Scott D. Emr
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American biologist
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Scott D. Emrbiology Degrees
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Cell Biology
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#209
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Biology
Scott D. Emr's Degrees
- PhD Biochemistry Stanford University
- Bachelors Biology University of California, San Diego
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Why Is Scott D. Emr Influential?
(Suggest an Edit or Addition)According to Wikipedia, Scott D. Emr is an American cell biologist and the founding and current Director of the Weill Institute for Cell and Molecular Biology at Cornell University, where he is also a Frank H.T. Rhodes Class of 1956 Professor at the Department of Molecular Biology and Genetics.
Scott D. Emr's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Autophagy as a regulated pathway of cellular degradation. (2000) (3473)
- Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I (2001) (1358)
- A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast (1995) (1341)
- Receptor downregulation and multivesicular-body sorting (2002) (1265)
- A unified nomenclature for yeast autophagy-related genes. (2003) (1235)
- The ESCRT pathway. (2011) (1164)
- Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases (1988) (982)
- Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. (1993) (912)
- Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. (2002) (846)
- Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum (1994) (813)
- The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function (1998) (771)
- Phosphoinositides as Regulators in Membrane Traffic (1996) (731)
- The fungal vacuole: composition, function, and biogenesis. (1990) (719)
- A Membrane Coat Complex Essential for Endosome-to-Golgi Retrograde Transport in Yeast (1998) (689)
- Fab1p PtdIns(3)P 5-Kinase Function Essential for Protein Sorting in the Multivesicular Body (1998) (645)
- Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. (2002) (626)
- The ESCRT complexes: structure and mechanism of a membrane-trafficking network. (2006) (563)
- The role of phosphoinositides in membrane transport. (2001) (514)
- The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene (1994) (510)
- Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. (1998) (481)
- Vps27 recruits ESCRT machinery to endosomes during MVB sorting (2003) (468)
- Arrestin-Related Ubiquitin-Ligase Adaptors Regulate Endocytosis and Protein Turnover at the Cell Surface (2008) (466)
- ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. (2012) (445)
- Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae (1990) (441)
- New Component of the Vacuolar Class C-Vps Complex Couples Nucleotide Exchange on the Ypt7 Gtpase to Snare-Dependent Docking and Fusion (2000) (439)
- Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis (2002) (436)
- Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites (2011) (423)
- Endosome to Golgi Retrieval of the Vacuolar Protein Sorting Receptor, Vps10p, Requires the Function of the VPS29, VPS30, and VPS35 Gene Products (1997) (418)
- Mammalian Tumor Susceptibility Gene 101 (TSG101) and the Yeast Homologue, Vps23p, Both Function in Late Endosomal Trafficking (2000) (417)
- The AP-3 Adaptor Complex Is Essential for Cargo-Selective Transport to the Yeast Vacuole (1997) (414)
- Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting (1988) (403)
- Endosomal transport function in yeast requires a novel AAA‐type ATPase, Vps4p (1997) (401)
- Fab1p Is Essential for PtdIns(3)P 5-Kinase Activity and the Maintenance of Vacuolar Size and Membrane Homeostasis (1998) (397)
- The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex (1989) (366)
- Isolation of yeast mutants defective in protein targeting to the vacuole. (1986) (365)
- Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes (2001) (363)
- Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. (2000) (358)
- Phosphoinositide signaling and the regulation of membrane trafficking in yeast. (2000) (353)
- A Multispecificity Syntaxin Homologue, Vam3p, Essential for Autophagic and Biosynthetic Protein Transport to the Vacuole (1997) (353)
- Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. (2004) (351)
- Molecular mechanisms of the membrane sculpting ESCRT pathway. (2013) (348)
- A membrane‐associated complex containing the Vps15 protein kinase and the Vps34 PI 3‐kinase is essential for protein sorting to the yeast lysosome‐like vacuole. (1993) (336)
- Suppressor mutations that restore export of a protein with a defective signal sequence (1981) (330)
- Coming together to define membrane contact sites (2019) (320)
- A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. (1997) (312)
- Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. (1989) (312)
- Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation. (2008) (303)
- Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. (2000) (302)
- Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4 (2007) (296)
- Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. (1996) (296)
- Ubiquitin and membrane protein turnover: from cradle to grave. (2012) (293)
- Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. (1996) (292)
- Functional Reconstitution of ESCRT-III Assembly and Disassembly (2009) (287)
- Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. (1991) (286)
- ESCRTing proteins in the endocytic pathway. (2007) (281)
- Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells (1995) (278)
- Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. (2002) (273)
- Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. (1995) (272)
- Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast (1994) (272)
- Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast (1995) (271)
- Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information (1988) (265)
- Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease (1987) (265)
- Yeast epsins contain an essential N‐terminal ENTH domain, bind clathrin and are required for endocytosis (1999) (252)
- Phosphoinositide 3-Kinases and Their FYVE Domain-containing Effectors as Regulators of Vacuolar/Lysosomal Membrane Trafficking Pathways* (1999) (249)
- The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate. (2002) (245)
- Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. (1994) (244)
- Osmotic stress–induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p (2002) (244)
- Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. (2001) (242)
- Location, Location, Location: Membrane Targeting Directed by PX Domains (2001) (238)
- Ubiquitin interactions of NZF zinc fingers (2004) (235)
- Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase (2002) (230)
- A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15 (1996) (224)
- Pan1p, Yeast eps15, Functions as a Multivalent Adaptor That Coordinates Protein–Protein Interactions Essential for Endocytosis (1998) (224)
- ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes (2006) (223)
- Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. (2005) (222)
- The AP-3 complex: a coat of many colours. (1998) (222)
- A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. (1997) (220)
- Mechanisms of protein localization. (1983) (217)
- Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae (2003) (216)
- Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component (1997) (212)
- COPI-independent Anterograde Transport: Cargo-selective ER to Golgi Protein Transport in Yeast COPI Mutants (1997) (207)
- Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product (1988) (202)
- Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy* (2002) (201)
- TORC1 Regulates Endocytosis via Npr1-Mediated Phosphoinhibition of a Ubiquitin Ligase Adaptor (2011) (201)
- VPS21 encodes a rab5‐like GTP binding protein that is required for the sorting of yeast vacuolar proteins. (1994) (199)
- Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. (2003) (194)
- Vam7p, a SNAP-25-Like Molecule, and Vam3p, a Syntaxin Homolog, Function Together in Yeast Vacuolar Protein Trafficking (1998) (194)
- Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome (1999) (188)
- The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices (2012) (188)
- A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole (1991) (184)
- The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal (1986) (183)
- ER-PM connections: sites of information transfer and inter-organelle communication. (2013) (180)
- Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. (1995) (179)
- Functional Traits and Niche-Based Tree Community Assembly in an Amazonian Forest (2008) (179)
- AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain. (1994) (178)
- Protein traffic in the yeast endocytic and vacuolar protein sorting pathways. (1998) (173)
- Journeys through the Golgi—taking stock in a new era (2009) (171)
- Phosphatidylinositol 3-phosphate recognition by the FYVE domain. (1999) (168)
- The Class C Vps Complex Functions at Multiple Stages of the Vacuolar Transport Pathway (2001) (167)
- Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant (1991) (165)
- Structure of the ESCRT-II endosomal trafficking complex (2004) (162)
- Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. (2002) (161)
- Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles. (1994) (160)
- Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. (2003) (159)
- The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. (1995) (159)
- A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast. (1997) (158)
- Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment (1993) (156)
- Endosomal localization and function of sorting nexin 1 (2002) (153)
- ESCRT‐II coordinates the assembly of ESCRT‐III filaments for cargo sorting and multivesicular body vesicle formation (2010) (151)
- Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein (1980) (145)
- Acidic Di-leucine Motif Essential for AP-3–dependent Sorting and Restriction of the Functional Specificity of the Vam3p Vacuolar t-SNARE (1998) (145)
- The Phosphatidylinositol 4,5-Biphosphate and TORC2 Binding Proteins Slm1 and Slm2 Function in Sphingolipid Regulation (2006) (143)
- Genome‐wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton (2004) (141)
- Yeast Gga coat proteins function with clathrin in Golgi to endosome transport. (2001) (140)
- Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3 (2008) (134)
- Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. (2008) (133)
- ARF is required for maintenance of yeast Golgi and endosome structure and function. (1998) (133)
- Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme (1985) (133)
- Formation of AP-3 transport intermediates requires Vps41 function (1999) (131)
- An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. (1983) (130)
- MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. (1999) (128)
- Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate. (2007) (126)
- A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development (1995) (126)
- Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. (2004) (126)
- Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis. (1990) (122)
- Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery (2008) (121)
- In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae (1992) (120)
- The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress (2013) (118)
- GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae (1986) (117)
- Regulation of PI4,5P2 synthesis by nuclear–cytoplasmic shuttling of the Mss4 lipid kinase (2003) (115)
- Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage λ receptor* (1980) (115)
- Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway. (1993) (112)
- Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase. (2008) (112)
- Mdm1/Snx13 is a novel ER–endolysosomal interorganelle tethering protein (2015) (112)
- Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting. (2007) (112)
- Importance of secondary structure in the signal sequence for protein secretion. (1983) (111)
- Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking (2007) (110)
- Eisosome proteins assemble into a membrane scaffold (2011) (106)
- The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast. (1993) (106)
- Localization and processing of outer membrane and periplasmic proteins in Escherichia coli strains harboring export-specific suppressor mutations. (1982) (103)
- A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery (1982) (102)
- A mechanism of protein localization: the signal hypothesis and bacteria (1980) (102)
- Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments (2015) (100)
- COPI in ER/Golgi and intra-Golgi transport: do yeast COPI mutants point the way? (1998) (99)
- A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery. (1991) (97)
- Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation. (1990) (97)
- Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. (1992) (97)
- Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy (2002) (96)
- Protein transport to the yeast vacuole. (1995) (96)
- Structural and Functional Organization of the ESCRT-I Trafficking Complex (2006) (96)
- Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling (2010) (96)
- The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology. (2005) (95)
- ESCRTs and human disease. (2009) (93)
- Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae (1994) (92)
- Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast. (1997) (91)
- Disruption of three phosphatidylinositol-polyphosphate 5-phosphatase genes from Saccharomyces cerevisiae results in pleiotropic abnormalities of vacuole morphology, cell shape, and osmohomeostasis. (1997) (91)
- The Saccharomyces cerevisiae LSB6 Gene Encodes Phosphatidylinositol 4-Kinase Activity* (2002) (91)
- Vps41p function in the alkaline phosphatase pathway requires homo-oligomerization and interaction with AP-3 through two distinct domains. (2001) (90)
- D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport (1984) (90)
- Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function (2010) (89)
- A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins (1996) (87)
- A putative zinc finger protein, Saccharomyces cerevisiae Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient alpha-factor prohormone maturation (1991) (86)
- Molecular mechanisms of inter-organelle ER-PM contact sites. (2015) (86)
- The Phosphoinositide Phosphatase Sjl2 Is Recruited to Cortical Actin Patches in the Control of Vesicle Formation and Fission during Endocytosis (2005) (85)
- Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast. (2004) (84)
- Ubiquitin-dependent lysosomal membrane protein sorting and degradation. (2015) (84)
- Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology. (1995) (83)
- Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation (2012) (81)
- A Novel RING Finger Protein, Vps8p, Functionally Interacts with the Small GTPase, Vps21p, to Facilitate Soluble Vacuolar Protein Localization* (1996) (81)
- Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein. (1978) (81)
- An essential role for a protein and lipid kinase complex in secretory protein sorting. (1992) (80)
- Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation. (2013) (78)
- Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae. (1999) (76)
- ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins (2017) (76)
- Heat‐shock proteins can substitute for SecB function during protein export in Escherichia coli. (1991) (74)
- Receptor signalling and the regulation of endocytic membrane transport. (1996) (74)
- A new class of lysosomal/vacuolar protein sorting signals. (1990) (70)
- Invertase beta-galactosidase hybrid proteins fail to be transported from the endoplasmic reticulum in Saccharomyces cerevisiae (1984) (67)
- ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis (2016) (65)
- Sequence and structural requirements of a mitochondrial protein import signal defined by saturation cassette mutagenesis (1989) (63)
- New component of ESCRT-I regulates endosomal sorting complex assembly (2006) (63)
- Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria. (1984) (63)
- Multiple Pathways for Vacuolar Sorting of Yeast Proteinase A (*) (1996) (60)
- Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex (2016) (60)
- In vitro reconstitution of intercompartmental protein transport to the yeast vacuole (1990) (57)
- Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1. (2011) (56)
- The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information (1987) (55)
- Novel pathways, membrane coats and PI kinase regulation in yeast lysosomal trafficking. (1998) (54)
- Molecular components of the signal sequence that function in the initiation of protein export (1982) (53)
- Cytoplasmic Inositol Hexakisphosphate Production Is Sufficient for Mediating the Gle1-mRNA Export Pathway* (2004) (53)
- Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins (2015) (53)
- Phosphoinositide kinase signaling controls ER-PM cross-talk (2016) (51)
- SnapShot: The ESCRT Machinery (2009) (49)
- Membrane protein recycling from the vacuole/lysosome membrane (2018) (46)
- Two novel WD40 domain–containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway (2011) (44)
- The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. (1993) (43)
- Invertase fusion proteins for analysis of protein trafficking in yeast. (2000) (41)
- Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis (2005) (40)
- The presence of both the signal sequence and a region of mature LamB protein is required for the interaction of LamB with the export factor SecB. (1990) (38)
- Genetic and biochemical studies of protein sorting to the yeast vacuole. (1993) (36)
- Rothman and Schekman SNAREd by Lasker for Trafficking (2002) (36)
- A Nobel Prize for membrane traffic: Vesicles find their journey’s end (2013) (35)
- Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. (1980) (33)
- The fungal vacuole: composition, function, and biogenesis (1990) (33)
- Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs (2017) (32)
- Sequence analysis of mutations that prevent export of lambda receptor, an Escherichia coli outer membrane protein. (1980) (30)
- Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System. (2021) (30)
- A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling (2019) (28)
- Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis (2011) (25)
- Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly (2019) (25)
- Characterization of a region in mature LamB protein that interacts with a component of the export machinery of Escherichia coli. (1990) (22)
- Rsp5 Ubiquitin ligase–mediated quality control system clears membrane proteins mistargeted to the vacuole membrane (2018) (21)
- PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway (2005) (21)
- Overview of Subcellular Fractionation Procedures for the Yeast Saccharomyces cerevisiae (2000) (19)
- The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P2 synthesis (2012) (18)
- Cell biology and physiology (2000) (18)
- Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. (1994) (17)
- Cargo sorting into multivesicular bodies in vitro (2009) (16)
- Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies. (2007) (15)
- Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching (2006) (15)
- Heterologous gene expression in yeast. (1990) (14)
- Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain (2019) (13)
- The Phosphatidylinositol 3,5-Bisphosphate (PI(3,5)P2)-dependent Tup1 Conversion (PIPTC) Regulates Metabolic Reprogramming from Glycolysis to Gluconeogenesis* (2013) (13)
- Novel protein kinase/phosphatidylinositol 3-kinase complex essential for receptor-mediated protein sorting to the vacuole in yeast. (1995) (13)
- Design principles of the ESCRT-III Vps24-Vps2 module (2020) (12)
- The genetics of protein secretion in Escherichia coli. (1981) (12)
- Genetic studies on mechanisms of protein localization in Escherichia coli K-12. (1980) (10)
- Protein sorting to the yeast vacuole (1996) (9)
- ESCRT-III and ER–PM contacts maintain lipid homeostasis (2020) (8)
- Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1 (2020) (8)
- The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites. (2021) (7)
- Regulation of PI 4 , 5 P 2 synthesis by nuclear ± cytoplasmic shuttling of the Mss 4 lipid kinase (6)
- Retrograde trafficking from the vacuole/lysosome membrane (2018) (6)
- Regulation of the Saccharomyces cerevisiae Vps34p phosphatidylinositol 3-kinase. (1997) (6)
- IMPORT OF ATP2-LacZ GENE FUSION PROTEINS INTO MITOCHONDRIA (1983) (6)
- Membranes and sorting. (1997) (6)
- Genetic and Biochemical Analyses of Yeast ESCRT. (2019) (5)
- Recruitment and organization of ESCRT-0 and ubiquitinated cargo via condensation (2021) (5)
- Mitochondrial protein import: isolation and characterization of the Saccharomyces cerevisiae MFT1 gene (1991) (5)
- A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling (2021) (5)
- Gene expression and protein purification (2000) (4)
- Mechanisms of protein localization (1983) (4)
- The Hob proteins are novel and conserved lipid binding proteins at ER-PM contact sites (2021) (4)
- Varshavsky's Contributions (2004) (4)
- Author response: Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments (2015) (3)
- ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and MVB vesicle formation (2009) (3)
- Golgi membrane protein Erd1 Is essential for recycling a subset of Golgi glycosyltransferases (2021) (3)
- The signal hypothesis in bacteria. (1982) (2)
- Structure of ESCRT-II endosomal trafficking complex (2004) (2)
- Genetic approaches to study export of LamB to the outer membrane. (1982) (2)
- The yeast Art1 arrestin domain contains disordered insertions that regulate its localization and activity (2019) (2)
- Compartmentalized transport, modification, and sorting of yeast vacuolar hydrolases. (1991) (1)
- Author response: ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins (2017) (1)
- An MFal-SUC 2 ( a-factor-invertase ) gene fusion for study of protein localization and gene expression in yeast ( recombinant DNA / transcriptional regulation / secretion / proteolytic processing / protein glycosylation ) (1999) (1)
- Methods for studying the regulation of membrane traffic by ubiquitin and the ESCRT pathway. (2019) (1)
- Slm2 Function in Sphingolipid Regulation and TORC2 Binding Proteins Slm1 and The Phosphatidylinositol 4,5-Biphosphate (2013) (1)
- Author response: The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress (2013) (1)
- FYVE Domains in Membrane Trafficking and Cell Signaling (2010) (1)
- X-Ray Diffraction data from Snf7 core (ESCRT-III filament), source of 5FD7 structure (2016) (0)
- Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis (1990) (0)
- - Vps15: Vacuolar protein sorting PK (S. cerevisiae) (1995) (0)
- 2 Angstrom X-ray structure of the yeast ESCRT-I Vps28 C-terminus (2007) (0)
- Transport and Secretion | Vacuoles (2021) (0)
- X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation A) (2015) (0)
- Author response: ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis (2016) (0)
- Vacuolar Protein Sorting in Yeast (1993) (0)
- 1 Adaptor linked K 63 di-Ubiquitin activates Nedd 4 / Rsp 5 E 3 ligase 1 2 (0)
- Characterization ofa Component oftheYeastSecretion Machinery: Identification oftheSEC18GeneProduct (1988) (0)
- Phosphoinositide Lipid Signaling in the Regulation of Membrane Trafficking and Organelle Identity (2007) (0)
- Mutations altering the cellular localization of the phage X receptor , an Escherichia coli outer membrane protein ( signal sequence / hybrid proteins / precursors / protein synthesis ) (0)
- Table of Contents (1993) (0)
- ESCRTing Receptor Down‐Regulation: Assembly and Function of the ESCRT‐III Complex (2013) (0)
- Immunoisolation of Endosomal Recycling Vesicles from Saccharomyces cerevisiae. (2022) (0)
- Genetic studies of yeast mitochondrial protein import (1985) (0)
- Faculty Opinions recommendation of GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network. (2004) (0)
- Information and peer review on the Internet (1997) (0)
- Table of Contents (1991) (0)
- Adaptor linked K63 di-ubiquitin activates Nedd4/Rsp5 E3 ligase (2021) (0)
- Characterization ofVPS34, a GeneRequired forVacuolar Protein Sorting andVacuole Segregation inSaccharomyces cerevisiaet (1990) (0)
- A Protein Kinase/Lipid Kinase Complex Required for Yeast Vacuolar Protein Sorting (1993) (0)
- 2 Angstrom X-ray structure of the yeast ESCRT-I Vps28 C-terminus in complex with the NZF-N domain from ESCRT-II (2007) (0)
- Ubiquitin Recognition by Npl4 Zinc-Fingers (2004) (0)
- Stractural insight into the interaction between ESCRT-III and Vps4 (2007) (0)
- Making connections: control of PI kinase signaling at ER‐PM junctions (351.3) (2014) (0)
- The 58 th Annual Meeting and Symposium of the Society of General Physiologists Lipid Signaling in Physiology (2005) (0)
- Structure of the MIT domain from a S. solfataricus Vps4-like ATPase (2007) (0)
- Protein-protein interactions and genomics (2000) (0)
- Coming together to define membrane contact sites (2019) (0)
- CHAPTER 152 – FYVE Domains in Membrane Trafficking and Cell Signaling (2003) (0)
- Author response: Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly (2019) (0)
- A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery: EMBO J. 10, 4049 (1992) (0)
- Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function (2010) (0)
- ESCRT-I core (2006) (0)
- X-Ray Diffraction data from Snf7 core (ESCRT-III filament), source of 5FD9 structure (2016) (0)
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Other Resources About Scott D. Emr
What Schools Are Affiliated With Scott D. Emr?
Scott D. Emr is affiliated with the following schools:
- University of California, Berkeley
- California Institute of Technology
- University of California, San Diego
- Vanderbilt University
- Carnegie Mellon University
- Stanford University
- Baylor College of Medicine
- Cornell University
- University of Iowa
- University of California, San Francisco
- Columbia University
- Harvard University
