Satoshi Uematsu
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Computer Science
Satoshi Uematsu's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science Stanford University
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Satoshi Uematsu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pathogen Recognition and Innate Immunity (2006) (10861)
- Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses (2006) (3609)
- Toll-like receptors and innate immunity (2006) (2690)
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production (2008) (1656)
- Cell type-specific involvement of RIG-I in antiviral response. (2005) (1410)
- Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7 (2005) (1238)
- TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway (2003) (1133)
- Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4 (2002) (1107)
- Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 (2004) (1048)
- Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway (2005) (954)
- Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus (2005) (950)
- A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA (2006) (812)
- Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5 (2008) (765)
- Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin (2005) (666)
- TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines (2008) (641)
- Essential role of IPS-1 in innate immune responses against RNA viruses (2006) (522)
- Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction (2005) (476)
- Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells (2006) (465)
- Toll-like Receptors and Type I Interferons* (2007) (462)
- Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ (2004) (444)
- Deletion of TLR5 results in spontaneous colitis in mice. (2007) (436)
- Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease (2005) (432)
- Innate lymphoid cells regulate intestinal epithelial cell glycosylation (2014) (421)
- Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses1 (2002) (413)
- Activation and regulation of Toll-like receptors 2 and 1 in human leprosy (2003) (339)
- Differential Role of TLR- and RLR-Signaling in the Immune Responses to Influenza A Virus Infection and Vaccination (2007) (310)
- Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1* (2004) (297)
- Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum (2005) (289)
- Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling (2006) (287)
- Lipopolysaccharide-Dependent Prostaglandin E2 Production Is Regulated by the Glutathione-Dependent Prostaglandin E2 Synthase Gene Induced by the Toll-Like Receptor 4/MyD88/NF-IL6 Pathway1 (2002) (275)
- TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. (2008) (264)
- Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. (2004) (241)
- TLR Engagement Prevents Transplantation Tolerance (2006) (227)
- Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia (2010) (227)
- TLR Signaling Fine-Tunes Anti-Influenza B Cell Responses without Regulating Effector T Cell Responses1 (2007) (218)
- Toll-Like receptors (TLRs) and their ligands. (2008) (210)
- Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms. (2011) (206)
- Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice (2011) (202)
- TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen‐induced T cell activation (2006) (197)
- Cutting Edge: Tlr5−/− Mice Are More Susceptible to Escherichia coli Urinary Tract Infection1 (2007) (189)
- Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. (2010) (189)
- Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. (2011) (188)
- Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines (2008) (186)
- Pathological role of Toll-like receptor signaling in cerebral malaria. (2006) (176)
- MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV (2008) (176)
- Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. (2005) (176)
- Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor–mediated immune responses but not in TCR signaling (2007) (175)
- Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice. (2005) (166)
- Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β. (2013) (165)
- Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2 (2003) (163)
- A New Subset of CD103+CD8α+ Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity (2011) (154)
- Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-beta. (2005) (152)
- Role of Lipoteichoic Acid in the Phagocyte Response to Group B Streptococcus1 (2005) (147)
- Cutting Edge: Overlapping Functions of TLR7 and TLR9 for Innate Defense against a Herpesvirus Infection1 (2008) (143)
- Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury. (2006) (137)
- Regulation of Cytosolic Phospholipase A2 Activation and Cyclooxygenase 2 Expression in Macrophages by the β-Glucan Receptor* (2006) (136)
- Altered Inflammatory Responses in TLR5-Deficient Mice Infected with Legionella pneumophila1 (2007) (125)
- Evidence for Genes in Addition to Tlr7 in the Yaa Translocation Linked with Acceleration of Systemic Lupus Erythematosus1 (2008) (123)
- Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis (2009) (122)
- Toll-like receptors and innate immunity. (2006) (122)
- Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF-κB Signaling (2010) (121)
- Lymphoma Immunotherapy with CpG Oligodeoxynucleotides Requires TLR9 Either in the Host or in the Tumor Itself1 (2007) (120)
- Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists. (2010) (118)
- Epithelial glycosylation in gut homeostasis and inflammation (2016) (117)
- Papillomavirus-Like Particles Stimulate Murine Bone Marrow-Derived Dendritic Cells To Produce Alpha Interferon and Th1 Immune Responses via MyD88 (2004) (116)
- Membrane-Bound Prostaglandin E Synthase-1-Mediated Prostaglandin E2 Production by Osteoblast Plays a Critical Role in Lipopolysaccharide-Induced Bone Loss Associated with Inflammation (2006) (116)
- Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome (2014) (115)
- IL-6 and IL-10 Induction from Dendritic Cells in Response to Mycobacterium tuberculosis Is Predominantly Dependent on TLR2-Mediated Recognition1 (2004) (111)
- Increased Th17-inducing activity of CD14+ CD163 low myeloid cells in intestinal lamina propria of patients with Crohn's disease. (2013) (110)
- Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction (2008) (105)
- Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation1 (2005) (100)
- Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation. (2016) (94)
- Bacterial Endotoxin Induces the Release of High Mobility Group Box 1 via the IFN-β Signaling Pathway1 (2009) (94)
- Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling1 (2006) (92)
- Cutting Edge: Role of TANK-Binding Kinase 1 and Inducible IκB Kinase in IFN Responses against Viruses in Innate Immune Cells1 (2006) (92)
- Endotoxin and cisplatin synergistically induce renal dysfunction and cytokine production in mice. (2007) (90)
- Microglia‐specific expression of microsomal prostaglandin E2 synthase‐1 contributes to lipopolysaccharide‐induced prostaglandin E2 production (2005) (89)
- Plasmacytoid Dendritic Cells Promote Host Defense against Acute Pneumovirus Infection via the TLR7–MyD88-Dependent Signaling Pathway (2011) (88)
- CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Regulates Osteoblast Differentiation (2006) (88)
- Immune responses of TLR5+ lamina propria dendritic cells in enterobacterial infection (2009) (88)
- Direct Stimulation of tlr5+/+ CD11c+ Cells Is Necessary for the Adjuvant Activity of Flagellin1 (2009) (88)
- Toxoplasma gondii Genotype Determines MyD88-Dependent Signaling in Infected Macrophages1 (2006) (87)
- B Lymphocyte Activation by Human Papillomavirus-Like Particles Directly Induces Ig Class Switch Recombination via TLR4-MyD881 (2005) (87)
- TLR5 functions as an endocytic receptor to enhance flagellin‐specific adaptive immunity (2011) (84)
- Pivotal Advance: Toll‐like receptor regulation of scavenger receptor‐A‐mediated phagocytosis (2009) (81)
- Baculovirus Induces Type I Interferon Production through Toll-Like Receptor-Dependent and -Independent Pathways in a Cell-Type-Specific Manner (2009) (80)
- Induction of adaptive immunity by flagellin does not require robust activation of innate immunity (2009) (80)
- The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A. (2011) (75)
- Toll-Like Receptor 2 Mediates Apolipoprotein CIII–Induced Monocyte Activation: Retracted (2008) (74)
- A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids (2017) (74)
- TLR5-Deficient Mice Lack Basal Inflammatory and Metabolic Defects but Exhibit Impaired CD4 T Cell Responses to a Flagellated Pathogen (2011) (74)
- Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10 (2006) (73)
- Deficiencies of Myeloid Differentiation Factor 88, Toll-Like Receptor 2 (TLR2), or TLR4 Produce Specific Defects in Macrophage Cytokine Secretion Induced by Helicobacter pylori (2007) (73)
- Antibody-Antigen-Adjuvant Conjugates Enable Co-Delivery of Antigen and Adjuvant to Dendritic Cells in Cis but Only Have Partial Targeting Specificity (2012) (72)
- Systemic Flagellin Immunization Stimulates Mucosal CD103+ Dendritic Cells and Drives Foxp3+ Regulatory T Cell and IgA Responses in the Mesenteric Lymph Node (2012) (72)
- Identification of a TLR-Independent Pathway for Borrelia burgdorferi-Induced Expression of Matrix Metalloproteinases and Inflammatory Mediators through Binding to Integrin α3β11 (2006) (71)
- 'Toll' gates for future immunotherapy. (2006) (71)
- Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency (2007) (70)
- Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells. (2008) (70)
- Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis (2009) (69)
- Activation of smooth muscle and myenteric plexus cells of jejunum via toll‐like receptor 4 (2006) (69)
- TLR2-Dependent Inflammatory Response to Porphyromonas gingivalis Is MyD88 Independent, whereas MyD88 Is Required To Clear Infection (2009) (69)
- Flagellin enhances tumor-specific CD8⁺ T cell immune responses through TLR5 stimulation in a therapeutic cancer vaccine model. (2013) (68)
- Papillomavirus Capsid Mutation To Escape Dendritic Cell-Dependent Innate Immunity in Cervical Cancer (2005) (68)
- Nitrogen Dioxide Promotes Allergic Sensitization to Inhaled Antigen1 (2007) (66)
- MyD88 Deficiency Results in Tissue-Specific Changes in Cytokine Induction and Inflammation in Interleukin-18-Independent Mice Infected with Borrelia burgdorferi (2006) (65)
- Prostaglandin E2 Exerts Homeostatic Regulation of Pulmonary Vascular Remodeling in Allergic Airway Inflammation (2009) (64)
- Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice. (2013) (64)
- Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis (2012) (63)
- VP1686, a Vibrio Type III Secretion Protein, Induces Toll-like Receptor-independent Apoptosis in Macrophage through NF-κB Inhibition* (2006) (62)
- Pathways Regulating Cytosolic Phospholipase A2 Activation and Eicosanoid Production in Macrophages by Candida albicans* (2010) (61)
- Membrane-associated prostaglandin E synthase-1 is required for neuropathic pain (2004) (60)
- Toll-Like Receptor 5-Deficient Mice Have Dysregulated Intestinal Gene Expression and Nonspecific Resistance to Salmonella-Induced Typhoid-Like Disease (2008) (59)
- The C/EBPβ Isoform 34-kDa LAP Is Responsible for NF-IL-6-Mediated Gene Induction in Activated Macrophages, but Is Not Essential for Intracellular Bacteria Killing1 (2007) (57)
- Oral and intraperitoneal administration of phosphorothioate oligodeoxynucleotides leads to control of Cryptosporidium parvum infection in neonatal mice. (2006) (57)
- Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin (2009) (55)
- The role of Toll-like receptors in immune disorders (2006) (55)
- Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP (2013) (51)
- Receptor 4 / MyD 88 / NF-IL 6 Pathway Synthase Gene Induced by the Toll-Like 2 Glutathione-Dependent Prostaglandin E Production Is Regulated by the 2 E Lipopolysaccharide-Dependent Prostaglandin (2002) (49)
- Th2 allergic immune response to inhaled fungal antigens is modulated by TLR‐4‐independent bacterial products (2009) (47)
- Eosinophil depletion suppresses radiation-induced small intestinal fibrosis (2018) (45)
- Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. (2008) (44)
- Blocking of the TLR5 Activation Domain Hampers Protective Potential of Flagellin DNA Vaccine1 (2007) (44)
- Downstream Signals for MyD88-Mediated Phagocytosis of Borrelia burgdorferi Can Be Initiated by TRIF and Are Dependent on PI3K1 (2009) (43)
- Microsomal prostaglandin E synthase‐1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease‐like pathology in a mouse model (2013) (43)
- PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells. (2012) (42)
- Microsomal prostaglandin E synthase‐1 and cyclooxygenase‐2 are both required for ischaemic excitotoxicity (2010) (42)
- CD103−CD11b+ dendritic cells regulate the sensitivity of CD4 T cell responses to bacterial flagellin (2013) (41)
- G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2. (2017) (40)
- MyD88-Dependent Pathways Mediate Resistance to Cryptosporidium parvum Infection in Mice (2006) (39)
- Microsomal prostaglandin E synthase‐1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors (2010) (39)
- Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders. (2008) (39)
- Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice. (2018) (39)
- Toll-like receptor 3 enhances late-phase reaction of experimental allergic conjunctivitis. (2009) (38)
- Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum: CELL SIGNALING RECEPTORS, GPI STRUCTURAL REQUIREMENT, AND REGULATION OF GPI ACTIVITY (2004) (38)
- NFATc1 Mediates Toll-Like Receptor-Independent Innate Immune Responses during Trypanosoma cruzi Infection (2009) (37)
- Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts. (2020) (37)
- Leukemia Inhibitory Factor Coordinates the Down-regulation of the Visual Cycle in the Retina and Retinal-pigmented Epithelium* (2012) (36)
- Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors. Laboratory investigation. (2008) (36)
- Endothelial microsomal prostaglandin E synthase‐1 exacerbates neuronal loss induced by kainate (2010) (35)
- Commensal microbiota drive proliferation of conventional and Foxp3(+) regulatory CD4(+) T cells in mesenteric lymph nodes and Peyer's patches. (2013) (35)
- The innate immune system in the intestine (2010) (35)
- Airway epithelial indoleamine 2,3-dioxygenase inhibits CD4+ T cells during Aspergillus fumigatus antigen exposure. (2011) (34)
- Effects of long-term intake of a yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 on mice (2018) (33)
- Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis* (2015) (32)
- Colonic Patches Direct the Cross-Talk Between Systemic Compartments and Large Intestine Independently of Innate Immunity1 (2008) (32)
- Activation of Cytosolic Phospholipase A2α in Resident Peritoneal Macrophages by Listeria monocytogenes Involves Listeriolysin O and TLR2* (2008) (32)
- Escherichia coli verotoxin 1 mediates apoptosis in human HCT116 colon cancer cells by inducing overexpression of the GADD family of genes and S phase arrest (2005) (31)
- MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides polygyrus (2014) (30)
- Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes (2018) (30)
- Toll‐like receptor 6 drives interleukin‐17A expression during experimental hypersensitivity pneumonitis (2010) (29)
- Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis. (2017) (28)
- Functional Restoration of Bacteriomes and Viromes by Fecal Microbiota Transplantation. (2021) (28)
- Immunogenicity and protective efficacy offered by a ribosomal-based vaccine from Shigella flexneri 2a. (2007) (27)
- DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells (2018) (26)
- Microsomal prostaglandin E synthase-1 enhances bone cancer growth and bone cancer-related pain behaviors in mice. (2011) (25)
- Apolipoprotein CIII Induces Monocyte Chemoattractant Protein-1 and Interleukin 6 Expression Via Toll-Like Receptor 2 Pathway in Mouse Adipocytes: Retracted (2010) (25)
- Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers. (2010) (24)
- Endothelial microsomal prostaglandin E synthase-1 facilitates neurotoxicity by elevating astrocytic Ca2+ levels (2011) (24)
- Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production (2015) (23)
- Toll-Like Receptor 2 Deficiency Is Associated with Enhanced Severity of Group B Streptococcal Disease (2009) (23)
- Intestinal CD103+CD11b+ cDC2 Conventional Dendritic Cells Are Required for Primary CD4+ T and B Cell Responses to Soluble Flagellin (2018) (22)
- Gut carbohydrate inhibits GIP secretion via a microbiota/SCFA/FFAR3 pathway. (2018) (22)
- The inducible prostaglandin E synthase mPGES-1 regulates growth of endometrial tissues and angiogenesis in a mouse implantation model. (2011) (22)
- Critical Role of AZI2 in GM-CSF–Induced Dendritic Cell Differentiation (2013) (21)
- Antigen-specific Mucosal Immunity Regulates Development of Intestinal Bacteria-mediated Diseases. (2019) (21)
- Microarray analysis identifies apoptosis regulatory gene expression in HCT116 cells infected with thermostable direct hemolysin-deletion mutant of Vibrio parahaemolyticus. (2005) (21)
- Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy (2020) (21)
- Proton pump inhibitors enhance intestinal permeability via dysbiosis of gut microbiota under stressed conditions in mice (2020) (21)
- mPGES-1-expressing bone marrow-derived cells enhance tumor growth and angiogenesis in mice. (2010) (20)
- Alcohol abrogates human norovirus infectivity in a pH-dependent manner (2020) (20)
- [Toll-like receptor and innate immunity]. (2007) (20)
- Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC (2014) (19)
- IL‐3 is an important differentiation factor for the development of prostaglandin E2‐producing macrophages between C57BL/6 and BALB/c mice (2007) (19)
- Microsomal prostaglandin E synthase-1 promotes lung metastasis via SDF-1/CXCR4-mediated recruitment of CD11b+Gr1+MDSCs from bone marrow. (2019) (19)
- Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9 (2014) (18)
- Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells (2009) (16)
- Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1+CXCR5−/dim B-helper T cell induction (2017) (15)
- Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota (2020) (15)
- Deletion of microsomal prostaglandin E synthase-1 protects neuronal cells from cytotoxic effects of β-amyloid peptide fragment 31-35. (2012) (15)
- Prostaglandin E2 is critical for the development of niacin-deficiency-induced photosensitivity via ROS production (2013) (15)
- Microsomal prostaglandin E synthase-1 aggravates inflammation and demyelination in a mouse model of multiple sclerosis (2013) (15)
- Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson's disease (2019) (14)
- Oral MucoRice-CTB vaccine for safety and microbiota-dependent immunogenicity in humans: a phase 1 randomised trial. (2021) (14)
- PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation. (2009) (14)
- p53 Is a Host Cell Regulator during Herpes Simplex Encephalitis (2016) (13)
- Bacterial sphingophospholipids containing non-hydroxy fatty acid activate murine macrophages via Toll-like receptor 4 and stimulate bacterial clearance. (2013) (13)
- Roles of mPGES-1, an inducible prostaglandin E synthase, in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model. (2015) (13)
- Antigen-Specific T-Cell Responses to a Recombinant Fowlpox Virus Are Dependent on MyD88 and Interleukin-18 and Independent of Toll-Like Receptor 7 (TLR7)- and TLR9-Mediated Innate Immune Recognition (2011) (13)
- Human Papillomavirus Type-16 Virus-Like Particles Activate Complementary Defense Responses in Key Dendritic Cell Subpopulations1 (2004) (13)
- 5-Azacytidine-induced Protein 2 (AZI2) Regulates Bone Mass by Fine-tuning Osteoclast Survival* (2015) (12)
- High-fat diet-mediated dysbiosis exacerbates NSAID-induced small intestinal damage through the induction of interleukin-17A (2019) (12)
- Dysbiotic Fecal Microbiome in HIV-1 Infected Individuals in Ghana (2021) (11)
- Corrigendum: Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease (2005) (11)
- Role of Microsomal Prostaglandin E Synthase-1 (mPGES1)-Derived PGE2 in Patency of the Ductus Arteriosus in the Mouse (2008) (10)
- The protective role of TLR 6 in a mouse model of asthma is mediated by IL-23 and IL-17 A (2011) (9)
- Mucosal Mesenchymal Cells: Secondary Barrier and Peripheral Educator for the Gut Immune System (2017) (9)
- Interleukin (IL)-33 is dispensable for Schistosoma mansoni worm maturation and the maintenance of egg-induced pathology in intestines of infected mice (2020) (9)
- Critical role of microsomal prostaglandin E synthase-1 in the hydronephrosis caused by lactational exposure to dioxin in mice. (2012) (9)
- Therapeutic targeting of Toll-like receptors (2004) (9)
- PRRs in pathogen recognition (2006) (9)
- [Innate immunity and toll-like receptor]. (2006) (8)
- Generation of tumor antigen-specific murine CD8+ T cells with enhanced anti-tumor activity via highly efficient CRISPR/Cas9 genome editing (2018) (8)
- DNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-Adjuvant (2013) (8)
- Erratum: A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA (2006) (8)
- Erratum: Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway (2005) (7)
- Synthase Gene Induced by the Toll-Like Receptor 4/MyD88/ NF-IL6 Pathway (2002) (7)
- [TLR family and viral infection]. (2004) (7)
- Deficiencies of Myeloid differentiation factor 88, Toll-like receptor (TLR)-2, or 1 TLR4 produce specific defects in macrophage cytokine secretion induced by 2 (2007) (6)
- Development of prime-boost-type next-generation mucosal vaccines. (2019) (6)
- Identification of bacteriophage genome sequences with representation learning (2022) (5)
- Fecal microbiome composition in healthy adults in Ghana. (2020) (5)
- T Cell Responses without Regulating Effector TLR Signaling Fine-Tunes Anti-Influenza B (2007) (5)
- Abstract 5537: Toll-Like 2 Receptor Mediates Apolipoprotein CIII-Induced Monocyte Activation (2008) (5)
- Phage therapy for Clostridioides difficile infection (2022) (4)
- Abstract 10244: Apolipoprotein CIII Induces Monocyte Chemoattractant Protein-1 and Interleukin-6 Expression via Toll-Like Receptor 2 Pathway in Adipocytes in vitro and in vivo (2010) (4)
- Systemic Lupus Erythematosus Translocation Linked with Acceleration of Yaa in the Tlr7 Evidence for Genes in Addition to (2011) (3)
- Diet-Induced Obese Mice and Leptin-Deficient Lepob/ob Mice Exhibit Increased Circulating GIP Levels Produced by Different Mechanisms (2019) (3)
- Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer (2022) (3)
- Identification of a TLR-Independent Pathway (2006) (3)
- The microsomal prostaglandin E synthase-1/PGE2 axis induces recovery from ischemia via recruitment of regulatory T cells. (2022) (2)
- Multiplicative computation in a visual neuron sensitive to looming (2002) (2)
- Role of Adrenomedullin in Lyme Disease (2010) (2)
- Viral recognition and type I interferon production by Toll-like receptor and an RNA helicase, RIG-I (2005) (2)
- Role of interleukin-33 during Schistosoma mansoni infection (MPF7P.713) (2015) (2)
- Vaccine therapy for dysbiosis-related diseases (2020) (2)
- MyD88 signaling is not essential for induction of antigen‐specific B cell responses but is indispensable for protection against Pneumonia infection following oral vaccination with attenuated Salmonella expressing PspA antigen (2008) (2)
- PRAT 4 A-dependent expression of cell surface TLR 5 on neutrophils , classical monocytes and dendritic cells (2012) (2)
- Integrin Inflammatory Mediators through Binding to of Matrix Metalloproteinases and-Induced Expression Borrelia burgdorferi for Identification of a TLR-Independent Pathway (2006) (2)
- Ovariectomy-Induced Dysbiosis May Have a Minor Effect on Bone in Mice (2021) (2)
- [Role of toll-like receptor in immunological defence mechanism ]. (2005) (1)
- Isolation and Functional Analysis of Lamina Propria Dendritic Cells from the Mouse Small Intestine. (2016) (1)
- Interferon-α exerts proinflammatory properties in experimental radiation-induced esophagitis: Possible involvement of plasmacytoid dendritic cells. (2021) (1)
- Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle. (2022) (1)
- Recognition of Pathogens: Toll-Like Receptors (2008) (1)
- Needle- and Cold Chain- Free Rice-Based Oral Vaccine, MucoRice-CTB Shows Microbiota-Dependent Immunogenicity in Humans (2019) (1)
- Roles of an inducible prostaglandin E synthase, mPGES-1 in host in enhancement of tumor-associated angiogenesis (2011) (1)
- Characterization of the human gut virome in metabolic and autoimmune diseases (2022) (1)
- Geological characteristics of hydrothermal alteration zone landslides: Example from the Ikutahara-Minami landslide area, Hokkaido, Japan (2011) (1)
- StreptococcusResponse to Group B Role of Lipoteichoic Acid in the (2009) (0)
- Analysis of microsomal Prostaglandin E syntase-1(mPGEs-1)/PGE2 axis mechanism and relationship between regulatory T cells(Tregs) in promoting granulation formation. (2022) (0)
- DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells (2018) (0)
- Innate Immunity (2009) (0)
- Legionella pneumophila TLR 5-Deficient Mice Infected with Altered Inflammatory Responses in Smith and (2007) (0)
- [Innate immunity and tuberculosis]. (2008) (0)
- Interleukin (IL)-33 is dispensable for Schistosoma mansoni worm maturation and the maintenance of egg-induced pathology in intestines of infected mice (2021) (0)
- Heligmosomoides polygyrus Parasite to the Gastrointestinal Helminth MyD88 Signaling Inhibits Protective (2014) (0)
- Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes (2018) (0)
- Neutrophils Modulate Osteoblastic Niche for Hematopoietic Progenitors Via Prostaglandin E2 Production Triggered By Sympathetic Nervous System (2014) (0)
- TLR 2-Mediated Recognition Is Predominantly Dependent on tuberculosis Mycobacterium Cells in Response to IL-6 and IL-10 Induction from Dendritic (2004) (0)
- Interleukin (IL)-33 is dispensable for Schistosoma mansoni worm maturation, egg excretion, and the maintenance of egg-induced pathology in intestines of mice (2020) (0)
- Virus Infection and Vaccination in the Immune Responses to Influenza A Differential Role of TLR-and RLR-Signaling and Shizuo (2007) (0)
- Remodeling in Allergic Airway Inflammation Regulation of Pulmonary Vascular Exerts Homeostatic 2 Prostaglandin E (2009) (0)
- The protective role of TLR6 during experimental fungal asthma is mediated by IL-23 and IL-17A. (103.6) (2011) (0)
- Loss Associated with Inflammation Role in Lipopolysaccharide-Induced Bone Production by Osteoblast Plays a Critical 2 Synthase-1-Mediated Prostaglandin E Membrane-Bound Prostaglandin (2006) (0)
- mPGES-1 promotes granulation tissue angiogenesis through regulatory T-cell accumulation (2022) (0)
- Thymocyte TCR Signaling Cutting Edge: Pivotal Function of Ubc13 in (0)
- Response to Group B Streptococcus Role of Lipoteichoic Acid in the Phagocyte (2013) (0)
- TLR 4-MyD 88 Induces Ig Class Switch Recombination via Papillomavirus-Like Particles Directly B Lymphocyte Activation by Human and (2005) (0)
- Microsomal prostaglandin E synthase-1 induced by hemoglobin in microglia contributes to inflammation and neuronal death (2021) (0)
- Induction of microsomal prostaglandin E synthase-1 contributes to neuroinflammation and neurological dysfunctions in a mouse intracerebral hemorrhage model. (2020) (0)
- Mice Are More Susceptible to Escherichia coli Urinary Tract Infection (2007) (0)
- Induction of microsomal prostaglandin E synthase-1 contributes to dopaminergic neuronal death in rats and mice mesencephalic neuronal culture treated with 6-hydroxydopamine (2010) (0)
- Responses in Key Dendritic Cell Particles Activate Complementary Defense Human Papillomavirus Type-16 Virus-Like (2013) (0)
- Induction of mPGES-1 in dopaminergic neurons contributes to neurodegeneration in Parkinson's disease (2019) (0)
- Generation of tumor-specific CD8+ T-cells via highly efficient CRISPR/Cas9 genome editing (2017) (0)
- Janot et al. Eur J Immunol 2009 TLR5 and flagellin 3rd (2013) (0)
- Triggers Inflammatory Cytokine Responses Activation of Toll-Like Receptor 2 in Acne (2002) (0)
- Domain-Mediated NF-TLR / Nucleotide-Binding Oligomerization Inflammasome via Cytotoxins and Activate NLRP 3 Vibrio Pathogenic (2010) (0)
- Role of AZI 2 in osteoclastogenesis 1 5-azacytidine-induced protein 2 ( AZI 2 ) regulates bone mass by fine-tuning osteoclast survival (2015) (0)
- The role of microsomal Prostaglandin E syntase-1(mPGES-1)/PGE2 axis facilitates granulation tissueformation (2021) (0)
- Gut flora and inflammation (WS-067) Chairpersons: Hiroshi Ohno, Kenya Honda (2010) (0)
- Heligmosomoides polygyrus Parasite Immunity to the Gastrointestinal Helminth MyD88 Signaling Inhibits Protective (2014) (0)
- Identification of Bacteriophages Using Deep Representation Model with Pre-training (2021) (0)
- Flagellin Necessary for the Adjuvant Activity of Cells Is + CD 11 c + / + tlr 5 Direct Stimulation of Mizel (2009) (0)
- High-fat diet-mediated dysbiosis exacerbates NSAID-induced small intestinal damage through the induction of interleukin-17A (2019) (0)
- Intestine and Innate Immunity (2009) (0)
- Role of prostaglandin E2-EP2/EP4 signaling in the development of photosensitivity in pellagra (2013) (0)
- Toll-Like Receptor 2 Deficiency Is Associated with Enhanced Severity of Group B Streptococcal Disease (cid:1) (2009) (0)
- C/EBPβ controls mucosal fungal immunity through regulation of β-defensins (IRM11P.630) (2015) (0)
- Inflammatory cytokines and anti-microbial responses (PP-068) (2010) (0)
- Moduratory effect of Microsomal prostaglandin E synthase-1 on multiple sclerosis (2010) (0)
- Innate Immunity at Mucosal Surfaces (2020) (0)
- The Role of mPGES-1 in Promoting Granulation Tissue Angiogenesis Through Regulatory T-cell Accumulation (2022) (0)
- Role of Microsomal prostaglandin E synthase-1 in acute stress (2021) (0)
- AND REGULATION OF GPI ACTIVITY (GPI) STRUCTURAL REQUIREMENT, GLYCOSYLPHOSPHATIDYLINOSITOL SIGNALING RECEPTORS, : CELL Plasmodium falciparum Glycosylphosphatidylinositols of Macrophages by the Induction of Proinflammatory Responses in Mechanisms of Signal Transduction: (2013) (0)
- University of Intestinal CD103CD11b cDC2 Conventional Dendritic Cells Are Required for Primary CD4 T and B Cell Responses to Soluble Flagellin (2018) (0)
- Flagellated Pathogen Exhibit Impaired CD4 T Cell Responses to a Inflammatory and Metabolic Defects but TLR5-Deficient Mice Lack Basal (2011) (0)
- Killing Not Essential for Intracellular Bacteria Induction in Activated Macrophages , but Is Responsible for NF-IL-6-Mediated Gene Isoform 34-kDa LAP Is β The C / EBP (2007) (0)
- Microsomal Prostaglandin E Synthase-1 Deficiency Increases Dust Mite Antigen-Induced Airway Inflammation (2007) (0)
- Herpesvirus Infection a TLR7 and TLR9 for Innate Defense against Cutting Edge: Overlapping Functions of (2008) (0)
- Impact of neoadjuvant therapy on gut microbiome in patients with resectable/borderline resectable pancreatic ductal adenocarcinoma. (2023) (0)
- Induction of adaptive immunity by flagellin does not require TLR5 or robust innate immune activation (2008) (0)
- [TLR5+ DC-mediated immune response to bacterial infection in the intestine]. (2009) (0)
- Pathway MyD88-Dependent Signaling - via the TLR7 Defense against Acute Pneumovirus Infection Plasmacytoid Dendritic Cells Promote Host (2011) (0)
- in the Host or in the Tumor Itself Either Oligodeoxynucleotides Requires TLR9 Lymphoma Immunotherapy with CpG (2007) (0)
- PI 3 K Initiated by TRIF and Are Dependent on Can Be Borrelia burgdorferi Phagocytosis of Downstream Signals for MyD 88-Mediated (2009) (0)
- Fabrication of 4-6inch GaN free-standing substrates by VAS-method (2017) (0)
- DNA Vaccine Hampers Protective Potential of Flagellin Blocking of the TLR5 Activation Domain (2007) (0)
- High Mobility Group Box 1 via the IFN-Bacterial Endotoxin Induces the Release of (2009) (0)
- Streptococcus Response to Group B Role of Lipoteichoic Acid in the Phagocyte (2005) (0)
- Role of microsomal prostaglandin E synthase-1 in hippocampal inflammation after repetitive febrile seizures in mouse pups (2022) (0)
- Detection of slip surface in earth slide based on mineral assemblages -An example of hydrothermal alteration zone landslide in East Hokkaido Japan- (2014) (0)
- Responses in the Mesenteric Lymph Node Regulatory T Cell and IgA + Foxp3 Dendritic Cells and Drives + Mucosal CD103 Systemic Flagellin Immunization Stimulates (2012) (0)
- Eosinophil depletion is a potential therapeutic strategy for radiation-induced fibrosis in the small intestine (2018) (0)
- lung injury induced by hypoxia and LPS Adrenomedullin expression in a rat model of acute (2011) (0)
- Improvement of Automatic Generation Method of the Reply Sentence by Inductive Learning Using Common Portions on E-mail (2002) (0)
- University of Birmingham Intestinal CD103CD11b cDC2 Conventional Dendritic Cells Are Required for Primary CD4 T and B Cell Responses to Soluble Flagellin (2018) (0)
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What Schools Are Affiliated With Satoshi Uematsu?
Satoshi Uematsu is affiliated with the following schools: