Scott E. Kern
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Philosophy Biology
Scott E. Kern's Degrees
- Doctorate Medicine University of Pennsylvania
- PhD Biochemistry University of Pennsylvania
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(Suggest an Edit or Addition)Scott E. Kern's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genetic alterations during colorectal-tumor development. (1988) (5548)
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses (2008) (3758)
- DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 (1996) (2441)
- Definition of a consensus binding site for p53 (1992) (2053)
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis (2011) (1806)
- Identification of a chromosome 18q gene that is altered in colorectal cancers. (1990) (1771)
- Allelotype of colorectal carcinomas. (1989) (1362)
- Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma (1994) (1225)
- Pancreatic Intraepithelial Neoplasia: A New Nomenclature and Classification System for Pancreatic Duct Lesions (2001) (1096)
- Gene expression profiles in normal and cancer cells. (1997) (901)
- Progression model for pancreatic cancer. (2000) (874)
- Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene (2009) (788)
- DPC4 gene in various tumor types. (1996) (745)
- Tumor-suppressive pathways in pancreatic carcinoma. (1997) (729)
- Human Smad3 and Smad4 are sequence-specific transcription activators. (1998) (687)
- Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. (1997) (673)
- Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. (1996) (673)
- Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers (1996) (632)
- Scrambled exons (1991) (622)
- Prospective Risk of Pancreatic Cancer in Familial Pancreatic Cancer Kindreds (2004) (604)
- Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. (2000) (591)
- Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). (2001) (545)
- The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. (1998) (533)
- Oncogenic forms of p53 inhibit p53-regulated gene expression (1992) (505)
- p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. (1994) (491)
- Oncogenic forms of p53 inhibit p53-regulated gene expression. (1992) (477)
- Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. (2003) (466)
- p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma. (1997) (459)
- Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. (2002) (456)
- Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. (2003) (432)
- Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. (1999) (424)
- Genetic progression in the pancreatic ducts. (2000) (388)
- Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. (1994) (387)
- Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia. (2002) (368)
- Sodium boric acid: a Tris-free, cooler conductive medium for DNA electrophoresis. (2004) (351)
- Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication (1991) (346)
- Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression. (1998) (345)
- Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma. (2001) (332)
- Allelic Loss in Colorectal Carcinoma (1989) (331)
- Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer. (2001) (317)
- Discovery of novel tumor markers of pancreatic cancer using global gene expression technology. (2002) (312)
- Multifocal Neoplastic Precursor Lesions Associated With Lobular Atrophy of the Pancreas in Patients Having a Strong Family History of Pancreatic Cancer (2006) (308)
- Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas. (1998) (308)
- The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma. (2001) (303)
- Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation. (2000) (303)
- Homozygous deletion map at 18q21.1 in pancreatic cancer. (1996) (287)
- Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+. (1998) (266)
- Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity. (2000) (261)
- Fanconi anemia gene mutations in young-onset pancreatic cancer. (2003) (249)
- Focus on pancreas cancer. (2002) (247)
- Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas. (2000) (244)
- Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma–pancreatic carcinoma–prone families (2002) (241)
- Familial pancreatic cancer: a review. (1996) (240)
- BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets. (2003) (238)
- Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms. (1996) (234)
- Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]. (1989) (234)
- BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications. (2000) (228)
- Allelotype of pancreatic adenocarcinoma. (1994) (228)
- Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations. (2001) (226)
- Mad-related genes in the human (1996) (214)
- Colorectal neoplasia in juvenile polyposis or juvenile polyps. (1991) (209)
- A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. (2000) (202)
- Precursors to pancreatic cancer. (2007) (199)
- Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. (1998) (198)
- Genetics of pancreatic cancer. From genes to families. (1998) (193)
- Why your new cancer biomarker may never work: recurrent patterns and remarkable diversity in biomarker failures. (2012) (192)
- Nomenclature: Vertebrate Mediators of TGFβ Family Signals (1996) (189)
- Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion. (2002) (185)
- Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. (1998) (179)
- Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas. (1992) (175)
- Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression. (2002) (174)
- Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. (1998) (173)
- Molecular genetic profiles of colitis-associated neoplasms. (1994) (171)
- Microdissection and polymerase chain reaction amplification of genomic DNA from histological tissue sections. (1997) (166)
- History and principles of conductive media for standard DNA electrophoresis. (2004) (162)
- In vivo Therapeutic Responses Contingent on Fanconi Anemia/BRCA2 Status of the Tumor (2005) (161)
- K-ras mutation and pancreatic adenocarcinoma (1995) (155)
- Mutant p53 proteins bind DNA abnormally in vitro. (1991) (153)
- Dpc4 Protein in Mucinous Cystic Neoplasms of the Pancreas: Frequent Loss of Expression in Invasive Carcinomas Suggests a Role in Genetic Progression (2000) (147)
- Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic Cancer (2008) (144)
- p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. (1995) (142)
- ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma (2001) (140)
- Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias. (1995) (139)
- Invasion-specific genes in malignancy: serial analysis of gene expression comparisons of primary and passaged cancers. (2001) (136)
- Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. (2002) (132)
- Functional defects in the fanconi anemia pathway in pancreatic cancer cells. (2004) (130)
- The desmoplastic response to infiltrating breast carcinoma: gene expression at the site of primary invasion and implications for comparisons between tumor types. (2002) (130)
- A white paper: the product of a pancreas cancer think tank. (2001) (124)
- Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. (2003) (123)
- The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma. (1992) (122)
- Differing rates of loss of DPC4 expression and of p53 overexpression among carcinomas of the proximal and distal bile ducts (2001) (114)
- Identifying markers for pancreatic cancer by gene expression analysis. (1998) (112)
- Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion (2005) (111)
- Molecular pathology of pancreatic cancer. (2001) (110)
- Molecular pathogenesis of pancreatic cancer. (2006) (109)
- The fuzzy math of solid tumor stem cells: a perspective. (2007) (109)
- Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma. (1996) (100)
- Molecular pathogenesis of pancreatic cancer. (2006) (99)
- Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen. (1990) (97)
- Dpc4 transcriptional activation and dysfunction in cancer cells. (1998) (96)
- Molecular genetic basis of pancreatic adenocarcinoma (1999) (92)
- Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays. (2006) (88)
- Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers (2006) (87)
- G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation. (1999) (87)
- Transforming growth factor‐β responsiveness in DPC4/SMAD4‐null cancer cells (1999) (84)
- Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer (2005) (84)
- The Genetics of FANCC and FANCG in Familial Pancreatic Cancer (2004) (84)
- Pathology of incipient pancreatic cancer. (1999) (81)
- Progress in cancer genetics: lessons from pancreatic cancer. (1999) (81)
- Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression (2004) (80)
- A Phase I Clinical Trial of Lethally Irradiated Allogeneic Pancreatic Tumor Cells Transfected with the GM-CSF Gene for the Treatment of Pancreatic Adenocarcinoma. The Johns Hopkins Oncology Center, Baltimore, Maryland (1998) (79)
- Clinical importance of precursor lesions in the pancreas. (2007) (76)
- A syngeneic variance library for functional annotation of human variation: application to BRCA2. (2008) (75)
- Nomenclature: vertebrate mediators of TGFbeta family signals. (1996) (73)
- Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil: Is it time to move forward? (2008) (73)
- Large-Scale Allelotype of Pancreaticobiliary Carcinoma Provides Quantitative Estimates of Genome-Wide Allelic Loss (2004) (72)
- Ultra-fast high-resolution agarose electrophoresis of DNA and RNA using low-molarity conductive media. (2004) (71)
- MAP2K4/MKK4 Expression in Pancreatic Cancer (2004) (69)
- Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy (2005) (68)
- The relationship of quantitative nuclear morphology to molecular genetic alterations in the adenoma-carcinoma sequence of the large bowel. (1992) (68)
- Molecular genetics of exocrine pancreatic neoplasms. (1995) (66)
- Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies. (2000) (66)
- Genomic Sequencing of DPC4 in the Analysis of Familial Pancreatic Carcinoma (1997) (65)
- Role of the DPC4 Tumor Suppressor Gene in Adenocarcinoma of the Ampulla of Vater: Analysis of 140 Cases (2003) (65)
- Analysis of Anaphase Figures in Routine Histologic Sections Distinguishes Chromosomally Unstable from Chromosomally Stable Malignancies (2003) (65)
- Missense Mutations of MADH4 (2004) (63)
- Identification of 12p as a region of frequent deletion in advanced prostate cancer. (1998) (62)
- Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition (2005) (61)
- Molecular genetic alterations in ductal pancreatic adenocarcinomas. (2000) (60)
- Familial pancreatic cancer. (1999) (60)
- Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags (2004) (60)
- Mutation rate of MAP2K4/MKK4 in breast carcinoma (2002) (59)
- DPC4 gene mutation in colitis associated neoplasia. (1997) (58)
- Polymorphisms of SPINK1 N34S and CFTR in Patients with Sporadic and Familial Pancreatic Cancer (2003) (58)
- High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif. (2007) (56)
- Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options. (2006) (56)
- A phase I clinical trial of lethally irradiated allogeneic pancreatic tumor cells transfected with the GM-CSF gene for the treatment of pancreatic adenocarcinoma. (1998) (54)
- Direct demonstration in intestinal secretions of an IgA memory response to orally administered Shigella flexneri antigens. (1982) (53)
- An Introduction to Pancreatic Adenocarcinoma Genetics, Pathology and Therapy (2002) (52)
- Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss. (2006) (51)
- Pancreatic cancer. (2002) (49)
- Novel germline p16INK4 allele (Asp145Cys) in a family with multiple pancreatic carcinomas (1998) (49)
- Tumor-suppressor genes in pancreatic cancer. (1998) (49)
- Pancreaticobiliary cancers with deficient methylenetetrahydrofolate reductase genotypes. (2005) (48)
- Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers (2000) (48)
- Advances from genetic clues in pancreatic cancer (1998) (47)
- The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting (2011) (46)
- Reversal by antrectomy of endocrine cell hyperplasia in the gastric body in pernicious anemia: a morphometric study. (1990) (44)
- A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T (2003) (44)
- Emerging molecular biology of pancreatic cancer. (2008) (42)
- Genomic alterations in distal bile duct carcinoma by comparative genomic hybridization and karyotype analysis (1999) (42)
- SOS1 mutations are rare in human malignancies: Implications for Noonan syndrome patients (2008) (41)
- An integrated high-resolution physical map of the DPC/BRCA2 region at chromosome 13q12. (1995) (40)
- Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online. (1998) (39)
- Pancreatic intraepithelial neoplasia and infiltrating adenocarcinoma: analysis of progression and recurrence by DPC4 immunohistochemical labeling. (2001) (38)
- Radiolabeled Anti-Claudin 4 and Anti-Prostate Stem Cell Antigen: Initial Imaging in Experimental Models of Pancreatic Cancer (2007) (35)
- Stromal responses to carcinomas of the pancreas: Juxtatumoral gene expression conforms to the infiltrating pattern and not the biologic subtype (2005) (35)
- Genetic counseling and testing for germline p16 mutations in two pancreatic cancer-prone families. (2000) (35)
- Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy. (2006) (34)
- Targeting Fanconi Anemia/BRCA2 Pathway Defects in Cancer: The Significance of Preclinical Pharmacogenomic Models (2007) (33)
- Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX. (2005) (31)
- The structural basis of molecular genetic deletions. An integration of classical cytogenetic and molecular analyses in pancreatic adenocarcinoma. (1997) (31)
- Hereditary factors in pancreatic cancer. (2002) (31)
- Functional mapping of the MH1 DNA-binding domain of DPC4/SMAD4. (2000) (31)
- High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter (2002) (30)
- Functional Screen of the Fanconi Anemia Pathway in Cancer Cells by Fancd2 Immunoblot (2004) (29)
- High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter. (2003) (29)
- p53: tumor suppression through control of the cell cycle. (1994) (29)
- Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. (2009) (29)
- Structural Analysis of the Cancer-specific Promoter in Mesothelin and in Other Genes Overexpressed in Cancers* (2011) (29)
- FAM190A deficiency creates a cell division defect. (2013) (27)
- Cancer gets Mad: DPC4 and other TGFbeta pathway genes in human cancer. (1996) (27)
- Klenow co-sequencing: a method for eliminating "stops". (1994) (27)
- Nuclear localization of Dpc4 (Madh4, Smad4) in colorectal carcinomas and relation to mismatch repair/transforming growth factor-beta receptor defects. (2001) (27)
- Beverage-agarose gel electrophoresis: an inquiry-based laboratory exercise with virtual adaptation. (2006) (26)
- Molecular genetics and related developments in pancreatic cancer. (1999) (26)
- High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells (2001) (26)
- Analytic model for academic research productivity having factors, interactions and implications (2011) (26)
- High‐resolution deletion mapping of chromosome arm 1p in pancreatic cancer identifies a major consensus region at 1p35 (1999) (25)
- Elegance, silence and nonsense in the mutations literature for solid tumors (2006) (24)
- Stagnation and herd mentality in the biomedical sciences (2004) (23)
- Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells. (1999) (23)
- Loss of Expression of Dpc 4 in Pancreatic Intraepithelial Neoplasia : Evidence That DPC 4 Inactivation Occurs Late in Neoplastic Progression 1 (2000) (22)
- MKK4 status predicts survival after resection of gastric adenocarcinoma. (2006) (22)
- DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells (2013) (20)
- Improved DNA Electrophoresis in Conditions Favoring Polyborates and Lewis Acid Complexation (2010) (20)
- High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells. (2007) (19)
- Gene-specific selection against experimental fanconi anemia gene inactivation in human cancer (2007) (19)
- Distinguishing Rational from Irrational Applications of Pharmacogenetic Synergies from the Bench to Clinical Trials (2007) (19)
- Gastric antral vascular ectasia ("watermelon stomach"): radiologic findings. (1991) (18)
- Genomic FHIT analysis in RER+ and RER− adenocarcinomas of the pancreas (2000) (18)
- The genetics of ductal adenocarcinoma of the pancreas in the year 2020: dramatic progress, but far to go (2020) (17)
- Biological clues to potent DNA-damaging activities in food and flavoring. (2013) (17)
- Multiple-criterion evaluation of reported mutations: A proposed scoring system for the intragenic somatic mutation literature (2006) (16)
- Differential expression of multiple genes in association with MADH4/DPC4/SMAD4 inactivation in pancreatic cancer. (2008) (15)
- Treatment of familial pancreatic cancer and its precursors (2005) (15)
- Malignant fibrous histiocytoma of the heart presenting as unilateral pulmonary thromboembolism and infarct. (1985) (15)
- The Essential Similarity of TGFβ and Activin Receptor Transcriptional Responses in Cancer Cells (2003) (15)
- Copy‐number methods dramatically underestimate loss of heterozygosity in cancer (2006) (15)
- Targeted deletion of Smad 4 shows it is required for transforming growth factor b and activin signaling in colorectal cancer cells (1998) (13)
- FAM190A Rearrangements Provide a Multitude of Individualized Tumor Signatures and Neo-antigens in Cancer (2011) (13)
- Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: Considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers (2006) (13)
- A proposed clinical test for monitoring fluoropyrimidine therapy: Detection and stability of thymidylate synthase ternary complexes (2006) (13)
- Novel homozygous deletions of chromosomal band 18q22 in pancreatic adenocarcinoma identified by STS marker scanning (1999) (12)
- Whose Hypothesis? Ciphering, Sectorials, D Lesions, Freckles and the Operation of Stigler's Law (2002) (12)
- Frequent germline deletion polymorphism of chromosomal region 8p12-p21 identified as a recurrent homozygous deletion in human tumors. (2001) (12)
- Theoretical Proposal: Allele Dosage of MAP2K4/MKK4 Could Rationalize Frequent 17p Loss in Diverse Human Cancers (2006) (12)
- Use and benefits of a Web site for pancreatic cancer. (1998) (11)
- Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes. (2014) (11)
- LOCAL IgA‐MEMORY RESPONSE TO BACTERIAL ANTIGENS * (1983) (11)
- Adenocarcinoma of the pancreas: Factors influencing outcome after pancreaticoduodenectomy - The Johns Hopkins experience (1994) (10)
- A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing (2012) (9)
- INK4 genes in pancreatic carcinoma. (1996) (9)
- Analysis of Polymorphisms and Haplotype Structure of the Human Thymidylate Synthase Genetic Region: A Tool for Pharmacogenetic Studies (2012) (9)
- Tumor suppressive pathways in pancreatic cancer (1997) (8)
- Reexamining a proposal (2011) (8)
- Where's the passion? (2010) (8)
- Three cases of gastric spirochetelike organisms. (1989) (8)
- Are we systematically under-dosing patients with fluorouracil? (2015) (8)
- Molecular genetics of pancreatic carcinoma (1995) (8)
- Progression Model for Pancreatic Cancer 1 (2000) (8)
- Molecular genetics of ductal pancreatic neoplasia (2000) (8)
- MKK4 as oncogene or tumor supressor: In cancer and senescence, the story's getting old (2010) (8)
- Isolation of YAC insert sequences by representational difference analysis. (1995) (8)
- Molecular Genetics of Pancreatic Cancer (2008) (7)
- Bacterial overgrowth and mucosal changes in isolated (Thirty-Vella) ileal loops in rabbits. Effects of intraluminal antibiotics. (1987) (7)
- Nonspecific enhancement of gene expression by compounds identified in high-throughput cell-based screening. (2004) (7)
- Smoking and cervical cance: To the editor (1984) (6)
- Quantitative Selection Constants (2002) (6)
- Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. (2012) (6)
- Salivary α-amylase, serum albumin, and myoglobin protect against DNA-damaging activities of ingested dietary agents in vitro. (2014) (6)
- Inferential statistics, power estimates, and study design formalities continue to suppress biomedical innovation (2014) (5)
- Homozygous Deletion Map at 18 q 21 . 1 in Pancreatic Cancer 1 (2006) (5)
- Molecular genetics of pancreatic adenocarcinoma (1994) (5)
- p 53 Mutations in Pancreatic Carcinoma and Evidence of Common Involvement of Homocopolymer Tracts in DNA Microdeletions 1 (2006) (5)
- Oncogenic levels of mitogen‐activated protein kinase (MAPK) signaling of the dinucleotide KRAS2 mutations G12F and GG12‐13VC (2001) (5)
- Advances in Brief Detection of Mitochondrial DNA Mutations in Pancreatic Cancer Offers a “ Mass ”-ive Advantage over Detection of Nuclear DNA Mutations 1 (2001) (4)
- Larger organ size caused by obesity is a mechanism for higher cancer risk (2020) (4)
- Ancestral trees for modeling stem cell lineages genetically rather than functionally: understanding mutation accumulation and distinguishing the restrictive cancer stem cell propagation theory and the unrestricted cell propagation theory of human tumorigenesis. (2008) (4)
- Pancreatic cancer pathology viewed in the light of evolution (2021) (3)
- Targeting Fanconi Anemia / BRCA 2 Pathway Defects in Cancer : The Significance of Preclinical (2006) (3)
- A model for Paneth cell study: tissue culture of the hyperplastic Paneth cell population of rabbit Thiry-Vella ileal loops. (1987) (2)
- Molecular genetic alterations as potential prognostic indicators in colorectal carcinoma and molecular genetics of colorectal carcinoma (1993) (2)
- Microvascular Architecture in a Case of Gastric Antral Vascular Ectasia (Watermelon Stomach) (2014) (2)
- Dpc 4 Transcriptional Activation and Dysfunction in Cancer Cells 1 (2006) (2)
- Hybrids of aneuploid human cancer cells permit complementation of simple and complex cancer defects (2009) (2)
- Erratum: A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T (2005) (2)
- Genetic Pathways in Pancreatic Tumorigenesis (2008) (1)
- Investigational strategies for detection and intervention in early-stage pancreatic cancer (1994) (1)
- Corrigendum: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma (1994) (1)
- Genome Annotation by Shotgun Inactivation of a Native Gene in Hemizygous Cells: Application to BRCA2 with Implication of Hypomorphic Variants (2015) (1)
- Molecular biology of pancreas cancer (2015) (1)
- Fellowship Goals for Ph.D.'s and M.D.'s: A Primer on the Molecular Biology Postdoctoral Experience (2002) (1)
- Among pancreatic adenocarcinomas treated by whipple resection, an intact DPC4 portends a significantly improved patient survival (2001) (1)
- Hereditary Pancreatic Cancer: Part II. Candidate Genes (1997) (0)
- Correction. Smoking and cervical cancer. (1984) (0)
- Erratum: (BioTechniques (1994) 17 (286-288)) (1995) (0)
- Abstract 3580: Acetaldehyde and drug hypersensitivities of Fanconi anemia defects: Implications for cancer initiation, prevention, and therapy. (2013) (0)
- Representational Difference Analysis of Human Breast Cancer. (1998) (0)
- Hereditary Pancreatic Cancer: Part I. The Genetic Profile (1997) (0)
- Abstract LB-353: Development of thymidylate synthase ternary complex-specific antibody: A new way to tailor 5-fluorouracil dosing (2012) (0)
- Clinical and Pathological Associations with Molecular Genetic Alterations in Colorectal Carcinoma (1990) (0)
- Chapter 2 Molecular Genetics of Pancreatic Cancer (2018) (0)
- Tunable Diode Laser Spectroscopy: Testing and Development for Real-Time Isotopic Measurements from Leaf to Ecosystem Scale Carbon Dioxide Exchange (2005) (0)
- Identifying Markers for Pancreatic Cancer by Gene (2017) (0)
- Nuclear DNA Mutations Cancer Offers a ' ' Mass ' '-ive Advantage over Detection of Detection of Mitochondrial DNA Mutations in Pancreatic Updated (2001) (0)
- Hereditary pancreatic cancer (2011) (0)
- Identifying Markers for Pancreatic Cancer by Gene Expression 1 (2005) (0)
- Advances in Brief Dpc 4 Transcriptional Activation and Dysfunction in Cancer Cells 1 (2006) (0)
- Colorectal neoplasia injuvenilepolyposis or juvenile polyps (1991) (0)
- Organ size increases with obesity and correlates with cancer risk (2020) (0)
- Genomic Survey of Distal Bile Duct Carcinoma by Comparative Genomic Hybridization and Karyotype Analysis (2012) (0)
- “Selective cell death mediated by small conditional RNAs” is not selective (2013) (0)
- Acknowledgement to Reviewers (2007) (0)
- Pancreatic Cancer: Recognizing an Hereditary Predisposition (1997) (0)
- Bi-allelic inactivation of the BRCA2 gene occurs after K-ras mutations in pancreatic precursor lesions from patients with germiline BRCA2 mutations (1998) (0)
- Determining Recovery Times from Pharmacologic Effect (1994) (0)
- Pancreas and Biliary Tree (2015) (0)
- Tunable Diode Laser Measurements of Leaf-Scale Carbon Isotope Discrimination adn Ecosystem Respired Carbon and Oxygen Isotope Ratios in a Semi-arid Woodland (2005) (0)
- Testing and development of a Tunable Diode Laser for measurements of leaf to ecosystem stable isotope composition of carbon dioxide exchange (2005) (0)
- The pancreas cancer genome project (1997) (0)
- Malignant granular cell tumor? (1986) (0)
- Correspondence re: M. S. van der Heijden et al., Fanconi Anemia Gene Mutations in Young-onset Pancreatic Cancer. Cancer Res., 63: 2585-2588, 2003 [2] (multiple letters) (2003) (0)
- 221 Ductal adenocarcinoma Ductal adenocarcinoma of the pancreas (2006) (0)
- Thee SMAD4 Protein and Prognosi s of Pancreatic Ductall Adenocarcinoma (2007) (0)
- Techniques et reactifs facilitant la transcription (2001) (0)
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What Schools Are Affiliated With Scott E. Kern?
Scott E. Kern is affiliated with the following schools:
