
- IL-37 linked to gout pathogenesis and treatment (2020) (4)
- Bone: Targeting myostatin could prevent bone destruction in inflammatory arthritis (2015) (4)
- Immunology: Hippo signalling influences T cell fate (2017) (4)
- Autoimmunity: Apoptotic cells induce immune memory (2016) (4)
- Therapy: Celecoxib reduces risk of ulcer bleeding (2017) (3)
- Pain: Granulocyte-macrophage colony-stimulating factor required for inflammatory and arthritic pain (2012) (3)
- Spondyloarthropathies: MIF drives inflammation and bone formation in AS (2017) (3)
- Gout: Short telomeres in gout linked with flares and CVD (2017) (3)
- Synovial fibroblast expansion in RA is driven by Notch signalling (2020) (3)
- New insights into RA genetics from GWAS meta-analysis (2021) (3)
- Autoinflammation: A new STING-associated monogenic autoinflammatory disease (2014) (3)
- ABCG2 SNP associated with early-onset gout (2020) (3)
- Connective tissue diseases: Epstein–Barr virus in Sjögren's syndrome salivary glands drives local autoimmunity (2014) (3)
- Rheumatoid arthritis: Adalimumab drives Treg cell expansion via membrane TNF (2016) (3)
- IL-36 inhibition to treat OA (2019) (3)
- Osteoimmunology: IgG immune complexes directly regulate bone homeostasis (2015) (3)
- Rheumatoid arthritis. How bad is obesity for RA? (2012) (3)
- Clinical trials: Glucosamine–chondroitin combo improves knee OA pain (2015) (3)
- Connective tissue diseases: A new therapeutic approach for APS? (2014) (3)
- Gut microbiome could predict drug response in RA (2021) (3)
- Abatacept no better than placebo for pSS (2020) (3)
- Autoimmunity: TFH cells link gut microbiota and arthritis (2016) (3)
- Experimental arthritis: JAK inhibition with tofacitinib curbs RANKL-induced joint damage (2012) (3)
- Namilumab improves RA symptoms (2019) (3)
- Bone research: Autophagy is central to joint destruction in arthritis (2012) (3)
- Rheumatoid arthritis: Novel NFκB inhibitor associated with RA severity (2015) (3)
- Targeting inflammation with collagen-binding antibodies (2019) (3)
- Inflammatory arthritis: Blood coagulation factor drives arthritis pathogenesis (2014) (3)
- Fibromyalgia: Optic nerve damaged in patients with fibromyalgia (2016) (3)
- Gene therapy counteracts bone loss in osteoporosis (2019) (3)
- Inflammation: Potent small molecule extinguishes the NLRP3 inflammasome (2015) (3)
- Rheumatoid arthritis: JAK-ing up inadequate RA therapy (2017) (2)
- Osteoarthritis: A role for CXCR2 signalling in cartilage homeostasis (2014) (2)
- Sprifermin benefits maintained at 5 years (2021) (2)
- First EULAR recommendations for Sjögren syndrome published (2019) (2)
- NSAIDs not linked to worse COVID-19 outcomes (2021) (2)
- Osteoarthritis: Arthroscopy does not delay TKA for knee OA (2018) (2)
- Burden of musculoskeletal diseases increasing (2019) (2)
- Therapy: Cell-type-specific approach to TNF inhibition (2016) (2)
- Rheumatoid arthritis: Clues to the HLA–RA connection from T-cell crossreactivity to vinculin and microorganisms (2015) (2)
- Connective tissue diseases: Blood vessel microenvironment sustains cell renewal in Dupuytren contracture nodules (2015) (2)
- Rare variants in SLE risk genes drive disease (2019) (2)
- Avacopan offers alternative to steroids for ANCA-associated vasculitis (2021) (2)
- Implanted ‘smart’ cells release biologic drugs on demand (2021) (2)
- Autoimmunity: DNASE1L3 prevents anti-DNA responses (2016) (2)
- New data emerging on outcomes for patients with COVID-19 and rheumatic diseases (2020) (2)
- Genetics: Subtype of JIA is genetically similar to adult RA (2018) (2)
- Erasing the memory of arthritis in joints (2021) (2)
- Targeting the CCR6–CCL20 axis improves experimental PsA (2021) (2)
- Rheumatoid arthritis: Local versus systemic treatment for tenosynovitis (2016) (2)
- Rheumatoid arthritis: SSAT1 inhibition slows synovial fibroblast invasion (2014) (2)
- Experimental arthritis: Antibody against CSF-1 receptor protects bone and cartilage (2014) (2)
- New positive results for upadacitinib in AS (2019) (2)
- Tofacitinib alleviates pain in RA, PsA and AS (2020) (2)
- Regenerative medicine: A nose for cartilage repair (2016) (2)
- Immunology: Metabolic changes modify Treg cell function (2016) (2)
- Osteoarthritis: Surgical options for hip OA: digging beneath the surface of implant survival (2012) (2)
- Osteoarthritis: Vitamin D not effective for knee OA (2016) (2)
- Rheumatoid arthritis: C5orf30 regulates severity of tissue destruction in RA (2015) (2)
- Systemic sclerosis: Antifibrotic effects of PDE4 blockade? (2017) (2)
- Systemic lupus erythematosus: Incidence of flare is increased in pregnancy (2018) (2)
- Apremilast reduces Behçet oral ulcers (2019) (1)
- Inflammation: Cytokines alter inflammatory responses via chromatin changes (2017) (1)
- Machine learning reveals antibody signature (2022) (1)
- JAK1 inhibitor superior to abatacept in head-to-head RA trial (2020) (1)
- Rheumatoid arthritis: Obesity skews markers of inflammation (2017) (1)
- Gut microbiome linked with OA knee pain (2019) (1)
- Hospitalization for infection on the rise in gout (2020) (1)
- DRESS linked to HLA alleles (2022) (1)
- Osteoarthritis: OA chondrocytes made senescent by genomic DNA damage (2012) (1)
- Comorbidities: Stroke risk increased after herpes zoster infection (2016) (1)
- Immunometabolism: IL-37 fights inflammation-induced fatigue (2017) (1)
- Osteoarthritis: Hydroxychloroquine no HERO for hand OA (2018) (1)
- Autoinflammation: Anakinra effective for resistant FMF in RCT (2017) (1)
- EULAR updates its RA management recommendations (2020) (1)
- Experimental arthritis: Inflammasome-driven arthritis: a new model of RA? (2014) (1)
- NEMO splice variant causes distinct autoinflammatory syndrome (2022) (1)
- Connective tissue diseases: Steroidal nano-drug suppresses murine lupus (2016) (1)
- Epigenetics: Demethylation of IFN-regulated genes in SLE neutrophils (2015) (1)
- Taking ABAT to OA (2019) (1)
- Cancer recurrence risk not increased by DMARDs (2021) (1)
- Myositis: Anti-NXP2 antibodies associated with severe JDM (2018) (1)
- Connective tissue diseases: A NET of peril for endothelial cells in SLE? (2014) (1)
- Regenerative medicine: Dishing up functional human cartilage (2014) (1)
- Vasculitis: New insights into risk factors for GPA (2018) (1)
- Therapy: Ustekinumab after anti-TNF failure: a step closer to the PSUMMIT of psoriatic arthritis therapy? (2014) (1)
- Clinical trials: Intravenous golimumab effective for PsA (2017) (1)
- Upadacitinib in MTX-naive RA (2020) (1)
- SLE risk variant regulates IRF8 expression (2022) (1)
- Rheumatoid arthritis: Methotrexate and bridging glucocorticoids in early RA (2014) (1)
- P. gingivalis exacerbates arthritis via gut barrier dysfunction (2019) (1)
- Synthetic Wnt agonists rapidly rebuild bone in vivo (2021) (1)
- Defibrotide inhibits NET-mediated thrombosis in APS models (2021) (1)
- Is Kawasaki disease a form of IgA vasculitis? (2019) (1)
- Treatment of pulmonary hypertension in SSc (2020) (1)
- Juvenile idiopathic arthritis: Evidence of gut-driven inflammation in new JIA (2017) (1)
- Spondyloarthritis: Evidence from animal studies supports the 'entheseal stress' hypothesis of ankylosing spondylitis (2012) (1)
- Rheumatoid arthritis: Higher disease risk in children of women with RA (2018) (1)
- Targeting adenosine in SSc (2020) (1)
- TNF inhibitors linked to septic arthritis (2023) (0)
- mTORC1 implicated in Still’s disease and MAS (2023) (0)
- Spondyloarthropathies: Tofacitinib shows promise in PsA trials (2017) (0)
- Tenascin C promotes pathological bone formation in AS (2021) (0)
- Pro-senescence therapy reduces joint inflammation (2020) (0)
- Lyme arthritis: Immune surveillance stops joint-invading Borrelia in mice (2014) (0)
- Inflammatory myopathies: Muscle pathology helps predict JDM outcomes (2016) (0)
- At-risk individuals willing to start interventions (2020) (0)
- Long-term response in RA apparent by 6 months (2019) (0)
- Multimorbidity worse in patients with RA (2020) (0)
- Adding belimumab improves lupus nephritis (2020) (0)
- Therapy: Biologics and risk of second malignant neoplasm (2018) (0)
- Targeting the IVD clock to halt degeneration (2022) (0)
- Ferritin-induced NETs lead to cytokine storm in AOSD (2023) (0)
- Vasculitis syndromes: Ultrasonography in GCA assessment (2017) (0)
- Anti-TNF therapy reverses gut dysbiosis in AS (2019) (0)
- Vasculitis syndromes: Efficacy of tocilizumab for GCA in RCT (2016) (0)
- Serum proteome altered in pre-RA (2020) (0)
- LDHD mutation leads to hyperuricaemia and gout (2019) (0)
- Stem cells: Does norepinephrine influence cartilage repair? (2014) (0)
- Electric scaffolds charge cartilage repair (2022) (0)
- GCA relapse common in ustekinumab trial (2020) (0)
- Antibodies induce fibromyalgia symptoms (2021) (0)
- Upadacitinib improves PsA in phase III trial (2021) (0)
- Inflammation: A new path to treating arthritis? (2013) (0)
- Targeting the CRP–HIF1α axis in RA improves response to leflunomide (2019) (0)
- Immunology: BiP peptides induce epitope-specific T-cell reactions in RA (2015) (0)
- Osteoarthritis: Joint resurfacing possibilities loom large (2016) (0)
- LLDAS is an attainable SLE treatment target (2019) (0)
- Flares not linked to ultrasound findings in JIA (2018) (0)
- RA remission maintained after MTX withdrawal (2020) (0)
- Denosumab shows promise for GIOP (2018) (0)
- Risankizumab improves PsA (2022) (0)
- Bimekizumab effective across the axSpA spectrum (2023) (0)
- Targeting pDCs in SSc (2021) (0)
- GWAS expands list of Sjögren syndrome risk loci (2022) (0)
- Complement activation precedes classifiable SLE (2019) (0)
- Engineered fusion protein disrupts CD40 signalling (2019) (0)
- Inflammation: Hit the DEK! (2017) (0)
- Risk factors: Oral contraceptive use linked to lower risk of RA (2017) (0)
- Intensive electroacupuncture reduces OA pain (2020) (0)
- Targeting IAPs ameliorates MPO-AAV (2022) (0)
- Obesity hampers effects of anti-TNF agents (2018) (0)
- New autoinflammatory disease caused by non-cleavable RIPK1 variants (2020) (0)
- Cell–cell interactions shape RA and PsA pathogenesis (2022) (0)
- Secukinumab might improve enthesitis in SpA (2021) (0)
- Neutrophils implicated in early enthesitis (2022) (0)
- Improving how we talk about gout (2019) (0)
- Abnormal gut transit linked to gastrointestinal symptoms in SSc (2020) (0)
- Omicron evades immunity from vaccines (2022) (0)
- Depression linked to seronegative RA risk (2020) (0)
- New OA risk factors and drug targets revealed (2021) (0)
- NETs implicated in COVID-19 in kids and adults (2022) (0)
- New treatments for amyloidosis (2021) (0)
- Knee OA progression risk with steroids or HA (2021) (0)
- Physical therapy better than steroids for knee OA (2020) (0)
- Treatment withdrawal is feasible in RA remission (2021) (0)
- Secukinumab effective for nr-axSpA (2020) (0)
- HCQ use not protective against SARS-CoV-2 (2020) (0)
- Target neutrophils to treat thrombotic APS? (2022) (0)
- Increased risk of infection-related death in SLE (2020) (0)
- MMF comparable to cyclophosphamide in AAV (2020) (0)
- Genetics: Meta-analysis reveals novel overlap in genetic aetiologies of paediatric autoimmune disorders (2015) (0)
- Rheumatoid arthritis: Does ultrasonography reliably detect bone erosion in RA metacarpophalangeal joints? (2012) (0)
- Connective tissue diseases: Risk of arterial events in patients with primary APS (2012) (0)
- Autoinflammatory diseases: TNF drives cryopyrinopathies in mice (2018) (0)
- Infection: Infection risk after switching biologics (2017) (0)
- Pharmacotherapy: Going upstream: peptidomimetics block shared-epitope signalling (2015) (0)
- Immunometabolism: Hyperactive macrophages link heart and joint disease (2018) (0)
- Rheumatoid arthritis: GO-FURTHER with intravenous golimumab for active RA (2012) (0)
- Febuxostat cardiovascular safety revisited (2020) (0)
- Cardiovascular risk underestimated in DISH (2020) (0)
- Stress triggers fibromyalgia-like pain in mice (2020) (0)
- TIGIT-Ig shows therapeutic potential in SLE (2019) (0)
- PLG nanoparticles target inflammatory monocytes in SSc (2022) (0)
- A new model to study BAFF-independent SLE (2019) (0)
- Anti-TNF dose can be reduced in PsA and axSpA (2021) (0)
- Repurposed drugs could target PIM kinases in early RA (2021) (0)
- Undiagnosed axSpA is prevalent in IBD (2022) (0)
- Daily atorvastatin safe for patients with RA (2019) (0)
- Pregnancy outcomes improving in axSpA (2023) (0)
- Antibody screening identifies FDRs at risk of RA (2020) (0)
- Non-invasive imaging reveals fibrotic activity in IgG4-RD (2020) (0)
- Osteoarthritis: Does metal-on-metal hip resurfacing confer a survival advantage over total hip replacement? (2014) (0)
- No benefit from adding MTX to ustekinumab (2023) (0)
- Inducing apoptosis in joint cells improves advanced arthritis (2021) (0)
- Guselkumab effective through 2 years in PsA trial (2021) (0)
- Tapering csDMARDs leads to more RA flares (2021) (0)
- Osteoarthritis: Resurfacing versus total hip arthroplasty for hip OA (2012) (0)
- Low-dose glucocorticoids benefit seniors with RA (2022) (0)
- TYK2 inhibition halts SpA (2020) (0)
- Fetuin-A peptide inhibits cartilage calcification (2023) (0)
- Autoantibodies disrupt muscle repair and promote IIM progression (2020) (0)
- Stratifying Sjögren syndrome into symptom-based subgroups (2019) (0)
- Inhibit tankyrase to preserve OA cartilage? (2019) (0)
- Therapies targeting FLS and TNF can have synergistic effects (2020) (0)
- Semaphorin 3G exacerbates joint inflammation (2022) (0)
- ‘Hyalinization’ for cartilage regeneration (2022) (0)
- Therapy. Shot at sciatica relief misses the mark. (2012) (0)
- Bone: Bare bones of glucocorticoid effects on metabolism (2012) (0)
- Long-term fatigue relief with secukinumab for AS (2020) (0)
- Single-cell RNA sequencing sheds light on cell-type specific gene expression in immune cells (2022) (0)
- Tildrakizumab shows promise in phase IIb study (2021) (0)
- Rheumatoid arthritis: Manipulating the FLS 'proteoglycan switch' could offer a new approach to RA therapy (2015) (0)
- Tanezumab improves difficult-to-treat OA (2020) (0)
- Properties of colour-coded DECT lesions vary (2020) (0)
- Pain: Caution needed in use of gabapentinoids for LBP (2017) (0)
- Paediatric rheumatic disease: Multi-pronged approach uncovers sJIA mechanisms (2017) (0)
- Annexin A1 could help prevent periprosthetic bone loss (2022) (0)
- Connective tissue diseases: Depleting plasmacytoid dendritic cells: a new therapeutic approach in SLE? (2014) (0)
- New insights into myositis genetics (2019) (0)
- New immunoassay to screen for RA (2023) (0)
- Vaccination guidance updated (2019) (0)
- Systemic lupus erythematosus: Trauma and PTSD linked with SLE risk (2017) (0)
- Sulf2 mediates the effects of TNF in RASFs (2022) (0)
- Biologic choice matters in PsA prevention (2023) (0)
- ETS1 implicated in polarization of tissue-destructive fibroblasts (2022) (0)
- Autoimmune disease increases CVD risk (2022) (0)
- Calprotectin tracks tocilizumab-treated RA (2022) (0)
- Rheumatoid arthritis: Risk from silica exposure influenced by smoking (2017) (0)
- CAR T cells induce remission in a patient with refractory SLE (2021) (0)
- Biopsy-driven trial a milestone towards precision medicine in RA (2021) (0)
- Rituximab shows potential for treatment of PMR (2021) (0)
- Autoimmunity: New insights into functional effects of the shared epitope (2013) (0)
- PR3 triggers granuloma formation in GPA (2023) (0)
- Freeing PDL1 alleviates autoimmunity (2022) (0)
- Fasinumab effective for chronic low back pain (2020) (0)
- Fibroblast A20 and its suppressor DREAM regulate fibrosis in SSc (2022) (0)
- Which NSAIDs are best for OA treatment? (2021) (0)
- Wearable devices track gout flares (2020) (0)
- Connective tissue diseases: Autoantibodies to PDGFR are profibrotic in vivo (2016) (0)
- Mitochondrial fumarate implicated in inflammation (2023) (0)
- Spondyloarthritis: Effects of certolizumab pegol sustained at 4 years (2018) (0)
- Single-cell-based platform maps response to candidate DMOADs (2022) (0)
- Draining OA from the synovium (2023) (0)
- VEXAS syndrome more common than originally thought? (2023) (0)
- Gene expression profiles in muscle differ in myositis subtypes (2020) (0)
- Pregnancy outcomes in SLE have not improved (2022) (0)
- Neuronal Fcγ receptors mediate joint pain in arthritis (2019) (0)
- Leflunomide plus glucocorticoids for IgG4-RD (2020) (0)
- Triple therapy boosts survival in catastrophic APS (2018) (0)
- Osteoclastogenic Treg cells promote bone loss in inflammatory arthritis (2021) (0)
- Use of platelet-rich plasma for knee OA not supported by RCT results (2022) (0)
- Experimental arthritis: Neutrophil microvesicles protect cartilage in arthritis (2016) (0)
- Rheumatoid arthritis: Long-term mavrilimumab safe and effective (2018) (0)
- Lyme arthritis: Spirochaete remnants could explain antibiotic-refractory Lyme arthritis (2012) (0)
- Paediatric rheumatic disease: Systemic JIA genetically distinct (2017) (0)
- Profiling comorbidities of inclusion body myositis (2021) (0)
- Proteins profile pre-symptomatic AAV (2023) (0)
- Spondyloarthritis: Reinforcing 'treat to target' for SpA (2017) (0)
- Systemic lupus erythematosus: Rituximab improves SLE disease activity (2018) (0)
- Lyme arthritis: Bystander-activated T cells contribute to Lyme arthritis (2018) (0)
- Acute inflammatory arthritis: Methotrexate for chronic chikungunya arthritis? (2018) (0)
- Immune cell profiles stratify AOSD endotypes (2022) (0)
- Autoimmunity: An evolving autoantibody response in RA? (2016) (0)
- Rheumatoid arthritis: Antidrug antibodies crossreact with biosimilars (2016) (0)
- Secukinumab reduces synovitis in PsA (2021) (0)
- Bone: Targeting epigenetic regulation of osteoclastogenesis to prevent bone loss (2015) (0)
- Antibiotics keep rheumatic heart disease at bay (2021) (0)
- Targeting UHRF1 in RA (2022) (0)
- SARS-CoV-2 vaccine safe for young patients (2022) (0)
- Rheumatoid arthritis: RA synovium harbours distinct fibroblast subsets (2018) (0)
- Plasma exchange fails to improve outcomes for ANCA-associated vasculitis (2020) (0)
- Short-term prednisolone improves hand OA (2019) (0)
- Anti-TNF response falls short in real-world cohort (2020) (0)
- Osteoarthritis: Arthroscopy does not delay TKA for knee OA. (2018) (0)
- Arthritis disease burden worse in children with Down syndrome (2020) (0)
- Early referral matters for RA outcomes (2020) (0)
- sCD13 role in arthritis mediated via bradykinin receptor (2022) (0)
- Connective tissue diseases: T cells in blood mark Sjögren syndrome activity (2018) (0)
- Vasculitis syndromes: PR3 on apoptotic cells promotes inflammation in GPA (2015) (0)
- Spondyloarthritis: Predictive factors of anti-TNF efficacy (2017) (0)
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Sarah Onuora is affiliated with the following schools:
